143 results on '"Shrader, M Wade"'
Search Results
102. Collaborations with Pediatric Hospitalists: National Surveys of Pediatric Surgeons and Orthopedic Surgeons
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Rosenberg, Rebecca E., primary, Abzug, Joshua M., additional, Rappaport, David I., additional, Mazziotti, Mark V., additional, Shrader, M. Wade, additional, Zipes, David, additional, Nwomeh, Benedict, additional, and McLeod, Lisa, additional
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- 2018
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103. Where are we Walking? An Introduction to a JPOSNA Year-Long Series on Gait Analysis in Pediatric Orthopaedics
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Shrader, M. Wade
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- 2020
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104. Characteristics of Medical Professional Liability Claims in Pediatric Orthopaedics
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Burns, Jessica, primary, Belthur, Mohan V., additional, Irby, Steven, additional, Boan, Carla, additional, and Shrader, M. Wade, additional
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- 2017
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105. Orthopedic surgical outcomes that matter in children with cerebral palsy.
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Shrader, M. Wade
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CHILDREN with cerebral palsy , *PEDIATRIC orthopedics - Abstract
This commentary is on the original article by Almoajil et al. on pages 254–263 of this issue. [ABSTRACT FROM AUTHOR]
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- 2023
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106. Characteristics of Medical Professional Liability Claims in Pediatric Orthopaedics
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Burns, Jessica, primary, Belthur, Mohan V., additional, Irby, Steven, additional, Boan, Carla, additional, and Shrader, M. Wade, additional
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- 2016
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107. Back pain in Duchenne muscular dystrophy
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Segal, Lee S., primary, Odgers, Ryan, additional, Carpentieri, David, additional, and Shrader, M. Wade, additional
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- 2016
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108. Evaluation of Patient Satisfaction Surveys in Pediatric Orthopaedics
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Segal, Lee S., primary, Plantikow, Carla, additional, Hall, Randon, additional, Wilson, Kristina, additional, and Shrader, M. Wade, additional
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- 2015
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109. Evaluation of Dexmedetomidine and Postoperative Pain Management in Patients With Adolescent Idiopathic Scoliosis
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Jones, John S., primary, Cotugno, Richard E., additional, Singhal, Neil Raj, additional, Soares, Neha, additional, Semenova, Janet, additional, Nebar, Sean, additional, Parke, Emily J., additional, Shrader, M. Wade, additional, and Hotz, Jeffrey, additional
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- 2014
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110. Diagnosis and Initial Management of Musculoskeletal Coccidioidomycosis in Children
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Ho, Aaron K., primary, Shrader, M. Wade, additional, Falk, Miranda N., additional, and Segal, Lee S., additional
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- 2014
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111. Spine Radiographs for Neuromuscular Scoliosis
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Segal, Lee S., primary, Shrader, M. Wade, additional, and Schwentker, Edwards P., additional
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- 2012
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112. Improving Initial Acetabular Component Stability in Revision Total Hip Arthroplasty
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Jacofsky, David J., primary, McCamley, John D., additional, Jaczynski, Andrew M., additional, Shrader, M. Wade, additional, and Jacofsky, Marc C., additional
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- 2012
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113. Suspected Nonaccidental Trauma and Femoral Shaft Fractures in Children
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Shrader, M. Wade, primary, Bernat, Nicholas M., additional, and Segal, Lee S., additional
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- 2011
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114. Biomechanical Strength of the Peri-Loc® Proximal Tibial Plate: A Comparison of All-Locked Versus Hybrid Locked/Nonlocked Screw Configurations
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Estes, Chris, primary, Rhee, Peter, additional, Shrader, M Wade, additional, Csavina, Kristine, additional, Jacofsky, Marc C, additional, and Jacofsky, David J, additional
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- 2008
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115. Femoral Neck Fractures in Pediatric Patients
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Shrader, M Wade, primary, Jacofsky, David J, additional, Stans, Anthony A, additional, Shaughnessy, William J, additional, and Haidukewych, George J, additional
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- 2007
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116. Surgical dislocation with trochanteric osteotomy: a surgical approach for femoroacetabular impingement
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Shrader, M Wade, primary and Sucato, Daniel J, additional
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- 2005
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117. Effects of Knee Pain Relief in Osteoarthritis on Gait and Stair-Stepping
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Shrader, M Wade, primary, Draganich, Louis F, additional, Pottenger, Lawrence A, additional, and Piotrowski, Gary A, additional
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- 2004
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118. Insall Award Paper: Primary TKA in Patients With Lymphedema
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Shrader, M. Wade, primary and Morrey, Bernard F., additional
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- 2003
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119. Targeted Physical Therapy Combined with Spasticity Management Changes Motor Development Trajectory for a 2-Year-Old with Cerebral Palsy.
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Stuyvenberg, Corri L., Brown, Shaaron E., Inamdar, Ketaki, Evans, Megan, Hsu, Lin-ya, Rolin, Olivier, Harbourne, Regina T., Westcott McCoy, Sarah, Lobo, Michele A., Koziol, Natalie A., Dusing, Stacey C., and Shrader, M. Wade
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MOTOR ability ,CEREBRAL palsy ,PHYSICAL therapy ,CHILDREN with cerebral palsy ,GROSS motor ability - Abstract
Therapies for children with cerebral palsy (CP) often fail to address essential components of early rehabilitation: intensity, child initiation, and an embodied approach. Sitting Together And Reaching To Play (START-Play) addresses these issues while incorporating intensive family involvement to maximize therapeutic dosage. While START-Play was developed and tested on children aged 7–16 months with motor delays, the theoretical construct can be applied to intervention in children of broader ages and skills levels. This study quantifies the impact of a broader START-Play intervention combined with Botulinum toxin-A (BoNT-A) and phenol on the developmental trajectory of a 24 month-old child with bilateral spastic CP. In this AB +1 study, A consisted of multiple baseline assessments with the Gross Motor Function Measure-66 and the Assessment of Problem Solving in Play. The research participant demonstrated a stable baseline during A and changes in response to the combination of BoNT-A/phenol and 12 START-Play sessions during B, surpassing the minimal clinically important difference on the Gross Motor Function Measure-66. The follow-up data point (+1) was completed after a second round of BoNT-A/phenol injections. While the findings suggest the participant improved his gross motor skills with BoNT-A/phenol and START-Play, further research is needed to generalize these findings. [ABSTRACT FROM AUTHOR]
- Published
- 2021
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120. Accuracy of Emergency Room Physicians' Interpretation of Elbow Fractures in Children.
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Shrader, M. Wade, Campbell, Mark D., and Jacofsky, David J.
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Elbow fractures in children can be difficult diagnoses for inexperienced physicians to make. The purpose of this prospective study was to determine the accuracy of radiograph interpretation of elbow fractures in children by emergency room (ER) physicians. Thirty fractures were analyzed. The ER physician's radiograph interpretation was compared to the final interpretation by the treating staff pédiatrie orthopedic surgeon. Accuracy rates were determined for overall agreement and by fracture subtype. Overall accuracy of ER physicians' interpretation was 53% (16/30). This study underscores the importance of educating ER physicians and residents in children's fracture interpretation to optimize patient outcomes. Orthopedists need to be vigilant when taking care of these patients to prevent unnecessary complications. [ABSTRACT FROM AUTHOR]
- Published
- 2008
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121. Anterior distal femoral hemiepiphysiodesis in children with cerebral palsy: Establishing surgical indications and techniques using the modified Delphi method and literature review.
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Shore, Benjamin J., McCarthy, James, Shrader, M. Wade, Graham, H. Kerr, Veerkamp, Matthew, Rutz, Erich, Chambers, Henry, Davids, Jon R., Narayanan, Unni, Novacheck, Tom F., Pierz, Kristan, Dreher, Thomas, Rhodes, Jason, Shilt, Jeffery, Theologis, Tim, Van Campenhout, Anja, and Kay, Robert M.
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CHILDREN with cerebral palsy , *SURGICAL indications , *DELPHI method , *OPERATIVE surgery , *CONTRACTURE (Pathology) , *LITERATURE reviews - Abstract
Purpose: The purpose of this study was to develop consensus for the surgical indications of anterior distal femur hemiepiphysiodesis in children with cerebral palsy using expert surgeon opinion through a modified Delphi technique. Methods: The panel used a 5-level Likert-type scale to record agreement or disagreement with 27 statements regarding anterior distal femur hemiepiphysiodesis. Consensus was defined as at least 80% of responses being in the highest or lowest 2 of the Likert-type ratings. General agreement was defined as 60%–79% falling into the highest or lowest 2 ratings. Results: For anterior distal femur hemiepiphysiodesis, 27 statements were surveyed: consensus or general agreement among the panelists was achieved for 22 of 27 statements (22/27, 82%) and 5 statements had no agreement (5/27, 18%). There was general consensus that anterior distal femur hemiepiphysiodesis is indicated for ambulatory children with cerebral palsy, with at least 2years growth remaining, and smaller (<30degrees) knee flexion contractures and for minimally ambulatory children to aid in standing/transfers. Consensus was achieved regarding the importance of close radiographic follow-up after screw insertion to identify or prevent secondary deformity. There was general agreement that percutaneous screws are preferred over anterior plates due to the pain and irritation associated with plates. Finally, it was agreed that anterior distal femur hemiepiphysiodesis was not indicated in the absence of a knee flexion contracture. Conclusion: Anterior distal femur hemiepiphysiodesis can be used to treat fixed knee flexion contractures in the setting of crouch gait, but other associated lever arm dysfunctions must be addressed by single-event multilevel surgery. [ABSTRACT FROM AUTHOR]
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- 2022
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122. Prevalence and Treatment of Surgical Complications Following Proximal Femoral Osteotomies in Children with Cerebral Palsy: An Analysis of 1085 Hips.
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Imerci, Ahmet, Miller, Freeman, Howard, Jason J., and Shrader, M. Wade
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RISK assessment , *HIP surgery , *COMPLICATIONS of prosthesis , *MULTIPLE regression analysis , *CEREBRAL palsy , *RETROSPECTIVE studies , *MULTIVARIATE analysis , *INFECTION , *SURGICAL complications , *OSTEOTOMY , *LONGITUDINAL method , *METAPLASTIC ossification , *BONE fractures , *MEDICAL records , *ACQUISITION of data , *DYSTONIA , *PATIENT aftercare , *DISEASE risk factors , *DISEASE complications , *CHILDREN - Abstract
Purpose: Proximal femoral osteotomy (PFO) is a reconstructive surgical option used to improve hip containment or correct internal hip rotation gait in children with cerebral palsy (CP). A few reports describe the risk of surgical complications after PFO. The purpose of this study was to determine the risk factors associated with adverse postoperative surgical outcomes in pediatric patients with CP following PFO and to report the treatment of complications. Methods: Following institutional review board approval, 1085 (1003 primary and 82 secondary) PFO procedures were retrospectively reviewed in 563 children with CP with at least 1 year of follow-up after final surgery over an 18-year follow-up period. Demographic characteristics, motor type, gross motor function classification system (GMFCS) level, medical comorbidities, feeding tube status, seizure history, intervention type, and prevalence of PFO-related surgical complications and associated treatments were evaluated. Multivariate regression analysis was performed to determine risk factors for all surgical complications. Results: During a 5.8-year (± 3.8 years) follow-up, at least 1 surgical complication was identified in 143 (13.1%) hips in 121 (21.5%) patients after PFO in children with CP. Of these complications, the most common was heterotopic ossification (65 [6%] of hips); most of which were asymptomatic and required no treatment. Other complications included 25 (2%) nonunions, 21 (2%) deep or superficial infections, 13 (1%) delayed unions, 12 (1%) peri-implant fractures, and 7 early implant failures (0.64). The rate of revision surgery due to these complications was 13.1% (6.8% of hips), of which 41% (30 revision surgeries) were for the treatment of nonunion. Regarding the development of delayed union or nonunion, dystonia, GMFCS level IV/V, and seizure history were identified as risk factors by multivariate analysis. Conclusions: The prevalence of surgical complications after PFO was 13.1% with 6.8% of hips requiring revision surgery. Dystonia, seizure history, and nonambulatory status were the strongest predictors for the need for revision surgery after PFO. These data can be used to help counsel patients and families regarding the risks associated with PFO for children with CP. Level of proof: IV; retrospective study. [ABSTRACT FROM AUTHOR]
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- 2024
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123. Mobility and gait in adults with cerebral palsy: Evaluating change from adolescence.
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Lennon, Nancy, Church, Chris, Shrader, M. Wade, Robinson, William, Henley, John, Salazar-Torres, Jose de Jesus, Niiler, Tim, and Miller, Freeman
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CEREBRAL palsy , *OPERATIVE surgery , *GAIT disorders , *GROSS motor ability , *HEALTH outcome assessment , *RESEARCH , *NEUROLOGICAL disorders , *GAIT in humans , *RESEARCH methodology , *MEDICAL cooperation , *EVALUATION research , *COMPARATIVE studies , *DISEASE complications - Abstract
Background: Previous studies have looked at the short-term effectiveness of conservative and surgical treatment of children with cerebral palsy (CP), but few have explored the long-term outcomes into adulthood using gait analysis and patient-reported outcome measures.Research Question: How do gait, mobility, and patient-reported outcomes in adults with CP who received specialized pediatric orthopedic care change from adolescence?Methods: We identified 645 adults with 1) CP, 2) age 25-45 years, and 3) an adolescent instrumented gait analysis (IGA) at our center. Measurement outcomes included physical examination, IGA, and select domains of the Patient-Reported Outcomes Measurement Information System (PROMIS).Results: Participants included 136 adults with CP; Gross Motor Function Classification System levels I (21 %), II (51 %), III (22 %), and IV (7%); 57 % males; and average age 16 ± 3/29 ± 3 years (adolescent/adult visits). There was no significant difference in gait deviation index, stride length, or gross motor function between adolescent and adult visits. There were statistically significant but not clinically meaningful declines in gait velocity. At adulthood, PROMIS results revealed limitations in physical function compared with a normative sample but no differences in depression, participation, or pain interference.Significance: In this relatively homogeneous group of adults with CP who received orthopedic care from one center, gait and gross motor function showed no clinically meaningful change from adolescence, which differs from recent reports of declining mobility in adulthood. Expert orthopedic care, guided by IGA, may prevent losses in functional mobility for adults with CP. [ABSTRACT FROM AUTHOR]- Published
- 2021
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124. 3.5 mm Lag Screws as Compared With 6.5 mm Lag Screws for Fixation of the Distal Femur: Implications for Reconstruction of Complex Joint Injuries.
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Gupta, Anjali, McCamley, John, Shrader, M. Wade, Csavina, Kristine, Jacofsky, David J., and Tornetta III, Paul
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- 2007
125. Distal femoral extension osteotomy and patellar tendon advancement or shortening in ambulatory children with cerebral palsy: A modified Delphi consensus study and literature review.
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Rutz, Erich, Novacheck, Tom F, Dreher, Thomas, Davids, Jon R, McCarthy, James, Kay, Robert M, Shore, Benjamin J, Shrader, M Wade, Veerkamp, Matthew, Chambers, Hank, Narayanan, Unni, Pierz, Kristan, Rhodes, Jason, Shilt, Jeffrey, Theologis, Tim, Van Campenhout, Anja, and Graham, Kerr
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PATELLAR tendon , *CHILDREN with cerebral palsy , *DELPHI method , *JUMPER'S knee , *OSTEOTOMY - Abstract
Purpose: In children with cerebral palsy, flexion deformities of the knee can be treated with a distal femoral extension osteotomy combined with either patellar tendon advancement or patellar tendon shortening. The purpose of this study was to establish a consensus through expert orthopedic opinion, using a modified Delphi process to describe the surgical indications for distal femoral extension osteotomy and patellar tendon advancement/patellar tendon shortening. A literature review was also conducted to summarize the recent literature on distal femoral extension osteotomy and patellar tendon shortening/patellar tendon advancement. Method: A group of 16 pediatric orthopedic surgeons, with more than 10 years of experience in the surgical management of children with cerebral palsy, was established. The group used a 5-level Likert-type scale to record agreement or disagreement with statements regarding distal femoral extension osteotomy and patellar tendon advancement/patellar tendon shortening. Consensus for the surgical indications for distal femoral extension osteotomy and patellar tendon advancement/patellar tendon shortening was achieved through a modified Delphi process. The literature review, summarized studies of clinical outcomes of distal femoral extension osteotomy/patellar tendon shortening/patellar tendon advancement, published between 2008 and 2022. Results: There was a high level of agreement with consensus for 31 out of 44 (70%) statements on distal femoral extension osteotomy. Agreement was lower for patellar tendon advancement/patellar tendon shortening with consensus reached for 8 of 21 (38%) of statements. The literature review included 25 studies which revealed variation in operative technique for distal femoral extension osteotomy, patellar tendon advancement, and patellar tendon shortening. Distal femoral extension osteotomy and patellar tendon advancement/patellar tendon shortening were generally effective in correcting knee flexion deformities and extensor lag, but there was marked variation in outcomes and complication rates. Conclusion: The results from this study will provide guidelines for surgeons who care for children with cerebral palsy and point to unresolved questions for further research. Level of evidence: level V. [ABSTRACT FROM AUTHOR]
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- 2022
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126. Finding consensus for hamstring surgery in ambulatory children with cerebral palsy using the Delphi method.
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Kay, Robert M., McCarthy, James, Narayanan, Unni, Rhodes, Jason, Rutz, Erich, Shilt, Jeffrey, Shore, Benjamin J., Veerkamp, Matthew, Shrader, M. Wade, Theologis, Tim, Van Campenhout, Anja, Pierz, Kristan, Chambers, Henry, Davids, Jon R., Dreher, Thomas, Novacheck, Tom F., and Graham, Kerr
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CHILDREN with cerebral palsy , *DELPHI method , *PEDIATRIC surgery , *ORTHOPEDIC surgery , *SURGICAL indications , *OPERATIVE surgery , *ORTHOPEDISTS - Abstract
Purpose: There is marked variation in indications and techniques for hamstring surgery in children with cerebral palsy. There is particular uncertainty regarding the indications for hamstring transfer compared to traditional hamstring lengthening. The purpose of this study was for an international panel of experts to use the Delphi method to establish consensus indications for hamstring surgery in ambulatory children with cerebral palsy. Methods: The panel used a five-level Likert-type scale to record agreement or disagreement with statements regarding hamstring surgery, including surgical indications and techniques, post-operative care, and outcome measures. Consensus was defined as at least 80% of responses being in the highest or lowest two of the five Likert-type ratings. General agreement was defined as 60%–79% falling into the highest or lowest two ratings. There was no agreement if neither of these thresholds was reached. Results: The panel reached consensus or general agreement for 38 (84%) of 45 statements regarding hamstring surgery. The panel noted the importance of assessing pelvic tilt during gait when considering hamstring surgery, and also that lateral hamstring lengthening is rarely needed, particularly at the index surgery. They noted that repeat hamstring lengthening often has poor outcomes. The panel was divided regarding hamstring transfer surgery, with only half performing such surgery. Conclusion: The results of this study can help pediatric orthopedic surgeons optimize decision-making in their choice and practice of hamstring surgery for ambulatory children with cerebral palsy. This has the potential to reduce practice variation and significantly improve outcomes for ambulatory children with cerebral palsy. [ABSTRACT FROM AUTHOR]
- Published
- 2022
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127. Distal rectus femoris surgery in children with cerebral palsy: results of a Delphi consensus project.
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Kay, Robert M., Pierz, Kristan, McCarthy, James, Graham, H. Kerr, Chambers, Henry, Davids, Jon R., Narayanan, Unni, Novacheck, Tom F., Rhodes, Jason, Rutz, Erich, Shilt, Jeffrey, Shore, Benjamin J., Veerkamp, Matthew, Shrader, M. Wade, Theologis, Tim, Van Campenhout, Anja, and Dreher, Thomas
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RECTUS femoris muscles , *CHILDREN with cerebral palsy , *PEDIATRIC surgery , *DELPHI method , *LIKERT scale - Abstract
Purpose: The purpose of this study was for an international panel of experts to establish consensus indications for distal rectus femoris surgery in children with cerebral palsy (CP) using a modified Delphi method. Methods: The panel used a five-level Likert scale to record agreement or disagreement with 33 statements regarding distal rectus femoris surgery. The panel responded to statements regarding general characteristics, clinical indications, computerized gait data, intraoperative techniques and outcome measures. Consensus was defined as at least 80% of responses being in the highest or lowest two of the five Likert ratings, and general agreement as 60% to 79% falling into the highest or lowest two ratings. There was no agreement if neither threshold was reached. Results: Consensus or general agreement was reached for 17 of 33 statements (52%). There was general consensus that distal rectus femoris surgery is better for stiff knee gait than is proximal rectus femoris release. There was no consensus about whether the results of distal rectus femoris release were comparable to those following distal rectus femoris transfer. Gross Motor Function Classification System (GMFCS) level was an important factor for the panel, with the best outcomes expected in children functioning at GMFCS levels I and II. The panel also reached consensus that they do distal rectus femoris surgery less frequently than earlier in their careers, in large part reflecting the narrowing of indications for this surgery over the last decade. Conclusion: This study can help paediatric orthopaedic surgeons optimize decision-making for, and outcomes of, distal rectus femoris surgery in children with CP. [ABSTRACT FROM AUTHOR]
- Published
- 2021
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128. Indications for gastrocsoleus lengthening in ambulatory children with cerebral palsy: a Delphi consensus study.
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Rutz, Erich, McCarthy, James, Shore, Benjamin J., Shrader, M. Wade, Veerkamp, Matthew, Chambers, Henry, Davids, Jon R., Kay, Robert M., Narayanan, Unni, Novacheck, Tom F., Pierz, Kristan, Rhodes, Jason, Shilt, Jeffrey, Theologis, Tim, Van Campenhout, Anja, Dreher, Thomas, and Graham, Kerr
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CHILDREN with cerebral palsy , *PEDIATRIC orthopedics , *DELPHI method , *SURGICAL indications , *ACHILLES tendon , *ACHILLES tendon rupture , *DROOLING - Abstract
Purpose Equinus is the most common deformity in cerebral palsy (CP) and gastrocsoleus lengthening (GSL) is the most commonly performed surgery to improve gait and function in ambulatory children with CP. Substantial variation exists in the indications for GSL and surgical technique. The purpose of this study was to review surgical anatomy and biomechanics of the gastrocsoleus and to utilize expert orthopaedic opinion through a Delphi technique to establish consensus for surgical indications for GSL in ambulatory children with CP. Methods A 17-member panel, of Fellowship-trained paediatric orthopaedic surgeons, each with at least 9 years of clinical post-training experience in the surgical management of children with CP, was established. Consensus for the surgical indications for GSL was achieved through a standardized, iterative Delphi process. Results Consensus was reached to support conservative Zone 1 surgery in diplegia and Zone 3 surgery (lengthening of the Achilles tendon) was contraindicated. Zone 2 or Zone 3 surgery reached general agreement as a choice in hemiplegia and under-correction was preferred to any degree of overcorrection. Agreement was reached that the optimum age for GSL surgery was 6 years to 10 years and should be avoided in children aged under 4 years. Physical examination measures with the child awake and under anaesthesia were important in decision making. Gait analysis was supported both for decision making and for assessing outcomes, in combination with patient reported outcomes (PROMS). Conclusions The results from this study may encourage informed practice evaluation, reduce practice variability, improve clinical outcomes and point to questions for further research. [ABSTRACT FROM AUTHOR]
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- 2020
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129. Scoliosis Development in Spinal Muscular Atrophy: The Influences of Genetic Severity, Functional Level, and Disease-Modifying Treatments.
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Ciftci S, Ulusaloglu AC, Shrader MW, Scavina MT, Mackenzie WG, Heinle R, Neal KM, Stall A, and Howard JJ
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- Humans, Female, Male, Retrospective Studies, Child, Risk Factors, Child, Preschool, Muscular Atrophy, Spinal genetics, Follow-Up Studies, Oligonucleotides therapeutic use, Adolescent, Prevalence, Scoliosis genetics, Severity of Illness Index
- Abstract
Background: Spinal muscular atrophy (SMA) is caused by abnormalities of the survival motor neuron (SMN) 1 gene, leading to deficiency in SMN protein and loss of spinal cord alpha motor neurons. Newer disease-modifying agents (DMA) targeting the involved genes, including nusinersen and gene replacement therapies, have improved gross motor and respiratory function, but their impact on scoliosis development has not been established. This study aimed to determine risk factors for scoliosis development in SMA, specifically genetic severity and DMA use., Methods: In this retrospective cohort study, children with SMA and minimum 2-year follow-up were included. The primary outcome was the prevalence of clinically relevant scoliosis. Secondary outcomes included SMA type, SMN2 copy number, Hammersmith Functional Motor Scale (HFMS), ambulatory status [functional mobility scale at 50m (FMS 50 )], DMA use, and hip displacement as risk factors. Univariate/multivariate logistic regression analyses were performed to identify dependent/independent risk factors., Results: One hundred sixty-five patients (51% female) with SMA types I-III met the inclusion criteria, with total follow-up of 9.8 years. The prevalence of scoliosis was 79%; age of onset 7.9 years. The major curve angle for the entire cohort at first assessment and final follow-up was 37 degrees (SD: 27 degrees) and 62 degrees (SD: 31 degrees) ( P <0.0001), respectively. Significant risk factors for scoliosis by univariate analysis were SMA type (I/II, P =0.02), HFMS (>23, P <0.001), nonambulatory status (FMS 50 =1, P <0.0001), DMA treatment ( P =0.02), and hip displacement ( P <0.0001). Multivariate analysis revealed that HFMS >23 ( P =0.02) and DMA ( P =0.05) treatment were independent (protective) risk factors., Conclusions: The development of scoliosis in SMA is high, with risk factors associated with proxy measures of disease severity, including SMA type, nonambulatory status, hip displacement, and most notably, gross motor function (by HFMS). DMA use and HFMS >23 were associated with a decreased risk of scoliosis development. Identified risk factors can be used in the development of surveillance programs for early detection of scoliosis in SMA., Level of Evidence: Level III., Competing Interests: The authors declare no conflicts of interest., (Copyright © 2024 Wolters Kluwer Health, Inc. All rights reserved.)
- Published
- 2024
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130. Reliability of a Photo-Based Modified Foot Posture Index (MFPI) in Quantifying Severity of Foot Deformity in Children With Cerebral Palsy.
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Georgiadis AG, Davids JR, Goodbody CM, Howard JJ, Karamitopoulos MS, Payares-Lizano M, Pierz KA, Rhodes JT, Shore BJ, Shrader MW, Tabaie SA, Thompson RM, Torres-Izquierdo B, Wimberly RL, and Hosseinzadeh P
- Abstract
Introduction: Children with cerebral palsy (CP) have high rates of foot deformity. Accurate assessment of foot morphology is crucial for therapeutic planning and outcome evaluation. This study aims to evaluate the reliability of a novel photo-based Modified Foot Posture Index (MFPI) in the evaluation of foot deformity in children with CP., Methods: Thirteen orthopaedic surgeons with neuromuscular clinical focus from 12 institutions evaluated standardized standing foot photographs of 20 children with CP, scoring foot morphology using the MFPI. Raters scored the standardized photographs based on five standard parameters. Two parameters assessed the hindfoot: curvature above and below the malleoli and calcaneal inversion/eversion. Three parameters assessed the midfoot and forefoot: talonavicular congruence, medial arch height, and forefoot abduction/adduction. Summary MFPI scores range from -10 to +10, where positive numbers connote planovalgus, whereas negative numbers connote a tendency toward cavovarus. Intra- and interrater reliability were calculated using a 2-way mixed model of the intraclass correlation coefficient (ICC) set to absolute agreement., Results: Feet spanned the spectrum of potential pathology assessable by the MFPI, including no deformity, mild, moderate, and severe planovalgus or cavovarus deformities. All scored variables showed high intrarater reliability with ICCs from 0.891 to 1. ICCs for interrater reliability ranged from 0.965 to 0.984. Hindfoot total score had an ICC of 0.979, with a 95% CI, 0.968-0.988 (P<0.001). The forefoot total score had an ICC of 0.984 (95% CI, 0.976-0.991, P<0.001). Mean total score by the MFPI was 3.67 with an ICC of 0.982 (95% CI, 0.972-0.990, P<0.001)., Conclusions: The photo-based MFPI demonstrates high intra- and interrater reliability in assessing foot deformities in children with CP. Its noninvasive nature and ease of use make it a promising tool for both clinical and research settings. MFPI should be considered as part of standard outcomes scores in studies regarding the treatment of CP-associated foot deformities., Level of Evidence: Level V., Competing Interests: The authors declare no conflicts of interest., (Copyright © 2024 Wolters Kluwer Health, Inc. All rights reserved.)
- Published
- 2024
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131. Hip Displacement After Triradiate Closure in Ambulatory Cerebral Palsy: Who Needs Continued Surveillance?
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Lindgren AM, Asma A, Rogers KJ, Miller F, Shrader MW, and Howard JJ
- Abstract
Background: Hip surveillance in cerebral palsy (CP) is an accepted practice with evidence-based guidelines implemented. For the skeletally immature with open triradiate cartilage (TRC), recommendations for radiographic surveillance stemmed from population-based studies. For nonambulatory CP, progression of hip displacement after skeletal maturity has been reported; less is known for ambulatory CP. We aimed to determine the prevalence and risk factors associated with progressive hip displacement after TRC closure, a proxy for skeletal maturity, for ambulatory CP., Methods: This is a retrospective cohort study of patients with ambulatory CP (Gross Motor Function Classification System I-III), with unilateral or bilateral involvement, hypertonic motor type, regular hip surveillance (≥3 radiographs after age 10 yr, 1 before TRC closure, ≥1 after age 16 yr), and 2-year follow-up post-TRC closure. The primary outcome was migration percentage (MP). Other variables included previous preventative/reconstructive surgery, topographic pattern, sex, scoliosis, epilepsy, and ventriculoperitoneal shunt. An "unsuccessful hip" was defined by MP ≥30%, MP progression ≥10%, and/or requiring reconstructive surgery after TRC closure. Statistical analyses included chi-square and multivariate Cox regression. Kaplan-Meier survivorship curves were also determined. Receiver operating characteristic analysis was used to determine the MP threshold for progression to an "unsuccessful hip" after TRC closure., Results: Seventy-six patients (39.5% female) met the inclusion criteria, mean follow-up 4.7±2.1 years after TRC closure. Sixteen (21.1%) patients had an unsuccessful hip outcome. By chi-square analysis, diplegia (P=0.002) and epilepsy (P=0.04) were risk factors for an unsuccessful hip. By multivariate analysis, only first MP after TRC closure (P<0.001) was a significant risk factor for progression to an unsuccessful hip; MP ≥28% being the determined threshold (receiver operating characteristic curve analysis, area under curve: 0.845, P<0.02)., Conclusions: The risk of MP progression after skeletal maturity is relatively high (21%), similar to nonambulatory CP. Annual hip surveillance radiographs after TRC closure should continue for Gross Motor Function Classification System I-III with an MP ≥28% after TRC closure, especially for bilateral CP and epilepsy., Level of Evidence: III., Competing Interests: The authors declare no conflicts of interest., (Copyright © 2024 Wolters Kluwer Health, Inc. All rights reserved.)
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- 2024
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132. Bone alterations of pamidronate therapy in children with cerebral palsy complicating orthopedic management.
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Almeida Da Silva LC, Kaymaz B, Hori Y, Montufar Wright PE, Rogers KJ, Trionfo A, Howard JJ, Bowen JR, Shrader MW, and Miller F
- Subjects
- Humans, Child, Female, Male, Child, Preschool, Bone Density drug effects, Retrospective Studies, Adolescent, Pamidronate therapeutic use, Cerebral Palsy complications, Bone Density Conservation Agents therapeutic use
- Abstract
Cerebral palsy (CP) is a heterogeneous group of disorders with different clinical types and underlying genetic variants. Children with CP are at risk for fragility fractures secondary to low bone mineral density, and although bisphosphonates are prescribed for the treatment of children with bone fragility, there is limited information on long-term bone impact and safety. Children with CP usually present overtubulated bones, and the thickening of cortical bone by pamidronate treatment can potentially further narrow the medullary canal. Our purpose was to report bone alterations attributable to pamidronate therapy that impact orthopedic care in children with CP. The study consisted of 41 children with CP treated with pamidronate for low bone mineral density from 2006 to 2020. Six children presented unique bone deformities and unusual radiologic features attributed to pamidronate treatment, which affected their orthopedic care. The cases included narrowing of the medullary canal and sclerotic bone, atypical femoral fracture, and heterotopic ossification. Treatment with bisphosphonate reduced the number of fractures from 101 in the pretreatment period to seven in the post-treatment period ( P < 0.001). In conclusion, children with CP treated with bisphosphonate have a reduction in low-energy fractures; however, some fractures still happen, and pamidronate treatment can lead to bone alterations including medullary canal narrowing with sclerotic bone and atypical femoral fractures. In very young children, failure to remodel may lead to thin, large femoral shafts with cystic medullary canals. More widespread use of bisphosphonates in children with CP may make these bone alterations more frequent. Level of evidence: Level IV: Case series with post-test outcomes., (Copyright © 2023 Wolters Kluwer Health, Inc. All rights reserved.)
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- 2024
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133. Development and validation of a stakeholder-driven, self-contained electronic informed consent platform for trio-based genomic research studies.
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Norton BY, Liu J, Lewis SA, Magee H, Kruer TN, Dinh R, Bakhtiari S, Nordlie SH, Shetty S, Heim J, Nishiyama Y, Arango J, Johnson D, Seabrooke L, Shub M, Rosenberg R, Shusterman M, Wisniewski S, Cooper B, Rothwell E, Fahey MC, Shrader MW, Lennon N, Oleszek J, Pierce W, Fleming H, Belthur M, Tinto J, Noritz G, Glader L, Steffan K, Walker W, Grenard D, Aravamuthan B, Bjornson K, Joseph M, Gross P, and Kruer MC
- Abstract
Increasingly long and complex informed consents have yielded studies demonstrating comparatively low participant comprehension and satisfaction with traditional face-to-face approaches. In parallel, interest in electronic consents for clinical and research genomics has steadily increased, yet limited data are available for trio-based genomic discovery studies. We describe the design, development, implementation, and validation of an electronic iConsent application for trio-based genomic research deployed to support genomic studies of cerebral palsy. iConsent development incorporated stakeholder perspectives including researchers, patient advocates, institutional review board members, and genomic data-sharing considerations. The iConsent platform integrated principles derived from prior electronic consenting research and elements of multimedia learning theory. Participant comprehension was assessed in an interactive teachback format. The iConsent application achieved nine of ten proposed desiderata for effective patient-focused electronic consenting for genomic research. Overall, participants demonstrated high comprehension and retention of key human subjects' considerations. Enrollees reported high levels of satisfaction with the iConsent, and we found that participant comprehension , iConsent clarity , privacy protections , and study goal explanations were associated with overall satisfaction . Although opportunities exist to optimize iConsent, we show that such an approach is feasible, can satisfy multiple stakeholder requirements, and can realize high participant satisfaction and comprehension while increasing study reach., Competing Interests: Conflicts of Interest Paul Gross is President and CEO of the CP Research Network, which contributed to the funding of this project. Mr. Gross personally made financial contributions (donations) to CPRN to support this work, but receives no financial compensation related to either. Dr. Noritz has consulted for Abbott Nutrition, unrelated to this project. Dr. Shrader receives research funding from NIH and serves on the National Advisory Board for Medical Rehabilitative Research for NIH/NICHD.
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- 2024
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134. The impact of hamstring lengthening on stance knee flexion at skeletal maturity in ambulatory cerebral palsy.
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Kanashvili B, Niiler TA, Church C, Lennon N, Shrader MW, Howard JJ, and Miller F
- Abstract
This study reports the long-term outcomes of hamstring lengthening to treat flexed knee gait in children with ambulatory cerebral palsy (CP) after skeletal maturity. This retrospective longitudinal observational study used instrumented gait analysis (GA) <8 and >15 years old in children with bilateral CP. The primary variable was knee flexion in stance phase. Eighty children (160 limbs) were included; 49% were male, 51% female. Mean age at first GA was 6.0 (SD: 1.2) years and 19.6 (SD: 4.5) years at final GA. Mean follow-up was 13.7 (SD: 4.7) years. Children were classified as Gross Motor Function Classification System I-8, II-46 and III-26. Average Gross Motor Function Measure Dimension D was 72% (SD: 20%). Hamstring lengthenings occurred once in 82, twice in 54 and three times in 10 limbs. From initial to final GA, average knee flexion in stance was unchanged, 27.8° (SD: 14.8°) to final 27.0° (SD: 11.2°; P = 0.54). Knee flexion at foot contact was 39.6° (SD: 13.0°), improving to final GA of 30.7° (SD: 10.6°; P < 0.001). Initial gait deviation index was 65.8 (SD: 31.9), improving to final 78.9 (SD: 28.2; P < 0.001). Older age, males and concomitant plantar flexor lengthening predicted change toward more flexed knee gait. Hamstring lengthening did not lead to back-kneeing gait at maturity while maintaining childhood stance phase knee flexion. A subgroup still developed significant flexed knee gait posture and may have benefited from more aggressive treatment options. This outcome may also be impacted by diverse functional levels, etiologies and treatments of flexed knee gait., (Copyright © 2024 Wolters Kluwer Health, Inc. All rights reserved.)
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- 2024
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135. Surgery for foot deformities in MECP2 disorders: prevalence and risk factors.
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Kanashvili B, Shrader MW, Rogers KJ, Miller F, and Howard JJ
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- Adolescent, Child, Female, Humans, Male, Prevalence, Retrospective Studies, Risk Factors, Tenotomy, Young Adult, Clubfoot surgery, Hip Dislocation complications, Scoliosis epidemiology, Scoliosis genetics, Scoliosis surgery
- Abstract
Foot deformities in methyl-CpG binding protein 2 (MECP2) disorders are thought to be common, but reports are scant. The purpose of this study was to report the prevalence and type of foot deformities and surgical management for MECP2 disorders. In this retrospective, comparative study, all children presenting between June 2005 and July 2020, with a genetically confirmed MECP2-related disorder, were included. The primary outcome measure was the prevalence of surgery for foot deformities. Secondary outcomes included type and frequency of foot surgeries, age at surgery, ambulatory status, genetic severity, presence of scoliosis/hip displacement, seizures, and associated comorbidities. Chi-square testing was utilized for the analysis of risk factors. Fifty-six patients (Rett syndrome: N = 52, MECP2 duplication syndrome: N = 4; 93% female) met the inclusion criteria. The mean age at first presentation to orthopedics was 7.3 (SD, 3.9) years, with a final follow-up of 4.5 (SD, 4.9) years. Seven (13%) patients developed foot deformities, most commonly equinus or equinovarus (five patients, 71%), requiring surgical management. The remaining two patients had calcaneovalgus. The most common surgical procedure was Achilles tendon lengthening, followed by triple arthrodesis, at a mean age of 15.9 (range: 11.4-20.1) years. Hip displacement ( P = 0.04), need for hip surgery ( P = 0.001) and clinically relevant scoliosis ( P = 0.04) were significant risk factors for the development of symptomatic foot deformities. Although not as prevalent as scoliosis or hip displacement, foot deformities are still relatively common in MECP2 disorders, often necessitating surgical intervention to improve brace tolerance. Level of evidence: Level III - a retrospective comparative study., (Copyright © 2023 Wolters Kluwer Health, Inc. All rights reserved.)
- Published
- 2024
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136. Transcranial electric motor evoked potential monitoring during scoliosis surgery in children with cerebral palsy and active seizure disorder: is it feasible and safe?
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Shrader MW, DiCindio S, Kenny KG, Franco AJ, Zhang R, Theroux MC, Rogers KJ, and Shah SA
- Abstract
Purpose: Use of spinal cord monitoring in children with cerebral palsy (CP) and neuromuscular scoliosis is challenging. The previous reports suggest low success rates in the setting of CP, and it is unclear if transcranial electric motor evoked potentials (TcMEP) monitoring is contraindicated in patients with an active seizure disorder. The purpose of this study was to determine (1) are patients with CP able to be appropriately monitored with TcMEP? and (2) does TcMEP cause an increase in seizure activity?, Methods: This was an institutional review board-approved retrospective cohort study observing 304 patients from 2011 to 2020. Inclusion criteria included all patients with CP undergoing posterior spinal fusion during this time. Intraoperative data were examined for the ability to obtain monitoring and any intraoperative events. Patients were followed for 3 months postoperatively to determine any increase in seizure activity that could have been attributed to the TcMEP monitoring., Results: Of the 304 patients who were observed, 21% (20.8%) were unable to be monitored due to lacking baseline signals from the extremities. Seventy-seven percent (77.5%) were successfully monitored with TcMEP. For these patients, no increased seizure activity was documented either intra- or postoperatively., Conclusion: A high percentage of children (77.5%) with CP were able to be successfully monitored with TcMEP during posterior spinal fusion. Furthermore, the concerns about increased seizure activity after TcMEP were not supported by the data from this cohort. Technical details of successful neuromonitoring in these patients are important and included increased stimulation voltage requirements and latency times., Level of Evidence: III retrospective comparative study., (© 2023. The Author(s), under exclusive licence to Scoliosis Research Society.)
- Published
- 2023
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137. Identification of risk factors for reconstructive hip surgery after intrathecal baclofen therapy in children with cerebral palsy.
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Asma A, Howard JJ, Ulusaloglu AC, Rogers KJ, Miller F, and Shrader MW
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- Humans, Child, Male, Child, Preschool, Baclofen, Muscle Spasticity etiology, Muscle Spasticity complications, Radiography, Risk Factors, Cerebral Palsy complications
- Abstract
Objective: This study aimed to determine the risk factors for reconstructive hip surgery after intrathecal baclofen pump application in children with cerebral palsy., Methods: Inclusion criteria were children with hypertonic (spastic or mixed spastic/dystonic motor type) cerebral palsy, intrathecal baclofen implantation <8 years of age, no reconstructive osteotomies prior to or concomitant with intrathecal baclofen implantation and at least a 5-year follow-up. Exclusion criteria included reconstructive osteotomies prior to or concurrent with intrathecal baclofen implantation, lack of at least 1 hip surveillance radiograph before intrathecal baclofen, lack of a 5-year follow-up, or having selective dorsal rhizotomy. In addition, patients with bony surgery plus last follow-up migration percentage ≥50% were labeled as required reconstruction hips., Results: We identified 34 patients (68 hips). The mean follow-up was 9.2 ± 2.8 years. The mean age for intrathecal baclofen application was 6.4 ± 1.2 years. Seven patients were Gross Motor Function Classification System IV, and 27 were V. Eighteen patients (52.9%) with 31 hips (45.6%) were requiring reconstruction at the final follow-up. In multivariate analysis, male sex (odds ratio 12.8, P=.012), pre-intrathecal baclofen migration percentage (odds ratio 1.1, P=0.003), age at intrathecal baclofen implantation (odds ratio 0.24, P=.002), and delta migration percentage (odds ratio 1.1, P=.002) were significant risk factors for requiring reconstruction. Patients with intrathecal baclofen <6.2 years of age had a significantly higher rate of requiring reconstruction. A pre-intrathecal baclofen migration percentage >31% had a greater risk of progression to requiring reconstruction (P=.001). Delta migration percentage higher than 15% was significantly associated with progression to requiring reconstruction (P=.043)., Conclusion: The risk of requiring reconstruction osteotomies after intrathecal baclofen was significantly increased in males, those younger (±migration percentage >31%) at the time of intrathecal baclofen implantation and those with an increased rate of migration percentage progression after intrathecal baclofen implantation., Level of Evidence: Level IV, Prognostic Study.
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- 2023
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138. The effect of medial only versus medial and lateral hamstring lengthening on transverse gait parameters in cerebral palsy.
- Author
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Bezuidenhout L, Church C, Henley J, Salazar-Torres JJ, Lennon N, Shields T, Miller F, and Shrader MW
- Subjects
- Adolescent, Child, Child, Preschool, Humans, Gait, Cerebral Palsy complications, Cerebral Palsy surgery
- Abstract
Benefits of hamstring lengthening surgery on the sagittal plane in children with cerebral palsy have been previously demonstrated, but there is limited information on its effects on the transverse plane. This study compared the effects of medial hamstring lengthening (MHL) with those of medial and lateral hamstring lengthening (MLHL) procedures in the transverse plane. Children with gross motor function classification system (GMFCS) levels I-III who had MHL or MLHL were included. Baseline, short- (1-2 years), and long-term (3+ years) postoperative three-dimensional gait analysis outcomes were compared using analysis of variance. Children were excluded if they had concurrent osteotomies or tendon transfers. One hundred fifty children (235 limbs) were included, with 110 limbs in the MHL group (age 8.5 ± 4.1 years, GMFCS I-27%, II-52%, and III-21%) and 125 limbs in the MLHL group (age 10.0 ± 4.0 years, GMFCS I-23%, II-41%, and III-37%). Time between surgery and short- and long-term follow-up gait analysis was 1.5 ± 0.6 years and 6.6 ± 2.9 years, respectively. Transmalleolar axis became more external after MHL at both short and long terms ( P < 0.05), whereas there were only significant differences at long term in MLHL ( P < 0.05). Although hamstring lengthening has a positive impact on stance phase knee extension in children with cerebral palsy, intact lateral hamstrings after MHL likely contribute to increased tibial external rotation after surgery. Significant increases in external rotation at the knee in the long term are likely related to a trend present with growth in children with cerebral palsy rather than a direct result of surgical intervention., (Copyright © 2022 Wolters Kluwer Health, Inc. All rights reserved.)
- Published
- 2023
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139. Missed fractures in paediatric trauma patients.
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Segal LS and Shrader MW
- Subjects
- Child, Fractures, Closed diagnosis, Humans, Multiple Trauma, Pelvic Bones injuries, Quality of Health Care, Spinal Fractures diagnosis, Diagnostic Errors, Fractures, Bone diagnosis
- Abstract
Missed fractures and other occult musculoskeletal injuries are common in paediatric trauma patients despite the thorough evaluation with standard trauma protocols. Several factors have been identified that contribute to the risk of failing to identify these injuries during the initial resuscitation and assessment of the paediatric trauma patient. These include patient-related, clinical, technical, and radiological causes. Preventive strategies have been proposed to minimize these overlooked injuries and their potential long-term consequences. A timely review of this problem is appropriate to continually improve the quality of care delivered to paediatric trauma patients.
- Published
- 2013
140. Pulmonary embolism following an ankle fracture in a 9-year-old boy: a case report.
- Author
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Shrader MW, Ho AK, Notrica DM, and Segal LS
- Subjects
- Ankle Injuries diagnostic imaging, Ankle Injuries surgery, Child, Fractures, Bone diagnostic imaging, Fractures, Bone surgery, Humans, Male, Pulmonary Embolism diagnostic imaging, Pulmonary Embolism surgery, Radiography, Treatment Outcome, Ankle Injuries complications, Fracture Fixation, Internal adverse effects, Fractures, Bone complications, Pulmonary Embolism etiology
- Abstract
Venous thromboembolism following trauma is an uncommon event in childhood and associated pulmonary embolus after routine lower extremity fracture is exceedingly rare. We present a case report of postoperative pulmonary embolus following an open reduction and internal fixation of a Salter-Harris IV medial malleolus fracture in a 9-year-old boy. Four days after open reduction and percutaneous pin fixation of the ankle fracture, the child began to experience chest pain and shortness of breath. Computed tomographic angiography demonstrated a pulmonary embolus, and he was started on anticoagulation therapy. The child had no medical history, family history, nor known risk factors for venous thromboembolism other than the fracture, and a thrombophilic work-up revealed no coagulopathies or other blood disorders. He was treated with Coumadin for three months. His orthopedic course was uneventful; the fracture healed and he returned to normal function. This appears to be the first case reported in the literature of a significant pulmonary embolus after a routine ankle fracture in a child. While insufficient to warrant deep venous thrombosis prophylaxis in all children, this case report suggests that a venous thromboembolic event can occur even in uncomplicated fractures in children.
- Published
- 2012
141. Periosteal entrapment in distal femoral physeal fractures: harbinger for premature physeal arrest ?
- Author
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Segal LS and Shrader MW
- Subjects
- Child, Epiphyses growth & development, Epiphyses pathology, Femoral Fractures complications, Femoral Fractures diagnosis, Femur diagnostic imaging, Femur growth & development, Humans, Magnetic Resonance Imaging, Male, Periosteum pathology, Radiography, Epiphyses injuries, Femoral Fractures pathology, Football injuries, Periosteum injuries
- Abstract
We report on two patients who sustained Salter-Harris II fractures of the distal femur with physeal widening after being tackled in football games. Preoperative MRI indicated entrapped periosteum at the physeal fracture site for both patients. Both patients underwent open reduction of the physeal fracture with removal of the entrapped periosteum and achieving an anatomic reduction. Follow-up MRI's revealed premature physeal arrest. Subsequent procedures were performed to address sequelae of premature physeal arrest. The presence of physeal widening and entrapped periosteum may reflect high-energy trauma to the physis. This can result in injury to both the epiphyseal blood supply and to the physeal cartilage (germinal zone) resulting in physeal arrest despite anatomic reduction after removal of the entrapped periosteum. Upon literature review, pre-operative MRI demonstrating entrapped periosteum has not been previously reported. We hypothesize that the presence of entrapped periosteum following distal femoral physeal fractures may be associated with an increased risk for premature physeal arrest.
- Published
- 2011
142. Nonunion of fractures in pediatric patients: 15-year experience at a level I trauma center.
- Author
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Shrader MW, Stans AA, Shaughnessy WJ, and Haidukewych GJ
- Subjects
- Child, Child, Preschool, Female, Fractures, Malunited diagnostic imaging, Humans, Incidence, Male, Pediatrics statistics & numerical data, Radiography, Retrospective Studies, Risk Assessment, Risk Factors, Trauma Centers statistics & numerical data, Treatment Failure, United States epidemiology, Fractures, Malunited epidemiology, Fractures, Malunited surgery
- Abstract
There is little data evaluating the risk factors, demographics, and prognoses for nonunions in children. Previous literature has reviewed time periods when contemporary techniques of internal fixation and management of open injuries had not been available. The purpose of this retrospective study was to evaluate a large consecutive series of pediatric nonunions treated at a level I trauma center. Between 1985 and 2000, 43 nonunions in 42 pediatric patients with a mean age of 9 years and 9 months (range, 3-14 years) were identified at our level I trauma center. Eleven of the original 43 fractures were open and 5 presented with active infection. Patients were observed until union or a minimum of 1 year with a mean follow-up of 50 months. Twenty of 43 nonunions (47%) were located around the elbow. Seventeen of 43 nonunions (39%) were diaphyseal. The operative fractures required a mean of 3.6 surgeries (range, 1-19 surgeries) to achieve bony union. All secondary attempts to achieve union were successful at last follow-up. Although nonunions in the pediatric population are rare, these data underscore the importance of careful evaluation and treatment of these fractures at risk for nonunion.
- Published
- 2009
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143. Pathologic femoral neck fractures in children.
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Shrader MW, Schwab JH, Shaughnessy WJ, and Jacofsky DJ
- Subjects
- Adolescent, Child, Child, Preschool, Female, Femoral Neck Fractures etiology, Femoral Neck Fractures surgery, Femur Neck injuries, Fracture Healing, Humans, Infant, Male, Postoperative Complications, Femoral Neck Fractures pathology, Femur Neck pathology, Orthopedic Procedures
- Abstract
Pathologic fractures in children occur in a variety of malignant and benign pathologic processes. Pediatric pathologic femoral neck fractures are particularly rare. Until now, all reported cases have been isolated cases, small series, or cases reported in series of adult pathologic hip fractures. The present article is the first report of a relatively large series of pathologic femoral neck fractures in a pediatric population. We identified pathologic femoral neck fractures, including 2 basicervical fractures, in 15 children (9 boys, 6 girls) ranging in age from 18 months to 15 years (mean age, 9 years) and treated between 1960 and 2000. The pathologic diagnoses were fibrous dysplasia (5 children), unicameral bone cyst (2), Ewing's sarcoma (2), osteomyelitis (2), leukemia (1), rhabdomyosarcoma (1), osteogenesis imperfecta (1), and osteopetrosis (1). Treatment methods, including time to reduction and fixation, were reviewed in detail. One patient was lost to follow-up. All others were followed until union; mean long-term follow-up was 7 years (range, 1-16 years). All patients ultimately went on to union. Mean time to union was 19 weeks (range, 5-46 weeks). However, 2 patients died before 2 years. There was a 40% complication rate, with limb-length discrepancy being the most common (4 children). No patient developed avascular necrosis. Pathologic femoral neck fractures are rare in children. Pediatric patients who present with a pathologic hip fracture are at significant risk for complications. Physicians and family should be alerted to the prolonged course involved in treating these fractures to union.
- Published
- 2009
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