101. Cell Surface ABP1-TMK Auxin-Sensing Complex Activates ROP GTPase Signaling
- Author
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Wuyi Wang, Riet De Rycke, Ning Dai, Hongjiang Li, Jiří Friml, Hana Rakusová, Zimin Zhou, Alan M. Jones, Min Cao, Sara E. Patterson, Tongda Xu, Jisheng Chen, Xu Chen, Anthony B. Bleecker, Shingo Nagawa, and Zhenbiao Yang
- Subjects
rho GTP-Binding Proteins ,0106 biological sciences ,Arabidopsis ,Receptors, Cell Surface ,GTPase ,Biology ,01 natural sciences ,03 medical and health sciences ,Auxin ,Cytoskeleton ,Plant Proteins ,030304 developmental biology ,chemistry.chemical_classification ,0303 health sciences ,Multidisciplinary ,Indoleacetic Acids ,Kinase ,Cell Membrane ,biology.organism_classification ,Transmembrane protein ,Cell biology ,Plant Leaves ,chemistry ,Biochemistry ,Cytoplasm ,Signal transduction ,Protein Kinases ,Signal Transduction ,010606 plant biology & botany - Abstract
A Different Route The plant hormone auxin regulates a variety of developmental processes and responses to environmental inputs, often via changes in gene transcription. Xu et al. (p. 1025 ) analyzed a signaling pathway involving ABP1 (auxin-binding protein 1) that affects the cytoskeleton and endocytosis in Arabidopsis without changing gene transcription. Instead, ABP1 functions at the cell surface to bind auxin and a family of membrane kinases, thereby activating intracellular guanosine triphosphatases to initiate important developmental changes in cell shape.
- Published
- 2014