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842 results on '"Tucker, Andrew"'

101. 'Dear Evan Hansen': Mental illness designed by committee

Author

Tucker, Andrew

Subjects
Mental illness, News, opinion and commentary, Sports and fitness
Abstract

Byline: Andrew Tucker It's difficult to realize why this show is beloved. In all fairness, I haven't seen the stage show and am only talking about the film. So, if [...]

Published
2021

104. Abstract LB144: Overexpression of CD47 protects hypoimmune CAR T cells from innate immune cell killing

Author

Hu, Xiaomeng, primary, Dao, Mo, additional, White, Kathy, additional, Clarke, Ryan, additional, Landry, Sam, additional, Basco, Ron, additional, Gattis, Corie, additional, Tham, Eleonore, additional, Luo, Emily, additional, Tucker, Andrew, additional, Bandoro, Christopher, additional, Chu, Elaine, additional, Kim, Junmo, additional, Young, Chi, additional, Dowdle, William E., additional, Rebar, Edward J., additional, Fry, Terry J., additional, and Schrepfer, Sonja, additional

Published
2021
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105. Prevalence of Inflammatory Heart Disease Among Professional Athletes With Prior COVID-19 Infection Who Received Systematic Return-to-Play Cardiac Screening

Author

Martinez, Matthew W., primary, Tucker, Andrew M., additional, Bloom, O. Josh, additional, Green, Gary, additional, DiFiori, John P., additional, Solomon, Gary, additional, Phelan, Dermot, additional, Kim, Jonathan H., additional, Meeuwisse, Willem, additional, Sills, Allen K., additional, Rowe, Dana, additional, Bogoch, Isaac I., additional, Smith, Paul T., additional, Baggish, Aaron L., additional, Putukian, Margot, additional, and Engel, David J., additional

Published
2021
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106. Driver Psychology Latent Classes as Predictors of Traffic Incident Occurrence in Naturalistic Driving Study Data

Author

Sharmin, Sadia, Ivan, John N., Marsh, Kerry L., Paxton, Alexandra, and Tucker, Andrew

Abstract

Crash risk depends on several factors, driver factors being the most significant of all. Previous studies have tended to use roadway and driver demographic information to explain crash risk, overlooking driver psychological characteristics, which are also important for crash risk estimation. Crash data from police reports are available only for reportable crashes and do not detail driver characteristics or comparable information on driving activities. Naturalistic driving studies (NDSs) offer unique opportunities to obtain information about driver attributes, behavior, or other precrash factors for predicting crash occurrence. This study estimated NDS event-oriented models to evaluate the interaction between driver attributes and roadway environmental factors for predicting safety critical events. A latent class clustering approach was used to uncover categories of drivers by psychological, perceptual, and cognitive characteristics, and by driving experience. The results revealed four driver types: risk-taker, careful-impaired, careful-unimpaired, and distractible. These types were incorporated in mixed-effects binary logistic models, with roadway, traffic, and environmental variables to estimate and predict crash risk. The models that included driver factors more successfully predicted crash risk than those without. Risk-takers showed the highest probability of being in crashes. However, careful-impaired drivers—those whose impairments made it difficult to identify the location of another vehicle, visualize missing information, who had difficulties with visual–spatial perception and executive functioning—posed a higher crash risk in roadway conditions such as snow, lack of lane markings, and certain traffic operating conditions. The results point to novel avenues for educational and behavioral interventions to improve road safety.

Published
2023
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109. Impact of COVID-19 pandemic on mobility in ten countries and associated perceived risk for all transport modes

Author

Barbieri, Diego Maria, Lou, Baowen, Passavanti, Marco, Hui, Cang, Hoff, Inge, Lessa, Daniela Antunes, Sikka, Gaurav, Chang, Kevin, Gupta, Akshay, Fang, Kevin, Banerjee, Arunabha, Maharaj, Brij, Lam, Louisa, Ghasemi, Navid, Naik, Bhaven, Wang, Fusong, Mirhosseini, Ali Foroutan, Naseri, Sahra, Liu, Zhuangzhuang, Qiao, Yaning, Tucker, Andrew, Wijayaratna, Kasun, Peprah, Prince, Adomako, Solomon, Yu, Lei, Goswami, Shubham, Chen, Hao, Shu, Benan, Hessami, Amir, Abbas, Montasir M., Agarwal, Nithin, Rashidi, Taha Hossein, and Civil and Environmental Engineering

Abstract

The restrictive measures implemented in response to the COVID-19 pandemic have triggered sudden massive changes to travel behaviors of people all around the world. This study examines the individual mobility patterns for all transport modes (walk, bicycle, motorcycle, car driven alone, car driven in company, bus, subway, tram, train, airplane) before and during the restrictions adopted in ten countries on six continents: Australia, Brazil, China, Ghana, India, Iran, Italy, Norway, South Africa and the United States. This cross-country study also aims at understanding the predictors of protective behaviors related to the transport sector and COVID-19. Findings hinge upon an online survey conducted in May 2020 (N = 9,394). The empirical results quantify tremendous disruptions for both commuting and non-commuting travels, highlighting substantial reductions in the frequency of all types of trips and use of all modes. In terms of potential virus spread, airplanes and buses are perceived to be the riskiest transport modes, while avoidance of public transport is consistently found across the countries. According to the Protection Motivation Theory, the study sheds new light on the fact that two indicators, namely income inequality, expressed as Gini index, and the reported number of deaths due to COVID-19 per 100,000 inhabitants, aggravate respondents' perceptions. This research indicates that socio-economic inequality and morbidity are not only related to actual health risks, as well documented in the relevant literature, but also to the perceived risks. These findings document the global impact of the COVID-19 crisis as well as provide guidance for transportation practitioners in developing future strategies.

Published
2021

110. Geographical interventions into debates regarding 'men who have sex with men' (MSM).

Author

Tucker, Andrew

Subjects
*MEN who have sex with men, *ORPHANS, DEVELOPING countries
Abstract

While today ubiquitous in HIV/AIDS policy and programming, the conceptual category of 'men who have sex with men' (MSM) has come under sustained critique as a result of its limited explanatory power and inability to engage with social, cultural and community complexity. This article examines how geographers may add substantively to such critical debates and extend them in new ways across sites in the global South where the category is often deployed. It does this by considering the importance of place, varying local and international imperatives for the category, and implications of considering socio-spatial liminality to conceptualise men's experiences of HIV programming. [ABSTRACT FROM AUTHOR]

Published
2022
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113. Air pollution perception in ten countries during the COVID-19 pandemic

Author

Lou, Baowen, primary, Barbieri, Diego Maria, additional, Passavanti, Marco, additional, Hui, Cang, additional, Gupta, Akshay, additional, Hoff, Inge, additional, Lessa, Daniela Antunes, additional, Sikka, Gaurav, additional, Chang, Kevin, additional, Fang, Kevin, additional, Lam, Louisa, additional, Maharaj, Brij, additional, Ghasemi, Navid, additional, Qiao, Yaning, additional, Adomako, Solomon, additional, Foroutan Mirhosseini, Ali, additional, Naik, Bhaven, additional, Banerjee, Arunabha, additional, Wang, Fusong, additional, Tucker, Andrew, additional, Liu, Zhuangzhuang, additional, Wijayaratna, Kasun, additional, Naseri, Sahra, additional, Yu, Lei, additional, Chen, Hao, additional, Shu, Benan, additional, Goswami, Shubham, additional, Peprah, Prince, additional, Hessami, Amir, additional, Abbas, Montasir, additional, and Agarwal, Nithin, additional

Published
2021
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118. Blockade of IGF/IGF-1R signaling axis with soluble IGF-1R mutants suppresses the cell proliferation and tumor growth of human osteosarcoma

Author

Cao, Daigui, Lei, Yan, Ye, Zhenyu, Zhao, Ling, Wang, Hao, Zhang, Jing, He, Fang, Huang, Linjuan, Shi, Deyao, Liu, Qing, Ni, Na, Pakvasa, Mikhail, Wagstaff, William, Zhao, Xia, Fu, Kai, Tucker, Andrew B, Chen, Connie, Reid, Russell R, Haydon, Rex C, Luu, Hue H, He, Tong-Chuan, and Liao, Zhan

Subjects
Original Article
Abstract

Primary bone tumor, also known as osteosarcoma (OS), is the most common primary malignancy of bone in children and young adults. Current treatment protocols yield a 5-year survival rate of near 70% although approximately 80% of patients have metastatic disease at the time of diagnosis. However, long-term survival rates have remained virtually unchanged for nearly four decades, largely due to our limited understanding of the disease process. One major signaling pathway that has been implicated in human OS tumorigenesis is the insulin-like growth factor (IGF)/insulin-like growth factor-1 receptor (IGF1R) signaling axis. IGF1R is a heterotetrameric α2β2 receptor, in which the α subunits comprise the ligand binding site, whereas the β subunits are transmembrane proteins containing intracellular tyrosine kinase domains. Although numerous strategies have been devised to target IGF/IGF1R axis, most of them have failed in clinical trials due to the lack of specificity and/or limited efficacy. Here, we investigated whether a more effective and specific blockade of IGF1R activity in human OS cells can be accomplished by employing dominant-negative IGF1R (dnIGF1R) mutants. We engineered the recombinant adenoviruses expressing two IGF1R mutants derived from the α (aa 1-524) and β (aa 741-936) subunits, and found that either dnIGF1Rα and/or dnIGF1Rβ effectively inhibited cell migration, colony formation, and cell cycle progression of human OS cells, which could be reversed by exogenous IGF1. Furthermore, dnIGF1Rα and/or dnIGF1Rβ inhibited OS xenograft tumor growth in vivo, with the greatest inhibition of tumor growth shown by dnIGF1Rα. Mechanistically, the dnIGF1R mutants down-regulated the expression of PI3K/AKT and RAS/RAF/MAPK, BCL2, Cyclin D1 and most EMT regulators, while up-regulating pro-apoptotic genes in human OS cells. Collectively, these findings strongly suggest that the dnIGF1R mutants, especially dnIGF1Rα, may be further developed as novel anticancer agents that target IGF signaling axis with high specificity and efficacy.

Published
2020

119. Survey data regarding perceived air quality in Australia, Brazil, China, Ghana, India, Iran, Italy, Norway, South Africa, United States before and during Covid-19 restrictions

Author

Barbieri, Diego Maria, Lou, Baowen, Passavanti, Marco, Hui, Cang, Lessa, Daniela Antunes, Maharaj, Brij, Banerjee, Arunabha, Wang, Fusong, Chang, Kevin, Naik, Bhaven, Yu, Lei, Liu, Zhuangzhuang, Sikka, Gaurav, Tucker, Andrew, Mirhosseini, Ali Foroutan, Naseri, Sahra, Qiao, Yaning, Gupta, Akshay, Abbas, Montasir M., Fang, Kevin, Ghasemi, Navid, Peprah, Prince, Goswami, Shubham, Hessami, Amir, Agarwal, Nithin, Lam, Louisa, Adomako, Solomon, and Civil and Environmental Engineering

Subjects
Survey data, Air quality, COVID-19, Psychometric perception, Environmental pollution
Abstract

The dataset deals with the air quality perceived by citizens before and during the enforcement of COVID-19 restrictions in ten countries around the world: Australia, Brazil, China, Ghana, India, Iran, Italy, Norway, South Africa and the United States. An online survey conveniently translated into Chinese, English, Italian, Norwegian, Persian, Portuguese collected information regarding the perceived quality of air pollution according to a Likert scale. The questionnaire was distributed between 11-05-2020 and 31-05-2020 and 9 394 respondents took part. Both the survey and the dataset (stored in a Microsoft Excel Worksheet) are available in a public repository. The collected data offer the people's subjective perspectives related to the objective improvement in air quality occurred during the COVID-19 restrictions. Furthermore, the dataset can be used for research studies involving the reduction in air pollution as experienced, to a different extent, by populations of all the ten countries. Published version

Published
2020

123. Brock Weirather makes Pioneer history with a perfect game

Author

Tucker, Andrew

Subjects
News, opinion and commentary, Sports and fitness
Abstract

Byline: Andrew Tucker 'What's the secret to success today?' As he walked on to the field this past Sunday, April 25, Brock Weirather `21 asked his teammate Quentin Jehn `24 [...]

Published
2021

125. Prevalence of cardiovascular disease risk factors among National Football League players

Author

Tucker, Andrew M., Vogel, Robert A., Lincoln, Andrew E., Dunn, Reginald E., Ahrensfield, Debra C., Allen, Thomas W., Castle, Lon W., Heyer, Robert A., Pellman, Elliott J., Strollo, Patrick J., Jr., Wilson, Peter W.F., and Yates, Anthony P.

Subjects
Body mass index -- Risk factors, Cardiovascular diseases -- Causes of, Football players -- Health aspects
Abstract

The study aims to evaluate the prevalence of cardiovascular disease (CVD) among larger-size National Football League (NFL) players currently playing. The results indicate that larger or increased size measured by the body mass index (BMI) was associated with a higher risk of CVD, as can be seen in the case of larger-sized football players.

Published
2009

128. Impact of COVID-19 pandemic on mobility in ten countries and associated perceived risk for all transport modes

Author

Barbieri, Diego Maria, primary, Lou, Baowen, additional, Passavanti, Marco, additional, Hui, Cang, additional, Hoff, Inge, additional, Lessa, Daniela Antunes, additional, Sikka, Gaurav, additional, Chang, Kevin, additional, Gupta, Akshay, additional, Fang, Kevin, additional, Banerjee, Arunabha, additional, Maharaj, Brij, additional, Lam, Louisa, additional, Ghasemi, Navid, additional, Naik, Bhaven, additional, Wang, Fusong, additional, Foroutan Mirhosseini, Ali, additional, Naseri, Sahra, additional, Liu, Zhuangzhuang, additional, Qiao, Yaning, additional, Tucker, Andrew, additional, Wijayaratna, Kasun, additional, Peprah, Prince, additional, Adomako, Solomon, additional, Yu, Lei, additional, Goswami, Shubham, additional, Chen, Hao, additional, Shu, Benan, additional, Hessami, Amir, additional, Abbas, Montasir, additional, Agarwal, Nithin, additional, and Rashidi, Taha Hossein, additional

Published
2021
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129. Identification of prognostic signature based on the copy number variation (CNV) and expression in acute myeloid leukemia

Author

Niu, Changchun, primary, Wu, Di, additional, Li, Alexander J., additional, Qin, Kevin H., additional, Hu, Daniel A., additional, Wang, Eric J., additional, Tucker, Andrew Blake, additional, He, Fang, additional, Huang, Linjuan, additional, Wang, Hao, additional, Liu, Qing, additional, Ni, Na, additional, Shi, Deyao, additional, Zhao, Xia, additional, Wan, Yafang, additional, Li, Tian, additional, He, Tong-Chuan, additional, and Liao, Pu, additional

Published
2021
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135. Stem Cell-Friendly Scaffold Biomaterials: Applications for Bone Tissue Engineering and Regenerative Medicine

Author

Zhang, Yongtao, primary, Wu, Di, additional, Zhao, Xia, additional, Pakvasa, Mikhail, additional, Tucker, Andrew Blake, additional, Luo, Huaxiu, additional, Qin, Kevin H., additional, Hu, Daniel A., additional, Wang, Eric J., additional, Li, Alexander J., additional, Zhang, Meng, additional, Mao, Yukun, additional, Sabharwal, Maya, additional, He, Fang, additional, Niu, Changchun, additional, Wang, Hao, additional, Huang, Linjuan, additional, Shi, Deyao, additional, Liu, Qing, additional, Ni, Na, additional, Fu, Kai, additional, Chen, Connie, additional, Wagstaff, William, additional, Reid, Russell R., additional, Athiviraham, Aravind, additional, Ho, Sherwin, additional, Lee, Michael J., additional, Hynes, Kelly, additional, Strelzow, Jason, additional, He, Tong-Chuan, additional, and El Dafrawy, Mostafa, additional

Published
2020
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136. A survey dataset to evaluate the changes in mobility and transportation due to COVID-19 travel restrictions in Australia, Brazil, China, Ghana, India, Iran, Italy, Norway, South Africa, United States

Author

Barbieri, Diego Maria, primary, Lou, Baowen, additional, Passavanti, Marco, additional, Hui, Cang, additional, Lessa, Daniela Antunes, additional, Maharaj, Brij, additional, Banerjee, Arunabha, additional, Wang, Fusong, additional, Chang, Kevin, additional, Naik, Bhaven, additional, Yu, Lei, additional, Liu, Zhuangzhuang, additional, Sikka, Gaurav, additional, Tucker, Andrew, additional, Foroutan Mirhosseini, Ali, additional, Naseri, Sahra, additional, Qiao, Yaning, additional, Gupta, Akshay, additional, Abbas, Montasir, additional, Fang, Kevin, additional, Ghasemi, Navid, additional, Peprah, Prince, additional, Goswami, Shubham, additional, Hessami, Amir, additional, Agarwal, Nithin, additional, Lam, Louisa, additional, and Adomako, Solomon, additional

Published
2020
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137. Use of a Shock Tube Platform in the Replication of Blast Lung Injury.

Author

Gálvez Díaz-Rubio, F., Cendón Franco, D. A., Butler, Benjamin, Nguyen, Thuy-Tien, Williams, Alun, Tucker, Andrew, Proud, William G., and Brown, Katherine A.

Subjects
SHOCK tubes, LUNG injuries, PATHOLOGICAL physiology, ORGAN culture, SARS disease
Abstract

War and asymmetrical conflicts are becoming increasingly prevalent in the modern world. Due to improvements in conflict medicine, survivable injuries are now more severe than they once were. Therefore, it is now more important than ever that there exist scientific and engineering methods for replicating wartime injuries in the context of the laboratory. We have developed one such method: a shock tube platform for testing ex vivo samples of the porcine respiratory system. Using this platform, we can, to some extent, simulate the pathophysiological consequences of blast lung. This is a condition commonly present in victims of explosive blasts, both those due to typical armaments and Improvised Explosive Devices (IEDs). Presented here are the results of experiments conducted using porcine bronchiole tissue as ex vivo organ cultures. Data presented show epithelial damage, consistent with known trauma-induced cell injury that can lead to acute respiratory distress syndrome (ARDS). [ABSTRACT FROM AUTHOR]

Published
2021
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140. Survey data regarding perceived air quality in Australia, Brazil, China, Ghana, India, Iran, Italy, Norway, South Africa, United States before and during Covid-19 restrictions

Author

Barbieri, Diego Maria, primary, Lou, Baowen, additional, Passavanti, Marco, additional, Hui, Cang, additional, Lessa, Daniela Antunes, additional, Maharaj, Brij, additional, Banerjee, Arunabha, additional, Wang, Fusong, additional, Chang, Kevin, additional, Naik, Bhaven, additional, Yu, Lei, additional, Liu, Zhuangzhuang, additional, Sikka, Gaurav, additional, Tucker, Andrew, additional, Mirhosseini, Ali Foroutan, additional, Naseri, Sahra, additional, Qiao, Yaning, additional, Gupta, Akshay, additional, Abbas, Montasir, additional, Fang, Kevin, additional, Ghasemi, Navid, additional, Peprah, Prince, additional, Goswami, Shubham, additional, Hessami, Amir, additional, Agarwal, Nithin, additional, Lam, Louisa, additional, and Adomako, Solomon, additional

Published
2020
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142. Identification of Prognostic Signature Based on the Copy Number Variation (CNV) and Expression in Acute Myeloid Leukemia

Author

Niu, Changchun, primary, Wu, Di, additional, Li, Alexander J., additional, Qin, Kevin H., additional, Hu, Daniel A., additional, Wang, Eric J., additional, Tucker, Andrew Blake, additional, He, Fang, additional, Huang, Linjuan, additional, Wang, Hao, additional, Liu, Qing, additional, Ni, Na, additional, Shi, Deyao, additional, Zhao, Xia, additional, Wan, Yafang, additional, Li, Tian, additional, He, Tong-Chuan, additional, and Liao, Pu, additional

Published
2020
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144. A framework for aquatic invasive species surveillance site selection and prioritization in the US waters of the Laurentian Great Lakes

Author

Tucker, Andrew, primary, Chadderton, Lindsay, additional, Annis, Gust, additional, Davidson, Alisha, additional, Hoffman, Joel, additional, Bossenbroek, Jon, additional, Hensler, Stephen, additional, Hoff, Michael, additional, Jensen, Erika, additional, Kashian, Donna, additional, LeSage, Sarah, additional, and Strakosh, Timothy, additional

Published
2020
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