Search

Your search keyword '"Stefan, Hermann"' showing total 889 results
Start Over Author "Stefan, Hermann"
889 results on '"Stefan, Hermann"'

110. Preface

Author

Stefan, Hermann, primary and Theodore, William H., additional

Published
2012
Full Text
View/download PDF

113. Standardized Computer-based Organized Reporting of EEG: SCORE

Author

Beniczky, Sándor, Aurlien, Harald, Brgger, Jan C., Fuglsang-Frederiksen, Anders, Martins-da-Silva, António, Trinka, Eugen, Visser, Gerhard, Rubboli, Guido, Hjalgrim, Helle, Stefan, Hermann, Rosén, Ingmar, Zarubova, Jana, Dobesberger, Judith, Alving, Jrgen, Andersen, Kjeld V., Fabricius, Martin, Atkins, Mary D., Neufeld, Miri, Plouin, Perrine, Marusic, Petr, Pressler, Ronit, Mameniskiene, Ruta, Hopfengärtner, Rüdiger, van Emde Boas, Walter, and Wolf, Peter

Published
2013
Full Text
View/download PDF

133. The delta between postoperative seizure freedom and persistence: Automatically detected focal slow waves after epilepsy surgery

Author

Schönherr, Margit, Stefan, Hermann, Hamer, Hajo M., Rössler, Karl, Buchfelder, Michael, and Rampp, Stefan

Subjects
Adult, Male, Adolescent, lcsh:Computer applications to medicine. Medical informatics, Delta activity, lcsh:RC346-429, Young Adult, Medizinische Fakultät, Recurrence, Seizures, Humans, ddc:610, Postoperative Period, lcsh:Neurology. Diseases of the nervous system, Epilepsy, Magnetoencephalography, Regular Article, Middle Aged, Delta Rhythm, lcsh:R858-859.7, Surgery, Female, Electrocorticography, Persisting seizures, Follow-Up Studies
Abstract

Objective In this study, we use a novel automated method for localization and quantitative comparison of magnetoencephalographic (MEG) delta activity in patients with and without recurrent seizures after epilepsy surgery as well as healthy controls. Methods We identified the generators of delta activity by source location in frequency domain between 1 and 4 Hz in spontaneous MEG data. Comparison with healthy control subjects by z-transform emphasized relative changes of activation in patients. The individual results were compared to spike localizations and statistical group analysis was performed. Additionally, MEG results were compared to 1–4 Hz activity in invasive EEG (iEEG) in two patients, in whom this data was available. Results Patients with recurrent seizures exhibited significantly increased focal MEG delta activity both in comparison to healthy controls and seizure free patients. This slow activity showed a correlation to interictal epileptic activity and was not explained by consequences of the resection alone. In two patients with iEEG, iEEG analysis was concordant with the MEG findings. Significance The quantity of delta activity could be used as a diagnostic marker for recurrent seizures. The close relation to epileptic spike localizations and the resection volume of patients with successful second surgery imply involvement in seizure recurrence. This initial evidence suggests a potential application in the planning of second epilepsy surgery., Highlights • We introduce a novel automated method for localization and quantitative comparison of delta activity in epilepsy patients. • Comparison with healthy controls shows significantly increased slow waves in patients with and without recurring seizures. • Significant correlation of delta and interictal epileptic activity could not be explained by the resection alone. • Relation to spike localizations and resection volume imply involvement in seizure recurrence. • The quantity of delta activity could be used as a diagnostic marker for recurrent seizures.

Published
2016

Catalog

Books, media, physical & digital resources
See catalog results