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11,045 results on '"A., Moralejo"'

151. Monte Carlo studies for the optimisation of the Cherenkov Telescope Array layout

Author: Acharyya, A., Agudo, I., Angüner, E. O., Alfaro, R., Alfaro, J., Alispach, C., Aloisio, R., Batista, R. Alves, Amans, J. -P., Amati, L., Amato, E., Ambrosi, G., Antonelli, L. A., Aramo, C., Armstrong, T., Arqueros, F., Arrabito, L., Asano, K., Ashkar, H., Balazs, C., Balbo, M., Balmaverde, B., Barai, P., Barbano, A., Barkov, M., de Almeida, U. Barres, Barrio, J. A., Bastieri, D., González, J. Becerra, Tjus, J. Becker, Bellizzi, L., Benbow, W., Bernardini, E., Bernardos, M. I., Bernlöhr, K., Berti, A., Berton, M., Bertucci, B., Beshley, V., Biasuzzi, B., Bigongiari, C., Bird, R., Bissaldi, E., Biteau, J., Blanch, O., Blazek, J., Boisson, C., Bonanno, G., Bonardi, A., Bonavolontà, C., Bonnoli, G., Bordas, P., Böttcher, M., Bregeon, J., Brill, A., Brown, A. M., Brügge, K., Brun, P., Bruno, P., Bulgarelli, A., Bulik, T., Burton, M., Burtovoi, A., Busetto, G., Cameron, R., Canestrari, R., Capalbi, M., Caproni, A., Capuzzo-Dolcetta, R., Caraveo, P., Caroff, S., Carosi, R., Casanova, S., Cascone, E., Cassol, F., Catalani, F., Catalano, O., Cauz, D., Cerruti, M., Chaty, S., Chen, A., Chernyakova, M., Chiaro, G., Cieślar, M., Colak, S. M., Conforti, V., Congiu, E., Contreras, J. L., Cortina, J., Costa, A., Costantini, H., Cotter, G., Cristofari, P., Cumani, P., Cusumano, G., D'Aì, A., D'Ammando, F., Dangeon, L., Da Vela, P., Dazzi, F., De Angelis, A., De Caprio, V., Anjos, R. de Cássia dos, De Frondat, F., Pino, E. M. de Gouveia Dal, De Lotto, B., De Martino, D., de Naurois, M., Wilhelmi, E. de Oña, de Palma, F., de Souza, V., Del Santo, M., Delgado, C., della Volpe, D., Di Girolamo, T., Di Pierro, F., Di Venere, L., Díaz, C., Diebold, S., Djannati-Ataï, A., Dmytriiev, A., Prester, D. Dominis, Donini, A., Dorner, D., Doro, M., Dournaux, J. -L., Ebr, J., Ekoume, T. R. N., Elsässer, D., Emery, G., Falceta-Goncalves, D., Fedorova, E., Fegan, S., Feng, Q., Ferrand, G., Fiandrini, E., Fiasson, A., Filipovic, M., Fioretti, V., Fiori, M., Flis, S., Fonseca, M. V., Fontaine, G., Coromina, L. Freixas, Fukami, S., Fukui, Y., Funk, S., Füßling, M., Gaggero, D., Galanti, G., López, R. J. Garcia, Garczarczyk, M., Gascon, D., Gasparetto, T., Gaug, M., Ghalumyan, A., Gianotti, F., Giavitto, G., Giglietto, N., Giordano, F., Giroletti, M., Gironnet, J., Glicenstein, J. -F., Gnatyk, R., Goldoni, P., González, J. M., González, M. M., Gourgouliatos, K. N., Grabarczyk, T., Granot, J., Green, D., Greenshaw, T., Grondin, M. -H., Gueta, O., Hadasch, D., Hassan, T., Hayashida, M., Heller, M., Hervet, O., Hinton, J., Hiroshima, N., Hnatyk, B., Hofmann, W., Horvath, P., Hrabovsky, M., Hrupec, D., Humensky, T. B., Hütten, M., Inada, T., Iocco, F., Ionica, M., Iori, M., Iwamura, Y., Jamrozy, M., Janecek, P., Jankowsky, D., Jean, P., Jouvin, L., Jurysek, J., Kaaret, P., Kadowaki, L. H. S., Karkar, S., Kerszberg, D., Khélifi, B., Kieda, D., Kimeswenger, S., Kluźniak, W., Knapp, J., Knödlseder, J., Kobayashi, Y., Koch, B., Kocot, J., Komin, N., Kong, A., Kowal, G., Krause, M., Kubo, H., Kushida, J., Kushwaha, P., La Parola, V., La Rosa, G., Arquillo, M. Lallena, Lang, R. G., Lapington, J., Blanc, O. Le, Lefaucheur, J., de Oliveira, M. A. Leigui, Lemoine-Goumard, M., Lenain, J. -P., Leto, G., Lico, R., Lindfors, E., Lohse, T., Lombardi, S., Longo, F., Lopez, A., López, M., Lopez-Oramas, A., López-Coto, R., Loporchio, S., Luque-Escamilla, P. L., Lyard, E., Maccarone, M. C., Mach, E., Maggio, C., Majumdar, P., Malaguti, G., Mallamaci, M., Mandat, D., Maneva, G., Manganaro, M., Mangano, S., Marculewicz, M., Mariotti, M., Martí, J., Martínez, M., Martínez, G., Martínez-Huerta, H., Masuda, S., Maxted, N., Mazin, D., Meunier, J. -L., Meyer, M., Micanovic, S., Millul, R., Minaya, I. A., Mitchell, A., Mizuno, T., Moderski, R., Mohrmann, L., Montaruli, T., Moralejo, A., Morcuende, D., Morlino, G., Morselli, A., Moulin, E., Mukherjee, R., Munar, P., Mundell, C., Murach, T., Nagai, A., Nagayoshi, T., Naito, T., Nakamori, T., Nemmen, R., Niemiec, J., Nieto, D., Rosillo, M. Nievas, Nikołajuk, M., Ninci, D., Nishijima, K., Noda, K., Nosek, D., Nöthe, M., Nozaki, S., Ohishi, M., Ohtani, Y., Okumura, A., Ong, R. A., Orienti, M., Orito, R., Ostrowski, M., Otte, N., Ou, Z., Oya, I., Pagliaro, A., Palatiello, M., Palatka, M., Paoletti, R., Paredes, J. M., Pareschi, G., Parmiggiani, N., Parsons, R. D., Patricelli, B., Pe'er, A., Pech, M., Del Campo, P. Peñil, Pérez-Romero, J., Perri, M., Persic, M., Petrucci, P. -O., Petruk, O., Pfrang, K., Piel, Q., Pietropaolo, E., Pohl, M., Polo, M., Poutanen, J., Prandini, E., Produit, N., Prokoph, H., Prouza, M., Przybilski, H., Pühlhofer, G., Punch, M., Queiroz, F., Quirrenbach, A., Rainò, S., Rando, R., Razzaque, S., Reimer, O., Renault-Tinacci, N., Renier, Y., Ribeiro, D., Ribó, M., Rico, J., Rieger, F., Rizi, V., Fernandez, G. Rodriguez, Rodriguez-Ramirez, J. C., Vázquez, J. J. Rodríguez, Romano, P., Romeo, G., Roncadelli, M., Rosado, J., Rowell, G., Rudak, B., Rugliancich, A., Rulten, C., Sadeh, I., Saha, L., Saito, T., Sakurai, S., Greus, F. Salesa, Sangiorgi, P., Sano, H., Santander, M., Santangelo, A., Santos-Lima, R., Sanuy, A., Satalecka, K., Saturni, F. G., Sawangwit, U., Schlenstedt, S., Schovanek, P., Schussler, F., Schwanke, U., Sciacca, E., Scuderi, S., Sedlaczek, K., Seglar-Arroyo, M., Sergijenko, O., Seweryn, K., Shalchi, A., Shellard, R. C., Siejkowski, H., Sillanpää, A., Sinha, A., Sironi, G., Sliusar, V., Slowikowska, A., Sol, H., Specovius, A., Spencer, S., Spengler, G., Stamerra, A., Stanič, S., Stawarz, Ł., Stefanik, S., Stolarczyk, T., Straumann, U., Suomijarvi, T., Świerk, P., Szepieniec, T., Tagliaferri, G., Tajima, H., Tam, T., Tavecchio, F., Taylor, L., Tejedor, L. A., Temnikov, P., Terzic, T., Testa, V., Tibaldo, L., Peixoto, C. J. Todero, Tokanai, F., Tomankova, L., Tonev, D., Torres, D. F., Tosti, G., Tosti, L., Tothill, N., Toussenel, F., Tovmassian, G., Travnicek, P., Trichard, C., Umana, G., Vagelli, V., Valentino, M., Vallage, B., Vallania, P., Valore, L., Vandenbroucke, J., Varner, G. S., Vasileiadis, G., Vassiliev, V., Acosta, M. Vázquez, Vecchi, M., Vercellone, S., Vergani, S., Vettolani, G. P., Viana, A., Vigorito, C. F., Vink, J., Vitale, V., Voelk, H., Vollhardt, A., Vorobiov, S., Wagner, S. J., Walter, R., Werner, F., White, R., Wierzcholska, A., Will, M., Williams, D. A., Wischnewski, R., Yang, L., Yoshida, T., Yoshikoshi, T., Zacharias, M., Zampieri, L., Zavrtanik, M., Zavrtanik, D., Zdziarski, A. A., Zech, A., Zechlin, H., Zenin, A., Zhdanov, V. I., Zimmer, S., and Zorn, J.
Subjects: Astrophysics - Instrumentation and Methods for Astrophysics
Abstract: The Cherenkov Telescope Array (CTA) is the major next-generation observatory for ground-based very-high-energy gamma-ray astronomy. It will improve the sensitivity of current ground-based instruments by a factor of five to twenty, depending on the energy, greatly improving both their angular and energy resolutions over four decades in energy (from 20 GeV to 300 TeV). This achievement will be possible by using tens of imaging Cherenkov telescopes of three successive sizes. They will be arranged into two arrays, one per hemisphere, located on the La Palma island (Spain) and in Paranal (Chile). We present here the optimised and final telescope arrays for both CTA sites, as well as their foreseen performance, resulting from the analysis of three different large-scale Monte Carlo productions., Comment: 48 pages, 16 figures, accepted for publication in Astroparticle Physics
Published: 2019
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152. Measurement of the Extragalactic Background Light using MAGIC and Fermi-LAT gamma-ray observations of blazars up to z = 1

Author: MAGIC collaboration, Acciari, V. A., Ansoldi, S., Antonelli, L. A., Engels, A. Arbet, Baack, D., Babić, A., Banerjee, B., de Almeida, U. Barres, Barrio, J. A., González, J. Becerra, Bednarek, W., Bellizzi, L., Bernardini, E., Berti, A., Besenrieder, J., Bhattacharyya, W., Bigongiari, C., Biland, A., Blanch, O., Bonnoli, G., Busetto, G., Carosi, R., Ceribella, G., Chai, Y., Cikota, S., Çolak, S. M., Colin, U., Colombo, E., Contreras, J. L., Cortina, J., Covino, S., D'Elia, V., Da Vela, P., Dazzi, F., De Angelis, A., De Lotto, B., Delfino, M., Delgado, J., Di Pierro, F., Espiñeira, E. Do Souto, Domínguez, A., Prester, D. Dominis, Dorner, D., Doro, M., Elsaesser, D., Ramazani, V. Fallah, Fattorini, A., Fernández-Barral, A., Ferrara, G., Fidalgo, D., Foffano, L., Fonseca, M. V., Font, L., Fruck, C., Galindo, D., Gallozzi, S., López, R. J. García, Garczarczyk, M., Gasparyan, S., Gaug, M., Godinović, N., Green, D., Guberman, D., Hadasch, D., Hahn, A., Hassan, T., Herrera, J., Hoang, J., Hrupec, D., Inoue, S., Ishio, K., Iwamura, Y., Kubo, H., Kushida, J., Lamastra, A., Lelas, D., Leone, F., Lindfors, E., Lombardi, S., Longo, F., López, M., López-Coto, R., López-Oramas, A., Fraga, B. Machado de Oliveira, Maggio, C., Majumdar, P., Makariev, M., Mallamaci, M., Maneva, G., Manganaro, M., Mannheim, K., Maraschi, L., Mariotti, M., Martínez, M., Masuda, S., Mazin, D., Mićanović, S., Miceli, D., Minev, M., Miranda, J. M., Mirzoyan, R., Molina, E., Moralejo, A., Morcuende, D., Moreno, V., Moretti, E., Munar-Adrover, P., Neustroev, V., Niedzwiecki, A., Rosillo, M. Nievas, Nigro, C., Nilsson, K., Ninci, D., Nishijima, K., Noda, K., Nogués, L., Nöthe, M., Paiano, S., Palacio, J., Palatiello, M., Paneque, D., Paoletti, R., Paredes, J. M., Peñil, P., Peresano, M., Persic, M., Moroni, P. G. Prada, Prandini, E., Puljak, I., Rhode, W., Ribó, M., Rico, J., Righi, C., Rugliancich, A., Saha, L., Sahakyan, N., Saito, T., Satalecka, K., Schweizer, T., Sitarek, J., Šnidarić, I., Sobczynska, D., Somero, A., Stamerra, A., Strom, D., Strzys, M., Surić, T., Tavecchio, F., Temnikov, P., Terzić, T., Teshima, M., Torres-Alba, N., Tsujimoto, S., van Scherpenberg, J., Vanzo, G., Acosta, M. Vázquez, Vovk, I., Will, M., and Zarić, D.
Subjects: Astrophysics - High Energy Astrophysical Phenomena
Abstract: We present a measurement of the extragalactic background light (EBL) based on a joint likelihood analysis of 32 gamma-ray spectra for 12 blazars in the redshift range z = 0.03 to 0.944, obtained by the MAGIC telescopes and Fermi-LAT. The EBL is the part of the diffuse extragalactic radiation spanning the ultraviolet, visible and infrared bands. Major contributors to the EBL are the light emitted by stars through the history of the universe, and the fraction of it which was absorbed by dust in galaxies and re-emitted at longer wavelengths. The EBL can be studied indirectly through its effect on very-high energy photons that are emitted by cosmic sources and absorbed via photon-photon interactions during their propagation across cosmological distances. We obtain estimates of the EBL density in good agreement with state-of-the-art models of the EBL production and evolution. The 1-sigma upper bounds, including systematic uncertainties, are between 13% and 23% above the nominal EBL density in the models. No anomaly in the expected transparency of the universe to gamma rays is observed in any range of optical depth.We also perform a wavelength-resolved EBL determination, which results in a hint of an excess of EBL in the 0.18 - 0.62 $\mu$m range relative to the studied models, yet compatible with them within systematics., Comment: Accepted by MNRAS
Published: 2019
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153. EN TORNO AL BELLUM HISPANIENSE Y LAS GLANDES INSCRIPTAE DE HISPANIA. UN NUEVO PROYECTIL CON INSCRIPCIÓN CESARIANA PROCEDENTE DE MONTILLA (CÓRDOBA)

Author: Moralejo Ordax, Javier, Morena López, José Antonio, Moreno Rosa, Antonio, and Robles Moreno, Jesús
Published: 2023

154. Circular 3/ 2022, de 30 de marzo, del Banco de España, por la que se modifican la Circular 2/2016, de 2 de febrero; la Circular 2/2014, de 31 de enero, y la Circular 5/2021, de 27 de junio [BOE-A-2022-5524]

Author: Ignacio Moralejo Menéndez
Subjects: Law in general. Comparative and uniform law. Jurisprudence, K1-7720, Political science (General), JA1-92
Published: 2023

155. Reseña de Una reciente edición de las obras menores de Tácito: José Luis Moralejo, Tácito, Vida de Julio Agrícola. Del origen y situación de los germanos. Diálogo sobre los oradores. Prólogos, texto revisado, traducciones, notas e índices, Madrid: Consejo Superior de Investigaciones Científicas

Author: Vidal, José Luis and Fábrega Salis, Pere
Published: 2018
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156. Learning pathways: Levelling, scaffolding & mapping curriculum

Author: Reekie, Manuela, de Bosch Kemper, Nicole, Epp, Sheila, Denison, Jacqueline, Willson, Melanie, and Moralejo, Lisa
Published: 2023
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157. Tácito. Historias. Ed. de J. L. Moralejo Álvarez. Madrid, Akal Clásica, 1990, 335 pp.

Author: Montero, Santiago and Montero, Santiago
Abstract: Sin resumen
Published: 1991

158. Rafael GONZÁLEZ MORALEJO, El Vaticano II en Taquigrafía. La historia de la «Gaudium et spes», BAC, Madrid 2000, 224 pp., 13,7 x 20,5, ISBN 84-7914- 470-X.

Author: Lorda, Juan Luis, primary
Published: 2017
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159. Answers linked to Gould DJ, Creedon S, Jeanes A, Drey NS, Chudleigh J, Moralejo D. Impact of observing hand hygiene in practice and research: a methodological reconsideration. J Hosp Infect 2017;95:169–174

Published: 2017
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160. Questions linked to Gould DJ, Creedon S, Jeanes A, Drey NS, Chudleigh J, Moralejo D. Impact of observing hand hygiene in practice and research: a methodological reconsideration. J Hosp Infect 2017;95:169–174

Published: 2017
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161. Deceased donor kidney procurement: Systematic review of the surgical technique

Author: Polanco Pujol, L., Caño Velasco, J., González García, J., Herranz Amo, F., Lledó García, E., Bueno Chomón, G., Mayor de Castro, J., Aragón Chamizo, J., Arnal Chacón, G., Moralejo Gárate, M., Subirá Ríos, D., Diez Cordero, J.M., Durán Merino, R., and Hernández Fernández, C.
Published: 2023
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162. Extracción renal en donante cadáver: revisión sistemática de la técnica quirúrgica

Author: Polanco Pujol, L., Velasco, J. Caño, González García, J., Herranz Amo, F., Lledó García, E., Chomón, G. Bueno, Castro, J. Mayor de, Chamizo, J. Aragón, Chacón, G. Arnal, Gárate, M. Moralejo, Ríos, D. Subirá, Diez Cordero, J.M., Durán Merino, R., and Hernández Fernández, C.
Published: 2023
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163. Effectiveness of a foot self-management intervention that utilized commercially available infrared thermometers: Mixed methods research incorporating a pilot RCT

Author: Stevens, Kathleen, Moralejo, Donna, Ersser, Steven, and MacLean, Cathy
Published: 2023
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164. Global predictions for the risk of establishment of Pierce’s disease of grapevines

Author: Alex Giménez-Romero, Javier Galván, Marina Montesinos, Joan Bauzà, Martin Godefroid, Alberto Fereres, José J. Ramasco, Manuel A. Matías, and Eduardo Moralejo
Subjects: Biology (General), QH301-705.5
Abstract: A temperature-driven dynamic epidemiological model provides insights into the risk for Pierce’s disease in grapevine.
Published: 2022
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165. Eleonora di Toledo e l’invenzione della corte dei Medici a Firenze. Florencia: Tesoro dei Granduchi, Palazzo Pitti, 6-II-2023 a 14-V-2023

Author: Macarena Moralejo Ortega
Subjects: Arts in general, NX1-820
Published: 2023
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166. Evaluation of Incremental Validity of Casper in Predicting Program and National Licensure Performance of Undergraduate Nursing Students: Protocol for a Mixed Methods Study

Author: Kathleen Stevens, Donna Moralejo, and Renee Crossman
Subjects: Medicine, Computer applications to medicine. Medical informatics, R858-859.7
Abstract: BackgroundAcademic success has been the primary criterion for admission to many nursing programs. However, academic success as an admission criterion may have limited predictive value for success in noncognitive skills. Adding situational judgment tests, such as Casper, to admissions procedures may be one strategy to strengthen decisions and address the limited predictive value of academic admission criteria. In 2021, admissions processes were modified to include Casper based on concerns identified with noncognitive skills. ObjectiveThis study aims to (1) assess the incremental validity of Casper scores in predicting nursing student performance at years 1, 2, 3, and 4 and on the National Council Licensing Examination (NCLEX) performance; and (2) examine faculty members’ perceptions of student performance and influences related to communication, professionalism, empathy, and problem-solving. MethodsWe will use a multistage evaluation mixed methods design with 5 phases. At the end of each year, students will complete questionnaires related to empathy and professionalism and have their performance assessed for communication and problem-solving in psychomotor laboratory sessions. The final phase will assess graduate performance on the NCLEX. Each phase also includes qualitative data collection (ie, focus groups with faculty members). The goal of the focus groups is to help explain the quantitative findings (explanatory phase) as well as inform data collection (eg, focus group questions) in the subsequent phase (exploratory sequence). All students enrolled in the first year of the nursing program in 2021 were asked to participate (n=290). Faculty will be asked to participate in the focus groups at the end of each year of the program. Hierarchical multiple regression will be conducted for each outcome of interest (eg, communication, professionalism, empathy, and problem-solving) to determine the extent to which scores on Casper with admission grades, compared to admission grades alone, predict nursing student performance at years 1-4 of the program and success on the national exam. Thematic analysis of focus group transcripts will be conducted using interpretive description. The quantitative and qualitative data will be integrated after each phase is complete and at the end of the study. ResultsThis study was funded in September 2021, and data collection began in March 2022. Year 1 data collection and analysis are complete. Year 2 data collection is complete, and data analysis is in progress. ConclusionsAt the end of the study, we will provide the results of a comprehensive analysis to determine the extent to which the addition of scores on Casper compared to admission grades alone predicts nursing student performance at years 1-4 of the program and on the NCLEX exam. International Registered Report Identifier (IRRID)RR1-10.2196/48672
Published: 2023
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167. PB2701: SAFETY OF 30 MINUTES INFUSION OF RITUXIMAB BIOSIMILAR. A COHORT STUDY.

Author: Laida Cuevas Palomares, Ernesto Pérez, Ariane Unamunzaga Cilaurren, Xabier Gutierrez Lopez De Ocariz, Buenaventura Buendia Ureña, Carmen Molinillo Fernández, Begoña Benito Ibarrondo, Ana Cordero Osua, Beatriz Benitez Delgado, Miguel Andrés Moralejo, Juan García Albás, and Jose Guinea de Castro
Subjects: Diseases of the blood and blood-forming organs, RC633-647.5
Published: 2023
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168. Deep observations of the globular cluster M15 with the MAGIC telescopes

Author: MAGIC Collaboration, Acciari, V. A., Ansoldi, S., Antonelli, L. A., Engels, A. Arbet, Baack, D., Babić, A., Banerjee, B., de Almeida, U. Barres, Barrio, J. A., González, J. Becerra, Bednarek, W., Bernardini, E., Berti, A., Besenrieder, J., Bhattacharyya, W., Bigongiari, C., Biland, A., Blanch, O., Bonnoli, G., Busetto, G., Carosi, R., Ceribella, G., Cikota, S., Colak, S. M., Colin, P., Colombo, E., Contreras, J. L., Cortina, J., Covino, S., D'Elia, V., Da Vela, P., Dazzi, F., De Angelis, A., De Lotto, B., Delfino, M., Delgado, J., Di Pierro, F., Espiñera, E. Do Souto, Domínguez, A., Prester, D. Dominis, Dorner, D., Doro, M., Einecke, S., Elsaesser, D., Ramazani, V. Fallah, Fattorini, A., Fernández-Barral, A., Ferrara, G., Fidalgo, D., Foffano, L., Fonseca, M. V., Font, L., Fruck, C., Galindo, D., Gallozzi, S., López, R. J. García, Garczarczyk, M., Gasparyan, S., Gaug, M., Giammaria, P., Godinović, N., Green, D., Guberman, D., Hadasch, D., Hahn, A., Herrera, J., Hoang, J., Hrupec, D., Inoue, S., Ishio, K., Iwamura, Y., Kubo, H., Kushida, J., Kuveždić, D., Lamastra, A., Lelas, D., Leone, F., Lindfors, E., Lombardi, S., Longo, F., López, M., López-Oramas, A., Fraga, B. Machado de Oliveira, Maggio, C., Majumdar, P., Makariev, M., Mallamaci, M., Maneva, G., Manganaro, M., Mannheim, K., Maraschi, L., Mariotti, M., Martínez, M., Masuda, S., Mazin, D., Minev, M., Miranda, J. M., Mirzoyan, R., Molina, E., Moralejo, A., Moreno, V., Moretti, E., Munar-Adrover, P., Neustroev, V., Niedzwiecki, A., Rosillo, M. Nievas, Nigro, C., Nilsson, K., Ninci, D., Nishijima, K., Noda, K., Nogués, L., Nöthe, M., Paiano, S., Palacio, J., Paneque, D., Paoletti, R., Paredes, J. M., Pedaletti, G., Peñil, P., Peresano, M., Persic, M., Moroni, P. G. Prada, Prandini, E., Puljak, I., Garcia, J. R., Rhode, W., Ribó, M., Rico, J., Righi, C., Rugliancich, A., Saha, L., Sahakyan, N., Saito, T., Satalecka, K., Schweizer, T., Sitarek, J., Šnidarić, I., Sobczynska, D., Somero, A., Stamerra, A., Strzys, M., Surić, T., Tavecchio, F., Temnikov, P., Terzić, T., Teshima, M., Torres-Albà, N., Tsujimoto, S., van Scherpenberg, J., Vanzo, G., Acosta, M. Vazquez, Vovk, I., Will, M., and Zarić, D.
Subjects: Astrophysics - High Energy Astrophysical Phenomena
Abstract: A population of globular clusters (GCs) has been recently established by the Fermi-LAT telescope as a new class of GeV $\gamma$-ray sources. Leptons accelerated to TeV energies, in the inner magnetospheres of MSPs or in their wind regions, should produce $\gamma$-rays through the inverse Compton scattering in the dense radiation field from the huge population of stars. We have conducted deep observations of the globular cluster M15 with the MAGIC telescopes and used 165 hrs in order to search for $\gamma$-ray emission. A strong upper limit on the TeV $\gamma$-ray flux $<3.2\times 10^{-13}\mathrm{cm^{-2}s^{-1}}$ above 300 GeV ($<0.26\%$ of the Crab nebula flux) has been obtained. We interpret this limit as a constraint on the efficiency of the acceleration of leptons in the magnetospheres of the MSPs. We constrain the injection rate of relativistic leptons, $\eta_{\rm e}$, from the MSPs magnetospheres and their surrounding. We conclude that $\eta_{\rm e}$ must be lower than expected from the modelling of high energy processes in MSP inner magnetospheres. For leptons accelerated with the power law spectrum in the MSP wind regions, $\eta_{\rm e}$ is constrained to be much lower than derived for the wind regions around classical pulsars. These constraints are valid for the expected range of magnetic field strengths within the GC and for the range of likely energies of leptons injected from the inner magnetospheres, provided that the leptons are not removed from the globular cluster very efficiently due to advection process. We discuss consequences of these constraints for the models of radiation processes around millisecond pulsars., Comment: 11 pages, 7 figures, accepted for publication in MNRAS
Published: 2019
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169. MAGIC and Fermi-LAT gamma-ray results on unassociated HAWC sources

Author: Ahnen, M. L., Ansoldi, S., Antonelli, L. A., Arcaro, C., Baack, D., Babić, A., Banerjee, B., Bangale, P., de Almeida, U. Barres, Barrio, J. A., González, J. Becerra, Bednarek, W., Bernardini, E., Berse, R. Ch., Berti, A., Bhattacharyya, W., Biland, A., Blanch, O., Bonnoli, G., Carosi, R., Carosi, A., Ceribella, G., Chatterjee, A., Colak, S. M., Colin, P., Colombo, E., Contreras, J. L., Cortina, J., Covino, S., Cumani, P., Da Vela, P., Dazzi, F., De Angelis, A., De Lotto, B., Delfino, M., Delgado, J., Di Pierro, F., Domínguez, A., Prester, D. Dominis, Dorner, D., Doro, M., Einecke, S., Elsaesser, D., Ramazani, V. Fallah, Fernández-Barral, A., Fidalgo, D., Fonseca, M. V., Font, L., Fruck, C., Galindo, D., López, R. J. García, Garczarczyk, M., Gaug, M., Giammaria, P., Godinović, N., Gora, D., Guberman, D., Hadasch, D., Hahn, A., Hassan, T., Hayashida, M., Herrera, J., Hose, J., Hrupec, D., Ishio, K., Konno, Y., Kubo, H., Kushida, J., Kuveždić, D., Lelas, D., Lindfors, E., Lombardi, S., Longo, F., López, M., Maggio, C., Majumdar, P., Makariev, M., Maneva, G., Manganaro, M., Mannheim, K., Maraschi, L., Mariotti, M., Martínez, M., Masuda, S., Mazin, D., Mielke, K., Minev, M., Miranda, J. M., Mirzoyan, R., Moralejo, A., Moreno, V., Moretti, E., Nagayoshi, T., Neustroev, V., Niedzwiecki, A., Rosillo, M. Nievas, Nigro, C., Nilsson, K., Ninci, D., Nishijima, K., Noda, K., Nogués, L., Paiano, S., Palacio, J., Paneque, D., Paoletti, R., Paredes, J. M., Pedaletti, G., Peresano, M., Persic, M., Moroni, P. G. Prada, Prandini, E., Puljak, I., Garcia, J. R., Reichardt, I., Rhode, W., Ribó, M., Rico, J., Righi, C., Rugliancich, A., Saito, T., Satalecka, K., Schweizer, T., Sitarek, J., Šnidarić, I., Sobczynska, D., Stamerra, A., Strzys, M., Surić, T., Takahashi, M., Takalo, L., Tavecchio, F., Temnikov, P., Terzić, T., Teshima, M., Torres-Albà, N., Treves, A., Tsujimoto, S., Vanzo, G., Acosta, M. Vazquez, Vovk, I., Ward, J. E., Will, M., Zarić, D., Albert, A., Alfaro, R., Alvarez, C., Arceo, R., Arteaga-Velázquez, J. C., Rojas, D. Avila, Solares, H. A. Ayala, Becerril, A., Belmont-Moreno, E., BenZvi, S. Y., Bernal, A., Braun, J., Caballero-Mora, K. S., Capistrán, T., Carramiñana, A., Casanova, S., Castillo, M., Cotti, U., Cotzomi, J., de León, S. Coutiño, De León, C., De la Fuente, E., Hernandez, R. Diaz, Dichiara, S., Dingus, B. L., DuVernois, M. A., Díaz-Vélez, J. C., Ellsworth, R. W., Engel, K., Enriquez-Rivera, O., Fiorino, D. W., Fleischhack, H., Fraija, N., García-González, J. A., Garfias, F., González-Muñoz, A., González, M. M., Goodman, J. A., Hampel-Arias, Z., Harding, J. P., Hernandez, S., Hueyotl-Zahuantitla, F., Hui, C. M., Hüntemeyer, P., Iriarte, A., Jardin-Blicq, A., Joshi, V., Kaufmann, S., Lara, A., Lauer, R. J., Lee, W. H., Lennarz, D., Vargas, H. León, Linnemann, J. T., Longinotti, A. L., Luis-Raya, G., Luna-García, R., López-Coto, R., Malone, K., Marinelli, S. S., Martinez, O., Martinez-Castellanos, I., Martínez-Castro, J., Martínez-Huerta, H., Matthews, J. A., Miranda-Romagnoli, P., Moreno, E., Mostafá, M., Nayerhoda, A., Nellen, L., Newbold, M., Nisa, M. U., Noriega-Papaqui, R., Pelayo, R., Pretz, J., Pérez-Pérez, E. G., Ren, Z., Rho, C. D., Rivière, C., Rosa-González, D., Rosenberg, M., Ruiz-Velasco, E., Greus, F. Salesa, Sandoval, A., Schneider, M., Arroyo, M. Seglar, Sinnis, G., Smith, A. J., Springer, R. W., Surajbali, P., Taboada, I., Tibolla, O., Tollefson, K., Torres, I., Ukwatta, T. N., Vianello, G., Villaseñor, L., Werner, F., Westerhoff, S., Wood, J., Yapici, T., Yodh, G., Zepeda, A., Zhou, H., Álvarez, J. D., Ajello, M., Baldini, L., Barbiellini, G., Berenji, B., Bissaldi, E., Blandford, R. D., Bonino, R., Bottacini, E., Brandt, T. J., Bregeon, J., Bruel, P., Cameron, R. A., Caputo, R., Caraveo, P. A., Castro, D., Cavazzuti, E., Chiaro, G., Ciprini, S., Costantin, D., D'Ammando, F., de Palma, F., Desai, A., Di Lalla, N., Di Mauro, M., Di Venere, L., Favuzzi, C., Fukazawa, Y., Funk, S., Fusco, P., Gargano, F., Gasparrini, D., Giglietto, N., Giordano, F., Giroletti, M., Glanzman, T., Green, D., Grenier, I. A., Guiriec, S., Harding, A. K., Hays, E., Hewitt, J. W., Horan, D., Jóhannesson, G., Kuss, M., Larsson, S., Liodakis, I., Loparco, F., Lubrano, P., Magill, J. D., Maldera, S., Manfreda, A., Mazziotta, M. N., Mereu, I., Michelson, P. F., Mizuno, T., Monzani, M. E., Morselli, A., Moskalenko, I. V., Negro, M., Nuss, E., Omodei, N., Orienti, M., Orlando, E., Ormes, J. F., Palatiello, M., Paliya, V. S., Pesce-Rollins, M., Petrosian, V., Piron, F., Porter, T. A., Principe, G., Rainò, S., Rani, B., Razzano, M., Razzaque, S., Reimer, A., Reimer, O., Sgrò, C., Siskind, E. J., Spandre, G., Spinelli, P., Tajima, H., Thayer, J. B., Thompson, D. J., Torres, D. F., Torresi, E., Troja, E., Valverde, J., Wood, K., and Yassine, M.
Subjects: Astrophysics - High Energy Astrophysical Phenomena
Abstract: The HAWC Collaboration released the 2HWC catalog of TeV sources, in which 19 show no association with any known high-energy (HE; E > 10 GeV) or very-high-energy (VHE; E > 300 GeV) sources. This catalog motivated follow-up studies by both the MAGIC and Fermi-LAT observatories with the aim of investigating gamma-ray emission over a broad energy band. In this paper, we report the results from the first joint work between HAWC, MAGIC and Fermi-LAT on three unassociated HAWC sources: 2HWC J2006+341, 2HWC J1907+084* and 2HWC J1852+013*. Although no significant detection was found in the HE and VHE regimes, this investigation shows that a minimum 1 degree extension (at 95% confidence level) and harder spectrum in the GeV than the one extrapolated from HAWC results are required in the case of 2HWC J1852+013*, while a simply minimum extension of 0.16 degrees (at 95% confidence level) can already explain the scenario proposed by HAWC for the remaining sources. Moreover, the hypothesis that these sources are pulsar wind nebulae is also investigated in detail., Comment: 12 pages, 3 figures. Accepted for publication in MNRAS
Published: 2019
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170. A Fast Very High Energy $\gamma$-ray Flare from BL Lacertae during a Period of Multiwavelength activity in June 2015

Author: MAGIC Collaboration, Acciari, V. A., Ansoldi, S., Antonelli, L. A., Engels, A. Arbet, Baack, D., Babić, A., Banerjee, B., Bangale, P., de Almeida, U. Barres, Barrio, J. A., González, J. Becerra, Bednarek, W., Bernardini, E., Berti, A., Besenrieder, J., Bhattacharyya, W., Bigongiari, C., Biland, A., Blanch, O., Bonnoli, G., Carosi, R., Ceribella, G., Cikota, S., Colak, S. M., Colin, P., Colombo, E., Contreras, J. L., Cortina, J., Covino, S., D'Elia, V., Da Vela, P., Dazzi, F., De Angelis, A., De Lotto, B., Delfino, M., Delgado, J., Di Pierro, F., Espiñera, E. Do Souto, Domínguez, A., Prester, D. Dominis, Dorner, D., Doro, M., Einecke, S., Elsaesser, D., Ramazani, V. Fallah, Fattorini, A., Fernández-Barral, A., Ferrara, G., Fidalgo, D., Foffano, L., Fonseca, M. V., Font, L., Fruck, C., Galindo, D., Gallozzi, S., López, R. J. García, Garczarczyk, M., Gaug, M., Giammaria, P., Godinović, N., Guberman, D., Hadasch, D., Hahn, A., Hassan, T., Herrera, J., Hoang, J., Hrupec, D., Inoue, S., Ishio, K., Iwamura, Y., Kubo, H., Kushida, J., Kuveždić, D., Lamastra, A., Lelas, D., Leone, F., Lindfors, E., Lombardi, S., Longo, F., López, M., López-Oramas, A., Maggio, C., Majumdar, P., Makariev, M., Maneva, G., Manganaro, M., Mannheim, K., Maraschi, L., Mariotti, M., Martínez, M., Masuda, S., Mazin, D., Minev, M., Miranda, J. M., Mirzoyan, R., Molina, E., Moralejo, A., Moreno, V., Moretti, E., Munar-Adrover, P., Neustroev, V., Niedzwiecki, A., Rosillo, M. Nievas, Nigro, C., Nilsson, K., Ninci, D., Nishijima, K., Noda, K., Nogués, L., Nöthe, M., Paiano, S., Palacio, J., Paneque, D., Paoletti, R., Paredes, J. M., Pedaletti, G., Peñil, P., Peresano, M., Persic, M., Moroni, P. G. Prada, Prandini, E., Puljak, I., Garcia, J. R., Rhode, W., Ribó, M., Rico, J., Righi, C., Rugliancich, A., Saha, L., Saito, T., Satalecka, K., Schweizer, T., Sitarek, J., Šnidarić, I., Sobczynska, D., Somero, A., Stamerra, A., Strzys, M., Surić, T., Tavecchio, F., Temnikov, P., Terzić, T., Teshima, M., Torres-Albà, N., Tsujimoto, S., van Scherpenberg, J., Vanzo, G., Acosta, M. Vazquez, Vovk, I., Will, M., Zarić, D., D'Ammando, F., Hada, K., Jorstad, S., Marscher, A. P., Mobeen, M. Z., Larionov, V. M., Borman, G. A., Grishina, T. S., Kopatskaya, E. N., Morozova, D. A., Nikiforova, A. A., Lähteenmäki, A., Tornikoski, M., and Agudo, I.
Subjects: Astrophysics - High Energy Astrophysical Phenomena
Abstract: The mechanisms producing fast variability of the $\gamma$-ray emission in active galactic nuclei are under debate. The MAGIC telescopes detected a fast very high energy (VHE, E$>100$ GeV) $\gamma$-ray flare from BL Lacertae on 2015 June 15. The flare had a maximum flux of $(1.5\pm 0.3)\times 10^{-10}$ photons cm$^{-2}$ s$^{-1}$ and halving time of $26\pm8$ minutes. The MAGIC observations were triggered by a high state in the optical and high energy (HE, E$>100$ MeV) $\gamma$-ray bands. In this paper we present the MAGIC VHE $\gamma$-ray data together with multiwavelength data from radio, optical, X-rays, and HE $\gamma$ rays from 2015 May 1 to July 31. Well-sampled multiwavelength data allow us to study the variability in detail and compare it to the other epochs when fast VHE $\gamma$-ray flares have been detected from this source. Interestingly, we find that the behaviour in radio, optical, X-rays and HE $\gamma$-rays is very similar to two other observed VHE $\gamma$-ray flares. In particular, also during this flare there was an indication of rotation of the optical polarization angle and of activity at the 43\,GHz core. These repeating patterns indicate a connection between the three events. We also test modelling of the spectral energy distribution, based on constraints from the light curves and VLBA observations, with two different geometrical setups of two-zone inverse Compton models. In addition we model the $\gamma$-ray data with the star-jet interaction model. We find that all of the tested emission models are compatible with the fast VHE $\gamma$-ray flare, but all have some tension with the multiwavelength observations., Comment: Accepted to Astronomy & Astrophysics
Published: 2019
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171. Development of an immune-nutritional prognostic index in patients with muscle-infiltrating bladder cancer candidates for radical cystectomy

Author: Moreno-Cortés, J.C., Herranz-Amo, F., Bataller-Monfort, V., Esteban-Labrador, L., Quintana-Álvarez, R., Subirá-Rios, D., Moralejo-Garate, M., and Hernández-Fernández, C.
Published: 2023
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172. Elaboración de un índice pronóstico inmunonutricional en pacientes con cáncer de vejiga músculo-infiltrante candidatos a cistectomía radical

Author: Moreno-Cortés, J.C., Herranz-Amo, F., Bataller-Monfort, V., Esteban-Labrador, L., Quintana-Álvarez, R., Subirá-Rios, D., Moralejo-Garate, M., and Hernández-Fernández, C.
Published: 2023
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173. Discovery of TeV $\gamma$-ray emission from the neighbourhood of the supernova remnant G24.7+0.6 by MAGIC

Author: MAGIC Collaboration, Acciari, V. A., Ansoldi, S., Antonelli, L. A., Engels, A. Arbet, Arcaro, C., Baack, D., Babić, A., Banerjee, B., Bangale, P., de Almeida, U. Barres, Barrio, J. A., González, J. Becerra, Bednarek, W., Bernardini, E., Berti, A., Besenrieder, J., Bhattacharyya, W., Bigongiari, C., Biland, A., Blanch, O., Bonnoli, G., Carosi, R., Ceribella, G., Chatterjee, A., Colak, S. M., Colin, P., Colombo, E., Contreras, J. L., Cortina, J., Covino, S., Cumani, P., D'Elia, V., Da Vela, P., Dazzi, F., De Angelis, A., De Lotto, B., Delfino, M., Delgado, J., Di Pierro, F., Domínguez, A., Prester, D. Dominis, Dorner, D., Doro, M., Einecke, S., Elsaesser, D., Ramazani, V. Fallah, Fattorini, A., Fernández-Barral, A., Ferrara, G., Fidalgo, D., Foffano, L., Fonseca, M. V., Font, L., Fruck, C., Galindo, D., Gallozzi, S., López, R. J. García, Garczarczyk, M., Gaug, M., Giammaria, P., Godinović, N., Guberman, D., Hadasch, D., Hahn, A., Hassan, T., Herrera, J., Hoang, J., Hrupec, D., Inoue, S., Ishio, K., Iwamura, Y., Kubo, H., Kushida, J., Kuveždić, D., Lamastra, A., Lelas, D., Leone, F., Lindfors, E., Lombardi, S., Longo, F., López, M., López-Oramas, A., Maggio, C., Majumdar, P., Makariev, M., Maneva, G., Manganaro, M., Mannheim, K., Maraschi, L., Mariotti, M., Martínez, M., Masuda, S., Mazin, D., Minev, M., Miranda, J. M., Mirzoyan, R., Molina, E., Moralejo, A., Moreno, V., Moretti, E., Neustroev, V., Niedzwiecki, A., Rosillo, M. Nievas, Nigro, C., Nilsson, K., Ninci, D., Nishijima, K., Noda, K., Nogués, L., Paiano, S., Palacio, J., Paneque, D., Paoletti, R., Paredes, J. M., Pedaletti, G., Peñil, P., Peresano, M., Persic, M., Moroni, P. G. Prada, Prandini, E., Puljak, I., Garcia, J. R., Rhode, W., Ribó, M., Rico, J., Righi, C., Rugliancich, A., Saha, L., Saito, T., Satalecka, K., Schweizer, T., Sitarek, J., Šnidarić, I., Sobczynska, D., Somero, A., Stamerra, A., Strzys, M., Surić, T., Tavecchio, F., Temnikov, P., Terzić, T., Teshima, M., Torres-Albà, N., Tsujimoto, S., Vanzo, G., Acosta, M. Vazquez, Vovk, I., Ward, J. E., Will, M., Zarić, D., Wilhelmi, E. de Oña, Torres, D. F., and Zanin, R.
Subjects: Astrophysics - High Energy Astrophysical Phenomena
Abstract: SNR G24.7+0.6 is a 9.5 kyrs radio and $\gamma$-ray supernova remnant evolving in a dense medium. In the GeV regime, SNR G24.7+0.6 (3FHL\,J1834.1--0706e/FGES\,J1834.1--0706) shows a hard spectral index ($\Gamma$$\sim$2) up to $200$\,GeV, which makes it a good candidate to be observed with Cherenkov telescopes such as MAGIC. We observed the field of view of \snr\ with the MAGIC telescopes for a total of 31 hours. We detect very high energy $\gamma$-ray emission from an extended source located 0.34\degr\ away from the center of the radio SNR. The new source, named \mgc\ is detected up to 5\,TeV, and its spectrum is well-represented by a power-law function with spectral index of $2.74 \pm 0.08$. The complexity of the region makes the identification of the origin of the very-high energy emission difficult, however the spectral agreement with the LAT source and overlapping position at less than 1.5$\sigma$ point to a common origin. We analysed 8 years of \fermi-LAT data to extend the spectrum of the source down to 60\,MeV. \fermi-LAT and MAGIC spectra overlap within errors and the global broad band spectrum is described by a power-law with exponential cutoff at $1.9\pm0.5$\,TeV. The detected $\gamma$-ray emission can be interpreted as the results of proton-proton interaction between the supernova and the CO-rich surrounding., Comment: accepted for publication by MNRAS
Published: 2018
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174. Periastron Observations of TeV Gamma-Ray Emission from a Binary System with a 50-year Period

Author: The VERITAS Collaboration, Abeysekara, A. U., Benbow, W., Bird, R., Brill, A., Brose, R., Buckley, J. H., Chromey, A. J., Daniel, M. K., Falcone, A., Finley, J. P., Fortson, L., Furniss, A., Gent, A., Gillanders, G. H., Hanna, D., Hassan, T., Hervet, O., Holder, J., Hughes, G., Humensky, T. B., Kaaret, P., Kar, P., Kertzman, M., Kieda, D., Krause, M., Krennrich, F., Kumar, S., Lang, M. J., Lin, T. T. Y., Maier, G., Moriarty, P., Mukherjee, R., O'Brien, S., Ong, R. A., Otte, A. N., Park, N., Petrashyk, A., Pohl, M., Pueschel, E., Quinn, J., Ragan, K., Richards, G. T., Roache, E., Sadeh, I., Santander, M., Schlenstedt, S., Sembroski, G. H., Sushch, I., Tyler, J., Vassiliev, V. V., Wakely, S. P., Weinstein, A., Wells, R. M., Wilcox, P., Wilhelm, A., Williams, D. A., Williamson, T. J, Zitzer, B., Collaboration, MAGIC, Acciari, V. A., Ansoldi, S., Antonelli, L. A., Engels, A. Arbet, Baack, D., Babić, A., Banerjee, B., de Almeida, U. Barres, Barrio, J. A., González, J. Becerra, Bednarek, W., Bernardini, E., Berti, A., Besenrieder, J., Bhattacharyya, W., Bigongiari, C., Biland, A., Blanch, O., Bonnoli, G., Busetto, G., Carosi, R., Ceribella, G., Cikota, S., Colak, S. M., Colin, P., Colombo, E., Contreras, J. L., Cortina, J., Covino, S., D'Elia, V., Da Vela, P., Dazzi, F., De Angelis, A., De Lotto, B., Delfino, M., Delgado, J., Di Pierro, F., Espiñera, E. Do Souto, Domínguez, A., Prester, D. Dominis, Dorner, D., Doro, M., Einecke, S., Elsaesser, D., Ramazani, V. Fallah, Fattorini, A., Fernández-Barral, A., Ferrara, G., Fidalgo, D., Foffano, L., Fonseca, M. V., Font, L., Fruck, C., Galindo, D., Gallozzi, S., López, R. J. García, Garczarczyk, M., Gasparyan, S., Gaug, M., Giammaria, P., Godinović, N., Guberman, D., Hadasch, D., Hahn, A., Herrera, J., Hoang, J., Hrupec, D., Inoue, S., Ishio, K., Iwamura, Y., Kubo, H., Kushida, J., Kuveždić, D., Lamastra, A., Lelas, D., Leone, F., Lindfors, E., Lombardi, S., Longo, F., López, M., López-Oramas, A., Fraga, B. Machado de Oliveira, Maggio, C., Majumdar, P., Makariev, M., Mallamaci, M., Maneva, G., Manganaro, M., Mannheim, K., Maraschi, L., Mariotti, M., Martínez, M., Masuda, S., Mazin, D., Minev, M., Miranda, J. M., Mirzoyan, R., Molina, E., Moralejo, A., Moreno, V., Moretti, E., Munar-Adrover, P., Neustroev, V., Niedzwiecki, A., Rosillo, M. Nievas, Nigro, C., Nilsson, K., Ninci, D., Nishijima, K., Noda, K., Nogués, L., Nöthe, M., Paiano, S., Palacio, J., Paneque, D., Paoletti, R., Paredes, J. M., Pedaletti, G., Peñil, P., Peresano, M., Persic, M., Moroni, P. G. Prada, Prandini, E., Puljak, I., Garcia, J. R., Rhode, W., Ribó, M., Rico, J., Righi, C., Rugliancich, A., Saha, L., Sahakyan, N., Saito, T., Satalecka, K., Schweizer, T., Sitarek, J., Šnidarić, I., Sobczynska, D., Somero, A., Stamerra, A., Strzys, M., Surić, T., Tavecchio, F., Temnikov, P., Terzić, T., Teshima, M., Torres-Albà, N., Tsujimoto, S., van Scherpenberg, J., Vanzo, G., Acosta, M. Vazquez, Vovk, I., Will, M., and Zarić, D.
Subjects: Astrophysics - High Energy Astrophysical Phenomena
Abstract: We report on observations of the pulsar / Be star binary system PSR J2032+4127 / MT91 213 in the energy range between 100 GeV and 20 TeV with the VERITAS and MAGIC imaging atmospheric Cherenkov telescope arrays. The binary orbit has a period of approximately 50 years, with the most recent periastron occurring on 2017 November 13. Our observations span from 18 months prior to periastron to one month after. A new, point-like, gamma-ray source is detected, coincident with the location of PSR J2032+4127 / MT91 213. The gamma-ray light curve and spectrum are well-characterized over the periastron passage. The flux is variable over at least an order of magnitude, peaking at periastron, thus providing a firm association of the TeV source with the pulsar / Be star system. Observations prior to periastron show a cutoff in the spectrum at an energy around 0.5 TeV. This result adds a new member to the small population of known TeV binaries, and it identifies only the second source of this class in which the nature and properties of the compact object are firmly established. We compare the gamma-ray results with the light curve measured with the X-ray Telescope (XRT) on board the Neil Gehrels \textit{Swift} Observatory and with the predictions of recent theoretical models of the system. We conclude that significant revision of the models is required to explain the details of the emission we have observed, and we discuss the relationship between the binary system and the overlapping steady extended source, TeV J2032+4130., Comment: 12 pages, 3 figures, 1 table. Accepted for publication in ApJL
Published: 2018
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175. Nonscanning large-area Raman imaging for ex vivo/in vivo skin cancer discrimination

Author: Schmälzlin, Elmar, Moralejo, Benito, Gersonde, Ingo, Schleusener, Johannes, Darvin, Maxim E., Thiede, Gisela, and Roth, Martin M.
Subjects: Astrophysics - Instrumentation and Methods for Astrophysics, Physics - Medical Physics
Abstract: Imaging Raman spectroscopy can be used to identify cancerous tissue. Traditionally, a step-by-step scanning of the sample is applied to generate a Raman image, which, however, is too slow for routine examination of patients. By transferring the technique of integral field spectroscopy (IFS) from astronomy to Raman imaging, it becomes possible to record entire Raman images quickly within a single exposure, without the need for a tedious scanning procedure. An IFS-based Raman imaging setup is presented, which is capable of measuring skin ex vivo or in vivo. It is demonstrated how Raman images of healthy and cancerous skin biopsies were recorded and analyzed.
Published: 2018
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176. Constraining very-high-energy and optical emission from FRB 121102 with the MAGIC telescopes

Author: MAGIC Collaboration, Acciari, V. A., Ansoldi, S., Antonelli, L. A., Engels, A. Arbet, Arcaro, C., Baack, D., Babić, A., Banerjee, B., Bangale, P., de Almeida, U. Barres, Barrio, J. A., González, J. Becerra, Bednarek, W., Bernardini, E., Berti, A., Besenrieder, J., Bhattacharyya, W., Bigongiari, C., Biland, A., Blanch, O., Bonnoli, G., Carosi, R., Ceribella, G., Chatterjee, A., Colak, S. M., Colin, P., Colombo, E., Contreras, J. L., Cortina, J., Covino, S., Cumani, P., D'Elia, V., Da Vela, P., Dazzi, F., De Angelis, A., De Lotto, B., Delfino, M., Delgado, J., Di Pierro, F., Domínguez, A., Prester, D. Dominis, Dorner, D., Doro, M., Einecke, S., Elsaesser, D., Ramazani, V. Fallah, Fattorini, A., Fernández-Barral, A., Ferrara, G., Fidalgo, D., Foffano, L., Fonseca, M. V., Font, L., Fruck, C., Gallozzi, S., ópez, R. J. García, Garczarczyk, M., Gaug, M., Giammaria, P., Godinović, N., Guberman, D., Hadasch, D., Hahn, A., Hassan, T., Herrera, J., Hoang, J., Hrupec, D., Inoue, S., Ishio, K., Iwamura, Y., Kubo, H., Kushida, J., Kuveždić, D., Lamastra, A., Lelas, D., Leone, F., Lindfors, E., Lombardi, S., Longo, F., López, M., López-Oramas, A., Maggio, C., Majumdar, P., Makariev, M., Maneva, G., Manganaro, M., Mannheim, K., Maraschi, L., Mariotti, M., Martínez, M., Masuda, S., Mazin, D., Minev, M., Miranda, J. M., Mirzoyan, R., Molina, E., Moralejo, A., Moreno, V., Moretti, E., Neustroev, V., Niedzwiecki, A., Rosillo, M. Nievas, Nigro, C., Nilsson, K., Ninci, D., Nishijima, K., Noda, K., Nogués, L., Paiano, S., Palacio, J., Paneque, D., Paoletti, R., Paredes, J. M., Pedaletti, G., Peñil, P., Peresano, M., Persic, M., Moroni, P. G. Prada, Prandini, E., Puljak, I., Garcia, J. R., Rhode, W., Ribó, M., Rico, J., Righi, C., Rugliancich, A., Saha, L., Saito, T., Satalecka, K., Schweizer, T., Sitarek, J., Šnidarić, I., Sobczynska, D., Somero, A., Stamerra, A., Strzys, M., Surić, T., Tavecchio, F., Temnikov, P., Terzić, T., Teshima, M., Torres-Albà, N., Tsujimoto, S., Vanzo, G., Acosta, M. Vazquez, Vovk, I., Ward, J. E., Will, M., Zarić, D., Marcote, B., Spitler, L. G., Hessels, J. W. T., Kashiyama, K., Murase, K., Bosch-Ramon, V., Michilli, D., and Seymour, A.
Subjects: Astrophysics - High Energy Astrophysical Phenomena
Abstract: Fast radio bursts (FRBs) are bright flashes observed typically at GHz frequencies with millisecond duration, whose origin is likely extragalactic. Their nature remains mysterious, motivating searches for counterparts at other wavelengths. FRB 121102 is so far the only source known to repeatedly emit FRBs and is associated with a host galaxy at redshift $z \simeq 0.193$. We conducted simultaneous observations of FRB 121102 with the Arecibo and MAGIC telescopes during several epochs in 2016--2017. This allowed searches for millisecond-timescale burst emission in very-high-energy (VHE) gamma rays as well as the optical band. While a total of five FRBs were detected during these observations, no VHE emission was detected, neither of a persistent nature nor burst-like associated with the FRBs. The average integral flux upper limits above 100 GeV at 95% confidence level are $6.6 \times 10^{-12}~\mathrm{photons\ cm^{-2}\ s^{-1}}$ (corresponding to luminosity $L_{\rm VHE} \lesssim 10^{45}~\mathrm{erg\ s^{-1}}$) over the entire observation period, and $1.2 \times 10^{-7}~ \mathrm{photons\ cm^{-2}\ s^{-1}}$ ($L_{\rm VHE} \lesssim 10^{49}~\mathrm{erg\ s^{-1}}$) over the total duration of the five FRBs. We constrain the optical U-band flux to be below 8.6 mJy at 5-$\sigma$ level for 1-ms intervals around the FRB arrival times. A bright burst with U-band flux $29~\mathrm{mJy}$ and duration $\sim 12$ ms was detected 4.3 s before the arrival of one FRB. However, the probability of spuriously detecting such a signal within the sampled time space is 1.5% (2.2 $\sigma$, post-trial), i.e. consistent with the expected background. We discuss the implications of the obtained upper limits for constraining FRB models., Comment: 9 pages, 3 figures. Accepted for publication in MNRAS the 2nd September 2018
Published: 2018
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177. The extreme HBL behaviour of Markarian 501 during 2012

Author: Ahnen, M. L., Ansoldi, S., Antonelli, L. A., Arcaro, C., Babić, A., Banerjee, B., Bangale, P., de Almeida, U. Barres, Barrio, J. A., González, J. Becerra, Bednarek, W., Bernardini, E., Berti, A., Bhattacharyya, W., Blanch, O., Bonnoli, G., Carosi, R., Carosi, A., Chatterjee, A., Colak, S. M., Colin, P., Colombo, E., Contreras, J. L., Cortina, J., Covino, S., Cumani, P., Da Vela, P., Dazzi, F., De Angelis, A., De Lotto, B., Delfino, M., Delgado, J., Di Pierro, F., Doert, M., Domínguez, A., Prester, D. Dominis, Doro, M., Glawion, D. Eisenacher, Engelkemeier, M., Ramazani, V. Fallah, Fernández-Barral, A., Fidalgo, D., Fonseca, M. V., Font, L., Fruck, C., Galindo, D., López, R. J. García, Garczarczyk, M., Gaug, M., Giammaria, P., Godinović, N., Gora, D., Guberman, D., Hadasch, D., Hahn, A., Hassan, T., Hayashida, M., Herrera, J., Hose, J., Hrupec, D., Ishio, K., Konno, Y., Kubo, H., Kushida, J., Kuveždić, D., Lelas, D., Lindfors, E., Lombardi, S., Longo, F., López, M., Maggio, C., Majumdar, P., Makariev, M., Maneva, G., Manganaro, M., Maraschi, L., Mariotti, M., Martínez, M., Mazin, D., Menzel, U., Minev, M., Miranda, J. M., Mirzoyan, R., Moralejo, A., Moreno, V., Moretti, E., Nagayoshi, T., Neustroev, V., Niedzwiecki, A., Rosillo, M. Nievas, Nigro, C., Nilsson, K., Ninci, D., Nishijima, K., Noda, K., Nogués, L., Paiano, S., Palacio, J., Paneque, D., Paoletti, R., Paredes, J. M., Pedaletti, G., Peresano, M., Perri, L., Persic, M., Moroni, P. G. Prada, Prandini, E., Puljak, I., Garcia, J. R., Reichardt, I., Ribó, M., Rico, J., Righi, C., Rugliancich, A., Saito, T., Satalecka, K., Schroeder, S., Schweizer, T., Shore, S. N., Sitarek, J., Šnidarić, I., Sobczynska, D., Stamerra, A., Strzys, M., Surić, T., Takalo, L., Tavecchio, F., Temnikov, P., Terzić, T., Teshima, M., Torres-Albà, N., Treves, A., Tsujimoto, S., Vanzo, G., Acosta, M. Vazquez, Vovk, I., Ward, J. E., Will, M., Zarić, D., Arbet-Engels, A., Baack, D., Balbo, M., Biland, A., Blank, M., Bretz, T., Bruegge, K., Bulinski, M., Buss, J., Dmytriiev, A., Dorner, D., Einecke, S., Elsaesser, D., Herbst, T., Hildebrand, D., Kortmann, L., Linhoff, L., Mahlke, M., Mannheim, K., Mueller, S. A., Neise, D., Neronov, A., Noethe, M., Oberkirch, J., Paravac, A., Rhode, W., Schleicher, B., Schulz, F., Sedlaczek, K., Shukla, A., Sliusar, V., Walter, R., Archer, A., Benbow, W., Bird, R., Brose, R., Buckley, J. H., Bugaev, V., Christiansen, J. L., Cui, W., Daniel, M. K., Falcone, A., Feng, Q., Finley, J. P., Gillanders, G. H., Gueta, O., Hanna, D., Hervet, O., Holder, J., Hughes, G., Hütten, M., Humensky, T. B., Johnson, C. A., Kaaret, P., Kar, P., Kelley-Hoskins, N., Kertzman, M., Kieda, D., Krause, M., Krennrich, F., Kumar, S., Lang, M. J., Lin, T. T. Y., Maier, G., McArthur, S., Moriarty, P., Mukherjee, R., O'Brien, S., Ong, R. A., Otte, A. N., Park, N., Petrashyk, A., Pichel, A., Pohl, M., Quinn, J., Ragan, K., Reynolds, P. T., Richards, G. T., Roache, E., Rovero, A. C., Rulten, C., Sadeh, I., Santander, M., Sembroski, G. H., Shahinyan, K., Sushch, I., Tyler, J., Wakely, S. P., Weinstein, A., Wells, R. M., Wilcox, P., Wilhel, A., Williams, D. A., Williamson, T. J, Zitzer, B., Perri, M., Verrecchia, F., Leto, C., Villata, M., Raiteri, C. M., Jorstad, S. G., Larionov, V. M., Blinov, D. A., Grishina, T. S., Kopatskaya, E. N., Larionova, E. G., Nikiforova, A. A., Morozova, D. A., Troitskaya, Yu. V., Troitsky, I. S., Kurtanidze, O. M., Nikolashvili, M. G., Kurtanidze, S. O., Kimeridze, G. N., Chigladze, R. A., Strigachev, A., Sadun, A. C., Moody, J. W., Chen, W. P., Lin, H. C., Acosta-Pulido, J. A., Arévalo, M. J., Carnerero, M. I., González-Morales, P. A., Manilla-Robles, A., Jermak, H., Steele, I., Mundel, C., Benítez, E., Hiriart, D., Smith, P. S., Max-Moerbeck, W., Readhead, A. C. S., Richards, J. L., Hovatta, T., Lähteenmäki, A., Tornikoski, M., Tammi, J., Georganopoulos, M., and Baring, M. G.
Subjects: Astrophysics - High Energy Astrophysical Phenomena
Abstract: A multiwavelength campaign was organized to take place between March and July of 2012. Excellent temporal coverage was obtained with more than 25 instruments, including the MAGIC, FACT and VERITAS Cherenkov telescopes, the instruments on board the Swift and Fermi spacecraft, and the telescopes operated by the GASP-WEBT collaboration. Mrk 501 showed a very high energy (VHE) gamma-ray flux above 0.2 TeV of $\sim$0.5 times the Crab Nebula flux (CU) for most of the campaign. The highest activity occurred on 2012 June 9, when the VHE flux was $\sim$3 CU, and the peak of the high-energy spectral component was found to be at $\sim$2 TeV. This study reports very hard X-ray spectra, and the hardest VHE spectra measured to date for Mrk 501. The fractional variability was found to increase with energy, with the highest variability occurring at VHE, and a significant correlation between the X-ray and VHE bands. The unprecedentedly hard X-ray and VHE spectra measured imply that their low- and high-energy components peaked above 5 keV and 0.5 TeV, respectively, during a large fraction of the observing campaign, and hence that Mrk 501 behaved like an extreme high-frequency- peaked blazar (EHBL) throughout the 2012 observing season. This suggests that being an EHBL may not be a permanent characteristic of a blazar, but rather a state which may change over time. The one-zone synchrotron self-Compton (SSC) scenario can successfully describe the segments of the SED where most energy is emitted, with a significant correlation between the electron energy density and the VHE gamma-ray activity, suggesting that most of the variability may be explained by the injection of high-energy electrons. The one-zone SSC scenario used reproduces the behaviour seen between the measured X-ray and VHE gamma-ray fluxes, and predicts that the correlation becomes stronger with increasing energy of the X-rays., Comment: 25 pages, 9 figures, accepted for publication in A&A. Corresponding authors: Gareth Hughes (gareth.hughes@cfa.harvard.edu), David Paneque (dpaneque@mppmu.mpg.de), Amit Shukla (amit.shukla@astro.uni-wuerzburg.de)
Published: 2018
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178. The blazar TXS 0506+056 associated with a high-energy neutrino: insights into extragalactic jets and cosmic ray acceleration

Author: Ansoldi, S., Antonelli, L. A., Arcaro, C., Baack, D., Babić, A., Banerjee, B., Bangale, P., de Almeida, U. Barres, Barrio, J. A., González, J. Becerra, Bednarek, W., Bernardini, E., Berse, R. Ch., Berti, A., Besenrieder, J., Bhattacharyya, W., Bigongiari, C., Biland, A., Blanch, O., Bonnoli, G., Carosi, R., Ceribella, G., Chatterjee, A., Colak, S. M., Colin, P., Colombo, E., Contreras, J. L., Cortina, J., Covino, S., Cumani, P., D'Elia, V., Da Vela, P., Dazzi, F., De Angelis, A., De Lotto, B., Delfino, M., Delgado, J., Di Pierro, F., Domínguez, A., Prester, D. Dominis, Dorner, D., Doro, M., Einecke, S., Elsaesser, D., Ramazani, V. Fallah, Fattorini, A., Fernández-Barral, A., Ferrara, G., Fidalgo, D., Foffano, L., Fonseca, M. V., Font, L., Fruck, C., Gallozzi, S., López, R. J. García, Garczarczyk, M., Gaug, M., Giammaria, P., Godinović, N., Guberman, D., Hadasch, D., Hahn, A., Hassan, T., Hayashida, M., Herrera, J., Hoang, J., Hrupec, D., Inoue, S., Ishio, K., Iwamura, Y., Konno, Y., Kubo, H., Kushida, J., Lamastra, A., Lelas, D., Leone, F., Lindfors, E., Lombardi, S., Longo, F., López, M., Maggio, C., Majumdar, P., Makariev, M., Maneva, G., Manganaro, M., Mannheim, K., Maraschi, L., Mariotti, M., Martínez, M., Masuda, S., Mazin, D., Mielke, K., Minev, M., Miranda, J. M., Mirzoyan, R., Moralejo, A., Moreno, V., Moretti, E., Neustroev, V., Niedzwiecki, A., Rosillo, M. Nievas, Nigro, C., Nilsson, K., Ninci, D., Nishijima, K., Noda, K., Nogués, L., Paiano, S., Palacio, J., Paneque, D., Paoletti, R., Paredes, J. M., Pedaletti, G., Peñil, P., Peresano, M., Persic, M., Pfrang, K., Moroni, P. G. Prada, Prandini, E., Puljak, I., Garcia, J. R., Rhode, W., Ribó, M., Rico, J., Righi, C., Rugliancich, A., Saha, L., Saito, T., Satalecka, K., Schweizer, T., Sitarek, J., Šnidarić, I., Sobczynska, D., Stamerra, A., Strzys, M., Surić, T., Tavecchio, F., Temnikov, P., Terzić, T., Teshima, M., Torres-Albà, N., Tsujimoto, S., Vanzo, G., Acosta, M. Vazquez, Vovk, I., Ward, J. E., Will, M., Zarić, D., and Cerruti, Matteo
Subjects: Astrophysics - High Energy Astrophysical Phenomena
Abstract: A neutrino with energy of $\sim$290 TeV, IceCube-170922A, was detected in coincidence with the BL Lac object TXS~0506+056 during enhanced gamma-ray activity, with chance coincidence being rejected at $\sim 3\sigma$ level. We monitored the object in the very-high-energy (VHE) band with the MAGIC telescopes for $\sim$41 hours from 1.3 to 40.4 days after the neutrino detection. Day-timescale variability is clearly resolved. We interpret the quasi-simultaneous neutrino and broadband electromagnetic observations with a novel one-zone lepto-hadronic model, based on interactions of electrons and protons co-accelerated in the jet with external photons originating from a slow-moving plasma sheath surrounding the faster jet spine. We can reproduce the multiwavelength spectra of TXS 0506+056 with neutrino rate and energy compatible with IceCube-170922A, and with plausible values for the jet power of $\sim 10^{45} - 4 \times 10^{46} {\rm erg \ s^{-1}}$. The steep spectrum observed by MAGIC is concordant with internal $\gamma\gamma$ absorption above a few tens of GeV entailed by photohadronic production of a $\sim$290 TeV neutrino, corroborating a genuine connection between the multi-messenger signals. In contrast to previous predictions of predominantly hadronic emission from neutrino sources, the gamma-rays can be mostly ascribed to inverse Compton up-scattering of external photons by accelerated electrons. The X-ray and VHE bands provide crucial constraints on the emission from both accelerated electrons and protons. We infer that the maximum energy of protons in the jet co-moving frame can be in the range $\sim 10^{14}$ to $10^{18}$ eV., Comment: 11 pages, 3 figues, 3 tables, Accepted for publication in ApJL. Major changes in the revised Version: corrected author list
Published: 2018
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179. The broad-band properties of the intermediate synchrotron peaked BL Lac S2 0109+22 from radio to VHE gamma rays

Author: MAGIC Collaboration, Ansoldi, S., Antonelli, L. A., Arcaro, C., Baack, D., Babić, A., Banerjee, B., Bangale, P., de Almeida, U. Barres, Barrio, J. A., González, J. Becerra, Bednarek, W., Bernardini, E., Berse, R. Ch., Berti, A., Besenrieder, J., Bhattacharyya, W., Bigongiari, C., Biland, A., Blanch, O., Bonnoli, G., Carosi, R., Ceribella, G., Chatterjee, A., Colak, S. M., Colin, P., Colombo, E., Contreras, J. L., Cortina, J., Covino, S., Cumani, P., D'Elia, V., Da Vela, P., Dazzi, F., De Angelis, A., De Lotto, B., Delfino, M., Delgado, J., Di Pierro, F., Domínguez, A., Prester, D. Dominis, Dorner, D., Doro, M., Einecke, S., Elsaesser, D., Ramazani, V. Fallah, Fattorini, A., Fernández-Barral, A., Ferrara, G., Fidalgo, D., Foffano, L., Fonseca, M. V., Font, L., Fruck, C., Gallozzi, S., López, R. J. García, Garczarczyk, M., Gaug, M., Giammaria, P., Godinović, N., Guberman, D., Hadasch, D., Hahn, A., Hassan, T., Hayashida, M., Herrera, J., Hoang, J., Hrupec, D., Inoue, S., Ishio, K., Iwamura, Y., Konno, Y., Kubo, H., Kushida, J., Lamastra, A., Lelas, D., Leone, F., Lindfors, E., Lombardi, S., Longo, F., López, M., Maggio, C., Majumdar, P., Makariev, M., Maneva, G., Manganaro, M., Mannheim, K., Maraschi, L., Mariotti, M., Martínez, M., Masuda, S., Mazin, D., Mielke, K., Minev, M., Miranda, J. M., Mirzoyan, R., Moralejo, A., Moreno, V., Moretti, E., Neustroev, V., Niedzwiecki, A., Rosillo, M. Nievas, Nigro, C., Nilsson, K., Ninci, D., Nishijima, K., Noda, K., Nogués, L., Paiano, S., Palacio, J., Paneque, D., Paoletti, R., Paredes, J. M., Pedaletti, G., Penil, P., Peresano, M., Persic, M., Pfrang, K., Moroni, P. G. Prada, Prandini, E., Puljak, I., Garcia, J. R., Rhode, W., Ribó, M., Rico, J., Righi, C., Rugliancich, A., Saha, L., Saito, T., Satalecka, K., Schweizer, T., Sitarek, J., Šnidarić, I., Sobczynska, D., Stamerra, A., Strzys, M., Surić, T., Tavecchio, F., Temnikov, P., Terzić, T., Teshima, M., Torres-Albà, N., Tsujimoto, S., Vanzo, G., Acosta, M. Vazquez, Vovk, I., Ward, J. E., Will, M., Zarić, D., Collaboration, Fermi-LAT, Ciprini, S., Desiante, R., Collaborators, MWL, Barcewicz, S., Hovatta, T., Jormanainen, J., Takalo, L., Reinthal, R., Wierda, F., Lähteenmäki, A., Tammi, J., Tornikoski, M., Vera, R. J. C., Kiehlmann, S., Max-Moerbeck, W., and Readhead, A. C. S.
Subjects: Astrophysics - High Energy Astrophysical Phenomena
Abstract: The MAGIC telescopes observed S2 0109+22 in 2015 July during its flaring activity in high energy gamma rays observed by Fermi-LAT. We analyse the MAGIC data to characterise the very high energy (VHE) gamma-ray emission of S2 0109+22, which belongs to the subclass of intermediate synchrotron peak (ISP) BL Lac objects. We study the multi-frequency emission in order to investigate the source classification. Finally, we compare the source long-term behaviour to other VHE gamma-ray emitting (TeV) blazars. We performed a temporal and spectral analysis of the data centred around the MAGIC interval of observation (MJD 57225-57231). Long-term radio and optical data have also been investigated using the discrete correlation function. The redshift of the source is estimated through optical host-galaxy imaging and also using the amount of VHE gamma-ray absorption. The quasi-simultaneous multi-frequency spectral energy distribution (SED) is modelled with the conventional one-zone synchrotron self-Compton (SSC) model. MAGIC observations resulted in the detection of the source at a significance level of $5.3\,\sigma$. The VHE gamma-ray emission of S2 0109+22 is variable on a daily time scale. VHE gamma-ray luminosity of the source is lower than the average of TeV BL Lacs. The optical polarization, and long-term optical/radio behaviour of the source are different from the general population of TeV blazars. All these findings agree with the classification of the source as an ISP BL Lac object. We estimate the source redshift as $z = 0.36 \pm 0.07$. The SSC parameters describing the SED are rather typical for blazars., Comment: 15 pages, 10 figures, Corresponding authors: Fallah Ramazani, V. (vafara@utu.fi), Hovatta, T. (talvikki.hovatta@utu.fi), Lindfors, E. (elilin@utu.fi) and Nilsson, K. (kani@utu.fi)
Published: 2018
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180. Multi-wavelength characterization of the blazar S5~0716+714 during an unprecedented outburst phase

Author: MAGIC Collaboration, Ahnen, M. L., Ansoldi, S., Antonelli, L. A., Arcaro, C., Baack, D., Babić, A., Banerjee, B., Bangale, P., de Almeida, U. Barres, Barrio, J. A., González, J. Becerra, Bednarek, W., Bernardini, E., Berse, R. Ch., Berti, A., Bhattacharyya, W., Biland, A., Blanch, O., Bonnoli, G., Carosi, R., Carosi, A., Ceribella, G., Chatterjee, A., Colak, S. M., Colin, P., Colombo, E., Contreras, J. L., Cortina, J., Covino, S., Cumani, P., Da Vela, P., Dazzi, F., De Angelis, A., De Lotto, B., Delfino, M., Delgado, J., Di Pierro, F., Domínguez, A., Prester, D. Dominis, Dorner, D., Doro, M., Einecke, S., Elsaesser, D., Ramazani, V. Fallah, Fernández-Barral, A., Fidalgo, D., Fonseca, M. V., Font, L., Fruck, C., Galindo, D., Gallozzi, S., López, R. J. García, Garczarczyk, M., Gaug, M., Giammaria, P., Godinović, N., Gora, D., Guberman, D., Hadasch, D., Hahn, A., Hassan, T., Hayashida, M., Herrera, J., Hose, J., Hrupec, D., Ishio, K., Konno, Y., Kubo, H., Kushida, J., Kuveždić, D., Lelas, D., Lindfors, E., Lombardi, S., Longo, F., López, M., Maggio, C., Majumdar, P., Makariev, M., Maneva, G., Manganaro, M., Mannheim, K., Maraschi, L., Mariotti, M., Martínez, M., Masuda, S., Mazin, D., Mielke, K., Minev, M., Miranda, J. M., Mirzoyan, R., Moralejo, A., Moreno, V., Moretti, E., Nagayoshi, T., Neustroev, V., Niedzwiecki, A., Rosillo, M. Nievas, Nigro, C., Nilsson, K., Ninci, D., Nishijima, K., Noda, K., Nogués, L., Paiano, S., Palacio, J., Paneque, D., Paoletti, R., Paredes, J. M., Pedaletti, G., Peresano, M., Persic, M., Moroni, P. G. Prada, Prandini, E., Puljak, I., Garcia, J. R., Reichardt, I., Rhode, W., Ribó, M., Rico, J., Righi, C., Rugliancich, A., Saito, T., Satalecka, K., Schweizer, T., Sitarek, J., Šnidarić, I., Sobczynska, D., Stamerra, A., Strzys, M., Surić, T., Takahashi, M., Takalo, L., Tavecchio, F., Temnikov, P., Terzić, T., Teshima, M., Torres-Albà, N., Treves, A., Tsujimoto, S., Vanzo, G., Acosta, M. Vazquez, Vovk, I., Ward, J. E., Will, M., Zarić, D., Collaboration, Fermi-LAT, Bastieri, D., Gasparrini, D., Lott, B., Rani, B., Thompson, D. J., Collaborators, MWL, Agudo, I., Angelakis, E., Borman, G. A., Casadio, C., Grishina, T. S., Gurwell, M., Hovatta, T., Itoh, R., Järvelä, E., Jermak, H., Jorstad, S., Kopatskaya, E. N., Kraus, A., Krichbaum, T. P., Kuin, N. P. M., Lähteenmäki, A., Larionov, V. M., Larionova, L. V., Lien, A. Y., Madejski, G., Marscher, A., Myserlis, I., Max-Moerbeck, W., Molina, S. N., Morozova, D. A., Nalewajko, K., Pearson, T. J., Ramakrishnan, V., Readhead, A. C. S., Reeves, R. A., Savchenko, S. S., Steele, I. A., Tornikoski, M., Troitskaya, Yu. V., Troitsky, I., Vasilyev, A. A., and Zensus, J. Anton
Subjects: Astrophysics - High Energy Astrophysical Phenomena
Abstract: The BL Lac object S5~0716+714, a highly variable blazar, underwent an impressive outburst in January 2015 (Phase A), followed by minor activity in February (Phase B). The MAGIC observations were triggered by the optical flux observed in Phase A, corresponding to the brightest ever reported state of the source in the R-band. The comprehensive dataset collected is investigated in order to shed light on the mechanism of the broadband emission. Multi-wavelength light curves have been studied together with the broadband Spectral Energy Distributions (SEDs). The data set collected spans from radio, optical photometry and polarimetry, X-ray, high-energy (HE, 0.1 GeV < E < 100 GeV) with \textit{Fermi}-LAT to the very-high-energy (VHE, E>100 GeV) with MAGIC. The flaring state of Phase A was detected in all the energy bands, providing for the first time a multi-wavelength sample of simultaneous data from the radio band to the VHE. In the constructed SED the \textit{Swift}-XRT+\textit{NuSTAR} data constrain the transition between the synchrotron and inverse Compton components very accurately, while the second peak is constrained from 0.1~GeV to 600~GeV by \textit{Fermi}+MAGIC data. The broadband SED cannot be described with a one-zone synchrotron self-Compton model as it severely underestimates the optical flux in order to reproduce the X-ray to $\gamma$-ray data. Instead we use a two-zone model. The EVPA shows an unprecedented fast rotation. An estimation of the redshift of the source by combined HE and VHE data provides a value of $z = 0.31 \pm 0.02_{stats} \pm 0.05_{sys}$, confirming the literature value. The data show the VHE emission originating in the entrance and exit of a superluminal knot in and out a recollimation shock in the inner jet. A shock-shock interaction in the jet seems responsible for the observed flares and EVPA swing. This scenario is also consistent with the SED modelling.
Published: 2018
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181. Answers linked to Gould DJ, Creedon S, Jeanes A, Drey NS, Chudleigh J, Moralejo D. Impact of observing hand hygiene in practice and research: a methodological reconsideration. J Hosp Infect 2017;95:169–174

Published: 2017
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182. Constraining Dark Matter lifetime with a deep gamma-ray survey of the Perseus Galaxy Cluster with MAGIC

Author: MAGIC Collaboration, Acciari, V. A., Ansoldi, S., Antonelli, L. A., Engels, A. Arbet, Baack, D., Babić, A., Banerjee, B., Bangale, P., de Almeida, U. Barres, Barrio, J. A., González, J. Becerra, Bednarek, W., Bernardini, E., Berti, A., Besenrieder, J., Bhattacharyya, W., Bigongiari, C., Biland, A., Blanch, O., Bonnoli, G., Carosi, R., Ceribella, G., Cikota, S., Colak, S. M., Colin, P., Colombo, E., Contreras, J. L., Cortina, J., Covino, S., D'Elia, V., Da Vela, P., Dazzi, F., De Angelis, A., De Lotto, B., Delfino, M., Delgado, J., Di Pierro, F., Espiñera, E. Do Souto, Domínguez, A., Prester, D. Dominis, Dorner, D., Doro, M., Einecke, S., Elsaesser, D., Ramazani, V. Fallah, Fattorini, A., Fernández-Barral, A., Ferrara, G., Fidalgo, D., Foffano, L., Fonseca, M. V., Font, L., Fruck, C., Galindo, D., Gallozzi, S., López, R. J. García, Garczarczyk, M., Gaug, M., Giammaria, P., Godinović, N., Guberman, D., Hadasch, D., Hahn, A., Hassan, T., Herrera, J., Hoang, J., Hrupec, D., Inoue, S., Ishio, K., Iwamura, Y., Kubo, H., Kushida, J., Kuveždić, D., Lamastra, A., Lelas, D., Leone, F., Lindfors, E., Lombardi, S., Longo, F., López, M., López-Oramas, A., Maggio, C., Majumdar, P., Makariev, M., Maneva, G., Manganaro, M., Mannheim, K., Maraschi, L., Mariotti, M., Martínez, M., Masuda, S., Mazin, D., Minev, M., Miranda, J. M., Mirzoyan, R., Molina, E., Moralejo, A., Moreno, V., Moretti, E., Munar-Adrover, P., Neustroev, V., Niedzwiecki, A., Rosillo, M. Nievas, Nigro, C., Nilsson, K., Ninci, D., Nishijima, K., Noda, K., Nogués, L., Paiano, S., Palacio, J., Paneque, D., Paoletti, R., Paredes, J. M., Pedaletti, G., Peñil, P., Peresano, M., Persic, M., Moroni, P. G. Prada, Prandini, E., Puljak, I., Garcia, J. R., Rhode, W., Ribó, M., Rico, J., Righi, C., Rugliancich, A., Saha, L., Saito, T., Satalecka, K., Schweizer, T., Sitarek, J., Šnidarić, I., Sobczynska, D., Somero, A., Stamerra, A., Strzys, M., Surić, T., Tavecchio, F., Temnikov, P., Terzić, T., Teshima, M., Torres-Albà, N., Tsujimoto, S., Vanzo, G., Acosta, M. Vazquez, Vovk, I., Ward, J. E., Will, M., and Zarić, D.
Subjects: Astrophysics - High Energy Astrophysical Phenomena
Abstract: Clusters of galaxies are the largest known gravitationally bound structures in the Universe, with masses around $10^{15}\ M_\odot$, most of it in the form of dark matter. The ground-based Imaging Atmospheric Cherenkov Telescope MAGIC made a deep survey of the Perseus cluster of galaxies using almost 400 h of data recorded between 2009 and 2017. This is the deepest observational campaign so far on a cluster of galaxies in the very high energy range. We search for gamma-ray signals from dark matter particles in the mass range between 200 GeV and 200 TeV decaying into standard model pairs. We apply an analysis optimized for the spectral and morphological features expected from dark matter decays and find no evidence of decaying dark matter. From this, we conclude that dark matter particles have a decay lifetime longer than $\sim10^{26}$~s in all considered channels. Our results improve previous lower limits found by MAGIC and represent the strongest limits on decaying dark matter particles from ground-based gamma-ray instruments., Comment: 5 figures, corresponding authors: Joaquim Palacio (jpalacio@ifae.es), Michele Doro (michele.doro@unipd.it), M\'onica Vazquez-Acosta (monicava@iac.es) and Javier Rico (jrico@ifae.es)
Published: 2018
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183. Detection of persistent VHE gamma-ray emission from PKS 1510-089 by the MAGIC telescopes during low states between 2012 and 2017

Author: MAGIC Collaboration, Acciari, V. A., Ansoldi, S., Antonelli, L. A., Engels, A. Arbet, Arcaro, C., Baack, D., Babić, A., Banerjee, B., Bangale, P., de Almeida, U. Barres, Barrio, J. A., González, J. Becerra, Bednarek, W., Bernardini, E., Berti, A., Besenrieder, J., Bhattacharyya, W., Bigongiari, C., Biland, A., Blanch, O., Bonnoli, G., Carosi, R., Ceribella, G., Chatterjee, A., Colak, S. M., Colin, P., Colombo, E., Contreras, J. L., Cortina, J., Covino, S., Cumani, P., D'Elia, V., Da Vela, P., Dazzi, F., De Angelis, A., De Lotto, B., Delfino, M., Delgado, J., Di Pierro, F., Domínguez, A., Prester, D. Dominis, Dorner, D., Doro, M., Einecke, S., Elsaesser, D., Ramazani, V. Fallah, Fattorini, A., Fernández-Barral, A., Ferrara, G., Fidalgo, D., Foffano, L., Fonseca, M. V., Font, L., Fruck, C., Gallozzi, S., López, R. J. García, Garczarczyk, M., Gaug, M., Giammaria, P., Godinović, N., Guberman, D., Hadasch, D., Hahn, A., Hassan, T., Herrera, J., Hoang, J., Hrupec, D., Inoue, S., Ishio, K., Iwamura, Y., Kubo, H., Kushida, J., Kuveždić, D., Lamastra, A., Lelas, D., Leone, F., Lindfors, E., Lombardi, S., Longo, F., López, M., López-Oramas, A., Maggio, C., Majumdar, P., Makariev, M., Maneva, G., Manganaro, M., Mannheim, K., Maraschi, L., Mariotti, M., Martínez, M., Masuda, S., Mazin, D., Minev, M., Miranda, J. M., Mirzoyan, R., Molina, E., Moralejo, A., Moreno, V., Moretti, E., Neustroev, V., Niedzwiecki, A., Rosillo, M. Nievas, Nigro, C., Nilsson, K., Ninci, D., Nishijima, K., Noda, K., Nogués, L., Paiano, S., Palacio, J., Paneque, D., Paoletti, R., Paredes, J. M., Pedaletti, G., Peñil, P., Peresano, M., Persic, M., Moroni, P. G. Prada, Prandini, E., Puljak, I., Garcia, J. R., Rhode, W., Ribó, M., Rico, J., Righi, C., Rugliancich, A., Saha, L., Saito, T., Satalecka, K., Schweizer, T., Sitarek, J., Šnidarić, I., Sobczynska, D., Somero, A., Stamerra, A., Strzys, M., Surić, T., Tavecchio, F., Temnikov, P., Terzić, T., Teshima, M., Torres-Albà, N., Tsujimoto, S., Vanzo, G., Acosta, M. Vazquez, Vovk, I., Ward, J. E., Will, M., Zarić, D., Raiteri, C. M., Sandrinelli, A., Hovatta, T., Kiehlmann, S., Max-Moerbeck, W., Tornikoski, M., Lähteenmäki, A., Tammi, J., Ramakrishnan, V., Thum, C., Agudo, I., Molina, S. N., Gómez, J. L., Fuentes, A., Casadio, C., Traianou, E., Myserlis, I., and Kim, J. -Y.
Subjects: Astrophysics - Astrophysics of Galaxies
Abstract: PKS 1510-089 is a flat spectrum radio quasar strongly variable in the optical and GeV range. We search for low-state VHE gamma-ray emission from PKS 1510-089. We aim to characterize and model the source in a broad-band context, which would provide a baseline over which high states and flares could be better understood. We use daily binned Fermi-LAT flux measurements of PKS 1510-089 to characterize the GeV emission and select the observation periods of MAGIC during low state of activity. For the selected times we compute the average radio, IR, optical, UV, X-ray and gamma-ray emission to construct a low-state spectral energy distribution of the source. The broadband emission is modelled within an External Compton scenario with a stationary emission region through which plasma and magnetic field are flowing. We perform also the emission-model-independent calculations of the maximum absorption in the broad line region (BLR) using two different models. Results. The MAGIC telescopes collected 75 hrs of data during times when the Fermi-LAT flux measured above 1 GeV was below 3x10-8cm-2s-1, which is the threshold adopted for the definition of a low gamma-ray activity state. The data show a strongly significant (9.5{\sigma}) VHE gamma-ray emission at the level of (4.27+-0.61stat)x10-12cm-2s-1 above 150GeV, a factor 80 smaller than the highest flare observed so far from this object. Despite the lower flux, the spectral shape is consistent with earlier detections in the VHE band. The broad-band emission is compatible with the EC scenario assuming a large emission region located beyond the BLR. For the first time the gamma-ray data allow us to place a limit on the location of the emission region during a low gamma-ray state of a FSRQ. For the used model of the BLR, the 95% C.L. on the location of the emission region allows us to place it at the distance >74% of the outer radius of the BLR., Comment: 12 pages, 7 figures, accepted for publication in A&A
Published: 2018
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184. Gamma-ray flaring activity of NGC 1275 in 2016-2017 measured by MAGIC

Author: MAGIC collaboration, Ansoldi, S., Antonelli, L. A., Arcaro, C., Baack, D., Babić, A., Banerjee, B., Bangale, P., de Almeida, U. Barres, Barrio, J. A., González, J. Becerra, Bednarek, W., Bernardini, E., Berse, R. Ch., Berti, A., Bhattacharyya, W., Bigongiari, C., Biland, A., Blanch, O., Bonnoli, G., Carosi, R., Ceribella, G., Chatterjee, A., Colak, S. M., Colin, P., Colombo, E., Contreras, J. L., Cortina, J., Covino, S., Cumani, P., D'Elia, V., Da Vela, P., Dazzi, F., De Angelis, A., De Lotto, B., Delfino, M., Delgado, J., Di Pierro, F., Domínguez, A., Prester, D. Dominis, Dorner, D., Doro, M., Einecke, S., Elsaesser, D., Ramazani, V. Fallah, Fattorini, A., Fernández-Barral, A., Ferrara, G., Fidalgo, D., Foffano, L., Fonseca, M. V., Font, L., Fruck, C., Galindo, D., Gallozzi, S., López, R. J. García, Garczarczyk, M., Gaug, M., Giammaria, P., Godinović, N., Gora, D., Guberman, D., Hadasch, D., Hahn, A., Hassan, T., Hayashida, M., Herrera, J., Hoang, J., Hose, J., Hrupec, D., Ishio, K., Konno, Y., Kubo, H., Kushida, J., Lamastra, A., Lelas, D., Leone, F., Lindfors, E., Lombardi, S., Longo, F., López, M., Maggio, C., Majumdar, P., Makariev, M., Maneva, G., Manganaro, M., Mannheim, K., Maraschi, L., Mariotti, M., Martínez, M., Masuda, S., Mazin, D., Mielke, K., Minev, M., Miranda, J. M., Mirzoyan, R., Moralejo, A., Moreno, V., Moretti, E., Nagayoshi, T., Neustroev, V., Niedzwiecki, A., Rosillo, M. Nievas, Nigro, C., Nilsson, K., Ninci, D., Nishijima, K., Noda, K., Nogués, L., Paiano, S., Palacio, J., Paneque, D., Paoletti, R., Paredes, J. M., Pedaletti, G., Peñil, P., Peresano, M., Persic, M., Pfrang, K., Moroni, P. G. Prada, Prandini, E., Puljak, I., Garcia, J. R., Reichardt, I., Rhode, W., Ribó, M., Rico, J., Righi, C., Rugliancich, A., Saha, L., Saito, T., Satalecka, K., Schweizer, T., Sitarek, J., Šnidarić, I., Sobczynska, D., Stamerra, A., Strzys, M., Surić, T., Takahashi, M., Tavecchio, F., Temnikov, P., Terzić, T., Teshima, M., Torres-Albà, N., Tsujimoto, S., Vanzo, G., Acosta, M. Vazquez, Vovk, I., Ward, J. E., Will, M., Zarić, D., Glawion, D., Takalo, L. O., and Jormanainen, J.
Subjects: Astrophysics - High Energy Astrophysical Phenomena
Abstract: We report on the detection of flaring activity from the Fanaroff-Riley I radio galaxy NGC 1275 in very-high-energy (VHE, E $>$ 100 GeV) gamma rays with the MAGIC telescopes. Observations were performed between 2016 September and 2017 February as part of a monitoring program. The brightest outburst with $\sim1.5$ times the Crab Nebula flux above 100 GeV (C.U.) was observed during the night between 2016 December 31 and 2017 January 1 (fifty times higher than the mean previously measured in two observational campaigns between 2009 and 2011). Significant variability of the day-by-day light curve was measured, the shortest flux-doubling time-scales was found to be of $(611\pm101)$ min. The combined spectrum of the MAGIC data during the strongest flare state and simultaneous data from the Fermi-LAT around 2017 January 1 follows a power-law with an exponential cutoff at the energy $(492\pm35)$ GeV. Simultaneous optical flux density measurements in the R-band obtained with the KVA telescope are also presented and the correlation between the optical and gamma-ray emission is investigated. Due to possible internal pair-production, the fast flux variability constrains the Doppler factor to values which are inconsistent with a large viewing angle as observed in the radio band. We investigate different scenarios for the explanation of fast gamma-ray variability, namely emission from: magnetospheric gaps, relativistic blobs propagating in the jet (mini-jets) or external cloud (or star) entering the jet. We find that the only plausible model to account for the luminosities here observed would be the production of gamma rays in a magnetospheric gap around the central black hole only in the eventuality of an enhancement of the magnetic field threading the hole from its equipartition value with the gas pressure in the accretion flow., Comment: accepted for publications in Astronomy and Astrophysics
Published: 2018
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185. Limits on the flux of tau neutrinos from 1 PeV to 3 EeV with the MAGIC telescopes

Author: MAGIC Collaboration, Ahnen, M. L., Ansoldi, S., Antonelli, L. A., Arcaro, C., Baack, D., Babić, A., Banerjee, B., Bangale, P., de Almeida, U. Barres, Barrio, J. A., González, J. Becerra, Bednarek, W., Bernardini, E., Berse, R. Ch., Berti, A., Bhattacharyya, W., Biland, A., Blanch, O., Bonnoli, G., Carosi, R., Carosi, A., Ceribella, G., Chatterjee, A., Colak, S. M., Colin, P., Colombo, E., Contreras, J. L., Cortina, J., Covino, S., Cumani, P., Da Vela, P., Dazzi, F., De Angelis, A., De Lotto, B., Delfino, M., Delgado, J., Di Pierro, F., Domínguez, A., Prester, D. Dominis, Dorner, D., Doro, M., Einecke, S., Elsaesser, D., Ramazani, V. Fallah, Fernández-Barral, A., Fidalgo, D., Fonseca, M. V., Font, L., Fruck, C., Galindo, D., López, R. J. García, Garczarczyk, M., Gaug, M., Giammaria, P., Godinović, N., Góra, D., Guberman, D., Hadasch, D., Hahn, A., Hassan, T., Hayashida, M., Herrera, J., Hose, J., Hrupec, D., Ishio, K., Konno, Y., Kubo, H., Kushida, J., Kuveždić, D., Lelas, D., Lindfors, E., Lombardi, S., Longo, F., López, M., Maggio, C., Majumdar, P., Makariev, M., Maneva, G., Manganaro, M., Mannheim, K., Maraschi, L., Mariotti, M., Martínez, M., Masuda, S., Mazin, D., Mielke, K., Minev, M., Miranda, J. M., Mirzoyan, R., Moralejo, A., Moreno, V., Moretti, E., Nagayoshi, T., Neustroev, V., Niedzwiecki, A., Rosillo, M. Nievas, Nigro, C., Nilsson, K., Ninci, D., Nishijima, K., Noda, K., Nogués, L., Paiano, S., Palacio, J., Paneque, D., Paoletti, R., Paredes, J. M., Pedaletti, G., Peresano, M., Persic, M., Moroni, P. G. Prada, Prandini, E., Puljak, I., Garcia, J. R., Reichardt, I., Rhode, W., Ribó, M., Rico, J., Righi, C., Rugliancich, A., Saito, T., Satalecka, K., Schweizer, T., Sitarek, J., Šnidarić, I., Sobczynska, D., Stamerra, A., Strzys, M., Surić, T., Takahashi, M., Takalo, L., Tavecchio, F., Temnikov, P., Terzić, T., Teshima, M., Torres-Albà, N., Treves, A., Tsujimoto, S., Vanzo, G., Acosta, M. Vazquez, Vovk, I., Ward, J. E., Will, M., and Zarić, D.
Subjects: Astrophysics - Instrumentation and Methods for Astrophysics, Astrophysics - High Energy Astrophysical Phenomena
Abstract: A search for tau neutrino induced showers with the MAGIC telescopes is presented. The MAGIC telescopes located at an altitude of 2200 m a.s.l. in the Canary Island of La Palma, can point towards the horizon or a few degrees below across an azimuthal range of about 80 degrees. This provides a possibility to search for air showers induced by tau leptons arising from interactions of tau neutrinos in the Earth crust or the surrounding ocean. In this paper we show how such air showers can be discriminated from the background of very inclined hadronic showers by using Monte Carlo simulations. Taking into account the orography of the site, the point source acceptance and the event rates expected have been calculated for a sample of generic neutrino fluxes from photo-hadronic interactions in AGNs. The analysis of about 30 hours of data taken towards the sealeads to a 90\% C.L. point source limit for tau neutrinos in the energy range from $1.0 \times 10^{15}$ eV to $3.0 \times 10^{18}$ eV of about $E_{\nu_{\tau}}^{2}\times \phi (E_{\nu_{\tau}}) < 2.0 \times 10^{-4}$ GeV cm$^{-2}$ s$^{-1}$ for an assumed power-law neutrino spectrum with spectral index $\gamma$=-2. However, with 300 hours and in case of an optimistic neutrino flare model, limits of the level down to $E_{\nu_{\tau}}^{2}\times \phi (E_{\nu_{\tau}}) < 8.4 \times 10^{-6}$ GeV cm$^{-2}$ s$^{-1}$ can be expected., Comment: accepted for publication in Astroparticle Physics
Published: 2018
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186. Questions linked to Gould DJ, Creedon S, Jeanes A, Drey NS, Chudleigh J, Moralejo D. Impact of observing hand hygiene in practice and research: a methodological reconsideration. J Hosp Infect 2017;95:169–174

Published: 2017
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187. Emergence of a Plant Pathogen in Europe Associated with Multiple Intercontinental Introductions.

Author: Landa, Blanca B, Castillo, Andreina I, Giampetruzzi, Annalisa, Kahn, Alexandra, Román-Écija, Miguel, Velasco-Amo, María Pilar, Navas-Cortés, Juan A, Marco-Noales, Ester, Barbé, Silvia, Moralejo, Eduardo, Coletta-Filho, Helvecio D, Saldarelli, Pasquale, Saponari, Maria, and Almeida, Rodrigo PP
Subjects: Genetics, Infection, Brazil, Europe, Genome, Bacterial, Introduced Species, Plant Diseases, Whole Genome Sequencing, Xylella, Xylella fastidiosa, emerging disease, genomic diversity, outbreaks, recombination, quarantine, Xylella fastidiosa, Microbiology
Abstract: Pathogen introductions have led to numerous disease outbreaks in naive regions of the globe. The plant pathogen Xylella fastidiosa has been associated with various recent epidemics in Europe affecting agricultural crops, such as almond, grapevine, and olive, but also endemic species occurring in natural forest landscapes and ornamental plants. We compared whole-genome sequences of X. fastidiosa subspecies multiplex from America and strains associated with recent outbreaks in southern Europe to infer their likely origins and paths of introduction within and between the two continents. Phylogenetic analyses indicated multiple introductions of X. fastidiosa subspecies multiplex into Italy, Spain, and France, most of which emerged from a clade with limited genetic diversity with a likely origin in California, USA. The limited genetic diversity observed in X. fastidiosa subspecies multiplex strains originating from California is likely due to the clade itself being an introduction from X. fastidiosa subspecies multiplex populations in the southeastern United States, where this subspecies is most likely endemic. Despite the genetic diversity found in some areas in Europe, there was no clear evidence of recombination occurring among introduced X. fastidiosa strains in Europe. Sequence type taxonomy, based on multilocus sequence typing (MLST), was shown, at least in one case, to not lead to monophyletic clades of this pathogen; whole-genome sequence data were more informative in resolving the history of introductions than MLST data. Although additional data are necessary to carefully tease out the paths of these recent dispersal events, our results indicate that whole-genome sequence data should be considered when developing management strategies for X. fastidiosa outbreaks.IMPORTANCEXylella fastidiosa is an economically important plant-pathogenic bacterium that has emerged as a pathogen of global importance associated with a devastating epidemic in olive trees in Italy associated with X. fastidiosa subspecies pauca and other outbreaks in Europe, such as X. fastidiosa subspecies fastidiosa and X. fastidiosa subspecies multiplex in Spain and X. fastidiosa subspecies multiplex in France. We present evidence of multiple introductions of X. fastidiosa subspecies multiplex, likely from the United States, into Spain, Italy, and France. These introductions illustrate the risks associated with the commercial trade of plant material at global scales and the need to develop effective policy to limit the likelihood of pathogen pollution into naive regions. Our study demonstrates the need to utilize whole-genome sequence data to study X. fastidiosa introductions at outbreak stages, since a limited number of genetic markers does not provide sufficient phylogenetic resolution to determine dispersal paths or relationships among strains that are of biological and quarantine relevance.
Published: 2020

188. Recensión de la obra: La jurisprudencia del Tribunal de Justicia de la Unión Europea en materia de propiedad intelectual. Análisis y comentarios. Rafael Sánchez Aristi, Nieves Moralejo Imbernón, Sebastián López Maza. Editorial Fundación SGAE. Departamento de publicaciones. Primera edición, 2017. (930 páginas)

Author: Jerez Delgado, Carmen and UAM. Departamento de Derecho Privado, Social y Económico
Subjects: Derecho, Comentario de sentencias, Jurisprudencia, Derechos de la propiedad intelectual, Tribunal de Justicia de la Unión Europea
Published: 2017

189. Linking intercontinental biogeographic events to decipher how European vineyards escaped Pierce's disease.

Author: Moralejo, Eduardo, Giménez-Romero, Àlex, and Matías, Manuel A.
Subjects: XYLELLA fastidiosa, BIOLOGICAL invasions, GLOBAL warming, PHYLLOXERA, GRAPES
Abstract: Global change is believed to be a major driver of the emergence of invasive pathogens. Yet, there are few documented examples that illustrate the processes that hinder or trigger their geographic spread. Here, we present phylogenetic, epidemiological and historical evidence to explain how European vineyards escaped Xylella fastidiosa (Xf), the vector-borne bacterium responsible for Pierce's disease (PD). Using Bayesian temporal reconstruction, we show that the export of American grapevines to France as rootstocks to combat phylloxera (~1872–1895) preceded the spread of the Xf grapevine lineage in the USA. We found that the time of the most recent common ancestor in California dates to around 1875, which agrees with the emergence of the first PD outbreak and the expansion into the southeastern US around 1895. We also show that between 1870 and 1990, climatic conditions in continental Europe were mostly below the threshold for the development of PD epidemics. However, our model indicates an inadvertent expansion of risk in southern Europe since the 1990s, which is accelerating with global warming. Our temporal approach identifies the biogeographical conditions that have so far prevented PD in southern European wine-producing areas and predicts that disease risk will increase substantially with increasing temperatures. [ABSTRACT FROM AUTHOR]
Published: 2024
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190. Metabolic profiling of (poly)phenolic compounds in mouse urine following consumption of hull-less and purple-grain barley.

Author: Cortijo-Alfonso, María-Engracia, Yuste, Silvia, Friero, Iván, Martínez-Subirà, Mariona, Moralejo, Marian, Piñol-Felis, Carme, Rubió-Piqué, Laura, and Macià, Alba
Published: 2024
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191. Protocolo diagnóstico y terapéutico de las micosis pulmonares

Author: de la Sota, R., Gómez, J.A. Abad, Moralejo, R. Alonso, and Loaiza, C.A. Quezada
Published: 2022
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192. Neumonía adquirida en la comunidad

Author: Gómez, J.A. Abad, Loaiza, C.A. Quezada, and Moralejo, R. Alonso
Published: 2022
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193. Immunity After Vaccination Against SARS-CoV-2 in Lung Transplant?

Author: López, Gema María Siesto, Moralejo, Rodrigo Alonso, Roncal, María Piñeiro, Ortiz, María Teresa Tejedor, Loaiza, Carlos Andrés Quezada, Rivilla, Alfredo Pérez, and Gafas, Alicia De Pablo
Published: 2022
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194. Church's Chicken Appoints Tony Moralejo as Chief Development Officer

Subjects: Burger King Corp. -- Officials and employees, Restaurant industry -- Officials and employees, Arts and entertainment industries
Abstract: Church's Chicken President and Chief Executive Officer, Jim Hyatt announced the appointment of Tony Moralejo as its Chief Development Officer responsible for domestic and international expansion for the chicken chain. [...]
Published: 2013

195. Rafael GONZÁLEZ MORALEJO, El Vaticano II en taquigrafia. La historia de la «Gaudium et spes», BAC («Estudios y Ensayos-Historia»), Madrid 2000, 224 pp

Author: N.M. De Souza
Subjects: History, Religious studies
Published: 2018
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196. Gaspar CALVO MORALEJO, Teología de la vida religiosa en la restauración de la Orden Franciscana en España (1836-1856), Ed. Cisneros (Publicaciones de Archivo Ibero Americano), Madrid 1984, 102 pp., 16,5 x 23

Author: A. M. Pazos
Subjects: Religious studies
Published: 2018
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197. Survival analysis of patients with prostate cancer and unfavorable risk factors treated with radical prostatectomy and salvage radiotherapy after biochemical recurrence and persistence

Author: Barbas Bernardos, G., Herranz Amo, F., González San Segundo, C., Caño Velasco, J., Subirá Ríos, D., Moralejo Gárate, M., Mayor de Castro, J., Aragón Chamizo, J., and Hernández Fernández, C.
Published: 2020
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198. Analysis of recurrence trends according to risk groups after renal cancer nephrectomy

Author: Polanco Pujol, L., Herranz Amo, F., Caño Velasco, J., Moralejo Garate, M., Subirá Rios, D., Barbas Bernardos, G., Mayor de Castro, J., Aragón Chamizo, J., Husilllos Alonso, A., and Hernández Fernández, C.
Published: 2020
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199. Mortality prediction model for patients with bladder urothelial tumor after radical cystectomy

Author: del Pozo Jiménez, G., Herranz Amo, F., Subirá Ríos, D., Rodríguez Fernández, E., Bueno Chomón, G., Moralejo Gárate, M., Durán Merino, R., Escribano Patiño, G., Carballido Rodríguez, J., and Hernández Fernández, C.
Published: 2020
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200. Recurrence risk groups after nephrectomy for renal cell carcinoma

Author: Polanco Pujol, L., Herranz Amo, F., Caño Velasco, J., Subirá Ríos, D., Moralejo Gárate, M., Hernández Cavieres, J., Barbas Bernardos, G., Bueno Chomón, G., Rodríguez Fernández, E., and Hernández Fernández, C.
Published: 2020
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