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1,350 results on '"Thomas, Pascal"'

101. Multidisciplinary Tumor Board Decision Making for Postoperative Radiotherapy in Thymic Epithelial Tumors: Insights from the RYTHMIC Prospective Cohort

Author

Basse, Clémence, Thureau, Sébastien, Bota, Suzanna, Dansin, Eric, Thomas, Pascal-Alexandre, Pichon, Eric, Lena, Hervé, Massabeau, Carole, Clément-Duchene, Christelle, Massard, Gilbert, Westeel, Virginie, Quantin, Xavier, Oulkhouir, Youssef, Danhier, Serge, Lerouge, Delphine, Tanguy, Ronan, Thillays, François, Le Pechoux, Cécile, Dubray, Bernard, Thiberville, Luc, Besse, Benjamin, and Girard, Nicolas

Published
2017
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104. Finite interpolation with minimum uniform norm in C^n

Author

Amar, Eric and Thomas, Pascal J.

Subjects
Mathematics - Complex Variables, 32
Abstract

Given a finite sequence $a:={a_1, ..., a_N}$ in a domain $\Omega \subset C^n$, and complex scalars $v:={v_1, ..., v_N}$, consider the classical extremal problem of finding the smallest uniform norm of a holomorphic function verifying $f(a_j)=v_j$ for all $j$. We show that the modulus of the solutions to this problem must approach its least upper bound along a subset of the boundary of the domain large enough to contain the support of a measure whose hull contains a subset of the original $a$ large enough to force the same minimum norm. Furthermore, all the solutions must agree on a variety which also contains this hull. An example is given to show that the inclusions can be strict.

Published
1997

105. Local and global visibility and Gromov hyperbolicity of domains with respect to the Kobayashi distance.

Author

Bracci, Filippo, Gaussier, Hervé, Nikolov, Nikolai, and Thomas, Pascal J.

Subjects
HYPERBOLIC spaces, HOLOMORPHIC functions, VISIBILITY
Abstract

We introduce the notion of locally visible and locally Gromov hyperbolic domains in \mathbb {C}^d. We prove that a bounded domain in \mathbb {C}^d is locally visible and locally Gromov hyperbolic if and only if it is (globally) visible and Gromov hyperbolic with respect to the Kobayashi distance. This allows to detect, from local information near the boundary, those domains which are Gromov hyperbolic and for which biholomorphisms extend continuously up to the boundary. [ABSTRACT FROM AUTHOR]

Published
2024
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106. Sampling sets for Hardy spaces of the disk

Author

Thomas, Pascal J.

Subjects
Mathematics - Complex Variables, 32
Abstract

We propose two possible definitions for the notion of a sampling sequence (or set) for Hardy spaces of the disk. The first one is inspired by recent work of Bruna, Nicolau, and \O yma about interpolating sequences in the same spaces, and it yields sampling sets which do not depend on the value of $p$ and correspond to the result proved for bounded functions ($p=\infty$) by Brown, Shields and Zeller. The second notion, while formally closer to the one used for weighted Bergman spaces, is shown to lead to trivial situations only, but raises a possibly interesting problem.

Published
1996

107. Effectiveness of Surgeon-Performed Paravertebral Block Analgesia for Minimally Invasive Thoracic Surgery: A Randomized Clinical Trial.

Author

Chenesseau, Josephine, Fourdrain, Alex, Pastene, Bruno, Charvet, Aude, Rivory, Adrien, Baumstarck, Karine, Bouabdallah, Ilies, Trousse, Delphine, Boulate, David, Brioude, Geoffrey, Gust, Lucile, Vasse, Matthieu, Braggio, Cesare, Mora, Pierre, Labarriere, Ambroise, Zieleskiewicz, Laurent, Leone, Marc, Thomas, Pascal Alexandre, and D'Journo, Xavier-Benoit

Published
2023
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109. Interpolating sequences for weighted Bergman spaces of the ball

Author

Jevtić, Miroljub, Massaneda, Xavier, and Thomas, Pascal J.

Subjects
Mathematics - Complex Variables, 32
Abstract

Let $B_{\alpha}^{p}$ be the space of $f$ holomorphic in the unit ball of $\Bbb C^n$ such that $(1-|z|^2)^\alpha f(z) \in L^p$, where $0

Published
1995

111. Oropharyngeal and nasopharyngeal decontamination with chlorhexidine gluconate in lung cancer surgery: a randomized clinical trial

Author

D’Journo, Xavier Benoit, Falcoz, Pierre-Emmanuel, Alifano, Marco, Le Rochais, Jean-Philippe, D’Annoville, Thomas, Massard, Gilbert, Regnard, Jean Francois, Icard, Philippe, Marty-Ane, Charles, Trousse, Delphine, Doddoli, Christophe, Orsini, Bastien, Edouard, Sophie, Million, Matthieu, Lesavre, Nathalie, Loundou, Anderson, Baumstarck, Karine, Peyron, Florence, Honoré, Stephane, Dizier, Stéphanie, Charvet, Aude, Leone, Marc, Raoult, Didier, Papazian, Laurent, and Thomas, Pascal Alexandre

Published
2018
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112. Prediction of survival after lung transplantation at one year (SALTO cohort) using information available at different key time-points

Author

Belaroussi, Yaniss, primary, Hustache-Castaing, Romain, additional, Maury, Jean-Michel, additional, Lehot, Laurent, additional, Rodriguez, Arnaud, additional, Demant, Xavier, additional, Rozé, Hadrien, additional, Brioude, Geoffrey, additional, D’Journo, Xavier-Benoit, additional, Drevet, Gabrielle, additional, Tronc, Francois, additional, Mathoulin-Pélissier, Simone, additional, Jougon, Jacques, additional, Thomas, Pascal-Alexandre, additional, and Thumerel, Matthieu, additional

Published
2023
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115. Prognostic score and sex-specific nomograms to predict survival in resectable lung cancer: a French nationwide study from the Epithor cohort database

Author

Alifano, Marco, primary, Daffré, Elisa, additional, Brouchet, Laurent, additional, Falcoz, Pierre Emmanuel, additional, Le Pimpec Barthes, Françoise, additional, Pages, Pierre Benoit, additional, Thomas, Pascal Alexandre, additional, Dahan, Marcel, additional, and Porcher, Raphael, additional

Published
2023
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116. Risk Prediction Model of 90-Day Mortality after Esophagectomy for Cancer

Author

D'Journo, Xavier Benoit, Boulate, David, Fourdrain, Alex, Loundou, Anderson, van Berge Henegouwen, Mark I, Gisbertz, Suzanne S, O'Neill, J Robert, Hoelscher, Arnulf, Piessen, Guillaume, van Lanschot, Jan, Wijnhoven, Bas, Jobe, Blair, Davies, Andrew, Schneider, Paul M, Pera, Manuel, Nilsson, Magnus, Nafteux, Philippe, Kitagawa, Yuko, Morse, Christopher R, Hofstetter, Wayne, Molena, Daniela, Jimmy Bok-Yan, So, Immanuel, Arul, Parsons, Simon L, Larsen, Michael Hareskov, Dolan, James P, Wood, Stephanie G, Maynard, Nick, Smithers, Mark, Puig, Sonia, Law, Simon, Wong, Ian, Kennedy, Andrew, Kangning, Wang, Reynolds, John V, Pramesh, C S, Ferguson, Mark, Darling, Gail, Schröder, Wolfgang, Bludau, Marc, Underwood, Tim, van Hillegersberg, Richard, Chang, Andrew, Cecconello, Ivan, Ribeiro, Ulysses, de Manzoni, Giovanni, Rosati, Riccardo, Kuppusamy, Madhankumar, Thomas, Pascal Alexandre, Low, Donald E, Weindelmayer, J., Surgery, CCA - Cancer Treatment and Quality of Life, AGEM - Amsterdam Gastroenterology Endocrinology Metabolism, D'Journo, Xavier Benoit, Boulate, David, Fourdrain, Alex, Loundou, Anderson, van Berge Henegouwen, Mark I, Gisbertz, Suzanne S, O'Neill, J Robert, Hoelscher, Arnulf, Piessen, Guillaume, van Lanschot, Jan, Wijnhoven, Ba, Jobe, Blair, Davies, Andrew, Schneider, Paul M, Pera, Manuel, Nilsson, Magnu, Nafteux, Philippe, Kitagawa, Yuko, Morse, Christopher R, Hofstetter, Wayne, Molena, Daniela, So, Jimmy Bok-Yan, Immanuel, Arul, Parsons, Simon L, Larsen, Michael Hareskov, Dolan, James P, Wood, Stephanie G, Maynard, Nick, Smithers, Mark, Puig, Sonia, Law, Simon, Wong, Ian, Kennedy, Andrew, Kangning, Wang, Reynolds, John V, Pramesh, C S, Ferguson, Mark, Darling, Gail, Schröder, Wolfgang, Bludau, Marc, Underwood, Tim, van Hillegersberg, Richard, Chang, Andrew, Cecconello, Ivan, Ribeiro, Ulysse, de Manzoni, Giovanni, Rosati, Riccardo, Kuppusamy, Madhankumar, Thomas, Pascal Alexandre, and Low, Donald E

Subjects
Male, medicine.medical_specialty, Time Factors, Esophageal Neoplasms, medicine.medical_treatment, 030230 surgery, Logistic regression, Risk Assessment, 03 medical and health sciences, 0302 clinical medicine, Postoperative Complications, SDG 3 - Good Health and Well-being, Risk Factors, Internal medicine, medicine, Humans, Retrospective Studies, Original Investigation, Models, Statistical, Performance status, Receiver operating characteristic, business.industry, Mortality rate, Esophageal cancer, Middle Aged, medicine.disease, Prognosis, Esophagectomy, 030220 oncology & carcinogenesis, Cohort, Surgery, Female, business, Body mass index
Abstract

Importance: Ninety-day mortality rates after esophagectomy are an indicator of the quality of surgical oncologic management. Accurate risk prediction based on large data sets may aid patients and surgeons in making informed decisions. Objective: To develop and validate a risk prediction model of death within 90 days after esophagectomy for cancer using the International Esodata Study Group (IESG) database, the largest existing prospective, multicenter cohort reporting standardized postoperative outcomes. Design, Setting, and Participants: In this diagnostic/prognostic study, we performed a retrospective analysis of patients from 39 institutions in 19 countries between January 1, 2015, and December 31, 2019. Patients with esophageal cancer were randomly assigned to development and validation cohorts. A scoring system that predicted death within 90 days based on logistic regression ß coefficients was conducted. A final prognostic score was determined and categorized into homogeneous risk groups that predicted death within 90 days. Calibration and discrimination tests were assessed between cohorts. Exposures: Esophageal resection for cancer of the esophagus and gastroesophageal junction. Main Outcomes and Measures: All-cause postoperative 90-day mortality. Results: A total of 8403 patients (mean [SD] age, 63.6 [9.0] years; 6641 [79.0%] male) were included. The 30-day mortality rate was 2.0% (n = 164), and the 90-day mortality rate was 4.2% (n = 353). Development (n = 4172) and validation (n = 4231) cohorts were randomly assigned. The multiple logistic regression model identified 10 weighted point variables factored into the prognostic score: age, sex, body mass index, performance status, myocardial infarction, connective tissue disease, peripheral vascular disease, liver disease, neoadjuvant treatment, and hospital volume. The prognostic scores were categorized into 5 risk groups: very low risk (score, =1; 90-day mortality, 1.8%), low risk (score, 0; 90-day mortality, 3.0%), medium risk (score, -1 to -2; 90-day mortality, 5.8%), high risk (score, -3 to -4: 90-day mortality, 8.9%), and very high risk (score, =-5; 90-day mortality, 18.2%). The model was supported by nonsignificance in the Hosmer-Lemeshow test. The discrimination (area under the receiver operating characteristic curve) was 0.68 (95% CI, 0.64-0.72) in the development cohort and 0.64 (95% CI, 0.60-0.69) in the validation cohort. Conclusions and Relevance: In this study, on the basis of preoperative variables, the IESG risk prediction model allowed stratification of an individual patient's risk of death within 90 days after esophagectomy. These data suggest that this model can help in the decision-making process when esophageal cancer surgery is being considered and in informed consent.

Published
2021

121. Is the Epithor conversion score reliable in robotic-assisted surgery anatomical lung resection?

Author

Armand, Elsa, Fourdrain, Alex, Lafouasse, Chloé, Resseguier, Noémie, Trousse, Delphine, D'Journo, Xavier-Benoît, and Thomas, Pascal-Alexandre

Subjects
LUNG surgery, VIDEO-assisted thoracic surgery, MINIMALLY invasive procedures, PERIPHERAL vascular diseases, CHEST endoscopic surgery, ANKLE brachial index
Abstract

Open in new tab Download slide OBJECTIVES Despite an improvement in surgical abilities, the need for an intraoperative switch from a minimally invasive procedure towards an open surgery (conversion) still remains. To anticipate this risk, the Epithor conversion score (ECS) has been described for video-assisted thoracoscopic surgery (VATS). Our objective was to determine if this score, developed for VATS, is applicable in robotic-assisted thoracoscopic surgery (RATS). METHODS This was a retrospective monocentric study from January 2006 to June 2022, and data were obtained from the EPITHOR database. Patients included were those who underwent anatomic lung resection either by VATS or RATS. The ECS was calculated for all patients studied. Discrimination and calibration of the test were measured by the area under the curve and Hosmer–Lemeshow test. RESULTS A total of 1685 were included. There were 183/1299 conversions in the VATS group (14.1%) and 27/386 conversions in the RATS group (6.9%). Patients in the RATS group had fewer antiplatelet therapy and peripheral arterial disease. There were more segmentectomies in the VATS group. As for test discrimination, the area under the curve was 0.66 [0.56–0.78] in the RATS group and 0.64 [0.60–0.69] in the VATS group. Regarding the calibration, the Hosmer–Lemeshow test was not significant for both groups but more positive (better calibrated) for the VATS group (P  = 0.12) compared to the RATS group (P  = 0.08). CONCLUSIONS The ECS seems applicable for patients operated with RATS, with a correct discrimination but a lower calibration performance for patients operated with VATS. A new score could be developed to specifically anticipate conversion in patients operated on by RATS. [ABSTRACT FROM AUTHOR]

Published
2023
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122. Lung Transplantation for Primary Ciliary Dyskinesia and Kartagener Syndrome: A Multicenter Study

Author

Marro, Matteo, primary, Leiva-Juárez, Miguel M., additional, D’Ovidio, Frank, additional, Chan, Justin, additional, Van Raemdonck, Dirk, additional, Ceulemans, Laurens Joseph, additional, Moreno, Paula, additional, Kindelan, Antonio Alvarez, additional, Krueger, Thorsten, additional, Koutsokera, Angela, additional, Ehrsam, Jonas Peter, additional, Inci, Ilhan, additional, Yazicioglu, Alkin, additional, Yekeler, Erdal, additional, Boffini, Massimo, additional, Brioude, Geoffrey, additional, Thomas, Pascal Alexandre, additional, Pizanis, Nikolaus, additional, Aigner, Clemens, additional, Schiavon, Marco, additional, Rea, Federico, additional, Anile, Marco, additional, Venuta, Federico, additional, and Keshavjee, Shaf, additional

Published
2023
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127. Benignant and malignant epidemiology among surgical resections for suspicious solitary lung cancer without preoperative tissue diagnosis

Author

Armand, Elsa, primary, Boulate, David, additional, Fourdrain, Alex, additional, Nguyen, Ngoc-Anh-Thu, additional, Resseguier, Noémie, additional, Brioude, Geoffrey, additional, Trousse, Delphine, additional, Doddoli, Christophe, additional, D’journo, Xavier-Benoit, additional, and Thomas, Pascal-Alexandre, additional

Published
2022
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128. Lung Transplantation for Primary Ciliary Dyskinesia and Kartagener Syndrome : A Multicenter Study

Author

Marro, Matteo, Leiva-Juárez, Miguel M., D'Ovidio, Frank, Chan, Justin, Van Raemdonck, Dirk, Ceulemans, Laurens Joseph, Moreno, Paula, Kindelan, Antonio Alvarez, Krueger, Thorsten, Koutsokera, Angela, Ehrsam, Jonas Peter, Inci, Ilhan, Yazicioglu, Alkin, Yekeler, Erdal, Boffini, Massimo, Brioude, Geoffrey, Thomas, Pascal Alexandre, Pizanis, Nikolaus, Aigner, Clemens, Schiavon, Marco, Rea, Federico, Anile, Marco, Venuta, Federico, Keshavjee, Shaf, and D’Ovidio, Frank

Subjects
Transplantation, Kartagener Syndrome, Biopsy, Data Collection, primary graft dysfunction, Medizin, rare disease, Humans, outcomes, lung transplant, chronic lung allograft dysfunction, Retrospective Studies, Lung Transplantation
Abstract

Primary ciliary dyskinesia, with or without situs abnormalities, is a rare lung disease that can lead to an irreversible lung damage that may progress to respiratory failure. Lung transplant can be considered in end-stage disease. This study describes the outcomes of the largest lung transplant population for PCD and for PCD with situs abnormalities, also identified as Kartagener's syndrome. Retrospectively collected data of 36 patients who underwent lung transplantation for PCD from 1995 to 2020 with or without SA as part of the European Society of Thoracic Surgeons Lung Transplantation Working Group on rare diseases. Primary outcomes of interest included survival and freedom from chronic lung allograft dysfunction. Secondary outcomes included primary graft dysfunction within 72 h and the rate of rejection ≥A2 within the first year. Among PCD recipients with and without SA, the mean overall and CLAD-free survival were 5.9 and 5.2 years with no significant differences between groups in terms of time to CLAD (HR: 0.92, 95% CI: 0.27-3.14, p = 0.894) or mortality (HR: 0.45, 95% CI: 0.14-1.43, p = 0.178). Postoperative rates of PGD were comparable between groups; rejection grades ≥A2 on first biopsy or within the first year was more common in patients with SA. This study provides a valuable insight on international practices of lung transplantation in patients with PCD. Lung transplantation is an acceptable treatment option in this population. ispartof: TRANSPLANT INTERNATIONAL vol:36 ispartof: location:Switzerland status: published

Published
2023

131. Robotic vs Thoracoscopic Anatomic Lung Resection in Obese Patients: A Propensity-Adjusted Analysis

Author

Seder, Christopher W., primary, Farrokhyar, Forough, additional, Nayak, Rahul, additional, Baste, Jean-Marc, additional, Patel, Yogita, additional, Agzarian, John, additional, Finley, Christian J., additional, Shargall, Yaron, additional, Thomas, Pascal-Alexandre, additional, Dahan, Marcel, additional, Verhoye, Jean-Philippe, additional, Mbadinga, Frankie, additional, and Hanna, Waël C., additional

Published
2022
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132. Impact of the implementation of a trauma system on compliance with evidence-based clinical management guidelines in penetrating thoracic trauma

Author

Vasse, Matthieu, primary, Leone, Marc, additional, Boyer, Laurent, additional, Michelet, Pierre, additional, Goudard, Yvain, additional, Cardinale, Michael, additional, Paris, Raphael, additional, Avaro, Jean Philippe, additional, Thomas, Pascal Alexandre, additional, and de Lesquen, Henri, additional

Published
2022
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135. Multicentric evaluation of the impact of central tumour location when comparing rates of N1 upstaging in patients undergoing video-assisted and open surgery for clinical Stage I non-small-cell lung cancer†

Author

Decaluwé, Herbert, Petersen, René Horsleben, Brunelli, Alex, Pompili, Cecilia, Seguin-Givelet, Agathe, Gust, Lucile, Aigner, Clemens, Falcoz, Pierre-Emmanuel, Rinieri, Philippe, Augustin, Florian, Sokolow, Youri, Verhagen, Ad, Depypere, Lieven, Papagiannopoulos, Kostas, Gossot, Dominique, D’Journo, Xavier Benoit, Guerrera, Francesco, Baste, Jean-Marc, Schmid, Thomas, Stanzi, Alessia, Van Raemdonck, Dirk, Bardet, Jeremy, Thomas, Pascal-Alexandre, Massard, Gilbert, Fieuws, Steffen, Moons, Johnny, Dooms, Christophe, De Leyn, Paul, and Hansen, Henrik Jessen

Published
2018
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136. Associations between the severity of medical and surgical complications and perception of surgeon empathy in esophageal and gastric cancer patients

Author

Gehenne, Lucie, Lelorain, Sophie, Eveno, Clarisse, Piessen, Guillaume, Mariette, Christophe, Glehen, Olivier, d'Journo, Xavier, Mathonnet, Muriel, Regenet, Nicolas, Meunier, Bernard, Baudry, Anne-Sophie, Christophe, Véronique, Adenis, Antoine, Aparicio, Thomas, Assenat, Eric, Barret, Maximilien, Benhaim, Leonor, Benoit, Céline, Bergeat, Damien, Boige, Valérie, Borie, Fréderic, Bouche, Olivier, Bourriez, Damien, Brichon, Pierre-Yves, Brigand, Cécile, Carrere, Nicolas, Cattan, Pierre, Christou, Niki, Coffin, Benoit, Cohen, Romain, Collet, Denis, Conroy, Thierry, Dahan, Laetitia, Deguelte, Sophie, Di Fiore, Fréderic, Dousset, Bertrand, Drouillard, Antoine, Dumont, Frédéric, Elhajbi, Farid, Fabre, Jean Michel, Fabre, Joseph, Gagniere, Johan, Galais, Marie Pierre, Germain, Adeline, Geyl, Sophie, Goere, Diane, Gornet, Jean Marc, Granger, Victoire, Gronnier, Caroline, Guimbaud, Rosine, Hautefeuille, Vincent, Helyon, Morgane, Jougon, Jacques, Lebreton, Gilles, Lefevre, Jérémie, Lepage, Côme, Lievre, Astrid, Marchal, Frédéric, Mathieu, Pierre, Mathysiak, Tamara, Michot, Nicolas, Moszkowicz, David, Moussata, Driffa, Msika, Simon, Neuzillet, Cindy, Ouaissi, Medhi, Paquette, Brice, Paye, François, Penna, Christophe, Père, Guillaume, Perrier, Marine, Peschaud, Frédérique, Pezet, Denis, Phoutthsang, Valérie, Pocard, Marc, Rat, Paul, Regimbeau, Jean Marc, Renaud, Florence, Sabate, Jean-Marc, Souche, Régis, Terrebonne, Eric, Tessier, Williams, Thomas, Pascal Alexandre, Turpin, Anthony, Vaudoyer, Delphine, Vienot, Angélique, Voron, Thibault, You, Benoit, Laboratoire Sciences Cognitives et Sciences Affectives - UMR 9193 (SCALab), Université de Lille-Centre National de la Recherche Scientifique (CNRS), Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), Cancer Heterogeneity, Plasticity and Resistance to Therapies - UMR 9020 - U 1277 (CANTHER), Institut Pasteur de Lille, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille)-Centre National de la Recherche Scientifique (CNRS), Centre Hospitalier Lyon Sud [CHU - HCL] (CHLS), Hospices Civils de Lyon (HCL), Centre de Recherche en Cancérologie de Marseille (CRCM), Aix Marseille Université (AMU)-Institut Paoli-Calmettes, Fédération nationale des Centres de lutte contre le Cancer (FNCLCC)-Fédération nationale des Centres de lutte contre le Cancer (FNCLCC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Service de Chirurgie digestive, endocrinienne et générale [CHU Limoges], CHU Limoges, Centre hospitalier universitaire de Nantes (CHU Nantes), CHU Pontchaillou [Rennes], Centre hospitalier [Valenciennes, Nord], Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier), Institut de Génétique Moléculaire de Montpellier (IGMM), and Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS)

Subjects
medicine.medical_specialty, Esophageal Neoplasms, media_common.quotation_subject, education, [SDV.CAN]Life Sciences [q-bio]/Cancer, Empathy, MESH: Perception, Odds, Postoperative complications, MESH: Surgeons, 03 medical and health sciences, 0302 clinical medicine, Stomach Neoplasms, Perception, Internal medicine, Humans, Medicine, 030212 general & internal medicine, Major complication, Retrospective Studies, Cancer, media_common, Multinomial logistic regression, Surgeons, Physician-Patient Relations, MESH: Humans, business.industry, Nursing research, MESH: Retrospective Studies, Cognition, MESH: Stomach Neoplasms, medicine.disease, Patient-physician communication, MESH: Empathy, Oncology, 030220 oncology & carcinogenesis, MESH: Esophageal Neoplasms, MESH: Physician-Patient Relations, business, [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology
Abstract

International audience; Objective: To assess the impact of global physician empathy and its three subdimensions (establishing rapport, emotional and cognitive processes) on the severity of postoperative complications in a sample of cancer patients.Methods: We retrospectively analyzed data on 256 patients with esogastric cancer from the French national FREGAT database. Empathy and its subdimensions were assessed using the patient-reported CARE scale and the severity of medical and surgical complications was reported with the Clavien-Dindo classification system. The usual covariates were included in multinomial logistic regression analyses.Results: Physician empathy predicted the odds of reporting major complications. When patients perceived high empathy, they were less likely to report major complications compared to no complications (OR = .95, 95% CI = [.91-.99], p = .029). Among the three dimensions, only "establishing rapport" (OR = .84, 95% CI = [.73-.98], p = .019) and the "emotional process" (OR = .85, 95% CI = [.74-.98], p = .022) predicted major complications.Conclusions: Physician empathy is essential before surgery. Further research is needed to understand the mechanisms associating empathy with health outcomes in cancer. Physicians should be trained to establish good rapport with patients, especially in the preoperative period.

Published
2021

138. Management of lung transplantation in the COVID-19 era-An international survey

Author

Coiffard, Benjamin, Lepper, Philipp M., Prud'Homme, Eloi, Daviet, Florence, Cassir, Nadim, Wilkens, Heinrike, Hraiech, Sami, Langer, Frank, Thomas, Pascal A., Reynaud-Gaubert, Martine, Bals, Robert, Schäfers, Hans-Joachim, Papazian, Laurent, and Seiler, Frederik

Subjects
immunosuppressive regimens, infection and infectious agents - viral, immunosuppression / immune modulation, infectious disease, clinical research / practice, waitlist management, antibiotic: antiviral, recipient selection, lung transplantation / pulmonology
Published
2022
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140. Mobilisation of HLA‐F on the surface of bronchial epithelial cells and platelets in asthmatic patients

Author

Fiouane, Sabrina, primary, Chebbo, Mohamad, additional, Beley, Sophie, additional, Paganini, Julien, additional, Picard, Christophe, additional, D'Journo, Xavier‐Benoît, additional, Thomas, Pascal‐Alexandre, additional, Chiaroni, Jacques, additional, Chanez, Pascal, additional, Gras, Delphine, additional, and Di Cristofaro, Julie, additional

Published
2022
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141. Thoracic surgery in France

Author

Gossot, Dominique, primary, Saiydoun, Gabriel, additional, Leclerc, Jean-Baptiste, additional, Dahan, Marcel, additional, Thomas, Pascal Alexandre, additional, Verhoye, Jean-Philippe, additional, and Seguin-Givelet, Agathe, additional

Published
2022
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145. Does Myasthenia Gravis Affect Long-Term Survival in Thymic Carcinomas? An ESTS Database Analysis

Author

Lococo, Filippo, Nachira, Dania, Chiappetta, Marco, Evangelista, Jessica, Falcoz, Pierre Emmanuel, Ruffini, Enrico, Van Schil, Paul, Scarci, Marco, Furàk, Jòzsef, Sollitto, Francesco, Guerrera, Francesco, Spaggiari, Lorenzo, Aigner, Clemen, Evangelia, Liverakou, Billè, Andrea, Moser, Bernhard, Thomas, Pascal Alexandre, Liberman, Moishe, Boubia, Souheil, Campisi, Alessio, Ampollini, Luca, Toker, Alper, Enyed, Attila, Voltolini, Luca, Van Raemdonck, Dirk, Margaritora, Stefano, Ests Thymic Working Group, Null, Lococo, Filippo (ORCID:0000-0002-9383-5554), Nachira, Dania (ORCID:0000-0003-2937-9678), Margaritora, Stefano (ORCID:0000-0002-9796-760X), Lococo, Filippo, Nachira, Dania, Chiappetta, Marco, Evangelista, Jessica, Falcoz, Pierre Emmanuel, Ruffini, Enrico, Van Schil, Paul, Scarci, Marco, Furàk, Jòzsef, Sollitto, Francesco, Guerrera, Francesco, Spaggiari, Lorenzo, Aigner, Clemen, Evangelia, Liverakou, Billè, Andrea, Moser, Bernhard, Thomas, Pascal Alexandre, Liberman, Moishe, Boubia, Souheil, Campisi, Alessio, Ampollini, Luca, Toker, Alper, Enyed, Attila, Voltolini, Luca, Van Raemdonck, Dirk, Margaritora, Stefano, Ests Thymic Working Group, Null, Lococo, Filippo (ORCID:0000-0002-9383-5554), Nachira, Dania (ORCID:0000-0003-2937-9678), and Margaritora, Stefano (ORCID:0000-0002-9796-760X)

Abstract

Background: Thymic carcinoma is a rare and highly malignant tumor with a dismal prognosis, which occasionally coexists with myasthenia gravis (MG). This study aims to investigate the MG incidence on a surgical cohort of patients with thymic carcinoma and to explore its influence on long-term survival. Methods: the prospectively collected data from the ESTS database on thymic epithelial tumors were reviewed. Clinical, pathological, and survival information on thymic carcinoma were analyzed. Results: the analysis was conducted on 203 patients, with an equal gender distribution (96 males and 107 females). MG was detected in 22 (10.8%) patients, more frequently elderly (>60 years, p = 0.048) and male (p = 0.003). Induction therapy was performed in 22 (10.8%) cases. After surgery, 120 (59.1%) patients had a Masaoka stage II-III while complete resection (R0) was achieved in 158 (77.8%). Adjuvant therapy was performed in 68 cases. Mean follow-up was 60 (SD = 14) months. The 3-year, 5-year and 10-year survival rates were 79%, 75% and 63%, respectively. MG did not seem to influence long-term survival (5-year survival in non-MG-TCs 78% vs. 50% in MG-TCs, p = ns) as age < 60 years, female gender, early Masaoka stage, and postoperative radiotherapy did, conversely. Conclusions: myasthenia occurred in about 10% of thymic carcinomas and it did not seem to affect significantly the long-term prognosis in surgically treated thymic carcinoma-patients.

Published
2022

148. Prediction of survival after a lung transplant at 1 year (SALTO cohort) using information available at different key time points.

Author

Belaroussi, Yaniss, Hustache-Castaing, Romain, Maury, Jean-Michel, Lehot, Laurent, Rodriguez, Arnaud, Demant, Xavier, Rozé, Hadrien, Brioude, Geoffrey, D'Journo, Xavier-Benoit, Drevet, Gabrielle, Tronc, Francois, Mathoulin-Pélissier, Simone, Jougon, Jacques, Thomas, Pascal-Alexandre, and Thumerel, Matthieu

Subjects
LUNG transplantation, RECEIVER operating characteristic curves, KIDNEY transplantation, Q fever
Abstract

Open in new tab Download slide OBJECTIVES A lung transplant is the final treatment option for end-stage lung disease. We evaluated the individual risk of 1-year mortality at each stage of the lung transplant process. METHODS This study was a retrospective analysis of patients undergoing bilateral lung transplants between January 2014 and December 2019 in 3 French academic centres. Patients were randomly divided into development and validation cohorts. Three multivariable logistic regression models of 1-year mortality were applied (i) at recipient registration, (ii) the graft allocation and (iii) after the operation. The 1-year mortality was predicted for individual patients assigned to 3 risk groups at time points A to C. RESULTS The study population consisted of 478 patients with a mean (standard deviation) age of 49.0 (14.3) years. The 1-year mortality rate was 23.0%. There were no significant differences in patient characteristics between the development (n  =   319) and validation (n  =   159) cohorts. The models analysed recipient, donor and intraoperative variables. The discriminatory power (area under the receiver operating characteristic curve) was 0.67 (0.62–0.73), 0.70 (0.63–0.77) and 0.82 (0.77–0.88), respectively, in the development cohort and 0.74 (0.64–0.85), 0.76 (0.66–0.86) and 0.87 (0.79 – 0.95), respectively, in the validation cohort. Survival rates were significantly different among the low- (< 15%), intermediate- (15%–45%) and high-risk (> 45%) groups in both cohorts. CONCLUSIONS Risk prediction models allow estimation of the 1-year mortality risk of individual patients during the lung transplant process. These models may help caregivers identify high-risk patients at times A to C and reduce the risk at subsequent time points. [ABSTRACT FROM AUTHOR]

Published
2023
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