135 results on '"Zernotti, Mario"'
Search Results
102. 151 International Survey on the Management of Allergic Rhinitis by Physicians and Patients (ISMAR)
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Teijeiro, Alvaro, primary, Badellino, H. A., additional, Gomez, R. M., additional, Zernotti, Mario, additional, Croce, J. S., additional, Murrieta-Aguttes, M., additional, and Baena-Cagnani, Carlos E., additional
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- 2012
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103. 150 International Survey on the Management of Allergic Rhinitis by Physicians and Patients (ISMAR). Physiciansʼ View
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Badellino, H. A., primary, Teijeiro, Alvaro, additional, Gomez, R. M., additional, Zernotti, Mario, additional, Croce, J. S., additional, Murrieta-Aguttes, M., additional, and Baena-Cagnani, Carlos E., additional
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- 2012
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104. 181 Olfactory Disfunctions in Patients with Chronic Rhinosinusitis
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Sánchez Vallecillo, María Victoria, primary, Fraire, María Emilia, additional, Baena-Cagnani, Carlos E., additional, and Zernotti, Mario, additional
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- 2012
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105. 373 Alteration of Smell in Patients with Persistent Allergic Rhinitis
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De Barayazarra, Susana, primary, Corelli, S, additional, Cornaglia, S, additional, Zanacchi, A, additional, Sosa, S, additional, Herrera, E, additional, Teijeiro, Alvaro, additional, Canonica, Giorgio Walter, additional, Baena-Cagnani, Carlos E., additional, and Zernotti, Mario, additional
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- 2012
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106. 237 International Survey on the Management of Allergic Rhinitis by Physicians and Patients (ISMAR)
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Gomez, R. M., primary, Teijeiro, Alvaro, additional, Badellino, H. A., additional, Zernotti, Mario, additional, Murrieta-Aguttes, M., additional, and Baena-Cagnani, Carlos E., additional
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- 2012
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107. Olfactory Dysfunction in Patients with Chronic Rhinosinusitis
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Sánchez-Vallecillo, María V., primary, Fraire, María E., additional, Baena-Cagnani, Carlos, additional, and Zernotti, Mario E., additional
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- 2012
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108. Contribución de la tomografía computada con densitometría ósea en el diagnóstico de la otoesclerosis
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Romero Moroni, Fernando, Zernotti, Mario Emilio, Romero Moroni, Fernando, and Zernotti, Mario Emilio
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Planteo del problema: la otoesclerosis es una patología que en sus formas clínicas de hipoacusia mixta neurosensorial presenta un desafío diagnóstico no resuelto. El aporte de las imágenes no ha significado una ayuda, debido a técnicas complejas y de difícil interpretación. Se propone una técnica de medición densitométrica en tomografía computada con 10 puntos sobre la cápsula laberíntica para determinar focos de reabsorción o fijación ósea. Objetivos: determinar sensibilidad y especificidad de una nueva técnica de medición densitométrica en tomografía computada de pacientes con otoesclerosis. Material y métodos: se comparan 2 grupos. Un grupo control de 20 oídos sanos, y un grupo problema de 30 pacientes. A todos se les realiza medición de densitometría en Unidades Hounsfield (U.H.) de acuerdo a técnicas sencillas (7 a 10 puntos de medición). Resultados: en el grupo control se hallaron los siguientes valores de referencia: promedio y desviación estándar 2038+-64 U.H. en el grupo problema se hallaron valores por fuera del rango, determinándose un valor de 203 U.H. en más o menos del promedio, como valor altamente sugestivo de enfermedad (sensibilidad 80.8% y especificidad 85%)., Fil: Zernotti, Mario Emilio. Universidad Católica de Córdoba. Facultad de Ciencias de la Salud; Argentina
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- 2003
109. Rhinosinusitis in children and asthma severity
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Pawankar, Ruby, primary and Zernotti, Mario E, additional
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- 2009
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110. Tobacco smoking is a risk factor for asthma symptoms in teenagers independent of weight and antioxidant diet
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Gomez, R. Maximiliano, primary, Teijeiro, Alvaro, additional, Baena-Cagnani, Rodrigo, additional, Najo, Martin, additional, Zernotti, Mario, additional, and Baena-Cagnani, Carlos E, additional
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- 2007
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111. New perspectives in the treatment of allergic rhinitis and asthma in children
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Baena-Cagnani, Carlos E, primary, Passalacqua, Giovanni, additional, Gómez, Maximiliano, additional, Zernotti, Mario E, additional, and Canonica, G Walter, additional
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- 2007
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112. Active Bone Conduction Prosthesis: Bonebridge™.
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Zernotti, Mario E. and Sarasty, Andrea Bravo
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BONE conduction audiometry , *PROSTHETICS , *ARTIFICIAL implants - Abstract
Introduction Bone conduction implants are indicated for patients with conductive and mixed hearing loss, as well as for patients with single-sided deafness (SSD). The transcutaneous technology avoids several complications of the percutaneous bone conduction implants including skin reaction, skin growth over the abutment, and wound infection. The Bonebridge (MED-EL, Austria) prosthesis is a semi-implantable hearing system: the BCI (Bone Conduction Implant) is the implantable part that contains the Bone Conduction-Floating Mass Transducer (BC-FMT), which applies the vibrations directly to the bone; the external component is the audio processor Amadé BB (MED-EL, Austria), which digitally processes the sound and sends the information through the coil to the internal part. Bonebridge may be implanted through three different approaches: the transmastoid, the retrosigmoid, or the middle fossa approach. Objective This systematic review aims to describe the world' s first active bone conduction implant system, Bonebridge, as well as describe the surgical techniques in the three possible approaches, showing results from implant centers in the world in terms of functional gain, speech reception thresholds and word recognition scores. Data Synthesis The authors searched the MEDLINE database using the key term Bonebridge. They selected only five publications to include in this systematic review. The review analyzes 20 patients that received Bonebridge implants with different approaches and pathologies. Conclusion Bonebridge is a solution for patients with conductive/mixed hearing loss and SSD with different surgical approaches, depending on their anatomy. The system imparts fewer complications than percutaneous bone conduction implants and shows proven benefits in speech discrimination and functional gain. [ABSTRACT FROM AUTHOR]
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- 2015
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113. ARIA (Rinitis Alérgica y su Impacto en Asma). Logros en 10 años y necesidades futuras en América Latina.
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Baena-Cagnani, Carlos E., Sánchez-Borges, Mario, Zernotti, Mario E., Larenas-Linnemann, Désireé, Cruz, Álvaro A., González-Díaz, Sandra N., Ivancevich, Juan C., Aldrey-Palacios, Óscar, Sisul, Juan C., Solé, Dirceu, Cepeda, Alfonso M., Jares, Edgardo J., Gil, Mario Calvo, Valentin-Rostán, Marylin, Yáñez, Anahí, Gereda, José, Cardona-Villa, Ricardo, Rosario, Nelson, Croce, Víctor H., and Bachert, Claus
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ASTHMA ,PUBLIC health ,DISEASE prevalence ,ALLERGIC rhinitis ,HAY fever treatment ,DIAGNOSIS ,PATIENTS - Abstract
Copyright of Revista Alergia de Mexico is the property of Coleg. Mexicano de Inmunologia Clinica y Alergia A.C.; Soc. Lat. de Alergia, Asma e Inmunologia and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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- 2013
114. Actualización de rinitis alérgica y su impacto en el asma (ARIA 2008). La perspectiva latinoamericana.
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Baena Cagnani, Carlos E., Solé, Dirceu, Gonzélez Díaz, Sandra N., Zernotti, Mario E., Sisul, Juan C., Borges, Mario Sánchez, Guzmán, María Antonieta, Ivancevich, Juan C., Cepeda, Alfonso, Pérez, Noel Rodríguez, Gereda, José, Cruz, Alvaro, Croce, Víctor H., Khaltaev, Nikolai, and Bousquet, Jean
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HAY fever treatment ,INTEGRATIVE medicine ,ANTIHISTAMINES ,IMMUNOTHERAPY ,RESPIRATORY diseases ,THERAPEUTICS - Abstract
Copyright of Revista Alergia de Mexico is the property of Coleg. Mexicano de Inmunologia Clinica y Alergia A.C.; Soc. Lat. de Alergia, Asma e Inmunologia and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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- 2009
115. Testing for genetic and viral etiologies in congenital hearing loss based on a survey of cochlear implant centers: proposed HEARRING group consensus and future directions.
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Usami SI, Nishio SY, Gavilán J, Acharya A, Hagr A, Lassaletta L, Li Y, Maheshwari SS, Kameswaran M, Parzefall T, Raine C, Rak K, Selleck AM, Staecker H, Stöver T, Sugarova S, Topsakal V, Van Rompaey V, Mertens G, Volkenstein S, Völter C, Shehata-Dieler W, Zernotti ME, and Van de Heyning P
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- Humans, Cytomegalovirus Infections congenital, Cytomegalovirus Infections diagnosis, Connexins genetics, Cochlear Implants economics, Surveys and Questionnaires, Cochlear Implantation, Consensus, Practice Patterns, Physicians', Genetic Testing, Connexin 26, Hearing Loss, Sensorineural congenital, Hearing Loss, Sensorineural diagnosis, Hearing Loss, Sensorineural genetics
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Background: In cases of congenital sensorineural hearing loss, testing for genetic etiologies and congenital cytomegalovirus (cCMV) infection have become common practice., Aims/objectives: The purpose of this study is to determine which specific testing methodologies should be used and when., Material and Methods: We surveyed 20 practicing otolaryngologists across eighteen institutions in thirteen countries about their approach to cCMV, GJB2, and wider genetic testing., Results: We found 90% of respondents employ all three tests, either in routine or special cases. cCMV testing is widely used, with 95% of respondents incorporating it into their clinical practice. GJB2 testing was employed by 90%. In cases with negative GJB2 test results, a majority of respondents proceeded to wider genetic screening. Test reimbursement was also examined for each test. For cCMV testing, 63.1% reported reimbursement, 68.4% reported reimbursement for GJB2 variant testing and 52.6% reported reimbursement for wider genetic screening., Conclusions and Significance: A common approach is to perform cCMV and GJB2 testing as the first tests, followed by wider genetic testing. This study offers insight into the prevalence, methodologies, and reimbursement status of these testing methodologies across multiple hearing centers and countries. Current consensus and future directions are described based on the current survey.
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- 2024
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116. Effect of Cochlear Implant Electrode Insertion Depth on Speech Perception Outcomes: A Systematic Review.
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Breitsprecher TM, Baumgartner WD, Brown K, Dazert S, Doyle U, Dhanasingh A, Großmann W, Hagen R, Van de Heyning P, Mlynski R, Neudert M, Rajan G, Rak K, Van Rompaey V, Schmutzhard J, Volkenstein S, Völter C, Wimmer W, Zernotti M, and Weiss NM
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Objective: The suitable electrode array choice is broadly discussed in cochlear implantation surgery. Whether to use a shorter electrode length under the aim of structure preservation versus choosing a longer array to achieve a greater cochlear coverage is a matter of debate. The aim of this review is to identify the impact of the insertion depth of a cochlear implant (CI) electrode array on CI users' speech perception outcomes., Databases Reviewed: PubMed was searched for English-language articles that were published in a peer-reviewed journal from 1997 to 2022., Methods: A systematic electronic search of the literature was carried out using PubMed to find relevant literature on the impact of insertion depth on speech perception. The review was conducted according to the preferred reporting items for systematic reviews and meta-analyses guidelines of reporting. Studies in both, children and adults with pre- or postlingual hearing loss, implanted with a CI were included in this study. Articles written in languages other than English, literature reviews, meta-analyses, animal studies, histopathological studies, or studies pertaining exclusively to imaging modalities without reporting correlations between insertion depth and speech outcomes were excluded. The risk of bias was determined using the "Risk of Bias in Nonrandomized Studies of Interventions" tool. Articles were extracted by 2 authors independently using predefined search terms. The titles and abstracts were screened manually to identify studies that potentially meet the inclusion criteria. The extracted information included: the study population, type of hearing loss, outcomes reported, devices used, speech perception outcomes, insertion depth (linear insertion depth and/or the angular insertion depth), and correlation between insertion depth and the speech perception outcomes., Results: A total of 215 relevant studies were assessed for eligibility. Twenty-three studies met the inclusion criteria and were analyzed further. Seven studies found no significant correlation between insertion depth and speech perception outcomes. Fifteen found either a significant positive correlation or a positive effect between insertion depth and speech perception. Only 1 study found a significant negative correlation between insertion depth and speech perception outcomes., Conclusion: Although most studies reported a positive effect of insertion depth on speech perception outcomes, one-third of the identified studies reported no correlation. Thus, the insertion depth must be considered as a contributing factor to speech perception rather than as a major decisive criterion., Registration: This review has been registered in PROSPERO, the international prospective register of systematic reviews (CRD42021257547), available at https://www.crd.york.ac.uk/PROSPERO/., Competing Interests: None declared., (Copyright © 2023 The Authors. Published by Wolters Kluwer Health, Inc. on behalf of Otology & Neurotology, Inc.)
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- 2023
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117. QoL, CIs, QALYs, and Individualized Rehabilitation: The Clinical and Practical Benefits of Regularly Assessing the Quality of Life of Adult Cochlear Implant Recipients.
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Lassaletta L, Calvino M, Sanchez-Cuadrado I, Skarzynski PH, Cywka KB, Czajka N, Kutyba J, Tavora-Vieira D, Van de Heyning P, Mertens G, Staecker H, Humphrey B, Zernotti M, Zernotti M, Magele A, Ploder M, and Zabeu JS
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- Humans, Adult, Quality of Life, Quality-Adjusted Life Years, Treatment Outcome, Cochlear Implants, Deafness rehabilitation, Speech Perception
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This study aimed to report quality of life (QoL) scores in unilateral cochlear implant (CI) users and to generate guidance for clinicians on using QoL measures to individualize CI counselling and rehabilitation and to increase access to CIs as a mode of rehabilitation. Participants (n = 101) were unilateral CI users with single-sided deafness (SSD; n = 17), asymmetrical hearing loss (AHL; n = 26), or bilateral hearing loss (Uni; n = 58). Generic QoL was assessed via the Health Utilities Index (HUI-3), and disease-specific QoL was assessed via the Speech, Spatial, and Qualities of Hearing scale (SSQ12) and Nijmegen CI Questionnaire (NCIQ) at preimplantation and at 6 and 12 months of CI use. All groups had significantly increased HUI-3 scores at both intervals. The SSD group showed significant benefit on the SSQ12 at visit 3, the AHL group showed significant benefit on the SSQ12 and most NCIQ subdomains at both intervals, and the Uni group showed significant benefit with both tests at both intervals. Unilateral CI recipients demonstrate improved QoL within the first 12 months of device use. Regular assessment with generic and disease-specific questionnaires has the potential to play an important role in personalizing treatment and possibly in increasing access to CI provision.
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- 2023
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118. Late complication of cochlear implantation: Necrotizing meningoencephalitis.
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Zernotti M, Filiberti G, Muller J, and Zernotti M
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- Humans, Cochlear Implantation adverse effects, Cochlear Implants adverse effects, Meningoencephalitis etiology
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- 2022
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119. Two-phase survey on the frequency of use and safety of MRI for hearing implant recipients.
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van de Heyning P, Mertens G, Topsakal V, de Brito R, Wimmer W, Caversaccio MD, Dazert S, Volkenstein S, Zernotti M, Parnes LS, Staecker H, Bruce IA, Rajan G, Atlas M, Friedland P, Skarzynski PH, Sugarova S, Kuzovkov V, Hagr A, Mlynski R, Schmutzhard J, Usami SI, Lassaletta L, Gavilán J, Godey B, Raine CH, Hagen R, Sprinzl GM, Brown K, Baumgartner WD, and Karltorp E
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- Hearing, Humans, Magnetic Resonance Imaging, Magnets, Cochlear Implantation, Cochlear Implants
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Purpose: Magnetic resonance imaging (MRI) is often used to visualize and diagnose soft tissues. Hearing implant (HI) recipients are likely to require at least one MRI scan during their lifetime. However, the MRI scanner can interact with the implant magnet, resulting in complications for the HI recipient. This survey, which was conducted in two phases, aimed to evaluate the safety and performance of MRI scans for individuals with a HI manufactured by MED-EL (MED-EL GmbH, Innsbruck, Austria)., Methods: A survey was developed and distributed in two phases to HEARRING clinics to obtain information about the use of MRI for recipients of MED-EL devices. Phase 1 focused on how often MRI is used in diagnostic imaging of the head region of the cochlear implant (CI) recipients. Phase 2 collected safety information about MRI scans performed on HI recipients., Results: 106 of the 126 MRI scans reported in this survey were performed at a field strength of 1.5 T, on HI recipients who wore the SYNCHRONY CI or SYNCHRONY ABI. The head and spine were the most frequently imaged regions. 123 of the 126 scans were performed without any complications; two HI recipients experienced discomfort/pain. One recipient required reimplantation after an MRI was performed using a scanner that had not been approved for that implant. There was only one case that required surgical removal of the implant to reduce the imaging artefact., Conclusion: Individuals with either a SYNCHRONY CI or SYNCHRONY ABI from MED-EL can safely undergo a 1.5 T MRI when it is performed according to the manufacturer's safety policies and procedures., (© 2021. The Author(s).)
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- 2021
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120. Differentiation of COVID-19 signs and symptoms from allergic rhinitis and common cold: An ARIA-EAACI-GA 2 LEN consensus.
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Hagemann J, Onorato GL, Jutel M, Akdis CA, Agache I, Zuberbier T, Czarlewski W, Mullol J, Bedbrook A, Bachert C, Bennoor KS, Bergmann KC, Braido F, Camargos P, Caraballo L, Cardona V, Casale T, Cecchi L, Chivato T, Chu DK, Cingi C, Correia-de-Sousa J, Del Giacco S, Dokic D, Dykewicz M, Ebisawa M, El-Gamal Y, Emuzyte R, Fauquert JL, Fiocchi A, Fokkens WJ, Fonseca JA, Gemicioglu B, Gomez RM, Gotua M, Haahtela T, Hamelmann E, Iinuma T, Ivancevich JC, Jassem E, Kalayci O, Kardas P, Khaitov M, Kuna P, Kvedariene V, Larenas-Linnemann DE, Lipworth B, Makris M, Maspero JF, Miculinic N, Mihaltan F, Mohammad Y, Montefort S, Morais-Almeida M, Mösges R, Naclerio R, Neffen H, Niedoszytko M, O'Hehir RE, Ohta K, Okamoto Y, Okubo K, Panzner P, Papadopoulos NG, Passalacqua G, Patella V, Pereira A, Pfaar O, Plavec D, Popov TA, Prokopakis EP, Puggioni F, Raciborski F, Reijula J, Regateiro FS, Reitsma S, Romano A, Rosario N, Rottem M, Ryan D, Samolinski B, Sastre J, Solé D, Sova M, Stellato C, Suppli-Ulrik C, Tsiligianni I, Valero A, Valiulis A, Valovirta E, Vasankari T, Ventura MT, Wallace D, Wang Y, Williams S, Yorgancioglu A, Yusuf OM, Zernotti M, Bousquet J, and Klimek L
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- Consensus, Humans, SARS-CoV-2, Asthma, COVID-19, Common Cold, Rhinitis, Allergic diagnosis
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Background: Although there are many asymptomatic patients, one of the problems of COVID-19 is early recognition of the disease. COVID-19 symptoms are polymorphic and may include upper respiratory symptoms. However, COVID-19 symptoms may be mistaken with the common cold or allergic rhinitis. An ARIA-EAACI study group attempted to differentiate upper respiratory symptoms between the three diseases., Methods: A modified Delphi process was used. The ARIA members who were seeing COVID-19 patients were asked to fill in a questionnaire on the upper airway symptoms of COVID-19, common cold and allergic rhinitis., Results: Among the 192 ARIA members who were invited to respond to the questionnaire, 89 responded and 87 questionnaires were analysed. The consensus was then reported. A two-way ANOVA revealed significant differences in the symptom intensity between the three diseases (p < .001)., Conclusions: This modified Delphi approach enabled the differentiation of upper respiratory symptoms between COVID-19, the common cold and allergic rhinitis. An electronic algorithm will be devised using the questionnaire., (© 2021 European Academy of Allergy and Clinical Immunology and John Wiley & Sons Ltd.)
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- 2021
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121. ARIA-EAACI statement on asthma and COVID-19 (June 2, 2020).
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Bousquet J, Jutel M, Akdis CA, Klimek L, Pfaar O, Nadeau KC, Eiwegger T, Bedbrook A, Ansotegui IJ, Anto JM, Bachert C, Bateman ED, Bennoor KS, Berghea EC, Bergmann KC, Blain H, Bonini M, Bosnic-Anticevich S, Boulet LP, Brussino L, Buhl R, Camargos P, Canonica GW, Cardona V, Casale T, Chinthrajah S, Akdis M, Chivato T, Christoff G, Cruz AA, Czarlewski W, Del Giacco S, Du H, El-Gamal Y, Fokkens WJ, Fonseca JA, Gao Y, Gaga M, Gemicioglu B, Gotua M, Haahtela T, Halpin D, Hamelmann E, Hoffmann-Sommergruber K, Humbert M, Ilina N, Ivancevich JC, Joos G, Khaitov M, Kirenga B, Knol EF, Ko FW, Koskinen S, Kowalski ML, Kraxner H, Kudlay D, Kuna P, Kupczyk M, Kvedariene V, Abdul Latiff AH, Le LT, Levin M, Larenas-Linnemann D, Louis R, Masjedi MR, Melén E, Mihaltan F, Milenkovic B, Mohammad Y, Morais-Almeida M, Mullol J, Namazova L, Neffen H, Nunes E, O'Byrne P, O'Hehir R, O'Mahony L, Ohta K, Okamoto Y, Onorato GL, Panzner P, Papadopoulos NG, Passalacqua G, Patella V, Pawankar R, Pham-Thi N, Pigearias B, Popov TA, Puggioni F, Regateiro FS, Rolla G, Rottem M, Samolinski B, Sastre J, Schwarze J, Sheikh A, Scichilone N, Soto-Quiros M, Soto-Martinez M, Sova M, Nicola S, Stelmach R, Suppli-Ulrik C, Taborda-Barata L, To T, Tomazic PV, Toppila-Salmi S, Tsiligianni I, Usmani O, Valiulis A, Ventura MT, Viegi G, Vontetsianos T, Wang Y, Williams S, Wong GWK, Yorgancioglu A, Zernotti M, Zidarn M, Zuberbier T, and Agache I
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- Angiotensin-Converting Enzyme 2 physiology, Asthma drug therapy, Humans, Asthma complications, COVID-19 etiology, SARS-CoV-2
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- 2021
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122. Active smoking effect in allergic rhinitis.
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Gómez RM, Croce VH, Zernotti ME, and Muiño JC
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Background: Tobacco smoke has been described as causing increased prevalence of rhinitis symptoms and decreased atopy. Furthermore, these nasal symptoms and quality of life in smokers with Allergic Rhinitis (AR) were not significantly different to non-smokers. As a result of this duality, a comparison study between the quality of life and inflammatory markers of atopy among active smokers and non-smokers having AR was put forward., Material and Methods: Cross-sectional study in adult smokers and non-smokers, with a clinical diagnosis of AR and positive Skin Prick Test (SPT). Smoking status was confirmed by salivary cotinine measurements. Functional respiratory evaluation was performed, and quality of life between groups was compared using Mini-RQLQ questionnaire. Immunological markers in serum and nasal washes (IgE, IL-4, IL 5, IL 13, IL 17, IL 33) were evaluated, while samples from a third group of passive smokers was incorporated for serological comparison exclusively. The statistical analysis included Student T test, x2, Mann Whitney U (Anova 2-way), and Kruskal Wallis for 3 groups analysis. Values of P < 0.05 were considered significant., Results: Twenty-two patients per group with similar demographics and allergen sensitivity were studied. Regarding inflammatory markers, a reduction of IL 33 in the serum of smokers (P < 0.001) was the only statistically significant different parameter revealed, showing a remarkable trend in nasal lavage. Salivary cotinine levels were absolutely different (P < 0.0001), but pulmonary function evaluations were not statistically significant after multiple adjusting. There were no significant differences in quality of life parameters., Conclusions: In our study of AR, active smokers do not demonstrate impaired nasal related quality of life or impact on atopic inflammatory parameters, compared to non-smokers. Reduced levels of IL33 could explain a lack of symptoms alerting smokers of the harmful consequences of smoking., Competing Interests: RM Gómez, VH Croce, ME Zernotti and JC Muiño declare to have no conflict of interest regarding present study., (© 2021 The Authors.)
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- 2021
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123. ARIA digital anamorphosis: Digital transformation of health and care in airway diseases from research to practice.
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Bousquet J, Anto JM, Bachert C, Haahtela T, Zuberbier T, Czarlewski W, Bedbrook A, Bosnic-Anticevich S, Walter Canonica G, Cardona V, Costa E, Cruz AA, Erhola M, Fokkens WJ, Fonseca JA, Illario M, Ivancevich JC, Jutel M, Klimek L, Kuna P, Kvedariene V, Le L, Larenas-Linnemann DE, Laune D, Lourenço OM, Melén E, Mullol J, Niedoszytko M, Odemyr M, Okamoto Y, Papadopoulos NG, Patella V, Pfaar O, Pham-Thi N, Rolland C, Samolinski B, Sheikh A, Sofiev M, Suppli Ulrik C, Todo-Bom A, Tomazic PV, Toppila-Salmi S, Tsiligianni I, Valiulis A, Valovirta E, Ventura MT, Walker S, Williams S, Yorgancioglu A, Agache I, Akdis CA, Almeida R, Ansotegui IJ, Annesi-Maesano I, Arnavielhe S, Basagaña X, D Bateman E, Bédard A, Bedolla-Barajas M, Becker S, Bennoor KS, Benveniste S, Bergmann KC, Bewick M, Bialek S, E Billo N, Bindslev-Jensen C, Bjermer L, Blain H, Bonini M, Bonniaud P, Bosse I, Bouchard J, Boulet LP, Bourret R, Boussery K, Braido F, Briedis V, Briggs A, Brightling CE, Brozek J, Brusselle G, Brussino L, Buhl R, Buonaiuto R, Calderon MA, Camargos P, Camuzat T, Caraballo L, Carriazo AM, Carr W, Cartier C, Casale T, Cecchi L, Cepeda Sarabia AM, H Chavannes N, Chkhartishvili E, Chu DK, Cingi C, Correia de Sousa J, Costa DJ, Courbis AL, Custovic A, Cvetkosvki B, D'Amato G, da Silva J, Dantas C, Dokic D, Dauvilliers Y, De Feo G, De Vries G, Devillier P, Di Capua S, Dray G, Dubakiene R, Durham SR, Dykewicz M, Ebisawa M, Gaga M, El-Gamal Y, Heffler E, Emuzyte R, Farrell J, Fauquert JL, Fiocchi A, Fink-Wagner A, Fontaine JF, Fuentes Perez JM, Gemicioğlu B, Gamkrelidze A, Garcia-Aymerich J, Gevaert P, Gomez RM, González Diaz S, Gotua M, Guldemond NA, Guzmán MA, Hajjam J, Huerta Villalobos YR, Humbert M, Iaccarino G, Ierodiakonou D, Iinuma T, Jassem E, Joos G, Jung KS, Kaidashev I, Kalayci O, Kardas P, Keil T, Khaitov M, Khaltaev N, Kleine-Tebbe J, Kouznetsov R, Kowalski ML, Kritikos V, Kull I, La Grutta S, Leonardini L, Ljungberg H, Lieberman P, Lipworth B, Lodrup Carlsen KC, Lopes-Pereira C, Loureiro CC, Louis R, Mair A, Mahboub B, Makris M, Malva J, Manning P, Marshall GD, Masjedi MR, Maspero JF, Carreiro-Martins P, Makela M, Mathieu-Dupas E, Maurer M, De Manuel Keenoy E, Melo-Gomes E, Meltzer EO, Menditto E, Mercier J, Micheli Y, Miculinic N, Mihaltan F, Milenkovic B, Mitsias DI, Moda G, Mogica-Martinez MD, Mohammad Y, Montefort S, Monti R, Morais-Almeida M, Mösges R, Münter L, Muraro A, Murray R, Naclerio R, Napoli L, Namazova-Baranova L, Neffen H, Nekam K, Neou A, Nordlund B, Novellino E, Nyembue D, O'Hehir R, Ohta K, Okubo K, Onorato GL, Orlando V, Ouedraogo S, Palamarchuk J, Pali-Schöll I, Panzner P, Park HS, Passalacqua G, Pépin JL, Paulino E, Pawankar R, Phillips J, Picard R, Pinnock H, Plavec D, Popov TA, Portejoie F, Price D, Prokopakis EP, Psarros F, Pugin B, Puggioni F, Quinones-Delgado P, Raciborski F, Rajabian-Söderlund R, Regateiro FS, Reitsma S, Rivero-Yeverino D, Roberts G, Roche N, Rodriguez-Zagal E, Rolland C, Roller-Wirnsberger RE, Rosario N, Romano A, Rottem M, Ryan D, Salimäki J, Sanchez-Borges MM, Sastre J, Scadding GK, Scheire S, Schmid-Grendelmeier P, Schünemann HJ, Sarquis Serpa F, Shamji M, Sisul JC, Sofiev M, Solé D, Somekh D, Sooronbaev T, Sova M, Spertini F, Spranger O, Stellato C, Stelmach R, Thibaudon M, To T, Toumi M, Usmani O, Valero AA, Valenta R, Valentin-Rostan M, Pereira MU, van der Kleij R, Van Eerd M, Vandenplas O, Vasankari T, Vaz Carneiro A, Vezzani G, Viart F, Viegi G, Wallace D, Wagenmann M, Wang Y, Waserman S, Wickman M, Williams DM, Wong G, Wroczynski P, Yiallouros PK, Yusuf OM, Zar HJ, Zeng S, Zernotti ME, Zhang L, Shan Zhong N, and Zidarn M
- Subjects
- Humans, Asthma, Respiration Disorders, Rhinitis, Allergic
- Abstract
Digital anamorphosis is used to define a distorted image of health and care that may be viewed correctly using digital tools and strategies. MASK digital anamorphosis represents the process used by MASK to develop the digital transformation of health and care in rhinitis. It strengthens the ARIA change management strategy in the prevention and management of airway disease. The MASK strategy is based on validated digital tools. Using the MASK digital tool and the CARAT online enhanced clinical framework, solutions for practical steps of digital enhancement of care are proposed., (© 2020 EAACI and John Wiley and Sons A/S. Published by John Wiley and Sons Ltd.)
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- 2021
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124. [Post- stapedectomy tinnitus´ perception. Experience in a university hospital]
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Moyano ML and Zernotti ME
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- Adult, Female, Hospitals, University, Humans, Longitudinal Studies, Male, Middle Aged, Otosclerosis complications, Prospective Studies, Tinnitus etiology, Treatment Outcome, Otosclerosis surgery, Stapes Surgery, Tinnitus surgery
- Abstract
Introduccion: La otosclerosis es un trastorno de remodelación ósea caracterizada por disminución de la movilidad del estribo, lo que se traduce en una pérdida auditiva y tinnitus. El tratamiento mas comúnmente utilizado y mas eficaz es la cirugía. El objetivo principal es una mejora significativa en la pérdida auditiva, pero la reducción del tinnitus es un beneficio adicional., Objetivos: Determinar los cambios en la sensación del tinnitus después de la estapedectomía en pacientes con otosclerosis operados en nuestro medio; así también como los factores que podrían asociarse con dichos cambios., Materiales Y Metodos: Realizamos un estudio prospectivo, observacional, analítico y longitudinal, en el que se incluyeron 15 pacientes con otosclerosis operados en el Sanatorio que se sometieron a un examen completo con Audiometría, Acúfenometría y Tomografía computada; se recopilaron datos mediante la Escala de Impresión Clínica Global y el Indice Funcional del Tinnitus, al momento previo a la cirugía y a los tres meses de intervenidos. Se utilizó el Soft R- medic e Infostat para analizar las variables y graficar los resultados., Resultados: Las diferencias entre el estado de audición pre y postoperatoria fueron estadisticamente significativas (p<<0.001). Se comprobó además, diferencias estadísticamente significativas entre la percepción del tinnitus antes y despues de la cirugía (p<<0.001). Y que dicha diferencia se relaciona estadíticamente con la mejoría de la audición (p=0.01)., Discusion- Conclusion: La mayoría de los pacientes refirieron una mejoría en el estado de percepción del acúfeno; además de la mejoría en su audición; resultando en asociación significativa ambas variables., (Universidad Nacional de Córdoba)
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- 2020
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125. [Executive Summary of ARIA 2019: Integrated care pathways for allergic rhinitis in Argentina, Spain and Mexico].
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Ivancevich JC, Cardona V, Larenas-Linnemann D, Mullol J, Neffen H, Zernotti M, Asayag E, Blua AE, Gómez RM, Jares E, Máspero J, Anto JM, Dedeu T, Rodríguez-González M, Huerta-Villalobos YR, Fuentes-Pérez JM, Rodríguez-Zagal E, Valero A, Bartra J, Alobid I, Castillo-Vizuete JA, Dordal T, Hijano R, Picado C, Sastre J, Bedolla-Barajas M, Burguete-Cabañas MT, Costa-Domínguez MDC, Domínguez-Silva M, Espinoza-Contreras JG, Gálvez-Romero JL, García-Cobas CY, García-Cruz MLH, Hernández-Velázquez L, Luna-Pech JA, Matta JJ, Mogica-Martínez MD, Rivero-Yeverino D, Ruiz LT, Del Río-Navarro BE, Gómez-Vera J, Macías-Weinmann A, Agache I, Ansotegui I, Bachert C, Bedbrook A, Canonica GW, Casale TB, Cruz Á, Fokkens W, Hellings P, Samolinski B, and Bousquet J
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- Algorithms, Argentina, Critical Pathways, Humans, Mexico, Spain, Delivery of Health Care, Integrated, Rhinitis, Allergic therapy
- Abstract
The health and economic impact of allergic diseases are increasing rapidly, and changes in management strategies are required. Its influence reduces the capacity of work and school performance by at least a third. The ICPs of the airways (integrated care pathways for respiratory diseases) are structured multidisciplinary healthcare plans, promoting the recommendations of the guidelines in local protocols and their application to clinical practice. This document presents an executive summary for Argentina, Mexico, and Spain. Next-generation ARIA guidelines are being developed for the pharmacological treatment of allergic rhinitis (AR), using the GRADE-based guidelines for AR, tested with real-life evidence provided by mobile technology with visual analogue scales. It is concluded that in the AR treatment, H1-antihistamines are less effective than intranasal corticosteroids (INCS), in severe AR the INCS represent the first line of treatment, and intranasal combination INCS + anti-H1 is more effective than monotherapy. However, according to the MASK real-life observational study, patients have poor adherence to treatment and often self-medicate, according to their needs.
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- 2019
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126. Next-generation ARIA care pathways for rhinitis and asthma: a model for multimorbid chronic diseases.
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Bousquet JJ, Schünemann HJ, Togias A, Erhola M, Hellings PW, Zuberbier T, Agache I, Ansotegui IJ, Anto JM, Bachert C, Becker S, Bedolla-Barajas M, Bewick M, Bosnic-Anticevich S, Bosse I, Boulet LP, Bourrez JM, Brusselle G, Chavannes N, Costa E, Cruz AA, Czarlewski W, Fokkens WJ, Fonseca JA, Gaga M, Haahtela T, Illario M, Klimek L, Kuna P, Kvedariene V, Le LTT, Larenas-Linnemann D, Laune D, Lourenço OM, Menditto E, Mullol J, Okamoto Y, Papadopoulos N, Pham-Thi N, Picard R, Pinnock H, Roche N, Roller-Wirnsberger RE, Rolland C, Samolinski B, Sheikh A, Toppila-Salmi S, Tsiligianni I, Valiulis A, Valovirta E, Vasankari T, Ventura MT, Walker S, Williams S, Akdis CA, Annesi-Maesano I, Arnavielhe S, Basagana X, Bateman E, Bedbrook A, Bennoor KS, Benveniste S, Bergmann KC, Bialek S, Billo N, Bindslev-Jensen C, Bjermer L, Blain H, Bonini M, Bonniaud P, Bouchard J, Briedis V, Brightling CE, Brozek J, Buhl R, Buonaiuto R, Canonica GW, Cardona V, Carriazo AM, Carr W, Cartier C, Casale T, Cecchi L, Cepeda Sarabia AM, Chkhartishvili E, Chu DK, Cingi C, Colgan E, de Sousa JC, Courbis AL, Custovic A, Cvetkosvki B, D'Amato G, da Silva J, Dantas C, Dokic D, Dauvilliers Y, Dedeu A, De Feo G, Devillier P, Di Capua S, Dykewickz M, Dubakiene R, Ebisawa M, El-Gamal Y, Eller E, Emuzyte R, Farrell J, Fink-Wagner A, Fiocchi A, Fontaine JF, Gemicioğlu B, Schmid-Grendelmeir P, Gamkrelidze A, Garcia-Aymerich J, Gomez M, González Diaz S, Gotua M, Guldemond NA, Guzmán MA, Hajjam J, O'B Hourihane J, Humbert M, Iaccarino G, Ierodiakonou D, Illario M, Ivancevich JC, Joos G, Jung KS, Jutel M, Kaidashev I, Kalayci O, Kardas P, Keil T, Khaitov M, Khaltaev N, Kleine-Tebbe J, Kowalski ML, Kritikos V, Kull I, Leonardini L, Lieberman P, Lipworth B, Lodrup Carlsen KC, Loureiro CC, Louis R, Mair A, Marien G, Mahboub B, Malva J, Manning P, De Manuel Keenoy E, Marshall GD, Masjedi MR, Maspero JF, Mathieu-Dupas E, Matricardi PM, Melén E, Melo-Gomes E, Meltzer EO, Menditto E, Mercier J, Miculinic N, Mihaltan F, Milenkovic B, Moda G, Mogica-Martinez MD, Mohammad Y, Montefort S, Monti R, Morais-Almeida M, Mösges R, Münter L, Muraro A, Murray R, Naclerio R, Napoli L, Namazova-Baranova L, Neffen H, Nekam K, Neou A, Novellino E, Nyembue D, O'Hehir R, Ohta K, Okubo K, Onorato G, Ouedraogo S, Pali-Schöll I, Palkonen S, Panzner P, Park HS, Pépin JL, Pereira AM, Pfaar O, Paulino E, Phillips J, Picard R, Plavec D, Popov TA, Portejoie F, Price D, Prokopakis EP, Pugin B, Raciborski F, Rajabian-Söderlund R, Reitsma S, Rodo X, Romano A, Rosario N, Rottem M, Ryan D, Salimäki J, Sanchez-Borges MM, Sisul JC, Solé D, Somekh D, Sooronbaev T, Sova M, Spranger O, Stellato C, Stelmach R, Suppli Ulrik C, Thibaudon M, To T, Todo-Bom A, Tomazic PV, Valero AA, Valenta R, Valentin-Rostan M, van der Kleij R, Vandenplas O, Vezzani G, Viart F, Viegi G, Wallace D, Wagenmann M, Wang Y, Waserman S, Wickman M, Williams DM, Wong G, Wroczynski P, Yiallouros PK, Yorgancioglu A, Yusuf OM, Zar HJ, Zeng S, Zernotti M, Zhang L, Zhong NS, and Zidarn M
- Abstract
Background: In all societies, the burden and cost of allergic and chronic respiratory diseases are increasing rapidly. Most economies are struggling to deliver modern health care effectively. There is a need to support the transformation of the health care system into integrated care with organizational health literacy., Main Body: As an example for chronic disease care, MASK (Mobile Airways Sentinel NetworK), a new project of the ARIA (Allergic Rhinitis and its Impact on Asthma) initiative, and POLLAR (Impact of Air POLLution on Asthma and Rhinitis, EIT Health), in collaboration with professional and patient organizations in the field of allergy and airway diseases, are proposing real-life ICPs centred around the patient with rhinitis, and using mHealth to monitor environmental exposure. Three aspects of care pathways are being developed: (i) Patient participation, health literacy and self-care through technology-assisted "patient activation", (ii) Implementation of care pathways by pharmacists and (iii) Next-generation guidelines assessing the recommendations of GRADE guidelines in rhinitis and asthma using real-world evidence (RWE) obtained through mobile technology. The EU and global political agendas are of great importance in supporting the digital transformation of health and care, and MASK has been recognized by DG Santé as a Good Practice in the field of digitally-enabled, integrated, person-centred care., Conclusion: In 20 years, ARIA has considerably evolved from the first multimorbidity guideline in respiratory diseases to the digital transformation of health and care with a strong political involvement., Competing Interests: Competing interestsDr. Ansotegui reports personal fees from Mundipharma, Roxall, Sanofi, MSD, Faes Farma, Hikma, UCB, Astra Zeneca, outside the submitted work. Dr. Bosnic-Anticevich reports grants from TEVA, personal fees from TEVA, Boehringer Ingelheim, AstraZeneca, Sanofi, Mylan, outside the submitted work. Dr. Bousquet reports personal fees and others from Chiesi, Cipla, Hikma, Menarini, Mundipharma, Mylan, Novartis, Sanofi-Aventis, Takeda, Teva, Uriach, others from Kyomed, outside the submitted work. Dr. Boulet reports and Disclosure of potential conflicts of interest—last 3 years. Research grants for participation to multicentre studies, AstraZeneca, Boston Scientific, GlaxoSmithKline, Hoffman La Roche, Novartis, Ono Pharma, Sanofi, Takeda. Support for research projects introduced by the investigator AstraZeneca, Boehringer-Ingelheim, GlaxoSmithKline, Merck, Takeda. Consulting and advisory boards Astra Zeneca, Novartis, Methapharm. Royalties Co-author of “Up-To-Date” (occupational asthma). Nonprofit grants for production of educational materials AstraZeneca, Boehringer-Ingelheim, GlaxoSmithKline, Merck Frosst, Novartis. Conference fees AstraZeneca, GlaxoSmithKline, Merck, Novartis. Support for participation in conferences and meetings Novartis, Takeda. Other participations Past president and Member of the Canadian Thoracic Society Respiratory Guidelines Committee; Chair of the Board of Directors of the Global Initiative for Asthma (GINA). Chair of Global Initiative for Asthma (GINA) Guidelines Dissemination and Implementation Committee; Laval University Chair on Knowledge Transfer, Prevention and Education in Respiratory and Cardiovascular Health; Member of scientific committees for the American College of Chest Physicians, American Thoracic Society, European Respiratory Society and the World Allergy Organization; 1st Vice-President of the Global Asthma Organization “InterAsma”. Dr. Casale reports grants and non-financial support from Stallergenes, outside the submitted work. Dr. Cruz reports grants and personal fees from GlaxoSmithKline, personal fees from Boehrinher Ingelheim, AstraZeneca, Novartis, Merk, Sharp & Dohme, MEDA Pharma, EUROFARMA, Sanofi Aventis, outside the submitted work. Dr. Ebisawa reports personal fees from DBV Technologies, Mylan EPD maruho, Shionogi & CO., Ltd., Kyorin Pharmaceutical Co., Ltd., Thermofisher Diagnostics, Pfizer, Beyer, Nippon Chemifar, Takeda Pharmaceutical Co., Ltd., MSD, outside the submitted work. Dr. Ivancevich reports personal fees from Euro Farma Argentina, Faes Farma, non-financial support from Laboratorios Casasco, outside the submitted work. Dr. Haahtela reports personal fees from Mundipharma, Novartis, and Orion Pharma, outside the submitted work. Dr. Klimek reports grants and personal fees from ALK Abelló, Denmark, Novartis, Switzerland, Allergopharma, Germany, Bionorica, Germany, GSK, Great Britain, Lofarma, Italy, personal fees from MEDA, Sweden, Boehringer Ingelheim, Germany, grants from Biomay, Austria, HAL, Netherlands, LETI, Spain, Roxall, Germany, Bencard, Great Britain, outside the submitted work. V.KV has received payment for consultancy from GSK and for lectures from StallergensGreer, Berlin-CHemie and sponsorship from MYLAN for in the following professional training: ARIA masterclass in allergic rhinitis participation. Dr. Larenas Linnemann reports personal fees from GSK, Astrazeneca, MEDA, Boehringer Ingelheim, Novartis, Grunenthal, UCB, Amstrong, Siegfried, DBV Technologies, MSD, Pfizer., grants from Sanofi, Astrazeneca, Novartis, UCB, GSK, TEVA, Chiesi, Boehringer Ingelheim, outside the submitted work. Dr. Mösges reports personal fees from ALK, grants from ASIT biotech, Leti, BitopAG, Hulka, Ursapharm, Optima; personal fees from allergopharma, Nuvo, Meda, Friulchem, Hexal, Servier, Bayer, Johnson & Johnson, Klosterfrau, GSK, MSD, FAES, Stada, UCB, Allergy Therapeutics; grants and personal fees from Bencard, Stallergenes; grants, personal fees and non-financial support from Lofarma; non-financial support from Roxall, Atmos, Bionorica, Otonomy, Ferrero; personal fees and non-financial support from Novartis; Dr. Okamoto reports personal fees from Eizai Co., Ltd., Shionogi Co., Ltd., Torii Co., Ltd., GSK, MSD, Kyowa Co., Ltd., grants and personal fees from Kyorin Co., Ltd., Tiho Co., Ltd., grants from Yakuruto Co., Ltd., Yamada Bee Farm, outside the submitted work. Dr. Papadopoulos reports grants from Gerolymatos, personal fees from Hal Allergy B.V., Novartis Pharma AG, Menarini, Hal Allergy B.V., outside the submitted work. Dr. Pépin reports grants from AIR LIQUIDE FOUNDATION, AGIR à dom, ASTRA ZENECA, FISHER & PAYKEL, MUTUALIA, PHILIPS, RESMED, VITALAIRE, other from AGIR à dom, ASTRA ZENECA, BOEHRINGER INGELHEIM, JAZZ PHARMACEUTICAL, NIGHT BALANCE, PHILIPS, RESMED, SEFAM, outside the submitted work. Dr. Pfaar reports grants and personal fees from ALK-Abelló, Allergopharma Stallergenes Greer, HAL Allergy Holding B.V./HAL Allergie GmbH, Bencard Allergie GmbH/Allergy Therapeutics, Lofarma, grants from Biomay, ASIT Biotech Tools S.A, Laboratorios LETI/LETI Pharma, Anergis S.A., grants from Nuvo, Circassia, Glaxo Smith Kline, personal fees from Novartis Pharma, MEDA Pharma, Mobile Chamber Experts (a GA2LEN Partner), Pohl-Boskamp, Indoor Biotechnologies, grants from, outside the submitted work. Dr. Todo-Bom reports grants and personal fees from Novartis, Mundipharma, GSK Teva Pharma, personal fees from AstraZeneca, grants from Leti, outside the submitted work. Dr. Tsiligianni reports advisory boards from Boehringer Ingelheim and Novartis and a grant from GSK, outside the submitted work. Dr. Wallace reports and Indicates that she is the co-chair of the Joint Task Force on Practice Parameters, a task force composed of 12 members of the American Academy of Allergy, Asthma, and Immunology and the American College of Allergy, Asthma, and Immunology. Dr. Waserman reports other from CSL Behring, Shire, AstraZeneca,Teva, Meda, Merck, outside the submitted work. Dr. Zuberbier reports and Organizational affiliations: Commitee member: WHO-Initiative “Allergic Rhinitis and Its Impact on Asthma” (ARIA). Member of the Board: German Society for Allergy and Clinical Immunology (DGAKI). Head: European Centre for Allergy Research Foundation (ECARF). Secretary General: Global Allergy and Asthma European Network (GA2LEN). Member: Committee on Allergy Diagnosis and Molecular Allergology, World Allergy Organization (WAO).
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- 2019
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127. Auditory Performances in Older and Younger Adult Cochlear Implant Recipients: Use of the HEARRING Registry.
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Hofkens-Van den Brandt A, Mertens G, Gilles A, Fransen E, Lassaletta L, Gavilan J, Calvino M, Yanov Y, Kuzovkov V, Kliachko D, Zernotti M, Gregorio DMFD, Van Rompaey V, Van de Heyning P, and Sugarova S
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- Adult, Age Factors, Aged, Female, Hearing, Humans, Male, Middle Aged, Registries, Speech Perception, Young Adult, Cochlear Implantation, Cochlear Implants, Hearing Loss surgery, Treatment Outcome
- Abstract
Objective: To evaluate the hearing outcomes of cochlear implantation in different age groups by using data collected in the HEARRING registry., Methods: A multicenter study. Data of 146 patients were collected in a HEARRING registry. Patients were divided into three different age groups; ≤ 55 years old (age group 1, n = 66), 56 to 69 years old (age group 2, n = 45), and ≥ 70 years old (age group 3, n = 35). Speech in quiet (SPIQ), speech in noise (SPIN), and hearing implant sound quality index (HISQUI19) scores were evaluated for the different age groups at different test moments (preoperatively, 3, 6, 12, and 24 mo after first fitting)., Results: A statistically significant difference (p < 0.01) was found between preoperative scores and the scores on all the follow-up moments across all age groups. For SPIQ and SPIN, none of the time points showed a statistically significant age effect (p = 0.88 and p = 0.89). For HISQUI19 scores, a statistically significant age effect was found at 12 months after first fitting. The oldest age group scored significantly lower on the HISQUI19 compared with the youngest age group., Conclusion: Hearing outcomes of adult cochlear implant users of different age groups were evaluated. The SPIQ and SPIN tests showed no significant differences between the different age groups. Nevertheless, the youngest group scored significantly better on self -perceived benefit (HISQUI19) with a cochlear implant compared with the oldest age group.Further research is needed to receive more insight into cochlear implantation in the elderly and its implications on rehabilitating and supporting this expanding older population.
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- 2019
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128. [MASK (Mobile Airways Sentinel Network), a mobile App with ARIA's comprehensive solution in Spanish-speaking countries].
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Larenas-Linnemann D, Mullol J, Ivancevich JC, Anto JM, Cardona V, Dedeu T, Rodríguez-González M, Huerta-Villalobos YR, Neffen H, Fuentes-Pérez JM, Rodríguez-Zagal E, Valero A, Zernotti M, Bartra J, Alobid I, Castillo-Vizuete JA, Dordal T, Hijano R, Picado C, Sastre J, Blua AE, Jares E, Lavrut AJ, Máspero J, Bedolla-Barajas M, Burguete-Cabañas MT, Costa-Domínguez MC, Domínguez-Silva M, Espinoza-Contreras JG, Gálvez-Romero JL, García-Cobas CY, García-Cruz MLH, Hernández-Velázquez L, Luna-Pech JA, Matta JJ, Mogica-Martínez MD, Rivero-Yeverino D, Ruiz LT, Del Río-Navarro BE, Gómez-Vera J, Macías-Weinmann A, Murray R, Onorato G, Laune D, Bedbrook A, and Bousquet J
- Subjects
- Argentina, Humans, Language, Mexico, Spain, Asthma diagnosis, Asthma therapy, Mobile Applications, Rhinitis, Allergic diagnosis, Rhinitis, Allergic therapy
- Abstract
Although there are high quality clinical guidelines about allergic rhinitis, many patients receive deficient treatment, partly due to the high level of self-medication. MASK (Mobile Airways Sentinel Network) is an integral part of a project against chronic diseases which it is focused on active and healthy aging and is supported by the European Union. It forms the third phase of ARIA (Allergic Rhinitis and its Impact on Asthma) in which, through a mobile app on a smart device, the purpose is to guide patients in the control of their multimorbidity, allergic rhinitis or conjunctivitis, or asthma. The "Allergy Diary" app by MACVIA-ARIA is free and it is available for Android and iOS; on it, patients indicate how unpleasant the symptoms are on a daily basis through five screens with an analogous visual scale; two more screens were recently added (sleep affectation). With the app, it is also possible to download the information of the "Allergy Diary" on the physician's computer through a QR code at the moment of the medical consultation. In this article, we review the first year of experience in Spain, Mexico and Argentina, where the Spanish version is used.
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- 2019
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129. Hearing preservation cochlear implantation in children: The HEARRING Group consensus and practice guide.
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Rajan G, Tavora-Vieira D, Baumgartner WD, Godey B, Müller J, O'Driscoll M, Skarzynski H, Skarzynski P, Usami SI, Adunka O, Agrawal S, Bruce I, De Bodt M, Caversaccio M, Pilsbury H, Gavilán J, Hagen R, Hagr A, Kameswaran M, Karltorp E, Kompis M, Kuzovkov V, Lassaletta L, Yongxin L, Lorens A, Manoj M, Martin J, Mertens G, Mlynski R, Parnes L, Pulibalathingal S, Radeloff A, Raine CH, Rajeswaran R, Schmutzhard J, Sprinzl G, Staecker H, Stephan K, Sugarova S, Zernotti M, Zorowka P, and Van de Heyning P
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- Acoustic Stimulation methods, Child, Child, Preschool, Consensus, Correction of Hearing Impairment methods, Electric Stimulation methods, Female, Humans, Male, Cochlear Implantation standards, Cochlear Implants standards, Correction of Hearing Impairment standards, Hearing Loss rehabilitation
- Abstract
Objectives: To provide multidisciplinary cochlear implant teams with a current consensus statement to support hearing preservation cochlear implantation (HPCI) in children, including those children with symptomatic partial deafness (PD) where the intention is to use electric-acoustic stimulation (EAS). The main objectives are to provide guidelines on who is a candidate, how to assess these children and when to implant if Med-El Flex electrode arrays are chosen for implantation., Methods: The HEARRING group reviewed the current evidence and practice regarding the management of children to be considered for HPCI surgery emphasizing the assessment needed prior to implantation in order to demonstrate the benefits in these children over time. The consensus statement addresses following three key questions: (1) Should these children be treated? (2) How to identify these children? (3) How to manage these children?, Summary: The HEARRING group concludes that irrespective of the degree of residual hearing present, the concepts of hearing and structure preservation should be applied in every child undergoing cochlear implantation and that HPCI is a safe and reliable treatment option. Early detection and multidisciplinary assessment are key to the identification of children with symptomatic PD, these children should undergo HPCI as early as possible.
- Published
- 2018
- Full Text
- View/download PDF
130. Otitis media with effusion and atopy: is there a causal relationship?
- Author
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Zernotti ME, Pawankar R, Ansotegui I, Badellino H, Croce JS, Hossny E, Ebisawa M, Rosario N, Sanchez Borges M, Zhang Y, and Zhang L
- Abstract
Otitis Media with Effusion (OME) is an inflammatory condition of the middle ear cleft, acute or chronic, with collection of fluid in the middle ear with an intact tympanic membrane. It is a very common disease in childhood, the most frequent cause of hearing loss in childhood and often requiring surgery. OME is called chronic when the fluid in the middle ear persists for more than three months or when the episodes recur six or more times in one year. The current article covers various aspects of OME including definition, epidemiology. Pathomechanisms, risk factors, role of allergy in OME, impact of upper airway disease on OME, eosinophilic otitis media and management of OME.
- Published
- 2017
- Full Text
- View/download PDF
131. [ARIA 2016 executive summary: Integrated care pathways for predictive medicine throughout the life cycle in Argentina].
- Author
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Ivancevich JC, Neffen H, Zernotti ME, Asayag E, Blua A, Cicerán A, Jares EJ, Lavrut AJ, Máspero JF, Agache I, Bachert C, Bedbrook A, Canonica GW, Casale TB, Cruz ÁA, Fokkens WJ, Hellings PW, Samolinski B, and Bousquet J
- Subjects
- Argentina epidemiology, Clinical Decision-Making, Disease Management, Health Plan Implementation, Healthcare Disparities, Humans, Medical Records, Mobile Applications, Rhinitis, Allergic classification, Smartphone, Surveys and Questionnaires, User-Computer Interface, Visual Analog Scale, World Health Organization, Asthma epidemiology, Delivery of Health Care, Integrated, Rhinitis, Allergic epidemiology
- Abstract
The ARIA initiative was started during a World Health Organization workshop in 1999. The initial goals were to propose a new classification for allergic rhinitis, to promote the concept of multi-morbidity in asthma and rhinitis and to develop guidelines with stakeholders for world-wide use. ARIA is now focused on the implementation of emerging technologies for individualized and predictive medicine. MASK: MACVIA-Aria Sentinel Network uses mobile technology to develop care pathways that enable management by a multidisciplinary group or by patients themselves. An App for iOS and Android uses a visual analogue scale to assess symptom control and work productivity, as well as a clinical decision support system; it is associated with an interoperable tablet for health professionals. The escalation strategy uses recommendations of the European Innovation Partnership on Active and Healthy Ageing. The aim of ARIA's new approach is to provide an active and healthy life to people affected by rhinitis, regardless of age, gender or socioeconomic status, in order to reduce social and health inequalities caused by the disease.
- Published
- 2017
- Full Text
- View/download PDF
132. Hearing preservation and cochlear implants according to inner ear approach: multicentric evaluation.
- Author
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Guimarães AC, Carvalho GM, Duarte AS, Bianchini WA, Sarasty AB, Gregorio MF, Zernotti ME, Sartorato EL, and Castilho AM
- Subjects
- Adult, Aged, Auditory Threshold, Electric Stimulation, Female, Hearing Tests, Humans, Male, Middle Aged, Postoperative Period, Prospective Studies, Prosthesis Fitting, Round Window, Ear surgery, Speech Perception, Tympanic Membrane surgery, Young Adult, Cochlear Implantation methods, Cochlear Implants, Hearing Loss, Unilateral diagnosis, Hearing Loss, Unilateral surgery
- Abstract
Introduction: Electroacoustic stimulation is an excellent option for people with residual hearing in the low frequencies, who obtain insufficient benefit with hearing aids. To be effective, the subject's residual hearing should be preserved during cochlear implant surgery., Objectives: To evaluate the hearing preservation in patients that underwent implant placement and to compare the results in accordance with the approach to the inner ear., Methods: 19 subjects underwent a soft surgical technique, and the electrode MED-EL FLEX™ EAS, designed to be atraumatic, was used. We evaluated pre- and postoperative tonal audiometric tests with an average of 18.4 months after implantation, to measure the rate of hearing preservation., Results: 17 patients had total or partial preservation of residual hearing; 5 had total hearing preservation and two individuals had no preservation of hearing. The insertion of the electrode occurred through a cochleostomy in 3 patients, and in 2 of these there was no hearing preservation; the other 16 patients experienced electrode insertion through a round window approach. All patients benefited from the cochlear implant, even those who are only using electrical stimulation., Conclusion: The hearing preservation occurred in 89.4% of cases. There was no significant difference between the forms of inner ear approach., (Copyright © 2014 Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial. Published by Elsevier Editora Ltda. All rights reserved.)
- Published
- 2015
- Full Text
- View/download PDF
133. [Enchondroma of the mastoid secondary to generalised enchondromatosis].
- Author
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León FM, Gómez Quiroz C, and Zernotti ME
- Subjects
- Adult, Chondroma diagnostic imaging, Enchondromatosis complications, Humans, Male, Radiography, Skull Neoplasms diagnostic imaging, Chondroma etiology, Mastoid, Skull Neoplasms etiology
- Published
- 2014
- Full Text
- View/download PDF
134. [ARIA (Allergic Rhinitis and its Impact on Asthma). Achievements in 10 years and future needs in Latin America].
- Author
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Baena-Cagnani CE, Sánchez-Borges M, Zernotti ME, Larenas-Linnemann D, Cruz AA, González-Díaz SN, Ivancevich JC, Aldrey-Palacios O, Sisul JC, Solé D, Cepeda AM, Jares EJ, Calvo Gil M, Valentin-Rostán M, Yáñez A, Gereda J, Cardona-Villa R, Rosario N, Croce VH, Bachert C, Canonica GW, Demoly P, Passalacqua G, Samolinski B, Schünemann HJ, Yorgancioglu A, Ansotegui IJ, Khaltaev N, Bedbrook A, Zuberbier T, and Bousquet J
- Subjects
- Allergy and Immunology trends, Asthma classification, Asthma prevention & control, Asthma therapy, Congresses as Topic, Expert Testimony, Forecasting, Government, Health Policy, Humans, Latin America epidemiology, Phenotype, Practice Guidelines as Topic, Private Sector, Randomized Controlled Trials as Topic, Rhinitis, Allergic, Rhinitis, Allergic, Perennial classification, Rhinitis, Allergic, Perennial prevention & control, Rhinitis, Allergic, Perennial therapy, Societies, Medical trends, World Health Organization, Allergy and Immunology organization & administration, Asthma epidemiology, Health Services Needs and Demand trends, Rhinitis, Allergic, Perennial epidemiology, Societies, Medical organization & administration
- Abstract
Allergic rhinitis and asthma represent global problems of public health affecting all age groups; asthma and allergic rhinitis frequently coexist in the same patients. In Latin American prevalence of allergic rhinitis, although variable, is very high. Allergic rhinitis and its Impact on Asthma (ARIA) started during a workshop of the World Health Organization performed in 1999 and was published in 2001. ARIA proposed a new classification of allergic rhinitis in intermittent or persistent and mild or moderate-severe. This approach of classification reflects more nearly the impact of allergic rhinitis in patients. In its review of 2010 ARIA developed guidelines for diagnosis and treatment of allergic rhinitis and of clinical practices for management of comorbidities of allergic rhinitis and asthma based on GRADE (Grading of Recommendations, Development and Evaluation). ARIA has been spread and implemented in more than 50 countries. In Latin American an intense activity has been developed to spread these recommendations in almost all the countries of the region and it is important to record the obtained goals in the diffusion and implementation of ARIA, as well as to identify the unsatisfied needs from the clinical, research and implementation points of view. Final objective is to reinforce the priority that allergy and asthma should have, especially in children, in the programs of public health, as they have been prioritized in European Union in 2011.
- Published
- 2013
135. [Allergic rhinitis update and its impact on asthma (ARIA 2008). Latin American perspective].
- Author
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Cagnani CE, Solé D, Díaz SN, Zernotti ME, Sisul JC, Borges MS, Guzmán MA, Ivancevich JC, Cepeda A, Pérez NR, Gereda J, Cruz A, Croce VH, Khaltaev N, and Bousquet J
- Subjects
- Algorithms, Anti-Allergic Agents supply & distribution, Anti-Allergic Agents therapeutic use, Asthma diagnosis, Asthma therapy, Comorbidity, Developing Countries, Evidence-Based Medicine, Humans, Latin America epidemiology, Prevalence, Rhinitis, Allergic, Perennial diagnosis, Rhinitis, Allergic, Perennial therapy, Rhinitis, Allergic, Seasonal diagnosis, Rhinitis, Allergic, Seasonal therapy, Socioeconomic Factors, World Health Organization organization & administration, Asthma epidemiology, Practice Guidelines as Topic, Rhinitis, Allergic, Perennial epidemiology, Rhinitis, Allergic, Seasonal epidemiology
- Abstract
Rhinitis is the most frequent respiratory disease in most countries of the world. It is estimated that 600 million people suffer this condition. Allergic rhinitis is a public health problem at global level. Patients who suffer allergic rhinitis have from mild to annoying nasal symptoms which affect quality of life, cause sleep disorders, scholar and workplace absenteeism, and health expenditure. Rhinitis is frequently associated to co-morbidities such as sinusitis, otitis media, and especially asthma. Rhinitis is under-diagnosed and under-treated worldwide and also in Latin American countries. ARIA is the very first evidence-based guideline for the diagnosis and treatment of rhinitis with focus in its co-morbidities (2001), especially asthma published in 2001. In 2008 an update was published. ARIA recommends an integrative approach for management; including anti-histamines (second generation), intra-nasal corticosteroids, anti-leukotrienes and immunotherapy. It also provides a questionnaire to evaluate asthma and its severity in those patients suffering rhinitis. The prevalence of allergic rhinitis is quite high in Latin American countries and in recent years a great insight on the burden of this condition has been gained.
- Published
- 2009
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