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2,478 results on '"Xu, Zhigang"'

116. Secure and Trustable Electronic Medical Records Sharing using Blockchain

Author

Dubovitskaya, Alevtina, Xu, Zhigang, Ryu, Samuel, Schumacher, Michael, and Wang, Fusheng

Subjects
Computer Science - Computers and Society, Computer Science - Cryptography and Security
Abstract

Electronic medical records (EMRs) are critical, highly sensitive private information in healthcare, and need to be frequently shared among peers. Blockchain provides a shared, immutable and transparent history of all the transactions to build applications with trust, accountability and transparency. This provides a unique opportunity to develop a secure and trustable EMR data management and sharing system using blockchain. In this paper, we present our perspectives on blockchain based healthcare data management, in particular, for EMR data sharing between healthcare providers and for research studies. We propose a framework on managing and sharing EMR data for cancer patient care. In collaboration with Stony Brook University Hospital, we implemented our framework in a prototype that ensures privacy, security, availability, and fine-grained access control over EMR data. The proposed work can significantly reduce the turnaround time for EMR sharing, improve decision making for medical care, and reduce the overall cost, Comment: AMIA 2017 Annual Symposium Proceedings

Published
2017

117. Calibration Methods for Large-Scale and High-Precision Globalization of Local Point Cloud Data Based on iGPS.

Author

Han, Rui, Dunker, Thomas, Trostmann, Erik, and Xu, Zhigang

Abstract

The point cloud is one of the measurement results of local measurement and is widely used because of its high measurement accuracy, high data density, and low environmental impact. However, since point cloud data from a single measurement are generally small in spatial extent, it is necessary to accurately globalize the local point cloud to measure large components. In this paper, the method of using an iGPS (indoor Global Positioning System) as an external measurement device to realize high-accuracy globalization of local point cloud data is proposed. Two calibration models are also discussed for different application scenarios. Verification experiments prove that the average calibration errors of these two calibration models are 0.12 mm and 0.17 mm, respectively. The proposed method can maintain calibration precision in a large spatial range (about 10 m × 10 m × 5 m), which is of high value for engineering applications. [ABSTRACT FROM AUTHOR]

Published
2024
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118. Gold Nanodots‐Anchored Cobalt Ferrite Nanoflowers as Versatile Tumor Microenvironment Modulators for Reinforced Redox Dyshomeostasis.

Author

Zeng, Guicheng, Mao, Jinning, Xing, Haiyan, Xu, Zhigang, Cao, Zhong, Kang, Yuejun, Liu, Guodong, and Xue, Peng

Subjects
CELL death inhibition, GLUCOSE oxidase, OXIDATION of glucose, TUMOR microenvironment, TREATMENT effectiveness
Abstract

Given that tumor microenvironment (TME) exerts adverse impact on the therapeutic response and clinical outcome, robust TME modulators may significantly improve the curative effect and increase survival benefits of cancer patients. Here, Au nanodots‐anchored CoFe2O4 nanoflowers with PEGylation (CFAP) are developed to respond to TME cues, aiming to exacerbate redox dyshomeostasis for efficacious antineoplastic therapy under ultrasound (US) irradiation. After uptake by tumor cells, CFAP with glucose oxidase (GOx)‐like activity can facilitate glucose depletion and promote the production of H2O2. Multivalent elements of Co(II)/Co(III) and Fe(II)/Fe(III) in CFAP display strong Fenton‐like activity for·OH production from H2O2. On the other hand, energy band structure CFAP is superior for US‐actuated 1O2 generation, relying on the enhanced separation and retarded recombination of e−/h+ pairs. In addition, catalase‐mimic CFAP can react with cytosolic H2O2 to generate molecular oxygen, which may increase the product yields from O2‐consuming reactions, such as glucose oxidation and sonosensitization processes. Besides the massive production of reactive oxygen species, CFAP is also capable of exhausting glutathione to devastate intracellular redox balance. Severe immunogenic cell death and effective inhibition of solid tumor by CFAP demonstrates the clinical potency of such heterogeneous structure and may inspire more relevant designs for disease therapy. [ABSTRACT FROM AUTHOR]

Published
2024
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122. A DNN Inference Acceleration Algorithm in Heterogeneous Edge Computing: Joint Task Allocation and Model Partition

Author

Shi, Lei, Xu, Zhigang, Shi, Yi, Fan, Yuqi, Ding, Xu, Sun, Yabo, Akan, Ozgur, Editorial Board Member, Bellavista, Paolo, Editorial Board Member, Cao, Jiannong, Editorial Board Member, Coulson, Geoffrey, Editorial Board Member, Dressler, Falko, Editorial Board Member, Ferrari, Domenico, Editorial Board Member, Gerla, Mario, Editorial Board Member, Kobayashi, Hisashi, Editorial Board Member, Palazzo, Sergio, Editorial Board Member, Sahni, Sartaj, Editorial Board Member, Shen, Xuemin (Sherman), Editorial Board Member, Stan, Mircea, Editorial Board Member, Jia, Xiaohua, Editorial Board Member, Zomaya, Albert Y., Editorial Board Member, Gao, Honghao, editor, Wang, Xinheng, editor, Iqbal, Muddesar, editor, Yin, Yuyu, editor, Yin, Jianwei, editor, and Gu, Ning, editor

Published
2021
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124. Online Task Scheduling for DNN-Based Applications over Cloud, Edge and End Devices

Author

Zhong, Lixiang, Shi, Jiugen, Shi, Lei, Xu, Juan, Fan, Yuqi, Xu, Zhigang, Goos, Gerhard, Founding Editor, Hartmanis, Juris, Founding Editor, Bertino, Elisa, Editorial Board Member, Gao, Wen, Editorial Board Member, Steffen, Bernhard, Editorial Board Member, Woeginger, Gerhard, Editorial Board Member, Yung, Moti, Editorial Board Member, Liu, Zhe, editor, Wu, Fan, editor, and Das, Sajal K., editor

Published
2021
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139. An Experimental Method for CAV Dedicated Lane Setting Strategy

Author

Zhu, Hongge, Zhu, Xiaodong, Xu, Zhigang, Tian, Bin, Zhang, Yuqin, Filipe, Joaquim, Editorial Board Member, Ghosh, Ashish, Editorial Board Member, Prates, Raquel Oliveira, Editorial Board Member, Zhou, Lizhu, Editorial Board Member, Wang, Jiangtao, editor, Chen, Longbiao, editor, Tang, Lei, editor, and Liang, Yunji, editor

Published
2020
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