Search

Your search keyword '"Tanaka, Takehiro"' showing total 980 results
Start Over Author "Tanaka, Takehiro"
980 results on '"Tanaka, Takehiro"'

110. A Granulation Polyp in the Colon Masquerading as Metastatic Cancer

Author

Iwamuro, Masaya, Takahara, Masahiro, Yamazaki, Tatsuhiro, Tanaka, Takehiro, Kondo, Yoshitaka, Hiraoka, Sakiko, and Okada, Hiroyuki

Subjects
colonoscopy, colonic neoplasms, granulation polyp, digestive system diseases
Abstract

A 60-year-old Caucasian male was diagnosed with lung adenocarcinoma and multiple metastases to the bone, spleen, and brain. He underwent radiotherapy for the brain and lumbar spine metastases, plus chemotherapy (cisplatin and pemetrexed). The chemotherapy was discontinued due to vomiting and hyponatremia, and nivolumab was then administered. Eight months later, 18F-fluorodeoxyglucose positron emission tomography showed tracer uptake in the colon. Colonoscopy revealed a reddish multinodular polyp in the sigmoid colon. The polyp showed irregular microvessels. No colonic mucosal surface structures were observed. Colonic metastasis of the lung carcinoma was highly suspected; the polyp was therefore surgically removed. The histological analysis revealed granulation tissue and suppurative inflammation without neoplastic changes. We diagnosed the lesion as a granulation polyp. Despite the difficulty in diagnosing these lesions due to their rarity and similarity to metastatic colon tumors, we suggest that recognizing the endoscopic features of the polyp surface may allow a preoperative diagnosis.

Published
2019

111. Histologic Transformation from Follicular Lymphoma to Diffuse Large B-cell Lymphoma Detected during Colonoscopy

Author

Iwamuro, Masaya, Yamasaki, Yasushi, Tanaka, Takehiro, Asada, Noboru, Matsuoka, Ken-ichi, Hiraoka, Sakiko, Kawahara, Yoshiro, and Okada, Hiroyuki

Subjects
follicular lymphoma, Lymphoma, diffuse large B-cell lymphoma, histologic transformation, Humans, Female, Colonoscopy, Lymphoma, Large B-Cell, Diffuse, Colorectal Neoplasms, Lymphoma, Follicular, colorectal lymphoma, Aged
Abstract

A 77-year-old Japanese woman who had been treated for follicular lymphoma for 8 years developed abdominal pain and intra-abdominal lymphadenopathies. Colonoscopy revealed an elevated lesion in the rectum, which presented as two humps with erosions. A diagnosis of histologic transformation of follicular lymphoma to diffuse large B-cell lymphoma was made by endoscopic biopsy. This case underscores the importance of endoscopy examinations and biopsy of newly emerged gastrointestinal lesions for the prompt diagnosis of histologic transformation, since salvage chemotherapy must be initiated quickly in such cases.

Published
2021

112. Practical study on Japanese building construction management by avoiding risk to environment and safety

Author

Wariishi Hiroyuki and Tanaka Takehiro

Subjects
Environmental sciences, GE1-350
Abstract

It is essential in building construction management to prevent risk from the viewpoint of both environment and safety. This study suggests the significance of building construction management which places emphasis on risk prevention for the sake of environment and safety, with the introduction of Japanese efficient operation methods to simultaneously conduct environmental management, safety management and risk management, in addition to practical measures for heatstroke which is a serious summer issue of building construction management.

Published
2018
Full Text
View/download PDF

113. Examination on risk prevention measures for environment and safety of food plants in Japan

Author

Liu Ze and Tanaka Takehiro

Subjects
Environmental sciences, GE1-350
Abstract

Risk prevention measures to secure both pleasant environment and safety are indispensable particularly to food plants. In this study, current situations and causes of troubles, affairs and accidents which have taken place in Japanese food plants are reviewed. In addition, the introduction of human-based strategies integrated with IT/IoT technologies as well as sampling methods for airborne microbes which have been being highlighted these days is proposed as measures to protect environment and safety of food plants.

Published
2018
Full Text
View/download PDF

115. Fever and electrocoagulation syndrome after colorectal endoscopic submucosal dissection for patients with immunosuppressants and steroids

Author

Yamamoto, Shumpei, primary, Kinugasa, Hideaki, additional, Yamasaki, Yasushi, additional, Hirai, Mami, additional, Ako, Soichiro, additional, Takei, Kensuke, additional, Igawa, Shoko, additional, Yasutomi, Eriko, additional, Oka, Shohei, additional, Ohmori, Masayasu, additional, Inokuchi, Toshihiro, additional, Harada, Keita, additional, Hiraoka, Sakiko, additional, Nouso, Kazuhiro, additional, Tanaka, Takehiro, additional, and Okada, Hiroyuki, additional

Published
2021
Full Text
View/download PDF

119. Assessment of the Concordance Rate between Intraoperative Pathological Diagnosis and the Final Pathological Diagnosis of Spinal Cord Tumors

Author

Muraoka, Sosuke, Yamane, Kentaro, Misawa, Haruo, Takigawa, Tomoyuki, Tetsunaga, Tomoko, Oda, Yoshiaki, Nakanishi, Kazuo, Ozaki, Toshifumi, and Tanaka, Takehiro

Subjects
Adult, spinal cord tumor, intraoperative pathological diagnosis, Biopsy, final pathological diagnosis, concordance rate, Humans, Female, Spinal Cord Neoplasms, bacterial infections and mycoses, Magnetic Resonance Imaging, Aged
Abstract

The intraoperative pathological diagnosis (IPD) plays an important role in determining the optimal surgical treatment for spinal cord tumors. The final pathological diagnosis (FPD) is sometimes different from the IPD. Here, we sought to identify the accuracy of the IPD of spinal cord tumors compared to the FPD. We retrospec-tively analyzed the cases of 108 patients with spinal cord tumors treated surgically in our institute; the IPD, FPD, mismatched cases, and concordance rate between the IPD and FPD were investigated. Five cases involved a mismatch between the IPD and FPD. The overall concordance rate was 95.4%, with 90.9% for extra-dural lesions, 98.5% for intradural extramedullary lesions, 84.2% for intramedullary lesions, and 100% for dumbbell-type tumors. The concordance rate of intramedullary lesions tended to be lower than that of other lesions (p = 0.096). A lower concordance rate was revealed for intramedullary lesions compared to the other lesions. Despite the IPD clearly remaining a valuable tool during operative procedures, surgeons should recog-nize the limitations of IPDs and make comprehensive decisions about surgical treatments.

Published
2021

122. Ramucirumab in second‑line advanced colorectal cancer therapy: A study on therapeutic outcomes and hepatic sinusoidal platelet aggregation.

Author

Kimura, Keisuke, Katata, Yosuke, Umeda, Yuzo, Tanaka, Takehiro, Yano, Shuya, Yoshida, Kazuhiro, Fujiwara, Toshiyoshi, Mori, Yoshiko, Yamada, Takeshi, and Nagasaka, Takeshi

Subjects
COLORECTAL liver metastasis, TREATMENT effectiveness, BLOOD platelet aggregation, CANCER treatment, OVERALL survival
Abstract

The present study investigated the role of ramucirumab (RAM) in treating liver metastases (LMs) as a second-line or salvage treatment in patients with advanced CRC. Of the 36 patients, 21 (58%) received RAM plus folinic acid, fluorouracil and irinotecan (FOLFIRI) as second-line treatment, whereas 15 (42%) received it in a salvage setting. The median overall survival time was 23 months [95% confidence interval (CI), 12–34 months] for those in the second-line treatment group and 8 months (95% CI, 5–19 months) for those in the salvage treatment group. Of the 36 patients, 14 (39%) underwent surgical resection of LMs during chemotherapy. A total of 6 patients underwent surgical resection for LMs for the first time during second-line RAM plus FOLFIRI (RAM-LM); of the remaining 8 patients, 6 underwent resection of LMs during first-line bevacizumab (BEV)-based chemotherapy (BEV-LM). Immunohistochemical analysis of CD42b showed that the platelet aggregation score (CD42b score), which ranges from 0 (absence of deposition) to 3 (presence of linear deposition), tended to decrease with the increasing duration of treatment with both RAM and BEV. Although there was no significant difference in the mean duration of anti-VEGF antibody treatment between the BEV-LM and RAM-LM groups, the median CD42b score was higher in the RAM-LM group (median CD42b score, 3; range, 0–3) compared with that in the BEV-LM group (median CD42b score, 1; range, 0–3; P=0.01), suggesting that RAM induces a different degree of platelet aggregation in liver sinusoids compared to BEV. [ABSTRACT FROM AUTHOR]

Published
2024
Full Text
View/download PDF

124. Clinical and phenotypical characteristics of submucosal invasive carcinoma in non-ampullary duodenal cancer

Author

Matsueda, Katsunori, primary, Kanzaki, Hiromitsu, additional, Takenaka, Ryuta, additional, Nakagawa, Masahiro, additional, Matsueda, Kazuhiro, additional, Iwamuro, Masaya, additional, Kawano, Seiji, additional, Kawahara, Yoshiro, additional, Toji, Tomohiro, additional, Tanaka, Takehiro, additional, Yagi, Takahito, additional, Fujiwara, Toshiyoshi, additional, and Okada, Hiroyuki, additional

Published
2021
Full Text
View/download PDF

127. Pathological and clinical effects of interleukin-6 on human myocarditis

Author

Amioka, Naofumi, primary, Nakamura, Kazufumi, additional, Kimura, Tomonari, additional, Ohta-Ogo, Keiko, additional, Tanaka, Takehiro, additional, Toji, Tomohiro, additional, Akagi, Satoshi, additional, Nakagawa, Koji, additional, Toh, Norihisa, additional, Yoshida, Masashi, additional, Miyoshi, Toru, additional, Nishii, Nobuhiro, additional, Watanabe, Atsuyuki, additional, Asano, Ryotaro, additional, Ogo, Takeshi, additional, Nakaoka, Yoshikazu, additional, Morita, Hiroshi, additional, Yanai, Hiroyuki, additional, and Ito, Hiroshi, additional

Published
2021
Full Text
View/download PDF

129. Randomized trial comparing the 25G and 22G Franseen needles in endoscopic ultrasound‐guided tissue acquisition from solid pancreatic masses for adequate histological assessment

Author

Tomoda, Takeshi, primary, Kato, Hironari, additional, Fujii, Yuuki, additional, Yamazaki, Tatsuhiro, additional, Matsumoto, Kazuyuki, additional, Horiguchi, Shigeru, additional, Tsutsumi, Koichiro, additional, Inoue, Hirofumi, additional, Tanaka, Takehiro, additional, Mitsuhashi, Toshiharu, additional, and Okada, Hiroyuki, additional

Published
2021
Full Text
View/download PDF

133. A Case of Myoepithelial Hamartoma: Morphological Variation Supported by OCT4 Expression

Author

Tanaka, Takehiro, Nishida, Kenji, Iwamuro, Masaya, Kikuchi, Satoru, and Yoshino, Tadashi

Subjects
Article Subject
Abstract

In this report, we describe a patient with myoepithelial hamartoma, which is regarded as synonymous with adenomyosis and heterotopic pancreas. Endoscopy revealed a submucosal tumor in the antrum of the stomach. Subsequently, distal gastrectomy with Roux-en-Y reconstruction was performed. Histological findings of adenomyomatous lesion and heterotopic pancreatic tissue were observed in this lesion. The distribution of OCT4, which is a pluripotency marker, varied in each part.

Published
2021
Full Text
View/download PDF

137. SMAD4 Germline Pathogenic Variant-Related Gastric Juvenile Polyposis with Adenocarcinoma Treated with Laparoscopic Total Gastrectomy: A Case Report

Author

Sakurai, Yuya, primary, Kikuchi, Satoru, additional, Shigeyasu, Kunitoshi, additional, Kakiuchi, Yoshihiko, additional, Tanaka, Takehiro, additional, Umeda, Hibiki, additional, Sakamoto, Masaki, additional, Takeda, Sho, additional, Yano, Shuya, additional, Futagawa, Mashu, additional, Kato, Fumino, additional, Sogawa, Reimi, additional, Yamamoto, Hideki, additional, Kuroda, Shinji, additional, Kondo, Yoshitaka, additional, Teraishi, Fuminori, additional, Kishimoto, Hiroyuki, additional, Nishizaki, Masahiko, additional, Kagawa, Shunsuke, additional, Hirasawa, Akira, additional, and Fujiwara, Toshiyoshi, additional

Published
2021
Full Text
View/download PDF

138. Linked Color Imaging (LCI) Emphasizes the Color Changes in the Gastric Mucosa After Helicobacter pylori Eradication

Author

Sakae, Hiroyuki, primary, Kanzaki, Hiromitsu, additional, Satomi, Takuya, additional, Okanoue, Shotaro, additional, Obayashi, Yuka, additional, Hamada, Kenta, additional, Abe, Makoto, additional, Kono, Yoshiyasu, additional, Miura, Ko, additional, Iwamuro, Masaya, additional, Kawano, Seiji, additional, Kawahara, Yoshiro, additional, Tanaka, Takehiro, additional, Yanai, Hiroyuki, additional, and Okada, Hiroyuki, additional

Published
2021
Full Text
View/download PDF

139. Risk Factors for Gastric Cancer after the Eradication of Helicobacter pylori Evaluated Based on the Background Gastric Mucosa: A Propensity Score-matched Case-control Study

Author

Obayashi, Yuka, primary, Kawano, Seiji, additional, Sakae, Hiroyuki, additional, Abe, Makoto, additional, Kono, Yoshiyasu, additional, Kanzaki, Hiromitsu, additional, Iwamuro, Masaya, additional, Kawahara, Yoshiro, additional, Tanaka, Takehiro, additional, Yanai, Hiroyuki, additional, and Okada, Hiroyuki, additional

Published
2021
Full Text
View/download PDF

143. Multicentric Castleman's disease with abundant IgG4-positive cells: a clinical and pathological analysis of six cases

Author

Sato, Yasuharu, Kojima, Masaru, Takata, Katsuyoshi, Morito, Toshiaki, Mizobuchi, Kohichi, Tanaka, Takehiro, Inoue, Dai, Shiomi, Hideyuki, Iwao, Haruka, and Yoshino, Tadashi

Subjects
Lymphoproliferative disorders -- Diagnosis, Lymphoproliferative disorders -- Development and progression, Lymphoproliferative disorders -- Reports, Immunoglobulin G -- Physiological aspects, Immunoglobulin G -- Analysis, Health
Published
2010

147. Microsatellite Instability Analysis and Its Prognostic Value in Invasive Nonampullary Duodenal Adenocarcinoma.

Author

Yang, Guang, Tanaka, Takehiro, Kinugasa, Hideaki, Kanzaki, Hiromitsu, Chen, Meng-Xi, Ichimura, Koichi, Nakagawa, Masahiro, Jin, Zai-Shun, Zheng, Ru-yi, and Yoshino, Tadashi

Subjects
*ADENOCARCINOMA, *CELL differentiation, *STATISTICS, *PATHOGENESIS, *DUODENAL tumors, *CONFIDENCE intervals, *IMMUNOHISTOCHEMISTRY, *MULTIVARIATE analysis, *RETROSPECTIVE studies, *TUMOR classification, *DESCRIPTIVE statistics, *KAPLAN-Meier estimator, *SURVIVAL analysis (Biometry), *TUMOR markers, *POLYMERASE chain reaction, *PHENOTYPES, *RARE diseases
Abstract

Purpose: Nonampullary duodenal adenocarcinoma (NADA) is a rare disease. Although several prognostic factors have been reported for this disease, they remain controversial due to their rarity. In this study, we retrospectively analyzed 54 cases of invasive NADA, focusing on the microsatellite instability (MSI) phenotype, programmed cell death-ligand 1 (PD-L1) expression, and prognostic factors. Methods: Expression of the PD-L1 protein and cell differentiation markers in tumors was detected by immunohistochemistry. Microsatellite markers (NR-21, NR-22, NR-24, BAT-25, and BAT-26) were amplified for MSI assessment by PCR. Results: The incidence of MSI in invasive NADA was 35.2%. No significant correlation between the MSI phenotype and clinicopathological factors was observed. Positive expression of PD-L1 by immune cells was common in advanced-stage disease (p = 0.054), and positive expression of PD-L1 in cancer cells correlated significantly with the histologically undifferentiated type (p = 0.016). Kaplan-Meier survival analysis demonstrated a significantly better overall survival (OS) in patients with MSI (p = 0.013) and at early-stage disease (p = 0.000) than in those with microsatellite-stable or at late tumor stages. Univariate and multivariate analyses showed that MSI (hazard ratio [HR]: 0.282, 95% confidence interval [CI]: 0.106–0.751, p = 0.011) and early tumor stage (stage I-II) (HR: 8.81, 95% CI: 2.545–30.500, p = 0.001) were independent better prognostic factors of OS. Conclusions: MSI and early tumor stage (stage I-II) were independent better prognostic factors of OS. A high proportion of MSI phenotypes and positive PD-L1 expression may be helpful for identifying immune checkpoint inhibitors as a novel therapeutic strategy. [ABSTRACT FROM AUTHOR]

Published
2022
Full Text
View/download PDF

148. Efficacy and safety of endoscopic submucosal dissection for gastric tube cancer: A multicenter retrospective study

Author

Satomi, Takuya, primary, Kawano, Seiji, additional, Inaba, Tomoki, additional, Nakagawa, Masahiro, additional, Mouri, Hirokazu, additional, Yoshioka, Masao, additional, Tanaka, Shoichi, additional, Toyokawa, Tatsuya, additional, Kobayashi, Sayo, additional, Tanaka, Takehiro, additional, Kanzaki, Hiromitsu, additional, Iwamuro, Masaya, additional, Kawahara, Yoshiro, additional, and Okada, Hiroyuki, additional

Published
2021
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results