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961 results on '"Wang, Huizhen"'

102. A new approach to prepare Polyethylene Glycol Allyl Glycidyl Ether

Author

Wang Huizhen, Xie Ruiyang, Chen Mingjun, Deng Weihao, Zhang Kaixin, and Liu Jiaqin

Subjects
Environmental sciences, GE1-350
Abstract

The polyethylene glycol allyl glycidyl ether (PGAGE) is an important intermediate for preparing silicone softener that can be synthesized from allyl alcohol polyoxyethylene ether and epichlorohydrin (ECH). The performance parameters including the concentration of ECH, initial boron trifluoride diethyl etherate (BFEE) as well as CaCl2 quality were investigated respectively. The optimum process parameters which can get high capping and low by-product rate are as follows: the ECH concentration is 2.0 M, the initial BFEE concentration is 1.65mM, and the CaCl2 dosage is 1.65g/L. Under these conditions, the maximal yield can be improved to 91.36%, the percent of capping rate is higher than 98.16%, the residual concentration of F-is only 0.63 mg/L.

Published
2021
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108. Linc279227 contributes to mitochondrial dysfunction in high glucose-treated mouse renal tubular epithelial cells

Author

Qi, Chunfang, primary, Liang, Tiantian, additional, Lin, Jinxin, additional, Xie, Jianteng, additional, Cao, Dan, additional, Wang, Huizhen, additional, Li, Qiuling, additional, Li, Shenheng, additional, Li, Jing, additional, Zhang, Yifan, additional, Wang, Yanhui, additional, Li, Sheng, additional, Chen, Zujiao, additional, Yau, Hokhim, additional, Lin, Shaochun, additional, Zhang, Shaogui, additional, Liu, Shuangxin, additional, Liang, Xinling, additional, Zhang, Liang, additional, and Wang, Wenjian, additional

Published
2023
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109. Bridging the Granularity Gap for Acoustic Modeling

Author

Xu, Chen, primary, Zhang, Yuhao, additional, Jiao, Chengbo, additional, Liu, Xiaoqian, additional, Hu, Chi, additional, Zeng, Xin, additional, Xiao, Tong, additional, Ma, Anxiang, additional, Wang, Huizhen, additional, and Zhu, Jingbo, additional

Published
2023
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127. A Density-Based Re-ranking Technique for Active Learning for Data Annotations

Author

Zhu, Jingbo, Wang, Huizhen, Tsou, Benjamin K., Hutchison, David, Series editor, Kanade, Takeo, Series editor, Kittler, Josef, Series editor, Kleinberg, Jon M., Series editor, Mattern, Friedemann, Series editor, Mitchell, John C., Series editor, Naor, Moni, Series editor, Nierstrasz, Oscar, Series editor, Pandu Rangan, C., Series editor, Steffen, Bernhard, Series editor, Sudan, Madhu, Series editor, Terzopoulos, Demetri, Series editor, Tygar, Doug, Series editor, Vardi, Moshe Y., Series editor, Weikum, Gerhard, Series editor, Goebel, Randy, editor, Siekmann, Jörg, editor, Wahlster, Wolfgang, editor, Li, Wenjie, editor, and Mollá-Aliod, Diego, editor

Published
2009
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129. A Dynamic Programming Model for Text Segmentation Based on Min-Max Similarity

Author

Ye, Na, Zhu, Jingbo, Zheng, Yan, Ma, Matthew Y., Wang, Huizhen, Zhang, Bin, Hutchison, David, editor, Kanade, Takeo, editor, Kittler, Josef, editor, Kleinberg, Jon M., editor, Mattern, Friedemann, editor, Mitchell, John C., editor, Naor, Moni, editor, Nierstrasz, Oscar, editor, Pandu Rangan, C., editor, Steffen, Bernhard, editor, Sudan, Madhu, editor, Terzopoulos, Demetri, editor, Tygar, Doug, editor, Vardi, Moshe Y., editor, Weikum, Gerhard, editor, Li, Hang, editor, Liu, Ting, editor, Ma, Wei-Ying, editor, Sakai, Tetsuya, editor, Wong, Kam-Fai, editor, and Zhou, Guodong, editor

Published
2008
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130. Multi-Scale Model for the Aging Performance of Particle-Filled Polymer Composites.

Author

Fang, Congli, Wang, Huizhen, Zhang, Yujiao, Zhang, Minghua, Shen, Tao, and Du, Jianke

Subjects
*MULTISCALE modeling, *DENSITY matrices, *POLYMERS, *ACCELERATED life testing, *ELASTIC modulus, *AGING
Abstract

In this study, we developed a novel multi-scale model to predict the aging performance of particle-filled polymer composites (PFPCs) under thermo-oxidative aging conditions. To investigate the aging behavior, high-temperature accelerated aging tests were conducted in combination with macroscopic and microscopic characterization. At the microscopic level, the crosslinking density of the polymer matrix is calculated using the closed-loop chain reaction of polymer oxidation. In addition, the theory of polymer physics was used to determine the relationship between crosslinking density and elastic modulus. Relationships between elastic modulus and dewetting strain were analyzed at the macroscopic level. Based on the observations and analyses, a multi-scale model was developed to predict the aging performance of PFPCs. The predicted results show good agreement with the test results, which verifies the reliability of the model. [ABSTRACT FROM AUTHOR]

Published
2023
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131. Identification of follicle‐stimulating hormone‐responsive genes in Sertoli cells during early postnatal mouse testis development.

Author

Wang, Huizhen, Liu, Zhenghui, Larsen, Mark, Hastings, Richard, Gunewardena, Sumedha, and Kumar, T. Rajendra

Subjects
*SERTOLI cells, *SPERMATOGENESIS, *TESTIS development, *LEYDIG cells, *GERM cells, *CELL cycle
Abstract

Background: In the mouse testis, Sertoli cells rapidly divide during a narrow window of time pre‐pubertally and differentiate thereafter. The number of Sertoli cells determines the testis size and germ cell‐carrying capacity. Follicle‐stimulating hormone (FSH) binds its cognate FSH‐receptors expressed on Sertoli cells and acts as a mitogen to regulate their proliferation. Fshb−/− mutant adult male mice have reduced Sertoli cell number and testis size and reduced sperm number and motility. However, FSH‐responsive genes in early postnatal mouse Sertoli cells are unknown. Objectives: To identify FSH‐responsive genes in early postnatal mouse Sertoli cells. Materials and methods: A fluorescence‐activated cell sorting method was developed to rapidly purify Sertoli cells from control and Fshb−/− mice carrying a Sox9 GfpKI allele. These pure Sertoli cells were used for large‐scale gene expression analyses. Results: We show that mouse Sertoli cells rarely divide beyond postnatal day 7. Our in vivo BrdU labeling studies indicate loss of FSH results in a 30% reduction in Sertoli cell proliferation in mice at 5 days of age. Flowsorted GFP+ Sertoli cells with maximal Fshr expression were 97%‐98% pure and mostly devoid of Leydig and germ cells as assessed by Taqman qPCR quantification of gene expression and immunolabeling of the corresponding cell‐specific markers. Large‐scale gene expression analysis identified several differentially regulated genes in flow‐sorted GFP+ Sertoli cells obtained from testis of control and Fshb−/− mice at 5 days of age. The top 25 networks identified by pathway analysis include those related to the cell cycle, cell survival and most importantly, carbohydrate and lipid metabolism and molecular transport. Discussion: Several of the FSH‐responsive genes identified in this study could serve as useful markers for Sertoli cell proliferation in normal physiology, toxicant‐induced Sertoli cell/testis injury, and other pathological conditions. Conclusion: Our studies reveal that FSH‐regulates macromolecular metabolism and molecular transport networks of genes in early postnatal Sertoli cells most likely in preparation for establishment of functional associations with germ cells to successfully coordinate spermatogenesis. [ABSTRACT FROM AUTHOR]

Published
2023
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132. Discrimination-Based Feature Selection for Multinomial Naïve Bayes Text Classification

Author

Zhu, Jingbo, Wang, Huizhen, Zhang, Xijuan, Hutchison, David, editor, Kanade, Takeo, editor, Kittler, Josef, editor, Kleinberg, Jon M., editor, Mattern, Friedemann, editor, Mitchell, John C., editor, Naor, Moni, editor, Nierstrasz, Oscar, editor, Pandu Rangan, C., editor, Steffen, Bernhard, editor, Sudan, Madhu, editor, Terzopoulos, Demetri, editor, Tygar, Dough, editor, Vardi, Moshe Y., editor, Weikum, Gerhard, editor, Carbonell, Jaime G., editor, Siekmann, Jörg, editor, Matsumoto, Yuji, editor, Sproat, Richard W., editor, Wong, Kam-Fai, editor, and Zhang, Min, editor

Published
2006
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133. Important Factors Controlling Gibberellin Homeostasis in Plant Height Regulation

Author

Zhou, Mei, Li, Yakun, Cheng, Zhuowei, Zheng, Xinyu, Cai, Chong, Wang, Huizhen, Lu, Kaixing, Zhu, Cheng, and Ding, Yanfei

Abstract

Plant height is an important agronomic trait that is closely associated with crop yield and quality. Gibberellins (GAs), a class of highly efficient plant growth regulators, play key roles in regulating plant height. Increasing reports indicate that transcriptional regulation is a major point of regulation of the GA pathways. Although substantial knowledge has been gained regarding GA biosynthetic and signaling pathways, important factors contributing to the regulatory mechanisms homeostatically controlling GA levels remain to be elucidated. Here, we provide an overview of current knowledge regarding the regulatory network involving transcription factors, noncoding RNAs, and histone modifications involved in GA pathways. We also discuss the mechanisms of interaction between GAs and other hormones in plant height development. Finally, future directions for applying knowledge of the GA hormone in crop breeding are described.

Published
2023
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137. Transcriptome and Network Analyses Reveal the Gene Set Involved in PST Accumulation and Responses to Toxic Alexandrium minutum Exposure in the Gills of Chlamys farreri

Author

Wang, Yujue, primary, Li, Moli, additional, Lou, Jiarun, additional, Xun, Xiaogang, additional, Chang, Lirong, additional, Wang, Yangrui, additional, Zhang, Quanqi, additional, Lu, Longfei, additional, Wang, Huizhen, additional, Hu, Jingjie, additional, Bao, Zhenmin, additional, and Hu, Xiaoli, additional

Published
2022
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148. Additional file 1 of Identification and evaluation of circulating small extracellular vesicle microRNAs as diagnostic biomarkers for patients with indeterminate pulmonary nodules

Author

Zheng, Di, Zhu, Yuming, Zhang, Jiyang, Zhang, Wei, Wang, Huizhen, Chen, Hao, Wu, Chunyan, Ni, Jian, Xu, Xiaoya, Nian, Baoning, Chen, Sheng, Wang, Beibei, Li, Xiaofang, Zhang, Yanan, Zhang, Jiatao, Zhong, Wenzhao, Xiong, Lei, Li, Fugen, Zhang, Dadong, Xu, Jianfang, and Jiang, Gening

Abstract

Additional file 1: Figure S1. Cohorts’ details and inclusion/exclusion criteria. Figure S2. Pathology subtypes of the training (a), test (b), and external validation (c) cohorts. Figure S3. Representative pathological images of the benign and malignant pulmonary nodule subtypes. Malignant nodule subtypes: adenocarcinoma in situ (AIS), minimally invasive adenocarcinoma (MIA), and invasive adenocarcinoma (IA); Benign nodule subtypes: granulomas, atypical adenomatous hyperplasia (AAH), hamartoma, cyst, fibrosis, organizing pneumonias (OP). Magnification, ×400; Formalin Fixed Paraffin-Embedded (FFPE) tissues. Figure S4. CirsEV-miR model performance in the test cohort and the external cohort. (a) Circulating sEV miRNA heatmap of the test cohort by unsupervised hierarchical clustering. (b) ROC curve of the CirsEV-miR model in the test cohort. (c) The CirsEV-miR scores of benign and malignant PNs in the test cohort. (d) ROC curve of the CirsEV-miR model in the external validation cohort. (e) The CirsEV-miR scores of healthy people and patients with benign or malignant PNs. (f) Expression level of the five miRNAs used in CirsEV-miR model. For each group n = 13. All data is presented with mean ± SD, except let-7b-3p which is presented with mean ± SEM. *p

Published
2022
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