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493 results on '"Targarona, Eduardo"'

113. Colonic stenting as a bridge to surgery versus emergency surgery for malignant colonic obstruction: results of a multicentre randomised controlled trial (ESCO trial)

Author

Arezzo, Alberto, primary, Balague, Carmen, additional, Targarona, Eduardo, additional, Borghi, Felice, additional, Giraudo, Giorgio, additional, Ghezzo, Luigi, additional, Arroyo, Antonio, additional, Sola-Vera, Javier, additional, De Paolis, Paolo, additional, Bossotti, Maurizio, additional, Bannone, Elisa, additional, Forcignanò, Edoardo, additional, Bonino, Marco Augusto, additional, Passera, Roberto, additional, and Morino, Mario, additional

Published
2016
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119. Effectiveness of Laparoscopic Surgery for Gallstones and Common Bile Duct Lithiasis: a Systematic Overview

Author

Manterola, Carlos, Pineda, Viviana, Tort, Montserrat, Targarona, Eduardo, Villegas Portero, Román, and Alonso, Pablo

Subjects
Biomedical, Cholecystolithiasis, Colecistolitiasis, Evaluación de tecnología sanitaria, Gallstones, Coledocolitiasis, Laparoscopia, Choledocholithiasis, Laparoscopic, Cálculos biliares, Cholelithiasis, Technology Assessment, Colelitiasis, Laparoscopy, Cholecystectomy, Colecistectomía laparoscópica
Abstract

The aim of the present study was to evaluate the available evidence on the effectiveness of laparoscopic surgery for treating gallstones and common bile duct lithiasis (CBDL). A systematic overview was performed. Medline, EMBASE and The Cochrane Library were searched (1998-2008). Systematic reviews (SR), clinical practice guidelines (CPG), randomised clinical trials (RCT) and observational studies were included. Internal validity and overall quality of the evidence were assessed. The available evidence was classified according to the Oxford Centre for Evidence Based Medicine proposal. 87 studies were included in this review (12 SR, 23 RCT, 3 CPG, 13 cohort studies, 3 cross-sectional studies, 2 case and control studies and 31 case series). Compared with open cholecystectomy, laparoscopic cholecystectomy (LC) is associated with shorter operating time, shorter hospital stay and better quality of life (high quality evidence). The use of antibiotic prophylaxis does not appear to reduce the infection rate in low-risk patients (high quality evidence). Although many techniques have been advocated to perform LC their effectiveness is as yet inconclusive (low-quality evidence). Two-stage surgery is the most appropriate strategy for high-risk patients with CBDL (high-quality evidence). Mortality is similar to open surgery, as the effectiveness is similar to that of endoscopic treatment (high-quality evidence). As a conclusion we can state that the evidence concerning the effectiveness of laparoscopic surgery for gallstones and CBDL is scarce and of low methodological quality and that better quality studies are warranted to assess these techniques more adequately. El objetivo del presente estudio fue evaluar la evidencia disponible respecto de la efectividad de la cirugía laparoscópica en el tratamiento de la colelitiasis y la litiasis de la vía biliar (LVBP). Para ello, se realizó una revisión global de la evidencia disponible. Se realizaron búsquedas en las bases de datos MEDLINE, EMBASE y The Cochrane Library (1998-2008). Se incluyeron guías de práctica clínica (GPC), revisiones sistemáticas (RS), ensayos clínicos con asignación aleatoria (EC) y estudios observacionales. Se valoró la validez interna y la calidad global de los estudios. Los datos disponibles y la evidencia generada se clasificaron en base a la propuesta del Centro de Oxford de Medicina Basada en la Evidencia. 87 estudios fueron incluidos en esta revisión (3 GPC, 12 RS, 23 EC, 13 estudios de cohortes, 3 estudios transversales, 2 estudios de casos y de controles y 31 series de casos). En comparación con la colecistectomía abierta, la colecistectomía laparoscópica (CL) se asocia con menor tiempo operatorio y estancia hospitalaria y mejor calidad de vida (evidencia de alta calidad). El uso de profilaxis antibiótica no parece reducir la tasa de infección en pacientes de bajo riesgo (evidencia de alta calidad). Aunque se han descrito numerosas técnicas para realizar una CL, su eficacia no es aún concluyente (evidencia de baja calidad). La cirugía en dos etapas es la estrategia más adecuada para los pacientes de alto riesgo con LVBP (evidencia de alta calidad). La mortalidad del tratamiento laparoscópico de la LVBP es similar a la de la cirugía abierta; y como su eficacia es similar a la del tratamiento endoscópico (evidencia de alta calidad). Se puede concluir señalando que la evidencia disponible respecto de la efectividad de la cirugía laparoscópica para el tratamiento de la colelitiasis y la LVBP es escasa y de baja calidad metodológica; y que se requieren estudios de mejor calidad para valorar de forma más apropiada estas técnicas.

Published
2010

120. Effectiveness of Laparoscopic Surgery for Gallstones and Common Bile Duct Lithiasis: a Systematic Overview

Author

Manterola,Carlos, Pineda,Viviana, Tort,Montserrat, Targarona,Eduardo, Villegas Portero,Román, and Alonso,Pablo

Subjects
Choledocholithiasis, Laparoscopic, Biomedical, Cholelithiasis, Technology Assessment, Cholecystolithiasis, Laparoscopy, Cholecystectomy, Gallstones
Abstract

The aim of the present study was to evaluate the available evidence on the effectiveness of laparoscopic surgery for treating gallstones and common bile duct lithiasis (CBDL). A systematic overview was performed. Medline, EMBASE and The Cochrane Library were searched (1998-2008). Systematic reviews (SR), clinical practice guidelines (CPG), randomised clinical trials (RCT) and observational studies were included. Internal validity and overall quality of the evidence were assessed. The available evidence was classified according to the Oxford Centre for Evidence Based Medicine proposal. 87 studies were included in this review (12 SR, 23 RCT, 3 CPG, 13 cohort studies, 3 cross-sectional studies, 2 case and control studies and 31 case series). Compared with open cholecystectomy, laparoscopic cholecystectomy (LC) is associated with shorter operating time, shorter hospital stay and better quality of life (high quality evidence). The use of antibiotic prophylaxis does not appear to reduce the infection rate in low-risk patients (high quality evidence). Although many techniques have been advocated to perform LC their effectiveness is as yet inconclusive (low-quality evidence). Two-stage surgery is the most appropriate strategy for high-risk patients with CBDL (high-quality evidence). Mortality is similar to open surgery, as the effectiveness is similar to that of endoscopic treatment (high-quality evidence). As a conclusion we can state that the evidence concerning the effectiveness of laparoscopic surgery for gallstones and CBDL is scarce and of low methodological quality and that better quality studies are warranted to assess these techniques more adequately.

Published
2010

124. Commentary 2

Author

Targarona, Eduardo M, primary, Balagué, Carmen, additional, and Trias, Manuel, additional

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125. Xavier Feliú Palá

Author

Targarona, Eduardo M., primary, Morales Conde, Salvador, additional, Salvador Sanchis, José Luis, additional, Veloso Veloso, Enrique, additional, Torres, Antonio J., additional, Ramirez Felipe, José, additional, and Balague, Carmen, additional

Published
2014
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131. Surgical approach

Author

Targarona, Eduardo M, primary, Monclova, Julio Lopez, additional, Luppi, Carlos Rodriguez, additional, Balagué, Carmen, additional, and Trías, Manuel, additional

Published
2013
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134. Prognostic value of BRAF and KRAS mutations in colorectal cancer patients.

Author

Murata, Paola, primary, Stradella, Agostina, additional, Páez, David, additional, Tobeña, Maria, additional, Sebio, Ana, additional, Paré, Laia, additional, González, Alan, additional, Espinosa, Iñigo, additional, Targarona, Eduardo, additional, Gich, Ignasi, additional, Barnadas, Agust, additional, Baiget, Montserrat, additional, and Martin-Richard, Marta, additional

Published
2012
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144. Fístula ileouretral

Author

Urdaneta, Gabriel, primary, Targarona, Eduardo M., additional, Martínez, Carmen, additional, and Trias, Manuel, additional

Published
2009
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148. McKittrick-Wheelock Syndrome Treated by Laparoscopy

Author

Targarona, Eduardo M., primary, Hernandez, Pilar M., additional, Balague, Carmen, additional, Martinez, Carmen, additional, Hernández, J., additional, Pulido, Daniel, additional, Berindoague, Rene, additional, and Trias, Manuel, additional

Published
2008
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