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529 results on '"Wang, Yongfang"'

121. Responsive features of SiPRR37 to photoperiod and temperature, abiotic stress and identification of its favourable allelic variations in foxtail millet ( Setaria italica L.)

Author

Xiao-Mei Zhang, Jian-Feng Li, Bo Zhang, Zhi-Ping Dong, Zhen-Shan Wang, Wang Yongfang, Jianzhang Quan, Yuan Zhao, Xiao-Ping Jia, and Lu-Man Sang

Subjects
photoperiodism, Setaria, biology, Abiotic stress, Botany, Foxtail, Identification (biology), Plant Science, Allele, biology.organism_classification, Agronomy and Crop Science, Biotechnology
Published
2020

123. Additional file 1 of Construction of a predictive model for immunotherapy efficacy in lung squamous cell carcinoma based on the degree of tumor-infiltrating immune cells and molecular typing

Author

Yang, Lingge, Wei, Shuli, Zhang, Jingnan, Hu, Qiongjie, Hu, Wansong, Cao, Mengqing, Zhang, Long, Wang, Yongfang, Wang, Pingli, and Wang, Kai

Abstract

Additional file 1: Figure S1. The NMF rank survey at a rank of 2 to 10. Figure S2. All heatmaps of the training set with the number of clusters ranged from 2 to 10. Figure S3. The ten patients’ best response evaluation in our independent LUSC cohort according to response evaluation criteria in solid tumours (RECIST, v1.1). Figure S4. Correlation analysis between IPTS and (A) stromal score, (B) immune score, (C) ESTIMATE score, (D) CTLA4 TPM value, (E) PDCD1 (PD-1) TPM value, (F) CD274 (PD-L1) TPM value, and (G) PDCD1LG2 (PD-L2) TPM value.

Published
2022
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134. The predictive and prognostic effects of PD-L1 expression on TKI treatment and survival of EGFR-mutant NSCLC

Author

Lan, Bo, Wang, Yongfang, Wu, Jingni, Wang, Kai, and Wang, Pingli

Subjects
programmed death-ligand 1, Lung Neoplasms, Survival Analysis, B7-H1 Antigen, Progression-Free Survival, respiratory tract diseases, ErbB Receptors, Observational Studies as Topic, Meta-Analysis of Observational Studies in Epidemiology, tyrosine kinase inhibitor, Carcinoma, Non-Small-Cell Lung, Biomarkers, Tumor, Humans, epidermal growth factor receptor, Protein Kinase Inhibitors, Research Article, nonsmall cell lung cancer
Abstract

Whether programmed death-ligand 1 (PD-L1) expression could predict the outcome of tyrosine kinase inhibitor (TKI) treatment and prognosis of epidermal growth factor receptor (EGFR)-mutant nonsmall cell lung cancer (NSCLC) is remaining controversial. Potential studies were search from PubMed, Embase, and Web of Science databases. Pooled odds ratio of objective response rate was used to describe the relationship between PD-L1 expression and primary resistance to EGFR-TKIs. Pooled hazard ratios (HRs) of progression-free survival (PFS) and overall survival (OS) were included to assess the effects of PD-L1 status on the outcome of EGFR-TKI treatment and survival of EGFR-mutant NSCLCs. Eighteen eligible studies (1986 EGFR-mutant NSCLCs) were included in this meta-analysis. Positive PD-L1 expression correlated with lower objective response rate of EGFR-TKI treatment (odds ratio [95% confidence interval {CI}] = 0.52 [0.28–0.98], P = .043), while PFS (adjusted HR [95% CI] = 1.49 [0.96–1.89], P = .332) and OS (HR [95% CI] = 1.24 [0.70–2.20], P = .456) of EGFR-TKI treatment did not correlated with PD-L1 status. Furthermore, PD-L1 expression was not a predictive biomarker for the OS (HR [95% CI] = 1.43 [0.98–2.08], P = .062) in overall EGFR-mutant cohort. Positive PD-L1 expression indicated a higher incidence of primary resistance, but did not correlate with the PFS or OS of EGFR-TKI therapy. In addition, PD-L1 expression was unlikely a predictive biomarker for prognosis of EGFR-mutant NSCLCs.

Published
2021

139. A fast CU Size Decision Algorithm for 3D-HEVC

Author

Wang Yubing, Wang Yongfang, and Shi Yawen

Subjects
Engineering (General). Civil engineering (General), TA1-2040
Abstract

The emerging 3D-HEVC has achieved the highest coding efficiency but requires a very high computational complexity. To speed up the encoding process for the dependent texture views, we propose a fast CU depth range selection algorithm by jointly making use of the interview and temporal-spatial correlations. Firstly, adaptive correlation weights are proposed to predict coding unit(CU) depth range and skip some specific depth levels rarely used in independent view, the previous frame and neighboring CUs. Besides, a new early termination algorithm is proposed to further reduce the coding time. Experimental results demonstrate that the proposed method saves about 56% coding time on average compared to HTM with maintaining the similar video quality.

Published
2016
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140. The bHLH transcription factor PPLS1 regulates the color of pulvinus and leaf sheath in foxtail millet (Setaria italica)

Author

Li Zhiyong, Yan Zhang, Bai Hui, Dayong Li, Zhi-Ping Dong, Song Zhenjun, Min Liu, Wang Yongfang, Jianzhang Quan, Xianghong Wu, Jifang Ma, Jun Zhou, and Xue Liu

Subjects
0106 biological sciences, Chlorophyll, Setaria, Setaria Plant, Color, Biology, 01 natural sciences, Polymorphism, Single Nucleotide, Anthocyanins, Transactivation, Gene Expression Regulation, Plant, Botany, Genetics, Basic Helix-Loop-Helix Transcription Factors, Pulvinus, MYB, Transcription factor, Gene, Phylogeny, Plant Proteins, fungi, food and beverages, Computational Biology, General Medicine, biology.organism_classification, Phenotype, Foxtail, Transcription Factor Gene, Agronomy and Crop Science, 010606 plant biology & botany, Biotechnology, Transcription Factors
Abstract

The bHLH transcription factor, PPLS1, interacts with SiMYB85 to control the color of pulvinus and leaf sheath by regulating anthocyanin biosynthesis in foxtail millet (Setaria italica). Foxtail millet (Setaria italica), a self-pollinated crop with numerous small florets, is difficult for cross-pollination. The color of pulvinus and leaf sheath with purple being dominant to green is an indicative character and often used for screening authentic hybrids in foxtail millet crossing. Deciphering molecular mechanism controlling this trait would greatly facilitate genetic improvement of cultivars in foxtail millet. Here, using the F2 bulk specific-locus amplified fragment sequencing approach, we mapped the putative causal gene for the purple color of pulvinus and leaf sheath (PPLS) trait to a 100 Kb region on chromosome 7. Expression analyses of the 15 genes in this region revealed that Seita.7G195400 (renamed here as PPLS1) was differentially expressed between purple and green cultivars. PPLS1 encodes a bHLH transcription factor and is localized in the nucleus with a transactivation activity. Furthermore, we observed that expression of a MYB transcription factor gene, SiMYB85 (Seita.4G086300) involved in anthocyanin biosynthesis, shows a totally positive association with that of PPLS1. Heterologous co-expression of both PPLS1 and SiMYB85 in tobacco leaves led to elevated anthocyanin accumulation and expression of some anthocyanin-related genes. Furthermore, PPLS1 physically interacts with SiMYB85. Taken together, our results suggest that PPLS1 interacts with SiMYB85 to control the color of pulvinus and leaf sheath by regulating anthocyanin biosynthesis in foxtail millet.

Published
2019

144. The Secular Trends of the Maternal Near Miss Ratio in China, 2012-2018

Author

Song, Ci, primary, Zhang, Yanfang, additional, Lin, Yuan, additional, Ge, Xiaoyun, additional, Wang, Yongfang, additional, Sun, Lu, additional, Zhou, Wenlong, additional, Rui, Xiaoyun, additional, Sun, Haiping, additional, Dong, Yan, additional, Chu, Zhiping, additional, Zhao, Na, additional, Chen, Liping, additional, Su, Min, additional, Du, Jiangbo, additional, Jin, Guangfu, additional, Ma, Hongxia, additional, Wang, Shui, additional, Shen, Hongbing, additional, Jiang, Xiaoqing, additional, and Hu, Zhibin, additional

Published
2021
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