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In molecular communication via diffusion (MCvD), the inter-symbol interference (ISI) is a well-known severe problem that deteriorates both data-rate and link reliability. ISI mainly occurs because of the slow and highly random propagation of the messenger molecules, which causes the emitted molecules from the previous symbols to interfere with molecules from the current symbol. An effective way to mitigate the ISI is using enzymes to degrade undesired molecules. Prior work on ISI mitigation by enzymes has assumed an infinite amount of enzymes randomly distributed around the molecular channel. Taking a different approach, this paper assumes an MCvD channel with a limited amount of enzymes. The main question this paper addresses is how to deploy these enzymes in an effective structure so that ISI mitigation is maximized. To find an effective MCvD channel environment, this study considers optimization of the shape of the transmitter node, the deployment location and structure, the size of the enzyme deployed area, and the half-lives of the enzymes. It also analyzes the dependence of the optimum size of the enzyme area on the distance and half-life. Lastly, the paper yields interesting results regarding the actual shape of the enzyme region itself. [ABSTRACT FROM AUTHOR]

Cognitive radio heralds the next step in the evolution of wireless communications. In this paper, an analytical model for infrastructure based cognitive radio systems is proposed, and its performance is evaluated under bursty traffic scenarios in a multiple cell environment. Performance metrics like probabilities of dropping and blocking for primary and secondary users as well as forced termination and forced frequency handoff for secondary users are investigated, and the analytical model is verified with simulations. In addition to the analytical model, a new resource planning method is proposed to compensate for uneven traffic load distribution. The proposed method considers offered traffic, hop count to the heavily loaded cell, and velocity of mobile users during resource planning and performs better in terms of probability of blocking, dropping, and forced termination. The proposed method is promising in balancing the system performance measures, yet there is room for further improvement for finding a closed formula for the proposed analytical model. Copyright © 2010 John Wiley & Sons, Ltd. [ABSTRACT FROM AUTHOR]