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1,557 results on '"Shinoda, M"'

109. Development of trapezoid-shaped Nd-Fe-B die-upset magnets by preform method

Author

Iwasaki, K., Shinoda, M., Tanigawa, S., and Tokunaga, M.

Subjects
Magnets -- Design and construction, Business, Electronics, Electronics and electrical industries
Abstract

Basic investigations to apply rapid quenched Nd-Fe-B die-upset technique to fabricate trapezoid-shaped magnets with high energy product were undertaken. Stress around the magnets with indentations during die-upsetting was evaluated by computer simulation. The dimensions of preform shape for isotropic consolidated magnets before hot deformation were determined from compression tests using an aluminum alloy. Further, hot deformation to get final trapezoid-shape were divided into two steps. The total reduction in height during compression exceeded similar 72% and the finished magnets had no cracks. By this method, we have fabricated trapezoid-shaped die-upset magnets with a high energy product of greater than 320kJ/m cubed.

Published
1992

111. Dryland climate change: Recent progress and challenges

Author

Huang, J., primary, Li, Y., additional, Fu, C., additional, Chen, F., additional, Fu, Q., additional, Dai, A., additional, Shinoda, M., additional, Ma, Z., additional, Guo, W., additional, Li, Z., additional, Zhang, L., additional, Liu, Y., additional, Yu, H., additional, He, Y., additional, Xie, Y., additional, Guan, X., additional, Ji, M., additional, Lin, L., additional, Wang, S., additional, Yan, H., additional, and Wang, G., additional

Published
2017
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113. Treatment with sofosbuvir and ledipasvir without ribavirin for 12 weeks is highly effective for recurrent hepatitis C after living donor liver transplantation: a Japanese multicenter experience

Author

Ueda, Y., primary, Ikegami, T., additional, Akamatsu, N., additional, Soyama, A., additional, Shinoda, M., additional, Goto, R., additional, Okajima, H., additional, Yoshizumi, T., additional, Taketomi, A., additional, Kitagawa, Y., additional, Eguchi, S., additional, Kokudo, N., additional, Uemoto, S., additional, and Maehara, Y., additional

Published
2017
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114. RHIC forward experiment to study √sdependence of forward particle production

Author

Sako, T., primary, Adriani, O., additional, Bonechi, L., additional, D'Alessandro, R., additional, Goto, Y., additional, Itow, Y., additional, Kasahara, K., additional, Kim, M., additional, Makino, Y., additional, Matsubayashi, E., additional, Menjo, H., additional, Nakagawa, I., additional, Park, J., additional, Sakurai, N., additional, Sato, K., additional, Seidl, R., additional, Shinoda, M., additional, Suzuki, T., additional, Tanida, K., additional, Torii, S., additional, Tricomi, A., additional, Ueno, M., additional, and Zhou, Q.D., additional

Published
2017
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116. Effects of physical training on body composition and organ weights in ovariectomized and hyperestrogenic rats

Author

Martin G. Latour, Jean-Marc Lavoie, and Shinoda M

Subjects
medicine.medical_specialty, medicine.drug_class, Ovariectomy, Endocrinology, Diabetes and Metabolism, Uterus, Medicine (miscellaneous), Blood lipids, Physical exercise, Fatty Acids, Nonesterified, Rats, Sprague-Dawley, Physical Conditioning, Animal, Internal medicine, Adrenal Glands, Animals, Medicine, Femur, Muscle, Skeletal, Lung, Triglycerides, Nutrition and Dietetics, Estradiol, business.industry, Cholesterol, HDL, Organ Size, medicine.disease, Obesity, Rats, Cholesterol, medicine.anatomical_structure, Endocrinology, Adipose Tissue, Estrogen, Body Composition, Ovariectomized rat, Female, Plantaris muscle, business, hormones, hormone substitutes, and hormone antagonists
Abstract

OBJECTIVE: To investigate whether regular endurance-type exercise can benefit rats submitted to a model of ovariectomy (OVX)-induced obesity with or without estrogen replacement. SUBJECTS: OVX Sprague-Dawley rats were compared to an ovariectomized-estradiol-treated group (OVXE2) and a Sham-operated (Sham) group. Each of these groups were subdivided into a sedentary and a treadmill-trained (8 wk) group. DESIGN AND MEASUREMENTS: An experimental study in which various parameters, including fat depots, blood lipids and several organ weights were measured. RESULTS: Plasma levels of 17β-estradiol and uterus weights were significantly (P

Published
2002
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125. 21st Computed Maxillofacial Imaging Congress

Author

Hayakawa, Y., Shinoda, M., Hirose, M., and Chiba, Y.

Subjects
Electric Medical Chart, Resource Description Framework, Linked Open Data, Electric Dental Chart
Abstract

CARS 2015: Computer Assisted Radiology and Surgery -- Proceedings of the 29th International Congress and Exhibition, Barcelona, Spain, June 24 - 27, 2015

Published
2015

126. Role of Neuron-Glial Interaction Mediated by IL-1β in Ectopic Tooth Pain.

Author

Komiya, H., Shimizu, K., Noma, N., Tsuboi, Y., Honda, K., Kanno, K., Ohara, K., Shinoda, M., Ogiso, B., and Iwata, K.

Subjects
ECTOPIC tooth eruption, TOOTHACHE, FACIAL pain, ENDODONTICS, PULPITIS, REFERRED pain, HYPERALGESIA, CELL metabolism, ANIMAL experimentation, CAPSAICIN, CARRIER proteins, CELLULAR signal transduction, COMPARATIVE studies, CYTOSKELETAL proteins, DENTAL pulp diseases, ELECTROMYOGRAPHY, SENSORY ganglia, IMMUNOHISTOCHEMISTRY, INTERLEUKIN-1, RESEARCH methodology, MEDICAL cooperation, MEMBRANE proteins, NEURONS, RATS, RESEARCH, EVALUATION research
Abstract

Although many reports have demonstrated that ectopic pain develops in the orofacial region following tooth pulp inflammation, which often causes misdiagnosis and inappropriate treatment for patients with pulpitis, the precise mechanism remains unknown. In the present study, we hypothesized that the functional interaction between satellite glial cells and neurons mediated by interleukin 1β (IL-1β) in the trigeminal ganglion (TG) is involved in ectopic orofacial pain associated with tooth pulp inflammation. The digastric muscle electromyogram (D-EMG) activity elicited by capsaicin administration into the maxillary second molar tooth pulp was analyzed to evaluate the noxious reflex and was significantly increased in rats with inflammation of the maxillary first molar (M1) versus rats injected with saline. A significant increase in the expression of connexin43 (Cx43), a gap junction containing protein, was observed in activated satellite glial cells surrounding second molar-innervating neurons in the TG after M1 pulpitis. Daily administration of Gap26, a Cx43 mimetic peptide and inhibitor, in the TG significantly suppressed the enhancement of capsaicin-induced D-EMG activity and the percentage of Fluoro-Gold (FG)-labeled cells encircled by glial fibrillary acid protein-immunoreactive (IR) + Cx43-IR cells after M1 pulp inflammation ( P < 0.01). The percentage of FG-labeled cells encircled by glial fibrillary acid protein-IR + IL-1β-IR cells, IL-1 type I receptor-IR cells labeled with FG, and TRPV1-IR cells labeled with FG significantly increased after M1 pulp inflammation ( P < 0.01). Daily administration of IL-1ra, an IL-1 receptor antagonist, into the TG significantly reduced the enhancement of capsaicin-induced D-EMG activity and the percentage of TRPV1-IR neurons labeled with FG after M1 pulp inflammation ( P < 0.01). The present findings suggest that satellite glial cell is activated in the TG via activated gap junctions composed of Cx43 following tooth pulp inflammation, which leads to the hyperactivation of remote neurons via IL-1β mechanisms and results in ectopic tooth pulp pain in the adjacent tooth. [ABSTRACT FROM AUTHOR]

Published
2018
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129. P-136 De novo malignancy after living donor liver transplantation

Author

Shinoda, M., primary, Itano, O., additional, Obara, H., additional, Kitagoo, M., additional, Hibi, T., additional, Abe, Y., additional, Yagi, H., additional, Matsubara, K., additional, Yamada, Y., additional, Fujino, A., additional, Hoshino, K., additional, Kuroda, T., additional, and Kitagawa, Y., additional

Published
2015
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135. Effects of spatiotemporal heterogeneity of forage availability on annual range size of Mongolian gazelles.

Author

Imai, S., Ito, T. Y., Kinugasa, T., Shinoda, M., Tsunekawa, A., and Lhagvasuren, B.

Subjects
SPATIOTEMPORAL processes, MONGOLIAN gazelles, FORAGE, MAMMAL migration, ARTIFICIAL satellite tracking, HOME range (Animal geography), HETEROGENEITY
Abstract

We analyzed the effects of forage amount and its spatiotemporal heterogeneity on the annual range size of Mongolian gazelles by tracking 20 gazelles over a wide range of their distribution in Mongolia and by applying the normalized difference vegetation index ( NDVI). Annual ranges were separated into four regions. The maximum individual annual range size was more than 40 times the minimum (range: 900-37 000 km2). Annual range size was increased with increasing forage amount and spatial heterogeneity and seasonal change in forage amount. Many tracked gazelles changed their range locations between summer and winter, and these ranges occupied only small parts of their annual ranges. The smaller annual range size in the areas with smaller forage amount was explained by the smaller seasonal change and spatial heterogeneity of forage amount. Knowledge of such variations of movements and environments in a continuous distribution can improve our understanding of movement ecology. [ABSTRACT FROM AUTHOR]

Published
2017
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148. Programmed chemotherapy for patients with metastatic unresectable gastric cancer

Author

Shinoda, M, Ando, T, El-Omar, EM, Takashi, H, Suzuki, T, Murayama, M, Morise, K, Goto, H, Shinoda, M, Ando, T, El-Omar, EM, Takashi, H, Suzuki, T, Murayama, M, Morise, K, and Goto, H

Abstract

Background: Recent advances in the treatment of metastatic unresectable gastric cancers (MGC) include the development of new antitumor drugs and new regimens for their use. However, the selection of individually designed regimens by gastric cancer (GC) subtype remains problematic. Here, we investigated the clinical usefulness of programmed chemotherapy. Methodology/Principal Findings: MGC patients were classified into three groups by clinical condition. We implemented a chemotherapy program consisting of S-1 combination regimens. Median survival time (MST) of level 1 patients was 416 days (95% CI: 313-506 days), with an overall response rate of 47%. MSTs of level 2 and 3 patients were 208 (95% CI: 153-287 days) and 95 days (95% CI: 28-136 days), respectively. Grade 3-4 toxicities were neutropenia in 12% and anorexia in 6%. All treatment- related toxicities were resolved, and no treatment-related deaths occurred. Conclusions/Significance: This program provided reasonable selection of case-matching regimens and may improve the survival of patients with MGC. Further, it may represent the first clinical tool to provide efficient chemotherapy course selection for MGC. Ongoing analysis of newly developed drugs and regimens will allow the efficacy of this chemotherapy program to be improved. © 2012 Shinoda et al.

Published
2012

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