101. Cerebral Erdheim-Chester disease: persistent enhancement with Gd-DTPA on MR images.
- Author
-
Tien RD, Brasch RC, Jackson DE, and Dillon WP
- Subjects
- Brain pathology, Contrast Media, Gadolinium, Gadolinium DTPA, Histiocytes pathology, Humans, Male, Middle Aged, Time Factors, Brain Diseases diagnosis, Magnetic Resonance Imaging, Organometallic Compounds, Pentetic Acid, Xanthomatosis diagnosis
- Abstract
A case of Erdheim-Chester disease with intracerebral masses containing characteristic lipid-laden histiocytes is presented. These unusual lesions remained enhanced on magnetic resonance images obtained 8 days after injection of gadolinium diethylenetriaminepentaacetic acid (DTPA) dimeglumine. Chemical analysis of a biopsy specimen revealed a high concentration of gadolinium. Findings suggest that the Gd-DTPA complex or possibly a gadolinium-containing metabolite may be retained for extended periods in this unusual type of histiocytic lesion.
- Published
- 1989
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