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The aim of this study is to review the effects of aerobic exercise on asthma control and quality of life in adult patient populations. Randomized controlled trials and prospective studies published between January 2012 and April 2022 were searched in Scopus, Web of Science, and PubMed databases. We followed pre-specified inclusion criteria and excluded manuscripts that studied pediatric populations and those that did not study asthma control or quality of life. We included ten randomized controlled trials and four prospective studies from a combined 2286 search results. Of the included studies, all but three studies found significant improvement in asthma control and quality of life after aerobic intervention. The method of measuring aerobic intervention varied among the studies. Statistical significance was consistent among studies that used maximal heart rate and peak power output to measure intervention. Aerobic exercise intervention can improve asthma control and quality of life in both the acute and chronic response phase. Aerobic activity can be measured by various methods, but in this review, there were no significant adverse events with activity. Higher quality studies are necessary to confirm these results. [ABSTRACT FROM AUTHOR]

Objectives : To determine the feasibility of a randomized controlled trial (RCT) examining outdoor walking on knee osteoarthritis (KOA) clinical outcomes and magnetic resonance imaging (MRI) structural changes. Method: This was a 24-week parallel two-arm pilot RCT in Tasmania, Australia. KOA participants were randomized to either a walking plus usual care group or a usual care control group. The walking group trained 3 days/week. The primary outcome was feasibility assessed by changes being required to the study design, recruitment, randomization, program adherence, safety, and retention. Exploratory outcomes were changes in symptoms, physical performance/activity, and MRI measures. Results: Forty participants (mean age 66 years (SD 1.4) and 60% female) were randomized to walking (n = 24) or usual care (n = 16). Simple randomization resulted in a difference in numbers randomized to the two groups. During the study, class sizes were reduced from 10 to 8 participants to improve supervision, and exclusion criteria were added to facilitate program adherence. In the walking group, total program adherence was 70.0% and retention 70.8% at 24 weeks. The walking group had a higher number of mild adverse events and experienced clinically important improvements in symptoms (e.g., visual analogue scale (VAS) knee pain change in the walking group: − 38.7 mm [95% CI − 47.1 to − 30.3] versus usual care group: 4.3 mm [− 4.9 to 13.4]). Conclusions: This study supports the feasibility of a full-scale RCT given acceptable adherence, retention, randomization, and safety, and recruitment challenges have been identified. Large symptomatic benefits support the clinical usefulness of a subsequent trial. Trial registration number: 12618001097235. Key Points • This pilot study is the first to investigate the effects of an outdoor walking program on knee osteoarthritis clinical outcomes and MRI joint structure, and it indicates that a full-scale RCT is feasible. • The outdoor walking program (plus usual care) resulted in large improvements in self-reported knee osteoarthritis symptoms compared to usual care alone. • The study identified recruitment challenges, and the manuscript explores these in more details and provides recommendations for future studies. [ABSTRACT FROM AUTHOR]

To study the association of the type and intensity level of exercise with the 10-year incidence of cardiovascular disease (CVD) in a sample of adult men and women in the Attica region of Greece. METHOD An epidemiological survey, the ATTICA study, was conducted during the period 2002-2012; 1,514 men and 1,528 women, aged 18-89 years, with no cardiovascular or other chronic diseases, were enrolled voluntarily at baseline examination. The data on 2,020 participants who provided accurate information on 10-year CVD incidence, and demographic, clinical and behavioral characteristics, were used in the final analysis for this study. Regarding physical activity, participants were classified into subgroups, according to the type, i.e., aerobic, resistance or mixed exercise, and intensity, i.e., low, moderate or high, as measured using metabolic equivalence of energy expenditure (MET). RESULTS In the male participants, an independent protective role of aerobic exercise was demonstrated, compared to no exercise, in reducing CVD risk by 43% (95% confidence interval [CI]: 0.34, 0.75). The contribution of specific forms of exercise, including walking and participation in team sports, in preventing the development of CVD, also appeared to be significant. Engaging in moderate-intensity exercise, i.e., 3-6 METs, compared with low-intensity exercise, i.e., 0-3 METs, was associated with a 51% reduction in CVD morbidity and mortality (95% CI: 0.27, 0.87), in the male participants, after adjusting for confounding factors. An inadequate, low intensity level of physical activity (<3 METs) was reported by the majority of the study participants, specifically, 56.8%. CONCLUSIONS These findings support the beneficial role of moderate-intensity aerobic physical activity in the protection of cardiovascular health in adults, and particularly in men, and highlight the need for formulation of more effective strategies to enhance physical activity levels in the adult population of Attica. [ABSTRACT FROM AUTHOR]

OBJECTIVE: Post-COVID-19 patients complained of pain, fatigue, breathlessness, and reduction in quality of life which required planned intervention. This study aimed to compare the impact of 10 weeks of low vs. moderate-intensity aerobic training on physical fitness, psychological status, and quality of life in post-COVID-19 older subjects. PATIENTS AND METHODS: 72 patients were randomized into 3 equal groups, moderate-intensity exercise (MIG, n = 24), low-intensity exercise (LIG, n = 24), and control group (CG, n = 24). The exercise was done 40 min/4 times per week for 10 weeks. We measured exercise capacity using the six-minute walking test, 1 min sit-to-stand test, post-COVID-19 functional scale (PCFS), and quality of life using the SF-36 questionnaire and HAMILTON Anxiety and Depression Scale (HADS). RESULTS: There was no difference between groups regarding the demographic and most clinical characteristics of the subjects. Compared with CG there were statistically significant improvements in studying groups (MIG and LIG) with (p < 0.05) in most outcomes and the improvement was higher in MIG than in LIG in most outcomes. CONCLUSIONS: 10-week moderate-intensity and low-intensity aerobic training programs are effective with superior effect to moderate-intensity. Moderate-intensity aerobic exercise is more effective and feasible in post-discharge COVID-19 older subjects regarding exercise capacity, quality of life, and psychological status than low-intensity aerobic exercise. [ABSTRACT FROM AUTHOR]

Incorporating a gym or fitness facility into a lifestyle-focused clinic is potentially one of the most critical facets of the patient-focused care, especially for those with obesity, cardiometabolic disease, and all types of diabetes mellitus. The evidence for prioritizing physical activity and exercise as medicine is well-researched and universally recommended as first-line therapy plus prevention of many chronic disease states. Having a fitness center on-site as part of any clinic could improve patient utilization, reduce barrier to entry, and decrease hesitation to engage in exercise like resistance training. While the conceptualization may seem simple, the pragmatic application and implementation takes proper planning. Developing such a gym will depend upon gym size preference, program development, cost, and available personnel. Thought needs to be put into deciding which type of exercise and ancillary equipment, ranging from aerobic or resistance machines to free weights, will be included and in what format. Fee and payment options should be carefully considered to assure the budget works financially for both the clinic and patient population. Finally, graphic examples of clinical gyms are described to convey the potential reality of such an optimal setting. [ABSTRACT FROM AUTHOR]

Introduction: M. aviumsubsp. hominissuis (M. avium) is an intracellular, facultative bacterium known to colonize and infect the human host through ingestion or respiratory inhalation. The majority of pulmonary infections occur in association with pre-existing lung diseases, such as bronchiectasis, cystic fibrosis, or chronic obstructive pulmonary disease. M. avium is also acquired by the gastrointestinal route in immunocompromised individuals such as human immunodeficiency virus HIV-1 patients leading to disseminated disease. A hallmark of M. avium pulmonary infections is the ability of pathogen to form biofilms. In addition, M. avium can reside within granulomas of low oxygen and limited nutrient conditions while establishing a persistent niche through metabolic adaptations. Methods: Bacterial metabolic pathways used by M. avium within the host environment, however, are poorly understood. In this study, we analyzed M. avium proteome with a focus on core metabolic pathways expressed in the anaerobic, biofilm and aerobic conditions and that can be used by the pathogen to transition from one environment to another. Results: Overall, 3,715 common proteins were identified between all studied conditions and proteins with increased synthesis over the of the level of expression in aerobic condition were selected for analysis of in specific metabolic pathways. The data obtained from the M. avium proteome of biofilm phenotype demonstrates in enrichment of metabolic pathways involved in the fatty acid metabolism and biosynthesis of aromatic amino acid and cofactors. Here, we also highlight the importance of chloroalkene degradation pathway and anaerobic fermentationthat enhance during the transition of M. avium from aerobic to anaerobic condition. It was also found that the production of fumarate and succinate by MAV_0927, a conserved hypothetical protein, is essential for M. avium survival and for withstanding the stress condition in biofilm. In addition, the participation of regulatory genes/proteins such as the TetR family MAV_5151 appear to be necessary for M. avium survival under biofilm and anaerobic conditions. Conclusion: Collectively, our data reveal important core metabolic pathways that M. avium utilize under different stress conditions that allow the pathogen to survive in diverse host environments. [ABSTRACT FROM AUTHOR]

Fitness of fish is assumed to be influenced by locomotion performance, but empirical evidence linking swimming capacity to survival in nature remains sparse. Poor triploid (3N) fish aerobic swimming performance in conjunction with production of sibling diploid (2N) and 3N populations of genetically identical origin to minimize variability among compared populations make 3N trout an informative system to test hypotheses about fitness consequences of fish locomotion. Here, we ask if reduced survival of 3N relative to 2N trout in natural ecosystems during periods of high temperature relate to a lower aerobic swimming capacity and aerobic scope of 3N compared with 2N conspecifics. Three-yearly cohorts of conspecific 2N and 3N hatchery-reared, yearling rainbow trout were ranked for swimming endurance, externally marked for their endurance quantile, and then stocked into two lakes as yearlings to quantify their survival in the wild over summer as a function of ploidy, temperature and endurance; all while tracking temperature and depth habitat utilization via telemetry. As expected, 3N swimming endurance was lower than that of 2N, but with considerable individual overlap. Aerobic swimming endurance, especially for 3N, was predictive of summer survival in a warm lake where piscivorous birds potentially exerted high predation pressure, resulting in low fish survival. This empirical evidence of a connection between swimming endurance and fitness provides support for long held assumptions of this relationship and could inform future sport fishing stocking industry practices to match fish strains to ideal habitats. [ABSTRACT FROM AUTHOR]

Concentrations of metals along with pH, potential redox (Eh), total dissolved solid (TDS), electrical conductivity (EC) and salinity were measured for sediments of different layers, pore and surface water in the Anzali wetland. Also, the diffusive flux of metals was calculated ad compared with the values in other aquatic bodies. The abundance of metals in sediments was Al > Fe > Ca > Ti > Mn > Zn > V > Cr > Ni > Cu > Pb > Co > As > Mo > Ag > Cd, while the pore-water results indicated a different concentration profile: Ca > Mn > Fe > Al > V > Mo > As > Ni > Cu > Co. Anzali wetland is classified within a high ecological risk. Pore-water toxicity test showed it is in non-polluted condition. Eh–pH diagrams showed that all species of elements are in a stable state in surface and pore-waters. However, Mn and Co (in some layers) are in soluble form and free ions and thus are bioavailable to the organisms. V and As are also present in the form of hydrogen compounds and Ni in the form of hydroxides, therefore, they are toxic to aquatic animals due to their solubility and ionic forms. Diffusive fluxes for As, Al, Fe, Ca, Cu, Mn, Mo, Ni and V are 0.43, 1.80, 48.52, 43,147.50, 0.12, 1.47, 0.15, 1.28, 0.21 µg/m2/day, respectively. Cluster analysis showed that in a solid phase of sediments, elements such as Cr, As and Ti are of petroleum and terrestrial origin. In pore-waters, Cu is of petroleum and biological origin, and Mo, As, Cu and Co are controlled by pH. [ABSTRACT FROM AUTHOR]

Older adults (? 65 years) are recommended to participate in regular exercise to maintain health in late adulthood. The impact of long-term (20+ years) exercise training that align with the American College of Sports Medicine's (ACSM) recommended guidelines has not been evaluated for older adults. To address this, a systematic review and meta-analyses were performed regarding the effects of long-term exercise training on older adult aerobic capacity, muscular fitness, and body composition that meet the ACSM's recommendation for weekly training volume. Ten studies with individuals that performed cardiorespiratory or resistance exercise met the inclusion criteria for the systematic review. Data from five included studies were analyzed in meta-analyses to determine the relationship between the effects of cardiorespiratory training on fitness and body composition measured in the same subjects. Main findings include higher cardiorespiratory fitness (MD: +11.36 mL/kg/min, 95% CI: 5.63 to 17.09 mL/kg/min, p < 0.01) in older adults who performed long-term cardiorespiratory exercise that was found in conjunction with lower percent body fat (MD: -5.41%, 95% CI: -7.65 to -3.17%, p < 0.01). Higher volume of cardiorespiratory exercise beyond the minimum recommendations did not impact benefits. Additionally, resistance-trained older adults showed greater muscular strength and lower percent body fat with comparable cardiorespiratory fitness to sedentary older adults. These findings primarily highlight a preservation of cardiorespiratory fitness and lower risk of mortality and cardiometabolic disease risk for older adults who participate in long-term cardiorespiratory and exercise that meet the ACSM's recommended weekly training volume. [ABSTRACT FROM AUTHOR]

As there is no curative treatment for dementia, including Alzheimer's disease (AD), it is important to establish an optimal nonpharmaceutical preventive intervention. Physical inactivity is a representative modifiable risk factor for dementia, especially for AD in later life (>65 years). As physical activity and exercise are inexpensive and easy to initiate, they may represent an effective nonpharmaceutical intervention for the maintenance of cognitive function. Several studies have reported that physical activity and exercise interventions are effective in preventing cognitive decline and dementia. This review outlines the effects of physical activity and exercise-associated interventions in older adults with and without cognitive impairment and subsequently summarizes their possible mechanisms. Furthermore, this review describes the differences between two types of physical exercise—open-skill exercise (OSE) and closed-skill exercise (CSE)—in terms of their effects on cognitive function. Aerobic physical activity and exercise interventions are particularly useful in preventing cognitive decline and dementia, with OSE exerting a stronger protective effect on cognitive functions than CSE. Therefore, the need to actively promote physical activity and exercise interventions worldwide is emphasized. [ABSTRACT FROM AUTHOR]

This study investigated the effect of compaction, aeration and addition of a naturally mycotoxin contaminated ryegrass silage (MCS) containing 1803 µg/kg DM penicillic acid, on the nutritional value and mycotoxin content after ensiling and subsequent aerobic stability of ryegrass Lolium perenne silage (second-cut, June 2020, UK). Mini silos (30 L) were filled with differential compaction (500 kg FW/m3 and 333 kg FW/m3), aeration by injection of air (1L per 48h for 30d then 1L per 7d) and addition of MCS (1.5 g/kg FW ensiled forage) in a 2×2×2 factorial design. During ensilage, mean CO2% (kg FW) in the aerated silos increased with low compaction. Crude protein (CP) increased and ash decreased with aeration. Mean silage fermentation end products acetic (AA), lactic (LA) and propionic acid (PA) concentrations increased with MCS. PA concentration increased with aeration/low compaction. LA decreased and ethanol increased with low compaction. Mycotoxin profiles differed between the silages on opening and after 14-days incubation in aerobic conditions with disappearance of fusarenon X and penicillic acid and appearance of mycophenolic acid and roquefortine C (318 µg/kg DM and 890 µg/kg DM). Addition of MCS, increased the concentration of penicillic acid on opening with an interaction with aeration (80.6µg/kg DM MCS × aerated, 40.0 µg/kg DM in the MCS × sealed). Aerobic stability was affected by aeration and low compaction with reduced time taken to heat to +5°C and +10°C above ambient temperature, higher rate of increase in pH and higher cumulative temperatures to the first peak temperature. Higher mycotoxin concentration at opening had a similar effect increasing time to heat +5°C and +10°C above ambient temperatures in aerobic conditions. Regression analysis showed predominantly direct relationships between silage fermentation end-product concentrations and aerobic stability. This study revealed interactions between silage bacteria and fungi activity from the concentrations of fermentation end-products and mycotoxins during ensilage and subsequent aerobic spoilage. The results supported current best practice for silage making, promoting conditions for improved preservation and aerobic stability. The addition of MCS had unexpected positive effects. However, factors associated with the MCS benefiting aerobic stability were not determined.

Objective: The purpose of this study was to examine the immediate and short-term, sustained effects of two virtual interventions, WeActive, an aerobic and resistance training program, and WeMindful, a mindful exercise, in reducing anxiety and improving mindfulness among college students during the COVID-19 pandemic. Methods: Participants were 60 students from a large Midwestern university who were randomly assigned to either the WeActive group (n = 36) or the WeMindful group (n = 24). The WeActive group participated in two virtual 30 min aerobic and resistance training sessions per week (WeActive) and the WeMindful group participated in two virtual 30 min mindful exercise sessions per week for eight weeks. All participants completed the Generalized Anxiety Disorder scale and the Five Facet Mindfulness Questionnaire through Qualtrics at three time points: one week prior to (pre-test), one week after (post-test), and six weeks after (follow-up) the intervention. Results: A repeated-measures ANOVA revealed a significant main effect of time on anxiety (F = 7.51, η2 = 0.036, p = 0.001) in both groups. WeActive significantly decreased anxiety scores between the pre-test and follow-up (t = 2.7, p = 0.027) and post-test and follow-up (t = 3.1, p = 0.007), and WeMindful significantly decreased anxiety scores between the post-test and follow-up (t = 0.641, p = 0.028). For mindfulness, there was a significant main effect of time in both groups (F = 3.91, η2 = 0.009, p = 0.025), where only WeMindful significantly increased mindfulness from the pre-test to follow-up (t = −2.7, p = 0.025). Conclusions: Anxiety decreased significantly in both the WeActive and WeMindful groups and mindfulness increased significantly in the WeMindful group. Furthermore, the decrease in anxiety was sustained in a short-term period following the end of the intervention.

This study aimed (1) to assess the validity of a modified method (Mmod) based on heart rate (HR)—oxygen uptake (VO2) regression functions to calculate total energy costs (Wtotal) and aerobic (Waer) and anaerobic alactic energy contribution (Wpcr) and (2) to analyse the physiological and energetic demands of high-level pommel horse routines (PH routines). The Mmod was developed because VO2 measurements are limited during high-level PH routines. Answering Part 1, nine male artistic gymnasts performed a PH routine where energy costs were calculated from VO2 measurements and then compared with energy costs determined from the HR- VO2 regressions of Mmod’s two additional tests. Using the concordance correlation coefficient (CCC) and Deming regression, Waer (CCC = 0.955), Wpcr (CCC = 0.999), and Wtotal (CCC = 0.990) show substantial to almost perfect validity without constant or proportional bias. Data from eight further gymnasts performing a high-level PH routine and a graded exercise test (GXT), as well as four data sets from Part 1, were used to determine physiological and energetic demands using Mmod. VO2 and HR during PH routines reached 86.1% and 90.4% of the maximal values during GXT. Wpcr was 47.0%, anaerobic lactic energy contribution (Wblc) was 29.7%, and Waer was 23.3% of Wtotal required during PH routines. Summarising the energetic demands of high-level PH routines, they are mainly anaerobic, where Wpcr provides the largest energy share. Waer provides a substantial part of Wtotal and should therefore also be specifically trained.

A straightforward and convenient protocol was established for the synthesis of thiophosphates and 3-sulfenylated indoles via low-valent-tungsten-catalyzed aerobic oxidative cross-dehydrogenative coupling reactions. These reactions occur under mild conditions and simple operations with commercially available starting materials, processing the advantage of excellent atom and step economy, broad substrate scope, and good functional groups tolerance. Moreover, this transformation could be practiced on the gram scale, which exhibits great potential in the preparation of drug-derived or bioactive molecules.

Today, plastic materials are mostly made from fossil resources, and they are characterized by their long lifetime and pronounced persistence in the open environment. These attributes of plastics are one cause of the ubiquitous pollution we see in our environment. When plastics end up in the environment, most of this pollution can be attributed to a lack of infrastructure for appropriately collecting and recycling plastic waste, mainly due to mismanagement. Because of the huge production volumes of plastics, their merits of being cheap to produce and process and their recalcitrance have turned into a huge disadvantage, since plastic waste has become the end point of our linear economic usage model, and massive amounts have started to accumulate in the environment, leading to microplastics pollution and other detrimental effects. A possible solution to this is offered by “bioplastics”, which are materials that are either (partly) biobased and/or degradable under defined conditions. With the rise of bioplastics in the marketplace, several standards and test protocols have been developed to assess, certify, and advertise their properties in this respect. This article summarizes and critically discusses different views on bioplastics, mainly related to the properties of biodegradability and biobased carbon content; this shall allow us to find a common ground for clearly addressing and categorizing bioplastic materials, which could become an essential building block in a circular economy. Today, bioplastics account for only 1–2% of all plastics, while technically, they could replace up to 90% of all fossil-based plastics, particularly in short-lived goods and packaging, the single most important area of use for conventional plastics. Their replacement potential not only applies to thermoplastics but also to thermosets and elastomers. Bioplastics can be recycled through different means, and they can be made from renewable sources, with (bio)degradability being an option for the mismanaged fraction and special applications with an intended end of life in nature (such as in seed coatings and bite protection for trees). Bioplastics can be used in composites and differ in their properties, similarly to conventional plastics. Clear definitions for “biobased” and “biodegradable” are needed to allow stakeholders of (bio)plastics to make fact-based decisions regarding material selection, application, and end-of-life options; the same level of clarity is needed for terms like “renewable carbon” and “bio-attributed” carbon, definitions of which are summarized and discussed in this paper.

Background: Insufficient physical activity (PA) is associated with numerous chronic diseases and premature mortality, and the challenge of meeting recommended PA guidelines is exacerbated in the winter. Snowmobiling can potentially contribute to PA accumulation, but the objective metabolic and physical demands are unclear. The purpose of this study was to assess the physical demands of riding a snowmobile. Methods: Habitual snowmobile riders responded to a survey describing a typical ride (n = 4015). Using this data, terrain-specific testing courses were created, and recreational snowmobile riders (n = 40) participated in a scaled representative ride (21 [8] min) while aerobic metabolism (VO2) and muscular fatigue were quantified. Results: The mean VO2 while riding, irrespective of terrain, was 18.5 (8.4) mL⋅kg-1⋅min-1, with significant differences based on geographic location (13.4 [5.2] vs 25.7 [6.6] mL⋅kg-1⋅min-1, P < .001). Muscular fatigue was apparent in maximal handgrip (-7% [8%], P < .001) across both riding terrains, but not lower body power, suggesting a greater influence of an upper body strength component. Conclusions: Snowmobiling is an activity that generally falls within the moderate-intensity activity range and involves both aerobic fitness and muscular strength. There were substantial differences in demand between terrains, suggesting that additional benefits may be conferred from mountain riding as it was more metabolically demanding. [ABSTRACT FROM AUTHOR]

The impact of animal protein blend supplements in endurance athletes is scarcely researched. The authors investigated the effect of ingesting an admixture providing orange juice and protein (PRO) from beef and whey versus carbohydrate alone on body composition and performance over a 10-week training period in male endurance athletes. Participants were randomly assigned to a protein (CHO + PRO, n = 15) or a nonprotein isoenergetic carbohydrate (CHO, n = 15) group. Twenty grams of supplement mixed with orange juice was ingested postworkout or before breakfast on nontraining days. Measurements were performed pre- and postintervention on body composition (by dual-energy X-ray absorptiometry), peak oxygen consumption (...O2peak), and maximal aerobic speed. Twenty-five participants (CHO + PRO, n = 12; CHO, n = 13) completed the study. Only the CHO + PRO group significantly (p < .05) reduced whole-body fat (mean ± SD) (-1.02 ± 0.6 kg), total trunk fat (-0.81 ± 0.9 kg), and increased total lower body lean mass (+0.52 ± 0.7 kg), showing close to statistically significant increases of whole-body lean mass (+0.57 ± 0.8 kg, p = .055). Both groups reduced (p < .05) visceral fat (CHO + PRO, -0.03 ± 0.1 kg; CHO, -0.03 ± 0.5 kg) and improved the speed at maximal aerobic speed (CHO + PRO, +0.56 ± 0.5 km/hr; CHO, +0.35 ± 0.5 km/hr). Although consuming animal protein blend mixed with orange juice over 10 weeks helped to reduce fat mass and to increase lean mass, no additional performance benefits in endurance runners were observed. [ABSTRACT FROM AUTHOR]

Introduction: Considering the reduction of physical activity performed daily in people with spinal cord injury, it is necessary to analyze the interventions based on physical exercises in order to provide recommendations based on evidence. Objectives: To review and evaluate the literature on physical exercise interventions for individuals with SCI, based on the International Classification of Functioning, Disability and Health, as well as physiological parameters for exercise prescription. Method: A systematic review of the literature produced from August 2016 to February 2017 within the PubMed, Embase, Cochrane Library, and MEDLINE databases. Results: Two independent examiners conducted a search in which 223 articles were initially found. A third evaluator verified possible divergences and generated a final list of 25 articles that strictly met the inclusion criteria, 5 of which investigated the effects of aerobic exercise, 2 of resistance training, 2 of balance training, 12 of gait training, and 4 evaluating the combined effect of 2 or more forms of training. Conclusion: Considering studies classified as of high and moderate quality of evidence, positive effects were observed in the domains of structures and functions, in aerobic, resistance training and combined exercises, and in some studies with gait training. In the domain of activities and participation, positive effects were observed in the studies with gait training, balance training, and combined interventions. [ABSTRACT FROM AUTHOR]

Physical activity (PA) and health were compared in younger (YA; 18–44 years), middle-aged (MA; 45–64 years), and older (OA; ≥65 years) adults with disability (PWD), functional limitation (PFL), or without disability (PWoD). Disability occurred in YA (PWD: 2.3%; PFL: 14.3%), MA (PWD: 8.5%; PFL: 23.8%), and OA (PWD: 14.9%; PFL: 26.6%). Not meeting aerobic/muscle-strengthening PA recommendations was frequent in YA (PWD: 50.7%; PFL: 42.5%; PWoD: 35.8%), MA (PWD: 56.7%; PFL: 44.0%; PWoD: 35.6%), and OA (PWD: 57.8%; PFL: 44.1%; PWoD: 33.1%). Among PWD, YA and MA met muscle, strengthening recommendations more frequently than did OA; PFL did more aerobic PA than PWD. The presence of chronic diseases, female gender, White race, lower education, and less income were associated with being PWD or PFL. Those with greater PA were less likely to be PWD or PFL. Results suggest increasing public health efforts to promote healthy lifestyles in MA and OA. [ABSTRACT FROM AUTHOR]

Purpose: To examine the reliability and the maturity-related differences of fatigue thresholds (FTs) among youth males. Methods: Twenty-nine youth males (11–17 y) completed 2 ramp exercise tests on a cycle ergometer. Systemic FTs were calculated from gas exchange and ventilation variables. Localized FTs were calculated from electromyography and near-infrared spectroscopy of the vastus lateralis. All FTs were determined using the maximal distance method and expressed relative to maximal oxygen consumption. All participants were grouped according to the number of years from peak height velocity into PRE- (< −1.5 y), PERI- (−1.5 to +1.5 y) and POST- (> +1.5 y) peak height velocity. Reliability was assessed with intraclass correlation coefficients, and differences between groups were assessed with analysis of variance and Cohen's d coefficients. Results: Analysis of variance revealed significant group differences with PRE having significantly greater systemic pulmonary FTs than POST, while localized muscular FTs were significantly greater in PRE when compared with PERI and POST. All FTs exhibited excellent reliability (intraclass correlation coefficient >.75) in all maturity groups. Conclusion: Maturity status appears to influence the onset of FTs among youth male athletes, with FTs occurring later in younger athletes. Furthermore, all FTs were reliable measures regardless of maturity. [ABSTRACT FROM AUTHOR]

Evidence supports that acute exercise benefits long-term memory. However, it is unclear whether these effects are due to benefits to encoding or consolidation. The purpose of this study was to more effectively isolate encoding and consolidation to advance our understanding of the specific nature of the effects of exercise on long-term memory. Using a within-subject design, participants completed a control session (no exercise), an encoding and consolidation condition (exercise prior to exposure to the memory task, E + C), and a consolidation condition (exercise following exposure). The exercise was 30 min of moderate-intensity cycling. Memory was assessed using the Rey Auditory Verbal Learning Test with recall assessed at 60 min and recall and recognition assessed at 24 hr. Results showed that the E + C condition had significantly better recall at 60 min and 24 hr than the no-exercise condition. This provides additional evidence that acute exercise benefits encoding more than consolidation. [ABSTRACT FROM AUTHOR]

A growing body of research indicates that physical activity (PA) positively impacts cognitive function in youth. However, not all forms of PA benefit cognition equally. The purpose of this review was to determine the effect of different types of chronic PA interventions on cognition in children and adolescents. A systematic search of electronic databases and examination of the reference lists of relevant studies resulted in the identification of 28 studies. Seven categories of PA were identified, based on all possible combinations of three types of PA (aerobic, motor skill, cognitively engaging), and four comparison groups (no treatment, academic, traditional physical education, aerobic). Effect sizes were calculated based on means and SDs at the post-test using Hedge's g formula, which includes a correction for small sample bias. Each study was only entered once in each intervention-comparator category. Full data were provided from 21 studies (28 effect sizes; n=2042 intervention; n=2002 comparison group). Overall, chronic PA interventions had a significant small-to-moderate effect on cognition (0.46). Moderate significant positive effects were identified when PA interventions were compared to no treatment (0.86) or academic content (0.57). A non-significant effect was noted when PA interventions were compared to traditional physical education (0.09) or aerobic group (0.80). However, high heterogeneity in pooled effect sizes suggests that important differences in the qualitative characteristics of the PA intervention and comparison interventions may exist. Effect sizes based on comparisons between different types of PA interventions and comparison groups are discussed in order to identify possible directions for future investigations. We conclude that chronic PA interventions have a positive impact on cognitive function in youth, but more systematic research is needed in this area.

IntroductionM. avium subsp. hominissuis (M. avium) is an intracellular, facultative bacterium known to colonize and infect the human host through ingestion or respiratory inhalation. The majority of pulmonary infections occur in association with pre- existing lung diseases, such as bronchiectasis, cystic fibrosis, or chronic obstructive pulmonary disease. M. avium is also acquired by the gastrointestinal route in immunocompromised individuals such as human immunodeficiency virus HIV-1 patients leading to disseminated disease. A hallmark of M. avium pulmonary infections is the ability of pathogen to form biofilms. In addition, M. avium can reside within granulomas of low oxygen and limited nutrient conditions while establishing a persistent niche through metabolic adaptations.MethodsBacterial metabolic pathways used by M. avium within the host environment, however, are poorly understood. In this study, we analyzed M. avium proteome with a focus on core metabolic pathways expressed in the anaerobic, biofilm and aerobic conditions and that can be used by the pathogen to transition from one environment to another.ResultsOverall, 3,715 common proteins were identified between all studied conditions and proteins with increased synthesis over the of the level of expression in aerobic condition were selected for analysis of in specific metabolic pathways. The data obtained from the M. avium proteome of biofilm phenotype demonstrates in enrichment of metabolic pathways involved in the fatty acid metabolism and biosynthesis of aromatic amino acid and cofactors. Here, we also highlight the importance of chloroalkene degradation pathway and anaerobic fermentationthat enhance during the transition of M. avium from aerobic to anaerobic condition. It was also found that the production of fumarate and succinate by MAV_0927, a conserved hypothetical protein, is essential for M. avium survival and for withstanding the stress condition in biofilm. In addition, the participation of regulatory genes/proteins such as the TetR family MAV_5151 appear to be necessary for M. avium survival under biofilm and anaerobic conditions.ConclusionCollectively, our data reveal important core metabolic pathways that M. avium utilize under different stress conditions that allow the pathogen to survive in diverse host environments.

Attention deficit hyperactivity disorder (ADHD) results in significant functional impairment. Current treatments, particularly for adults, are limited. Previous research indicates that exercise may offer an alternative approach to managing ADHD, but research into different types of exercise and adult populations is limited. The aim of this study was to examine the effects of acute exercise (aerobic cycling vs mind-body yoga exercises) on symptoms of ADHD in adults. Adults with ADHD (N = 82) and controls (N = 77) were randomly allocated to 10 min of aerobic (cycling) or mind-body (Hatha yoga) exercise. Immediately before and after exercise, participants completed the Test of Variables of Attention task, Delay Discounting Task, and Iowa Gambling Task to measure attention and impulsivity. Actigraphy measured movement frequency and intensity. Both groups showed improved temporal impulsivity post-exercise, with cycling beneficial to all, whilst yoga only benefited those with ADHD. There were no effects of exercise on attention, cognitive or motor impulsivity, or movement in those with ADHD. Exercise reduced attention and increased movement in controls. Exercise can improve temporal impulsivity in adult ADHD but did not improve other symptoms and worsened some aspects of performance in controls. Exercise interventions should be further investigated. [ABSTRACT FROM AUTHOR]

Objective: This study aimed to provide, through an umbrella review, an overview of the effect of single exercise interventions during pregnancy on gestational diabetes mellitus (GDM) and hypertensive disorders of pregnancy (HDP). Also, to update the current evidence through an updated meta‐analysis. Design: Umbrella review. Setting: PubMed, EMBASE, Web of Science, Cochrane database of systematic reviews, Epistemonikos, SPORTDiscus, Clinicaltrials.gov, and PROSPERO register were searched from the database inception until August 2021. Population: Peer‐reviewed systematic reviews and meta‐analyses of randomised controlled trials (RCTs) and RCTs samples. Methods: Random‐effects model was used to calculate relative risk with 95% confidence interval in the updated meta‐analysis. The reference category was the groups that received usual prenatal care. AMSTAR 2 and the Cochrane Collaboration tool were used to assess the quality and GRADE approach was used to assess the overall certainly of evidence. Main outcome measures: GDM and HDP relative risk. Results: Twenty‐three systematic reviews and meta‐analyses; and 63 RCTs were included. Single exercise interventions reduced the incidence of GDM and HDP in most systematic reviews and meta‐analyses. Moreover, exercise interventions during pregnancy decrease the incidence of developing GDM and GH, particularly when they are supervised, have a low to moderate intensity level, and are initiated during the first trimester of pregnancy. Conclusion: Based on the findings, obstetric and physical exercise professionals could recommend exercise interventions during pregnancy as an effective strategy to improve maternal outcomes. [ABSTRACT FROM AUTHOR]

Aerobic respiration evolved by bricolage, with modules cobbled together as microbial biochemistry coevolved with Earth's geochemistry. The mitochondrial electron transport chain represents a patchwork of respiratory modules inherited from microbial methanogenesis, iron oxidation, anoxygenic photosynthesis, and denitrification pathways, and preserves a biochemical record of Earth's redox environment over its four-billion-year history. Imprints of the anoxic early Earth are recognizable in Complex I's numerous iron-sulfur cofactors and vestigial binding sites for ferredoxin, nickel-iron, and molybdopterin, whereas the more recent advent of oxygen as a terminal electron acceptor necessitated use of heme and copper cofactors by Complex IV. Bricolage of respiratory complexes resulted in supercomplexes for improved electron transfer efficiency in some bacteria and archaea, and in many eukaryotes. Accessory subunits evolved to wrap mitochondrial supercomplexes for improved assembly and stability. Environmental microbes with 'fossil' proteins that are similar to ancestral forms of the respiratory complexes deserve further scrutiny and may reveal new insights on the evolution of aerobic respiration. The mitochondrial electron transport chain is derived from modular enzyme complexes assembled from microbial pathways, including methanogenesis, iron oxidation, anoxygenic photosynthesis, and denitrification. The vestiges of ancient anaerobic respiratory complexes are especially evident in Complex I, which represents a bricolage of modules, each of which originated with a function different from that which they have today. Ancestral Complex II likely ran in the opposite direction for anaerobic respiration and was later co-opted to provide additional reducing power for aerobic respiration. Complex III likely originated in anaerobic anoxygenic photosynthetic bacteria. Ancestral Complex IV was likely involved in denitrification, and iron-oxidizing bacteria may have contributed to adaptation of Complex IV to higher oxygen levels. [ABSTRACT FROM AUTHOR]

Concussion is a type of mild traumatic brain injury which results in symptoms within the physical, cognitive, emotional, and sleep domains. Historically, guidelines established by expert opinion have recommended rest during the initial stages of recovery following a concussion until symptom resolution. However, recent recommendations have shifted to advise an initial period of 24–48 h of rest immediately following concussion with the gradual introduction of light-to-moderate intensity aerobic exercise thereafter. Given the relatively recent transition in recommendations, the aim of this review is to provide an overview of the current literature on the efficacy of aerobic exercise following concussion. The current literature is limited to studies assessing the impact of standardized aerobic exercise following concussion. Upon review, literature suggests participating in aerobic exercise below the point of symptom exacerbation is safe in both the acute and chronic post-concussion symptom stages of recovery and does not delay time to medical clearance. Future large-scale randomized controlled trials assessing the impact of aerobic exercise and differences between males and females would help support the current evidence suggesting aerobic exercise could improve time to recovery following concussion and identify any sex differences in response. As well, future studies with the purpose of identifying optimal aerobic exercise volume and intensity in the treatment of concussion could improve the specificity of the current guidelines. [ABSTRACT FROM AUTHOR]

Copyright of Revista Brasileira de Medicina do Esporte is the property of Redprint Editora Ltda. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Turkish Journal of Sport & Exercise / Türk Spor ve Egzersiz Dergisi is the property of Turkish Journal of Sport & Exercise and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Carob-mediated calcium hydroxide nanoparticles (C-CaOH2 NPs) are a type of NPs, newly developed via a green synthesis method, that have demonstrated good in vitro biocompatibility. However, their antibacterial potential has not yet been explored. Both calcium hydroxide and carob are known for their antibacterial potency as bulk materials; thus, we hypothesized that C-CaOH2 NPs may exhibit promising antibacterial efficacy. This study aimed to examine the antibacterial activity of C-CaOH2 NPs against aerobic and anaerobic strains using zone of inhibition (ZOI), minimum inhibitory concentration (MIC), and minimum bactericidal concentration (MBC) tests. The results showed that the Gram-negative aerobic strains are more susceptible than the Gram-positive stains. The most susceptible bacteria were P. aeruginosa, E. coli, and S. aureus, in that order. Conversely, P. micra and E. faecalis were the least susceptible strains. The best recorded ZOIs were at 100 and 150 mg/mL concentrations in all bacteria, with the greatest diameter (11.7 ± 0.6 mm) exhibited in P. aeruginosa. Moreover, the MICs for aerobes were 3.12 mg/mL, except for E. faecalis (0.78 mg/mL) and K. pneumoniae (1.56 mg/mL). MBCs were 12.5 mg/mL for all except P. aeruginosa (3.12 mg/mL) and K. pneumoniae (6.25 mg/mL). The anaerobic strain P. micra exhibited the highest values for both MIC (15.62 mg/mL) and MBC (31.25 mg/mL). The current investigation revealed that C-CaOH2 NPs have intermediate and dose-dependent antibacterial activity that may have variable biomedical applications. [ABSTRACT FROM AUTHOR]

The prawn Macrobrachium rosenbergii post larvae (10.01 ± 2.00 mg) were evaluated using a synbiotic system with different fermentation (anaerobic) and microbial respiration (aerobic) strategies after 35 days. Rice bran, a mix of probiotic microorganisms, alkalizing agents, and water were used in the preparation of the synbiotic. There were five treatments in quadruplicate, consisting of the following: T12|12 = 12 h anaerobic and 12 h aerobic; T12|24 = 12 h anaerobic and 24 h aerobic; T24|0 = 24 h anaerobic; T24|12 = 24 h anaerobic and 12 h aerobic; T24|24 = 24 h anaerobic and 24 h aerobic. The prawns were fed four times a day (40% crude protein) and the main variables of water quality and prawn growth were evaluated. The synbiotic preparation strategies used did not influence the stabilization time of nitrogen compounds in water. There were no differences in the survival and the water quality variables, which remained adequate for the species. For the variables final average weight (mg) and yield (gm−3), treatments T24|24 (221.3 ± 22.0 and 195.4 ± 14.6) and T12|24 (218.2 ± 27.6 and 196.2 ± 33.4) were higher than 24|00 (176.1 ± 24.5 and 151.3 ± 21.6). Thus, it is concluded that a longer preparation time of the fertilizer, especially contemplating the anaerobic and aerobic stages, can promote greater performance of the reared prawns. [ABSTRACT FROM AUTHOR]

Purpose: This study aimed to determine if percent fat-free mass loss (% FFML) after diet alone, diet plus aerobic, or diet plus resistance exercise is a predictor of weight regain in women with overweight. Methods: One hundred and forty-one premenopausal women with overweight (body mass index, 28 ± 1 kg·m−2; age, 35 ± 6 yr) enrolled in a weight loss program to achieve a body mass index <25 kg·m−2 (diet alone, diet plus resistance, or diet plus aerobic exercise) and were followed for 1 yr. Body weight and composition (with dual-energy x-ray absorptiometry) were measured at baseline, after weight loss, and at 1 yr. Results: Participants lost 12.1 ± 2.6 kg of body weight, 11.3 ± 2.5 kg of fat mass, and 0.5 ± 1.6 kg of fat-free mass during the weight loss intervention, followed by weight regain at 1 yr (6.0 ± 4.4 kg, 51.3% ± 37.8%; P < 0.001 for all). % FFML was −3.6 ± 12.4, and a greater % FFML was associated with more weight regain (r = −0.216, P = 0.01, n = 141), even after adjusting for the intervention group (β = −0.07; 95% confidence interval, −0.13 to −0.01; P = 0.017). Conclusions: % FFML is a significant predictor of weight regain in premenopausal women with overweight. These results support strategies for conserving fat-free mass during weight loss, such as resistance training. Future research should try to identify the mechanisms, at the level of both appetite and energy expenditure, responsible for this association. [ABSTRACT FROM AUTHOR]

Purpose: Judo is an intermittent sport, dependent on anaerobic metabolism as well as aerobic metabolism to generate energy during a match; however, there are few reliable tests to measure specific aerobic performance in judo. Thus, the present study aimed to propose a new specific and indirect method to assess the aerobic performance in judo athletes; it determined the inter-rater and test–retest reliability of this new protocol and correlated the new protocol with a valid laboratory test. Method: The participants included 15 men, athletes of judo (age average: 21.59 ± 4.60 years, weight: 80.71 ± 15.93 kg and height: 173.2 ± 6.84 cm). The participants performed three tests: the first test was a graded exercise test (GXT) and the second and third tests were the Judo Aerobic Test (JAT). Results: The test presented high test–retest and inter-rater reliability, the intraclass correlation coefficients (ICC) ranking of 0.68–0.96, the correlation values ranging from.77 to.96, and no statistical differences between means in test and retest (p >.05). The standard error of measurement and the coefficient of variation between raters presented lower than 10%, indicating reproducibility. Moderate and strong correlations were found between JAT and GXT variables. Conclusion: We concluded that the test presents excellent inter-rater and test–retest reliability and a moderate correlation with GXT. [ABSTRACT FROM AUTHOR]

High-temperature aerobic composting has been ever-increasing developed rapidly for the fastest way to make high quality compost without any foul odors. However, the greenhouse gas (GHG) can also be produced during composting, including CH4 and N2O. In this study, a 35-day aerobic co-composting of kitchen waste and yard trimming (chipped stems) was carried out in 60 L forced aerated static composting reactors, in order to reduce the GHG emission during composting. Three commercial microbial agents were also added to compost materials, including the VT1000 compound consortia (VT), Bacillus subtilize (BS), and Bacillus licheniformis (BL). Among them, the addition of fungi was 1.5% of the dry weight of all raw materials. The treatment without bacterial agents was used as the control (CK). Furthermore, CH4 and N2O emissions during composting were monitored to investigate the effect of the microbial agents on the GHG emission. The results showed that the microbial agents significantly accelerated the maturity of compost with the rise of temperature, whereas, relatively reduced the GHG emission in the varying degrees. The duration of high temperature in all treatments was fully met the harmless requirements, in terms of reactor heating. But the treatment with the microbial agents presented the better secondary heating. The fastest temperature recovery and the highest temperature were achieved in the VT, followed by the BS, and the BL was slower than the CK. In maturity, the electric conductivity and pH value in all treatments were met the industrial requirements of compost quality. Specifically, the uninoculated microbial agent failed to the rot standard in the CK treatment. A slightly better compost maturity was obtained in the BS treatment, compared with the VT and BL. Among the GHG emission reduction, the N2O emission was accounted by 76.83%-88.57% of the total as the CO2-C equivalent, indicating the much higher amount than that of CH4. The peaks of emission occurred at the initial and mature stage. The CH4 emission peak occurred at the cooling stage, where the cumulative emissions reached 1.65%-2.40% of the total GHG emissions equivalent. The cumulative CH4 emissions in the four treatments were ranked as the CK>BL>BS>VT in the descending order. As such, the best performances (18.89%) of the CH4 and N2O emission reduction were achieved in the VT and BS treatment, respectively. The reduction rates were 49.22%, 61.86%, and 35.32% in the BS, VT, and BL treatment, respectively. The total GHG emissions equivalent were 95.84 (CK), 52.31 (VT), 42.03 (BS), and 62.49 kg/t (BL). Compared with the CK, the best total GHG mitigation was obtained in the BS treatment, with the reduction rate of 56.15%, the BL treatment was the lowest of 34.80%, while the VT treatment was 45.42%. The N2O abatement was better performed than methane with the inoculants, ranging from 35.32% to 61.87%. Taken together, the best effect was achieved in the treatment with 1.5% BS. Therefore, the microbial agents can be expected to effectively mitigate the GHG for the better quality of composting products. [ABSTRACT FROM AUTHOR]

Background: The benefits derived from supervised aerobic exercise in people living with human immunofeficiency virus– HIV (PLWH) have not yet been clearly identified. Objective: To evaluate the impact of supervised aerobic exercise on immunological, cardiorespiratory, pulmonary, hemodynamic and mental parameters of PLWH. Methods: A systematic review was carried out in accordance to PRISMA guidelines. PubMed, Physiotherapy Evidence Database (PEDro) and Cochrane Central Register of Controlled Trials (CENTRAL) were screened up to August 2021, for the identification of English written randomized trials, with participants aged 18 years and older, at any stage of the disease, with or without co-morbidities. The risk of bias assessment was conducted according to the Cochrane Collaboration's tool for assessing risk of bias. Meta- analyses were conducted using continuous, inverse variance, random-effects model. Results: Ten studies were suitable for meta-analysis based on inclusion criteria. Supervised aerobic exercise appeared to have beneficial effects on depressive symptoms [mean difference (MD)= −4.18 (confidence interval (CI)= (−6.55)–(−1.81), Z = 3.46, p = 0.0005, I2=0%, n = 2], forced expiratory volume in 1 sec [MD = 0.70, CI = 0.39–1.00, Z = 4.41, p < 0.0001, I2=0%, n = 2], and on the maximum oxygen uptake [MD = 1.38, CI = −0.02–2.78, Z = 1.94, p = 0.05, I2=94%, n = 4] of PLWH. No exercise effect was found for CD4 T-cell count (p = 0.16, n = 5), systolic blood pressure (p = 0.91, n = 2) and diastolic blood pressure (p = 0.72, n = 2). Conclusions: Supervised continuous aerobic exercise may improve lung function, depressive symptomatology and aerobic capacity of PLWH, however, the small number of available studies and the high heterogeneity concerning VO2max demonstrate the need for more research in this area. [ABSTRACT FROM AUTHOR]

The purpose of this investigation was to examine the interrelationship between time spent underwater (UW), movement frequency and accompanying blood acid base balance response. Elite artistic swimmers (n = 6) participated in the investigation and were all familiar with the testing procedures. All athletes completed the same choreographed artistic swimming routine. The routine was videoed and the number of movements during each 'lap' of the routine counted. Fingertip capillary blood samples were collected prior to the routine 60 sec post routine for pH, partial pressure of carbon dioxide (pCO2), partial pressure of oxygen (pO2), bicarbonate (HCO3−) and potassium (K+). and lactate (La) concentration (mmol/L). On a separate day an incremental exercise test to exhaustion was performed on a cycle ergometer for determination of maximal oxygen uptake (VO2max). Over half the routine was performed underwater (56 ± 4%). Aside from pCO2 (−1.07 ± 12.29%, p = 0.686), there were significant changes in all variables measured from the BG analysis. VO2peak was significantly correlated to total UW of the routine (r = −0.93; p = 0.007). as well as ∆PO2 r = 0.47 and ∆HCO3 r = 0.51. There was also a significant correlation between total UW and post routine pCO2 (r = 0.86; p = 0.030). There was also a significant correlation between total movements during the routine and post pO2 (r = −0.83; p = 0.044). These data show UW in combination with movement rate during a AS routine imfluence the metabolic response to the exercise. In addition, VO2max represents an important performance variable influencing AS performance. [ABSTRACT FROM AUTHOR]

Background and purpose: Recent research suggests that obese people are up to 80 times more likely to develop type 2 diabetes than those with a normal BMI. Besides, obesity, inadequate physical activity, and unhealthy diets are the main causes of this metabolic disease. The purpose of this study was to investigate the effect of six weeks of high-intensity interval training on muscle expression of Fat mass and obesity-associated protein (FTO) and Peroxisome proliferator activator receptor gamma (PPAR-γ) in obese diabetic rats. Material and methods: This experimental study was carried out on 12 male Wistar rats (220±20 g bodyweight and 10 weeks old). Animals received a high-fat diet within six weeks, and then in order to induce type 2 diabetes, an intraperitoneal injection of a single dose of 30 mg/kg freshly prepared streptozotocin (STZ) (Sigma, USA) solved in citrate buffer (pH 4.5) was performed. Diabetic rats were divided into two (High-Intensity Interval Training and control) groups randomly. HIIT program included five sessions of 30 minutes per week. 48 hours after the last training session, the outcomes were measured. The muscle expression of FTO and PPAR-γ was measured using the real-time PCR method. Independent samples t-test and Analysis of covariance (ANCOVA) were applied to compare the means. Results: The expression of FTO (P

Attention deficit hyperactivity disorder (ADHD) is one of the most commonly neurodevelopmental disorders with a complex symptomatology in children, and frequently suffer from deficits in executive functions and motor abilities. Although medication-based treatments usually have a positive effect, possible side effects may result in a need for an adjunctive intervention. Present studies show positive effect of physical exercise on cognitive function. Therefore, the purpose of the current study is thoroughly examine the effects of physical exercise in children with ADHD. Preliminary evidence shows both acute and chronic physical exercise are beneficial to ADHD symptoms, executive function, and motor abilities. Benefits of acute exercise may gradually accumulate over time. Such benefits reflect the positive correlation between cognition and physical activity, and these benefits will also lead to changes in executive function after long-term training. Aerobic could induce to increase the neurotransmitter ie. serotonin, dopamine, brain-derived neurotrophic factor (BDNF) and brain blood flow. Perceptual motor and meditation could lead to neuroplasticity in nerve cells and synaptic connections; furthermore, strengthening the sensory-motor base contributes to the improvement of attention. An exercise program for children with ADHD include to moderate to high intensity interval training and cognitive tasks are suitable. The preliminary state of the evidence supports physical exercise as an adjunctive treatment for ADHD at this time.

The use of disposable diapers is increasing every year, increasing generated diaper wastes every year. In Surabaya, diaper wastes have become an important issue when they are not treated properly. These diaper wastes will end up in water bodies and cause pollution. One of the technologies that can be used to treat diaper wastes is composting. Disposable diaper wastes consist of high lignocellulose and C content. It is necessary to mix diaper wastes and other wastes with high N content as a co-substrate, so that the optimum C/N ratio of composting can be achieved. In this research, vegetables wastes were used. The Objective of the research was to determine the effect of vegetable wastes adding as a co-substrate in composting of disposable diapers and volatile solid (VS), C-organic, and Total Nitrogen (TN) content changed during the composting process. The research was carried out with three variables mixtures of diaper wastes and vegetable wastes. Two control consist of 100% diaper wastes and 100% vegetables wastes. The Total weight of raw materials was 10 kg for each reactor. The composting process is carried out aerobically with a composting time of 60 days. The results showed that vegetable wastes have the potential to be used as a co-substrate for diaper wastes. The content of C-organic, VS and total nitrogen decreased. All of the parameters include C/N ratio meet the Indonesian Standard of compost.

Environmental factors play a role in increasing or decreasing the risk of metabolic syndrome (MetS) in adolescents. We analyzed the impact of physical activity (PA), dietary habits, and mental and socioeconomic status on MetS prevalence in 2143 (boys: 1113, girls: 1030, age: 13–18 years) Korean middle- and high-school students. Metabolically healthy obesity and metabolically unhealthy normal weight were also evaluated. MetS occurred in 215 participants (10.0%), and boys had a higher MetS rate than girls. There was no significant difference in alcohol consumption and smoking experience between individuals with and those without MetS. The odds ratio (OR) for high-school students was 1.33 (95%CI, 1.001–1.789, p = 0.043) times that of middle-school students. Depression, low aerobic PA, and high sedentary time increased the ORs to 1.64 (95%CI, 1.059–2.539, p = 0.020), 1.52 (95%CI, 1.092–2.203, p = 0.003), and 1.86 (95%CI, 1.342–2.587, p < 0.001), respectively. Higher energy intake and low weekly breakfast consumption frequency yielded ORs of 1.46 (95%CI, 1.046–2.555, p = 0.025) and 1.70 (95%CI, 1.244–2.339, p = 0.011), respectively. Strength training, stress, suicidal ideation, dining out frequency, and household income did not impact MetS prevalence. Despite obesity, MetS decreased by 29.7% with high aerobic PA and 37.9% with high weekly breakfast consumption frequency. In conclusion, MetS risk was higher for men, individuals with depression, and high-school students. Low aerobic activity, high calorie intake, and low weekly breakfast consumption frequency increased MetS risk. Despite obesity, high aerobic activity, low sedentary time, and breakfast consumption was associated with lower MetS risk.

Abstract Brewers’ spent grain (BSG) is the amplest by-product of the brewing process. The fresh BSG is currently used as low-cost cattle feed due to its microbiological instability and high perishability. While recent research looked at the effects of storage time and temperature on the characteristics of wet brewers grains (WBG) as ruminant feeds. Three storage temperatures (15, 20, and 25 °C) and periods (2, 4 and 6 days) were arranged in a 3 × 3 factorial design. Surface spoilage was not apparent at 15 °C throughout the storage periods. Deterioration was not also observed at 20 °C until the fourth day of storage where slight mold growth was apparent. Extensive mold growth was detected late in the sixth day at 20 °C and continued manifestations up until the last day of storage at 25 °C. Changes in major nutrients, DM losses, and yeast and mold colony count were significantly affected by the interaction of storage temperatures and durations (P