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This article advances the notion of “extractive humanitarianism” to designate the role played by data extraction and knowledge extraction operations in refugee governmentality. It argues that extractive operations rely on refugees’ active participation to their own governmentality—what I define as participatory confinement. The piece engages with feminist literature on unpaid labor and shows that participatory confinement implies that refugees perform unpaid labor activities, which are disguised as voluntary work. It moves on by conceptualizing participatory confinement through the lens of the invitation to governmentality. In order to develop this, the article focuses on two modes of participatory confinement: unpaid labor that asylum seekers do as “voluntary” activities and knowledge and data extraction. It concludes by questioning extractive humanitarianism in light of the subtle coercion and invisible exploitation that asylum seekers are exposed to.

This article investigates the fragmented knowledges that migrants need to deal with in order to get access to asylum, and the related effects of disorientation it generates on them. The piece argues that disorientation is as a constitutive political technology of refugee governance and develops this argument by focusing on the Greek asylum system. It starts by drawing attention to the multiple technological steps and forced digital intermediations that asylum seekers in Greece need to navigate, focusing in particular on the Cash Assistance Programme, and it shows how asylum seekers need to deal with dispersed knowledges. The article moves on by analysing how the governing through disorientation underpin the asylum legal system in Greece and how this ends up in debilitating asylum seekers and hampering them from accessing rights and humanitarian support. The final section explores how asylum seekers are racialised and treated as deceitful subjects, and argues that not only their speech but also their conduct and behaviour are assumed to be deceptive, and therefore their knowledge turns out to be pointless. It concludes by challenging claims for more transparency and more knowledge as a response to the governing through disorientation.

Una de las necesidades que se plantea a nivel mundial, es el estudio de la distribución espacial y la evolución de los asentamientos humanos, donde resultan clave las herramientas de la teledetección. A tales fines, se define huella urbana, al área urbanizada dominada por construcciones edilicias. El estudio de la evolución espacial y temporal de la huella urbana proporciona elementos que facilitan la planificación y el ordenamiento territorial, en pos de alcanzar ciudades y comunidades más inclusivas y sostenibles (ODS 11, UN, 2015). El objetivo del presente trabajo es identificar la huella urbana en la ciudad de Rosario (Santa Fe, Argentina), usando imágenes radar de los satélites COSMO-SkyMed y Radarsat-2, años 2013 y 2015. En el procesamiento se sigue el modelo raster binario con valor 1 (uno) en presencia de huella urbana y 0 (cero) en caso contrario. En la determinación se emplea una metodología basada en la coherencia interferométrica InSAR. En la verificación de uno de los resultados, se utiliza el producto del proyecto Global Urban Footprint (GUF), de la Agencia Espacial Alemana. El resultado derivado de imágenes COSMO-SkyMed (HU) presentó en algunos subsectores, una superficie de la huella urbana mayor respecto al producto GUF, y en otros el resultado opuesto. En base a la propuesta metodológica se determinó la huella urbana de la ciudad de Rosario para los años 2013 y 2015. La comparación con sitios testigos y con un producto de características similares, arrojaron los primeros indicios de la necesidad de continuar ampliando y profundizando el análisis. Fil: López, Diego Alejandro Germán. Universidad Nacional de Rosario. Facultad de Ciencias Exactas, Ingeniería y Agrimensura. Escuela de Agrimensura. Área de Sensores Remotos; Argentina Fil: Balparda, Laura Rita. Universidad Nacional de Rosario. Facultad de Ciencias Exactas, Ingeniería y Agrimensura. Escuela de Agrimensura. Área de Sensores Remotos; Argentina Fil: Tazzioli, Florencia. Universidad Nacional de Rosario. Facultad de Ciencias Exactas, Ingeniería y Agrimensura. Escuela de Agrimensura; Argentina Fil: Torralba, María Cecilia. Universidad Nacional de Rosario. Facultad de Ciencias Exactas, Ingeniería y Agrimensura. Escuela de Agrimensura; Argentina Fil: Ciattaglia, Brunela. Universidad Nacional de Rosario. Facultad de Ciencias Exactas, Ingeniería y Agrimensura. Escuela de Agrimensura; Argentina Fil: Peña, Héctor Carlos Enrique. Universidad Nacional de Rosario. Facultad de Ciencias Exactas, Ingeniería y Agrimensura. Escuela de Agrimensura; Argentina Fil: Solis, Tania. Universidad Nacional de Rosario. Facultad de Ciencias Exactas, Ingeniería y Agrimensura. Escuela de Agrimensura; Argentina Fil: Aquili, Verónica. Universidad Nacional de Rosario. Facultad de Ciencias Exactas, Ingeniería y Agrimensura. Escuela de Agrimensura; Argentina Fil: Delorenzi, Dardo Javier. Universidad Nacional de Rosario. Facultad de Ciencias Exactas, Ingeniería y Agrimensura. Escuela de Agrimensura; Argentina Fil: Vicioso, Benito Miguel. Universidad Nacional de Rosario. Facultad de Ciencias Exactas, Ingeniería y Agrimensura. Escuela de Agrimensura; Argentina

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Surgery for breast cancer has changed in the last few decades in favor of more conservative approaches, without compromising loco‐regional control and survival. Common immediate complications fol ‐lowing breast surgery are hematoma, seroma, and wound infection.1Traditionally, surgeons have implemented the use of closed‐suction drains in this setting with the aim of preventing these complications, which can cause discomfort, morbidity, increased follow‐up visits,and possible delay in the beginning of adjuvant therapies.2 On the other hand, potential benefits of performing breast procedures without using a drain have been increasingly considered.3 There is lack of modern and official guidelines on use of drains in breast sur ‐gery, with no consensus regarding their management and the appro‐priate use of antibiotics in this setting. Almost all reports agree withthe use of drains after breast procedures, especially if they are asso‐ciated with reconstruction or axillar lymph node dissection (ALND), but an extreme variability is reported regarding practice patterns.4A national survey regarding the management of drains afterbreast cancer surgery was sent by email on January 2018 to all Breast Centers (BC) registered with Senonetwork Italia. Data col ‐lected by the administrative office of Senonetwork were de‐iden‐tified and exported for statistical analysis. A Steering Committeecomposed of general surgeons and plastic surgeons was appointedto coordinate the survey, which consisted of 22 multiple choicequestions, designed to inquire about surgeons' demographics, use of drains after breast procedures with and without reconstructionand/or ALND, antibiotic use and to characterize drain managementin their clinical practice.

This article investigates how the security-humanitarian rationale that underpins migration governmentality has been restructured by and inflected in light of hygienic-sanitary borders which enforce racialised confinement in the name of both migrants' and citizens' safety from infection by Covid-19. Focusing on the politics of migration containment along EUrope's frontiers, examining in particular border reinforcements carried out by Italy, Malta and Greece, we interrogate how the pandemic has been exploited to enact deterrence through hygienic-sanitary border enforcements. These enforcements are underpinned by an ambivalent security-humanitarian narrative that crafts migrants as subjects who cannot be protected by EU member states from the pandemic if allowed inside, and, at once, as potential vehicles of contagion - ‘Corona spreaders’ - and thus as dangers on a bacterial-hygienic level. Our article demonstrates that these EUropean border measures are more than temporary responses to an unprecedented health crisis. Rather, the pandemic has been seized as an opportunity to strengthen existing deterrence measures and hamper migrants' access to asylum through biopolitical and spatial tactics that aim to restructure the border regime. While emphasising the historical trajectories and continuities underwriting these current developments, we contend that the pandemic functions as an accelerator of dynamics of migrant incarceration and containment.

Background Type of axillary surgery in breast cancer (BC) patients who convert from cN + to ycN0 after neoadjuvant chemotherapy (NAC) is still debated. The aim of the present study was to develop and validate a preoperative predictive nomogram to select those patients with a low risk of residual axillary disease after NAC, in whom axillary surgery could be minimized. Patients and methods 1950 clinically node-positive BC patients from 11 Breast Units, treated by NAC and subsequent surgery, were included from 2005 to 2020. Patients were divided in two groups: those who achieved nodal pCR vs. those with residual nodal disease after NAC. The cohort was divided into training and validation set with a geographic separation criterion. The outcome was to identify independent predictors of axillary pathologic complete response (pCR). Results Independent predictive factors associated to nodal pCR were axillary clinical complete response (cCR) after NAC (OR 3.11, p 14% (OR 0.52, p = 0.0005), and tumor grading G2 (OR 0.35, p = 0.002) or G3 (OR 0.29, p = 0.0003). The nomogram showed a sensitivity of 71% and a specificity of 73% (AUC 0.77, 95%CI 0.75–0.80). After external validation the accuracy of the nomogram was confirmed. Conclusion The accuracy makes this freely-available, nomogram-based online tool useful to predict nodal pCR after NAC, translating the concept of tailored axillary surgery also in this setting of patients., Highlights • Axillary surgery after neoadjuvant chemotherapy in breast cancer is still debated. • Several surgical approaches are reported but clear evidences are lacking. • Prediction of axillary status after neoadjuvant chemotherapy is a clinical need. • An nomogram was developed and validated to preoperatively identify ypN0 patients. • This online tool could allow de-escalation of axillary surgery.

Introduction: Spider bites are common worldwide. Frequently symptoms resolve without any adverse outcome, but in rare cases the bite can cause severe morbidity. The most typical presentation of Mediterranean recluse spider (Loxosceles Rufescens) bite is a dermatonecrotic lesion of the skin (skin loxoscelism). When the only manifestation of a spider bite is an ulcerated skin lesion, clinical suspicion and differential diagnosis strongly depend on its site. We present the case of an ulcerated wound of the breast, diagnosed as a Mediterranean recluse spider bite. Case presentation: A 79-year-old woman presented a 10cm-wide soft tissue ulceration of her left breast. At first, the diagnostic hypothesis of an ulcerated cancer was ruled out. Two family members revealed a recent history of Mediterranean recluse spider bite and the same clinical diagnosis was made for our patient. A wide excision was performed, with complete resolution of symptoms. Discussion: No specific diagnostic criteria for spider bites are available. Diagnosis is usually clinical. Skin loxoscelism could be easily mistaken for cellulitis, various types of skin infections, cutaneous anthrax, vasculitis, scorpion sting, pyoderma gangrenosum, erythema migrans of Lyme disease or prurigo nodularis. A thorough anamnestic interview is fundamental to raise the diagnostic hypothesis. When possible, a biopsy is recommended and it is extremely important when the ulcer can mimic a cancer, as is the case in breast tissue. Conclusion: We recommend a wide excision of the wound after failure of conservative treatment, in order to obtain local control and to perform histological examination on a more representative specimen.

Background: Nipple Adenoma is a very uncommon, benign neoplasm that involves the nipple. Generally, complete surgical excision of the nipple is the main treatment, alternative therapeutic methods such as Mohs micrographic surgery, nipple splitting enucleation, and cryotherapy can be considered. Benign disorders of the breast generally occur in the breast of young women. Even if the management during pregnancy is usually conservative and surgical excision is reserved for very strong malignancy suspicion, benign lesions can cause the impossibility to breastfeed after giving birth when involving the nipple. Case Presentation: Here, we report a case of a 28-year-old woman with a 12-month history of progressive enlargement of the left nipple associated with erythema and intermittent serous-haematic discharge. The diagnostic assessment came out in favor of a nipple adenoma. After surgical treatment was recommended, the patient got pregnant. Surgical excision of nipple adenoma without complete resection of the nipple was performed after her first trimester of pregnancy under local anesthesia. A histopathological examination confirmed the diagnosis. No recurrence occurred after 12 months. The patient gave birth, had no deficit in lactation, and successfully breastfed. Conclusions: Therefore, we consider that nipple adenoma enucleation might be a safe treatment even during pregnancy. Moreover, conservative local treatment of nipple adenomas can preserve the nipple aesthetically and functionally, thus allowing regular lactation and breastfeeding in young women.

This article deals with the technologies and apps that asylum seekers need to navigate as forced hindered techno-users in order to get access to asylum and financial support. With a focus on the Greek refugee system, it discusses the multiple technological intermediations that asylum seekers face when dealing with the cash assistance programme and how asylum seekers are obstructed in accessing asylum and financial support. It explores the widespread disorientation that asylum seekers experience as they navigate un-legible techno-scripts that change over time. The article critically engages with the literature on the securitization and victimization of refugees, and it argues that asylum seekers are not treated exclusively as potential threats or as victims, but also as forced hindered subjects; that is, they are kept in a condition of protracted uncertainty during which they must find out the multiple technological and bureaucratic steps they are requested to comply with. In the final section, the article illustrates how forced technological mediations actually reinforce asylum seekers’ dependence on humanitarian actors and enhance socio-legal precarity.

This paper argues that COVID-19 has triggered a multiplication of heterogeneous bordering mechanisms that, far from stopping movement as such, have enhanced hierarchies of mobility. In particular, it shows that a confinement continuum has been put in place in the name of the “contain to protect” principle: migrants have been subjected to protracted lockdown measures in the name of their own protection. The piece concludes by interrogating how to rearticulate critique in COVID times in light of the enforcement of discriminatory “passports to freedom” (COVID-19 travel certificates).

This article advances a genealogy of migrant struggles and citizens solidarity practices, with a focus on the French-Italian migrant passage. It contends that scholarship has mainly mobilised a spatial approach to migrant struggles, while the temporality of solidarity and the collective memory of struggles have remained under-theorised. Then, the article moves on by focusing on the French-Italian Alpine border and it analyses the longstanding history of migrants’ passages there and, jointly, the mobilisations that took place in that area over the last decades exploring how these sedimented a citizen collective memory of solidarity practices. The final section deals with the history of mountain rescue at the French-Italian Alpine border and shows how migrants were saved by volunteers. The piece concludes by arguing that an insight into the memory of migrant struggles and solidarity practices enables foregrounding the transversal alliances which have been built between migrants and citizens and unsettling binary opposition between the former and the latter.

Coordinated and Edited by: N De Genova, M Tazzioli Co-Authored by: Claudia Aradau, Brenna Bhandar, Manuela Bojadzijev, Josue David Cisneros, N De Genova, Julia Eckert, Elena Fontanari, Tanya Golash-Boza, Jef Huysmans, Shahram Khosravi, Clara Lecadet, Patrisia Macias-Rojas, Federica Mazzara, Anne McNevin, Peter Nyers, Stephan Scheel, Nandita Sharma, Maurice Stierl, Vicki Squire, M Tazzioli, Huub van Baar and William Walters

Coordinated and Edited by:\ud N De Genova, M Tazzioli\ud \ud Co-Authored by:\ud Claudia Aradau, Brenna Bhandar, Manuela Bojadzijev, Josue David Cisneros, N De Genova, Julia Eckert, Elena Fontanari, Tanya Golash-Boza, Jef Huysmans, Shahram Khosravi, Clara Lecadet, Patrisia Macías-Rojas, Federica Mazzara, Anne McNevin, Peter Nyers, Stephan Scheel, Nandita Sharma, Maurice Stierl, Vicki Squire, M Tazzioli, Huub van Baar and William Walters

BACKGROUND/AIM: Extraordinary restrictions aimed to limit Sars-CoV-2 spreading; they imposed a total reorganization of the health-system. Oncological treatments experienced a significant slowdown. The aim of our multicentric retrospective study was to evaluate screening suspension and surgical treatment delay during COVID-19 and the impact on breast cancer presentation. PATIENTS AND METHODS: All patients who underwent breast surgery from March 11, 2020 to May 30, 2020 were evaluated and considered as the Lockdown group. These patients were compared with similar patients of the previous year, the Pre-Lockdown group. RESULTS: A total of 432 patients were evaluated; n=223 and n=209 in the Lockdown and Pre-lockdown-groups, respectively. At univariate analysis, waiting times, lymph-nodes involvement and cancer grading, showed a statistically significant difference (p

Background: Achieving a reliable venous access in a particular subset of patients and/or in emergency settings can be challenging and time-consuming. Furthermore, many hospitalized patients do not meet the criteria for central venous catheter positioning, unless an upgrade of the treatment is further needed. The mini-midline catheter has already showed to be reliable and safe as a stand-alone device, since it is easily and rapidly inserted and can indwell up to 1 month. Methods: In this further case series, we retrospectively evaluated data from 63 patients where a previously inserted mini-midline catheter was upgraded to a central venous catheter (the devices inserted in the arm replaced by peripherally inserted central catheter and others inserted “off-label” in the internal jugular replaced by single lumen centrally inserted central catheter), being used as introducer for the Seldinger guidewire. Results: The guidewire replacement was been made even early (after 1 day) or late (more than 10 days), usually following a need for an upgrade in treatment. No early or late complications were reported. Conclusion: According to the preliminary data we collected, this converting procedure seems to be feasible and risk-free, since neither infectious nor thrombotic complications were reported.

This article deals with the political legacy of migrants’ spaces across Europe that are the outcome of border enforcement policies but that are also shaped by migrants’ struggles and movements. It interrogates what is left, after their vanishing forced eviction, at the level of spatial-political traces, as well as in the collective memory of the citizens of those places. The main argument of the piece is that in order to come to grips with these spaces beyond their ephemeral dimension, we need to consider the temporality of migrant struggles and of solidarity practices – between migrants and citizens. The article focuses, first, on the French-Italian Alpine border, and analyses how the sedimented memory of the struggles in that valley has been reactivated in the present to support the migrants in transit. Then, the article moves on by developing the notion of transversal alliances through an insight into the Gilets Noirs movement in France, a collective of undocumented migrants which mobilised towards getting to permit to stay and accommodation, while at the same time framing their struggle as a broader battle against precarity and exploitation. The piece concludes suggesting that by bringing in the genealogy of struggles and solidarity practices, migrants’ spaces appear as part of a precarious mobile common in the making.

Risk-reducing-salpingo-oophorectomy (RRSO) inevitably leads BRCA mutation carriers to premature menopause.To evaluate the existing evidence for use of postmenopausal hormone therapy (HT) in BRCAmc, after RRSO or menopause occurring naturally, for both breast cancer (BC) survivors and those without BC.All BC survivors are excluded from any HT treatment: in other BRCAmc, before 51 years of age the benefits of HT overcome the risks after RRSO and/or premature ovarian insufficiency (POF). After 51 years of age, it is important to treat only women with important vasomotor symptoms, after the failure of alternative therapies. Estrogens-only therapy plays a key role in hysterectomized women (HW). In the case of an intact uterus (UW), associations with the lowest dose of progestins/natural progesterone derivatives have to be preferred, as progestins has been shown to play an important role in BC transformation, especially in BRCA1mc. No studies have been performed in BRCAmc with regard to 'progestin-free' HT, in particular the old tibolone (both in HW and UW) and the new tissue-selective estrogen complex (in UW). However, preliminary data obtained from the general population are reassuring about the use of these 'progestin-free' preparations and BC safety.