101. Bone Marrow Aspirrration Vs Bone Marrow Trephine Biopsy in Dignosis of Aplastic Anemia.
- Author
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Kotwal, Shalija and Koul, K. K.
- Subjects
- *
BONE marrow , *APLASTIC anemia , *BIOPSY , *RETICULOCYTES , *HEMATOLOGY - Abstract
The current study was conducted to evaluate the efficacy of bone marrow trephine biopsy and Bone marrow aspiration in diagnosis of aplastic anemia. This cross sectional study was done in Department of Pathology for a period of 10 years. A total of 78 cases were enrolled in the study. After proper history and physical examination, patients were subjected to detailed haematological examination. Severity of aplastic anemia was defined on the basis of peripheral blood picture, trephine biopsy and corrected reticulocyte count. A total of 78 cases were included, 61.5% were male and 38.5% were female patients. There was bimodal age of presentation but the most common affected age group was in 11-20 years. Peripheral blood smears showed normocytic, normochromic blood picture in 67.9%. Macrocytic predominance was seen in 21.8%. 50.6 % had severe aplastic anemia and 49.3% were having non severe aplastic anemia. Majority of bone marrow aspirates 85.3% correlated with bone marrow trephine biopsy. Aplastic anemia is seen in all age groups. Bone marrow trephine biopsy is superior to bone marrow aspirate in patients especially where marrow particles show variable cellularity. [ABSTRACT FROM AUTHOR]
- Published
- 2018