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The children's game Corona appeared spontaneously at the beginning of 2020 within a small folklore community of lower grade pupils at the “St. Sava” Elementary School in the Belgrade’s municipality of Vračar. Sudden changes in the daily routines of the community members created a need for controlled articulation of accumulated tension generated during the COVID-19 pandemic. As a sociocultural construct the chasing game of Corona underwent various modifications during the two academic years covered by our research (2020 and 2021), due to the changes that took place in the micro and macro sociocultural environment. Generally, the chasing games are common to children and they have an important developmental function, since they encourage the improvement of adaptive abilities and the agility in successful locomotor responses to stimuli from the external environment. Although the semiotic code of this type of games is based on the hunter ‒ prey relation, the game Corona belongs to a specific subtype of chasing games that is related to the idea of progressive spread of infectious disease, just as the traditional game of šugice/šuge (Serbian for Tag; literally, ’scabies’). The examples of this type of games have been observed in various parts of the world, where they refer to various infectious diseases: the plague, Spanish fever, leprosy, polio. All these games have their roots in the traumatic collective experiences of dealing with epidemics. The basic semiotic code (hunter‒prey relation) has undergone a secondary semiotization in this type of games, shifting to the binary opposition sick: healthy. However, they both stem from the same binary oppositions such as life: death; human : demonic; we: others. As the children's game Corona entails communication based on a set of symbolic actions, it operates as a "capacitor" of cultural and semiotic memory. It brings contents from deeper diachronic layers, actualizing cultural experience accumulated in the recent and distant past.

In recent years, virtual online communities have experienced rapid growth. These communities enable individuals to share and manage images or websites by employing tags. A collaborative tagging system (CTS) facilitates the process by which internet users collectively organize resources. CTS offers a plethora of useful information, including tags and timestamps, which can be utilized for recommendations. A tag represents an implicit evaluation of the user’s preference for a particular resource, while timestamps indicate changes in the user’s interests over time. As the amount of information increases, it is feasible to integrate more detailed data, such as tags and timestamps, to improve the quality of personalized recommendations. The current study employs collaborative filtering (CF), which incorporates both tag and time information to enhance recommendation precision. A computational recommender system is established to generate weights and calculate similarities by incorporating tag data and time. The effectiveness of our recommendation model was evaluated by linearly merging tag and time data. In addition, the proposed CF method was validated by applying it to big data sets in the real world. To assess its performance, the size of the neighborhood was adjusted in accordance with the standard CF procedure. The experimental results indicate that our proposed method significantly improves the quality of recommendations compared to the basic CF approach.

Obesity‐associated insulin resistance plays a major role in the pathogenesis of non‐alcoholic fatty liver disease (NAFLD). The accumulation of diacylglycerol (DAG), ceramides and inflammation are key factors that cause NAFLD. In recent years, the ketogenic diet (KD) has emerged as an effective non‐pharmacological intervention for the treatment of NAFLD and other obesity‐related metabolic disorders. What remains undetermined is how the KD affects DAG and ceramide content and insulin sensitivity in the liver. Thus, this research was designed to assess these variables, as well as glucose and fat metabolism and markers of inflammation in livers of rats exposed for 8 weeks to one of the following diets: standard chow (SC), obesogenic high‐fat, sucrose‐enriched diet (HFS) or a KD. Despite having a higher fat content than the HFS diet, the KD did not cause steatosis and preserved hepatic insulin signalling. The KD reduced DAG content and protein kinase C‐ε activity, but markedly increased liver ceramide content. However, whereas the KD increased ceramide synthase 2 (CerS2) expression, it suppressed CerS6 expression, an effect that promoted the production of beneficial very long‐chain ceramides instead of harmful long‐chain ceramides. The KD also enhanced the liver expression of key genes involved in mitochondrial biogenesis and fatty acid oxidation (Pgc‐1α and Fgf21), suppressed inflammatory genes (Tnfα, Nf‐kb, Tlr4 and Il6), and shifted substrate away from de novo lipogenesis. Thus, through multiple mechanisms the KD exerted anti‐steatogenic and insulin‐sensitizing effects in the liver, which supports the use of this dietary intervention to treat NAFLD. Key points: The accumulation of diacylglycerol (DAG), ceramides and inflammation are key factors that cause insulin resistance and non‐alcoholic fatty liver disease (NAFLD). This study provides evidence that a ketogenic diet (KD) rich in fat and devoid of carbohydrate reduced DAG content and preserved insulin signalling in the liver.The KD shifted metabolism away from lipogenesis by enhancing genes involved in mitochondrial biogenesis and fatty acid oxidations in the liver.The KD also promoted the production of beneficial very long‐chain ceramides instead of potentially harmful long‐chain ceramides.Through multiple mechanisms, the KD exerted anti‐steatogenic and insulin‐sensitizing effects in the liver, which supports the use of this dietary intervention to treat NAFLD. [ABSTRACT FROM AUTHOR]

Toll/Interleukin-1 receptor (TIR) domains are cytoplasmic domain that mediates receptor signalling. These domains are present in proteins like Toll-like receptors (TLR), its signaling adaptors and Interleukins, that form a major part of the immune system. These TIR domain containing signaling adaptors binds to the TLRs and interacts with their TIR domains for downstream signaling. We have examined the evolutionary divergence across the tree of life of two of these TIR domain containing adaptor molecules (TICAM) i.e., TIR domain-containing adapter-inducing interferon-β (TRIF/TICAM1) and TIR domain containing adaptor molecule2 (TRAM/TICAM2), by using computational approaches. We studied their orthologs, domain architecture, conserved motifs, and amino acid variations. Our study also adds a timeframe to infer the duplication of TICAM protein from Leptocardii and later divergence into TICAM1/TRIF and TICAM2/TRAM. More evidence of TRIF proteins was seen, but the absence of conserved co-existing domains such as TRIF-NTD, TIR, and RHIM domains in distant relatives hints on diversification and adaptation to different biological functions. TRAM was lost in Actinopteri and has conserved domain architecture of TIR across species except in Aves. An additional isoform of TRAM, TAG (TRAM adaptor with the GOLD domain), could be identified in species in the Mesozoic era. Finally, the Hypothesis based Likelihood ratio test was applied to look for selection pressure amongst orthologues of TRIF and TRAM to search for positively selected sites. These residues were mostly seen in the non-structural region of the proteins. Overall, this study unravels evolutionary information on the adaptors TRAM and TRIF and how well they had duplicated to perform diverse functions by changes in their domain architecture across lineages. [ABSTRACT FROM AUTHOR]

Triacylglycerol (TAG), which is a neutral lipid, has a structure in which three molecules of fatty acid (FA) are ester-bonded to one molecule of glycerol. TAG is important energy source for seed germination and seedling development in plants. Depending on the FA composition of the TAG, it is used as an edible oil or industrial material for cosmetics, soap, and lubricant. As the demand for plant oil is rising worldwide, either the type of FA must be changed or the total oil content of various plants must be increased. In this review, we discuss the regulation of FA metabolism by Clustered regularly interspaced short palindromic repeats (CRISPR)/Cas9, a recent genomeediting technology applicable to various plants. The development of plants with higher levels of oleic acid or lower levels of very long-chain fatty acids (VLCFAs) in seeds are discussed. In addition, the current status of research on acyltransferases, phospholipases, TAG lipases, and TAG synthesis in vegetative tissues is described. Finally, strategies for the application of CRISPR/Cas9 in lipid metabolism studies are mentioned. [ABSTRACT FROM AUTHOR]

At cash registers in Japanese supermarkets and convenience stores, one may see clerks wearing "In training" tags on their chest. The tag denotes an apprentice learning the job duties while working on the actual job. This study aimed to clarify the role of nametags from the perspectives of the three types of persons involved with the tags, that is, the persons looking at the clerks wearing them, the clerks wearing them, and the managers requesting the clerks to wear them. The results indicate that the custom of wearing such nametags is related to the rule of affixing beginner's marks to vehicles and is one of the Japanese forms of communication that requires consideration from others. [ABSTRACT FROM AUTHOR]

Abstract High feedstock cost and low oil yields per unit of land from temperate oilseed crops limit the growth of commercial‐scale biodiesel production. Recently, highly productive crops, such as sugarcane and energycane, have been engineered to accumulate triacylglycerides (TAGs) that allow the production of far more industrial vegetable oil than previously possible. A proof‐of‐concept suggests that biodiesel production from engineered energycane will be possible. However, before making efforts for scale‐up, it is critical to understand the commercial feasibility and economic competitiveness of this process. This study performs techno‐economic analysis of a unique biorefinery processing energycane to co‐produce biodiesel and ethanol. Comprehensive process simulation models were developed for two scenarios: (i) biodiesel from TAGs and ethanol from fermentation of sugars in juice and (ii) biodiesel from TAGs and ethanol from fermentation of sugars in juice and hydrolysis of carbohydrates in bagasse. Based on the target levels, the analysis was performed for energycane containing 0%, 5%, and 7.7% TAGs (d.b.). The biodiesel from engineered energycane was found economically viable and competitive to soybean biodiesel. Although the capital investment is higher compared to the soybean biodiesel plant, the biodiesel production costs ($0.66–$0.9/L) were lower than soybean biodiesel ($0.91/L). Biorefinery‐scenario‐1 processing energycane containing 7.7% TAG produces biodiesel with profitability (IRR 7.84) slightly lower than soybean biodiesel (IRR 8.3), but yields five times of biodiesel per unit land and is self‐sustainable for energy requirements. The surplus electricity can displace fossil electricity and provide environmental benefits. Monte Carlo simulation indicated that biorefinery is profitable with a 29%–65% probability (NPV > 0) which is largely controlled by feedstock composition and biodiesel market price. It is important to note that energycane can be grown on the marginal rainfed lands in S.E. USA, where soybean would not be viable. Biodiesel from engineered energycane would therefore be complementary to soydiesel in the United States.

The Röse-Gottlieb method is one of the most widely used methods for extracting lipids from milk samples. However, we found that lipid recovery from liquid infant formula and human breast milk was lower than expected. Better lipid recovery from these liquid matrices was obtained by solid phase extraction using silica gel; ~10% more could be recovered from liquid infant formula and ruminant milk, and 25% more from human breast milk. However, the method is not recommended for lipid extraction from dried whole milk powders.

The energy sector faces significant challenges globally, including increasing air pollution, rising energy demands, and fluctuating crude oil prices. In response, researchers have turned their attention to third-generation biofuels derived from algae due to their numerous advantages over first (crop-based) and second-generation (petro crop-based) biofuels. Microalgae offer faster growth rates, shorter regeneration times, the potential to utilize waste lands for cultivation, and scalability. However, challenges such as maintaining biomass yield while increasing lipid synthesis persist. To address this challenge, researchers are employing metabolomic strategies to target the lipid production pathway in microalgae. This review provides a comprehensive overview of various metabolomic approaches, including gene editing techniques such as CRISPR-Cas9, RNA interference (RNAi), zinc finger nucleases (ZFN), and transcription activator-like effector nucleases (TALENs), aimed at enhancing lipid synthesis while maintaining biomass yield in microalgae. Additionally, the review discusses major challenges and the future potential of microalgal-based biofuels. • Comprehensive reviews of several research on the generation of biofuel from microalgae algae are included. • oThe best methods for producing biofuel from microalgae are reviewed. • oFuture potential and current issues with producing biofuel from microalgae algae are discussed. [ABSTRACT FROM AUTHOR]

Diacylglycerol acyltransferase (DGAT) is a crucial enzyme involved in triacylglycerol (TAG) accumulation. To investigate the regulation of DGAT genes in the mesocarp of oil palm, a key transcription factor, EgbHLH63, was identified by a yeast one-hybrid assay. The interaction between EgbHLH63 and the EgDGAT1 promoter (proEgDGAT1) and its potential role in TAG synthesis were investigated. Binding of EgbHLH63 to proEgDGAT1 was confirmed by dual-luciferase reporter gene assays and EMSA in vitro. Overexpression of EgbHLH63 in oil palm protoplasts resulted in a significant reduction in EgDGAT1 expression. Silence of EgbHLH63 in transgenic embryoids restored high levels of EgDGAT1 expression and significantly increased TAG content. In addition, two other transcription factors, EgULT1 and EgZFP, were identified as interacting with EgbHLH63. They recognized B-box and AT-rich motifs in the EgDGAT1 promoter, respectively. These two transcription factors also negatively regulated EgDGAT1 expression, thereby affecting oil accumulation. Collectively, the results shed light on the lipid mechanism pathway involving EgDGAT1 in the mesocarp and offer promising research avenues for improving oil yield and quality in oil palm. • EgbHLH63, a bHLH-like transcription factor, regulates EgDGAT1 in oil palm mesocarp. • EgbHLH63 overexpression reduces EgDGAT1, while silencing boosts TAG content. • EgULT1 and EgZFP interact with EgbHLH63, impacting EgDGAT1 expression. • Insights into the EgDGAT1 lipid mechanism pathway in oil palm mesocarp are revealed. [ABSTRACT FROM AUTHOR]

Anisotropic gold nanoparticles have been recognized as promising agents for medical diagnostics and cancer therapy due to their wide functionality, photothermal effect, and ability for optical signal amplification in the near-infrared range. In this work, a simple and rapid method for the preparation of bone-shaped gold nanoparticles coated with a dye-impregnated silica shell with an aminated surface is proposed. The possibility of further functionalization the nanostructures with a delivery vector using folic acid as an example is demonstrated. The average size of the resulting tags does not exceed 70 nm, meeting the criteria of cell endocytosis. The prepared tags exhibit surface-enhanced Raman scattering (SERS) spectra at excitation with lasers of 632.8 and 785 nm. Cell imaging is performed on HeLa cells based on the most pronounced SERS bands as a tracking signal. The obtained images, along with scanning electron microscopy of cell samples, revealed the tendency of tags to agglomerate during endocytosis followed by the “hot spots” effect. To evaluate the toxic and proliferative effect of the nanotags, an MTT assay was performed with two HeLa and HEP G2 cell lines. The results revealed higher viability for HEP G2 cells.

The association between a dietary pattern characterised by high alcohol intake and dyslipidaemia has not been fully investigated. Therefore, the present study aimed to investigate the association between alcohol dietary patterns and the prevalence of dyslipidaemia and its components. This cross-sectional study enrolled 2171 men and women aged ≥40 years who were alumni of a Japanese university. To identify dietary patterns, a principal component analysis was performed based on the energy-adjusted food intake estimated by a brief-type self-administered diet history questionnaire. Three dietary patterns were identified, the second of which was named the alcohol dietary pattern and was characterised by a high intake of alcoholic beverages, liver, chicken and fish. This alcohol dietary pattern was associated with reduced LDL-cholesterol levels. The fully adjusted OR (95 % CI) of high LDL-cholesterol for the lowest through highest quartile of alcohol dietary pattern score were 1·00 (reference), 0·83 (0·64, 1·08), 0·84 (0·64, 1·10) and 0·68 (0·49, 0·94), respectively. Subgroup analysis showed that the alcohol dietary pattern was inversely associated with the prevalence of dyslipidaemia in women, whereas it was positively associated with high TAG levels in men. In conclusion, the alcohol dietary pattern, characterised by a high intake of alcoholic beverages, liver, chicken and fish, was associated with the prevalence of dyslipidaemia and its components. This finding provides useful information for the prevention and treatment of dyslipidaemia by modifying the diet. [ABSTRACT FROM AUTHOR]

Recommender systems are popular tools used in many applications, such as e-commerce, e-learning, and social networks to help users select their desired items. Collaborative filtering is a widely used recommendation technique that employs previous ratings of users to predict their future interests. Lack of sufficient ratings often reduces the performance of collaborative filtering recommendation methods. Additional side resources, such as trust relationships and tag information can be employed to enhance the recommendation accuracy. However, trust and tag data are often heavily sparse as users mainly provide insufficient information about these side resources. Moreover, such additional resources have generally large dimensions which result in increasing the computational complexity of recommendation models in calculating similarity values. To cope with these problems, a new recommendation model is proposed that utilizes deep neural networks to model the representation of trust relationships and tag information. To this end, a sparse autoencoder is used to extract latent features from user-user trust relationships and user-tag matrices. Then, the extracted latent features are utilized to calculate similarity values between users, which are then used to form the nearest neighbors of the target user and predict unseen items. The proposed method can tackle the data sparsity problem and reduce the computational complexity of recommender systems as the extracted latent features have smaller dimensions in comparison to the original data. Experimental results on two benchmark datasets reveal the effectiveness of the proposed method and show its outperformance over state-of-the-art recommender systems. [ABSTRACT FROM AUTHOR]

The article discusses the effect of honey on lipid profiles.

The distribution of teletreatment carried out by psychologists during the COVID-19 pandemic for GAD, specific phobia, agoraphobia, social anxiety, panic, OCD and PTSD, and whether experience in teletherapy has an significant effect on demand have not been studied. The results indicate that GAD with 69.2% has been the disorder that has received the most teletherapy and phobia with 60.5%, the least. Panic, social anxiety, PTSD, OCD, and agoraphobia had a demand of 67.2%, 66.8%, 64.0%, 63.5%, and 62.2%, respectively. The experience in teletherapy was significant. Tele-treatment for experienced psychologists increased an average of 93.9% compared to 35.7% for those without experience. 22.8% of psychologists did not carry out anxiety teletherapy. These results may be useful to develop specific prevention and telematic intervention programs for anxiety disorders in the face of future coronavirus pandemics. [ABSTRACT FROM AUTHOR]

Copyright of Issues in Ethnology Anthropology is the property of Issues in Ethnology Anthropology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Dealing with the unstable (virtual) realities that are repeatedly constructed in the film Tag (2015), Sion Sono explores entirely new forms of amusement in the realm of transhumanism. In the following text, I will discuss the concept of ressentiment in light of a master-slave relationship between the gamer/fan and an objectified game character, meant to entertain the transhuman subject. From the perspective of critical theory, the film is further examined as a disturbing reflection of the gender issues in both Japanese and global media environments, but read in contrast to the prevalent opinion of those critics who perceive it as misogynistic. [ABSTRACT FROM AUTHOR]

A single high-fat, high-carbohydrate meal (HFHC) results in elevated postprandial glucose (GLU), triglycerides (TAG) and metabolic load index (MLI; TAG (mg/dl) + GLU (mg/dl)) that contributes to chronic disease risk. While disease risk is higher in older adults (OA) compared to younger adults (YA), the acute effects of exercise on these outcomes in OA is understudied. Twelve YA (age 23.3 ± 3.9 yrs, n = 5 M/7 F) and 12 OA (age 67·7 ± 6.0 yrs, n = 8 M/4 F) visited the laboratory in random order to complete a HFHC with no exercise (NE) or acute exercise (EX) condition. EX was performed 12 hours prior to HFHC at an intensity of 65 % of maximal heart rate to expend 75 % of the kcals consumed in HFHC (Marie Callender's Chocolate Satin Pie; 12 kcal/kgbw; 57 % fat, 37 % CHO). Blood samples were taken at 0, 30, 60, 90 minutes, and then every hour until 6 hours post-meal. TAG levels increased to a larger magnitude in OA (Δ∼61 ± 31 %) compared to YA (Δ∼37 ± 34 %, P < 0·001), which were attenuated in EX compared to NE (P < 0·05) independent of age. There was no difference in GLU between OA and YA after the HFM, however, EX had attenuated GLU independent of age (NE: Δ∼21 ± 26 %; EX: Δ∼12 ± 18 %, P = 0·027). MLI was significantly lower after EX compared to NE in OA and YA (P < 0·001). Pre-prandial EX reduced TAG, GLU and MLI post-HFHC independent of age. [ABSTRACT FROM AUTHOR]

We suggest improving minimally-invasive stenosis severity estimation, using a combination of existing geometry-based methods with Transluminal Attenuation Gradient measurements. Instead of local flow values, the method uses flow distribution ratios along the entire tree. The tree geometry is used to derive a lumped model and predict the 'theoretical' ratios in each bifurcation, while attenuation measurements are used for extracting 'actual' ratios. The discrepancies between the measured and the theoretical values are utilized to assess a functional degree of stenosis. Our experimental and numerical analyses show that the quantitative value of discrepancy is proportional to stenosis severity, regardless of boundary conditions. [ABSTRACT FROM AUTHOR]

Objective: The purpose of this paper was to investigate the rate of keywords overlapping in the articles with Bibsonomy labels and accepted descriptors in the Library of Congress Subject Headings (LCSH) in the Scientometrics journals. Methodology: This paper was an applied study based on investigating of overlapping keywords in the articles. The research method is an observational content analysis. The data gathering tool was a researcher-made checklist. In this study, 500 keywords were collected from the published papers from 2017 to December of 2018 as population data (new article keywords) regardless of thematic categorization. It was only aimed to collect the keywords from a specialized source in scientometrics field then entered them into Excel software. So, 50 keywords with more than 1000 frequency on the all three Scientometrics sites were selected as a sample. The samples were surveyed from the point of, frequency of subscriptions with the bibsonomy social site and various dimensions of LCSH. Finally, the results were obtained for analyzing data by the use of descriptive statistics (with the criterion of availability in the sites of the research questions), the percentage of subscription frequency and inferential statistics (non-parametric test and Spearman's correlation). The SPSS software was also utilized. Findings: The 500 extracted keywords from Scientometrics articles were ordered from top to bottom in Excel, and then 50 keywords with high frequency were obtained from the point of availability and frequency in bibsonomy and LCSH, and finally the percentage of their commonalities was obtained. The results showed that there is an 82 percent overlap between the social labels of the Bibsonomy site and the descriptive headings of the LCSH which are related to the same labels. Also، there was a 28 percent overlap between the keywords of scientometrics articles in the Scientometrics Journal and the descriptive headings of the LCSH, with the same related keywords. Conclusion: The authors did not agree on the choice of keywords in their articles with tags on Bibsonomy and on the LCSH, and the least similarities are also not based on the specific rules. Therefore، it would be better for the authors to use a specific standard in choosing keywords، such as: the topic title of the Congress. In fact, the present study found that the authors made no reference to the LCSH. But, the idea of labeling users on the Bibsonomy site was closer to that of the Congressional Topical Indicators. So, the authors will improve the access to their article by the choice of keywords by the tags of both ranking sites such as Bibsonomy and descriptors of the LCSH. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Fuzhou University is the property of Journal of Fuzhou University, Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

This article discusses hashtags, which – being a type of free social nomination – reflect and identify the sense of ethnic stereotypes. The aim of the analysis is two-directional and concerns, firstly, tags as the route of the social transition of stereotype knowledge in the communicative space of the service wykop.pl. Secondly, the analysis shows changes in the established enemy image in the index #rosja. As context and statistical analysis show, the tag #rosja is a focal category, which grasps additional operators establishing the stereotype of Russia and Russians as enemy/enemies and filling it in with actual senses and concepts. [ABSTRACT FROM AUTHOR]

Abstract Background Nitrogen (N) starvation in algae induces a variety of structural and metabolic changes including accumulation of triacylglycerol (TAG). Given the promising prospect of using algae as feedstock for biofuel production, accumulation of TAG upon N starvation becomes an ideal system to study TAG biosynthesis. Under nitrogen-depleted conditions, algae also accumulate compatible solutes such as sugar and certain amino acids, which is expected to elevate osmolarity in the cytoplasm. However, how osmoregulation is maintained and how it impacts on carbon metabolism, especially TAG accumulation under N starvation, are not well understood. Results We show here that potassium channel KCN11 localized in the contractile vacuole (CV) mediates osmoregulation during N starvation and loss of KCN11 profoundly affects cell physiology and TAG biosynthesis. KCN11 level is increased and the CV pulsation is accelerated. Loss of KCN11 induces aberrant CV cycle, inhibition of cell growth, increase of cell size, inhibition of chlorophyll loss and TAG accumulation. These effects are rescued by addition of sucrose to raise osmolarity in the culture medium, indicating that osmoregulation is required for cell adaptation to N starvation. Metabolomic analysis shows reduction of acetyl-CoA and accumulation of glyceraldehyde-3-phosphate in kcn11 mutant relative to the control under N starvation, indicating that defects in acetyl-CoA biosynthesis and some metabolic steps from glyceraldehyde-3-phosphate to TAG contribute to the decreased TAG accumulation due to loss of osmoregulation. Conclusions This work provides novel insight of osmoregulation during N starvation in the control of cell physiology and metabolism especially TAG accumulation. According to these findings, we propose that osmolarity should be carefully monitored during the industrial production of biodiesel.

The aim of the present study was to examine whether serum Zn concentrations were associated with metabolic risk factors in Chinese children and adolescents. This was a cross-sectional study including 3241 participants, aged 6 to 17 years, from Jiangsu, China. Metabolic risk factors included fasting glucose (FG), total cholesterol (TC), TAG, HDL-cholesterol, LDL-cholesterol, systolic blood pressure and diastolic blood pressure. Data were analysed using multi-variable linear regression and generalised additive models, which were adjusted for age, sex, high-sensitive C-reactive protein, estimated glomerular filtration rate, BMI and region of residence, to assess the associations of serum Zn concentrations with metabolic risk factors. We observed a negative association between serum Zn concentrations and FG (coefficient = −0·532; 95 % CI −0·569, −0·495; P < 0·001). Moreover, TC (coefficient = 0·175; 95 % CI 0·127, 0·222; P < 0·001), HDL-cholesterol (coefficient = 0·137; 95 % CI 0·082, 0·193; P < 0·001) and LDL-cholesterol (coefficient = 0·195; 95 % CI 0·128, 0·263; P < 0·001) were found to be positively associated with Zn levels. A generalised additive model showed that the negative association between serum Zn and FG was weak at lower serum Zn concentrations and was stronger with the increase in serum Zn concentrations. Additionally, a U-shaped association between serum Zn and TAG was observed. Serum Zn concentrations were associated with FG, TC, TAG, HDL-cholesterol and LDL-cholesterol levels in Chinese children and adolescents. Lower levels of serum Zn were more likely related to a poor metabolic status. [ABSTRACT FROM AUTHOR]

A new system to record growth data for fruit vegetables has been developed. Nodes of crop plants are tagged with a QR code, allowing researchers to record growth events using a tablet PC. Growth data are stored in a database, and tagged with the date and time. As an implementation case, differences in growth of cucumber caused by carbon dioxide gas and mist application were recorded by using the new system. The system allowed acquisition of in-depth data (such as the location where a fruit was harvested, the number of days from bloom to harvesting, and the number of flowers that did not produce fruit) which were previously difficult to acquire, as well as the yield per plant, facilitating analysis. The new system also made it possible to illustrate the growth of individual crop plants, from planting to harvest, as an animation. [ABSTRACT FROM AUTHOR]

RFID systems are one of the essential technologies and used many diverse applications. The security and privacy are the primary concern in RFID systems which are overcome by using suitable authentication protocols. In this manuscript, the costeffective RFID-Mutual Authentication (MA) using a lightweight Extended Tiny encryption algorithm (XTEA) is designed to overcome the security and privacy issues on Hardware Platform. The proposed design provides two levels of security, which includes secured Tag identification and mutual authentication. The RFIDMA mainly has Reader and Tag along with the backend Server. It establishes the secured authentication between Tag and Reader using XTEA. The XTEA with Cipher block chaining (CBC) is incorporated in RFID for secured MA purposes. The authentication process completed based on the challenge and response between Reader and Tag using XTEA-CBC. The present work is designed using Verilog-HDL on the Xilinx environment and implemented on Artix-7 FPGA. The simulation and synthesis results discussed with hardware constraints like Area, power, and time. The present work is compared with existing similar approaches with hardware constraints improvements. [ABSTRACT FROM AUTHOR]

There are few data on the effects on TAG, glucose and uric acid of chronic consumption of a moderate dose of fructose in solid foods. Twenty-eight participants with prediabetes and/or obesity and overweight commenced the study (BMI 32·3 kg/m2, age 44·7 years, fasting glucose 5·3 (sd 0·89) mmol/l and 2-h glucose 6·6 (sd 1·8) mmol/l). Twenty-four men and women who completed the study consumed, in random order, two acute test meals of muffins sweetened with either fructose or sucrose. This was followed by 4-week chronic consumption of 42 g/d of either fructose or sucrose in low-fat muffins after which the two meal tests were repeated. The sugar type in the chronic feeding period was also randomised. Fasting TAG increased after chronic consumption of fructose by 0·31 (sd 0·37) mmol/l compared with sucrose in those participants with impaired fasting glucose (IFG)/impaired glucose tolerance (IGT) (P = 0·004). Total cholesterol (0·33 mmol/l), LDL-cholesterol (0·24 mmol/l) and HDL-cholesterol (0·08 mmol/l) increased significantly over the 1- month feeding period with no differences between muffin types. Fasting glucose was not different after 1 month of muffin consumption. Uric acid response was not different between the two sugar types either baseline or 1 month, and there were no differences between baseline and 1 month. The increase in fasting TAG in participants with IFG/IGT suggests the need for caution in people at increased risk of type 2 diabetes. [ABSTRACT FROM AUTHOR]

High feedstock cost and low oil yields per unit of land from temperate oilseed crops limit the growth of commercial‐scale biodiesel production. Recently, highly productive crops, such as sugarcane and energycane, have been engineered to accumulate triacylglycerides (TAGs) that allow the production of far more industrial vegetable oil than previously possible. A proof‐of‐concept suggests that biodiesel production from engineered energycane will be possible. However, before making efforts for scale‐up, it is critical to understand the commercial feasibility and economic competitiveness of this process. This study performs techno‐economic analysis of a unique biorefinery processing energycane to co‐produce biodiesel and ethanol. Comprehensive process simulation models were developed for two scenarios: (i) biodiesel from TAGs and ethanol from fermentation of sugars in juice and (ii) biodiesel from TAGs and ethanol from fermentation of sugars in juice and hydrolysis of carbohydrates in bagasse. Based on the target levels, the analysis was performed for energycane containing 0%, 5%, and 7.7% TAGs (d.b.). The biodiesel from engineered energycane was found economically viable and competitive to soybean biodiesel. Although the capital investment is higher compared to the soybean biodiesel plant, the biodiesel production costs ($0.66–$0.9/L) were lower than soybean biodiesel ($0.91/L). Biorefinery‐scenario‐1 processing energycane containing 7.7% TAG produces biodiesel with profitability (IRR 7.84) slightly lower than soybean biodiesel (IRR 8.3), but yields five times of biodiesel per unit land and is self‐sustainable for energy requirements. The surplus electricity can displace fossil electricity and provide environmental benefits. Monte Carlo simulation indicated that biorefinery is profitable with a 29%–65% probability (NPV > 0) which is largely controlled by feedstock composition and biodiesel market price. It is important to note that energycane can be grown on the marginal rainfed lands in S.E. USA, where soybean would not be viable. Biodiesel from engineered energycane would therefore be complementary to soydiesel in the United States. [ABSTRACT FROM AUTHOR]

Peanut (Arachis hypogaea L.) is one of the important oil crops worldwide. Revealing the molecular basis of seed oil synthesis and analyzing key candidate genes may have important implications for enhancing peanut production. In this study, we investigated the dynamic changes in the oil accumulation rate and gene expression levels in developing peanut seeds. A Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analysis revealed that the up-regulated differentially expressed genes (DEGs) among three varieties at 25–35 days after flowering (DAF) were involved in fatty acid synthesis, carbon metabolism, and pyruvate metabolism. Between 25 and 35 DAF, the up-regulated DEGs in the high-oil varieties, but not in the low-oil variety, were related to acetyl-CoA synthesis. We examined the differences in the varieties at the same stages. We analyzed the lipid metabolism-related genes by protein–protein interaction (PPI), and finally identified 57 DEGs that may influence the peanut oil content. These candidate genes included three genes encoding acetyl-CoA carboxylase (ACCase), one gene encoding ketoacyl-ACP synthase III (KASIII), one gene encoding hydroxyacyl-ACP dehydrase (HAD), and one gene encoding enoyl-ACP reductase (EAR), which form the Type II fatty acid synthase complex. Additionally, we also found that 11 transcription factors may affect oil content. These identified candidate genes may help to further clarify the molecular basis of the oil accumulation in peanut seeds. [ABSTRACT FROM AUTHOR]

To produce a web services clustering with values that satisfy many requirements is a challenging focus. In this article, the authors proposed a new approach with two models, which are helpful to the service clustering problem. Firstly, a document-tag LDA model (DTag-LDA) is proposed that considers the tag information of web services, and the tag can describe the effective information of documents accurately. Based on the first model, this article further proposes an efficient document weight and tag weight-LDA model (DTw-LDA), which fused multi-modal data network. To further improve the clustering accuracy, the model constructs the network for describing text and tag respectively and then merges the two networks to generate web service network clustered. In addition, this article also designs experiments to verify that the used auxiliary information can help to extract more accurate semantics by conducting service classification. And the proposed method has obvious advantages in precision, recall, purity, and other performance. [ABSTRACT FROM AUTHOR]

With the emerging of the massive Machine Type Communication usage scenario, the legacy Random Access (RA) procedures need to be fully renewed to meet the huge number of accesses and the energy-constrained device requirements. In this context, the strategy of transmitting tagged preambles as access requests is gaining importance. In fact, it can reduce the number of signaling transmissions per access attempt, the overall number of phases in the access procedure, and, accordingly, energy consumption per device. However, the effectiveness of detection strategies of tagged preambles by the gNB receiver plays a fundamental role on the RA procedure performance. Up to now, the performance of these advanced detection procedures has been obtained only by running a large number of simulations that are typically highly time-consuming. To the best of our knowledge, this paper presents the first analytical model to analyze the correct detection of both the preamble and the tag transmitted by each device in the presence of interference, due to other preambles and tags, and of noise. The high accuracy of the proposed model is verified through simulations. In addition, we show how our analytical study can be a good tool to investigate and derive innovative detection strategies. [ABSTRACT FROM AUTHOR]

Generalized Anxiety Disorder (GAD) is frequently chronic, considerable prevalence, high comorbidity, significant costs for the patients, its family, the health system, and poor response to existing treatments. Given the importance of the clinical problem, it is considered necessary to bring clinicians and researchers to the current perspectives on it. With that aim, the main characteristics of the following cognitive behavioral models are presented for their understanding and therapeutic approach: worry as avoidance model, emotion dysregulation model, acceptance-based behavioral therapy, intolerance of uncertainty’s model, metacognitive model, contrast avoidance model and the cognitive model. Their similarities and differences are briefly compared and discussed, and the need for collaborative development of psychopathological models of understanding as well as clinical strategies and tools to alleviate the suffering of affected people is concluded.

In this paper, we consider the problem of routing interruption, which has received significant interest in recent years. To solve this problem, rerouting is an effective way. However, how to design an effective secure and applicable rerouting algorithm remains a significant challenge. To this end, we propose a fast rerouting framework for routing interruption. Our framework consists of two parts: (1) Diagnose routing interruption. We determine the location of interruption by directly interrogating the control plane IPv6 stack. (2) Implement fast rerouting. We propose the rerouting algorithm to make the router match and reroute all prefixes affected by interruptions. This paper updates the path only by adding a forwarding rule, thus the interruption recovery time is reduced. We conduct a comprehensive evaluation for our rerouting framework. Experimental results show that our method is better than FCP, OSPF and DLF in speed and accuracy.