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305 results on '"Tonietti G"'

101. Lymphocyte activation and interleukin-2 production in nifedipinetreated subjects

Author

Famularo, G., Giacomelli, R., Luciani, A, Sacchetti, S., Radicioni, Antonio, and Tonietti, G.

Subjects
mitogen stimulation, nifedipine, immunosuppression, Interleukin-2, calcium-channel blocker, immunosuppression, Interleukin-2, lymphocyte activation, mitogen stimulation, nifedipine, calcium-channel blocker, lymphocyte activation
Published
1990

103. Ciclosporin (CyA) and H2-Receptor Antagonists

Author

Filingeri, V, Rosati, R, Stortoni, F, Iacona, A, Giacomelli, R, Famularo, G, Calogero, A, Cervelli, V, Tonietti, G, and Casciani, Cu

Subjects
Settore MED/18 - Chirurgia Generale
Published
1990

116. γ/δ T Cells are not Involved in the Natural and Antibody-Dependent Cytotoxicity of Peripheral blood Mononuclear Cells in Inflammatory Bowel Disease

Author

Giacomelli, R., primary, Passacantando, A., additional, Parzanese, I., additional, Cucinelli, F., additional, Klidara, N., additional, Lattanzio, R., additional, Santori, E., additional, Paolini, F., additional, Manetti, L.L., additional, D'Alo, S., additional, Cipriani, P., additional, Cifone, M.G., additional, and Tonietti, G., additional

Published
1997
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120. Clinical Results of a Multicenter Study with Sulbactam/Ampicillin for the Treatment of Patients with Lower Respiratory and Urinary Tract Infections

Author

De Simone, C., primary, Chiodo, F., additional, Delia, S., additional, Pastore, G., additional, Scalise, G., additional, Sorice, F., additional, Tonietti, G., additional, Zanussi, C., additional, Paoloni, M., additional, Gargiulo, M., additional, Lambert Gardini, S., additional, Giacometti, A., additional, Tzantzoglou, S., additional, Trinchieri, V., additional, and D’Annibali, E., additional

Published
1991
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122. Natural killer activity and antibody-dependent cellular cytotoxicity in progressive systemic sclerosis.

Author

Cifone, M. Grazia, Giacomelli, R., Famularo, G., Paolini, R., Danese, C., Napolitano, T., Procopio, A., Perego, A. M., Santoni, A., and Tonietti, G.

Subjects
KILLER cells, CELLS, LYMPHOCYTES, LEUKOCYTES, ANTIBODY-dependent cell cytotoxicity, SYSTEMIC scleroderma
Abstract

Enhanced natural killer (NK) activity and normal lymphocyte antibody-dependent cellular cytotoxicity (ADCC) were observed in 16 patients with a diagnosis of progressive systemic sclerosis (PSS). Higher NK activity levels were observed against NK-sensitive K562 target cells. while the NK- resistant P815. Daudi and Raji cell lines were not lysed. Cytofluorimetric studies and morphological analysis of peripheral blood lymphocytes (PBL) showed an increased number of CDI6 positive cells and large granular lymphocytes (LGL)1 indicating that the enhancement observed was probably attributable to an increase in the number of circulating NK cells. [ABSTRACT FROM AUTHOR]

Published
1990

124. HNK-1 monoclonal antibody (Leu-7) in the identification of abnormal expansions of large granular lymphocytes.

Author

Pandolfi, F., Semenzato, G., de Rossi, G., Quinti, Isabella, Guglielmi, C., Pezzutto, A., Lopez, Mauela, Tonietti, G., Fontana, L., Abo, T., and Aiuti, F.

Subjects
MONOCLONAL antibodies, LEUKOCYTES, T cells, ANTIGENS, CELL proliferation, IMMUNITY
Abstract

Among 12 cases of chronic T lymphoproliferative disorders we observed, six patients showed an expansion of mononuclear cells with azurophilic granules usually referred to as large granular lymphocytes or LGL. Cells obtained from five patients with these abnormal LGL proliferations were studied with several surface markers including their reactivity with the HNK-1 monoclonal antibody reported to be specific for LGL. Ceils in four out of five cases were HNK-t positive. Whereas normal LGL have been reported to be unreactive with several T cell markers, three cases showed the co-existence of HNK-1 and surface markers expressed by T cells. Two cases were characterized by the proliferation of OKT8 cells. Cells from one patient were HNK-l positive but did not express T or monocytic antigens. These cells were apparently not completely mature since 2-naphthyl acetate acid esterase activity was negative. Cells from the remaining case were HNK-1 negative and positive for T and monocytic antigens. An increase of OKT-10 cells was observed in only one patient. Our data indicate that proliferations of LGL represent a remarkable proportion of the rare cases of sheep erythrocyte rosetting chronic lymphocytic leukaemias or lymphomas. Besides the morphology of LGL, the rosetting ability and the negativity for peroxidase, cells from these cases showed a vast heterogeneity of other structural and functional markers, possibly reflecting different stages in the maturation of these cells. The HNK-1 monoclonal antibody proved to bean important marker in the identification of these cases. [ABSTRACT FROM AUTHOR]

Published
1983

125. Cyclophosphamide pulse regimen in the treatment of alveolitis in systemic sclerosis

Author

Roberto Giacomelli, Valentini, G., Salsano, F., Cipriani, P., Sambo, P., Conforti, M. L., Fulminis, A., Luca, A., Farina, G., Candela, M., Generini, S., Francisci, A., Tirri, E., Proietti, M., Bombardieri, S., Gabrielli, A., Tonietti, G., Cerinic, M. M., Giacomelli, R, Valentini, Gabriele, Salsano, F, Cipriani, P, Sambo, P, Conforti, Ml, Fulminis, A, DE LUCA, A, Farina, G, Candela, M, Generini, S, DE FRANCISCI, A, Tirri, E, Proietti, M, Bombardieri, S, Gabrielli, A, Tonietti, G, and Cerinic, Mm

Subjects
pulmonary fibrosis, systemic sclerosis, cyclophosphamide, alveolitis

128. [The immunity of senescence. Study of lymphocytes in vitro. I: Rosette forming lymphocytes]

Author

Ma, Perego, Tonietti G, Ranucci A, Cristina RINALDI, and Del Gobbo V

Subjects
Male, Aging, B-Lymphocytes, Rosette Formation, T-Lymphocytes, Humans, Female, Lymphocytes, Middle Aged, Aged
Abstract

E and EAC rosettes forming lymphocytes were evaluated in 25 elderly subjects (mean age 84.76 years) without manifestations of neoplastic or infectious diseases. The percentage of E rosettes appeared within the normal range in about 50 per cent of cases and below normal in remaining 50 per cent. No evident sex-related differences were observed. The percentage of EAC rosettes showed a larger distribution of values. In fact, 56 per cent of cases fell within normal limits, 26 per cent was higher and 20 per cent lower than normal. Our results are in agreement with the data reported in the most recent literature, which indicates that the main target of immune system senescence is the T-cell population, while B cells do not show significant age-related variations. The significant number of cases with percentages of EAC rosettes higher than normal may be attributed to the failure of immune homeostatic mechanisms normally exerted by T cell subpopulations. Further studies on several immune system functions in advanced age are in progress.

Published
1981

135. Ciclosporin (CyA) and H2-Receptor Antagonists

Author

Filingeri, V, Giacomelli, R, Famularo, G, Rosati, R, Calogero, A, Nardi, S, Iacona, A, Stortoni, F, Sacchetti, S, Cervelli, V, Tonietti, G, and Casciani, Cu

Subjects
Settore MED/18 - Chirurgia Generale
Published
1988

147. Ciclosporina ed H2-antagonisti

Author

Filingeri, V, Rosati, R, Stortoni, F, Iacona, A, Giacomelli, R, Famularo, G, Calogero, A, Cervelli, V, Tonietti, G, and Casciani, Cu

Subjects
Settore MED/18 - Chirurgia Generale
Published
1987

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