111 results on '"Sang Cheol Cho"'
Search Results
102. TCT-718 Statin Is More Effective in Acute Myocardial Infarction Patients Presenting Atrial Fibrillation with High Level of High Sensitivity C-Reactive Protein Than Those with Low Level
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Myung Ho Jeong, Ju Han Kim, Jong Hyun Yoo, Young Jo Kim, Young Joon Hong, Myeong Chan Cho, Ji Eun Song, Youngkeun Ahn, Shung Chull Chae, Jei Keon Chae, Jae Yeong Cho, Chong Jin Kim, Su Young Jang, Sang Cheol Cho, and Hae Chang Jeong
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medicine.medical_specialty ,Statin ,biology ,business.industry ,medicine.drug_class ,C-reactive protein ,Atrial fibrillation ,Mean age ,medicine.disease ,Internal medicine ,biology.protein ,Cardiology ,Medicine ,cardiovascular diseases ,Statin therapy ,Myocardial infarction ,Cardiology and Cardiovascular Medicine ,business - Abstract
We investigated whether statin therapy and high-sensitivity C-reactive protein (hs-CRP) levels were associated with long term clinical outcomes in acute myocardial infarction (AMI) patients presenting atrial fibrillation (AF). 852 AMI patients (mean age = 70.3 ± 12.2 years, 565 males) who were
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- 2012
103. Stress-Induced Cardiomyopathy Presenting as Ventricular Tachycardia
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Chung Su Park, Sun Ho Hwang, Sang Cheol Cho, Weon Kim, Sang-Hyun Park, Wan Kim, and An Doc Jung
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medicine.medical_specialty ,medicine.diagnostic_test ,business.industry ,medicine.medical_treatment ,Cardiomyopathy ,medicine.disease ,Amiodarone ,Cardioversion ,Ventricular tachycardia ,Tachycardia, ventricular ,Broken heart syndrome ,Internal medicine ,Ventricular fibrillation ,medicine ,Cardiology ,Takotsubo cardiomyopathy ,Myocardial infarction ,business ,Letter to the Editor ,Electrocardiography ,medicine.drug - Abstract
To the Editor, Stress-induced cardiomyopathy (SIC) (also known as ampulla cardiomyopathy, tako-tsubo syndrome, and broken heart syndrome) mimicking an acute myocardial infarction is a unique acute cardiac syndrome that appears under physically or emotionally stressful circumstances. It was first described in Japan and is typically characterized by chest pain, elevated ST-segment on electrocardiography (ECG), mildly elevated cardiac enzymes, and reversible left-ventricular dysfunction [1]. Two-dimensional echocardiography (2D-Echo) reveals a typical regional wall motion abnormality; however, coronary angiography (CAG) usually shows no significant atherosclerotic stenosis. A left ventriculogram typically reveals akinesis of the mid-ventricle and apex and hyperkinesis of the base of the heart [1]. However, the mechanism or pathophysiology remains incompletely understood. In a study in Japan, approximately 9% of 88 patients were diagnosed with SIC associated with ventricular tachycardia (VT) or ventricular fibrillation (VF) during the clinical course [1], whereas in Korea, only one of 18 patients and three of 155 patients had VT or VF-associated SIC [2,3]. We report a case of SIC presenting as VT as an initial manifestation after extreme emotional stress. A 74-year-old woman with no risk factors of atherosclerosis presented to the emergency room with chest discomfort and general weakness that had begun 30 minutes prior to arrival. Chest discomfort developed when she experienced intense emotional stress after a severe quarrel with her sister-in-law; it was said that she did not have a good relationship with this individual. Her clinical signs were blood pressure (BP), 90/50 mmHg; heart rate (HR), 62 beats/min (bpm); respiratory rate, 20/min; and body temperature, 36℃. Nausea, chills, and generalized rigidity suddenly developed while her medical history was being taken. Her 12-lead ECG then showed VT, and HR was 217 bpm (Fig. 1A). VT was refractory to 200 J and 300 J of direct current (DC) cardioversion with an intravenous infusion of lidocaine and amiodarone. Her BP was sustained at 90/60 mmHg, and her mental status was alert. A few minutes later, ECG showed sinus arrhythmia (HR, 60 to 70 bpm), ST-segment depression, and T-wave inversion in leads II, III, avF, and V2-V6 (Fig. 1B). Chest X-ray findings were cardiomegaly (CT ratio, 0.65) and pulmonary congestion. The levels of serum creatinine kinase-MB (3.0 ng/mL) and troponin-I (0.16 ng/mL) were within normal limits. However, levels of serum myoglobin (220.2 ng/mL), high-sensitivity C-reactive protein (2.330 mg/L), and plasma N-terminal pro-brain natriuretic peptide (2,140 pg/mL) were elevated. 2D-Echo revealed an ejection fraction of 56%, with akinesis of the left ventricular apex and apical ballooning (Fig. 2A). On the second day of admission, CAG showed no significant stenosis, and left ventriculogram revealed apical ballooning and akinesis of the left ventricular apex (Fig. 3). The patient was treated with aspirin, amiodarone, and ramipril. A follow-up ECG on the second day showed a normal sinus rhythm (HR, 65 bpm) and normalized ST-segment and T-wave. After discharge, a follow-up 2D-Echo was performed every month. Akinesis of the left ventricular apex had recovered 5 months later (Fig. 2B). Figure 1 (A) Electrocardiography reveals ventricular tachycardia. (B) After infusion of intravenous lidocaine and amiodarone, electrocardiography reveals sinus arrhythmia and mild ST depression and T-wave inversion in lead II, III, aVF and V2-6. Figure 2 (A) Two dimensional echocardiography at admission shows apical akinesis and ballooning. (B) Follow-up two dimensional echocardiography after 5 months shows improvement of apical wall motion. Figure 3 Ventriculogram. (A) End-diastole. (B) End-systole. Left ventriculogram reveals apical akinesis and ballooning. SIC was first described in Japan in 1990 and is characterized by akinesis and ballooning of the left ventricular apex, similar to a Japanese octopus trap (tako-tsubo). Indeed, this is how this disease got its name, tako-tsubo cardiomyopathy, or ampulla cardiomyopathy. Also, Tsuchihashi et al. [1] referred to this disease as transient left ventricular apical ballooning. Recently, in Korea, Lee et al. [2] and Kim et al. [4] reported SIC presenting as transient akinesis of the mid-ventricle. They referred to this as acute regional cardiomyopathy rather than apical ballooning [2,4]. The pathophysiology of SIC is not clearly understood. Previous studies suggested that a surge of catecholamines in response to extreme physical or emotional stress, coronary spasm, elevated sympathetic tone, and pheochromocytoma are all related to SIC. Additional studies using contrast echocardiography or myocardial single photon emission computed tomography (M-SPECT) suggest that coronary microvascular dysfunction is related to SIC. Among 18 Korean patients with SIC [2], one showed akinesis of the mid-ventricle rather than the apex. Another patient (5.5%) suffered VT and VF during the clinical course and recovered after DC cardioversion. In a retrospective, multicenter study by Jo et al. [3], three of 155 patients had VT associated with SIC. In Japan, a retrospective, multicenter study involving 88 Japanese patients with SIC [1] reported that 9% of them experienced VT or VF. In our case, VT was the initial manifestation of SIC triggered by extreme emotional stress, and it recovered after intravenous injection of lidocaine and amiodarone. Wall-motion abnormality in SIC patients usually improves within 4 weeks. However, in our case, wall-motion abnormality improved 5 months later. Jo et al. [3] reported that predictors of the recovery of wall-motion index were an absence of arrhythmic events and elevated initial LV end-systolic diameter. However, generalization is limited, as the number of VT patients in that study was too small. In hibernating myocardium, delayed recovery would be expected if the morphologic changes were severe [5]. In our patient, we suggest that chronic and repeated emotional stress provoked morphologic changes in the myocardium, such as hibernating myocardium, that resulted in delayed recovery. Accordingly, recovery of wall-motion abnormality might be delayed. Further prospective trials should be undertaken to determine the mechanism and pathophysiology of SIC.
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- 2012
104. The Effect of Telmisartan on Endothelial Function and Arterial Stiffness in Patients With Essential Hypertension
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Sang Cheol Cho, Wan Kim, Jeong Su Park, Weon Kim, An Doc Jung, Sun Ho Hwang, Sang Hyun Park, and Sung Bum Hong
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Angiotensin II type 1 receptor blockers ,Endothelium, vascular ,medicine.medical_specialty ,Arteriosclerosis ,business.industry ,Essential hypertension ,medicine.disease ,Endocrinology ,Blood pressure ,Internal medicine ,Internal Medicine ,medicine ,Arterial stiffness ,Cardiology ,Original Article ,Telmisartan ,Cardiology and Cardiovascular Medicine ,Receptor ,business ,Pulse wave velocity ,Homeostasis ,medicine.drug - Abstract
Background and Objectives: Several studies have shown that angiotensin II receptor blockers (ARBs) improve endothelial function and arterial stiffness. Telmisartan is a highly selective ARB that activates peroxisome proliferator-activated receptor γ (PPARγ). The purpose of this study was to evaluate the effects of telmisartan, such as endothelial function, arterial stiffness, and insulin sensitivity, in patients with essential hypertension. Subjects and Methods: Thirty-nine patients with essential hypertension were administered telmisartan (80 mg once daily) using an open-labeled and prospective protocol. The patients were examined before and 8 weeks after treatment to assess changes in flow mediated-vasodilation (FMD), pulse wave velocity (PWV), quantitative insulin-sensitivity check index (QUICKI), homeostasis model assessment (HOMA), and adiponection. Results: The systolic and diastolic blood pressure (BP) decreased from 153±15 mmHg and 90±13 mmHg to 137±16 mmHg and 84±10 mmHg after telmisartan treatment, respectively (p
- Published
- 2009
105. The CHA2DS2VASc score can be used to stratify the prognosis of acute myocardial infarction patients irrespective of presence of atrial fibrillation.
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Kyung Hwan Kim, Wan Kim, Sun Ho Hwang, Won Yu Kang, Sang Cheol Cho, Weon Kim, and Myung Ho Jeong
- Abstract
Background: The CHA
2 DS2 VASc score has been used to evaluate the risk of thromboembolic events in atrial fibrillation. However, because all the components of CHA2 DS2 VASc are important cardiovascular risk factors, we decided to evaluate the effectiveness of CHA2 DS2 VASc score as a long-term predictor for prognosis in acute myocardial infarction (AMI) patients. Methods: We enrolled 15,681 AMI patients for the Korean Working Group in Acute Myocardial Infarction (KORMI) consecutively and analyzed retrospectively. We divided the all the patients into four groups according to CHADS2VASc score (Group I: 0-1, n = 3317; Group II: 2-3, n = 6794; Group 111: 4-5, n = 4457; Group IV: 6-9, n = 1113). The cardiac event was defined as the sum of all-cause mortality and recurrence of myocardial infarction. Results: As the risk score increased, the incidence of cardiac events was higher at 1,6,12, and 24 months. The cardiac event-free survival rate was lower as the risk score increased (Group I vs Group II, p < 0.001 ; Group II vs Group III, p < 0.001 ; Group III vs Group IV, p = 0.037). After adjusting confounding variables, the Cox-regression multivariate analysis showed that the CHA2 DS2 VASc score was an independent predictor for the long-term prognosis in total AMI patients (p < 0.001, hazard ratio = 1.414 per scale). Conclusion: The AMI patients with higher CHA2 DS2 VASc score had worse cardiovascular outcome. Therefore, CHADS2VASc score can be used to stratify AMI patients according to long-term prognosis irrespective of presence of atrial fibrillation. [ABSTRACT FROM AUTHOR]- Published
- 2015
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106. A Case of Secondary Gastric Tuberculosis Mimicking Submucosal Tumor
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Young Ho Seo, Sang Cheol Cho, Sang Hyun Park, So Young Ju, Jung Su Park, Hyang Mi Ko, Cheol Ju Park, Nam Hun Lee, Jun Seok Ko, An Doc Jung, and Bong Kyu Lee
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Pathology ,medicine.medical_specialty ,Tuberculosis ,business.industry ,Submucosal tumor ,General Engineering ,Medicine ,Ultrasonography ,business ,medicine.disease - Published
- 2008
107. Postimplantation Syndrome After Endovascular Aortic Aneurysm Repair in an Elderly Patient.
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Hong Ju An, Won Yu Kang, Chung Kang, Dong In Nam, Il Hyung Jung, Hoon Kang, Sang Sun Lee, Ho Yeong Song, Sang Cheol Cho, Sun Ho Hwang, and Wan Kim
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AORTIC aneurysm treatment ,SURGICAL stents ,VASCULAR grafts ,C-reactive protein ,LEUCOCYTOSIS ,BLOOD coagulation - Abstract
Endovascular procedures have been proposed as minimally invasive alternative treatments, allowing safe and effective aortic aneurysm repair. Despite the potential benefits, endovascular stent grafting may elicit an unexpected systemic inflammatory response, called postimplantation syndrome (PIS). The main features of PIS include fever, elevated C-reactive protein levels, leukocytosis and/or coagulation disturbances, perigraft air on abdominal computed tomography, and no evidence of infection. The main management of PIS is supportive care. Antibiotics have no clinical benefit. We report a case of PIS after endovascular aortic aneurysm repair in an elderly patient. [ABSTRACT FROM AUTHOR]
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- 2014
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108. Clinical outcomes of everolimus- and zotarolimus-eluting stents in patients with acute myocardial infarction for small coronary artery disease.
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Sang Cheol Cho, Myung Ho Jeong, Wan Kim, Youngkeun Ahn, Youngjoon Hong, Youngjo Kim, Chongjin Kim, Myeong Chan Cho, Kyoo Rok Han, and Hyo Soo Kim
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Background and purpose: There were limited data about comparison of zotarolimus-eluting stents (ZES) and everolimus-eluting stents (EES) in patients with small coronary artery disease (CAD), especially in patients with acute myocardial infarction (AMI). The objective of this study was to compare the clinical outcomes of ZES and EES in patients with AMI for small CAD. Methods and subjects: A total 1565 AMI patients treated with Endeavor-ZES (n = 651 ) (Medtronic Cardio-vascular, Santa Rosa, CA, USA) or Xience V/Promus-EES (n = 914) (Abbott Vascular, Temecula, CA/Boston Scientific, Natick, MA, USA) for small CAD (stent diameter <2.75 mm) in KAMIR (Korea Acute Myocardial Infarction Registry ) were enrolled. After propensity score matching to adjust for baseline clinical and angi-ographic characteristics, we compared a total 1302 patients (651 ZES and 651 EES) about major adverse cardiac events (MACE) at 1-year. Subgroup analysis about 1-year clinical outcomes was undertaken in patients who were discharged alive. Results: Baseline clinical and angiographic characteristics were similar between the two groups after propensity score matching. Total MACE did not differ between the two groups before (9.8% vs. 8.2%, p = 0.265) and after (9.8% vs. 9.4%, p = 0.778) propensity score matching. The EES group showed lower rate of 1-year cardiac death (5.4% vs. 3.3%, p = 0.041), target lesion failure (TLF; 6.9% vs. 4.3%, p = 0.022), and stent thrombosis (1.4% vs. 0.4%, p = 0.042) compared with the ZES group. However, there were no differences in 1-year cardiac death, TLF, and stent thrombosis in propensity score matched populations. Other various 1 -year clinical outcomes showed no difference between the two groups. Subgroup analysis in patients who were discharged alive showed similar outcomes between the two groups at 1 -year follow-up. Conclusion: In-this propensity score matched analysis, EES and ZES showed no significant difference in clinical outcomes at 1-year follow-up in patients with AMI for small CAD. [ABSTRACT FROM AUTHOR]
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- 2014
- Full Text
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109. EFFECT OF ONION PEEL EXTRACT ON ENDOTHELIAL FUNCTION AND ENDOTHELIAL PROGENITOR CELLS IN OVERWEIGHT AND OBESE SUBJECTS
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Sang Cheol Cho, Weon Kim, Hyun Soo Kim, Sun Ho Hwang, Wan Kim, and Jong Shin Woo
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chemistry.chemical_classification ,medicine.medical_specialty ,Antioxidant ,business.industry ,medicine.medical_treatment ,fungi ,Flavonoid ,food and beverages ,Overweight ,chemistry.chemical_compound ,Endocrinology ,chemistry ,Internal medicine ,medicine ,cardiovascular system ,heterocyclic compounds ,Obese subjects ,Progenitor cell ,medicine.symptom ,Quercetin ,business ,Cardiology and Cardiovascular Medicine ,Function (biology) - Abstract
Acute or chronic intake of polyphenol-rich foods has been reported to improve endothelial function. Quercetin, found abundantly in onion, is a potent antioxidant flavonoid. This study was designed to investigate whether consumption of onion peel extract (OPE) improves endothelial function in healthy
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110. TCT-377 Impact of New-Onset Acute Heart Failure in Patients with Acute Myocardial infarction Underwent Successful Revascularization
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Jong Hyun Yoo, Myung Ho Jeong, Seung-Woon Rha, Young Jo Kim, Keun-Ho Park, Youngkeun Ahn, Yangsoo Jang, and Sang Cheol Cho
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medicine.medical_specialty ,business.industry ,medicine.medical_treatment ,Revascularization ,medicine.disease ,humanities ,New onset ,Heart failure ,Internal medicine ,medicine ,Cardiology ,cardiovascular system ,In patient ,Myocardial infarction ,Cardiology and Cardiovascular Medicine ,business - Full Text
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111. TCT-267 Comparison of Coronary Plaque Components between Non-Culprit Lesion in Patients with Acute Coronary Syndrome and Target Lesion in Patients with Stable Angina: Virtual Histology-Intravascular Ultrasound Analysis
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Keun Ho Park, Ju Han Kim, Jong Hyun Yoo, Jeong Gwan Cho, Myung Ho Jeong, Sang Cheol Cho, Ji Eun Song, Jong Chun Park, Soo Young Park, Jung Chaee Kang, Young Joon Hong, Youngkeun Ahn, Doo Sun Sim, Hae Chang Jeong, Jae Yeong Cho, Yun Ha Choi, and Su Young Jang
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Target lesion ,medicine.medical_specialty ,Acute coronary syndrome ,business.industry ,medicine.disease ,Stable angina ,Virtual histology intravascular ultrasound ,Internal medicine ,Coronary plaque ,Culprit lesion ,medicine ,Cardiology ,cardiovascular system ,In patient ,Radiology ,business ,Cardiology and Cardiovascular Medicine - Full Text
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