Search

Your search keyword '"Zhai, Yue"' showing total 771 results
Start Over Author "Zhai, Yue"
771 results on '"Zhai, Yue"'

107. Unveiling Urban Regeneration Risks in China: A Social Perspective.

Author

Xie, Hong, Zheng, Saina, Zhai, Yue, Yuan, Jingfeng, and Li, Qiming

Abstract

China's urbanization process is currently in a transition phase from rapid growth to slow growth, necessitating the implementation of sustainable measures in urban planning. Urban regeneration (UR), being one of the fundamental mechanisms for achieving sustainable urban development, has received considerable attention. UR promotes sustainable development by reusing abandoned land and buildings, improving energy efficiency, and enhancing the ecological environment. However, UR involves numerous stakeholders who may have conflicting interests due to factors such as the environment, technology, and economy, thereby giving rise to social risks (SRs). These SRs pose a threat to the success of UR projects and can also lead to social instability, as well as hindering sustainable urban development. Identifying risk sources forms the foundation of and key to risk management. Therefore, this research employs an integrated qualitative and quantitative method to explore the SR factors (SRFs) related to UR for China. On the basis of the grounded theory method, case study examination was used for data collection, resulting in the identification of 22 specific categories and five main categories. Through quantitative analysis, the identified SRFs and five main classifications of UR in China were verified, namely the negative effects of demolition and relocation, the negative environmental effect, the negative effect of technology, the organization-related negative effect, and the negative effect of policy. Among them, the unfair compensation for demolition and relocation has the greatest impact on the SRs in UR. Based on further analysis of the quantitative results, this study proposes three measures to alleviate the UR-related SRs for China on the macro, meso, and micro levels, which include improving policy and the legal system, enhancing collaborative governance capacity, and strengthening public participation. This research also has reference value in the context of promoting UR for other developing countries. [ABSTRACT FROM AUTHOR]

Published
2024
Full Text
View/download PDF

108. Place of Concordance-Discordance Model in Evaluating Next-Generation Sequencing Performance.

Author

Zhai, Yue, Bardel, Claire, Vallée, Maxime, Iwaz, Jean, and Roy, Pascal

Subjects
ERROR probability, CONDITIONAL probability, SMOOTHNESS of functions, SENSITIVITY & specificity (Statistics), NUCLEOTIDE sequencing, ERROR rates, NOMOGRAPHY (Mathematics)
Abstract

Introduction: Ideally, evaluating next-generation sequencing performance requires a gold standard; in its absence, concordance between replicates is often used as substitute standard. However, the appropriateness of the concordance-discordance criterion has been rarely evaluated. This study analyses the relationship between the probability of discordance and the probability of error under different conditions. Methods: This study used a conditional probability approach under conditional dependence then conditional independence between two sequencing results and compares the probabilities of discordance and error in different theoretical conditions of sensitivity, specificity, and correlation between replicates, then on real results of sequencing genome NA12878. The study examines also covariate effects on discordance and error using generalized additive models with smooth functions. Results: With 99% sensitivity and 99.9% specificity under conditional independence, the probability of error for a positive concordant pair of calls is 0.1%. With additional hypotheses of 0.1% prevalence and 0.9 correlation between replicates, the probability of error for a positive concordant pair is 47.4%. With real data, the estimated sensitivity, specificity, and correlation between tests for variants are around 98.98%, 99.996%, and 93%, respectively, and the error rate for positive concordant calls approximates 2.5%. In covariate effect analyses, the effects' functional form is close between discordance and error models, though the parts of deviance explained by the covariates differ between discordance and error models. Conclusion: With conditional independence of two sequencing results, the concordance-discordance criterion seems acceptable as substitute standard. However, with high correlation, the criterion becomes questionable because a high percentage of false concordant results appears among concordant results. [ABSTRACT FROM AUTHOR]

Published
2024
Full Text
View/download PDF

111. P‐17.2: Structure Design and Optical Performance Research of Automotive Oversized Curved Mini LED Module

Author

Leng, Shouyang, primary, Zhai, Yue, additional, Cui, Dong, additional, Li, Wenyang, additional, Wang, Fengping, additional, Chi, Weining, additional, Qi, Yongle, additional, Zhang, Zhipeng, additional, Tian, Yinong, additional, You, Mei, additional, Yu, Jie, additional, Han, Rui, additional, Ma, Qing, additional, Yoon, Dae-keun, additional, and Cai, Site, additional

Published
2023
Full Text
View/download PDF

114. Cysteine carboxyethylation generates neoantigens to induce HLA-restricted autoimmunity

Author

Zhai, Yue, primary, Chen, Liang, additional, Zhao, Qian, additional, Zheng, Zhao-Hui, additional, Chen, Zhi-Nan, additional, Bian, Huijie, additional, Yang, Xu, additional, Lu, Huan-Yu, additional, Lin, Peng, additional, Chen, Xi, additional, Chen, Ruo, additional, Sun, Hao-Yang, additional, Fan, Lin-Ni, additional, Zhang, Kun, additional, Wang, Bin, additional, Sun, Xiu-Xuan, additional, Feng, Zhuan, additional, Zhu, Yu-Meng, additional, Zhou, Jian-Sheng, additional, Chen, Shi-Rui, additional, Zhang, Tao, additional, Chen, Si-Yu, additional, Chen, Jun-Jie, additional, Zhang, Kui, additional, Wang, Yan, additional, Chang, Yang, additional, Zhang, Rui, additional, Zhang, Bei, additional, Wang, Li-Juan, additional, Li, Xiao-Min, additional, He, Qian, additional, Yang, Xiang-Min, additional, Nan, Gang, additional, Xie, Rong-Hua, additional, Yang, Liu, additional, Yang, Jing-Hua, additional, and Zhu, Ping, additional

Published
2023
Full Text
View/download PDF

120. Optimized Design of a Pump Laser System for a Spin Exchange Relaxation Free Inertial Measurement Device

Author

Jian Hao, Hong-Liang Ke, Zhai-Yue Yang, and Bang-Cheng Han

Subjects
square wave modulation, stability control of power, beam shaping design, freeform surface lens, Chemical technology, TP1-1185
Abstract

In order to improve the precision and beam quality of a pump laser for a spin exchange relaxation free inertial measurement device, we applied one scheme to achieve the square wave modulation and power stability control of the pump laser and another one to obtain the uniform intensity distribution of the laser beam, in which the acousto-optic modulator (AOM) and proportion integration differentiation (PID) controller were used to achieve the former, and the freeform surface lens was designed and optimized to achieve the latter based on the TracePro software. In experiments, the first-order diffraction light beam coming through the AOM had a spot size of about 1.1 × 0.7 mm2, and a spherical vapor cell with a radius of 7 mm was placed behind the freeform surface lens. Results show that the uniformity of the reshaped intensity distribution is higher than 90% within the target area with a radius of 7 mm both in the simulation and the experiment, which ensure that the uniform laser beam covers the area of cell. On the other hand, the power stability of the pump laser is controlled to be less than 0.05%. Compared with traditional methods, the complicated calculation process in optical design is better solved, and a higher uniformity with slight energy loss is achieved.

Published
2021
Full Text
View/download PDF

124. Lead exposure suppresses the Wnt3a/β-catenin signaling to increase the quiescence of hematopoietic stem cells via reducing the expression of CD70 on bone marrow-resident macrophages.

Author

Zhao, Yifan, Wu, Jiaojiao, Xu, Hua, Li, Qian, Zhang, Yufan, Zhai, Yue, Tang, Mengke, Liu, Yalin, Liu, Ting, Ye, Yao, He, Miao, He, Rui, Xu, Yanyi, Zhou, Zhou, Kan, Haidong, and Zhang, Yubin

Subjects
HEMATOPOIETIC stem cells, LEAD exposure, WNT signal transduction, BONE marrow, CORD blood, MACROPHAGES, LEAD, HUMAN ecology
Abstract

Lead (Pb) is a heavy metal highly toxic to human health in the environment. The aim of this study was to investigate the mechanism of Pb impact on the quiescence of hematopoietic stem cells (HSC). WT C57BL/6 (B6) mice treated with 1250 ppm Pb via drinking water for 8 weeks had increased the quiescence of HSC in the bone marrow (BM), which was caused by the suppressed activation of the Wnt3a/β-catenin signaling. Mechanically, a synergistic action of Pb and IFNγ on BM-resident macrophages (BM-Mφ) reduced their surface expression of CD70, which thereby dampened the Wnt3a/β-catenin signaling to suppress the proliferation of HSC in mice. In addition, a joint action of Pb and IFNγ also suppressed the expression of CD70 on human Mφ to impair the Wnt3a/β-catenin signaling and reduce the proliferation of human HSC purified from umbilical cord blood of healthy donors. Moreover, correlation analyses showed that the blood Pb concentration was or tended to be positively associated with the quiescence of HSC, and was or tended to be negatively associated with the activation of the Wnt3a/β-catenin signaling in HSC in human subjects occupationally exposed to Pb. Collectively, these data indicate that an occupationally relevant level of Pb exposure suppresses the Wnt3a/β-catenin signaling to increase the quiescence of HSC via reducing the expression of CD70 on BM-Mφ in both mice and humans. [ABSTRACT FROM AUTHOR]

Published
2023
Full Text
View/download PDF

142. Identification of MRAP protein family as broad‐spectrum GPCR modulators

Author

Wang, Meng, primary, Wang, Xiaozhu, additional, Jiang, Bopei, additional, Zhai, Yue, additional, Zheng, Jihong, additional, Yang, Liu, additional, Tai, Xiaolu, additional, Li, Yunpeng, additional, Fu, Shaliu, additional, Xu, Jing, additional, Lei, Xiaowei, additional, Kuang, Zhe, additional, Zhang, Cong, additional, Bai, Xuanxuan, additional, Li, Mingyu, additional, Zan, Tao, additional, Qu, Shen, additional, Li, Qingfeng, additional, and Zhang, Chao, additional

Published
2022
Full Text
View/download PDF

144. Lead suppresses interferon γ to induce splenomegaly via modification on splenic endothelial cells and lymphoid tissue organizer cells in mice

Author

Zhai, Yue, primary, Zhao, Yifan, additional, Zhang, Yufan, additional, He, Jinyi, additional, Tang, Mengke, additional, Liu, Yalin, additional, Yang, Guangrui, additional, Xue, Peng, additional, Yao, Ye, additional, He, Miao, additional, Xu, Yanyi, additional, Qu, Weidong, additional, and Zhang, Yubin, additional

Published
2022
Full Text
View/download PDF

146. Single-cell profiling of peripheral neuroblastic tumors identifies an aggressive transitional state that bridges an adrenergic-mesenchymal trajectory

Author

Yuan, Xiaojun, primary, Seneviratne, Janith A., additional, Du, Shibei, additional, Xu, Ying, additional, Chen, Yijun, additional, Jin, Qianya, additional, Jin, Xuanxuan, additional, Balachandran, Anushree, additional, Huang, Shihao, additional, Xu, Yanli, additional, Zhai, Yue, additional, Lu, Liumei, additional, Tang, Mengjie, additional, Dong, Yushuang, additional, Cheung, Belamy B., additional, Marshall, Glenn M., additional, Shi, Weiyang, additional, Carter, Daniel R., additional, and Zhang, Chao, additional

Published
2022
Full Text
View/download PDF

147. Facile Entropy-Driven Segregation of Imprinted Polymer-Grafted Nanoparticle Brush Blends by Solvent Vapor Annealing Soft Lithography

Author

Wu, Wenjie, primary, Singh, Maninderjeet, additional, Zhai, Yue, additional, Masud, Ali, additional, Tonny, Wafa, additional, Yuan, Chuqing, additional, Yin, Rongguan, additional, Al-Enizi, Abdullah M., additional, Bockstaller, Michael R., additional, Matyjaszewski, Krzysztof, additional, Douglas, Jack F., additional, and Karim, Alamgir, additional

Published
2022
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results