Search

Your search keyword '"Shah, Payal"' showing total 1,010 results
Start Over Author "Shah, Payal"
1,010 results on '"Shah, Payal"'

105. Acceptability of artificial intelligence-based retina screening in general population

Author

Shah, Payal, Mishra, Divyansh, Shanmugam, Mahesh, Vighnesh, M., and Jayaraj, Hariprasad

Subjects
Artificial intelligence -- Surveys -- Usage, Outpatients -- Surveys -- Psychological aspects, Eye -- Medical examination, Health attitudes -- Surveys, Retinal diseases -- Surveys -- Diagnosis, Artificial intelligence, Technology application, Health
Abstract

Byline: Payal. Shah, Divyansh. Mishra, Mahesh. Shanmugam, M. Vighnesh, Hariprasad. Jayaraj Purpose: A deep learning system (DLS) using artificial intelligence (AI) is emerging as a very promising technology in the [...]

Published
2022

110. TABLE 3 from Phase I Trial of Autologous RNA-electroporated cMET-directed CAR T Cells Administered Intravenously in Patients with Melanoma and Breast Carcinoma

Author

Shah, Payal D., primary, Huang, Alexander C., primary, Xu, Xiaowei, primary, Orlowski, Robert, primary, Amaravadi, Ravi K., primary, Schuchter, Lynn M., primary, Zhang, Paul, primary, Tchou, Julia, primary, Matlawski, Tina, primary, Cervini, Amanda, primary, Shea, Joanne, primary, Gilmore, Joan, primary, Lledo, Lester, primary, Dengel, Karen, primary, Marshall, Amy, primary, Wherry, E. John, primary, Linette, Gerald P., primary, Brennan, Andrea, primary, Gonzalez, Vanessa, primary, Kulikovskaya, Irina, primary, Lacey, Simon F., primary, Plesa, Gabriela, primary, June, Carl H., primary, Vonderheide, Robert H., primary, and Mitchell, Tara C., primary

Published
2023
Full Text
View/download PDF

111. Supplementary Figure 1 from Phase I Trial of Autologous RNA-electroporated cMET-directed CAR T Cells Administered Intravenously in Patients with Melanoma and Breast Carcinoma

Author

Shah, Payal D., primary, Huang, Alexander C., primary, Xu, Xiaowei, primary, Orlowski, Robert, primary, Amaravadi, Ravi K., primary, Schuchter, Lynn M., primary, Zhang, Paul, primary, Tchou, Julia, primary, Matlawski, Tina, primary, Cervini, Amanda, primary, Shea, Joanne, primary, Gilmore, Joan, primary, Lledo, Lester, primary, Dengel, Karen, primary, Marshall, Amy, primary, Wherry, E. John, primary, Linette, Gerald P., primary, Brennan, Andrea, primary, Gonzalez, Vanessa, primary, Kulikovskaya, Irina, primary, Lacey, Simon F., primary, Plesa, Gabriela, primary, June, Carl H., primary, Vonderheide, Robert H., primary, and Mitchell, Tara C., primary

Published
2023
Full Text
View/download PDF

112. Supplementary Figure 2 from Phase I Trial of Autologous RNA-electroporated cMET-directed CAR T Cells Administered Intravenously in Patients with Melanoma and Breast Carcinoma

Author

Shah, Payal D., primary, Huang, Alexander C., primary, Xu, Xiaowei, primary, Orlowski, Robert, primary, Amaravadi, Ravi K., primary, Schuchter, Lynn M., primary, Zhang, Paul, primary, Tchou, Julia, primary, Matlawski, Tina, primary, Cervini, Amanda, primary, Shea, Joanne, primary, Gilmore, Joan, primary, Lledo, Lester, primary, Dengel, Karen, primary, Marshall, Amy, primary, Wherry, E. John, primary, Linette, Gerald P., primary, Brennan, Andrea, primary, Gonzalez, Vanessa, primary, Kulikovskaya, Irina, primary, Lacey, Simon F., primary, Plesa, Gabriela, primary, June, Carl H., primary, Vonderheide, Robert H., primary, and Mitchell, Tara C., primary

Published
2023
Full Text
View/download PDF

113. FIGURE 2 from Phase I Trial of Autologous RNA-electroporated cMET-directed CAR T Cells Administered Intravenously in Patients with Melanoma and Breast Carcinoma

Author

Shah, Payal D., primary, Huang, Alexander C., primary, Xu, Xiaowei, primary, Orlowski, Robert, primary, Amaravadi, Ravi K., primary, Schuchter, Lynn M., primary, Zhang, Paul, primary, Tchou, Julia, primary, Matlawski, Tina, primary, Cervini, Amanda, primary, Shea, Joanne, primary, Gilmore, Joan, primary, Lledo, Lester, primary, Dengel, Karen, primary, Marshall, Amy, primary, Wherry, E. John, primary, Linette, Gerald P., primary, Brennan, Andrea, primary, Gonzalez, Vanessa, primary, Kulikovskaya, Irina, primary, Lacey, Simon F., primary, Plesa, Gabriela, primary, June, Carl H., primary, Vonderheide, Robert H., primary, and Mitchell, Tara C., primary

Published
2023
Full Text
View/download PDF

114. TABLE 2 from Phase I Trial of Autologous RNA-electroporated cMET-directed CAR T Cells Administered Intravenously in Patients with Melanoma and Breast Carcinoma

Author

Shah, Payal D., primary, Huang, Alexander C., primary, Xu, Xiaowei, primary, Orlowski, Robert, primary, Amaravadi, Ravi K., primary, Schuchter, Lynn M., primary, Zhang, Paul, primary, Tchou, Julia, primary, Matlawski, Tina, primary, Cervini, Amanda, primary, Shea, Joanne, primary, Gilmore, Joan, primary, Lledo, Lester, primary, Dengel, Karen, primary, Marshall, Amy, primary, Wherry, E. John, primary, Linette, Gerald P., primary, Brennan, Andrea, primary, Gonzalez, Vanessa, primary, Kulikovskaya, Irina, primary, Lacey, Simon F., primary, Plesa, Gabriela, primary, June, Carl H., primary, Vonderheide, Robert H., primary, and Mitchell, Tara C., primary

Published
2023
Full Text
View/download PDF

115. TABLE 4 from Phase I Trial of Autologous RNA-electroporated cMET-directed CAR T Cells Administered Intravenously in Patients with Melanoma and Breast Carcinoma

Author

Shah, Payal D., primary, Huang, Alexander C., primary, Xu, Xiaowei, primary, Orlowski, Robert, primary, Amaravadi, Ravi K., primary, Schuchter, Lynn M., primary, Zhang, Paul, primary, Tchou, Julia, primary, Matlawski, Tina, primary, Cervini, Amanda, primary, Shea, Joanne, primary, Gilmore, Joan, primary, Lledo, Lester, primary, Dengel, Karen, primary, Marshall, Amy, primary, Wherry, E. John, primary, Linette, Gerald P., primary, Brennan, Andrea, primary, Gonzalez, Vanessa, primary, Kulikovskaya, Irina, primary, Lacey, Simon F., primary, Plesa, Gabriela, primary, June, Carl H., primary, Vonderheide, Robert H., primary, and Mitchell, Tara C., primary

Published
2023
Full Text
View/download PDF

116. TABLE 5 from Phase I Trial of Autologous RNA-electroporated cMET-directed CAR T Cells Administered Intravenously in Patients with Melanoma and Breast Carcinoma

Author

Shah, Payal D., primary, Huang, Alexander C., primary, Xu, Xiaowei, primary, Orlowski, Robert, primary, Amaravadi, Ravi K., primary, Schuchter, Lynn M., primary, Zhang, Paul, primary, Tchou, Julia, primary, Matlawski, Tina, primary, Cervini, Amanda, primary, Shea, Joanne, primary, Gilmore, Joan, primary, Lledo, Lester, primary, Dengel, Karen, primary, Marshall, Amy, primary, Wherry, E. John, primary, Linette, Gerald P., primary, Brennan, Andrea, primary, Gonzalez, Vanessa, primary, Kulikovskaya, Irina, primary, Lacey, Simon F., primary, Plesa, Gabriela, primary, June, Carl H., primary, Vonderheide, Robert H., primary, and Mitchell, Tara C., primary

Published
2023
Full Text
View/download PDF

117. TABLE 1 from Phase I Trial of Autologous RNA-electroporated cMET-directed CAR T Cells Administered Intravenously in Patients with Melanoma and Breast Carcinoma

Author

Shah, Payal D., primary, Huang, Alexander C., primary, Xu, Xiaowei, primary, Orlowski, Robert, primary, Amaravadi, Ravi K., primary, Schuchter, Lynn M., primary, Zhang, Paul, primary, Tchou, Julia, primary, Matlawski, Tina, primary, Cervini, Amanda, primary, Shea, Joanne, primary, Gilmore, Joan, primary, Lledo, Lester, primary, Dengel, Karen, primary, Marshall, Amy, primary, Wherry, E. John, primary, Linette, Gerald P., primary, Brennan, Andrea, primary, Gonzalez, Vanessa, primary, Kulikovskaya, Irina, primary, Lacey, Simon F., primary, Plesa, Gabriela, primary, June, Carl H., primary, Vonderheide, Robert H., primary, and Mitchell, Tara C., primary

Published
2023
Full Text
View/download PDF

118. FIGURE 1 from Phase I Trial of Autologous RNA-electroporated cMET-directed CAR T Cells Administered Intravenously in Patients with Melanoma and Breast Carcinoma

Author

Shah, Payal D., primary, Huang, Alexander C., primary, Xu, Xiaowei, primary, Orlowski, Robert, primary, Amaravadi, Ravi K., primary, Schuchter, Lynn M., primary, Zhang, Paul, primary, Tchou, Julia, primary, Matlawski, Tina, primary, Cervini, Amanda, primary, Shea, Joanne, primary, Gilmore, Joan, primary, Lledo, Lester, primary, Dengel, Karen, primary, Marshall, Amy, primary, Wherry, E. John, primary, Linette, Gerald P., primary, Brennan, Andrea, primary, Gonzalez, Vanessa, primary, Kulikovskaya, Irina, primary, Lacey, Simon F., primary, Plesa, Gabriela, primary, June, Carl H., primary, Vonderheide, Robert H., primary, and Mitchell, Tara C., primary

Published
2023
Full Text
View/download PDF

119. Data from Phase I Trial of Autologous RNA-electroporated cMET-directed CAR T Cells Administered Intravenously in Patients with Melanoma and Breast Carcinoma

Author

Shah, Payal D., primary, Huang, Alexander C., primary, Xu, Xiaowei, primary, Orlowski, Robert, primary, Amaravadi, Ravi K., primary, Schuchter, Lynn M., primary, Zhang, Paul, primary, Tchou, Julia, primary, Matlawski, Tina, primary, Cervini, Amanda, primary, Shea, Joanne, primary, Gilmore, Joan, primary, Lledo, Lester, primary, Dengel, Karen, primary, Marshall, Amy, primary, Wherry, E. John, primary, Linette, Gerald P., primary, Brennan, Andrea, primary, Gonzalez, Vanessa, primary, Kulikovskaya, Irina, primary, Lacey, Simon F., primary, Plesa, Gabriela, primary, June, Carl H., primary, Vonderheide, Robert H., primary, and Mitchell, Tara C., primary

Published
2023
Full Text
View/download PDF

120. Combination ATR (ceralasertib) and PARP (olaparib) Inhibitor (CAPRI) Trial in Acquired PARP Inhibitor–Resistant Homologous Recombination–Deficient Ovarian Cancer

Author

Wethington, Stephanie L., primary, Shah, Payal D., additional, Martin, Lainie, additional, Tanyi, Janos L., additional, Latif, Nawar, additional, Morgan, Mark, additional, Torigian, Drew A., additional, Rodriguez, Diego, additional, Smith, Simon A., additional, Dean, Emma, additional, Domchek, Susan M., additional, Drapkin, Ronny, additional, Shih, Ie-Ming, additional, Brown, Eric J., additional, Hwang, Wei-Ting, additional, Armstrong, Deborah K., additional, Gaillard, Stephanie, additional, Giuntoli, Robert, additional, and Simpkins, Fiona, additional

Published
2023
Full Text
View/download PDF

121. Analytical validation of a multi-cancer early detection test with cancer signal origin using a cell-free DNA–based targeted methylation assay

Author

Alexander, Gregory E., primary, Lin, Wendy, additional, Ortega, Fabian E., additional, Ramaiah, Madhuvanthi, additional, Jung, Byoungsok, additional, Ji, Lijuan, additional, Revenkova, Ekaterina, additional, Shah, Payal, additional, Croisetiere, Christian, additional, Berman, Jennifer R., additional, Eubank, Lane, additional, Naik, Gunjan, additional, Brooks, Jacqueline, additional, Mich, Andrea, additional, Shojaee, Seyedmehdi, additional, Ronaghi, Neda, additional, Chawla, Hemanshi, additional, Hou, Xinyi, additional, Liu, Qinwen, additional, Yakym, Christopher-James A. V., additional, Moradi, Patriss Wais, additional, Halks-Miller, Meredith, additional, Aravanis, Alexander M., additional, Parpart-Li, Sonya, additional, and Hunkapiller, Nathan, additional

Published
2023
Full Text
View/download PDF

122. Supplementary Figure 2 from Phase I Trial of Autologous RNA-electroporated cMET-directed CAR T cells Administered Intravenously in Patients with Melanoma & Breast Carcinoma

Author

Shah, Payal D, primary, Huang, Alexander C., primary, Xu, Xiaowei, primary, Orlowski, Robert, primary, Amaravadi, Ravi K, primary, Schuchter, Lynn M., primary, Zhang, Paul, primary, Tchou, Julia, primary, Matlawski, Tina, primary, Cervini, Amanda, primary, Shea, Joanne, primary, Gilmore, Joan, primary, Lledo, Lester, primary, Dengel, Karen, primary, Marshall, Amy, primary, Wherry, E. John, primary, Linette, Gerald P, primary, Brennan, Andrea Lynne, primary, Gonzalez, Vanessa E, primary, Kulikovskaya, Irina, primary, Lacey, Simon F, primary, Plesa, Gabriela, primary, June, Carl H, primary, Vonderheide, Robert H, primary, and Mitchell, Tara C, primary

Published
2023
Full Text
View/download PDF

123. Supplementary Tables 1-3 from EUS-based Pancreatic Cancer Surveillance in BRCA1/BRCA2/PALB2/ATM Carriers Without a Family History of Pancreatic Cancer

Author

Katona, Bryson W., primary, Long, Jessica M., primary, Ahmad, Nuzhat A., primary, Attalla, Sara, primary, Bradbury, Angela R., primary, Carpenter, Erica L., primary, Clark, Dana F., primary, Constantino, Gillain, primary, Das, Koushik K., primary, Domchek, Susan M., primary, Dudzik, Christina, primary, Ebrahimzadeh, Jessica, primary, Ginsberg, Gregory G., primary, Heiman, Jordan, primary, Kochman, Michael L., primary, Maxwell, Kara N., primary, McKenna, Danielle B., primary, Powers, Jacquelyn, primary, Shah, Payal D., primary, Wangensteen, Kirk J., primary, and Rustgi, Anil K., primary

Published
2023
Full Text
View/download PDF

124. Supplementary Figure 1 from Phase I Trial of Autologous RNA-electroporated cMET-directed CAR T cells Administered Intravenously in Patients with Melanoma & Breast Carcinoma

Author

Shah, Payal D, primary, Huang, Alexander C., primary, Xu, Xiaowei, primary, Orlowski, Robert, primary, Amaravadi, Ravi K, primary, Schuchter, Lynn M., primary, Zhang, Paul, primary, Tchou, Julia, primary, Matlawski, Tina, primary, Cervini, Amanda, primary, Shea, Joanne, primary, Gilmore, Joan, primary, Lledo, Lester, primary, Dengel, Karen, primary, Marshall, Amy, primary, Wherry, E. John, primary, Linette, Gerald P, primary, Brennan, Andrea Lynne, primary, Gonzalez, Vanessa E, primary, Kulikovskaya, Irina, primary, Lacey, Simon F, primary, Plesa, Gabriela, primary, June, Carl H, primary, Vonderheide, Robert H, primary, and Mitchell, Tara C, primary

Published
2023
Full Text
View/download PDF

125. Data from Phase I Trial of Autologous RNA-electroporated cMET-directed CAR T cells Administered Intravenously in Patients with Melanoma & Breast Carcinoma

Author

Shah, Payal D, primary, Huang, Alexander C., primary, Xu, Xiaowei, primary, Orlowski, Robert, primary, Amaravadi, Ravi K, primary, Schuchter, Lynn M., primary, Zhang, Paul, primary, Tchou, Julia, primary, Matlawski, Tina, primary, Cervini, Amanda, primary, Shea, Joanne, primary, Gilmore, Joan, primary, Lledo, Lester, primary, Dengel, Karen, primary, Marshall, Amy, primary, Wherry, E. John, primary, Linette, Gerald P, primary, Brennan, Andrea Lynne, primary, Gonzalez, Vanessa E, primary, Kulikovskaya, Irina, primary, Lacey, Simon F, primary, Plesa, Gabriela, primary, June, Carl H, primary, Vonderheide, Robert H, primary, and Mitchell, Tara C, primary

Published
2023
Full Text
View/download PDF

126. Supplementary Data from A Phase I Study of Alpelisib in Combination with Trastuzumab and LJM716 in Patients with PIK3CA-Mutated HER2-Positive Metastatic Breast Cancer

Author

Jhaveri, Komal, primary, Drago, Joshua Z., primary, Shah, Payal Deepak, primary, Wang, Rui, primary, Pareja, Fresia, primary, Ratzon, Fanni, primary, Iasonos, Alexia, primary, Patil, Sujata, primary, Rosen, Neal, primary, Fornier, Monica N., primary, Sklarin, Nancy T., primary, Chandarlapaty, Sarat, primary, and Modi, Shanu, primary

Published
2023
Full Text
View/download PDF

128. Abstract P5-08-01: Pilot study of a patient-reported outcome (PRO) measurement strategy to determine impact of screening for minimal residual disease (MRD) in high-risk breast cancer survivors

Author

Kaufmann, Tara, primary, Chang, Patrick, additional, Rosenberg, Shoshana, additional, Frank, Elizabeth, additional, Hobbs, Brian, additional, Bayne, Lauren J., additional, Nivar, Isoris, additional, Goodspeed, Brooke L., additional, Rohn, Killian M., additional, Kugler, Emily M., additional, Fox, Kevin, additional, Domchek, Susan, additional, Bradbury, Angela, additional, Shah, Payal, additional, Knollman, Hayley, additional, Jankowitz, Rachel C., additional, Makhlin, Igor, additional, Clark, Amy S., additional, Chodosh, Lewis A., additional, DeMichele, Angela, additional, and Goodfellow, Katherine, additional

Published
2023
Full Text
View/download PDF

129. Abstract OT2-09-01: TBCRC-055: A Phase II Study of NirAparib, Dostarlimab, and Radiotherapy in Metastatic, PD-L1 Negative or Immunotherapy-Refractory Triple-Negative Breast Cancer (NADiR) – NCT04837209

Author

Scott, Elizabeth, primary, Isakoff, Steven J., additional, Taghian, Alphonse G., additional, Wright, Jean, additional, Santa-Maria, Cesar Augusto, additional, Shah, Payal, additional, Taunk, Neil, additional, Anders, Carey, additional, Blitzblau, Rachel, additional, Gupta, Gaorav, additional, and Ho, Alice, additional

Published
2023
Full Text
View/download PDF

131. Coats' disease - Prognostic factors for globe and vision salvage in children, a long-term experience

Author

Shanmugam, Mahesh, Shah, Payal, Sagar, Pradeep, Ramanjulu, Rajesh, and Mishra, Divyansh

Subjects
Vision disorders in children -- Prognosis -- Development and progression, Retinal diseases -- Prognosis -- Development and progression, Pediatric research, Health
Abstract

Byline: Mahesh. Shanmugam, Payal. Shah, Pradeep. Sagar, Rajesh. Ramanjulu, Divyansh. Mishra Purpose: Coats' disease is associated with poor outcomes, and there are limited studies on long-term outcomes of Coats' disease. [...]

Published
2022

134. Spaces to Speak: Photovoice and the Reimagination of Girls' Education in India

Author

Shah, Payal

Abstract

Delving into the "black box" of schooling can help us better understand the paradoxical reality that schooling for girls can be simultaneously empowering and disempowering. Despite recent interest in developing innovative research methodologies within the field of comparative education, there has been less attention to and reflexivity about the use of critical and participatory research methodologies as a way to gain insight into school processes that lead to dis/empowerment. This article details the use of photovoice methodology with rural, marginalized, adolescent-aged girls in Western India, with particular attention to collaboration, power sharing, and the production of "voice." Through a case study of a group of girls in Gujarat, this article illustrates how photovoice methodology can act as an important analytical heuristic to illuminate the relationship between schooling and girls' empowerment and how photovoice as a method might itself contribute to the empowerment process of girls.

Published
2015
Full Text
View/download PDF

143. Association of breast cancer risk in BRCA1 and BRCA2 mutation carriers with genetic variants showing differential allelic expression: identification of a modifier of breast cancer risk at locus 11q22.3

Author

Hamdi, Yosr, Soucy, Penny, Kuchenbaeker, Karoline B., Pastinen, Tomi, Droit, Arnaud, Lemaçon, Audrey, Adlard, Julian, Aittomäki, Kristiina, Andrulis, Irene L., Arason, Adalgeir, Arnold, Norbert, Arun, Banu K., Azzollini, Jacopo, Bane, Anita, Barjhoux, Laure, Barrowdale, Daniel, Benitez, Javier, Berthet, Pascaline, Blok, Marinus J., Bobolis, Kristie, Bonadona, Valérie, Bonanni, Bernardo, Bradbury, Angela R., Brewer, Carole, Buecher, Bruno, Buys, Saundra S., Caligo, Maria A., Chiquette, Jocelyne, Chung, Wendy K., Claes, Kathleen B. M., Daly, Mary B., Damiola, Francesca, Davidson, Rosemarie, De la Hoya, Miguel, De Leeneer, Kim, Diez, Orland, Ding, Yuan Chun, Dolcetti, Riccardo, Domchek, Susan M., Dorfling, Cecilia M., Eccles, Diana, Eeles, Ros, Einbeigi, Zakaria, Ejlertsen, Bent, Engel, Christoph, Gareth Evans, D., Feliubadalo, Lidia, Foretova, Lenka, Fostira, Florentia, Foulkes, William D., Fountzilas, George, Friedman, Eitan, Frost, Debra, Ganschow, Pamela, Ganz, Patricia A., Garber, Judy, Gayther, Simon A., Gerdes, Anne-Marie, Glendon, Gord, Godwin, Andrew K., Goldgar, David E., Greene, Mark H., Gronwald, Jacek, Hahnen, Eric, Hamann, Ute, Hansen, Thomas V. O., Hart, Steven, Hays, John L., Hogervorst, Frans B. L., Hulick, Peter J., Imyanitov, Evgeny N., Isaacs, Claudine, Izatt, Louise, Jakubowska, Anna, James, Paul, Janavicius, Ramunas, Jensen, Uffe Birk, John, Esther M., Joseph, Vijai, Just, Walter, Kaczmarek, Katarzyna, Karlan, Beth Y., Kets, Carolien M., Kirk, Judy, Kriege, Mieke, Laitman, Yael, Laurent, Maïté, Lazaro, Conxi, Leslie, Goska, Lester, Jenny, Lesueur, Fabienne, Liljegren, Annelie, Loman, Niklas, Loud, Jennifer T., Manoukian, Siranoush, Mariani, Milena, Mazoyer, Sylvie, McGuffog, Lesley, Meijers-Heijboer, Hanne E. J., Meindl, Alfons, Miller, Austin, Montagna, Marco, Mulligan, Anna Marie, Nathanson, Katherine L., Neuhausen, Susan L., Nevanlinna, Heli, Nussbaum, Robert L., Olah, Edith, Olopade, Olufunmilayo I., Ong, Kai-ren, Oosterwijk, Jan C., Osorio, Ana, Papi, Laura, Park, Sue Kyung, Pedersen, Inge Sokilde, Peissel, Bernard, Segura, Pedro Perez, Peterlongo, Paolo, Phelan, Catherine M., Radice, Paolo, Rantala, Johanna, Rappaport-Fuerhauser, Christine, Rennert, Gad, Richardson, Andrea, Robson, Mark, Rodriguez, Gustavo C., Rookus, Matti A., Schmutzler, Rita Katharina, Sevenet, Nicolas, Shah, Payal D., Singer, Christian F., Slavin, Thomas P., Snape, Katie, Sokolowska, Johanna, Sønderstrup, Ida Marie Heeholm, Southey, Melissa, Spurdle, Amanda B., Stadler, Zsofia, Stoppa-Lyonnet, Dominique, Sukiennicki, Grzegorz, Sutter, Christian, Tan, Yen, Tea, Muy-Kheng, Teixeira, Manuel R., Teulé, Alex, Teo, Soo-Hwang, Terry, Mary Beth, Thomassen, Mads, Tihomirova, Laima, Tischkowitz, Marc, Tognazzo, Silvia, Toland, Amanda Ewart, Tung, Nadine, van den Ouweland, Ans M. W., van der Luijt, Rob B., van Engelen, Klaartje, van Rensburg, Elizabeth J., Varon-Mateeva, Raymonda, Wappenschmidt, Barbara, Wijnen, Juul T., Rebbeck, Timothy, Chenevix-Trench, Georgia, Offit, Kenneth, Couch, Fergus J., Nord, Silje, Easton, Douglas F., Antoniou, Antonis C., Simard, Jacques, EMBRACE, GEMO Study Collaborators, HEBON, and KConFab Investigators

Published
2017
Full Text
View/download PDF

144. Creating Intentional Spaces for Sustainable Development in the Indian Trans-Himalaya: Reconceptualizing Globalization from Below

Author

Shah, Payal

Abstract

In an era of globalization, multifaceted and complex changes have increasingly interconnected geographically dispersed places. A central question of globalization studies concerns whether top-down forces of globalization are forging a global culture or whether processes of globalization from below are able to push back against homogenization by appropriating global forces rather than simply being overwhelmed by them. In this paper, I develop the concept of intentional spaces to show how ideas move globally and how local communities appropriate these ideas, revealing the actual practices that happen in the middle of top-down and bottom-up processes of globalization. I identify three types of "'intentional spaces"--physical, pedagogical, and ideological--to document the middle: where top down global forces meet local responses, and how these processes unfold. These intentional spaces enable processes of globalization from below, particularly the development of a mode of critical education that is both political and anti-hegemonic. This critical education empowers local people to adapt global/Western perspectives and influences to indigenous perspectives and practices, creating its own discourses of globalization. I use the context of the trans-Himalayan region of Ladakh to consider how national and international forces intersect with the local, and how local communities re-envision their participation in a modern, global economy.

Published
2014
Full Text
View/download PDF

145. Effectiveness of Kanna photoscreener in detecting amblyopia risk factors

Author

Murali, Kaushik, Krishna, Viswesh, Krishna, Vrishab, Kumari, B., Murthy, Sowmya Raveendra, Vidhya, C., and Shah, Payal

Subjects
Image processing -- Computer programs, Amblyopia -- Diagnosis -- Risk factors, Machine learning -- Usage, Computer-aided medical diagnosis -- Methods, Pediatric research, Image processing software, Health
Abstract

Byline: Kaushik. Murali, Viswesh. Krishna, Vrishab. Krishna, B. Kumari, Sowmya. Raveendra Murthy, C. Vidhya, Payal. Shah Purpose: Amblyopia is a significant public health problem. Photoscreeners have been shown to have [...]

Published
2021

146. Copy number variants as modifiers of breast cancer risk for BRCA1/BRCA2 pathogenic variant carriers

Author

Hakkaart, Christopher, Pearson, John F., Marquart, Louise, Dennis, Joe, Wiggins, George A. R., Barnes, Daniel R., Robinson, Bridget A., Mace, Peter D., Aittomäki, Kristiina, Andrulis, Irene L., Arun, Banu K., Azzollini, Jacopo, Balmaña, Judith, Barkardottir, Rosa B., Belhadj, Sami, Berger, Lieke, Blok, Marinus J., Boonen, Susanne E., Borde, Julika, Bradbury, Angela R., Brunet, Joan, Buys, Saundra S., Caligo, Maria A., Campbell, Ian, Chung, Wendy K., Claes, Kathleen, Collonge-Rame, Marie-Agnès, Cook, Jackie, Cosgrove, Casey, Couch, Fergus J., Daly, Mary B., Dandiker, Sita, Davidson, Rosemarie, de la Hoya, Miguel, de Putter, Robin, Delnatte, Capucine, Dhawan, Mallika, Diez, Orland, Ding, Yuan Chun, Domchek, Susan M., Donaldson, Alan, Eason, Jacqueline, Easton, Douglas F., Ehrencrona, Hans, Engel, Christoph, Evans, D. Gareth, Faust, Ulrike, Feliubadaló, Lidia, Fostira, Florentia, Friedman, Eitan, Frone, Megan, Frost, Debra, Garber, Judy, Gayther, Simon A., Gehrig, Andrea, Gesta, Paul, Godwin, Andrew K., Goldgar, David E., Greene, Mark H., Hahnen, Eric, Hake, Christopher R., Hamann, Ute, Hansen, Thomas V. O., Hauke, Jan, Hentschel, Julia, Herold, Natalie, Honisch, Ellen, Hulick, Peter J., Imyanitov, Evgeny N., van Engelen, Klaartje, Wevers, Marijke R., Isaacs, Claudine, Izatt, Louise, Izquierdo, Angel, Jakubowska, Anna, James, Paul A., Janavicius, Ramunas, John, Esther M., Joseph, Vijai, Karlan, Beth Y., Kemp, Zoe, Kirk, Judy, Konstantopoulou, Irene, Koudijs, Marco, Kwong, Ava, Laitman, Yael, Lalloo, Fiona, Lasset, Christine, Lautrup, Charlotte, Lazaro, Conxi, Legrand, Clémentine, Leslie, Goska, Lesueur, Fabienne, Mai, Phuong L., Manoukian, Siranoush, Mari, Véronique, Martens, John W. M., McGuffog, Lesley, Mebirouk, Noura, Meindl, Alfons, Miller, Austin, Montagna, Marco, Moserle, Lidia, Mouret-Fourme, Emmanuelle, Musgrave, Hannah, Nambot, Sophie, Nathanson, Katherine L., Neuhausen, Susan L., Nevanlinna, Heli, Yie, Joanne Ngeow Yuen, Nguyen-Dumont, Tu, Nikitina-Zake, Liene, Offit, Kenneth, Olah, Edith, Olopade, Olufunmilayo I., Osorio, Ana, Ott, Claus-Eric, Park, Sue K., Parsons, Michael T., Pedersen, Inge Sokilde, Peixoto, Ana, Perez-Segura, Pedro, Peterlongo, Paolo, Pocza, Timea, Radice, Paolo, Ramser, Juliane, Rantala, Johanna, Rodriguez, Gustavo C., Rønlund, Karina, Rosenberg, Efraim H., Rossing, Maria, Schmutzler, Rita K., Shah, Payal D., Sharif, Saba, Sharma, Priyanka, Side, Lucy E., Simard, Jacques, Singer, Christian F., Snape, Katie, Steinemann, Doris, Stoppa-Lyonnet, Dominique, Sutter, Christian, Tan, Yen Yen, Teixeira, Manuel R., Teo, Soo Hwang, Thomassen, Mads, Thull, Darcy L., Tischkowitz, Marc, Toland, Amanda E., Trainer, Alison H., Tripathi, Vishakha, Tung, Nadine, van Rensburg, Elizabeth J., Vega, Ana, Viel, Alessandra, Walker, Lisa, Weitzel, Jeffrey N., Wevers, Marike R., Chenevix-Trench, Georgia, Spurdle, Amanda B., Antoniou, Antonis C., Walker, Logan C., MUMC+: DA KG Lab Specialisten (9), RS: GROW - R4 - Reproductive and Perinatal Medicine, Institut Català de la Salut, [Hakkaart C, Pearson JF, Wiggins GAR] Department of Pathology and Biomedical Science, University of Otago, Christchurch, New Zealand. [Marquart L] QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia. School of Public Health, University of Queensland, Brisbane, Australia. [Dennis J, Barnes DR] Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK. [Balmaña J] Hereditary cancer Genetics Group, Vall d’Hebron Institute of Oncology (VHIO), Barcelona, Spain. Servei d’Oncologia Mèdica, Vall d’Hebron Hospital Universitari, Barcelona, Spain. [Diez O] Hereditary cancer Genetics Group, Vall d’Hebron Institute of Oncology (VHIO), Barcelona, Spain. Vall d’Hebron Hospital Universitari, Barcelona, Spain. Àrea de Genètica Clínica i Molecular, Vall d’Hebron Hospital Universitari, Barcelona, Spain, Vall d'Hebron Barcelona Hospital Campus, Medicum, Research Programs Unit, Kristiina Aittomäki / Principal Investigator, HUSLAB, Clinicum, Department of Obstetrics and Gynecology, HUS Gynecology and Obstetrics, Pediatrics, Human genetics, Cancer Center Amsterdam, Faculteit Medische Wetenschappen/UMCG, and Medical Oncology

Subjects
Estrogen-metabolizing enzymes, Heterozygote, DNA Copy Number Variations, Neoplasms::Neoplasms by Site::Breast Neoplasms [DISEASES], Messenger, Genetic Phenomena::Genotype::Genetic Predisposition to Disease [PHENOMENA AND PROCESSES], Medicine (miscellaneous), Expression, Genetics and Molecular Biology, Breast Neoplasms, Breast Neoplasms/genetics, Genetic polymorphisms, Genetic Phenomena::Genetic Variation::Polymorphism, Genetic::Genomic Structural Variation::DNA Copy Number Variations [PHENOMENA AND PROCESSES], General Biochemistry, Genetics and Molecular Biology, Dna-adducts, Association, Mama - Càncer - Propensió, SDG 3 - Good Health and Well-being, Other subheadings::Other subheadings::/genetics [Other subheadings], Medicine and Health Sciences, Humans, Genetic Predisposition to Disease, Familial breast, RNA, Messenger, fenómenos genéticos::variación genética::polimorfismo genético::variación estructural genómica::variaciones del número de copias de ADN [FENÓMENOS Y PROCESOS], fenómenos genéticos::genotipo::predisposición genética a la enfermedad [FENÓMENOS Y PROCESOS], BRCA2 Protein, neoplasias::neoplasias por localización::neoplasias de la mama [ENFERMEDADES], Otros calificadores::Otros calificadores::/genética [Otros calificadores], BRCA1 Protein, Isoform 1a1 sult1a1, Sulfotransferase, BRCA2 Protein/genetics, Genòmica, Ovarian, General Biochemistry, Mama - Càncer - Aspectes genètics, RNA, BRCA1 Protein/genetics, Female, 3111 Biomedicine, General Agricultural and Biological Sciences, Brca1
Abstract

The contribution of germline copy number variants (CNVs) to risk of developing cancer in individuals with pathogenic BRCA1 or BRCA2 variants remains relatively unknown. We conducted the largest genome-wide analysis of CNVs in 15,342 BRCA1 and 10,740 BRCA2 pathogenic variant carriers. We used these results to prioritise a candidate breast cancer risk-modifier gene for laboratory analysis and biological validation. Notably, the HR for deletions in BRCA1 suggested an elevated breast cancer risk estimate (hazard ratio (HR) = 1.21), 95% confidence interval (95% CI = 1.09–1.35) compared with non-CNV pathogenic variants. In contrast, deletions overlapping SULT1A1 suggested a decreased breast cancer risk (HR = 0.73, 95% CI 0.59-0.91) in BRCA1 pathogenic variant carriers. Functional analyses of SULT1A1 showed that reduced mRNA expression in pathogenic BRCA1 variant cells was associated with reduced cellular proliferation and reduced DNA damage after treatment with DNA damaging agents. These data provide evidence that deleterious variants in BRCA1 plus SULT1A1 deletions contribute to variable breast cancer risk in BRCA1 carriers.

Published
2022

150. 644 Major pathologic response after a single radiotherapy fraction + a single pembrolizumab dose given preoperatively in patients with cT1N0 triple negative breast cancer (TNBC) – preliminary results of a phase 1b/2 study (NCT04454528)

Author

Tchou, Julia, primary, Clark, Amy, additional, Taunk, Neil, additional, Freedman, Gary, additional, Xu, Nucleus, additional, Minn, Andy, additional, Bradbury, Angela, additional, Gross, Angela Demichele, additional, Domchek, Susan, additional, Knollman, Hayley, additional, Jankowitz, Rachel, additional, Shah, Payal, additional, Fayanju, Oluwadamilola, additional, Nayak, Anupma, additional, Fraietta, Joseph, additional, and Huang, Alexander, additional

Published
2022
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results