101. Modeling the Electrical Activity of the Heart via Transfer Functions and Genetic Algorithms.
- Author
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Rodríguez-Abreo, Omar, Cruz-Fernandez, Mayra, Fuentes-Silva, Carlos, Quiroz-Juárez, Mario A., and Aragón, José L.
- Subjects
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TRANSFER functions , *HEART diseases , *METAHEURISTIC algorithms , *MATHEMATICAL models , *HEART - Abstract
Although healthcare and medical technology have advanced significantly over the past few decades, heart disease continues to be a major cause of mortality globally. Electrocardiography (ECG) is one of the most widely used tools for the detection of heart diseases. This study presents a mathematical model based on transfer functions that allows for the exploration and optimization of heart dynamics in Laplace space using a genetic algorithm (GA). The transfer function parameters were fine-tuned using the GA, with clinical ECG records serving as reference signals. The proposed model, which is based on polynomials and delays, approximates a real ECG with a root-mean-square error of 4.7% and an R 2 value of 0.72 . The model achieves the periodic nature of an ECG signal by using a single periodic impulse input. Its simplicity makes it possible to adjust waveform parameters with a predetermined understanding of their effects, which can be used to generate both arrhythmic patterns and healthy signals. This is a notable advantage over other models that are burdened by a large number of differential equations and many parameters. [ABSTRACT FROM AUTHOR]
- Published
- 2024
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