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1,118 results on '"Wu, Chin-Lee"'

101. Supplemental Table 1 from Aberrant FGFR Tyrosine Kinase Signaling Enhances the Warburg Effect by Reprogramming LDH Isoform Expression and Activity in Prostate Cancer

Author

Liu, Junchen, primary, Chen, Guo, primary, Liu, Zezhen, primary, Liu, Shaoyou, primary, Cai, Zhiduan, primary, You, Pan, primary, Ke, Yuepeng, primary, Lai, Li, primary, Huang, Yun, primary, Gao, Hongchang, primary, Zhao, Liangcai, primary, Pelicano, Helene, primary, Huang, Peng, primary, McKeehan, Wallace L., primary, Wu, Chin-Lee, primary, Wang, Cong, primary, Zhong, Weide, primary, and Wang, Fen, primary

Published
2023
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102. Data from Aberrant FGFR Tyrosine Kinase Signaling Enhances the Warburg Effect by Reprogramming LDH Isoform Expression and Activity in Prostate Cancer

Author

Liu, Junchen, primary, Chen, Guo, primary, Liu, Zezhen, primary, Liu, Shaoyou, primary, Cai, Zhiduan, primary, You, Pan, primary, Ke, Yuepeng, primary, Lai, Li, primary, Huang, Yun, primary, Gao, Hongchang, primary, Zhao, Liangcai, primary, Pelicano, Helene, primary, Huang, Peng, primary, McKeehan, Wallace L., primary, Wu, Chin-Lee, primary, Wang, Cong, primary, Zhong, Weide, primary, and Wang, Fen, primary

Published
2023
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103. Supplementary Methods from miR-195 Inhibits Tumor Progression by Targeting RPS6KB1 in Human Prostate Cancer

Author

Cai, Chao, primary, Chen, Qing-Biao, primary, Han, Zhao-Dong, primary, Zhang, Yan-Qiong, primary, He, Hui-Chan, primary, Chen, Jia-Hong, primary, Chen, Yan-Ru, primary, Yang, Sheng-Bang, primary, Wu, Yong-Ding, primary, Zeng, Yan-Ru, primary, Qin, Guo-Qiang, primary, Liang, Yu-Xiang, primary, Dai, Qi-Shan, primary, Jiang, Fu-Neng, primary, Wu, Shu-lin, primary, Zeng, Guo-Hua, primary, Zhong, Wei-De, primary, and Wu, Chin-Lee, primary

Published
2023
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104. Supplementary Figure 1 legend from Branched Chain RNA In Situ Hybridization for Androgen Receptor Splice Variant AR-V7 as a Prognostic Biomarker for Metastatic Castration-Sensitive Prostate Cancer

Author

Saylor, Philip J., primary, Lee, Richard J., primary, Arora, Kshitij S., primary, Deshpande, Vikram, primary, Hu, Rong, primary, Olivier, Kara, primary, Meneely, Erika, primary, Rivera, Miguel N., primary, Ting, David T., primary, Wu, Chin-Lee, primary, and Miyamoto, David T., primary

Published
2023
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105. Supplementary Data from Molecular Characterization of Neuroendocrine-like Bladder Cancer

Author

Batista da Costa, José, primary, Gibb, Ewan A., primary, Bivalacqua, Trinity J., primary, Liu, Yang, primary, Oo, Htoo Zarni, primary, Miyamoto, David T., primary, Alshalalfa, Mohammed, primary, Davicioni, Elai, primary, Wright, Jonathan, primary, Dall’Era, Marc A., primary, Douglas, James, primary, Boormans, Joost L., primary, Van der Heijden, Michiel S., primary, Wu, Chin-Lee, primary, van Rhijn, Bas W.G., primary, Gupta, Shilpa, primary, Grivas, Petros, primary, Mouw, Kent W., primary, Murugan, Paari, primary, Fazli, Ladan, primary, Ra, Seong, primary, Konety, Badrinath R., primary, Seiler, Roland, primary, Daneshmand, Siamak, primary, Mian, Omar Y., primary, Efstathiou, Jason A., primary, Lotan, Yair, primary, and Black, Peter C., primary

Published
2023
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106. Figure S5 from GPD1 Enhances the Anticancer Effects of Metformin by Synergistically Increasing Total Cellular Glycerol-3-Phosphate

Author

Xie, Jianjiang, primary, Ye, Jianheng, primary, Cai, Zhiduan, primary, Luo, Yong, primary, Zhu, Xuejin, primary, Deng, Yulin, primary, Feng, Yuanfa, primary, Liang, Yingke, primary, Liu, Ren, primary, Han, Zhaodong, primary, Liang, Yuxiang, primary, Zheng, Yu, primary, Mo, Rujun, primary, Zhuo, Yangjia, primary, Wu, Yongding, primary, Jiang, Funeng, primary, Zhu, Jianguo, primary, Wu, Chin-Lee, primary, and Zhong, Weide, primary

Published
2023
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108. Table S1 from GPD1 Enhances the Anticancer Effects of Metformin by Synergistically Increasing Total Cellular Glycerol-3-Phosphate

Author

Xie, Jianjiang, primary, Ye, Jianheng, primary, Cai, Zhiduan, primary, Luo, Yong, primary, Zhu, Xuejin, primary, Deng, Yulin, primary, Feng, Yuanfa, primary, Liang, Yingke, primary, Liu, Ren, primary, Han, Zhaodong, primary, Liang, Yuxiang, primary, Zheng, Yu, primary, Mo, Rujun, primary, Zhuo, Yangjia, primary, Wu, Yongding, primary, Jiang, Funeng, primary, Zhu, Jianguo, primary, Wu, Chin-Lee, primary, and Zhong, Weide, primary

Published
2023
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109. Supplementary Tab S1-S9 from miR-195 Inhibits Tumor Progression by Targeting RPS6KB1 in Human Prostate Cancer

Author

Cai, Chao, primary, Chen, Qing-Biao, primary, Han, Zhao-Dong, primary, Zhang, Yan-Qiong, primary, He, Hui-Chan, primary, Chen, Jia-Hong, primary, Chen, Yan-Ru, primary, Yang, Sheng-Bang, primary, Wu, Yong-Ding, primary, Zeng, Yan-Ru, primary, Qin, Guo-Qiang, primary, Liang, Yu-Xiang, primary, Dai, Qi-Shan, primary, Jiang, Fu-Neng, primary, Wu, Shu-lin, primary, Zeng, Guo-Hua, primary, Zhong, Wei-De, primary, and Wu, Chin-Lee, primary

Published
2023
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110. Supplementary Figure 1 from Branched Chain RNA In Situ Hybridization for Androgen Receptor Splice Variant AR-V7 as a Prognostic Biomarker for Metastatic Castration-Sensitive Prostate Cancer

Author

Saylor, Philip J., primary, Lee, Richard J., primary, Arora, Kshitij S., primary, Deshpande, Vikram, primary, Hu, Rong, primary, Olivier, Kara, primary, Meneely, Erika, primary, Rivera, Miguel N., primary, Ting, David T., primary, Wu, Chin-Lee, primary, and Miyamoto, David T., primary

Published
2023
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111. Data from GPD1 Enhances the Anticancer Effects of Metformin by Synergistically Increasing Total Cellular Glycerol-3-Phosphate

Author

Xie, Jianjiang, primary, Ye, Jianheng, primary, Cai, Zhiduan, primary, Luo, Yong, primary, Zhu, Xuejin, primary, Deng, Yulin, primary, Feng, Yuanfa, primary, Liang, Yingke, primary, Liu, Ren, primary, Han, Zhaodong, primary, Liang, Yuxiang, primary, Zheng, Yu, primary, Mo, Rujun, primary, Zhuo, Yangjia, primary, Wu, Yongding, primary, Jiang, Funeng, primary, Zhu, Jianguo, primary, Wu, Chin-Lee, primary, and Zhong, Weide, primary

Published
2023
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112. Fig s1-s8 from Aberrant FGFR Tyrosine Kinase Signaling Enhances the Warburg Effect by Reprogramming LDH Isoform Expression and Activity in Prostate Cancer

Author

Liu, Junchen, primary, Chen, Guo, primary, Liu, Zezhen, primary, Liu, Shaoyou, primary, Cai, Zhiduan, primary, You, Pan, primary, Ke, Yuepeng, primary, Lai, Li, primary, Huang, Yun, primary, Gao, Hongchang, primary, Zhao, Liangcai, primary, Pelicano, Helene, primary, Huang, Peng, primary, McKeehan, Wallace L., primary, Wu, Chin-Lee, primary, Wang, Cong, primary, Zhong, Weide, primary, and Wang, Fen, primary

Published
2023
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113. Supplementary Figures from Molecular Characterization of Neuroendocrine-like Bladder Cancer

Author

Batista da Costa, José, primary, Gibb, Ewan A., primary, Bivalacqua, Trinity J., primary, Liu, Yang, primary, Oo, Htoo Zarni, primary, Miyamoto, David T., primary, Alshalalfa, Mohammed, primary, Davicioni, Elai, primary, Wright, Jonathan, primary, Dall’Era, Marc A., primary, Douglas, James, primary, Boormans, Joost L., primary, Van der Heijden, Michiel S., primary, Wu, Chin-Lee, primary, van Rhijn, Bas W.G., primary, Gupta, Shilpa, primary, Grivas, Petros, primary, Mouw, Kent W., primary, Murugan, Paari, primary, Fazli, Ladan, primary, Ra, Seong, primary, Konety, Badrinath R., primary, Seiler, Roland, primary, Daneshmand, Siamak, primary, Mian, Omar Y., primary, Efstathiou, Jason A., primary, Lotan, Yair, primary, and Black, Peter C., primary

Published
2023
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114. Supplementary Fig. S1-S9 from miR-195 Inhibits Tumor Progression by Targeting RPS6KB1 in Human Prostate Cancer

Author

Cai, Chao, primary, Chen, Qing-Biao, primary, Han, Zhao-Dong, primary, Zhang, Yan-Qiong, primary, He, Hui-Chan, primary, Chen, Jia-Hong, primary, Chen, Yan-Ru, primary, Yang, Sheng-Bang, primary, Wu, Yong-Ding, primary, Zeng, Yan-Ru, primary, Qin, Guo-Qiang, primary, Liang, Yu-Xiang, primary, Dai, Qi-Shan, primary, Jiang, Fu-Neng, primary, Wu, Shu-lin, primary, Zeng, Guo-Hua, primary, Zhong, Wei-De, primary, and Wu, Chin-Lee, primary

Published
2023
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116. Supplementary information from GPD1 Enhances the Anticancer Effects of Metformin by Synergistically Increasing Total Cellular Glycerol-3-Phosphate

Author

Xie, Jianjiang, primary, Ye, Jianheng, primary, Cai, Zhiduan, primary, Luo, Yong, primary, Zhu, Xuejin, primary, Deng, Yulin, primary, Feng, Yuanfa, primary, Liang, Yingke, primary, Liu, Ren, primary, Han, Zhaodong, primary, Liang, Yuxiang, primary, Zheng, Yu, primary, Mo, Rujun, primary, Zhuo, Yangjia, primary, Wu, Yongding, primary, Jiang, Funeng, primary, Zhu, Jianguo, primary, Wu, Chin-Lee, primary, and Zhong, Weide, primary

Published
2023
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117. Supplementary Figure Legends 1-6 from Identification of the ENT1 Antagonists Dipyridamole and Dilazep as Amplifiers of Oncolytic Herpes Simplex Virus-1 Replication

Author

Passer, Brent J., primary, Cheema, Tooba, primary, Zhou, Bingsen, primary, Wakimoto, Hiroaki, primary, Zaupa, Cecile, primary, Razmjoo, Mani, primary, Sarte, Jason, primary, Wu, Shulin, primary, Wu, Chin-lee, primary, Noah, James W., primary, Li, Qianjun, primary, Buolamwini, John K., primary, Yen, Yun, primary, Rabkin, Samuel D., primary, and Martuza, Robert L., primary

Published
2023
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118. Supplementary Figures 1-6 from Identification of the ENT1 Antagonists Dipyridamole and Dilazep as Amplifiers of Oncolytic Herpes Simplex Virus-1 Replication

Author

Passer, Brent J., primary, Cheema, Tooba, primary, Zhou, Bingsen, primary, Wakimoto, Hiroaki, primary, Zaupa, Cecile, primary, Razmjoo, Mani, primary, Sarte, Jason, primary, Wu, Shulin, primary, Wu, Chin-lee, primary, Noah, James W., primary, Li, Qianjun, primary, Buolamwini, John K., primary, Yen, Yun, primary, Rabkin, Samuel D., primary, and Martuza, Robert L., primary

Published
2023
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119. Supplementary Materials and Methods from Identification of the ENT1 Antagonists Dipyridamole and Dilazep as Amplifiers of Oncolytic Herpes Simplex Virus-1 Replication

Author

Passer, Brent J., primary, Cheema, Tooba, primary, Zhou, Bingsen, primary, Wakimoto, Hiroaki, primary, Zaupa, Cecile, primary, Razmjoo, Mani, primary, Sarte, Jason, primary, Wu, Shulin, primary, Wu, Chin-lee, primary, Noah, James W., primary, Li, Qianjun, primary, Buolamwini, John K., primary, Yen, Yun, primary, Rabkin, Samuel D., primary, and Martuza, Robert L., primary

Published
2023
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121. Data from Identification of the ENT1 Antagonists Dipyridamole and Dilazep as Amplifiers of Oncolytic Herpes Simplex Virus-1 Replication

Author

Passer, Brent J., primary, Cheema, Tooba, primary, Zhou, Bingsen, primary, Wakimoto, Hiroaki, primary, Zaupa, Cecile, primary, Razmjoo, Mani, primary, Sarte, Jason, primary, Wu, Shulin, primary, Wu, Chin-lee, primary, Noah, James W., primary, Li, Qianjun, primary, Buolamwini, John K., primary, Yen, Yun, primary, Rabkin, Samuel D., primary, and Martuza, Robert L., primary

Published
2023
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127. TSC2 inactivation, low mutation burden and high macrophage infiltration characterise hepatic angiomyolipomas.

Author

Giannikou, Krinio, Klonowska, Katarzyna, Tsuji, Junko, Wu, Shulin, Zhu, Zachary, Probst, Clemens K, Kao, Katrina Z, Wu, Chin‐Lee, Rodig, Scott, Marino‐Enriquez, Adrian, Zen, Yoh, Schaefer, Inga‐Marie, and Kwiatkowski, David J

Subjects
ANGIOMYOLIPOMA, TUMOR microenvironment, SOMATIC mutation, GENETIC mutation, MACROPHAGES, VIRUS inactivation
Abstract

Aims: Although TSC1 or TSC2 inactivating mutations that lead to mTORC1 hyperactivation have been reported in hepatic angiomyolipomas (hAML), the role of other somatic genetic events that may contribute to hAML development is unknown. There are also limited data regarding the tumour microenvironment (TME) of hAML. The aim of the present study was to identify other somatic events in genomic level and changes in TME that contribute to tumorigenesis in hAML. Methods and results: In this study, we performed exome sequencing in nine sporadic hAML tumours and deep‐coverage targeted sequencing for TSC2 in three additional hAML. Immunohistochemistry and multiplex immunofluorescence were carried out for 15 proteins to characterise the tumour microenvironment and assess immune cell infiltration. Inactivating somatic variants in TSC2 were identified in 10 of 12 (83%) cases, with a median allele frequency of 13.6%. Five to 18 somatic variants (median number: nine, median allele frequency 21%) not in TSC1 or TSC2 were also identified, mostly of uncertain clinical significance. Copy number changes were rare, but detection was impaired by low tumour purity. Immunohistochemistry demonstrated numerous CD68+ macrophages of distinct appearance from Küpffer cells. Multiplex immunofluorescence revealed low numbers of exhausted PD‐1+/PD‐L1+, FOXP3+ and CD8+ T cells. Conclusion: hAML tumours have consistent inactivating mutations in TSC2 and have a low somatic mutation rate, similar to other TSC‐associated tumours. Careful histological review, standard IHC and multiplex immunofluorescence demonstrated marked infiltration by non‐neoplastic inflammatory cells, mostly macrophages. [ABSTRACT FROM AUTHOR]

Published
2023
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131. The Clinical Significance of the Positive Surgical Margin and Dominant Tumor Laterality Following Radical Prostatectomy: A Retrospective Study

Author

Wu, Shulin, primary, Lin, Sharron X., additional, Wirth, Gregory J., additional, Subtelny, Alexander O., additional, Lu, Min, additional, Lu, Jian, additional, Wang, Zongwei, additional, Olumi, Aria F., additional, Dahl, Douglas M., additional, Blute, Michael L., additional, and Wu, Chin-Lee, additional

Published
2022
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139. Viral proteins and virus-like particles of the LTR5_Hs endogenous retrovirus in human primordial germ cell-like cells

Author

Kobayashi, Mutsumi, primary, Kobayashi, Misato, additional, Kreuzer, Johannes, additional, Zaniewski, Eric, additional, Kim, Jae Jung, additional, Shioda, Keiko, additional, Hagihara, Hikari, additional, Odajima, Junko, additional, Nakashoji, Ayako, additional, Zheng, Yi, additional, Fu, Jianping, additional, Ericsson, Maria, additional, Kawamura, Kazuhiro, additional, Stott, Shannon L., additional, Irimia, Daniel, additional, Haas, Wilhelm, additional, Wu, Chin-Lee, additional, Tokuyama, Maria, additional, and Shioda, Toshi, additional

Published
2022
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140. Implementation and Clinical Adoption of Precision Oncology Workflows Across a Healthcare Network

Author

Dias-Santagata, Dora, primary, Heist, Rebecca S, additional, Bard, Adam Z, additional, da Silva, Annacarolina F L, additional, Dagogo-Jack, Ibiayi, additional, Nardi, Valentina, additional, Ritterhouse, Lauren L, additional, Spring, Laura M, additional, Jessop, Nicholas, additional, Farahani, Alexander A, additional, Mino-Kenudson, Mari, additional, Allen, Jill, additional, Goyal, Lipika, additional, Parikh, Aparna, additional, Misdraji, Joseph, additional, Shankar, Ganesh, additional, Jordan, Justin T, additional, Martinez-Lage, Maria, additional, Frosch, Matthew, additional, Graubert, Timothy, additional, Fathi, Amir T, additional, Hobbs, Gabriela S, additional, Hasserjian, Robert P, additional, Raje, Noopur, additional, Abramson, Jeremy, additional, Schwartz, Joel H, additional, Sullivan, Ryan J, additional, Miller, David, additional, Hoang, Mai P, additional, Isakoff, Steven, additional, Ly, Amy, additional, Bouberhan, Sara, additional, Watkins, Jaclyn, additional, Oliva, Esther, additional, Wirth, Lori, additional, Sadow, Peter M, additional, Faquin, William, additional, Cote, Gregory M, additional, Hung, Yin P, additional, Gao, Xin, additional, Wu, Chin-Lee, additional, Garg, Salil, additional, Rivera, Miguel, additional, Le, Long P, additional, John Iafrate, A, additional, Juric, Dejan, additional, Hochberg, Ephraim P, additional, Clark, Jeffrey, additional, Bardia, Aditya, additional, and Lennerz, Jochen K, additional

Published
2022
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141. A new transcriptional metastatic signature predicts survival in clear cell renal cell carcinoma

Author

Alchahin, Adele M., primary, Mei, Shenglin, additional, Tsea, Ioanna, additional, Hirz, Taghreed, additional, Kfoury, Youmna, additional, Dahl, Douglas, additional, Wu, Chin-Lee, additional, Subtelny, Alexander O., additional, Wu, Shulin, additional, Scadden, David T., additional, Shin, John H., additional, Saylor, Philip J., additional, Sykes, David B., additional, Kharchenko, Peter V., additional, and Baryawno, Ninib, additional

Published
2022
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147. Abstract 982: A new transcriptional metastatic signature predicts survival in clear cell renal cell carcinoma

Author

Alchahin, Adele Mirna, primary, Mei, Shenglin, additional, Tsea, Ioanna, additional, Hirz, Taghreed, additional, Kfoury, Youmna, additional, Dahl, Douglas, additional, Wu, Chin-Lee, additional, Subtelny, Alexander O., additional, WU, Shulin, additional, Scadden, David T., additional, Shin, John H., additional, Saylor, Philip J., additional, Sykes, David B., additional, Kharchenko, Peter V., additional, and Baryawno, Ninib, additional

Published
2022
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148. Abstract 2510: An atlas of single-cell and spatial transcriptomics reveals alterations that correlate with human prostate cancer progression

Author

Hirz, Taghreed, primary, Mei, Shenglin, additional, Sarkar, Hirak, additional, Kfoury, Youmna, additional, Wu, Shulin, additional, Wu, Chin-Lee, additional, Chen, Fei, additional, Macosko, Evan Z., additional, Dahl, Douglas M., additional, Baryawno, Ninib, additional, Scadden, David T., additional, Saylor, Philip J., additional, Kharchenko, Peter V., additional, and Sykes, David B., additional

Published
2022
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149. Abstract 2322: Multiplatform metabolomics studies of human cancers with NMR and mass spectrometry imaging

Author

Cheng, Leo L., primary, Zhong, Anya B., additional, Muti, Isabella H., additional, Eyles, Stephen J., additional, Vachet, Richard W., additional, Stopka, Sylwia A., additional, Sikora, Kristen N., additional, Bobst, Cedric E., additional, Agar, Jeffrey N., additional, Mino-Kenudson, Mari A., additional, Wu, Chin-Lee, additional, Christiani, David C., additional, Kaltashov, Igor A., additional, and Agar, Nathalie Y., additional

Published
2022
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150. Abstract 2222: Detecting clinically significant prostate cancers: Tissue metabolomics refines multiparametric MRI-ultrasound fusion prostate biopsy

Author

Cheng, Leo L., primary, Feldman, Adam S., additional, Vandergrift, Lindsey A., additional, Muti, Isabella H., additional, Rumpf, Florian, additional, Gusev, Andrew, additional, Berker, Yannick, additional, Cardoso, Marcella R., additional, Fuss, Taylor L., additional, Negroponte, Emily D., additional, Wu, Shulin, additional, Ehret, Felix, additional, Dietz, Christopher A., additional, Dinges, Sarah S., additional, Chulroek, Thitinan, additional, Nicaise, Edouard, additional, Habbel, Piet, additional, Ayree, Martin, additional, Nowak, Johannes, additional, Dahl, Douglas M., additional, Wu, Chin-Lee, additional, and Harisinghani, Mukesh, additional

Published
2022
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