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101. Step-Counting Accuracy of a Commercial Smartwatch in Mild-to-Moderate PD Patients and Effect of Spatiotemporal Gait Parameters, Laterality of Symptoms, Pharmacological State, and Clinical Variables

Author

Bianchini, Edoardo, primary, Caliò, Bianca, additional, Alborghetti, Marika, additional, Rinaldi, Domiziana, additional, Hansen, Clint, additional, Vuillerme, Nicolas, additional, Maetzler, Walter, additional, and Pontieri, Francesco E., additional

Published
2022
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106. Digitally supported shared decision-making and treat-to-target in rheumatology: a qualitative study embedded in a multicenter randomized controlled trial

Author

Muehlensiepen, Felix, primary, May, Susann, additional, Hadaschik, Katharina, additional, Vuillerme, Nicolas, additional, Heinze, Martin, additional, Grahammer, Manuel, additional, Labinsky, Hannah, additional, Boeltz, Sebastian, additional, Detert, Jacqueline, additional, Petersen, Jana, additional, Krönke, Gerhard, additional, Schett, Georg, additional, and Knitza, Johannes, additional

Published
2022
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107. Self-collection of capillary blood and saliva to determine COVID-19 vaccine immunogenicity in patients with immune-mediated inflammatory diseases and health professionals

Author

Schmetzer, Caroline, primary, Vogt, Ekaterina, additional, Stellar, Laura, additional, Godonou, Elie-Tino, additional, Liphardt, Anna-Maria, additional, Muehlensiepen, Felix, additional, Vuillerme, Nicolas, additional, Hueber, Axel J., additional, Kleyer, Arnd, additional, Krönke, Gerhard, additional, Schett, Georg, additional, Simon, David, additional, and Knitza, Johannes, additional

Published
2022
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110. Serious Game as New Health Telematics Tool for Patient Therapy Education: Example of Obesity and Type 2 Diabetes

Author

Demongeot, Jacques, Elena, Adrien, Taramasco, Carla, Vuillerme, Nicolas, Hutchison, David, editor, Kanade, Takeo, editor, Kittler, Josef, editor, Kleinberg, Jon M., editor, Mattern, Friedemann, editor, Mitchell, John C., editor, Naor, Moni, editor, Nierstrasz, Oscar, editor, Pandu Rangan, C., editor, Steffen, Bernhard, editor, Sudan, Madhu, editor, Terzopoulos, Demetri, editor, Tygar, Doug, editor, Vardi, Moshe Y., editor, Weikum, Gerhard, editor, Biswas, Jit, editor, Kobayashi, Hisato, editor, Wong, Lawrence, editor, Abdulrazak, Bessam, editor, and Mokhtari, Mounir, editor

Published
2013
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111. Ambient Assistive Healthcare and Wellness Management – Is 'The Wisdom of the Body' Transposable to One’s Home?

Author

Franco, Céline, Diot, Bruno, Fleury, Anthony, Demongeot, Jacques, Vuillerme, Nicolas, Hutchison, David, editor, Kanade, Takeo, editor, Kittler, Josef, editor, Kleinberg, Jon M., editor, Mattern, Friedemann, editor, Mitchell, John C., editor, Naor, Moni, editor, Nierstrasz, Oscar, editor, Pandu Rangan, C., editor, Steffen, Bernhard, editor, Sudan, Madhu, editor, Terzopoulos, Demetri, editor, Tygar, Doug, editor, Vardi, Moshe Y., editor, Weikum, Gerhard, editor, Biswas, Jit, editor, Kobayashi, Hisato, editor, Wong, Lawrence, editor, Abdulrazak, Bessam, editor, and Mokhtari, Mounir, editor

Published
2013
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112. Eigenständige Entnahme von Kapillarblut durch Patient:innen mit systemischen rheumatischen Erkrankungen – eine qualitative Interviewstudie zur Exploration der Patient:innen- und Versorger:innen-Perspektive

Author

Mühlensiepen, Felix, May, Susann, Zarbl, Joshua, Vogt, Ekatarina, Hadaschik, Katharina, Heinze, Martin, Böltz, Sebastian, Labinsky, Hannah, Bendzuck, Gerlinde, Korinth, Marianne, Elling-Audersch, Corinna, Vuillerme, Nicolas, Schett, Georg, Krönke, Gerhard, and Knitza, Johannes

Subjects
Medicine and health
Abstract

Einleitung: Die kapillare Blutentnahme durch Patienten ist in vielen anderen Fachbereichen bereits fest etabliert. Eine Entnahme am Oberarm mittels modernen Geräten (TASSO+, TAP II) ermöglicht eine noch einfachere und fast schmerzlose Anwendung und könnte die Versorgung von rheumatologischen [zum vollständigen Text gelangen Sie über die oben angegebene URL]

Published
2022
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113. Machine learning-based improvement of an online rheumatology referral and triage system

Author

Knitza, Johannes, Janousek, Lena, Kluge, Felix, von der Decken, Cay Benedikt, Kleinert, Stefan, Vorbrüggen, Wolfgang, Kleyer, Arnd, Simon, David, Hueber, Axel J., Muehlensiepen, Felix, Vuillerme, Nicolas, Schett, Georg, Eskofier, Bjoern M., Welcker, Martin, and Bartz-Bazzanella, Peter

Subjects
ddc:610, General Medicine
Abstract

IntroductionRheport is an online rheumatology referral system allowing automatic appointment triaging of new rheumatology patient referrals according to the respective probability of an inflammatory rheumatic disease (IRD). Previous research reported that Rheport was well accepted among IRD patients. Its accuracy was, however, limited, currently being based on an expert-based weighted sum score. This study aimed to evaluate whether machine learning (ML) models could improve this limited accuracy.Materials and methodsData from a national rheumatology registry (RHADAR) was used to train and test nine different ML models to correctly classify IRD patients. Diagnostic performance was compared of ML models and the current algorithm was compared using the area under the receiver operating curve (AUROC). Feature importance was investigated using shapley additive explanation (SHAP).ResultsA complete data set of 2265 patients was used to train and test ML models. 30.5% of patients were diagnosed with an IRD, 69.3% were female. The diagnostic accuracy of the current Rheport algorithm (AUROC of 0.534) could be improved with all ML models, (AUROC ranging between 0.630 and 0.737). Targeting a sensitivity of 90%, the logistic regression model could double current specificity (17% vs. 33%). Finger joint pain, inflammatory marker levels, psoriasis, symptom duration and female sex were the five most important features of the best performing logistic regression model for IRD classification.ConclusionIn summary, ML could improve the accuracy of a currently used rheumatology online referral system. Including further laboratory parameters and enabling individual feature importance adaption could increase accuracy and lead to broader usage.

Published
2022

115. Remote self-collection of capillary blood using upper arm devices for autoantibody analysis in patients with immune-mediated inflammatory rheumatic diseases

Author

Zarbl, Joshua, primary, Eimer, Ekaterina, additional, Gigg, Camilla, additional, Bendzuck, Gerlinde, additional, Korinth, Marianne, additional, Elling-Audersch, Corinna, additional, Kleyer, Arnd, additional, Simon, David, additional, Boeltz, Sebastian, additional, Krusche, Martin, additional, Mucke, Johanna, additional, Muehlensiepen, Felix, additional, Vuillerme, Nicolas, additional, Krönke, Gerhard, additional, Schett, Georg, additional, and Knitza, Johannes, additional

Published
2022
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119. Pervasive Informatics and Persistent Actimetric Information in Health Smart Homes

Author

Fouquet, Yannick, Vuillerme, Nicolas, Demongeot, Jacques, Hutchison, David, Series editor, Kanade, Takeo, Series editor, Kittler, Josef, Series editor, Kleinberg, Jon M., Series editor, Mattern, Friedemann, Series editor, Mitchell, John C., Series editor, Naor, Moni, Series editor, Nierstrasz, Oscar, Series editor, Pandu Rangan, C., Series editor, Steffen, Bernhard, Series editor, Sudan, Madhu, Series editor, Terzopoulos, Demetri, Series editor, Tygar, Doug, Series editor, Vardi, Moshe Y., Series editor, Weikum, Gerhard, Series editor, Mokhtari, Mounir, editor, Khalil, Ismail, editor, Bauchet, Jérémy, editor, Zhang, Daqing, editor, and Nugent, Chris, editor

Published
2009
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120. Contributors

Author

Adam, Clayton, primary, Ambrosi, Davide, additional, Anderson, Peter, additional, Avril, Stéphane, additional, Babarenda Gamage, Thiranja P., additional, Badel, Pierre, additional, Bellini, Chiara, additional, Blemker, Silvia S., additional, Boubaker, Mohamed Bader, additional, Bovendeerd, Peter H.M., additional, Bucki, Marek, additional, Calvo, Begonã, additional, Cannard, Francis, additional, Chabanas, Matthieu, additional, Chagnon, Grégory, additional, Chatelin, Simon, additional, Courtecuisse, Hadrien, additional, Curt, Nicolas, additional, Cyron, Christian J., additional, Delhaas, Tammo, additional, Delingette, Hervé, additional, Di Martino, Elena S., additional, Dumas, Raphaël, additional, Dupuis, Olivier, additional, Favier, Denis, additional, Fels, Sidney, additional, Fereidoonnezhad, Behrooz, additional, Finet, Gérard, additional, Flynn, Cormac, additional, Frauziols, Fanny, additional, Ganghoffer, Jean-François, additional, Garcia, Alberto, additional, Gasser, Thomas C., additional, Gharib, Ahmed M., additional, Glass, Paul, additional, Gregersen, Hans, additional, Harandi, Negar M., additional, Hermant, Nicolas, additional, Hernández-Gascón, Belén, additional, Ho, Andrew, additional, Holzapfel, Gerhard A., additional, Humphrey, Jay D., additional, Lafon, Yoann, additional, Laporte, Sébastien, additional, Liao, Donghua, additional, Luboz, Vincent, additional, Malvè, Mauro, additional, Marchesseau, Stéphanie, additional, Martiel, Jean-Louis, additional, Moisik, Scott, additional, Molimard, Jérôme, additional, Morin, Fanny, additional, Nash, Martyn P., additional, Navarro, Laurent, additional, Nazari, Mohammad Ali, additional, Nielsen, Poul M.F., additional, Ohayon, Jacques, additional, Oomens, Cees W.J., additional, Payan, Yohan, additional, Peña, Estefanía, additional, Perrier, Pascal, additional, Perrier, Antoine, additional, Peters, Gerrit W.M., additional, Pettigrew, Roderic I., additional, Pioletti, Dominique P., additional, Pluijmert, Marieke, additional, Rakotomanana, Lalao, additional, Rohan, Pierre-Yves, additional, Rouch, Philippe, additional, Sánchez, C. Antonio, additional, Skalli, Wafa, additional, Stavness, Ian, additional, Stelletta, Julien, additional, Tang, Keyi, additional, Van den Abbeele, Maxim, additional, Vijven, Marc van, additional, Vogel, Arne, additional, Vuillerme, Nicolas, additional, Wilson, John S., additional, Yazdani, Saami K., additional, Zara, Florence, additional, and Zhao, Jingbo, additional

Published
2017
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121. Biomechanical Modeling of the Foot

Author

Perrier, Antoine, primary, Luboz, Vincent, additional, Bucki, Marek, additional, Cannard, Francis, additional, Vuillerme, Nicolas, additional, and Payan, Yohan, additional

Published
2017
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124. Decreasing Internal Focus of Attention Improves Postural Control during Quiet Standing in Young Healthy Adults

Author

Nafati, Gilel and Vuillerme, Nicolas

Abstract

This experiment was designed to investigate whether and how decreasing the amount of attentional focus invested in postural control could affect bipedal postural control. Twelve participants were asked to stand upright as immobile as possible on a force platform in one control condition and one cognitive condition. In the latter condition, they performed a short-term digit-span memory task. Decreased center-of-gravity displacements and decreased center-of-foot-pressure displacements minus center-of-gravity displacements were observed in the cognitive condition relative to the control condition. These results suggest that shifting the attentional focus away from postural control by executing a concurrent attention-demanding task could increase postural performance and postural efficiency. (Contains 3 figures.)

Published
2011

127. Review and Analysis of German Mobile Apps for Inflammatory Bowel Disease Management Using the Mobile Application Rating Scale: Systematic Search in App Stores and Content Analysis

Author

Gerner, Maximilian, primary, Vuillerme, Nicolas, additional, Aubourg, Timothée, additional, Messner, Eva-Maria, additional, Terhorst, Yannik, additional, Hörmann, Verena, additional, Ganzleben, Ingo, additional, Schenker, Hannah, additional, Schett, Georg, additional, Atreya, Raja, additional, Neurath, Markus F, additional, Knitza, Johannes, additional, and Orlemann, Till, additional

Published
2022
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131. Patient's Perception of Digital Symptom Assessment Technologies in Rheumatology: Results From a Multicentre Study

Author

Knitza, Johannes, Muehlensiepen, Felix, Ignatyev, Yuriy, Fuchs, Franziska, Mohn, Jacob, Simon, David, Kleyer, Arnd, Fagni, Filippo, Boeltz, Sebastian, Morf, Harriet, Bergmann, Christina, Labinsky, Hannah, Vorbrüggen, Wolfgang, Ramming, Andreas, Distler, Jörg H. W., Bartz-Bazzanella, Peter, Vuillerme, Nicolas, Schett, Georg, Welcker, Martin, and Hueber, Axel J.

Subjects
Male, Rheumatology, Artificial Intelligence, Public Health, Environmental and Occupational Health, Humans, Female, Perception, Prospective Studies, ddc:610, Middle Aged, Symptom Assessment
Abstract

IntroductionAn increasing number of digital tools, including dedicated diagnostic decision support systems (DDSS) exist to better assess new symptoms and understand when and where to seek medical care. The aim of this study was to evaluate patient's previous online assessment experiences and to compare the acceptability, usability, usefulness and potential impact of artificial intelligence (AI)-based symptom checker (Ada) and an online questionnaire-based self-referral tool (Rheport).Materials and MethodsPatients newly presenting to three German secondary rheumatology outpatient clinics were randomly assigned in a 1:1 ratio to complete consecutively Ada or Rheport in a prospective non-blinded multicentre controlled crossover randomized trial. DDSS completion time was recorded by local study personnel and perceptions on DDSS and previous online assessment were collected through a self-completed study questionnaire, including usability measured with the validated System Usability Scale (SUS).Results600 patients (median age 52 years, 418 women) were included. 277/600 (46.2%) of patients used an online search engine prior to the appointment. The median time patients spent assessing symptoms was 180, 7, and 8 min, respectively using online using search engines, Ada and Rheport. 111/275 (40.4%), 266/600 (44.3%) and 395/600 (65.8%) of patients rated the respective symptom assessment as very helpful or helpful, using online search engines, Ada and Rheport, respectively. Usability of both diagnostic decision support systems (DDSS) was “good” with a significantly higher mean SUS score (SD) of Rheport 77.1/100 (16.0) compared to Ada 74.4/100 (16.8), (p < 0.0001). In male patients, usability of Rheport was rated higher than Ada (p = 0.02) and the usability rating of older (52 years ≥) patients of both DDSS was lower than in younger participants (p = 0.005). Both effects were independent of each other. 440/600 (73.3%) and 475/600 (79.2%) of the patients would recommend Ada and Rheport to friends and other patients, respectively.ConclusionIn summary, patients increasingly assess their symptoms independently online, however only a minority used dedicated symptom assessment websites or DDSS. DDSS, such as Ada an Rheport are easy to use, well accepted among patients with musculoskeletal complaints and could replace online search engines for patient symptom assessment, potentially saving time and increasing helpfulness.

Published
2022

132. Additional file 2 of Accuracy and tolerability of self-sampling of capillary blood for analysis of inflammation and autoantibodies in rheumatoid arthritis patients—results from a randomized controlled trial

Author

Knitza, Johannes, Tascilar, Koray, Vuillerme, Nicolas, Eimer, Ekaterina, Matusewicz, Paul, Corte, Giulia, Schuster, Louis, Aubourg, Timothée, Bendzuck, Gerlinde, Korinth, Marianne, Elling-Audersch, Corinna, Kleyer, Arnd, Boeltz, Sebastian, Hueber, Axel J., Krönke, Gerhard, Schett, Georg, and Simon, David

Abstract

Additional file 2: Fig. S2. Intraclass correlation coefficients and 95% confidence interval by group and analyte

Published
2022
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133. Additional file 3 of Digitally-supported patient-centered asynchronous outpatient follow-up in rheumatoid arthritis - an explorative qualitative study

Author

Stenzel, Ramona, Hadaschik, Katharina, May, Susann, Grahammer, Manuel, Labinsky, Hannah, Welcker, Martin, Hornig, Johannes, Bendzuck, Gerlinde, Elling-Audersch, Corinna, Erstling, Ulrike, Korbanka, Patricia Steffens, Vuillerme, Nicolas, Heinze, Martin, Krönke, Gerhard, Schett, Georg, Pecher, Ann-Christin, Krusche, Martin, Mucke, Johanna, Knitza, Johannes, and Muehlensiepen, Felix

Abstract

Supplementary Material 3

Published
2022
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134. Additional file 1 of Digitally-supported patient-centered asynchronous outpatient follow-up in rheumatoid arthritis - an explorative qualitative study

Author

Stenzel, Ramona, Hadaschik, Katharina, May, Susann, Grahammer, Manuel, Labinsky, Hannah, Welcker, Martin, Hornig, Johannes, Bendzuck, Gerlinde, Elling-Audersch, Corinna, Erstling, Ulrike, Korbanka, Patricia Steffens, Vuillerme, Nicolas, Heinze, Martin, Krönke, Gerhard, Schett, Georg, Pecher, Ann-Christin, Krusche, Martin, Mucke, Johanna, Knitza, Johannes, and Muehlensiepen, Felix

Abstract

Supplementary Material 1

Published
2022
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135. Additional file 2 of Digitally-supported patient-centered asynchronous outpatient follow-up in rheumatoid arthritis - an explorative qualitative study

Author

Stenzel, Ramona, Hadaschik, Katharina, May, Susann, Grahammer, Manuel, Labinsky, Hannah, Welcker, Martin, Hornig, Johannes, Bendzuck, Gerlinde, Elling-Audersch, Corinna, Erstling, Ulrike, Korbanka, Patricia Steffens, Vuillerme, Nicolas, Heinze, Martin, Krönke, Gerhard, Schett, Georg, Pecher, Ann-Christin, Krusche, Martin, Mucke, Johanna, Knitza, Johannes, and Muehlensiepen, Felix

Abstract

Supplementary Material 2

Published
2022
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138. Additional file 1 of Accuracy and tolerability of self-sampling of capillary blood for analysis of inflammation and autoantibodies in rheumatoid arthritis patients—results from a randomized controlled trial

Author

Knitza, Johannes, Tascilar, Koray, Vuillerme, Nicolas, Eimer, Ekaterina, Matusewicz, Paul, Corte, Giulia, Schuster, Louis, Aubourg, Timothée, Bendzuck, Gerlinde, Korinth, Marianne, Elling-Audersch, Corinna, Kleyer, Arnd, Boeltz, Sebastian, Hueber, Axel J., Krönke, Gerhard, Schett, Georg, and Simon, David

Abstract

Additional file 1: Fig. S1. Self-sampling feasibility results according to randomization arm

Published
2022
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140. Exploring acute effects of workplace warm-up intervention on pain, physical capacities, and productivity in agriculture: A study protocol.

Author

Larinier, Nicolas, Vuillerme, Nicolas, Jadaud, Alexandre, Malherbe, Solène, and Balaguier, Romain

Subjects
WORK environment, EVALUATION of medical care, ANALYSIS of variance, LABOR productivity, PAIN, CONFIDENCE intervals, FUNCTIONAL status, PHYSICAL activity, RANDOMIZED controlled trials, EMPLOYEES' workload, DESCRIPTIVE statistics, BLIND experiment, RESEARCH funding, STATISTICAL sampling, AGRICULTURAL laborers, WARMUP
Abstract

BACKGROUND: Physical activity programs at the workplace have shown positive results on physical capacities and pain for several years. Due to the duration of the training session or the need for an instructor, these supervised programs are rather difficult to implement. For this reason, numerous companies, especially companies in manual sectors, are turning to another solution, i.e. warm-up intervention before the work shift. These interventions present various advantages such as short duration and the possibility to perform exercises in working clothes. Surprisingly, while the positive effects of warm-up interventions on pain, performance, and physical and psychological capacities are expansively reported in the sport context, effects of workplace warm-up intervention are lacking. OBJECTIVE: The aim of this study is to assess the acute effects of three different warm-up interventions on physical (pain, strength, flexibility) and psychological (workload) functions and also on work-related outcomes (work performance, readiness to work) among vineyard workers. METHODS: A cluster randomized study will be implemented among French vineyard workers. Four groups of 30 participants will be constituted; corresponding to four different conditions: (1) hybrid warm-up intervention (HWU); (2) dynamic warm-up intervention (DWU); (3) stretching warm-up intervention (SWU); (4) no warm-up intervention (NWU). A total of 120 vineyard workers will be recruited to participate in the study. CONCLUSION: The results will provide more evidence about the short-term effects of warm-up interventions at the workplace and will provide more evidence on which warm-up modality is the most effective on pain, performance, and physical and psychological capacities among vineyard workers. [ABSTRACT FROM AUTHOR]

Published
2023
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141. Step-Counting Accuracy of a Commercial Smartwatch in Mild-to-Moderate PD Patients and Effect of Spatiotemporal Gait Parameters, Laterality of Symptoms, Pharmacological State, and Clinical Variables.

Author

Bianchini, Edoardo, Caliò, Bianca, Alborghetti, Marika, Rinaldi, Domiziana, Hansen, Clint, Vuillerme, Nicolas, Maetzler, Walter, and Pontieri, Francesco E.

Subjects
SMARTWATCHES, GAIT in humans, WRIST, PARKINSON'S disease, INTRACLASS correlation, LATERAL dominance, ANKLE, DEEP brain stimulation
Abstract

Commercial smartwatches could be useful for step counting and monitoring ambulatory activity. However, in Parkinson's disease (PD) patients, an altered gait, pharmacological condition, and symptoms lateralization may affect their accuracy and potential usefulness in research and clinical routine. Steps were counted during a 6 min walk in 47 patients with PD and 47 healthy subjects (HS) wearing a Garmin Vivosmart 4 (GV4) on each wrist. Manual step counting was used as a reference. An inertial sensor (BTS G-Walk), placed on the lower back, was used to compute spatial-temporal gait parameters. Intraclass correlation coefficient (ICC) and mean absolute percentage error (MAPE) were used for accuracy evaluation and the Spearman test was used to assess the correlations between variables. The GV4 overestimated steps in PD patients with only a poor-to-moderate agreement. The OFF pharmacological state and wearing the device on the most-affected body side led to an unacceptable accuracy. The GV4 showed an excellent agreement and MAPE in HS at a self-selected speed, but an unacceptable performance at a slow speed. In PD patients, MAPE was not associated with gait parameters and clinical variables. The accuracy of commercial smartwatches for monitoring step counting might be reduced in PD patients and further influenced by the pharmacological condition and placement of the device. [ABSTRACT FROM AUTHOR]

Published
2023
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145. Patient's Perception of Digital Symptom Assessment Technologies in Rheumatology: Results From a Multicentre Study

Author

Knitza, Johannes, primary, Muehlensiepen, Felix, additional, Ignatyev, Yuriy, additional, Fuchs, Franziska, additional, Mohn, Jacob, additional, Simon, David, additional, Kleyer, Arnd, additional, Fagni, Filippo, additional, Boeltz, Sebastian, additional, Morf, Harriet, additional, Bergmann, Christina, additional, Labinsky, Hannah, additional, Vorbrüggen, Wolfgang, additional, Ramming, Andreas, additional, Distler, Jörg H. W., additional, Bartz-Bazzanella, Peter, additional, Vuillerme, Nicolas, additional, Schett, Georg, additional, Welcker, Martin, additional, and Hueber, Axel J., additional

Published
2022
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150. TELERA—Asynchronous TELEmedicine for Patients With Rheumatoid Arthritis: Study Protocol for a Prospective, Multi-Center, Randomized Controlled Trial

Author

Mucke, Johanna, primary, Knitza, Johannes, additional, Muehlensiepen, Felix, additional, Grahammer, Manuel, additional, Stenzel, Ramona, additional, Simon, David, additional, Kleyer, Arnd, additional, Krönke, Gerhard, additional, Sharp, Charlotte, additional, Bendzuck, Gerlinde, additional, Korinth, Marianne, additional, Elling-Audersch, Corinna, additional, Vuillerme, Nicolas, additional, Schett, Georg, additional, Pecher, Ann-Christin, additional, and Krusche, Martin, additional

Published
2021
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