151. Dementia in motor neuron disease: reviewing the role of MRI in diagnosis
- Author
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Antonio José da Rocha, Renato Hoffmann Nunes, and Antonio Carlos Martins Maia Jr.
- Subjects
frontotemporal dementia ,magnetic resonance ,motor neuron disease ,amyotrophic lateral sclerosis ,frontotemporal lobe degeneration ,Neurosciences. Biological psychiatry. Neuropsychiatry ,RC321-571 - Abstract
ABSTRACT The superimposed clinical features of motor neuron disease (MND) and frontotemporal dementia (FTD) comprise a distinct, yet not fully understood, neurological overlap syndrome whose clinicopathological basis has recently been reviewed. Here, we present a review of the clinical, pathological and genetic basis of MND-FTD and the role of MRI in its diagnosis. In doing so, we discuss current techniques that depict the involvement of the selective corticospinal tract (CST) and temporal lobe in MND-FTD.
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