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102. Maternal exposure to ambient air pollution and congenital heart defects in China

Author

Yang, Bo-Yi, primary, Qu, Yanji, additional, Guo, Yuming, additional, Markevych, Iana, additional, Heinrich, Joachim, additional, Bloom, Michael S., additional, Bai, Zhipeng, additional, Knibbs, Luke C., additional, Li, Shanshan, additional, Chen, Gongbo, additional, Jalaludin, Bin, additional, Morawska, Lidia, additional, Gao, Meng, additional, Han, Bin, additional, Yu, Yunjiang, additional, Liu, Xiao-Xuan, additional, Ou, Yanqiu, additional, Mai, Jinzhuang, additional, Gao, Xiangmin, additional, Wu, Yong, additional, Nie, Zhiqiang, additional, Zeng, Xiao-Wen, additional, Hu, Li-Wen, additional, Shen, Xubo, additional, Zhou, Yuanzhong, additional, Lin, Shao, additional, Liu, Xiaoqing, additional, and Dong, Guang-Hui, additional

Published
2021
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103. Maternal exposure to ambient air pollution and congenital heart defects in China

Author

Yang, Bo-Yi, Qu, Yanji, Guo, Yuming, Markevych, Iana, Heinrich, Joachim, Bloom, Michael S., Bai, Zhipeng, Knibbs, Luke C., Li, Shanshan, Chen, Gongbo, Jalaludin, Bin, Morawska, Lidia, Gao, Meng, Han, Bin, Yu, Yunjiang, Liu, Xiao-xuan, Ou, Yanqiu, Mai, Jinzhuang, Gao, Xiangmin, Wu, Yong, Nie, Zhiqiang, Zeng, Xiao-Wen, Hu, Li-Wen, Shen, Xubo, Zhou, Yuanzhong, Lin, Shao, Liu, Xiaoqing, Dong, Guang-Hui, Yang, Bo-Yi, Qu, Yanji, Guo, Yuming, Markevych, Iana, Heinrich, Joachim, Bloom, Michael S., Bai, Zhipeng, Knibbs, Luke C., Li, Shanshan, Chen, Gongbo, Jalaludin, Bin, Morawska, Lidia, Gao, Meng, Han, Bin, Yu, Yunjiang, Liu, Xiao-xuan, Ou, Yanqiu, Mai, Jinzhuang, Gao, Xiangmin, Wu, Yong, Nie, Zhiqiang, Zeng, Xiao-Wen, Hu, Li-Wen, Shen, Xubo, Zhou, Yuanzhong, Lin, Shao, Liu, Xiaoqing, and Dong, Guang-Hui

Abstract

Background: Evidence of maternal exposure to ambient air pollution on congenital heart defects (CHD) has been mixed and are still relatively limited in developing countries. We aimed to investigate the association between maternal exposure to air pollution and CHD in China. Method: This longitudinal, population-based, case-control study consecutively recruited fetuses with CHD and healthy volunteers from 21 cities, Southern China, between January 2006 and December 2016. Residential address at delivery was linked to random forests models to estimate maternal exposure to particulate matter with an aerodynamic diameter of ≤1 µm (PM1), ≤2.5 µm, and ≤10 µm as well as nitrogen dioxides, in three trimesters. The CHD cases were evaluated by obstetrician, pediatrician, or cardiologist, and confirmed by cardia ultrasound. The CHD subtypes were coded using the International Classification Diseases. Adjusted logistic regression models were used to assess the associations between air pollutants and CHD and its subtypes. Results: A total of 7055 isolated CHD and 6423 controls were included in the current analysis. Maternal air pollution exposures were consistently higher among cases than those among controls. Logistic regression analyses showed that maternal exposure to all air pollutants during the first trimester was associated with an increased odds of CHD (e.g., an interquartile range [13.3 µg/m3] increase in PM1 was associated with 1.09-fold ([95% confidence interval, 1.01-1.18]) greater odds of CHD). No significant associations were observed for maternal air pollution exposures during the second trimester and the third trimester. The pattern of the associations between air pollutants and different CHD subtypes was mixed. Conclusions: Maternal exposure to greater levels of air pollutants during the pregnancy, especially the first trimester, is associated with higher odds of CHD in offspring. Further longitudinal well-designed studies are warranted to confirm our

Published
2021

104. Association of Prenatal, Early Postnatal, or Current Exposure to Secondhand Smoke With Attention-Deficit/Hyperactivity Disorder Symptoms in Children

Author

Lin, Li-Zi, primary, Xu, Shu-Li, additional, Wu, Qi-Zhen, additional, Zhou, Yang, additional, Ma, Hui-Min, additional, Chen, Duo-Hong, additional, Chen, Gong-Bo, additional, Yu, Hong-Yao, additional, Yang, Bo-Yi, additional, Zeng, Xiao-Wen, additional, Hu, Li-Wen, additional, and Dong, Guang-Hui, additional

Published
2021
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105. Short‐Term Effects of Particle Size and Constituents on Blood Pressure in Healthy Young Adults in Guangzhou, China

Author

Guo, Peng‐Yue, primary, He, Zhi‐Zhou, additional, Jalaludin, Bin, additional, Knibbs, Luke D., additional, Leskinen, Ari, additional, Roponen, Marjut, additional, Komppula, Mika, additional, Jalava, Pasi, additional, Hu, Li‐Wen, additional, Chen, Gongbo, additional, Zeng, Xiao‐Wen, additional, Yang, Bo‐Yi, additional, and Dong, Guang‐Hui, additional

Published
2021
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106. Short-Term Effects of Particle Sizes and Constituents on Blood Biomarkers among Healthy Young Adults in Guangzhou, China

Author

Feng, Dan, primary, Cao, Ke, additional, He, Zhi-Zhou, additional, Knibbs, Luke D., additional, Jalaludin, Bin, additional, Leskinen, Ari, additional, Roponen, Marjut, additional, Komppula, Mika, additional, Jalava, Pasi, additional, Guo, Peng-Yue, additional, Xu, Shu-Li, additional, Yang, Bo-Yi, additional, Hu, Liwen, additional, Zeng, Xiao-Wen, additional, Chen, Gongbo, additional, Yu, Hong-Yao, additional, Lin, Lizi, additional, and Dong, Guanghui, additional

Published
2021
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107. Perfluorooctanesulfonate and perfluorooctanoate exacerbate airway inflammation in asthmatic mice and in vitro

Author

Yang, Mo, primary, Li, Li-Yue, additional, Qin, Xiao-Di, additional, Ye, Xiao-Yan, additional, Yu, Shu, additional, Bao, Qing, additional, Sun, Lin, additional, Wang, Zhi-Bin, additional, Bloom, Michael S., additional, Jalava, Pasi, additional, Hu, Li-Wen, additional, Yu, Hong-Yao, additional, Zeng, Xiao-Wen, additional, Yang, Bo-Yi, additional, Dong, Guang-Hui, additional, and Li, Chun-Wei, additional

Published
2021
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108. Association of early life and acute pollen exposure with lung function and exhaled nitric oxide (FeNO). A prospective study up to adolescence in the GINIplus and LISA cohort

Author

Lambert, Katrina A., primary, Markevych, Iana, additional, Yang, Bo-Yi, additional, Bauer, Carl-Peter, additional, Berdel, Dietrich, additional, von Berg, Andrea, additional, Bergmann, Karl-Christian, additional, Lodge, Caroline, additional, Koletzko, Sibylle, additional, Prendergast, Luke A., additional, Schikowski, Tamara, additional, Schulz, Holger, additional, Werchan, Matthias, additional, Heinrich, Joachim, additional, Standl, Marie, additional, and Erbas, Bircan, additional

Published
2021
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109. Associations of Particulate Matter Sizes and Chemical Constituents with Blood Lipids: A Panel Study in Guangzhou, China

Author

He, Zhi-Zhou, primary, Guo, Peng-Yue, additional, Xu, Shu-Li, additional, Zhou, Yang, additional, Jalaludin, Bin, additional, Leskinen, Ari, additional, Knibbs, Luke D., additional, Heinrich, Joachim, additional, Morawska, Lidia, additional, Yim, Steve Hung-Lam, additional, Bui, Dinh, additional, Komppula, Mika, additional, Roponen, Marjut, additional, Hu, Liwen, additional, Chen, Gongbo, additional, Zeng, Xiao-Wen, additional, Yu, Yunjiang, additional, Yang, Bo-Yi, additional, and Dong, Guanghui, additional

Published
2021
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110. Long-term exposure to ambient air pollution and metabolic syndrome in children and adolescents: A national cross-sectional study in China

Author

Zhang, Jing-Shu, primary, Gui, Zhao-Huan, additional, Zou, Zhi-Yong, additional, Yang, Bo-Yi, additional, Ma, Jun, additional, Jing, Jin, additional, Wang, Hai-Jun, additional, Luo, Jia-You, additional, Zhang, Xin, additional, Luo, Chun-Yan, additional, Wang, Hong, additional, Zhao, Hai-Ping, additional, Pan, De-Hong, additional, Bao, Wen-Wen, additional, Guo, Yu-Ming, additional, Ma, Ying-Hua, additional, Dong, Guang-Hui, additional, and Chen, Ya-Jun, additional

Published
2021
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111. Current pet ownership modifies the adverse association between long‐term ambient air pollution exposure and childhood asthma

Author

Zeng, Xiao‐Wen, primary, Lodge, Caroline J., additional, Lowe, Adrian J., additional, Guo, Yuming, additional, Abramson, Michael J., additional, Bowatte, Gayan, additional, Hu, Li‐Wen, additional, Yang, Bo‐Yi, additional, Chen, Zan‐Xiong, additional, Dharmage, Shyamali C., additional, and Dong, Guang‐Hui, additional

Published
2021
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112. Is PM1 similar to PM2.5? A new insight into the association of PM1 and PM2.5 with children's lung function

Author

Yang, Mo, Guo, Yu Ming, Bloom, Michael S., Dharmagee, Shyamali C., Morawska, Lidia, Heinrich, Joachim, Jalaludin, Bin, Markevychd, Iana, Knibbs, Luke D., Lin, Shao, Hung Lan, Steve, Jalava, Pasi, Komppula, Mika, Roponen, Marjut, Hirvonen, Maija Riitta, Guan, Qi Hua, Liang, Zi Mian, Yu, Hong Yao, Hu, Li Wen, Yang, Bo Yi, Zeng, Xiao Wen, Dong, Guang Hui, Yang, Mo, Guo, Yu Ming, Bloom, Michael S., Dharmagee, Shyamali C., Morawska, Lidia, Heinrich, Joachim, Jalaludin, Bin, Markevychd, Iana, Knibbs, Luke D., Lin, Shao, Hung Lan, Steve, Jalava, Pasi, Komppula, Mika, Roponen, Marjut, Hirvonen, Maija Riitta, Guan, Qi Hua, Liang, Zi Mian, Yu, Hong Yao, Hu, Li Wen, Yang, Bo Yi, Zeng, Xiao Wen, and Dong, Guang Hui

Abstract

Experimental data suggests that PM1 is more toxic than PM2.5 although the epidemiologic evidence suggests that the health associations are similar. However, few objective exposure data are available to compare the associations of PM1 and PM2.5 with children lung function. Our objectives are a) to evaluate associations between long-term exposure to PM1, PM2.5 and children's lung function, and b) to compare the associations between PM1 and PM2.5. From 2012 to 2013, we enrolled 6,740 children (7–14 years), randomly recruited from primary and middle schools located in seven cities in northeast China. We measured lung function including forced vital capacity (FVC), forced expiratory volume in 1 s (FEV1), peak expiratory flow (PEF), and maximal mid-expiratory flow (MMEF) utilizing two portable electronic spirometers. We dichotomized continuous lung function measures according the expected values for gender and age. The spatial resolution at which PM1 and PM2.5 estimated were estimated using a machine learning method and the temporal average concentrations were averaged from 2009 to 2012. A multilevel regression model was used to estimate the associations of PM1, PM2.5 exposure and lung function measures, adjusted for confounding factors. Associations with lower lung function were consistently larger for PM1 than for PM2.5. Adjusted odds ratios (OR) per interquartile range greater PM1 ranged from 1.53 for MMEF (95% confidence interval [CI]: 1.20–1.96) to 2.14 for FEV1 (95% CI: 1.66–2.76) and ORs for PM2.5 ranged from 1.36 for MMEF (95%CI: 1.12–1.66) to 1.82 for FEV1 (95%CI: 1.49–2.22), respectively. PM1 and PM2.5 had significant associations with FVC and FEV1 in primary school children, and on PEF and MMEF in middle school children. Long-term PM1 and PM2.5

Published
2020

113. Association between residential greenness, cardiometabolic disorders, and cardiovascular disease among adults in China

Author

Yang, Bo Yi, Hu, Li Wen, Jalaludin, Bin, Knibbs, Luke D., Markevych, Iana, Heinrich, Joachim, Bloom, Michael S., Morawska, Lidia, Lin, Shao, Jalava, Pasi, Roponen, Marjut, Gao, Meng, Chen, Duo Hong, Zhou, Yang, Yu, Hong Yao, Liu, Ru Qing, Zeng, Xiao Wen, Zeeshan, Mohammed, Guo, Yuming, Yu, Yunjiang, Dong, Guang Hui, Yang, Bo Yi, Hu, Li Wen, Jalaludin, Bin, Knibbs, Luke D., Markevych, Iana, Heinrich, Joachim, Bloom, Michael S., Morawska, Lidia, Lin, Shao, Jalava, Pasi, Roponen, Marjut, Gao, Meng, Chen, Duo Hong, Zhou, Yang, Yu, Hong Yao, Liu, Ru Qing, Zeng, Xiao Wen, Zeeshan, Mohammed, Guo, Yuming, Yu, Yunjiang, and Dong, Guang Hui

Abstract

Importance: Living in areas with more vegetation (referred to as residential greenness) may be associated with cardiovascular disease (CVD), but little data are available from low- and middle-income countries. In addition, it remains unclear whether the presence of cardiometabolic disorders modifies or mediates the association between residential greenness and CVD. Objective: To evaluate the associations between residential greenness, cardiometabolic disorders, and CVD prevalence among adults in China. Design, Setting, and Participants: This analysis was performed as part of the 33 Communities Chinese Health Study, a large population-based cross-sectional study that was conducted in 33 communities (ranging from 0.25-0.64 km2) in 3 cities within the Liaoning province of northeastern China between April 1 and December 31, 2009. Participants included adults aged 18 to 74 years who had resided in the study area for 5 years or more. Greenness levels surrounding each participant's residential community were assessed using the normalized difference vegetation index and the soil-adjusted vegetation index from 2010. Lifetime CVD status (including myocardial infarction, heart failure, coronary heart disease, cerebral thrombosis, cerebral hemorrhage, cerebral embolism, and subarachnoid hemorrhage) was defined as a self-report of a physician diagnosis of CVD at the time of the survey. Cardiometabolic disorders, including hypertension, diabetes, dyslipidemia, and overweight or obese status, were measured and defined clinically. Generalized linear mixed models were used to evaluate the association between residential greenness levels and CVD prevalence. A 3-way decomposition method was used to explore whether the presence of cardiometabolic disorders mediated or modified the association between residential greenness and CVD. Data were analyzed from October 10 to May 30, 2020. Main Outcomes and Measures: Lifetime C

Published
2020

114. Association between community greenness and obesity in urban-dwelling Chinese adults

Author

Huang, Wen Zhong, Yang, Bo Yi, Yu, Hong Yao, Bloom, Michael S., Markevych, Iana, Heinrich, Joachim, Knibbs, Luke D., Leskinen, Ari, Dharmage, Shyamali C., Jalaludin, Bin, Morawska, Lidia, Jalava, Pasi, Guo, Yuming, Lin, Shao, Zhou, Yang, Liu, Ru Qing, Feng, Dan, Hu, Li Wen, Zeng, Xiao Wen, Hu, Qiang, Yu, Yunjing, Dong, Guang Hui, Huang, Wen Zhong, Yang, Bo Yi, Yu, Hong Yao, Bloom, Michael S., Markevych, Iana, Heinrich, Joachim, Knibbs, Luke D., Leskinen, Ari, Dharmage, Shyamali C., Jalaludin, Bin, Morawska, Lidia, Jalava, Pasi, Guo, Yuming, Lin, Shao, Zhou, Yang, Liu, Ru Qing, Feng, Dan, Hu, Li Wen, Zeng, Xiao Wen, Hu, Qiang, Yu, Yunjing, and Dong, Guang Hui

Abstract

Living in greener places may protect against obesity, but epidemiological evidence is inconsistent and mainly comes from developed nations. We aimed to investigate the association between greenness and obesity in Chinese adults and to assess air pollution and physical activity as mediators of the association. We recruited 24,845 adults from the 33 Communities Chinese Health Study in 2009. Central and peripheral obesity were defined by waist circumference (WC) and body mass index (BMI), respectively, based on international obesity standards. The Normalized Difference Vegetation Index (NDVI) was used to quantify community greenness. Two-level logistic and generalized linear mixed regression models were used to evaluate the association between NDVI and obesity, and a conditional mediation analysis was used also performed. In the adjusted models, an interquartile range increase in NDVI500-m was significantly associated with lower odds of peripheral 0.80 (95% confidence interval [CI]: 0.74–0.87) and central obesity 0.88 (95% CI: 0.83–0.93). Higher NDVI values were also significantly associated with lower BMI. Age, gender, and household income significantly modified associations between greenness and obesity, with stronger associations among women, older participants, and participants with lower household incomes. Air pollution mediated 2.1–20.8% of the greenness-obesity associations, but no mediating effects were observed for physical activity. In summary, higher community greenness level was associated with lower odds of central and peripheral obesity, especially among women, older participants, and those with lower household incomes. These associations were partially mediated by air pollutants. Future well-designed longitudinal studies are needed to confirm our findings.

Published
2020

115. Greenness may improve lung health in low–moderate but not high air pollution areas: Seven Northeastern Cities’ study

Author

Zhou, Yang, primary, Bui, Dinh S, additional, Perret, Jennifer L, additional, Lowe, Adrian J, additional, Lodge, Caroline J, additional, Markevych, Iana, additional, Heinrich, Joachim, additional, Bloom, Michael S, additional, Knibbs, Luke D, additional, Jalaludin, Bin, additional, Yang, Bo-Yi, additional, Yu, Hong-Yao, additional, Zeng, Xiao-Wen, additional, Yu, Yunjiang, additional, Dharmage, Shyamali C, additional, and Dong, Guang-Hui, additional

Published
2021
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116. Associations of ambient particulate matter with homocysteine metabolism markers and effect modification by B vitamins and MTHFR C677T gene polymorphism

Author

Yang, Bo-Yi, primary, Cao, Ke, additional, Luo, Ya-Na, additional, He, Zhi-Zhou, additional, Guo, Peng-Yue, additional, Ma, Hui-Min, additional, Yang, Mo, additional, Zhou, Yang, additional, Hu, Li-Wen, additional, Chen, Gong-Bo, additional, Zeng, Xiao-Wen, additional, Yu, Hong-Yao, additional, Yu, Yunjiang, additional, and Dong, Guang-Hui, additional

Published
2021
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117. A national cross-sectional study of exposure to outdoor nitrogen dioxide and aeroallergen sensitization in Australian children aged 7–11 years

Author

Tu, Yanhui, primary, Williams, Gail M., additional, Cortés de Waterman, Adriana M., additional, Toelle, Brett G., additional, Guo, Yuming, additional, Denison, Lyn, additional, Babu, Giridhara R., additional, Yang, Bo-Yi, additional, Dong, Guang-Hui, additional, Jalaludin, Bin, additional, Marks, Guy B., additional, and Knibbs, Luke D., additional

Published
2021
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118. Fine and Ultrafine Airborne Pm Influence Inflammation Response of Young Adults and Toxicological Responses in Vitro

Author

Yang, Mo, primary, Jalava, Pasi, additional, Hakkarainen, Henri, additional, Roponen, Marjut, additional, Leskinen, Ari, additional, Komppula, Mika, additional, Dong, Guo-Ping, additional, Lao, Xiang-Qian, additional, Wu, Qi-Zhen, additional, Xu, Shu-Li, additional, Lin, Li-Zi, additional, Liu, Ru-Qing, additional, Hu, Li-Wen, additional, Yang, Bo-Yi, additional, Zeng, Xiao-Wen, additional, and Dong, Guang-Hui, additional

Published
2021
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120. Greenness surrounding schools and adiposity in children and adolescents: Findings from a national population-based study in China

Author

Bao, Wen-Wen, primary, Yang, Bo-Yi, additional, Zou, Zhi-Yong, additional, Ma, Jun, additional, Jing, Jin, additional, Wang, Hai-Jun, additional, Luo, Jia-You, additional, Zhang, Xin, additional, Luo, Chun-Yan, additional, Wang, Hong, additional, Zhao, Hai-Ping, additional, Pan, De-Hong, additional, Gui, Zhao-Huan, additional, Zhang, Jing-Shu, additional, Guo, Yu-Ming, additional, Ma, Ying-Hua, additional, Dong, Guang-Hui, additional, and Chen, Ya-Jun, additional

Published
2021
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121. Is PM1 similar to PM2.5? A new insight into the association of PM1 and PM2.5 with children’s lung function

Author

Yang, Mo, primary, Guo, Yu-Ming, additional, Bloom, Michael S., additional, Dharmagee, Shyamali C., additional, Morawska, Lidia, additional, Heinrich, Joachim, additional, Jalaludin, Bin, additional, Markevychd, Iana, additional, Knibbsf, Luke D, additional, Lin, Shao, additional, Hung Lan, Steve, additional, Jalava, Pasi, additional, Komppula, Mika, additional, Roponen, Marjut, additional, Hirvonen, Maija-Riitta, additional, Guan, Qi-Hua, additional, Liang, Zi-Mian, additional, Yu, Hong-Yao, additional, Hu, Li-Wen, additional, Yang, Bo-Yi, additional, Zeng, Xiao-Wen, additional, and Dong, Guang-Hui, additional

Published
2020
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122. Serum levels of per- and polyfluoroalkyl substances alternatives and blood pressure by sex status: Isomers of C8 health project in China

Author

Mi, Xin, primary, Yang, Yun-Qing, additional, Zeeshan, Mohammed, additional, Wang, Zhi-Bin, additional, Zeng, Xiao-Yun, additional, Zhou, Yang, additional, Yang, Bo-Yi, additional, Hu, Li-Wen, additional, Yu, Hong-Yao, additional, Zeng, Xiao-Wen, additional, Liu, Ru-Qing, additional, and Dong, Guang-Hui, additional

Published
2020
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123. Modification of caesarean section on the associations between air pollution and childhood asthma in seven Chinese cities

Author

Yu, Hongyao, primary, Guo, Yuming, additional, Zeng, Xiaoyun, additional, Gao, Meng, additional, Yang, Bo-Yi, additional, Hu, Li-Wen, additional, Yu, Yunjiang, additional, Dong, Guang-Hui, additional, Zhou, Yang, additional, Qian, Zhengmin, additional, Sun, Jia, additional, McMillin, Stephen Edward, additional, Bloom, Michael S., additional, Heinrich, Joachim, additional, Markevych, Iana, additional, Morawska, Lidia, additional, Dharmage, Shyamali C., additional, Jalaludin, Bin, additional, Knibbs, Luke, additional, Lin, Shao, additional, Jalava, Pasi, additional, Roponen, Marjut, additional, Leskinen, Ari, additional, Komppula, Mika, additional, Hung-Lam Steve, Y.I.M., additional, Liu, Ru-Qing, additional, and Zeng, Xiao-Wen, additional

Published
2020
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125. Association Between Residential Greenness, Cardiometabolic Disorders, and Cardiovascular Disease Among Adults in China

Author

Yang, Bo-Yi, primary, Hu, Li-Wen, additional, Jalaludin, Bin, additional, Knibbs, Luke D., additional, Markevych, Iana, additional, Heinrich, Joachim, additional, Bloom, Michael S., additional, Morawska, Lidia, additional, Lin, Shao, additional, Jalava, Pasi, additional, Roponen, Marjut, additional, Gao, Meng, additional, Chen, Duo-Hong, additional, Zhou, Yang, additional, Yu, Hong-Yao, additional, Liu, Ru-Qing, additional, Zeng, Xiao-Wen, additional, Zeeshan, Mohammed, additional, Guo, Yuming, additional, Yu, Yunjiang, additional, and Dong, Guang-Hui, additional

Published
2020
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127. The role of influenza vaccination in mitigating the adverse impact of ambient air pollution on lung function in children: New insights from the Seven Northeastern Cities Study in China

Author

Liu, Kangkang, primary, Yang, Bo-Yi, additional, Guo, Yuming, additional, Bloom, Michael S., additional, Dharmage, Shyamali C., additional, Knibbs, Luke D., additional, Heinrich, Joachim, additional, Leskinen, Ari, additional, Lin, Shao, additional, Morawska, Lidia, additional, Jalaludin, Bin, additional, Markevych, Iana, additional, Jalava, Pasi, additional, Komppula, Mika, additional, Yu, Yunjiang, additional, Gao, Meng, additional, Zhou, Yang, additional, Yu, Hong-Yao, additional, Hu, Li-Wen, additional, Zeng, Xiao-Wen, additional, and Dong, Guang-Hui, additional

Published
2020
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131. Pet ownership in utero and in childhood decreases the effects of environmental tobacco smoke exposure on hypertension in children: A large population based cohort study

Author

Xu, Shu-Li, primary, Liu, Ai-Ping, additional, Wu, Qi-Zhen, additional, Marks, Tia, additional, He, Zhi-Zhou, additional, Qian, Zhengmin, additional, McMillin, Stephen Edward, additional, Sun, Jia, additional, Appleton, Allison A., additional, Bloom, Michael S., additional, Lin, Shao, additional, Yu, Hong-Yao, additional, Zhou, Yang, additional, Liu, Ru-Qing, additional, Feng, Dan, additional, Hu, Li-Wen, additional, Yang, Bo-Yi, additional, Zeng, Xiao-Wen, additional, Sun, Xiao, additional, and Dong, Guang-Hui, additional

Published
2020
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133. The time window of pet ownership exposure modifies the relationship of Environmental Tobacco Smoke with lung function: A large population-based cohort study

Author

Hu, Li-Wen, primary, Yu, Shu, additional, Marks, Tia, additional, Zhang, Yun-Ting, additional, Lodge, Caroline C., additional, Dharmage, Shyamali C., additional, Gurram, Namratha, additional, Bloom, Michael S., additional, Lin, Shao, additional, Zeeshan, Mohammed, additional, Yu, Hong-Yao, additional, Zhou, Yang, additional, Liu, Ru-Qing, additional, Yang, Bo-Yi, additional, Zeng, Xiao-Wen, additional, Hu, Qiang, additional, and Dong, Guang-Hui, additional

Published
2020
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134. Incidence of ocular conditions associated with perfluoroalkyl substances exposure: Isomers of C8 Health Project in China

Author

Zeeshan, Mohammed, primary, Yang, Yunqing, additional, Zhou, Yang, additional, Huang, Wenzhong, additional, Wang, Zhibin, additional, Zeng, Xiao-Yun, additional, Liu, Ru-Qing, additional, Yang, Bo-Yi, additional, Hu, Li-Wen, additional, Zeng, Xiao-Wen, additional, Sun, Xiao, additional, Yu, Yunjiang, additional, and Dong, Guang-Hui, additional

Published
2020
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136. Association between community greenness and obesity in urban-dwelling Chinese adults

Author

Huang, Wen-Zhong, primary, Yang, Bo-Yi, additional, Yu, Hong-Yao, additional, Bloom, Michael S., additional, Markevych, Iana, additional, Heinrich, Joachim, additional, Knibbs, Luke D., additional, Leskinen, Ari, additional, Dharmage, Shyamali C., additional, Jalaludin, Bin, additional, Morawska, Lidia, additional, Jalava, Pasi, additional, Guo, Yuming, additional, Lin, Shao, additional, Zhou, Yang, additional, Liu, Ru-Qing, additional, Feng, Dan, additional, Hu, Li-Wen, additional, Zeng, Xiao-Wen, additional, Hu, Qiang, additional, Yu, Yunjing, additional, and Dong, Guang-Hui, additional

Published
2020
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138. Association between residential greenness and metabolic syndrome in Chinese adults

Author

Yang, Bo-Yi, primary, Liu, Kang-Kang, additional, Markevych, Iana, additional, Knibbs, Luke D., additional, Bloom, Michael S., additional, Dharmage, Shaymali C., additional, Lin, Shao, additional, Morawska, Lidia, additional, Heinrich, Joachim, additional, Jalaludin, Bin, additional, Gao, Meng, additional, Guo, Yuming, additional, Zhou, Yang, additional, Huang, Wen-Zhong, additional, Yu, Hong-Yao, additional, Zeng, Xiao-Wen, additional, Hu, Li-Wen, additional, Hu, Qiang, additional, and Dong, Guang-Hui, additional

Published
2020
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139. Ambient Airborne Particulates of Diameter ≤1 μm, a Leading Contributor to the Association Between Ambient Airborne Particulates of Diameter ≤2.5 μm and Children’s Blood Pressure

Author

Wu, Qi-Zhen, primary, Li, Shanshan, additional, Yang, Bo-Yi, additional, Bloom, Michael, additional, Shi, Zhidong, additional, Knibbs, Luke, additional, Dharmage, Shyamali, additional, Leskinen, Ari, additional, Jalaludin, Bin, additional, Jalava, Pasi, additional, Roponen, Marjut, additional, Lin, Shao, additional, Chen, Gongbo, additional, Guo, Yuming, additional, Xu, Shu-Li, additional, Yu, Hong-Yao, additional, Zeeshan, Mohammed, additional, Hu, Li-Wen, additional, Yu, Yunjiang, additional, Zeng, Xiao-Wen, additional, and Dong, Guang-Hui, additional

Published
2020
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140. Greenness around schools associated with lower risk of hypertension among children: Findings from the Seven Northeastern Cities Study in China

Author

Xiao, Xiang, primary, Yang, Bo-Yi, additional, Hu, Li-Wen, additional, Markevych, Iana, additional, Bloom, Michael S., additional, Dharmage, Shyamali C., additional, Jalaludin, Bin, additional, Knibbs, Luke D., additional, Heinrich, Joachim, additional, Morawska, Lidia, additional, Lin, Shao, additional, Roponen, Marjut, additional, Guo, Yuming, additional, Lam Yim, Steve Hung, additional, Leskinen, Ari, additional, Komppula, Mika, additional, Jalava, Pasi, additional, Yu, Hong-Yao, additional, Zeeshan, Mohammed, additional, Zeng, Xiao-Wen, additional, and Dong, Guang-Hui, additional

Published
2020
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141. Benefits of influenza vaccination on the associations between ambient air pollution and allergic respiratory diseases in children and adolescents: New insights from the Seven Northeastern Cities study in China

Author

Liu, Kangkang, primary, Li, Shanshan, additional, Qian, Zhengmin (Min), additional, Dharmage, Shyamali C., additional, Bloom, Michael S., additional, Heinrich, Joachim, additional, Jalaludin, Bin, additional, Markevych, Iana, additional, Morawska, Lidia, additional, Knibbs, Luke D., additional, Hinyard, Leslie, additional, Xian, Hong, additional, Liu, Shan, additional, Lin, Shao, additional, Leskinen, Ari, additional, Komppula, Mika, additional, Jalava, Pasi, additional, Roponen, Marjut, additional, Hu, Li-Wen, additional, Zeng, Xiao-Wen, additional, Hu, Wenbiao, additional, Chen, Gongbo, additional, Yang, Bo-Yi, additional, Guo, Yuming, additional, and Dong, Guang-Hui, additional

Published
2020
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143. Association Between Greenness Surrounding Schools and Kindergartens and Attention-Deficit/Hyperactivity Disorder in Children in China

Author

Yang, Bo-Yi, primary, Zeng, Xiao-Wen, additional, Markevych, Iana, additional, Bloom, Michael S., additional, Heinrich, Joachim, additional, Knibbs, Luke D., additional, Dharmage, Shyamali C., additional, Lin, Shao, additional, Jalava, Pasi, additional, Guo, Yuming, additional, Jalaludin, Bin, additional, Morawska, Lidia, additional, Zhou, Yang, additional, Hu, Li-Wen, additional, Yu, Hong-Yao, additional, Yu, Yunjiang, additional, and Dong, Guang-Hui, additional

Published
2019
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145. Association between greenness surrounding schools and kindergartens and attention-deficit/hyperactivity disorder in children in China

Author

Yang, Bo Yi, Zeng, Xiao Wen, Markevych, Iana, Bloom, Michael S., Heinrich, Joachim, Knibbs, Luke D., Dharmage, Shyamali C., Lin, Shao, Jalava, Pasi, Guo, Yuming, Jalaludin, Bin, Morawska, Lidia, Zhou, Yang, Hu, Li Wen, Yu, Hong Yao, Yu, Yunjiang, Dong, Guang Hui, Yang, Bo Yi, Zeng, Xiao Wen, Markevych, Iana, Bloom, Michael S., Heinrich, Joachim, Knibbs, Luke D., Dharmage, Shyamali C., Lin, Shao, Jalava, Pasi, Guo, Yuming, Jalaludin, Bin, Morawska, Lidia, Zhou, Yang, Hu, Li Wen, Yu, Hong Yao, Yu, Yunjiang, and Dong, Guang Hui

Abstract

Importance: Few studies have investigated the association between greenness and childhood attention-deficit/hyperactivity disorder (ADHD). Objective: To evaluate the association between greenness surrounding schools or kindergartens and symptoms of ADHD in children. Design, Setting, and Participants: This population-based cross-sectional study was performed between April 2012 and January 2013 in 7 cities in northeastern China. This analysis included 59 754 children (aged 2-17 years) from 94 schools and kindergartens, who had resided in the study area for 2 years or longer. Data were analyzed from April 15, 2019, to October 10, 2019. Exposures: Greenness surrounding each child's school or kindergarten was estimated using 2 satellite image-derived vegetation indexes: the normalized difference vegetation index and the soil-adjusted vegetation index. Main Outcomes and Measures: Diagnostic and Statistical Manual of Mental Disorders (Fourth Edition) scales were used to measure ADHD symptoms (9 inattention symptoms and 9 hyperactivity-impulsivity symptoms). Parents or guardians rated the frequency of each of 18 ADHD symptoms during the preceding 6 months. Children with 6 or more symptoms of either inattention or hyperactivity-impulsivity were defined as having ADHD symptoms. Generalized linear mixed models were applied to estimate the association between greenness and ADHD symptoms. Results: The mean (SD) age of the 59 754 study participants was 10.3 (3.6) years, and 29 494 (49.4%) were girls. A total of 2566 participants (4.3%) had ADHD symptoms. Greenness levels differed substantially across schools and kindergartens. The normalized difference vegetation index within 500 m of a school or kindergarten ranged from -0.09 to 0.77. Greater greenness levels were associated with lower odds of ADHD symptoms. In covariate-adjusted models, a 0.1-unit increase in normalized diff

Published
2019

146. Greenness may improve lung health in low-moderate but not high air pollution areas: Seven Northeastern Cities' study.

Author

Yang Zhou, Dinh S. Bui, Perret, Jennifer L., Lowe, Adrian J., Lodge, Caroline J., Markevych, Iana, Heinrich, Joachim, Bloom, Michael S., Knibbs, Luke D., Jalaludin, Bin, Bo-Yi Yang, Hong-Yao Yu, Xiao-Wen Zeng, Yunjiang Yu, Dharmage, Shyamali C., Guang-Hui Dong, Zhou, Yang, Bui, Dinh S, Yang, Bo-Yi, and Yu, Hong-Yao

Subjects
ASTHMATICS, AIR pollution, WALKABILITY, BIOSPHERE, LUNGS, TOBACCO smoke pollution, THEMATIC mapper satellite, SULFUR compounds analysis, PARTICULATE matter, RESEARCH, CROSS-sectional method, RESEARCH methodology, MEDICAL cooperation, EVALUATION research, PLANTS, COMPARATIVE studies, SCHOOLS, PULMONARY function tests, ENVIRONMENTAL exposure
Abstract

Introduction: There is growing interest in the impact of greenness exposure on airway diseases, but the impact of greenness on lung function in children is limited. We aimed to investigate the associations between greenness surrounding schools and lung function in children and whether these associations are modified by air pollution exposure.Methods: Between 2012 and 2013, a cross-sectional survey and spirometry were performed among 6740 school children. Lung function patterns were determined as obstructive forced expiratory volume 1 s/forced vital capacity (FEV1/FVC <0.8) or restrictive (FEV1/FVC ≥0.8 but FVC <80% of predicted). School greenness was defined by Normalized difference vegetation index (NDVI) and soil-adjusted vegetation index. Nitrogen dioxide, sulphur dioxide and particular matter concentrations were assessed using a spatiotemporal model and national monitoring data. Two-level generalised linear models were used to investigate associations and interactions.Results: Overall, an IQR in NDVI within 500 m was associated with higher FEV1 (+57 mL 95% CI 44 to 70) and FVC (+58 mL 95% CI 43 to 73). NDVI was similarly associated with 25% reduced odds of spirometric restriction (OR: 0.75, 95% CI 0.65 to 0.86). However, among children exposed to the highest compared with the lowest quartile of particulate matter, increasing NDVI was paradoxically associated with lower -40 mL FVC (95% CI -47 to -33, p interaction <0.05).Discussion: Our findings suggest that, in this study population, greening urban areas may promote lung health in low-moderate pollution areas but not in high air pollution areas. If the findings are replicated in other moderate-to-high pollution settings, this highlights a need to have a flexible green policy. [ABSTRACT FROM AUTHOR]

Published
2021
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147. Residential greenness and blood lipids in urban-dwelling adults: The 33 Communities Chinese Health Study

Author

Yang, Bo-Yi, primary, Markevych, Iana, additional, Heinrich, Joachim, additional, Bloom, Michael S., additional, Qian, Zhengmin, additional, Geiger, Sarah Dee, additional, Vaughn, Michael, additional, Liu, Shan, additional, Guo, Yuming, additional, Dharmage, Shyamali C., additional, Jalaludin, Bin, additional, Knibbs, Luke D., additional, Chen, Da, additional, Jalava, Pasi, additional, Lin, Shao, additional, Hung-Lam Yim, Steve, additional, Liu, Kang-Kang, additional, Zeng, Xiao-Wen, additional, Hu, Li-Wen, additional, and Dong, Guang-Hui, additional

Published
2019
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148. Association of Breastfeeding and Air Pollution Exposure With Lung Function in Chinese Children

Author

Zhang, Chuan, primary, Guo, Yuming, additional, Xiao, Xiang, additional, Bloom, Michael S., additional, Qian, Zhengmin, additional, Rolling, Craig A., additional, Xian, Hong, additional, Lin, Shao, additional, Li, Shanshan, additional, Chen, Gongbo, additional, Jalava, Pasi, additional, Roponen, Marjut, additional, Hirvonen, Maija-Riitta, additional, Komppula, Mika, additional, Leskinen, Ari, additional, Yim, Steve Hung Lam, additional, Chen, Duo-Hong, additional, Ma, Huimin, additional, Zeng, Xiao-Wen, additional, Hu, Li-Wen, additional, Liu, Kang-Kang, additional, Yang, Bo-Yi, additional, and Dong, Guang-Hui, additional

Published
2019
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149. Community greenness, blood pressure, and hypertension in urban dwellers: The 33 Communities Chinese Health Study

Author

Yang, Bo-Yi, primary, Markevych, Iana, additional, Bloom, Michael S., additional, Heinrich, Joachim, additional, Guo, Yuming, additional, Morawska, Lidia, additional, Dharmage, Shyamali C., additional, Knibbs, Luke D., additional, Jalaludin, Bin, additional, Jalava, Pasi, additional, Zeng, Xiao-Wen, additional, Hu, Li-Wen, additional, Liu, Kang-Kang, additional, and Dong, Guang-Hui, additional

Published
2019
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150. Prenatal exposure to perfluoroalkyl substances is associated with lower hand, foot and mouth disease viruses antibody response in infancy: Findings from the Guangzhou Birth Cohort Study

Author

Zeng, Xiao-Wen, primary, Bloom, Michael S., additional, Dharmage, Shyamali C., additional, Lodge, Caroline J., additional, Chen, Da, additional, Li, Shanshan, additional, Guo, Yuming, additional, Roponen, Marjut, additional, Jalava, Pasi, additional, Hirvonen, Maija-Riitta, additional, Ma, Huimin, additional, Hao, Yuan-Tao, additional, Chen, Wen, additional, Yang, Mo, additional, Chu, Chu, additional, Li, Qing-Qing, additional, Hu, Li-Wen, additional, Liu, Kang-Kang, additional, Yang, Bo-Yi, additional, Liu, Shan, additional, Fu, Chuanxi, additional, and Dong, Guang-Hui, additional

Published
2019
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