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Objective：To explore the potential damage effects and related mechanisms of clozapine (CLP) on the heart development of zebrafish. Method：12.5 μmol/L CLP (L ⁃CLP) and 25.0 μmol/L CLP (H ⁃CLP) were used to culture zebrafish embryos for 72 hours， respectively. The heart morphology，heart rate，and the distance between venous sinus and arterial bulb (SV ⁃BA) were observed under microscope；The expression of cardiac development⁃related genes NKX2.5，Hand2 and Cmlc2 were detected by fluorescence quantitative PCR；In addition，after 24 hours of culture，the endoplasmic reticulum inhibitor 4⁃phenylbutyric acid (4⁃PBA) or dopamine D2 receptor inhibitor bromocriptine (BRC) were added to the H ⁃ CLP group for 48 hours. Then，we counted the cardiac function indicators，and detected the expression of endoplasmic reticulum stress genes (Chop、Bip) and apoptosis ⁃ related genes (Caspase3，Bax/Bcl2) . Results： CLP induced damages of cardiac structure and function in a dose⁃dependent manner，induced the expression of Chop and Bip，and further increased the expression of Caspase3 and Bax/Bcl2. 4⁃PBA and BRC significantly alleviated CLP⁃induced cardiac injury and decreased the expression levels of Chop、Bip、Caspase ⁃3 and Bax/Bcl2. Conclusion：CLP can damage the heart development of zebrafish，and the mechanism may be related to inhibiting dopamine D2 receptor and stimulating endoplasmic reticulum stress. [ABSTRACT FROM AUTHOR]

Copyright of Chinese Journal of Applied Ecology / Yingyong Shengtai Xuebao is the property of Chinese Journal of Applied Ecology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Machine Tool & Hydraulics is the property of Guangzhou Mechanical Engineering Research Institute (GMERI) and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Ecology & Rural Environment is the property of Journal of Ecology & Rural Environment Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Forest Research is the property of Forest Research Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Chinese Journal of Computational Mechanics / Jisuan Lixue Xuebao is the property of Chinese Journal of Computational Mechanics Editorial Office, Dalian University of Technology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Lubrication Engineering (0254-0150) is the property of Editorial Office of LUBRICATION ENGINEERING and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Lubrication Engineering (0254-0150) is the property of Editorial Office of LUBRICATION ENGINEERING and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Shenyang Agricultural University is the property of Journal of Shenyang Agricultural University Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Plateau Meteorology is the property of Plateau Meteorology Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Sichuan University (Medical Science Edition) is the property of Editorial Board of Journal of Sichuan University (Medical Sciences) and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Chongqing University of Technology (Natural Science) is the property of Chongqing University of Technology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Coatings & Protection / Tuceng yu Fanghu is the property of Coating & Protection Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Computer Measurement & Control is the property of Magazine Agency of Computer Measurement & Control and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Ordnance Equipment Engineering is the property of Chongqing University of Technology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Bearing is the property of Bearing Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Coal Science & Technology (0253-2336) is the property of Coal Science & Technology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Mechanical Strength / Jixie Qiangdu is the property of Zhengzhou Research Institute of Mechanical Engineering and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Control Theory & Applications / Kongzhi Lilun Yu Yinyong is the property of Editorial Department of Control Theory & Applications and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

In order to promote the high-quality development of eight cities in the Henan section of the Yellow River Basin, a high-quality development evaluation system was established for the eight cities in this region based on statistical data from 2011 to 2020. The evaluation system analyzed the development from five dimensions of green, coordinated, open, innovative and harmonious. The comprehensive entropy method was used to calculate the high-quality development index of the eight cities, and the Pearson correlation coefficient was applied to study their correlations. The results show that although the high-quality development index of the eight cities has been increasing, there are still deficiencies in the aspects of coordination and innovative development, and the indexes have not exceeded 0.800. However, the achievements in open and harmonious development are relatively balanced, and the high-quality development indexes of these cities show a positive correlation trend. In promoting high-quality development, it is necessary to focus on improving coordination and innovation, further refine development strategies and policies, and promote coordinated development in various aspects such as economy, environment, and society. [ABSTRACT FROM AUTHOR]

Objective: To investigate the correlations of age, diseases and blood pression (BP). Methods: A retrospective study was conducted to include 82 782 patients who underwent physical examination in the physical examination department of Hudong Hospital in Shanghai from January 2016 to June 2022 and met relevant criteria. Grouping according to age stages, with each stage representing 10 years, the groups are divided into ≤20 years, 21-30 years, 31-40 years, 41-50 years, 51-60 years, 61-70 years, 71-80 years, and ≥81 years. Pearson bivariate correlation method was used to analyze the correlation between BMI and systolic and diastolic blood pressure. The data were screened again and classified according to the physical examination results. The physical examination population was divided into control group and disease group, and the correlation between hypertension and disease factors was analyzed by Logistic analysis. Results: Systolic blood pressure tended to increase with age, and the level of systolic blood pressure in the group aged 61-70 was consistently higher than in the younger age groups (P < 0.01). Diastolic blood pressure also showed an increasing trend with age, with the highest levels observed between the ages of 51 and 60, followed by a significant decrease. Logistic analysis results indicated that after adjusting for age and BMI factors, metabolic syndrome had a statistically significant impact on isolated systolic blood pressure (OR = 1.068, P = 0.042). Furthermore, metabolic syndrome had a statistically significant effect on both systolic and diastolic blood pressure elevation in hypertension (OR = 1.032, P = 0.038. Conclusion: Blood pressure changes have age specificity, with systolic blood pressure showing a continuous increase with aging. Diastolic blood pressure reaches its highest value between the ages of 51 and 60, and then gradually decreases. Metabolic syndrome is associated with the occurrence of hypertension. [ABSTRACT FROM AUTHOR]

Objective A novel technique for the identification of gas-to-liquid (GTL) lubricants based on mutual information method and Bayesian algorithm is proposed to enhance the tariff identification of lubricating oils. Methods First, feature parameters of GTL lubricants and conventional petroleum lubricants are extracted, and the mutual information algorithm is used to select feature indicators with discriminative ability. Then, the Bayesian algorithm is used to model the selected feature indicators, which finally achieves the classification discrimination of GTL lubricants and conventional lubricants. Results The experimental results demonstrate the effectiveness of the proposed method in accurately discriminating between GTL lubricants and conventional petroleum lubricants. Conclusions The established model exhibits good stability and reliability, providing a comprehensive and accurate identification tool for the lubricating oil industry and tariff assessment. [ABSTRACT FROM AUTHOR]

Copyright of Piezoelectrics & Acoustooptics is the property of Piezoelectric & Acoustooptic and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Piezoelectrics & Acoustooptics is the property of Piezoelectric & Acoustooptic and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Piezoelectrics & Acoustooptics is the property of Piezoelectric & Acoustooptic and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Taiwan Agricultural Research is the property of Taiwan Agricultural Research Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Earthquake (1000-3274) is the property of Editorial Office of Earthquake Journal and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Lubrication Engineering (0254-0150) is the property of Editorial Office of LUBRICATION ENGINEERING and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Advances in Earth Science (1001-8166) is the property of Advances in Earth Science Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Electric Machines & Control / Dianji Yu Kongzhi Xuebao is the property of Electric Machines & Control and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Mechanical & Electronic Control Engineering is the property of Omniscient Pte. Ltd. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Engineering Science Research & Application is the property of Omniscient Pte. Ltd. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Education Theory & Application is the property of Omniscient Pte. Ltd. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Mechanical & Electronic Control Engineering is the property of Omniscient Pte. Ltd. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

To studied the effect of different ratio of Herba Artemisias Capillaris and Rhubarb on chlorogenic acid and anthraquinones, and to selected the best compatibility ratio, so as to provided effective reference for the development of new drugs containing "YinchenRhubarb". Three different compatibility ratios of Herba Artemisias Capillaris and Rhubarb at 1∶1, 1∶2 and 2∶1 were selected, and then Rhubarb was decocted according to Rhubarb at the same time. Part of the water decoction was selected to prepare Chlorogenic acid and anthraquinones according to the alcohol precipitation method with 70% and 80% alcohol precipitation concentration, respectively. The contents of Chlorogenic acid and anthraquinones in the supernatant and precipitation were determined by HPLC. The results showed that the content of chlorogenic acid increased after the compatibility of Artemisia Chinensis and Rhubarb, and the best compatibility ratio of water decoction and alcohol precipitation was 1∶1, and the content of chlorogenic acid extracted was 55.96 mg/mL. The content of anthraquinones also increased after the compatibility of Artemisia Chinensis and Rhubarb, in which the content of Rhein increased most significantly, and the content of Rhein extracted was 20.83 mg/mL, and the best compatibility ratio of water decoction method and water decoction and alcohol precipitation method was 1∶2. The content of Chlorogenic acid and anthraquinones increased when the compatibility ratio was 1∶1 and the ratio of anthraquinones was 1∶2 after compatibility of Herba Artemisia and Rhubarb. [ABSTRACT FROM AUTHOR]

Copyright of Feed Research is the property of Editorial Board of Feed Research and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Digitalization of rural governance is an inevitable trend of future rural governance modernization. Digital empowering rural governance is the policy practice of digital rural construction, the actual needs of solving the problem of rural governance, and a powerful proof of the feasibility of digital technology. At present, the three major areas of Shaanxi Province have made useful explorations in digital empowering rural governance, and formed a distinctive digital governance model in northern Shaanxi, Guanzhong and southern Shaanxi, and achieved many governance results, but also faced some practical problems, such as imperfect digital infrastructure of rural governance, narrow application scenarios of governance and prominent burden of digital technology. These problems restrict the improvement of the effectiveness of rural governance to a certain extent. Therefore, it is necessary to combine the actual situation of the region to solve these development problems and drive village governance of the new era with digital technology. [ABSTRACT FROM AUTHOR]

The scientific characterization of the properties of mesoporous materials is a key link for their development and application. In this paper, the development history, application scope, and characteristics of mesoporous adsorption and commonly used classical analytical models are briefly introduced by tabular comparison. To systematically understand the classical mesoporous analysis methods in physical adsorption, they were classified into four categories: modeled, model-free, completely model-free, and reverse methods. Then, these methods and three frequently-used analytical software for mesoporous adsorption were compared and analyzed. This has reference value for technicians of adsorption instrument management as well as for teaching and research of mesoporous materials. [ABSTRACT FROM AUTHOR]