101. Fractional Exhaled Nitric Oxide Nonsuppression Identifies Corticosteroid-Resistant Type 2 Signaling in Severe Asthma.
- Author
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Couillard, Simon, Shrimanker, Rahul, Chaudhuri, Rekha, Mansur, Adel H., McGarvey, Lorcan P., Heaney, Liam G., Fowler, Stephen J., Bradding, Peter, Pavord, Ian D., Hinks, Timothy S. C., and MRC UK Refractory Asthma Stratification programme (RASP-UK)
- Subjects
NITRIC oxide ,EOSINOPHILS ,SPUTUM ,INFLAMMATION ,ASTHMA ,DRUG therapy for asthma ,ASTHMA diagnosis ,RESEARCH ,ADRENOCORTICAL hormones ,CROSS-sectional method ,RESEARCH methodology ,DRUG resistance ,CASE-control method ,MEDICAL cooperation ,EVALUATION research ,BRONCHODILATOR agents ,SEVERITY of illness index ,COMPARATIVE studies ,RESEARCH funding ,BREATH tests ,INHALATION administration ,RESPIRATION - Abstract
The article presents a study on the association of fractional exhaled nitric oxide and blood eosinophils with inflammation observed in the sputum and blood compartments in severe asthma. Topics discussed include the prognostic information on the occurrence of severe asthma attacks being provided by fractional exhaled nitric oxide and the blood eosinophil, the methods used in the study, and limitations of the study.
- Published
- 2021
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