Search

• Five QTLs associated with weeping traits on chromosome 7 were identified by BSR-seq. • The novel allele PmUGT72B3 has a synonymous transition of T66 (upright) to C (weeping) in the coding sequence and a 470-bp deletion in the promoter region. • PmUGT72B3 was associated with hormone and lignin regulation by WGCNA. Weeping species are used both as ornamental plants and for breeding dwarf plant types. However, exploration of casual genes controlling weeping traits is rather limited. Here, we identified individuals with contrasting phenotypes from an F1 bi-parental mapping population of Prunus mume which was developed from a cross between the upright cultivar ‘Liuban’ and the weeping cultivar ‘Fentai Chuizhi’. Bulked segregant RNA sequencing was used and five QTLs on Chromosome 7 were identified. The Pm024074 (PmUGT72B3) allele, belonging to the UDP-glycosyltransferase superfamily containing the coniferyl-alcohol glucosyltransferase domain, was identified in a genomic region overlapping with a previously identified QTL, and had a synonymous transition of T66 (upright) to C (weeping) in the coding sequence and a 470-bp deletion in the promoter region. Pm024074 had exceptionally high expression in buds and stems of weeping P. mume. Weighted correlation network analysis indicates that genes neighboring Pm024074 were significantly associated with plant architecture. In addition, a reliable single nucleotide polymorphism marker was developed based on the variation in the Pm024074 gene, providing precise marker-assisted breeding for weeping traits. This study provides insights into the genetic mechanism governing the weeping trait in P. mume, and indicates potential applications for the manipulation of tree architecture.

Laser pulses can break the electronic structure symmetry of atoms and molecules by preparing a superposition of states with different irreducible representations. Here, we discover the reverse process, symmetry restoration, by means of two circularly polarized laser pulses. The laser pulse for symmetry restoration is designed as a copy of the pulse for symmetry breaking. Symmetry restoration is achieved if the time delay is chosen such that the superposed states have the same phases at the temporal center. This condition must be satisfied with a precision of a few attoseconds. Numerical simulations are presented for the C6H6 molecule and 87Rb atom. The experimental feasibility of symmetry restoration is demonstrated by means of high-contrast time-dependent Ramsey interferometry of the 87Rb atom. [ABSTRACT FROM AUTHOR]

The article presents a study on fabrication method of metal core enhanced retention (Er) materials based on core/spacer/shell method. The thickness of spacer was increased to optimize Ag@SiO2@Y2O3:Er materials. Results indicate that upconversion emission spectra of Y2O3:2% Er has a fragile band. It show that nanostructures separated by silica shell are good model for the study of interaction of upconversion materials and metals in nanoscale.

Background: Asian women prefer a smooth and narrowed mandibular appearance. The purpose of the retrospective cohort study is to evaluate guide plate-assisted mandibular angle ostectomy (MAO) in improving mandibular symmetry for Asian female patients with mandibular angle hypertrophy (MAH) with normal occlusal relationship., Methods: We retrospectively examined 11 patients with asymmetry MAH with normal occlusal relationship who received MAO at Shanghai Ninth People's Hospital between September, 2020, and January, 2022. Preoperative plans were designed based on CT data and executed using metal guide plate during the operation. Preoperative and one-week postoperative CT scans were used to assess measurements including Height_Go, Divergence_Go, ∠ZyZy-GoGo, and osteotomy volume, to evaluate symmetry. For precision, compare the postoperative CT with the preoperative design, assessing osteotomy distance, angle, and volume error. Patient satisfacation was evaluated with Likert Scale in 6-month follow-up. Secondary lipofilling procedures were given as appropriate. Statistical analysis was performed using paired t-tests in SPSS., Results: The mean age of the 11 patients was 28.5 years (range 23-34 years). 2 of these underwent lipofilling procedures. No complications were observed during the following-up. Postoperative results were not statistically different from the design, demonstrating a precision of within 2 mm. Height_Go disparity within 5 mm get corrected notably, reducing asymmetry from 15.09% preoperatively to 2.74% postoperatively. Patients satisfaction was rated at 4.5 out of 5 in 6 month follow-up., Conclusions: Guide plate-assisted mandibular angle osteotomies achieve effective and precise surgery. This approach demonstrates a safe option for correction for mandibular asymmetry, achieving patient satisfaction., Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest., (© 2024 Han, Yichi, Kim, Sun and Chai.)

Background: Locally advanced colon cancer is considered a relative contraindication for minimally invasive proctectomy (MIP), and minimally invasive versus conventional open proctectomy (COP) for locally advanced colon cancer has not been studied., Methods: We have searched the Embase, Cochrane Library, PubMed, Medline, and Web of Science for articles on minimally invasive (robotic and laparoscopic) and COP. We calculated pooled standard mean difference (SMD), relative risk (RR), and 95% confidence intervals (CIs). The protocol for this review has been registered on PROSPERO (CRD42023407029)., Results: There are 10132 participants including 21 articles. Compared with COP, patients who underwent MIP had less operation time (SMD 0.48; CI 0.32 to 0.65; I2 = 0%, P = .000), estimated blood loss (MD -1.23; CI -1.90 to -0.56; I2 = 95%, P < .0001), the median time to semi-liquid diet (SMD -0.43; CI -0.70 to -0.15; I2 = 0%, P = .002), time to the first flatus (SMD -0.97; CI -1.30 to -0.63; I2 = 7%, P < .0001), intraoperative blood transfusion (RR 0.33; CI 0.24 to 0.46; I2 = 0%, P < .0001) in perioperative outcomes. Compared with COP, patients who underwent MIP had fewer overall complications (RR 0.85; CI 0.73 to 0.98; I2 = 22.4%, P = .023), postoperative complications (RR 0.79; CI 0.69 to 0.90; I2 = 0%, P = .001), and urinary retention (RR 0.63; CI 0.44 to 0.90; I2 = 0%, P = .011) in perioperative outcomes., Conclusion: This study comprehensively and systematically evaluated the difference between the safety and effectiveness of minimally invasive and open treatment of locally advanced colon cancer through meta-analysis. Minimally invasive proctectomy is better than COP in postoperative and perioperative outcomes. However, there is no difference in oncological outcomes. This also provides an evidence-based reference for clinical practice. Of course, multi-center RCT research is also needed to draw more scientific and rigorous conclusions in the future., Competing Interests: The authors have no conflicts of interest to disclose., (Copyright © 2024 the Author(s). Published by Wolters Kluwer Health, Inc.)

The tremendous growth in mobile devices has resulted in huge generation and usage of digital images. Image quality assessment is thus an important issue for mobile media applications. In this paper, we focus on the quality evaluation of images generated by content-aware image retargeting, in which the reference and the distorted images are of different sizes. Through retargeting, many types of deformation inconsistency lead to shape distortion, deformation artifacts, and content information loss, worsening its perceptual quality. The deformation inconsistency occurs on different levels of the retargeted images. Limited by the accuracy of the alignment between the original and retargeted images, previous methods only focus on pixel-level and patch-level fidelity analyses and fail to detect deformation inconsistency. In this paper, we improve the alignment algorithm and propose a three-level representation of the retargeting process. Based on the analysis of this three-level representation, both fidelity measures and inconsistency detection are combined to determine the final retargeting quality. The proposed algorithm is validated on the public data sets RetargetMe and CUHK. Experimental results demonstrate that inconsistency detection contributes to accurately assessing the image retargeting perceptual quality. This inspires us to investigate more about deformation inconsistency to formulate the objective quality of image retargeting.