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101. Physiological And Thermoregulatory Responses Of Body Cooling During Cycling In A Hot Environment

Author: John S. Navarro, Margaret C. Morrissey, Erin E. Dierickx, and Douglas J. Casa
Subjects: Physical Therapy, Sports Therapy and Rehabilitation, Orthopedics and Sports Medicine
Published: 2022

102. Microstructure of minerals and yerba mate extract co-crystallized with sucrose

Author: Deladino, Lorena, S. Navarro, Alba, and N. Martino, Miriam
Published: 2010
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103. Biomimetic Tubular Scaffold with Heparin Conjugation for Rapid Degradation in in situ Regeneration of a Small Diameter Neoartery

Author: Longtan Jiang, Yang Ouyang, Zhiyong Liu, Ying Yang, Jiawen Luo, Peter X. Ma, Kenichi Kuroda, Bo Yang, Ping Qiu, Y. Eugene Chen, and Renato S. Navarro
Subjects: Polyesters, Biophysics, Nanofibers, Lumen (anatomy), Bioengineering, 02 engineering and technology, Article, Biomaterials, Extracellular matrix, 03 medical and health sciences, Biomimetics, medicine, Animals, Regeneration, 030304 developmental biology, chemistry.chemical_classification, 0303 health sciences, Tissue Engineering, Tissue Scaffolds, Chemistry, Heparin, Regeneration (biology), Polymer, 021001 nanoscience & nanotechnology, medicine.disease, Blood Vessel Prosthesis, Rats, Cellular infiltration, medicine.anatomical_structure, Mechanics of Materials, Ceramics and Composites, Click chemistry, 0210 nano-technology, Biomedical engineering, Blood vessel, medicine.drug
Abstract: To address the clinical need for readily available small diameter vascular grafts, biomimetic tubular scaffolds were developed for rapid in situ blood vessel regeneration. The tubular scaffolds were designed to have an inner layer that is porous, interconnected, and with a nanofibrous architecture, which provided an excellent microenvironment for host cell invasion and proliferation. Through the synthesis of poly(spirolactic-co-lactic acid) (PSLA), a highly functional polymer with a norbornene substituting a methyl group in poly(l-lactic acid) (PLLA), we were able to covalently attach biomolecules onto the polymer backbone via thiol-ene click chemistry to impart desirable functionalities to the tubular scaffolds. Specifically, heparin was conjugated on the scaffolds in order to prevent thrombosis when implanted in situ. By controlling the amount of covalently attached heparin we were able to modulate the physical properties of the tubular scaffold, resulting in tunable wettability and degradation rate while retaining the porous and nanofibrous morphology. The scaffolds were successfully tested as rat abdominal aortic replacements. Patency and viability were confirmed through dynamic ultrasound and histological analysis of the regenerated tissue. The harvested tissue showed excellent vascular cellular infiltration, proliferation, and migration with laminar cellular arrangement. Furthermore, we achieved both complete reendothelialization of the vessel lumen and native-like media extracellular matrix. No signs of aneurysm or hyperplasia were observed after 3 months of vessel replacement. Taken together, we have developed an effective vascular graft able to generate small diameter blood vessels that can function in a rat model.
Published: 2021

104. The long‐noncoding RNA from the MYH7b locus (lncMYH7b) has pronounced effects on cardiomyocyte molecular and cellular phenotypes

Author: Lindsey J. Broadwell, Jose S. Navarro-Arriola, Rusty L. Montgomery, Leslie A. Leinwand, Kevin Rigby, Massimo Buvoli, John L. Rinn, and Michael J. Smallegan
Subjects: Genetics, Locus (genetics), Biology, Molecular Biology, Biochemistry, Phenotype, Long non-coding RNA, Biotechnology
Published: 2021

105. Control óptimo de la concentración de dióxido de carbono en una columna de absorción empacada mediante un modelo de red neuronal artificial

Author: Iván L. Osorio L. and Venancio S. Navarro R.
Subjects: General Earth and Planetary Sciences
Abstract: El objetivo de este trabajo de investigación fue realizar el control óptimo de la composición de dióxido de carbono en la columna de absorción empacada del Laboratorio de Operaciones y Procesos Unitarios de la Facultad de Ingeniería Química mediante un modelo de red neuronal artificial. Un modelo de red neuronal artificial con una capa de entrada, una capa escondida y una capa de salida fue desarrollado, entrenado con el algoritmo de retropropagación y validado experimentalmente para un proceso de absorción con reacción química. Asimismo, siguiendo el mismo procedimiento fue implementado el modelo del neurocontrolador (modelo inverso de la red neuronal artificial). El trabajo experimental fue realizado en una columna de absorción de vidrio pyrex de 1.15 metros de altura y 8.5 centímetros de diámetro interno, empacada con anillos Raschig de vidrio de 20 milímetros y opera con un rango en el flujo de gas de 12 a 16 L/min y un rango en el flujo de líquido de 0.8 a 2.8 L/min. La variable controlada fue la concentración de dióxido de carbono a la salida de la columna de absorción en un rango de 4 a 8 %V y la variable manipulada fue la velocidad de flujo de entrada de la solución de hidróxido de sodio 0.11M en un rango de 0.8 a 2.8 L/min. Para contrastar la hipótesis el neurocontrolador fue probado experimentalmente estableciéndose diferentes valores de referencia (set points) y el control óptimo de la columna de absorción demostró ser realizable suministrando una adecuada acción de control para alcanzar los valores de referencia deseados
Published: 2019

106. Propiedades psicométricas de una escala de autoeficacia académica en una muestra de adolescentes peruanos

Author: Jhonatan S. Navarro-Loli and Sergio Dominguez-Lara
Subjects: Clinical Psychology, Sociology and Political Science, Social Psychology, Education
Abstract: El objetivo de la presente investigación es evaluar las propiedades psicométricas de la Escala de Autoeficacia Percibida Específica de Situaciones Académicas (EAPESA). La muestra estuvo conformada por 308 adolescentes (157 varones) de nivel secundaria de una Institución Educativa Estatal de Lima-Perú entre los 13 y 18 años (Medad = 15.22; DEedad = 1.126). Se realizó un análisis factorial confirmatorio con el programa Mplus y se plantearon dos hipótesis estructurales: el modelo original (M1) y una estructura unidimensional en que no se considera el ítem 9 (M2). Además, las puntuaciones se correlacionaron con una medida de afecto positivo y negativo. Los resultados indican M2 es el modelo más plausible en la muestra de adolescentes, la fiabilidad del constructo y de las puntuaciones está en el rango de lo aceptable, y que las asociaciones encontradas con el afecto positivo y negativo son teóricamente coherentes. Se concluye que el EAPESA es un instrumento que se puede utilizar para fines de investigación y descripción de grupos.
Published: 2019

107. Immediate treatment of acute HIV in a tertiary healthcare center: bridging gaps in communication using smartphones

Author: S. Navarro-Álvarez, Santiago Pérez-Patrigeon, Juan Sierra-Madero, Christian Hernández-León, Luis E. Soto-Ramírez, Brenda Crabtree-Ramírez, Juan J. Calva, Pablo F. Belaunzarán-Zamudio, Antonio Camiro-Zúñiga, M.D.R. Jaramillo-Jante, and Juan L. Mosqueda-Gómez
Subjects: 0301 basic medicine, Acute HIV infection, medicine.medical_specialty, business.industry, Health Policy, Human immunodeficiency virus (HIV), medicine.disease_cause, 030112 virology, Antiretroviral therapy, 03 medical and health sciences, Chronic infection, 0302 clinical medicine, Infectious Diseases, Emergency medicine, Cohort, Epidemiology, Medicine, Pharmacology (medical), 030212 general & internal medicine, business, Survival analysis, Tertiary healthcare
Abstract: Objectives Early initiation of antiretroviral therapy (ART) during acute HIV infection is associated with favourable clinical and epidemiological outcomes. Barriers to prompt treatment initiation limit the benefits of universal access to ART in Mexico. We sought to create an algorithm for the immediate detection and treatment of patients with acute HIV infection. Methods A nationwide cohort of patients with acute HIV infection was created in 2015. In order to identify cases and treat them promptly at our centre, an interdisciplinary group coordinated through an instant-messaging tool using smart phones was established. When a probable case was detected, a discussion was initiated to confirm the diagnosis and facilitate the administrative processes to initiate ART as soon as possible. We compared time to ART initiation with that in a comparison group of patients with chronic HIV infection enrolled during the same period (May 2015 to February 2017) through routine care, using survival analysis estimators and log-rank tests. Results We recruited 29 patients with acute HIV infection. The median time to ART initiation was 2 days in these patients, in contrast to 21 days for patients with chronic infection. There were no significant differences in the percentages of patients engaged in care, on treatment or virologically suppressed at 1 year of follow-up. Conclusions Implementing immediate ART initiation programmes is feasible in Mexico, in spite of the substantial administrative barriers that exist in the country. More extensive replication of this model in other centres and in patients with chronic infection is warranted to evaluate its effect on the continuum of care.
Published: 2019

108. Impact of the baseline study with penile doppler ultrasound in patients with prostate cancer before radical prostatectomy

Author: A. Domínguez, N. Hannaoui, M.A. Rosado, V. Parejo, S. Navarro, J. Muñoz-Rodríguez, J. Prats, and C. Centeno
Subjects: Baseline study, medicine.medical_specialty, High prevalence, Prostatectomy, business.industry, medicine.medical_treatment, 030232 urology & nephrology, Urology, Charlson index, General Medicine, medicine.disease, 03 medical and health sciences, Prostate cancer, 0302 clinical medicine, Erectile dysfunction, medicine, In patient, Doppler ultrasound, business
Abstract: Introduction Given the high prevalence of erectile dysfunction in male population between 40 and 70 years old and the effect of radical prostatectomy on this domain, it is important to perform a baseline study. Material and methods Prior radical prostatectomy, erectile function has been assessed prospectively in 112 prostate cancer patients using the erectile function (EF) domain of the International Index of Erectile Function (EF-IIEF), Erectile Hardness Score (EHS) and a penile doppler ultrasound (PDUS). Comorbidities and Charlson index were collected. The EORTC QLQ C-30 and PR-25 tests were administered. Results According to EF-IIEF questionnaire, 50.9% of patients showed normal EF and EHS grade 3–4 erection was achieved in the 75.9%. PDUS was normal only in 28.6% of patients and 51.8% showed arterial insufficiency. We found a significant association (p Conclusions In order to predict EF recovery after surgery, global assessment is required. Solely self-administered tests are not enough. In this baseline study, PDUS can play an important role.
Published: 2019

109. Impacto del estudio basal con ecografía doppler en pacientes con cáncer de próstata previo a prostatectomía radical

Author: N. Hannaoui, J. Prats, M.A. Rosado, V. Parejo, C. Centeno, S. Navarro, A. Domínguez, and J. Muñoz-Rodríguez
Subjects: Gynecology, 03 medical and health sciences, medicine.medical_specialty, 0302 clinical medicine, business.industry, Urology, 030232 urology & nephrology, Medicine, business, Ultrasonography doppler
Abstract: Resumen Introduccion La disfuncion erectil peneana tiene una prevalencia alta entre los 40-70 anos, por lo que es importante su valoracion basal antes de la prostatectomia radical. Material y metodos Se ha evaluado la funcion erectil (FE) de 112 pacientes con cancer de prostata previamente a la prostatectomia radical, mediante el dominio de la FE del Indice Internacional de Funcion Erectil (IIEF), el test Erectile Hardness Score (EHS) y una ecografia doppler de pene (EDP). Se recogieron comorbilidades, el indice de Charlson y se administro el test de calidad de vida de la EORTC QLQ C -30 y PR-25. Resultados Un 50,9% de la poblacion tenian una FE normal usando el cuestionario IIEF y un 75,9% conseguian una ereccion grado 3-4 en el EHS. Unicamente el 28,6% presentaban una EDP normal, y el 51,8% mostraron insuficiencia arterial. Encontramos una asociacion significativa (p Conclusiones Es importante una valoracion global de la FE para poder valorar las expectativas de recuperacion de dicha funcion tras la cirugia y no reducirla unicamente a test autoadministrados, pudiendo jugar un papel importante la EDP.
Published: 2019

110. Preventing the recurrence of depression with a Mediterranean diet supplemented with extra-virgin olive oil. The PREDI-DEP trial: study protocol

Author: R. Vega-Pérez, P. Vega-Pérez, M. Florido-Rodríguez, M. J. Calviño-Cabada, B. Cabrera-Suárez, Felipe Ortuño, J. L. Hernández-Fleta, S. Navarro, Y. Almeida, Almudena Sánchez-Villegas, J. Pla, Francisca Lahortiga-Ramos, Ana González-Pinto, C. Chiclana-Actis, Patricio Molero, and C. Cabrera
Subjects: Male, medicine.medical_specialty, Dieticians, Mediterranean diet, lcsh:RC435-571, Extra-virgin olive oil, Diet, Mediterranean, law.invention, 03 medical and health sciences, Study Protocol, 0302 clinical medicine, Quality of life, Randomized controlled trial, law, Internal medicine, lcsh:Psychiatry, Epidemiology, medicine, Secondary Prevention, Humans, 030212 general & internal medicine, Exercise, Olive Oil, Depression (differential diagnoses), Randomized Controlled Trials as Topic, Depressive Disorder, business.industry, Depression, Beck Depression Inventory, Middle Aged, 030227 psychiatry, Clinical trial, Psychiatry and Mental health, Dietary Supplements, Quality of Life, Recurrence of depression, Female, business
Abstract: Background The role of dietary patterns in the prevention of unipolar depression has been analyzed in several epidemiological studies. The primary aims of this study are to determine the effectiveness of an extra-olive oil-enriched Mediterranean diet in reducing the recurrence of depression and improving the symptoms of this condition. Methods Multicenter, two-arm, parallel-group clinical trial. Arm 1, extra-virgin olive oil Mediterranean diet; Arm 2, control group without nutritional intervention. Dieticians are in charge of the nutritional intervention and regular contact with the participants. Contacts are made through our web platform (https://predidep.es/participantes/) or by phone. Recurrence of depression is assessed by psychiatrists and clinical psychologists through clinical evaluations (semi-structured clinical interviews: Spanish SCID-I). Depressive symptoms are assessed with the Beck Depression Inventory. Information on quality of life, level of physical activity, dietary habits, and blood, urine and stool samples are collected after the subject has agreed to participate in the study and once a year. Discussion To the best of our knowledge, the PREDI-DEP trial is the first ongoing randomized clinical trial designed to assess the role of the Mediterranean diet in the prevention of recurrent depression. It could be a cost-effective approach to avoid recurrence and improve the quality of life of these patients. Trial registration The study has been prospectively registered in the U.S. National Library of Medicine (https://clinicaltrials.gov) with NCT number: NCT03081065. Electronic supplementary material The online version of this article (10.1186/s12888-019-2036-4) contains supplementary material, which is available to authorized users.
Published: 2019

111. Tuning Polymer Hydrophilicity to Regulate Gel Mechanics and Encapsulated Cell Morphology

Author: Renato S. Navarro, Michelle S. Huang, Julien G. Roth, Kelsea M. Hubka, Chris M. Long, Annika Enejder, and Sarah C. Heilshorn
Subjects: Biomaterials, Azides, Polymers, Biomedical Engineering, Endothelial Cells, Humans, Pharmaceutical Science, Hydrogels, Hyaluronic Acid, Hydrophobic and Hydrophilic Interactions, Article
Abstract: Mechanically tunable hydrogels are attractive platforms for 3D cell culture, as hydrogel stiffness plays an important role in cell behavior. Traditionally, hydrogel stiffness has been controlled through altering either the polymer concentration or the stoichiometry between crosslinker reactive groups. Here, an alternative strategy based upon tuning the hydrophilicity of an elastin-like protein (ELP) is presented. ELPs undergo a phase transition that leads to protein aggregation at increasing temperatures. It is hypothesized that increasing this transition temperature through bioconjugation with azide-containing molecules of increasing hydrophilicity will allow direct control of the resulting gel stiffness by making the crosslinking groups more accessible. These azide-modified ELPs are crosslinked into hydrogels with bicyclononyne-modified hyaluronic acid (HA-BCN) using bioorthogonal, click chemistry, resulting in hydrogels with tunable storage moduli (100-1000 Pa). Human mesenchymal stromal cells (hMSCs), human umbilical vein endothelial cells (HUVECs), and human neural progenitor cells (hNPCs) are all observed to alter their cell morphology when encapsulated within hydrogels of varying stiffness. Taken together, the use of protein hydrophilicity as a lever to tune hydrogel mechanical properties is demonstrated. These hydrogels have tunable moduli over a stiffness range relevant to soft tissues, support the viability of encapsulated cells, and modify cell spreading as a consequence of gel stiffness.
Published: 2022

112. Secondary disseminated intraperitoneal hydatid cyst: A case report

Author: Siegfredo R, Paloyo, Derick V, Cabahug, Earl Nathaniel P, Cruz, Bernice C, Navarro, and Narciso S, Navarro
Subjects: Surgery
Abstract: Hydatidosis is an uncommon zoonotic infection in the Philippines with only a few reported cases. It frequently presents as benign liver cysts with variable symptoms often related to mass effect.We present a 49-year-old male with a significant travel history from East and Central Asia, surgically treated twice as a benign liver cyst and now presenting with recurrent multiple intraabdominal cysts. He subsequently underwent surgical excision of multiple hydatid cysts with prolonged albendazole treatment. The patient presently remains disease-free as of most recent follow-up.The disease is caused by the tapeworm Echinococcus granulosus and transmission happens when humans acting as intermediate host ingest food contaminated with the parasite eggs, resulting to the liver being the most common location. Frequently, it manifests and is treated as incidental hepatic cysts for the disease is characterized to have a long asymptomatic period. Symptoms are variable and may range from having abdominal pain, increasing abdominal girth, vomiting, fever or myalgia. Ultrasound or CT scan reveals single or multiple cysts however, biopsy of the cyst wall with demonstration of the larval form (protoscoleces) is diagnostic.This case highlights the value of history-taking and having a high-index of suspicion particularly for rare cases.
Published: 2022

113. Evaluating the environmental performance of orange production in Veracruz, Mexico: A life cycle assessment approach

Author: Joel Bonales-Revuelta, Ricardo Musule, Freddy S. Navarro-Pineda, and Carlos A. García
Subjects: Renewable Energy, Sustainability and the Environment, Strategy and Management, Building and Construction, Industrial and Manufacturing Engineering, General Environmental Science
Published: 2022

114. Conceptual design of a dedicated‐crop biorefinery for <scp> Jatropha curcas </scp> using a systematic sustainability evaluation

Author: Julio C. Sacramento Rivero, Robert M. Handler, and Freddy S. Navarro-Pineda
Subjects: biology, Renewable Energy, Sustainability and the Environment, 020209 energy, Bioengineering, 02 engineering and technology, Agricultural engineering, 010501 environmental sciences, Biorefinery, biology.organism_classification, 01 natural sciences, Crop, Conceptual design, Biofuel, Sustainability, 0202 electrical engineering, electronic engineering, information engineering, Environmental science, Jatropha curcas, 0105 earth and related environmental sciences
Published: 2018

115. Searching for pulsars in the Galactic Centre at 3 and 2 mm

Author: Miguel Sánchez-Portal, A. Noutsos, Carsten Kramer, Luciano Rezzolla, Karl Schuster, Pablo Torne, Kuo Liu, S. Navarro, R. P. Eatough, S. Sánchez, Heino Falcke, Gregory Desvignes, Michael Kramer, Robert Wharton, Gabriel Paubert, Ramesh Karuppusamy, Instituto de RadioAstronomía Milimétrica (IRAM), Centre National de la Recherche Scientifique (CNRS), Laboratoire d'études spatiales et d'instrumentation en astrophysique (LESIA (UMR_8109)), Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), and Institut de RadioAstronomie Millimétrique (IRAM)
Subjects: Milky Way, Astronomy, Astrophysics::High Energy Astrophysical Phenomena, Population, black hole physics, FOS: Physical sciences, Astrophysics::Cosmology and Extragalactic Astrophysics, 01 natural sciences, stars: magnetars, Pulsar, surveys, pulsars: general, 0103 physical sciences, education, 010303 astronomy & astrophysics, Astrophysics::Galaxy Astrophysics, High Energy Astrophysical Phenomena (astro-ph.HE), Physics, education.field_of_study, Supermassive black hole, Galaxy: center, 010308 nuclear & particles physics, Star formation, scattering, Astronomy and Astrophysics, Galaxy, Black hole, Sagittarius A, Space and Planetary Science, [PHYS.ASTR]Physics [physics]/Astrophysics [astro-ph], Astrophysics - High Energy Astrophysical Phenomena
Abstract: Pulsars in the Galactic centre promise to enable unparalleled tests of gravity theories and black hole physics and to serve as probes of the stellar formation history and evolution and the interstellar medium in the complex central region of the Milky Way. The community has surveyed the innermost region of the galaxy for decades without detecting a population of pulsars, which is puzzling. A strong scattering of the pulsed signals in this particular direction has been argued to be a potential reason for the non-detections. Scattering has a strong inverse dependence on observing frequency, therefore an effective way to alleviate its effect is to use higher frequencies in a survey for pulsars in the Galactic centre, in particular, close to the supermassive black hole Sagittarius A*. We present the first pulsar survey at short millimetre wavelengths, using several frequency bands between 84 and 156 GHz (3.57-1.92 mm), targeted to the Galactic centre. The observations were made with the Institut de Radioastronomie Millimetrique (IRAM) 30m Telescope in 28 epochs between 2016 December and 2018 May. This survey is the first that is essentially unaffected by scattering and therefore unbiased in population coverage, including fast-spinning pulsars that might be out of reach of lower-frequency Galactic centre surveys. We discovered no new pulsars and relate this result mainly to the decreased flux density of pulsars at high frequencies, combined with our current sensitivity. However, we demonstrate that surveys at these extremely high radio frequencies are capable of discovering new pulsars, analyse their sensitivity limits with respect to a simulated Galactic centre pulsar population, and discuss the main challenges and possible improvements for similar surveys in the future., 14 pages, 6 figures, 4 tables. Accepted for publication in A&A. This version includes language editor corrections
Published: 2021

116. Abstract P369: Cerebral Small Vessel Disease and Enlarged Cardiac Ventricles

Author: Adam de Havenon, Eric D. Goldstein, Kayla S. Navarro, Ka-Ho Wong, and Majd Ibrahim
Subjects: Advanced and Specialized Nursing, medicine.medical_specialty, business.industry, Hemodynamics, Cardiac Ventricle, Disease, medicine.disease, Hyperintensity, Internal medicine, cardiovascular system, Cardiology, Medicine, Neurology (clinical), Small vessel, Cardiology and Cardiovascular Medicine, business, Stroke
Abstract: Introduction: White matter hyperintensities (WMH) are a radiographic marker for cerebral small vessel disease (CSVD). Conditions altering cerebral venous outflow such as elevated central venous pressure and right atrial pressure in individuals with cardiac valvular disease have been implicated in the development of WMH. Hypothesis: We hypothesize that increased right-heart chamber size in individuals without significant cardiac valvular disease is associated with worse WMH. Methods: A retrospective chart review of adults with a brain MRI and a 2-dimensional transthoracic echocardiogram (TTE) was performed. Worst burden of WMH by way of Fazekas score, either periventricular or deep white matter, served as the primary outcome. Statistical analysis was performed using a multivariate ordinal logistic regression model. Results: A total of 132 individuals were included. Right atrial area (OR 0.93, 95% CI 0.87 to 1.00, p = 0.0041), right ventricular internal diameter (OR 0.48, 95%CI 0.27 to 0.83, p = 0.008) and left atrial area (OR 0.93, 95%CI 0.88 to 0.98, p = 0.007) was identified as being significant. Cardiac functional markers were not significant, including tricuspid annular plane systolic excursion (OR 0.99, 95%CI 0.93 to 1.05, p = 0.670), right ventricular ejection fraction (OR 0.99, 95%CI 0.96 to 1.02, p = 0.670) and left ventricular ejection fraction (OR 0.99, 95%CI 0.96 to 1.02, p = 0.567). Analysis of isolated DWM or PVWM Fazekas scores did not find significant predictors in relation to cardiac structure or function. Conclusions: Through non-invasive cardiac imaging, we identified that cardiac structural abnormalities as opposed to functional abnormalities were associated with worse WMH. Mechanistically this may result from altered intracerebral arteriovenous coupling or a shared pathophysiologic pathway between WMH and coronary microvascular disease.
Published: 2021

117. The association between transthoracic echocardiogram parameters and white matter hyperintensities

Author: Adam de Havenon, Ka-Ho Wong, Majd Ibrahim, Eric D. Goldstein, and Kayla S. Navarro
Subjects: Male, medicine.medical_specialty, Heart Ventricles, Hemodynamics, Normal values, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, Medicine, Humans, Heart Atria, Stroke, Aged, Retrospective Studies, Ejection fraction, business.industry, Confounding, Brain, General Medicine, Middle Aged, medicine.disease, White Matter, Hyperintensity, Echocardiography, 030220 oncology & carcinogenesis, Cardiac chamber, Cerebral Small Vessel Diseases, cardiovascular system, Cardiology, Surgery, Female, Neurology (clinical), Transthoracic echocardiogram, business, 030217 neurology & neurosurgery
Abstract: Objective Identify abnormal cardiac chamber size and hemodynamic parameters on transthoracic echocardiogram (TTE) as predictors of advancing cerebral small vessel disease (CSVD) on brain magnetic resonance imaging (MRI). Materials and methods A retrospective chart review of adults with a brain MRI and a 2-dimensional TTE was performed. WMH measured by the Fazekas score served as the primary outcome. We fit multivariate ordinal logistic regression models to the Fazekas score with the individual predictors of the TTE measurements and adjusted for potential confounders. Results 132 individuals were included. Cardiac functional markers were not significant, including tricuspid annular plane systolic excursion (p = 0.818), right ventricular ejection fraction (p = 0.818) and left ventricular ejection fraction (p = 0.673). Cardiac structural markers included right atrial area (p = 0.247), right ventricular internal diameter (RVID, p = 0.020) and left atrial area (LAA, p = 0.041). RVID and LAA were identified as being predictors, although the direction of the association suggested that normal values resulted in more WMH. Analysis of isolated DWM or PVWM Fazekas scores were not associated with cardiac structure or function. Conclusions In our study, we found that normal LAA and RVID values were associated with an increased degree of WMH on MRI. This finding may represent earlier identification of WMH prior to TTE cardiac changes. Future studies are needed for more robust quantitative comparison as well as evaluation prospectively of the association between cardiac chamber sizes and development of WMH.
Published: 2021

118. Additional file 2 of Reproductive fluids, used for the in vitro production of pig embryos, result in healthy offspring and avoid aberrant placental expression of PEG3 and LUM

Author: E. París-Oller, S. Navarro-Serna, C. Soriano-Úbeda, J. S. Lopes, C. Matás, S. Ruiz, R. Latorre, O. López-Albors, R. Romar, S. Cánovas, and Coy, P.
Subjects: fluids and secretions, animal diseases
Abstract: Additional file 2: Table S2. Pregnancy and farrowing results after transfer of in vitro produced embryos produced with/without reproductive fluids.
Published: 2021
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119. BJS commission on surgery and perioperative care post-COVID-19

Author: E. Abahuje, A. Abbas, M. Abd El Aziz Abd El Maksoud, A. Abdelhady, S. Abdelhamid, H. Abdelkarem Ahmed Faraj, B. Abdelqader, T. Abdelrahman, H. Abdou, A. Abdullah, M. Abedua Harrison, E. Abem Owusu, A. Aboalazayem, R. Aboulhosn, S. Abu Oda, A. Abubakar, A. Abutaka, D. Acevedo Fontalvo, S. Acuna, A. Adefemi, S. Adegbola, T. Adenuga, A. Adeyeye, A. Adil Hilmi, A. Adisa, K. Aditya, T. Adjeso, R. Aftab, A. Afzal, V. Aggarwal, A. Aggarwal, R. Aguilera, M. -L. Aguilera-Are´valo, E. J. Aguirre Salamanca, I. Aguirre-Allende, D. Ahari, H. Ahmad, F. Ahmad Rauf, A. Ahmad Zartasht Khan, S. Ahmed, N. Ahmed Fieturi, S. Ahmed Mohamed, Z. Ahmed-Bakhsh, M. Ahsan Javed, L. Akano, A. Akbar, M. Akhbari, P. Akhmedov, G. Aksit, Y. Akula, A. S. Alagaratnam, S. Al Majid, O. Al Mukhtar, H. Al Omran, N. AlAsali, M. Al-Azzawi, R. Al-Habsi, H. Al-Iraqi, H. Al-Naggar, E. Alameer, H. Albirnawi, D. Alderson, F. Aldulaijan, R. Alejandro Miranda Ojeda, A. AlHasan, S. Ali, A. Ali, M. Ali Khan, Y. Alimova, F. Aljanadi, R. Aljubure, N. Allopi, H. Almedbal, M. Almubarak, Z. Alqaidoom, N. Alselaim, M. Alshaar, R. Alshammari, K. Altaf, S. Altıner, B. Altunpak, L. A. Alvarez Lozada, E. Amal Nahal, A. Amer, K. Amin, U. Aminu, N. Amisi Numbi, T. Amjad, R. Amoah, Y. An, N. -A. Anastasopoulos, J. Andre´s Urrutia, F. Angarita, K. -L. Angarita, M. A´ ngel FreirI´a Eiras, A. Antypas, M. A. Anwar, H. Anwar, T. O. Apampa, K. Apostolou, C. Aquina, R. Arachchige Adithi Himika Randeni, M. I. Archila Godı´nez, O. Arez, A. A. Arezzo, P. Armonis, S. Arshad, M. Arshad Salman, A. Arshid, P. C. Arteaga Asensio, T. Arthur, A. Arumuga Jothi, F. Aryo Damara, L. Asensio Gomez, J. Ashcroft, S. Ashraf, A. Asif, M. Atif, M. Attaullah Khan, N. Avellaneda, S. Awad, M. Awadh, A. Axiaq, A. Ayad Mohammed Shuwayyah, D. Ayalew, E. Aytac, F. Azam, J. Azevedo, B. Azhar, J. Aziz, A. Aziz, A. Azzam, A. Baba Ndajiwo, M. Baig, D. Baker, F. Bakko, R. Balachandran, G. Balachandran, J. Balagizi Mudekereza, E. Balai, B. Balci, A. Balduzzi, A. Balhareth, S. Bandyopadhyay, D. Banerjee, D. Bangalore Mahalinga, B. Bankhead-Kendall, N. D. A. Bankole, V. Banwell, F. Baris Bengur, B. Baris Ozmen, M. Barnard, R. Barnett, J. A. Barreras Espinoza, A. Barrios, G. Bass, M. Bass, A. Bausys, A. Bavikatte, J. Bayram, M. Belousov, A. G. Berardi, A. Beamish, C. Beattie, F. Belia, V. Bellato, S. Bellikatti, S. Benjamens, C. Benlice, S. Bennedsgaard, S. Bennett, Z. Bentounsi, H. Bergenfeldt, A. Bergenfelz, M. Besselink, G. Bhandoria, E. Bhangu, M. Bhatia, M. T. Bhatti, Z. Bilgili, G. Bislenghi, C. Bisset, S. Biswas, J. Blake, R. Blanco, L. Boccalatte, R. Boden, C. Bojanic, M. Boland, P. Boland, E. Bollen, E. -A. Bonci, L. Boni, A. Booth, R. Booth, A. Borakati, G. E. Borunda Escudero, S. J. Bosco, P. Bostro¨ m, P. Botelho de Alencar Ferreira Cruz, K. Bouchagier, A. Bouhuwaish, M. Boutros, K. Boyce, C. Boyle, L. Bradshaw, A. Brandl, A. Brar, G. Brat, H. Brenkman, C. Brennan, C. Brines, A. Brookmyre, C. Brosnan, L. Brouwers, A. Brown, L. Brown, C. Brown, J. Brown, V. BS, M. Buksh, M. Bunani Emmanuel, D. Burbano, A. Burelli, A. Burke, J. Burke, N. Burlov, A. Burns, O. Burton, A. Butt, B. Buzra Ozkan, L. Cabrera Silva, E. Y. Caicedo, T. Calderbank, W. Cambridge, G. Campelo, O. Can Tatar, F. Carbone, F. Carrano, D. Casallas, D. Casanova Portoles, F. Casciani, I. Cassimjee, O. A. Castaneda Ramı´rez, V. Catala´ n, J. Caviedes, L. Cayetano, M. ~ Ceresoli, M. Chan, V. Chan, P. Chandrasinghe, S. Chapman, A. Chaturvedi, D. Chaudhry, H. Chaudry, H. W. Chen, A. Cheng, M. Chernykh, A. M. Cherrie, I. Cheruiyot, J. Cheung, C. Chia, J. Chica, N. Chinai, A. Chirwa, J. Chiwaligo, A. Choi, J. Choi, M. R. Chowdhury, E. Christopher, N. Christou, T. Chu, D. Chua, H. W. Chua, C. Chung, A. Cihat Yildirim, M. Cillo, S. Cioffi, H. Claireaux, S. Clermonts, R. Clifford, M. Climent, A. Clynch, R. -J. Coelen, E. Cola´ s-Ruiz, A. Collar, M. Collard, K. C. Conlon, T. Connelly, K. Connor, J. A. Cook, T. Correia de Sa´, N. Cos¸gun Acar, T. Costa, D. Couch, S. Cowper, B. Creavin, B. Crook, A. Curell, R. D’alessio, J. Dale, J. Damgaard Eriksen, I. Dario Martin Gonzalez, A. Darwish, M. Das, R. Das, K. Das, R. Dave, S. O. David, T. Davies, C. Davis, S. Davison, V. Davletshina, A. Dawidziuk, A. Dawson, M. de Andres Crespo, H. de Berker, P. de Dieu Ngo, E. Dekker, R. de la Caridad Espinosa Luis, B. de Lacy, N. Demartines, A. de Montserrat Medina Sifuentes, S. De Silva, C. del Rio, V. Delaune, A. Dell, I. Demirbas¸, S. Demirli Atici, M. Deniz Tepe, M. Derebey, G. Desai, M. Desai, S. Devarakonda, N. Deveras, G. Di Franco, M. Di Martino, F. Di Marzo, A´ . Dı´az, G. Diaz del Gobbo, C. DiazCastrillon, L. Dick, K. Dickinson, E. Diego, I. Dimasi, A. Ding, S. Dingemans, L. Dixon, B. Dixon, W. Doherty, D. Dooreemeah, C. Donohue, M. Dornseifer, F. Dossa, W. Dossou, T. Drake, I. Drami, G. Drevin, M. C. du Plessis, N. Dudi-Venkata, R. Dudley, S. Duffy, D. Duklas, B. -D. Dumbrava, F. Duygu Avlar, A. Dworzynska, W. Ebrahim, A. Ebrahim, E. Efre´n Lozada Herna´ ndez, N. Ehigie, M. El Boghdady, C. El Hasnaoui, M. El Sheikh, A. El-Hussuna, O. Eldurssi, H. Elfeki, M. Elhadi, M. Elhassan, A. Elhissi, B. Elliot, C. Elsenbroek, B. Elsolh, N. Elson, H. Eltyeb, H. Emerson, S. H. Emile, G. Endalle, W. English, C. Ercisli, G. Espinosa, M. Essam Abdelraheem, H. Essangri, P. Etienne, M. D. Evans, T. Evans, C. Ezeme, F. Ezzahraa, T. Fadalla, J. Fagan, M. Fahmy, C. Fairfield, O. Falade, S. Famularo, F. Faqar-Uz-Zaman, Y. Farid, A. Farooq, H. Farooq, F. Farooqui, B. Farquharson, A. Faruqi, R. Faulder, M. Faut, K. Fechner, T. Feenstra, M. Fehervari, L. Fernandez, J. Ferna´ ndez Alberti, L. Ferrario, D. Field, L. Fiore, S. Fingerhut, S. Finlayson, N. Fleming, C. Fleming, E. Florial, M. Fok, D. Fokin, M. Foley, M. P. Forero, T. Forgan, M. Fornasiero, H. Fowler, G. Fowler, E. Franchi, L. Franklin, A˚ . Fredriksson, P. Fruhling, G. Fuentes Navarrette, A. Fu¨ lo¨ p, M. Furtado, T. Gaarder, N. Galbraith, I. T. K. Gallagher, G. Gallo, T. Gana, E. Gaskin, M. Gasparini, R. G. Gatan, E. Geary, K. Gelaye Wudineh, G. Gemenetzis, M. Georgi, H. Ghalige, W. Ghareeb, T. Ghatwary Tantawy, C. Ghomsi, A. Ghuman, P. Giannakis, F. Giron, K. Gjengedal, E. Gkotsis, J. Glasbey, S. Godahewa, D. Godula, P. Goffredo, S. Goh, M. Golriz, L. Gomez, D. Gomez Gomez, R. Gonzalez, D. Gonzalez, E. Gonzalez Gutierrez, D. Gopar, L. Gordini, A. Gori, S. Gorta´ zar, N. Gousy, R. Gowda, M. Gowda, J. Gqada, M. Grechenig, J. Greer, L. Grego´ rio, A. Grigorova, H. Grimes, V. Groot, R. C. Grossman, R. Gruber, A. Gru¨ ter, R. Guest, R. Gujjuri, E. Gu¨ lc¸ek, B. Gulcu, K. Gull, M. Gulmez, V. Gupta, A. Gutlic, T. Guven, T. Gwatirisa, G. Gwini, P. Gwodog, S. Gysling, M. Habib, A. B. Hafeez Bhatti, J. Hallesmith, S. Halloran, M. Hamza Sadiq, C. Haney, N. Hanna, L. Hanna, M. Hannington, J. Harbjerg, D. Haribaskaran, N. Harran, B. Harrington, E. Harrison, R. Hasan, S. Hashmi, M. Hassan, A. Hassan, L. Haverkamp, S. Hazen, B. Heer, J. Heil, J. Helliwell, N. Henriksen, D. Henshall, M. Hermanson, S. Hermena, D. Hettiarachchi, C. Hextall, M. Hidalgo, H. Hidayat, A. Hider, P. Higgins, R. Hinchliffe, D. Hirani, D. Hirpara, I. Hisham, M. Hite, S. M. Hoh, C. Holmberg, E. Ho¨ lmich, F. Holst, A. Hossam, A. Hossam Elfallal, P. Howard, E. Huaman, Y. Huang, L. Huang, D. Huang, T. Huber, J. Hugh, J. Hughes, F. Hu¨ ttner, R. Huynh, A. Hylands, J. Iannuzzi, B. Ielpo, A. Iftikhar Talib, J. Ignacio, P. Ignatavicius, S. Ike, C. Ikwu, M. Inama, A. Ing, A. Ingels, A. Isik, N. Islam, I. J. Ives, A. J. M. S. AlHasan, C. J. Perez Rivera, F. Ja´ come, T. Jaffer, O. Jagiella-Lodise, M. Jain, K. Jain, M. Jakubauskas, M. Jalal, H. James, Y. Jang, B. Janssen, H. Jansson, U´ . Jariod-Ferrer, H. Javanmard, S. Javed, U. Jayarajah, I. Jayasuriya, J. Je, Z. Jessop, E. Jia Lin Tang, H. Jiang, Y. Jiayan, T. Jih Huei, R. Jimenez-Rodriguez, D. Joh, A. Johnson, N. Jones, C. Jones, C. Jordan, J. Jose´ Nu´ nez Ju, ~ M. Jose´ Pizarro, C. Jose Salazar J. Joseph, C. Justiniano, T. Kabir, M. Kadhum, C. Kalfountzos, E. Kalogiannaki, K. Kalyanasundaram, S. Kamarajah, M. Kamil Quraishi, Y. Kanemitsu, A. Kapila, V. Kapila, G. Karagiannidis, M. Kashif, S. Kathiravelupillai, A. Kathiravelupillai, E. Katsogridakis, K. Kaur, H. Kaur Sekhon Inderjit Singh, N. Kausur, M. Kawka, G. Keehan, S. Kehlet Watt, M. Kelly, M. E. Kelly, I. Kelvin Egbuchulem, G. Kembuan, E. Khajeh, A. Khaled Elfaitur, M. F. Khan, S. Khan, M. Khan, D. Khan, H. Khan, H. Khatkar, E. Khatkov, R. Khaw, B. Kim, K. Kishore Siddiraju, D. Kitua, B. Kırımtay, S. Kmezic, S. Knight, T. Koe¨ter, A. Koh, F. Koh Hong Xiang, T. Kojo Anyomih, A. I. N. Kok, R. Kokelaar, I. Koliarakis, S. Kolli, J. Kong, D. Ko¨ nig, M. otze, A. Kourdouli, M. Kowal, A. Kraima, F. Kramer, M. Kryzauskas, I. Kuchynskyi, C. Kuemmerli, S. Kuiper, S. Kumar, A. Kumar, L. Kumar, H. Kumar, N. Kumar, S. Kumar Bandyopadhyay, P. Kumar Garg, S. Kumar Venkatappa, J. Kung, S. Kural, A. Kushairi, E. Kuuzie, M. Kvietkauskas, I. Kwek, J. La, L. Lai, S. Lakpriya, K. Lam, M. Lami, I. Lansdorp-Vogelaar, P. Lapolla, H. Larsen, J. Latif, U. Laudari, A. Laurnezi, A. Lawal, S. Lawday, H. Lederhuber, A. Lednev, R. Lee, M. E. van Leerdam, G. Lefevbre, M. Lesmus, F. A. Leyva Moraga, E. Leyva Moraga, F. Leyva Moraga, H. L. Li, A. Li, Z. Li, E. Licardie, A. Light, A. L. Lightner, A. Lin, E. Lincango, F. Litta, H. Liu, B. Lofthouse, M. A. Londono, R. Lopes, R. Lopes de Freitas, L. Lopez, A. I. Lo´ pez, J. ~ Lopez-Gomez, G. Lopez-Pena, R. Lowe, D. Lowe, M. Lowey, G. Loy, V. Lozanovski, J. Luzon, P. Lynn, T. Maccabe, A. Machielsen, C. A. Mafla Herrerı´a, L. Maggino, K. Mahawar, D. Mahmood, M. Mahmoud, K. Mahtani, I. Maitra, S. Maji, I. Majiet, L. Mal, J. Malherbe, K. Malhotra, P. Malkomes, E. Man, A. Manan Sheikh, S. Manjunath, R. Manzano Nunez, S. Manzoor, R. Maqsood, G. ~ Marchegiani, F. Marchegiani, D. Marı´n, A. Marin, I. Marks, E. Marson, A. Martensen, D. Martin, G. Martı´n Martı´n, B. Martin-Perez, P. Martinez, P. Marwaha, C. Mashauri, H. Mashbari, Ł. Masior, R. Masri, L. Masud, S. Masudi, G. Mateu Calabuig, S. Math, A. Matrachisia, J. Mayol, D. Mazingi, A. Mazzotta, J. McAlinden, G. McCabe, L. McColm, H. McElvaney, K. McGivern, J. McGovern, E. McGuinness, N. McInerney, S. Mckay, C. McKee, M. McKenna, N. McKenna, K. McLean, S. Mediratta, Y. Medkova, O. Medzhidov, A. Mehraj, M. Mekhael, O. Mekinde, C. Mellenthin, A. Melucci, K. Mentor, J. Merchant, H. Messias, M. Messeha, C. Meza, P. Mhango, M. Miladinov, M. Milagros Niquen Jimenez, P. Miller, E. Mills, A. Milton, O. A. Minayeva, Z. MinHua Zheng, H. Mischlinger, B. Mo¨ ckli, R. Modi, H. M. Mohamed, M. Mohamed, T. Mohamed Abulghasm, S. A. Mohammad, T. O. Mohammed, A. Mohammed, H. Mohan, M. Mohan, I. Moin, V. Mok, G. Molina, J. Moloney, J. Moneim, M. Monfort Mira, B. Montcusı´ Ventura, M. Montouri, M. Moossdorff, I. Mora-Guzma´ n, B. Moran, R. A. R. Mora´ n, S. Moreno-Ordaz, A´ . Morera, R. Morgan, R. Morley, D. Moro-Valdezate, S. Moros, J. -L. Moss, A. Morven, D. Morton, A. Moynihan, M. Moyo´ n, N. Muduli, N. Mugla, W. Mugla, P. Mu¨ ller, G. Mun, R. Mundhada, I. Munir, F. Munoz, E. Mu ~ noz, A. Mu ~ noz, D. ~ C. Munoz Balderas, E. Murgitroyd, V. Murray, S. Murthy, W. ~ Mushiwokufa, H. Mustafa, B. Mustakimov, P. Mutambanengwe, P. Myint, S. Nadkarni, P. A. Naess, S. Nahar, P. Naidoo, R. Nam, S. Nandhra, N. Nanjappa, V. Narasimhan, W. Nardi, M. Nasir, A. Naughton, D. Naumann, S. Navarro, M. Nawaaz Karimbocus, A. Nazir, S. Ndereya, A. Ndong, I. Negoi, D. Nel, D. Nelson, S. Nepal, T. Nugent, D. Nepogodiev, J. Neufeld, J. Ng, D. Ng, C. E. Ng, S. Ngaserin, L. Ngu, E. Ngwenya, R. N. Fhearaigh, T. -K. Nikolousakis, M. Ninkovic, G. Nita, C. Nitschke, E. Noren, T. Noton, A. Novikova, Z. Nowinka, T. Nyakunengwa, A. Nyalundja, I. Nzenwa, H. Ø Kristensen, C. O’Brien, L. O’Brien, S. O’Brien, J. O’Reilly, S. O’Rourke, M. O’Sullivan, M. O’Dwyer, L. Ochieng, E. Oderoha, K. E. Oh, L. O¨ hlberger, M. O¨ lc¸u¨ m, A. Olkina, M. Omkumar, B. Omnitel, D. Oncel Yakar, K. Ong, L. Ong Wei Lin, R. Ooi, S. Ooi, A. Oomman, D. Oon Tyjet, S. Opiyo, J. J. Oscullo Yepez, N. Osei-kuffour, T. Osunronbi, A. Ottlaka´ n, S. Oussama Kacimi, S. Ovaere, A. Ozair, F. Pachler, S. Pai Oo, S. Paiella, L. Panaiotti, N. Panda, S. Pandarinath, D. Pandey, S. Pandrowala, F. Papa Mamadou, M. Paranathala, J. Park, C. Parmar, A. Parvez, L. Pasovic, A. Pasquer, N. Pasumarthy, F. Pata, T. Patel, P. Patel, N. Patel, M. Patel, N. Patron Uriburu, R. Patrone, A. Paul, O. M. Pavan Kumar, A. Pavithran, M. Pedraza Ciro, G. Pellino, A. Peloso, M. T. Pena~ Gallardo, A. Pena Velazquez, J. Perea, L. E. Pe´rez-Sa´ nchez, T. ~ Perra, G. Perrotta, P. Petersson, G. Petra, N. Petrucciani, C. Pickin, V. Pino, E. Pinotti, F. Pinto, P. Plum, F. Podesta, T. Pollini, M. Pompeu Sa´, F. Ponce Leon, H. S. Ponniah, X. Ponte de Sousa, J. Ponton, A. Pontula, M. Popa, A. L. Portilla, F. Posner, S. Post, A. Potolicchio, S. Pouwels, A. Povo, P. Prasad, S. Preciado, R. Preece, D. Proud, J. A. Pulido Segura, N. Puliyath, M. Qui, A. S. Quimbaya Rodrı´guez, W. Raby-Smith, A. Racovit¸a, A. Rad, R. Radwan, M. Rafaih Iqbal, A. Rafik, B. Raguan, M. Rahi, J. -L. Rahiri, J. Rahme, L. Rai, A. Raj, A. Raj Saksena, M. Raja, J. Ramirez, J. Ramzi, J. Ranstam, C. Rao, A. Rashid, B. Ratnayake, K. Rattanasirivilai, K. Raubenheimer, N. Ravikumar, S. Ravn, N. Razoz, W. Rea, A. Regan, M. Rela, A. Remme, C. E. Rey Chaves, A. Reyes, A. Riad, D. Rice, K. Rios Quintana, A. Ritter, M. Roalsø, D. Robinson, J. Rodriguez, F. Rodrı´guez, M. C. Rodriguez, A. Rogers, J. Rohila, D. Romanyuc, I. Romic, M. Rommaneh, G. Rompianesi, F. Rosa, F. Roscio, A. Rose, T. Rotimi, H. Ruiz, J. Ruiz Yucuma, E. Ruiz-U´ car, M. Ruslan, M. Rutega˚ rd, E. Ryan Harper, A. Ryckx, D. Rydbeck, E. Fonseca, A. Sanchez Teran, S. Sanchez Ussa, O. Sandli, H. Sanfey, J. Sanghera, I. Sani, M. Santafe Guerrero, M. Sante Fornasiero, O. Santes Jasso, I. Santos Pereira, H. Santos Sousa, A. Saratzis, A. Sarmiento Alarcon, T. Saumtally, R. Sayyed, M. Schettino, L. Schleimer, T. Schmidt, K. Schondffelt, M. Schwab, A. Scott, H. Searle, L. Sebopelo, B. Seeglier, R. Seishima, D. Semenvov, A. Senent-Boza, J. Sepulveda, M. Serenari, M. Serrano Navidad, I. Sert, E. Sewart, A. Sgro`, V. Shadrina, K. Shah, F. Shahid, M. Shalaby, B. Shankar, J. Shapiro, L. Sharma, A. Sheel, A. Shenfine, S. Shenoy, A. Sherif, N. Shetty, R. Shetty, T. C. Sia, D. Sichimba, H. Siddique, I. Siddiqui, G. Simkens, J. Simoe, H. Simon, L. Sinan, T. Singh, K. Singh, Y. Singh, L. Sinha, L. Siragusa, T. Sluckin, Y. W. Smart, H. Smith, K. Smith, L. Smits, C. Sneep-van Kessel, C. Sohrabi, O. Solo´ rzano Pineda, A. Soma, L. Sooriyapiragasam, K. Søreide, M. Sparavigna, R. Spence, N. Spencer, H. Spiers, A. Spinelli, J. Sprakel, S. Sravanam, M. Srinivasan, R. Srinivasan, A. Staniszewska, S. J. Stanworth, K. Stasinos, R. J. C. Steele, I. Steinholt, M. Steinruecke, B. -J. Stephen, J. Stijns, M. Still, W. Stupalkowska, S. Subba, V. V. Subbotin, P. Sucharitkul, A. Sudarsanam, D. Sudhamsh Reddy, T. Suhardja, M. Suliman, M. Sund, A. Sunilkumar, N. Suresh, S. Sussmes, P. Sutton, J. Syltern, A. Taha, Y. Takamizawa, A. B. Takoutsing Dongmo, T. Tama´ s, L. Tan, J. L. Tan, K. Tan, E. Tan, A. Tan Yong Hui, A. Tanase, A. Tariverdiev, A. Tasnem, C. Tatar, E. Tay, P. Tejedor, G. Tesfaye, F. Tetinou, C. Thorpe, A. Thyø, D. Tlelo Amastal, M. Tolani, K. Tolga Saracoglu, T. To¨ lgyes, J. Tong, L. Torrent Jansa`, S. Toscano Igartua, M. R. Tovani Palone, H. Traff, J. Trevis, W. Tummers, A. Tur, I. Turchenko, V. Uche, A. Uddin, N. Udonsak, M. Ullah, T. Urbonas, C. Uwins, E. Uy Magadia, A. Uzair Qureshi, K. Uzun, P. Vadim, G. Valarche, R. A. Valdez Gonzalez, M. Vallee, D. -J. van Beek, A. S. van Dalen, D. van den Hondel, E. van der stok, M. van Dorp, S. van Oostendorp, E. van Praag, J. van Rees, L. van Silfhout, Z. Varga, S. Varghese, C. Varghese, J. Varghese, A. -M. Vasilica, X. Va´ squez Ojeda, E. Vega, S. Vehler, R. Venchiarutti, S. Vengatesan, M. Venn, D. Verma, G. Vianey Partida Nava, D. Victoria, P. Vieira, M. E. Vilar Alvarez, D. Vinci, G. Viscasillas Palla` s, M. Viswanath, J. Vivanco, V. Vizcaya Rodrı´guez, J. Vo, D. Volchanski, T. Voron, Y. Voronovskyi, J. Vu, M. Wadhwa, S. Wadhwa, G. Wagner, M. Wallace, Y. Y. Wang, J. Wang, A. Wani, K. Wanigasooriya, S. Wanjara, N. Wanjiku, C. Warner, T. Wei Leow, T. Weiser, M. Weisters, M. J. Wellington, C. Wells, C. Wenzelberg, D. Wettstein, A. Wezel, L. Wheldon, L. Widmer, M. Wilson, S. Wigmore, T. Wijayaratne, M. Wijeyaratne, B. P. L. 1176 | BJS, 2021, Vol. 108, No. 10 Sá-Marta, I. Sadien, D. SafariNteranya, K. Sagoo, S. Sakata, E. Saladino, A. Saleem, S. Saleem, M. Salehi, S. Salih, V. Sallinen, S. Salvans, Z. H. Sam, E. Samadov, M. Sampaio Alves, A. Sanad, S. Sánchez Wijnhoven, R. Wilkin, E. Williams, F. Willis, D. Winter, M. M. Wirsik, B. Wishah, G. Wong, W. J. Wong, K. Wong, K. -Y. Wong, D. Worku, E. Wright, J. Wright, O. Wroe Wright, S. Xenacki, W. Xia, W. Xu, Z. Xu, A. Yalcinkaya, W. Yang, P. -C. Yang, A. Yanishev, A. Yanzon de la Torre, H. Yao, E. Yaqoob, S. Yen Ling Quake, D. Yeo, B. Yeom, D. Yershov, M. Yiasemidou, A. Yildiz, A. Yiu, M. Yoav, E. Yong, R. Yoshimura, M. U. Younis, Z. Younis Ringshawl, M. Youssef, Y. Yue, S. Yuen, R. Yuldashev, C. Yurttas, B. Yves, A. Zaborowski, R. Zackeri, A. Zafar, W. Zahra, A. Zaidi, S. Zainudin, R. Zakeri, I. Zamora, A. T. Zamora, M. Zawistowski, G. Zbikowska, W. Zegers, S. Zehra, A. Zeyra, Z. Zhagniyev, L. G. Zhukova, M. Zivanovic, J. Zmuc, M. Zope, A. Zubayraeva, B. Zucker., Abahuje, E., Abbas, A., Abd El Aziz Abd El Maksoud, M., Abdelhady, A., Abdelhamid, S., Abdelkarem Ahmed Faraj, H., Abdelqader, B., Abdelrahman, T., Abdou, H., Abdullah, A., Abedua Harrison, M., Abem Owusu, E., Aboalazayem, A., Aboulhosn, R., Abu Oda, S., Abubakar, A., Abutaka, A., Acevedo Fontalvo, D., Acuna, S., Adefemi, A., Adegbola, S., Adenuga, T., Adeyeye, A., Adil Hilmi, A., K. Aditya, A. Adisa, Adjeso, T., Aftab, R., Afzal, A., Aggarwal, V., Aggarwal, A., Aguilera, R., Aguilera-Are´valo, M. -L., Aguirre Salamanca, E. J., Aguirre-Allende, I., Ahari, D., Ahmad, H., Ahmad Rauf, F., Ahmad Zartasht Khan, A., Ahmed, S., Ahmed Fieturi, N., Ahmed Mohamed, S., Ahmed-Bakhsh, Z., Ahsan Javed, M., Akano, L., Akbar, A., Akhbari, M., Akhmedov, P., Aksit, G., Akula, Y., Alagaratnam, A. S., Al Majid, S., Al Mukhtar, O., Al Omran, H., Alasali, N., Al-Azzawi, M., Al-Habsi, R., Al-Iraqi, H., Al-Naggar, H., Alameer, E., Albirnawi, H., Alderson, D., Aldulaijan, F., Alejandro Miranda Ojeda, R., Alhasan, A., Ali, S., Ali, A., Ali Khan, M., Alimova, Y., Aljanadi, F., Aljubure, R., Allopi, N., Almedbal, H., Almubarak, M., Alqaidoom, Z., Alselaim, N., Alshaar, M., Alshammari, R., Altaf, K., Altıner, S., Altunpak, B., Alvarez Lozada, L. A., Amal Nahal, E., Amer, A., Amin, K., Aminu, U., Amisi Numbi, N., Amjad, T., Amoah, R., An, Y., Anastasopoulos, N. -A., Andre´s Urrutia, J., Angarita, F., Angarita, K. -L., A´ ngel FreirI´a Eiras, M., Antypas, A., Anwar, M. A., Anwar, H., Apampa, T. O., Apostolou, K., Aquina, C., Arachchige Adithi Himika Randeni, R., Archila Godı´nez, M. I., Arez, O., Arezzo, A. A., Armonis, P., Arshad, S., Arshad Salman, M., Arshid, A., Arteaga Asensio, P. C., Arthur, T., Arumuga Jothi, A., Aryo Damara, F., Asensio Gomez, L., Ashcroft, J., Ashraf, S., Asif, A., Atif, M., Attaullah Khan, M., Avellaneda, N., Awad, S., Awadh, M., Axiaq, A., Ayad Mohammed Shuwayyah, A., Ayalew, D., Aytac, E., Azam, F., Azevedo, J., Azhar, B., Aziz, J., Aziz, A., Azzam, A., Baba Ndajiwo, A., Baig, M., Baker, D., Bakko, F., Balachandran, R., Balachandran, G., Balagizi Mudekereza, J., Balai, E., Balci, B., Balduzzi, A., Balhareth, A., Bandyopadhyay, S., Banerjee, D., Bangalore Mahalinga, D., Bankhead-Kendall, B., Bankole, N. D. A., Banwell, V., Baris Bengur, F., Baris Ozmen, B., Barnard, M., Barnett, R., Barreras Espinoza, J. A., Barrios, A., Bass, G., Bass, M., Bausys, A., Bavikatte, A., Bayram, J., Belousov, M., Berardi, A. G., Beamish, A., Beattie, C., Belia, F., Bellato, V., Bellikatti, S., Benjamens, S., Benlice, C., Bennedsgaard, S., Bennett, S., Bentounsi, Z., Bergenfeldt, H., Bergenfelz, A., Besselink, M., Bhandoria, G., Bhangu, E., Bhatia, M., Bhatti, M. T., Bilgili, Z., Bislenghi, G., Bisset, C., Biswas, S., Blake, J., Blanco, R., Boccalatte, L., Boden, R., Bojanic, C., Boland, M., Boland, P., Bollen, E., Bonci, E. -A., Boni, L., Booth, A., Booth, R., Borakati, A., Borunda Escudero, G. E., Bosco, S. J., Bostro¨ m, P., Botelho de Alencar Ferreira Cruz, P., Bouchagier, K., Bouhuwaish, A., Boutros, M., Boyce, K., Boyle, C., Bradshaw, L., Brandl, A., Brar, A., Brat, G., Brenkman, H., Brennan, C., Brines, C., Brookmyre, A., Brosnan, C., Brouwers, L., Brown, A., Brown, L., Brown, C., Brown, J., Bs, V., Buksh, M., Bunani Emmanuel, M., Burbano, D., Burelli, A., Burke, A., Burke, J., Burlov, N., Burns, A., Burton, O., Butt, A., Buzra Ozkan, B., Cabrera Silva, L., Caicedo, E. Y., Calderbank, T., Cambridge, W., Campelo, G., Can Tatar, O., Carbone, F., Carrano, F., Casallas, D., Casanova Portoles, D., Casciani, F., Cassimjee, I., Castaneda Ramı´rez, O. A., Catala´ n, V., Caviedes, J., Cayetano, L., ~ Ceresoli, M., Chan, M., Chan, V., Chandrasinghe, P., Chapman, S., Chaturvedi, A., Chaudhry, D., Chaudry, H., Chen, H. W., Cheng, A., Chernykh, M., Cherrie, A. M., Cheruiyot, I., Cheung, J., Chia, C., Chica, J., Chinai, N., Chirwa, A., Chiwaligo, J., Choi, A., Choi, J., Chowdhury, M. R., Christopher, E., Christou, N., Chu, T., Chua, D., Chua, H. W., Chung, C., Cihat Yildirim, A., Cillo, M., Cioffi, S., Claireaux, H., Clermonts, S., Clifford, R., Climent, M., Clynch, A., Coelen, R. -J., Cola´ s-Ruiz, E., Collar, A., Collard, M., Conlon, K. C., Connelly, T., Connor, K., Cook, J. A., Correia de Sa´, T., Cos¸gun Acar, N., Costa, T., Couch, D., Cowper, S., Creavin, B., Crook, B., Curell, A., D’Alessio, R., Dale, J., Damgaard Eriksen, J., Dario Martin Gonzalez, I., Darwish, A., Das, M., Das, R., Das, K., Dave, R., David, S. O., Davies, T., Davis, C., Davison, S., Davletshina, V., Dawidziuk, A., Dawson, A., de Andres Crespo, M., de Berker, H., de Dieu Ngo, P., Dekker, E., de la Caridad Espinosa Luis, R., de Lacy, B., Demartines, N., de Montserrat Medina Sifuentes, A., De Silva, S., del Rio, C., Delaune, V., Dell, A., Demirbas¸, I., Demirli Atici, S., Deniz Tepe, M., Derebey, M., Desai, G., Desai, M., Devarakonda, S., Deveras, N., Di Franco, G., Di Martino, M., Di Marzo, F., Dı´az, A´., Diaz del Gobbo, G., Diazcastrillon, C., Dick, L., Dickinson, K., Diego, E., Dimasi, I., Ding, A., Dingemans, S., Dixon, L., Dixon, B., Doherty, W., Dooreemeah, D., Donohue, C., Dornseifer, M., Dossa, F., Dossou, W., Drake, T., Drami, I., Drevin, G., du Plessis, M. C., Dudi-Venkata, N., Dudley, R., Duffy, S., Duklas, D., Dumbrava, B. -D., Duygu Avlar, F., Dworzynska, A., Ebrahim, W., Ebrahim, A., Efre´n Lozada Herna´ ndez, E., Ehigie, N., El Boghdady, M., El Hasnaoui, C., El Sheikh, M., El-Hussuna, A., Eldurssi, O., Elfeki, H., Elhadi, M., Elhassan, M., Elhissi, A., Elliot, B., Elsenbroek, C., Elsolh, B., Elson, N., Eltyeb, H., Emerson, H., Emile, S. H., Endalle, G., English, W., Ercisli, C., Espinosa, G., Essam Abdelraheem, M., Essangri, H., Etienne, P., Evans, M. D., Evans, T., Ezeme, C., Ezzahraa, F., Fadalla, T., Fagan, J., Fahmy, M., Fairfield, C., Falade, O., Famularo, S., Faqar-Uz-Zaman, F., Farid, Y., Farooq, A., Farooq, H., Farooqui, F., Farquharson, B., Faruqi, A., Faulder, R., Faut, M., Fechner, K., Feenstra, T., Fehervari, M., Fernandez, L., Ferna´ ndez Alberti, J., Ferrario, L., Field, D., Fiore, L., Fingerhut, S., Finlayson, S., Fleming, N., Fleming, C., Florial, E., Fok, M., Fokin, D., Foley, M., Forero, M. P., Forgan, T., Fornasiero, M., Fowler, H., Fowler, G., Franchi, E., Franklin, L., Fredriksson, A˚., Fruhling, P., Fuentes Navarrette, G., Fu¨ lo¨ p, A., Furtado, M., Gaarder, T., Galbraith, N., Gallagher, I. T. K., Gallo, G., Gana, T., Gaskin, E., Gasparini, M., Gatan, R. G., Geary, E., Gelaye Wudineh, K., Gemenetzis, G., Georgi, M., Ghalige, H., Ghareeb, W., Ghatwary Tantawy, T., Ghomsi, C., Ghuman, A., Giannakis, P., Giron, F., Gjengedal, K., Gkotsis, E., Glasbey, J., Godahewa, S., Godula, D., Goffredo, P., Goh, S., Golriz, M., Gomez, L., Gomez Gomez, D., Gonzalez, R., Gonzalez, D., Gonzalez Gutierrez, E., Gopar, D., Gordini, L., Gori, A., Gorta´ zar, S., Gousy, N., Gowda, R., Gowda, M., Gqada, J., Grechenig, M., Greer, J., Grego´ rio, L., Grigorova, A., Grimes, H., Groot, V., Grossman, R. C., Gruber, R., Gru¨ ter, A., Guest, R., Gujjuri, R., Gu¨ lc¸ek, E., Gulcu, B., Gull, K., Gulmez, M., Gupta, V., Gutlic, A., Guven, T., Gwatirisa, T., Gwini, G., Gwodog, P., Gysling, S., Habib, M., Hafeez Bhatti, A. B., Hallesmith, J., Halloran, S., Hamza Sadiq, M., Haney, C., Hanna, N., Hanna, L., Hannington, M., Harbjerg, J., Haribaskaran, D., Harran, N., Harrington, B., Harrison, E., Hasan, R., Hashmi, S., Hassan, M., Hassan, A., Haverkamp, L., Hazen, S., Heer, B., Heil, J., Helliwell, J., Henriksen, N., Henshall, D., Hermanson, M., Hermena, S., Hettiarachchi, D., Hextall, C., Hidalgo, M., Hidayat, H., Hider, A., Higgins, P., Hinchliffe, R., Hirani, D., Hirpara, D., Hisham, I., Hite, M., Hoh, S. M., Holmberg, C., Ho¨ lmich, E., Holst, F., Hossam, A., Hossam Elfallal, A., Howard, P., Huaman, E., Huang, Y., Huang, L., Huang, D., Huber, T., Hugh, J., Hughes, J., Hu¨ ttner, F., Huynh, R., Hylands, A., Iannuzzi, J., Ielpo, B., Iftikhar Talib, A., Ignacio, J., Ignatavicius, P., Ike, S., Ikwu, C., Inama, M., Ing, A., Ingels, A., Isik, A., Islam, N., Ives, I. J., Alhasan, A. J. M. S., Perez Rivera, C. J., Ja´ come, F., Jaffer, T., Jagiella-Lodise, O., Jain, M., Jain, K., Jakubauskas, M., Jalal, M., James, H., Jang, Y., Janssen, B., Jansson, H., Jariod-Ferrer, U´., Javanmard, H., Javed, S., Jayarajah, U., Jayasuriya, I., Je, J., Jessop, Z., Jia Lin Tang, E., Jiang, H., Jiayan, Y., Jih Huei, T., Jimenez-Rodriguez, R., Joh, D., Johnson, A., Jones, N., Jones, C., Jordan, C., Jose´ Nu´ nez Ju, J., Jose´ Pizarro, ~ M., Joseph, C. Jose Salazar J., Justiniano, C., Kabir, T., Kadhum, M., Kalfountzos, C., Kalogiannaki, E., Kalyanasundaram, K., Kamarajah, S., Kamil Quraishi, M., Kanemitsu, Y., Kapila, A., Kapila, V., Karagiannidis, G., Kashif, M., Kathiravelupillai, S., Kathiravelupillai, A., Katsogridakis, E., Kaur, K., Kaur Sekhon Inderjit Singh, H., Kausur, N., Kawka, M., Keehan, G., Kehlet Watt, S., Kelly, M., Kelly, M. E., Kelvin Egbuchulem, I., Kembuan, G., Khajeh, E., Khaled Elfaitur, A., Khan, M. F., Khan, S., Khan, M., Khan, D., Khan, H., Khatkar, H., Khatkov, E., Khaw, R., Kim, B., Kishore Siddiraju, K., Kitua, D., Kırımtay, B., Kmezic, S., Knight, S., Koe¨ter, T., Koh, A., Koh Hong Xiang, F., Kojo Anyomih, T., Kok, A. I. N., Kokelaar, R., Koliarakis, I., Kolli, S., Kong, J., Ko¨ nig, D., Otze, M., Kourdouli, A., Kowal, M., Kraima, A., Kramer, F., Kryzauskas, M., Kuchynskyi, I., Kuemmerli, C., Kuiper, S., Kumar, S., Kumar, A., Kumar, L., Kumar, H., Kumar, N., Kumar Bandyopadhyay, S., Kumar Garg, P., Kumar Venkatappa, S., Kung, J., Kural, S., Kushairi, A., Kuuzie, E., Kvietkauskas, M., Kwek, I., La, J., Lai, L., Lakpriya, S., Lam, K., Lami, M., Lansdorp-Vogelaar, I., Lapolla, P., Larsen, H., Latif, J., Laudari, U., Laurnezi, A., Lawal, A., Lawday, S., Lederhuber, H., Lednev, A., Lee, R., van Leerdam, M. E., Lefevbre, G., Lesmus, M., Leyva Moraga, F. A., Leyva Moraga, E., Leyva Moraga, F., Li, H. L., Li, A., Li, Z., Licardie, E., Light, A., Lightner, A. L., Lin, A., Lincango, E., Litta, F., Liu, H., Lofthouse, B., Londono, M. A., Lopes, R., Lopes de Freitas, R., Lopez, L., Lo´ pez, A. I., ~ Lopez-Gomez, J., Lopez-Pena, G., Lowe, R., Lowe, D., Lowey, M., Loy, G., Lozanovski, V., Luzon, J., Lynn, P., Maccabe, T., Machielsen, A., Mafla Herrerı´a, C. A., Maggino, L., Mahawar, K., Mahmood, D., Mahmoud, M., Mahtani, K., Maitra, I., Maji, S., Majiet, I., Mal, L., Malherbe, J., Malhotra, K., Malkomes, P., Man, E., Manan Sheikh, A., Manjunath, S., Manzano Nunez, R., Manzoor, S., Maqsood, R., ~ Marchegiani, G., Marchegiani, F., Marı´n, D., Marin, A., Marks, I., Marson, E., Martensen, A., Martin, D., Martı´n Martı´n, G., Martin-Perez, B., Martinez, P., Marwaha, P., Mashauri, C., Mashbari, H., Masior, Ł., Masri, R., Masud, L., Masudi, S., Mateu Calabuig, G., Math, S., Matrachisia, A., Mayol, J., Mazingi, D., Mazzotta, A., Mcalinden, J., Mccabe, G., Mccolm, L., Mcelvaney, H., Mcgivern, K., Mcgovern, J., Mcguinness, E., Mcinerney, N., Mckay, S., Mckee, C., Mckenna, M., Mckenna, N., Mclean, K., Mediratta, S., Medkova, Y., Medzhidov, O., Mehraj, A., Mekhael, M., Mekinde, O., Mellenthin, C., Melucci, A., Mentor, K., Merchant, J., Messias, H., Messeha, M., Meza, C., Mhango, P., Miladinov, M., Milagros Niquen Jimenez, M., Miller, P., Mills, E., Milton, A., Minayeva, O. A., MinHua Zheng, Z., Mischlinger, H., Mo¨ ckli, B., Modi, R., Mohamed, H. M., Mohamed, M., Mohamed Abulghasm, T., Mohammad, S. A., Mohammed, T. O., Mohammed, A., Mohan, H., Mohan, M., Moin, I., Mok, V., Molina, G., Moloney, J., Moneim, J., Monfort Mira, M., Montcusı´ Ventura, B., Montouri, M., Moossdorff, M., Mora-Guzma´ n, I., Moran, B., Mora´ n, R. A. R., Moreno-Ordaz, S., Morera, A´., Morgan, R., Morley, R., Moro-Valdezate, D., Moros, S., Moss, J. -L., Morven, A., Morton, D., Moynihan, A., Moyo´ n, M., Muduli, N., Mugla, N., Mugla, W., Mu¨ ller, P., Mun, G., Mundhada, R., Munir, I., Munoz, F., Mu ~ noz, E., Mu ~ noz, A., Munoz Balderas, D. ~ C., Murgitroyd, E., Murray, V., Murthy, S., ~ Mushiwokufa, W., Mustafa, H., Mustakimov, B., Mutambanengwe, P., Myint, P., Nadkarni, S., Naess, P. A., Nahar, S., Naidoo, P., Nam, R., Nandhra, S., Nanjappa, N., Narasimhan, V., Nardi, W., Nasir, M., Naughton, A., Naumann, D., Navarro, S., Nawaaz Karimbocus, M., Nazir, A., Ndereya, S., Ndong, A., Negoi, I., Nel, D., Nelson, D., Nepal, S., Nugent, T., Nepogodiev, D., Neufeld, J., Ng, J., Ng, D., Ng, C. E., Ngaserin, S., Ngu, L., Ngwenya, E., Fhearaigh, R. N., Nikolousakis, T. -K., Ninkovic, M., Nita, G., Nitschke, C., Noren, E., Noton, T., Novikova, A., Nowinka, Z., Nyakunengwa, T., Nyalundja, A., Nzenwa, I., Ø Kristensen, H., O’Brien, C., O’Brien, L., O’Brien, S., O’Reilly, J., O’Rourke, S., O’Sullivan, M., O’Dwyer, M., Ochieng, L., Oderoha, E., Oh, K. E., O¨ hlberger, L., O¨ lc¸u¨ m, M., Olkina, A., Omkumar, M., Omnitel, B., Oncel Yakar, D., Ong, K., Ong Wei Lin, L., Ooi, R., Ooi, S., Oomman, A., Oon Tyjet, D., Opiyo, S., Oscullo Yepez, J. J., Osei-kuffour, N., Osunronbi, T., Ottlaka´ n, A., Oussama Kacimi, S., Ovaere, S., Ozair, A., Pachler, F., Pai Oo, S., Paiella, S., Panaiotti, L., Panda, N., Pandarinath, S., Pandey, D., Pandrowala, S., Papa Mamadou, F., Paranathala, M., Park, J., Parmar, C., Parvez, A., Pasovic, L., Pasquer, A., Pasumarthy, N., Pata, F., Patel, T., Patel, P., Patel, N., Patel, M., Patron Uriburu, N., Patrone, R., Paul, A., Pavan Kumar, O. M., Pavithran, A., Pedraza Ciro, M., Pellino, G., Peloso, A., Pena~ Gallardo, M. T., Pena Velazquez, A., Perea, J., Pe´rez-Sa´ nchez, L. E., ~ Perra, T., Perrotta, G., Petersson, P., Petra, G., Petrucciani, N., Pickin, C., Pino, V., Pinotti, E., Pinto, F., Plum, P., Podesta, F., Pollini, T., Pompeu Sa´, M., Ponce Leon, F., Ponniah, H. S., Ponte de Sousa, X., Ponton, J., Pontula, A., Popa, M., Portilla, A. L., Posner, F., Post, S., Potolicchio, A., Pouwels, S., Povo, A., Prasad, P., Preciado, S., Preece, R., Proud, D., Pulido Segura, J. A., Puliyath, N., Qui, M., Quimbaya Rodrı´guez, A. S., Raby-Smith, W., Racovit¸a, A., Rad, A., Radwan, R., Rafaih Iqbal, M., Rafik, A., Raguan, B., Rahi, M., Rahiri, J. -L., Rahme, J., Rai, L., Raj, A., Raj Saksena, A., Raja, M., Ramirez, J., Ramzi, J., Ranstam, J., Rao, C., Rashid, A., Ratnayake, B., Rattanasirivilai, K., Raubenheimer, K., Ravikumar, N., Ravn, S., Razoz, N., Rea, W., Regan, A., Rela, M., Remme, A., Rey Chaves, C. E., Reyes, A., Riad, A., Rice, D., Rios Quintana, K., Ritter, A., Roalsø, M., Robinson, D., Rodriguez, J., Rodrı´guez, F., Rodriguez, M. C., Rogers, A., Rohila, J., Romanyuc, D., Romic, I., Rommaneh, M., Rompianesi, G., Rosa, F., Roscio, F., Rose, A., Rotimi, T., Ruiz, H., Ruiz Yucuma, J., Ruiz-U´ car, E., Ruslan, M., Rutega˚ rd, M., Ryan Harper, E., Ryckx, A., Rydbeck, D., Fonseca, E., Sanchez Teran, A., Sanchez Ussa, S., Sandli, O., Sanfey, H., Sanghera, J., Sani, I., Santafe Guerrero, M., Sante Fornasiero, M., Santes Jasso, O., Santos Pereira, I., Santos Sousa, H., Saratzis, A., Sarmiento Alarcon, A., Saumtally, T., Sayyed, R., Schettino, M., Schleimer, L., Schmidt, T., Schondffelt, K., Schwab, M., Scott, A., Searle, H., Sebopelo, L., Seeglier, B., Seishima, R., Semenvov, D., Senent-Boza, A., Sepulveda, J., Serenari, M., Serrano Navidad, M., Sert, I., Sewart, E., Sgro`, A., Shadrina, V., Shah, K., Shahid, F., Shalaby, M., Shankar, B., Shapiro, J., Sharma, L., Sheel, A., Shenfine, A., Shenoy, S., Sherif, A., Shetty, N., Shetty, R., Sia, T. C., Sichimba, D., Siddique, H., Siddiqui, I., Simkens, G., Simoe, J., Simon, H., Sinan, L., Singh, T., Singh, K., Singh, Y., Sinha, L., Siragusa, L., Sluckin, T., Smart, Y. W., Smith, H., Smith, K., Smits, L., Sneep-van Kessel, C., Sohrabi, C., Solo´ rzano Pineda, O., Soma, A., Sooriyapiragasam, L., Søreide, K., Sparavigna, M., Spence, R., Spencer, N., Spiers, H., Spinelli, A., Sprakel, J., Sravanam, S., Srinivasan, M., Srinivasan, R., Staniszewska, A., Stanworth, S. J., Stasinos, K., Steele, R. J. C., Steinholt, I., Steinruecke, M., Stephen, B. -J., Stijns, J., Still, M., Stupalkowska, W., Subba, S., Subbotin, V. V., Sucharitkul, P., Sudarsanam, A., Sudhamsh Reddy, D., Suhardja, T., Suliman, M., Sund, M., Sunilkumar, A., Suresh, N., Sussmes, S., Sutton, P., Syltern, J., Taha, A., Takamizawa, Y., Takoutsing Dongmo, A. B., Tama´ s, T., Tan, L., Tan, J. L., Tan, K., Tan, E., Tan Yong Hui, A., Tanase, A., Tariverdiev, A., Tasnem, A., Tatar, C., Tay, E., Tejedor, P., Tesfaye, G., Tetinou, F., Thorpe, C., Thyø, A., Tlelo Amastal, D., Tolani, M., Tolga Saracoglu, K., To¨ lgyes, T., Tong, J., Torrent Jansa`, L., Toscano Igartua, S., Tovani Palone, M. R., Traff, H., Trevis, J., Tummers, W., Tur, A., Turchenko, I., Uche, V., Uddin, A., Udonsak, N., Ullah, M., Urbonas, T., Uwins, C., Uy Magadia, E., Uzair Qureshi, A., Uzun, K., Vadim, P., Valarche, G., Valdez Gonzalez, R. A., Vallee, M., van Beek, D. -J., van Dalen, A. S., van den Hondel, D., van der stok, E., van Dorp, M., van Oostendorp, S., van Praag, E., van Rees, J., van Silfhout, L., Varga, Z., Varghese, S., Varghese, C., Varghese, J., Vasilica, A. -M., Va´ squez Ojeda, X., Vega, E., Vehler, S., Venchiarutti, R., Vengatesan, S., Venn, M., Verma, D., Vianey Partida Nava, G., Victoria, D., Vieira, P., Vilar Alvarez, M. E., Vinci, D., Viscasillas Palla` s, G., Viswanath, M., Vivanco, J., Vizcaya Rodrı´guez, V., Vo, J., Volchanski, D., Voron, T., Voronovskyi, Y., Vu, J., Wadhwa, M., Wadhwa, S., Wagner, G., Wallace, M., Wang, Y. Y., Wang, J., Wani, A., Wanigasooriya, K., Wanjara, S., Wanjiku, N., Warner, C., Wei Leow, T., Weiser, T., Weisters, M., Wellington, M. J., Wells, C., Wenzelberg, C., Wettstein, D., Wezel, A., Wheldon, L., Widmer, L., Wilson, M., Wigmore, S., Wijayaratne, T., Wijeyaratne, M., 1176 | BJS, B. P. L., 108, Vol., 10 Sá-Marta, No., Sadien, I., Safarinteranya, D., Sagoo, K., Sakata, S., Saladino, E., Saleem, A., Saleem, S., Salehi, M., Salih, S., Sallinen, V., Salvans, S., Sam, Z. H., Samadov, E., Sampaio Alves, M., Sanad, A., Sánchez Wijnhoven, S., Wilkin, R., Williams, E., Willis, F., Winter, D., Wirsik, M. M., Wishah, B., Wong, G., Wong, W. J., Wong, K., Wong, K. -Y., Worku, D., Wright, E., Wright, J., Wroe Wright, O., Xenacki, S., Xia, W., Xu, W., Xu, Z., Yalcinkaya, A., Yang, W., Yang, P. -C., Yanishev, A., Yanzon de la Torre, A., Yao, H., Yaqoob, E., Yen Ling Quake, S., Yeo, D., Yeom, B., Yershov, D., Yiasemidou, M., Yildiz, A., Yiu, A., Yoav, M., Yong, E., Yoshimura, R., Younis, M. U., Younis Ringshawl, Z., Youssef, M., Yue, Y., Yuen, S., Yuldashev, R., Yurttas, C., Yves, B., Zaborowski, A., Zackeri, R., Zafar, A., Zahra, W., Zaidi, A., Zainudin, S., Zakeri, R., Zamora, I., Zamora, A. T., Zawistowski, M., Zbikowska, G., Zegers, W., Zehra, S., Zeyra, A., Zhagniyev, Z., Zhukova, L. G., Zivanovic, M., Zmuc, J., Zope, M., Zubayraeva, A., Zucker., B., Abahuje, E, Abbas, A, Abd El Aziz Abd El Maksoud, M, Abdelhady, A, Abdelhamid, S, Abdelkarem Ahmed Faraj, H, Abdelqader, B, Abdelrahman, T, Abdou, H, Abdullah, A, Abedua Harrison, M, Abem Owusu, E, Aboalazayem, A, Aboulhosn, R, Abu Oda, S, Abubakar, A, Abutaka, A, Acevedo Fontalvo, D, Acuna, S, Adefemi, A, Adegbola, S, Adenuga, T, Adeyeye, A, Adil Hilmi, A, Adisa, A, Aditya, K, Adjeso, T, Aftab, R, Afzal, A, Aggarwal, V, Aggarwal, A, Aguilera, R, Aguilera-Arevalo, M, Aguirre Salamanca, E, Aguirre-Allende, I, Ahari, D, Ahmad, H, Ahmad Rauf, F, Ahmad Zartasht Khan, A, Ahmed, S, Ahmed Fieturi, N, Ahmed Mohamed, S, Ahmed-Bakhsh, Z, Ahsan Javed, M, Akano, L, Akbar, A, Akhbari, M, Akhmedov, P, Aksit, G, Akula, Y, Alagaratnam, A, Al Majid, S, Al Mukhtar, O, Al Omran, H, Alasali, N, Al-Azzawi, M, Al-Habsi, R, Al-Iraqi, H, Al-Naggar, H, Alameer, E, Albirnawi, H, Alderson, D, Aldulaijan, F, Alejandro Miranda Ojeda, R, Alhasan, A, Ali, S, Ali, A, Ali Khan, M, Alimova, Y, Aljanadi, F, Aljubure, R, Allopi, N, Almedbal, H, Almubarak, M, Alqaidoom, Z, Alselaim, N, Alshaar, M, Alshammari, R, Altaf, K, Altiner, S, Altunpak, B, Alvarez Lozada, L, Amal Nahal, E, Amer, A, Amin, K, Aminu, U, Amisi Numbi, N, Amjad, T, Amoah, R, An, Y, Anastasopoulos, N, Andres Urrutia, J, Angarita, F, Angarita, K, Angel Freiria Eiras, M, Antypas, A, Anwar, M, Anwar, H, Apampa, T, Apostolou, K, Aquina, C, Arachchige Adithi Himika Randeni, R, Archila Godinez, M, Arez, O, Arezzo, A, Armonis, P, Arshad, S, Arshad Salman, M, Arshid, A, Arteaga Asensio, P, Arthur, T, Arumuga Jothi, A, Aryo Damara, F, Asensio Gomez, L, Ashcroft, J, Ashraf, S, Asif, A, Atif, M, Attaullah Khan, M, Avellaneda, N, Awad, S, Awadh, M, Axiaq, A, Ayad Mohammed Shuwayyah, A, Ayalew, D, Aytac, E, Azam, F, Azevedo, J, Azhar, B, Aziz, J, Aziz, A, Azzam, A, Baba Ndajiwo, A, Baig, M, Baker, D, Bakko, F, Balachandran, R, Balachandran, G, Balagizi Mudekereza, J, Balai, E, Balci, B, Balduzzi, A, Balhareth, A, Bandyopadhyay, S, Banerjee, D, Bangalore Mahalinga, D, Bankhead-Kendall, B, Bankole, N, Banwell, V, Baris Bengur, F, Baris Ozmen, B, Barnard, M, Barnett, R, Barreras Espinoza, J, Barrios, A, Bass, G, Bass, M, Bausys, A, Bavikatte, A, Bayram, J, Belousov, M, Berardi, A, Beamish, A, Beattie, C, Belia, F, Bellato, V, Bellikatti, S, Benjamens, S, Benlice, C, Bennedsgaard, S, Bennett, S, Bentounsi, Z, Bergenfeldt, H, Bergenfelz, A, Besselink, M, Bhandoria, G, Bhangu, E, Bhatia, M, Bhatti, M, Bilgili, Z, Bislenghi, G, Bisset, C, Biswas, S, Blake, J, Blanco, R, Boccalatte, L, Boden, R, Bojanic, C, Boland, M, Boland, P, Bollen, E, Bonci, E, Boni, L, Booth, A, Booth, R, Borakati, A, Borunda Escudero, G, Bosco, S, Bostrom, P, Botelho De Alencar Ferreira Cruz, P, Bouchagier, K, Bouhuwaish, A, Boutros, M, Boyce, K, Boyle, C, Bradshaw, L, Brandl, A, Brar, A, Brat, G, Brenkman, H, Brennan, C, Brines, C, Brookmyre, A, Brosnan, C, Brouwers, L, Brown, A, Brown, L, Brown, C, Brown, J, Bs, V, Buksh, M, Bunani Emmanuel, M, Burbano, D, Burelli, A, Burke, A, Burke, J, Burlov, N, Burns, A, Burton, O, Butt, A, Buzra Ozkan, B, Cabrera Silva, L, Caicedo, E, Calderbank, T, Cambridge, W, Campelo, G, Can Tatar, O, Carbone, F, Carrano, F, Casallas, D, Casanova Portoles, D, Casciani, F, Cassimjee, I, Castaneda Ramirez, O, Catalan, V, Caviedes, J, Cayetano, L, Ceresoli, M, Chan, M, Chan, V, Chandrasinghe, P, Chapman, S, Chaturvedi, A, Chaudhry, D, Chaudry, H, Chen, H, Cheng, A, Chernykh, M, Cherrie, A, Cheruiyot, I, Cheung, J, Chia, C, Chica, J, Chinai, N, Chirwa, A, Chiwaligo, J, Choi, A, Choi, J, Chowdhury, M, Christopher, E, Christou, N, Chu, T, Chua, D, Chua, H, Chung, C, Cihat Yildirim, A, Cillo, M, Cioffi, S, Claireaux, H, Clermonts, S, Clifford, R, Climent, M, Clynch, A, Coelen, R, Colas-Ruiz, E, Collar, A, Collard, M, Conlon, K, Connelly, T, Connor, K, Cook, J, Correia De Sa, T, Cosgun Acar, N, Costa, T, Couch, D, Cowper, S, Creavin, B, Crook, B, Curell, A, D'Alessio, R, Dale, J, Damgaard Eriksen, J, Dario Martin Gonzalez, I, Darwish, A, Das, M, Das, R, Das, K, Dave, R, David, S, Davies, T, Davis, C, Davison, S, Davletshina, V, Dawidziuk, A, Dawson, A, De Andres Crespo, M, De Berker, H, De Dieu Ngo, P, Dekker, E, De La Caridad Espinosa Luis, R, De Lacy, B, Demartines, N, De Montserrat Medina Sifuentes, A, De Silva, S, Del Rio, C, Delaune, V, Dell, A, Demirbas, I, Demirli Atici, S, Deniz Tepe, M, Derebey, M, Desai, G, Desai, M, Devarakonda, S, Deveras, N, Di Franco, G, Di Martino, M, Di Marzo, F, Diaz, A, Diaz Del Gobbo, G, Diazcastrillon, C, Dick, L, Dickinson, K, Diego, E, Dimasi, I, Ding, A, Dingemans, S, Dixon, L, Dixon, B, Doherty, W, Dooreemeah, D, Donohue, C, Dornseifer, M, Dossa, F, Dossou, W, Drake, T, Drami, I, Drevin, G, Du Plessis, M, Dudi-Venkata, N, Dudley, R, Duffy, S, Duklas, D, Dumbrava, B, Duygu Avlar, F, Dworzynska, A, Ebrahim, W, Ebrahim, A, Efren Lozada Hernandez, E, Ehigie, N, El Boghdady, M, El Hasnaoui, C, El Sheikh, M, El-Hussuna, A, Eldurssi, O, Elfeki, H, Elhadi, M, Elhassan, M, Elhissi, A, Elliot, B, Elsenbroek, C, Elsolh, B, Elson, N, Eltyeb, H, Emerson, H, Emile, S, Endalle, G, English, W, Ercisli, C, Espinosa, G, Essam Abdelraheem, M, Essangri, H, Etienne, P, Evans, M, Evans, T, Ezeme, C, Ezzahraa, F, Fadalla, T, Fagan, J, Fahmy, M, Fairfield, C, Falade, O, Famularo, S, Faqar-Uz-Zaman, F, Farid, Y, Farooq, A, Farooq, H, Farooqui, F, Farquharson, B, Faruqi, A, Faulder, R, Faut, M, Fechner, K, Feenstra, T, Fehervari, M, Fernandez, L, Fernandez Alberti, J, Ferrario, L, Field, D, Fiore, L, Fingerhut, S, Finlayson, S, Fleming, N, Fleming, C, Florial, E, Fok, M, Fokin, D, Foley, M, Forero, M, Forgan, T, Fornasiero, M, Fowler, H, Fowler, G, Franchi, E, Franklin, L, Fredriksson, A, Fruhling, P, Fuentes Navarrette, G, Fulop, A, Furtado, M, Gaarder, T, Galbraith, N, Gallagher, I, Gallo, G, Gana, T, Gaskin, E, Gasparini, M, Gatan, R, Geary, E, Gelaye Wudineh, K, Gemenetzis, G, Georgi, M, Ghalige, H, Ghareeb, W, Ghatwary Tantawy, T, Ghomsi, C, Ghuman, A, Giannakis, P, Giron, F, Gjengedal, K, Gkotsis, E, Glasbey, J, Godahewa, S, Godula, D, Goffredo, P, Goh, S, Golriz, M, Gomez, L, Gomez Gomez, D, Gonzalez, R, Gonzalez, D, Gonzalez Gutierrez, E, Gopar, D, Gordini, L, Gori, A, Gortazar, S, Gousy, N, Gowda, R, Gowda, M, Gqada, J, Grechenig, M, Greer, J, Gregorio, L, Grigorova, A, Grimes, H, Groot, V, Grossman, R, Gruber, R, Gruter, A, Guest, R, Gujjuri, R, Gulcek, E, Gulcu, B, Gull, K, Gulmez, M, Gupta, V, Gutlic, A, Guven, T, Gwatirisa, T, Gwini, G, Gwodog, P, Gysling, S, Habib, M, Hafeez Bhatti, A, Hallesmith, J, Halloran, S, Hamza Sadiq, M, Haney, C, Hanna, N, Hanna, L, Hannington, M, Harbjerg, J, Haribaskaran, D, Harran, N, Harrington, B, Harrison, E, Hasan, R, Hashmi, S, Hassan, M, Hassan, A, Haverkamp, L, Hazen, S, Heer, B, Heil, J, Helliwell, J, Henriksen, N, Henshall, D, Hermanson, M, Hermena, S, Hettiarachchi, D, Hextall, C, Hidalgo, M, Hidayat, H, Hider, A, Higgins, P, Hinchliffe, R, Hirani, D, Hirpara, D, Hisham, I, Hite, M, Hoh, S, Holmberg, C, Holmich, E, Holst, F, Hossam, A, Hossam Elfallal, A, Howard, P, Huaman, E, Huang, Y, Huang, L, Huang, D, Huber, T, Hugh, J, Hughes, J, Huttner, F, Huynh, R, Hylands, A, Iannuzzi, J, Ielpo, B, Iftikhar Talib, A, Ignacio, J, Ignatavicius, P, Ike, S, Ikwu, C, Inama, M, Ing, A, Ingels, A, Isik, A, Islam, N, Ives, I, Al-Hasan, A, Perez Rivera, C, Jacome, F, Jaffer, T, Jagiella-Lodise, O, Jain, M, Jain, K, Jakubauskas, M, Jalal, M, James, H, Jang, Y, Janssen, B, Jansson, H, Jariod-Ferrer, U, Javanmard, H, Javed, S, Jayarajah, U, Jayasuriya, I, Je, J, Jessop, Z, Jia Lin Tang, E, Jiang, H, Jiayan, Y, Jih Huei, T, Jimenez-Rodriguez, R, Joh, D, Johnson, A, Jones, N, Jones, C, Jordan, C, Jose Nunez Ju, J, Jose Pizarro, M, Jose Salazar, C, Joseph, J, Justiniano, C, Kabir, T, Kadhum, M, Kalfountzos, C, Kalogiannaki, E, Kalyanasundaram, K, Kamarajah, S, Kamil Quraishi, M, Kanemitsu, Y, Kapila, A, Kapila, V, Karagiannidis, G, Kashif, M, Kathiravelupillai, S, Kathiravelupillai, A, Katsogridakis, E, Kaur, K, Kaur Sekhon Inderjit Singh, H, Kausur, N, Kawka, M, Keehan, G, Kehlet Watt, S, Kelly, M, Kelvin Egbuchulem, I, Kembuan, G, Khajeh, E, Khaled Elfaitur, A, Khan, M, Khan, S, Khan, D, Khan, H, Khatkar, H, Khatkov, E, Khaw, R, Kim, B, Kishore Siddiraju, K, Kitua, D, Kirimtay, B, Kmezic, S, Knight, S, Koeter, T, Koh, A, Koh Hong Xiang, F, Kojo Anyomih, T, Kok, A, Kokelaar, R, Koliarakis, I, Kolli, S, Kong, J, Konig, D, Koshy, M, Kotze, P, Kourdouli, A, Kowal, M, Kraima, A, Kramer, F, Kryzauskas, M, Kuchynskyi, I, Kuemmerli, C, Kuiper, S, Kumar, S, Kumar, A, Kumar, L, Kumar, H, Kumar, N, Kumar Bandyopadhyay, S, Kumar Garg, P, Kumar Venkatappa, S, Kung, J, Kural, S, Kushairi, A, Kuuzie, E, Kvietkauskas, M, Kwek, I, La, J, Lai, L, Lakpriya, S, Lam, K, Lami, M, Lansdorp-Vogelaar, I, Lapolla, P, Larsen, H, Latif, J, Laudari, U, Laurnezi, A, Lawal, A, Lawday, S, Lederhuber, H, Lednev, A, Lee, R, Van Leerdam, M, Lefevbre, G, Lesmus, M, Leyva Moraga, F, Leyva Moraga, E, Li, H, Li, A, Li, Z, Licardie, E, Light, A, Lightner, A, Lin, A, Lincango, E, Litta, F, Liu, H, Lofthouse, B, Londono, M, Lopes, R, Lopes De Freitas, R, Lopez, L, Lopez, A, Lopez-Gomez, J, Lopez-Pena, G, Lowe, R, Lowe, D, Lowey, M, Loy, G, Lozanovski, V, Luzon, J, Lynn, P, Maccabe, T, Machielsen, A, Mafla Herreria, C, Maggino, L, Mahawar, K, Mahmood, D, Mahmoud, M, Mahtani, K, Maitra, I, Maji, S, Majiet, I, Mal, L, Malherbe, J, Malhotra, K, Malkomes, P, Man, E, Manan Sheikh, A, Manjunath, S, Manzano Nunez, R, Manzoor, S, Maqsood, R, Marchegiani, G, Marchegiani, F, Marin, D, Marin, A, Marks, I, Marson, E, Martensen, A, Martin, D, Martin Martin, G, Martin-Perez, B, Martinez, P, Marwaha, P, Mashauri, C, Mashbari, H, Masior, L, Masri, R, Masud, L, Masudi, S, Mateu Calabuig, G, Math, S, Matrachisia, A, Mayol, J, Mazingi, D, Mazzotta, A, Mcalinden, J, Mccabe, G, Mccolm, L, Mcelvaney, H, Mcgivern, K, Mcgovern, J, Mcguinness, E, Mcinerney, N, Mckay, S, Mckee, C, Mckenna, M, Mckenna, N, Mclean, K, Mediratta, S, Medkova, Y, Medzhidov, O, Mehraj, A, Mekhael, M, Mekinde, O, Mellenthin, C, Melucci, A, Mentor, K, Merchant, J, Messias, H, Messeha, M, Meza, C, Mhango, P, Miladinov, M, Milagros Niquen Jimenez, M, Miller, P, Mills, E, Milton, A, Minayeva, O, MinHua Zheng, Z, Mischlinger, H, Mockli, B, Modi, R, Mohamed, H, Mohamed, M, Mohamed Abulghasm, T, Mohammad, S, Mohammed, T, Mohammed, A, Mohan, H, Mohan, M, Moin, I, Mok, V, Molina, G, Moloney, J, Moneim, J, Monfort Mira, M, Montcusi Ventura, B, Montouri, M, Moossdorff, M, Mora-Guzman, I, Moran, B, Moran, R, Moreno-Ordaz, S, Morera, A, Morgan, R, Morley, R, Moro-Valdezate, D, Moros, S, Moss, J, Morven, A, Morton, D, Moynihan, A, Moyon, M, Muduli, N, Mugla, N, Mugla, W, Muller, P, Mun, G, Mundhada, R, Munir, I, Munoz, F, Munoz, E, Munoz, A, Munoz Balderas, D, Murgitroyd, E, Murray, V, Murthy, S, Mushiwokufa, W, Mustafa, H, Mustakimov, B, Mutambanengwe, P, Myint, P, Nadkarni, S, Naess, P, Nahar, S, Naidoo, P, Nam, R, Nandhra, S, Nanjappa, N, Narasimhan, V, Nardi, W, Nasir, M, Naughton, A, Naumann, D, Navarro, S, Nawaaz Karimbocus, M, Nazir, A, Ndereya, S, Ndong, A, Negoi, I, Nel, D, Nelson, D, Nepal, S, Nugent, T, Nepogodiev, D, Neufeld, J, Ng, J, Ng, D, Ng, C, Ngaserin, S, Ngu, L, Ngwenya, E, Fhearaigh, R, Nikolousakis, T, Ninkovic, M, Nita, G, Nitschke, C, Noren, E, Noton, T, Novikova, A, Nowinka, Z, Nyakunengwa, T, Nyalundja, A, Nzenwa, I, Kristensen, H, O'Brien, C, O'Brien, L, O'Brien, S, O'Reilly, J, O'Rourke, S, O'Sullivan, M, O'Dwyer, M, Ochieng, L, Oderoha, E, Oh, K, Ohlberger, L, Olcum, M, Olkina, A, Omkumar, M, Omnitel, B, Oncel Yakar, D, Ong, K, Ong Wei Lin, L, Ooi, R, Ooi, S, Oomman, A, Oon Tyjet, D, Opiyo, S, Oscullo Yepez, J, Osei-Kuffour, N, Osunronbi, T, Ottlakan, A, Oussama Kacimi, S, Ovaere, S, Ozair, A, Pachler, F, Pai Oo, S, Paiella, S, Panaiotti, L, Panda, N, Pandarinath, S, Pandey, D, Pandrowala, S, Papa Mamadou, F, Paranathala, M, Park, J, Parmar, C, Parvez, A, Pasovic, L, Pasquer, A, Pasumarthy, N, Pata, F, Patel, T, Patel, P, Patel, N, Patel, M, Patron Uriburu, N, Patrone, R, Paul, A, Pavan Kumar, O, Pavithran, A, Pedraza Ciro, M, Pellino, G, Peloso, A, Pena Gallardo, M, Pena Velazquez, A, Perea, J, Perez-Sanchez, L, Perra, T, Perrotta, G, Petersson, P, Petra, G, Petrucciani, N, Pickin, C, Pino, V, Pinotti, E, Pinto, F, Plum, P, Podesta, F, Pollini, T, Pompeu Sa, M, Ponce Leon, F, Ponniah, H, Ponte De Sousa, X, Ponton, J, Pontula, A, Popa, M, Portilla, A, Posner, F, Post, S, Potolicchio, A, Pouwels, S, Povo, A, Prasad, P, Preciado, S, Preece, R, Proud, D, Pulido Segura, J, Puliyath, N, Qui, M, Quimbaya Rodriguez, A, Raby-Smith, W, Racovita, A, Rad, A, Radwan, R, Rafaih Iqbal, M, Rafik, A, Raguan, B, Rahi, M, Rahiri, J, Rahme, J, Rai, L, Raj, A, Raj Saksena, A, Raja, M, Ramirez, J, Ramzi, J, Ranstam, J, Rao, C, Rashid, A, Ratnayake, B, Rattanasirivilai, K, Raubenheimer, K, Ravikumar, N, Ravn, S, Razoz, N, Rea, W, Regan, A, Rela, M, Remme, A, Rey Chaves, C, Reyes, A, Riad, A, Rice, D, Rios Quintana, K, Ritter, A, Roalso, M, Robinson, D, Rodriguez, J, Rodriguez, F, Rodriguez, M, Rogers, A, Rohila, J, Romanyuc, D, Romic, I, Rommaneh, M, Rompianesi, G, Rosa, F, Roscio, F, Rose, A, Rotimi, T, Ruiz, H, Ruiz Yucuma, J, Ruiz-Ucar, E, Ruslan, M, Rutegard, M, Ryan Harper, E, Ryckx, A, Rydbeck, D, Sa-Marta, E, Sadien, I, Safari Nteranya, D, Sagoo, K, Sakata, S, Saladino, E, Saleem, A, Saleem, S, Salehi, M, Salih, S, Sallinen, V, Salvans, S, Sam, Z, Samadov, E, Sampaio Alves, M, Sanad, A, Sanchez Fonseca, S, Sanchez Teran, A, Sanchez Ussa, S, Sandli, O, Sanfey, H, Sanghera, J, Sani, I, Santafe Guerrero, M, Sante Fornasiero, M, Santes Jasso, O, Santos Pereira, I, Santos Sousa, H, Saratzis, A, Sarmiento Alarcon, A, Saumtally, T, Sayyed, R, Schettino, M, Schleimer, L, Schmidt, T, Schondffelt, K, Schwab, M, Scott, A, Searle, H, Sebopelo, L, Seeglier, B, Seishima, R, Semenvov, D, Senent-Boza, A, Sepulveda, J, Serenari, M, Serrano Navidad, M, Sert, I, Sewart, E, Sgro, A, Shadrina, V, Shah, K, Shahid, F, Shalaby, M, Shankar, B, Shapiro, J, Sharma, L, Sheel, A, Shenfine, A, Shenoy, S, Sherif, A, Shetty, N, Shetty, R, Sia, T, Sichimba, D, Siddique, H, Siddiqui, I, Simkens, G, Simoe, J, Simon, H, Sinan, L, Singh, T, Singh, K, Singh, Y, Sinha, L, Siragusa, L, Sluckin, T, Smart, Y, Smith, H, Smith, K, Smits, L, Sneep-Van Kessel, C, Sohrabi, C, Solorzano Pineda, O, Soma, A, Sooriyapiragasam, L, Soreide, K, Sparavigna, M, Spence, R, Spencer, N, Spiers, H, Spinelli, A, Sprakel, J, Sravanam, S, Srinivasan, M, Srinivasan, R, Staniszewska, A, Stanworth, S, Stasinos, K, Steele, R, Steinholt, I, Steinruecke, M, Stephen, B, Stijns, J, Still, M, Stupalkowska, W, Subba, S, Subbotin, V, Sucharitkul, P, Sudarsanam, A, Sudhamsh Reddy, D, Suhardja, T, Suliman, M, Sund, M, Sunilkumar, A, Suresh, N, Sussmes, S, Sutton, P, Syltern, J, Taha, A, Takamizawa, Y, Takoutsing Dongmo, A, Tamas, T, Tan, L, Tan, J, Tan, K, Tan, E, Tan Yong Hui, A, Tanase, A, Tariverdiev, A, Tasnem, A, Tatar, C, Tay, E, Tejedor, P, Tesfaye, G, Tetinou, F, Thorpe, C, Thyo, A, Tlelo Amastal, D, Tolani, M, Tolga Saracoglu, K, Tolgyes, T, Tong, J, Torrent Jansa, L, Toscano Igartua, S, Tovani Palone, M, Traff, H, Trevis, J, Tummers, W, Tur, A, Turchenko, I, Uche, V, Uddin, A, Udonsak, N, Ullah, M, Urbonas, T, Uwins, C, Uy Magadia, E, Uzair Qureshi, A, Uzun, K, Vadim, P, Valarche, G, Valdez Gonzalez, R, Vallee, M, Van Beek, D, Van Dalen, A, Van Den Hondel, D, Van Der Stok, E, Van Dorp, M, Van Oostendorp, S, Van Praag, E, Van Rees, J, Van Silfhout, L, Varga, Z, Varghese, S, Varghese, C, Varghese, J, Vasilica, A, Vasquez Ojeda, X, Vega, E, Vehler, S, Venchiarutti, R, Vengatesan, S, Venn, M, Verma, D, Vianey Partida Nava, G, Victoria, D, Vieira, P, Vilar Alvarez, M, Vinci, D, Viscasillas Pallas, G, Viswanath, M, Vivanco, J, Vizcaya Rodriguez, V, Vo, J, Volchanski, D, Voron, T, Voronovskyi, Y, Vu, J, Wadhwa, M, Wadhwa, S, Wagner, G, Wallace, M, Wang, Y, Wang, J, Wani, A, Wanigasooriya, K, Wanjara, S, Wanjiku, N, Warner, C, Wei Leow, T, Weiser, T, Weisters, M, Wellington, M, Wells, C, Wenzelberg, C, Wettstein, D, Wezel, A, Wheldon, L, Widmer, L, Wilson, M, Wigmore, S, Wijayaratne, T, Wijeyaratne, M, Wijnhoven, B, Wilkin, R, Williams, E, Willis, F, Winter, D, Wirsik, M, Wishah, B, Wong, G, Wong, W, Wong, K, Worku, D, Wright, E, Wright, J, Wroe Wright, O, Xenacki, S, Xia, W, Xu, W, Xu, Z, Yalcinkaya, A, Yang, W, Yang, P, Yanishev, A, Yanzon De La Torre, A, Yao, H, Yaqoob, E, Yen Ling Quake, S, Yeo, D, Yeom, B, Yershov, D, Yiasemidou, M, Yildiz, A, Yiu, A, Yoav, M, Yong, E, Yoshimura, R, Younis, M, Younis Ringshawl, Z, Youssef, M, Yue, Y, Yuen, S, Yuldashev, R, Yurttas, C, Yves, B, Zaborowski, A, Zackeri, R, Zafar, A, Zahra, W, Zaidi, A, Zainudin, S, Zakeri, R, Zamora, I, Zamora, A, Zawistowski, M, Zbikowska, G, Zegers, W, Zehra, S, Zeyra, A, Zhagniyev, Z, Zhukova, L, Zivanovic, M, Zmuc, J, Zope, M, Zubayraeva, A, Zucker, B, Aguilera-Arévalo, M -L, Aguirre Salamanca, E J, Al-Asali, N, Altıner, S, Alvarez Lozada, L A, Anastasopoulos, N -A, Andrés Urrutia, J, Angarita, K -L, Ángel FreirÍa Eiras, M, Anwar, M A, Apampa, T O, Archila Godínez, M I, Arteaga Asensio, P C, Bankole, N D A, Barreras Espinoza, J A, Bhatti, M T, Bonci, E -A, Borunda Escudero, G E, Bosco, S J, Boström, P, Botelho de Alencar Ferreira Cruz, P, Caicedo, E Y, Castañeda Ramírez, O A, Catalán, V, Chen, H W, Chowdhury, M R, Chua, H W, Coelen, R -J, Colás-Ruiz, E, Correia de Sá, T, Coşgun Acar, N, D’Alessio, R, David, S O, de Andres Crespo, M, de Berker, H, de Dieu Ngo, P, de la Caridad Espinosa Luis, R, de Lacy, B, de Montserrat Medina Sifuentes, A, del Rio, C, Demirbaş, I, Díaz, Á, Diaz del Gobbo, G, Diaz-Castrillon, C, du Plessis, M C, Dumbrava, B -D, Efrén Lozada Hernández, E, Fernández Alberti, J, Forero, M P, Fredriksson, Å, Fülöp, A, Gatan, R G, Gortázar, S, Gregório, L, Grüter, A, Gülçek, E, Hafeez Bhatti, A B, Hoh, S M, Hölmich, E, Hüttner, F, Alhasan, A J M S, Perez Rivera, C J, Jácome, F, Jariod-Ferrer, Ú, José, J, José Núñez Ju, J, José Pizarro, M, Khan, M F, Kırımtay, B, Kmezić, S, Koëter, T, König, D, Leyva Moraga, F A, Li, H L, Londoño, M A, Lopes de Freitas, R, López, A I, Mafla Herrería, C A, Manzano Nuñez, R, Marín, D, Martín Martín, G, Masior, Ł, Möckli, B, Mohamed, H M, Mohammad, S A, Mohammed, T O, Montcusí Ventura, B, Mora-Guzmán, I, Morán, R A R, Morera, Á, Moss, J -L, Moyón, M, Müller, P, Muñoz, F, Muñoz, E, Muñoz, A, Muñoz Balderas, D C, Ng, C E, Fhearaigh, R N, Nikolousakis, T -K, Kristensen, H Ø, O’Brien, L, O’Brien, S, O’Reilly, J, O’Rourke, S, O’Sullivan, M, O’Dwyer, M, Oh, K E, Öhlberger, L, Ölçüm, M, Oscullo Yepez, J J, Osei-kuffour, N, Ottlakán, A, Pavan Kumar, O M, Peña Gallardo, M T, Peña Velazquez, A, Pérez-Sánchez, L E, Pompeu Sá, M, Ponniah, H S, Ponte de Sousa, X, Portilla, A L, Pulido Segura, J A, Quimbaya Rodríguez, A S, Racoviţă, A, Rahiri, J -L, Rey Chaves, C E, Roalsø, M, Rodríguez, F, Rodriguez, M C, Ruiz-Úcar, E, Rutegård, M, Sá-Marta, E, Sam, Z H, Emile, Sameh H, Sánchez Fonseca, S, Sgrò, A, Sia, T C, Smart, Y W, Sneep-van Kessel, C, Solórzano Pineda, O, Stephen, B -J, Takoutsing Dongmo, A B, Tamás, T, Tan, J L, Thyø, A, Tölgyes, T, Torrent Jansà, L, Tovani Palone, M R, Valdez Gonzalez, R A, van Beek, D -J, van Dalen, A S, van den Hondel, D, van der stok, E, van Dorp, M, van Oostendorp, S, van Praag, E, van Rees, J, van Silfhout, L, Vasilica, A -M, Vásquez Ojeda, X, Vilar Alvarez, M E, Viscasillas Pallàs, G, Vizcaya Rodríguez, V, Wang, Y Y, Wellington, M J, Wirsik, M M, Wong, W J, Wong, K -Y, Wright, O Wroe, Yang, P -C, Yanzon de la Torre, A, Younis, M U, Zamora, A T, and Surgery
Subjects: Adult, Male, medicine.medical_specialty, Biomedical Research, Coronavirus disease 2019 (COVID-19), International Cooperation, Practice Patterns, Commission, Global Health, Health Services Accessibility, Perioperative Care, Education, Surgeon, COVID-19, surgery, perioperative care, Medical, Pandemic, Humans, Medicine, Practice Patterns, Physicians', Graduate, Pandemics, Surgeons, Health Resource, Infection Control, Physicians', Surgical Procedures, business.industry, General surgery, Middle Aged, Operative, Education, Medical, Graduate, Surgical Procedures, Operative, Perioperative care, Health Resources, Surgery, Female, business, Human
Abstract: Background Coronavirus disease 2019 (COVID-19) was declared a pandemic by the WHO on 11 March 2020 and global surgical practice was compromised. This Commission aimed to document and reflect on the changes seen in the surgical environment during the pandemic, by reviewing colleagues’ experiences and published evidence. Methods In late 2020, BJS contacted colleagues across the global surgical community and asked them to describe how severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) had affected their practice. In addition to this, the Commission undertook a literature review on the impact of COVID-19 on surgery and perioperative care. A thematic analysis was performed to identify the issues most frequently encountered by the correspondents, as well as the solutions and ideas suggested to address them. Results BJS received communications for this Commission from leading clinicians and academics across a variety of surgical specialties in every inhabited continent. The responses from all over the world provided insights into multiple facets of surgical practice from a governmental level to individual clinical practice and training. Conclusion The COVID-19 pandemic has uncovered a variety of problems in healthcare systems, including negative impacts on surgical practice. Global surgical multidisciplinary teams are working collaboratively to address research questions about the future of surgery in the post-COVID-19 era. The COVID-19 pandemic is severely damaging surgical training. The establishment of a multidisciplinary ethics committee should be encouraged at all surgical oncology centres. Innovative leadership and collaboration is vital in the post-COVID-19 era.
Published: 2021

120. Additional file 1 of Reproductive fluids, used for the in vitro production of pig embryos, result in healthy offspring and avoid aberrant placental expression of PEG3 and LUM

Author: E. París-Oller, S. Navarro-Serna, C. Soriano-Úbeda, J. S. Lopes, C. Matás, S. Ruiz, R. Latorre, O. López-Albors, R. Romar, S. Cánovas, and Coy, P.
Abstract: Additional file 1: Table S1. Primers sequences for quantitative real-time PCR.
Published: 2021
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121. Usefulness of strain imaging to determine prognosis in pulmonary hypertension

Author: C Arellano-Serrano, P Remior, Juan Francisco Oteo, S Garcia-Gomez, A Martinez Mingo, D Garcia-Rodriguez, Arturo García-Touchard, Susana Mingo, J.F Goicolea, F. Hernandez Perez, A Borrego, S Navarro, Eusebio García-Izquierdo, and V Monivas Palomero
Subjects: Heart transplantation, medicine.medical_specialty, Univariate analysis, Ejection fraction, business.industry, medicine.medical_treatment, medicine.disease, Pulmonary hypertension, Internal medicine, Medical imaging, medicine, Cardiology, Systole, Cardiology and Cardiovascular Medicine, business, Pulmonary wedge pressure, Survival analysis
Abstract: Introduction Pulmonary hypertension (PH) is defined as mean pulmonary arterial pressure (mPAP) ≥25 mmHg at rest, measured by right heart catheterization (RHC). Purpose To describe classical and myocardial deformation echocardiographic parameters in patients with established PH and to identify prognostic variables Methods We prospectively enrolled 76 patients with mPAP ≥25 mmHg undergoing RHC between 2017 and 2018. All subjects underwent transthoracic echocardiography (TTE) according to the latest ASE/EACVI guidelines the same day of the RHC. Strain analysis was carried out by speckle-tracking echocardiography (QLAB 10.7, Philips). Clinical events during the follow-up were: acute heart failure hospitalization, cardiac transplant and all-cause mortality. Results Mean age was 59±12, 43.4% were women and 49 patients (64.5%) belonged to group 2 of PH. The median follow-up was 288 (ICR 92–534) days. Total number of events was 42 (55.3%, 9 deaths). Variables associated to events are shown in Table 1. All classic LV and RV systolic function and strain parameters were associated with a worse prognosis, being free-wall RV longitudinal strain (RVLS) the only one that remained as a prognostic factor in mutivariate analysis. Other variables associated with a worse prognosis were PCP>15 mmHg and NT-proBNP>1800, the latter being independent predictor of events. The attached figure shows event-free survival curves for the global population divided according to whether or not they belong to group II PH. Conclusions Our data highlight the prognostic value of free-wall RVLS and NT-proBNP in patients with established PH. NT-ProBNP was only useful in group II PH while free-wall RVLS identified patients with a higher risk of events in both groups, mainly in patients with heart disease Free event survival Curves Funding Acknowledgement Type of funding source: None
Published: 2020

122. Evaluation of left ventricular diastolic function in Marfan syndrome using speckle-tracking echocardiography

Author: A. Forteza Gil, A Borrego Hernandez, S. Mingo Santos, V Monivas Palomero, J. Segovia Cubero, C.E. Martin Lopez, J. Gonzalez Mirelis, S Moreno Casado, E Garcia-Izquierdo Jaen, M. A. Cavero Gibanel, C. Mitroi, S Navarro Rico, X Cia Mendioroz, and M Torres Sanabria
Subjects: Marfan syndrome, medicine.medical_specialty, Ejection fraction, business.industry, Diastole, Cardiomyopathy, Speckle tracking echocardiography, medicine.disease, Blood pressure, Tricuspid Valve Insufficiency, Internal medicine, medicine, Cardiology, Cardiovascular Surgical Procedure, Cardiology and Cardiovascular Medicine, business
Abstract: Background/Introduction Previous studies using conventional echocardiographic measurements have reported subclinical left diastolic dysfunction in patients with Marfan syndrome (MFS). Certain speckle-tracking echocardiography (STE) derived parameters have shown good correlation with invasive measurements of LV relaxation. Purpose To evaluate diastolic function in Marfan patients using STE-derived parameters along with traditional diastolic measurements and compare them with healthy controls. Methods We consecutively included 127 MFS patients with normal LV ejection fraction and no previous cardiovascular surgery or significant valvular regurgitation. We also studied 38 healthy controls (age and sex-matched). We performed LV and LA strain analysis using 2D STE (QLAB 10, Philips). Echocardiographic parameters recommended to assess diastolic function (according to ASE/EACVI 2016 guidelines) were also considered. Results Reported use of BB/ARB was 28/39% in MFS patients. According to current guidelines, all participants had normal diastolic function. MFS patients showed lower TDI e' velocities (septal and lateral) and higher average E/e' ratio compared to controls, but still within normal range. Regarding STE-derived measurements, LVGLS, EDLSR and PALS were significantly reduced in MFS. E/EDLSR ratio was higher among MFS patients, reflecting impaired LV relaxation. Interestingly, E/LVGLS was not different between both groups. Conclusion STE-derived parameters showed impaired LV relaxation in MFS patients compared to controls. Our results suggest that STE derived parameters can be markers of early diastolic dysfunction and provide a better insight into Marfan-related cardiomyopathy. STE derived parameters Funding Acknowledgement Type of funding source: Public Institution(s). Main funding source(s): Programa de Actividades de I+D de la Comunidad de Madrid
Published: 2020

123. Personalidad y agotamiento emocional académico en estudiantes universitarios peruanos: un estudio predictivo

Author: Rony Prada-Chapoñan, Jhonatan S. Navarro-Loli, and Sergio Alexis Dominguez-Lara
Subjects: Academic emotional exhaustion, LC8-6691, Mechanical Engineering, media_common.quotation_subject, Metals and Alloys, agotamiento emocional académico, Estudiantes universitarios, Special aspects of education, Education, Agotamiento emocional académico, Mechanics of Materials, Personalidade, personalidad, Personality, Estudantes universitários, estudiantes universitarios, Personalidad, College students, Psychology, Emotional exhaustion, Clinical psychology, media_common, Exaustão emocional acadêmica
Abstract: Resumen La personalidad es una característica relevante para predecir la conducta académica del estudiante, y su asociación con el agotamiento emocional académico aún es un tópico reciente. El propósito de la presente investigación fue analizar la capacidad predictiva de los cinco grandes factores de personalidad sobre el agotamiento emocional académico en universitarios, en una muestra de 453 estudiantes (60.9% mujeres) entre 17 y 40 años de edad, quienes fueron evaluados con la Escala de Cansancio Emocional y el Big Five Inventory-15p. Fue implementado un análisis de regresión múltiple para agotamiento emocional académico con los rasgos de personalidad como predictores. Los resultados indican que los rasgos de personalidad explican significativamente el agotamiento emocional (R2 > .20), y el neuroticismo, extraversión y responsabilidad predicen el agotamiento emocional académico. En conclusión, la capacidad predictiva de los rasgos de personalidad sobre el agotamiento emocional académico es significativa. Se discuten las consecuencias prácticas y las limitaciones del estudio. Abstract Personality is a relevant feature to predict the student’s academic behavior, and its association with academic emotional exhaustion is still a recent topic. The aim was determine the predictive ability of personality on academic emotional exhaustion in 453 college students (60.9% women) between ages 17 and 40 years old, who were assessed with the Emotional Exhaustion Scale and the Big Five Inventory-15p. Was implemented a regression multiple analysis on emotional exhaustion, with the personality traits as predictors. The findings shows that the personality traits explain significantly the emotional exhaustion (R2> .20), and the neuroticism, extraversion and consciousness predict the emotional exhaustion. In conclusion, the predictive ability of personality on academic emotional exhaustion is significant. The practical consequences and limitations are discussed. Resumo A personalidade é uma característica relevante para prever o comportamento acadêmico do aluno, e sua associação com a exaustão emocional acadêmica ainda é um tópico recente. O objetivo da presente investigação foi analisar a capacidade preditiva dos cinco fatores de personalidade na exaustão emocional acadêmica de universitários em uma amostra de 453 estudantes (60,9% mulheres) entre 17 e 40 anos, avaliados com a Escala de Exaustão Emocional e o Big Five Inventory-15p. Uma análise de regressão múltipla para exaustão emocional acadêmica foi implementada, com traços de personalidade como preditores. Os resultados indicam que os traços de personalidade explicam significativamente a exaustão emocional (R2 > .20), e o neuroticismo, a extroversão e a responsabilidade predizem a exaustão emocional acadêmica. Concluindo, a capacidade preditiva dos traços de personalidade no esgotamento emocional acadêmico é significativa. As conseqüências práticas e limitações do estudo são discutidas.
Published: 2020

124. Prevalence and risk factors associated with mental health disorders among medical students

Author: Alberto S. Navarro, María F. Macías, Eduardo Sánchez, José M. Zepeda, Felix Osuna, and Miriam C. Pérez
Subjects: education
Abstract: The mental health care of medical students is a complex process influenced by various innate or personal characteristics of the student, stressors related to medical training, social, economic, demographic and many other factors. Therefore, it is important to identify both the prevalence and the main risk factors that can trigger mental disorders in medical students, such as stress, burnout, anxiety, depression, suicidal ideation, suicide, among others. Specifically in these students, the prevalence of depression ranges between 2.9% and 38.2% respectively; likewise, exhaustion ("burnout") prevails in 28-45% of them. Most students do not seek the necessary support to solve such problems, which leads to serious consequences, such as the abuse of substances harmful to health, in addition to environments, situations or actions that lead to mental destabilization. The following paper is a review that emphasizes the prevalence and risk factors that can trigger these mental disorders, in order to make an early detection and timely intervention, such as attending psychiatric therapy and/or receiving support from the educational system itself.
Published: 2022

125. Thermodynamics and Kinetic Modeling of the ZnSO4·H2O Thermal Decomposition in the Presence of a Pd/Al2O3 Catalyst

Author: Gabriela V. T. Kurban, Artur S. C. Rego, Nathalli M. Mello, Eduardo A. Brocchi, Rogério C. S. Navarro, and Rodrigo F. M. Souza
Subjects: thermal decomposition kinetics, Technology, Control and Optimization, Pd catalyst, Renewable Energy, Sustainability and the Environment, Energy Engineering and Power Technology, zinc sulfate, Electrical and Electronic Engineering, Engineering (miscellaneous), Energy (miscellaneous)
Abstract: The sulfur–iodine thermochemical water-splitting cycle is a promising route proposed for hydrogen production. The decomposition temperature remains a challenge in the process. Catalysts, such as Pd supported on Al2O3, are being considered to decrease reaction temperatures. However, little is known regarding the kinetic behavior of such systems. In this work, zinc sulfate thermal decomposition was studied through non-isothermal thermogravimetric analysis to understand the effect of a catalyst within the sulfur–iodine reaction system context. The findings of this analysis were also related to a thermodynamic assessment. It was observed that the presence of Pd/Al2O3 modified the reaction mechanism, possibly with some intermediate reactions that were suppressed or remarkably accelerated. The proposed model suggests that zinc sulfate transformation occurred in two sequential stages without the Pd-based material. Activation energy values of 238 and 368 kJ·mol−1 were calculated. In the presence of Pd/Al2O3, an activation energy value of 204 kJ·mol−1 was calculated, which is lower than observed previously.
Published: 2022

126. Static detection of uncoalesced accesses in GPU programs

Author: Alur, Rajeev, primary, Devietti, Joseph, additional, Leija, Omar S. Navarro, additional, and Singhania, Nimit, additional
Published: 2021
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127. Effect of flaxseed (

Author: Carolina, Giraldo Pineda, Diego K, Yamul, and Alba S, Navarro
Subjects: Original Article
Abstract: Flaxseed (Linum usitatissimum L.) and yerba mate (Ilex paraguariensis) are particularly interesting as functional ingredients due to their high content of essential omega 3-fatty acids and antioxidant properties, respectively. The objective of this work was to formulate a corn snack enriched with flaxseed flour and yerba mate extract and evaluate its physicochemical and sensory properties. Flaxseed flour, added at three levels 1, 3 and 5%, increased the water activity, moisture content and cohesiveness, and decreased the hardness and plastic deformation of the samples. The flour also changed the superficial colour and made the microstructure more compact. On the contrary, yerba mate extract (1 and 3%) decreased the water activity, moisture content and cohesiveness, counteracting the effect of flaxseed flour. Yerba mate increased the plastic deformation and the antioxidant activity of the snacks. The colour was not modified and the microstructure was more fragmented in the presence of yerba mate. Sensory evaluation suggested that flaxseed flour and yerba mate affected the flavour but did not modify the colour and crunchiness of the product.
Published: 2020

128. Event Horizon Telescope imaging of the archetypal blazar 3C 279 at an extreme 20 microarcsecond resolution

Author: Robert Freund, N. W. Halverson, Benjamin R. Ryan, Paul Shaw, André Young, Andreas Eckart, A. Montaña, Michael Titus, Chen Yu Yu, Gertie Geertsema, Gao Feng, Ronald Grosslein, Ranjani Srinivasan, David Ball, Pablo Torne, Roberto Garcia, Hiroki Okino, Kotaro Moriyama, Chris Eckert, Lupin C.C. Lin, Geoffrey B. Crew, Vernon Fath, Freek Roelofs, David Sánchez-Arguelles, Luciano Rezzolla, Makoto Inoue, Michael Bremer, Jongsoo Kim, James Hoge, Michael Janssen, David M. Gale, Mel Rose, Jason Dexter, Do-Young Byun, J. G. A. Wouterloot, Rubén Herrero-Illana, Daniel C. M. Palumbo, Ta Shun Wei, Ching Tang Liu, Bradford Benson, Jadyn Anczarski, Patrick M. Koch, Ken Young, Jae-Young Kim, Minfeng Gu, Mislav Baloković, Mariafelicia De Laurentis, Laurent Loinard, A. Jiménez-Rosales, Tomohisa Kawashima, Nicolas Pradel, Heino Falcke, Olivier Gentaz, Dirk Muders, Shami Chatterjee, Britton Jeter, Rocco Lico, Craig Walther, David J. James, Homin Jiang, Michael H. Hecht, Gopal Narayanan, Qingwen Wu, Pierre Martin-Cocher, Michael A. Nowak, Alexander W. Raymond, Gregory Desvignes, Anne Kathrin Baczko, Chet Ruszczyk, Yutaka Hasegawa, Chao-Te Li, M. C. H. Wright, Andrew Nadolski, Alan P. Marscher, Christopher Beaudoin, Harriet Parsons, Peñalver Juan, Karl M. Menten, Silke Britzen, Frédéric Gueth, Shu Hao Chang, Andrew Chael, Daryl Haggard, Rodrigo Córdova Rosado, Ru-Sen Lu, Mansour Karami, José L. Gómez, Sang-Sung Lee, Tirupati K. Sridharan, Karl Friedrich Schuster, Ronald Hesper, Richard L. Plambeck, Iain Coulson, Jason SooHoo, Aristeidis Noutsos, Svetlana G. Jorstad, Li Ming Lu, James M. Cordes, David H. Hughes, Jonathan Weintroub, Chih-Wei Locutus Huang, Katherine L. Bouman, Roger J. Cappallo, Lijing Shao, Christiaan D. Brinkerink, John Kuroda, Ramesh Karuppusamy, Iniyan Natarajan, Jessica Dempsey, George Nystrom, John E. Carlstrom, Sera Markoff, Mark Kettenis, Neal R. Erickson, Jason W. Henning, R. Laing, Huang Lei, Kevin A. Dudevoir, Ilje Cho, William Stahm, Juan-Carlos Algaba, Junhan Kim, Hotaka Shiokawa, Martin P. McColl, James M. Moran, Chi-kwan Chan, Timothy C. Chuter, Thomas W. Folkers, Yi Chen, Christopher Greer, Lia Medeiros, C. Y. Kuo, Kuo Chang Han, Shoko Koyama, William Snow, Rurik A. Primiani, Sjoerd T. Timmer, F. Peter Schloerb, Stephen R. McWhirter, Fumie Tazaki, Norbert Wex, Ming-Tang Chen, Nimesh A. Patel, Aaron Faber, Mark Derome, Kazunori Akiyama, W. B. Everett, Hiroshi Nagai, Andrei Lobanov, Ignacio Ruiz, Pierre Christian, N. Phillips, David C. Forbes, Don Sousa, Michael Lindqvist, Christopher Risacher, Wen Ping Lo, Geoffrey C. Bower, Bart Ripperda, Dominique Broguiere, Maciek Wielgus, Antony A. Stark, Raquel Fraga-Encinas, Hiroaki Nishioka, Philippe Raffin, Hugo Messias, Feryal Özel, Jun Yi Koay, Buell T. Jannuzi, Sandra Bustamente, Roberto Neri, Jinchi Hao, Ye-Fei Yuan, Garrett K. Keating, Lynn D. Matthews, Avery E. Broderick, Mark G. Rawlings, Ciriaco Goddi, Tod R. Lauer, Kamal Souccar, Alan L. Roy, S. Navarro, Luis C. Ho, Timothy Norton, Roger Brissenden, Doosoo Yoon, Jongho Park, Richard Lacasse, Paul T. P. Ho, Derek Ward-Thompson, Atish Kamble, Akihiko Hirota, S. Sánchez, D. A. Graham, Vincent Piétu, Kyle D. Massingill, M. Zeballos, Mahito Sasada, Hideo Ogawa, Ziri Younsi, Chih Cheng Chang, Alejandro F. Sáez-Madain, Christian M. Fromm, Ramesh Narayan, Shuichiro Tsuda, Ryan Berthold, Gibwa Musoke, Laura Vertatschitsch, Masanori Nakamura, Remo P. J. Tilanus, Cornelia Müller, Kimihiro Kimura, Roman Gold, Venkatessh Ramakrishnan, Yuzhu Cui, Frederick K. Baganoff, Alan R. Whitney, Aleksandar Popstefanija, Helge Rottmann, Yuan Feng, Ralph Eatough, Tuomas Savolainen, Neil M. Nagar, Alexander Allardi, M. Mora-Klein, Thomas Bronzwaer, Mark Gurwell, Bong Won Sohn, Ivan Marti-Vidal, Chih Chiang Han, Hung Yi Pu, Yan-Rong Li, Shan Shan Zhao, Song Chu Chang, Zhi-Qiang Shen, John F. C. Wardle, Carsten Kramer, Koushik Chatterjee, Wagner Jan, Tomoaki Oyama, Ray Blundell, Motoki Kino, Alan E. E. Rogers, Rebecca Azulay, Jordy Davelaar, Tyler Trent, Satoki Matsushita, Kazi L.J. Rygl, Shuo Zhang, John E. Barrett, Peter Oshiro, Ryan Chilson, Jorge A. Preciado-López, Daniel Michalik, Peter Galison, Uwe Bach, Ilse van Bemmel, Pim Schellart, Michael D. Johnson, Jiang Wu, J. Anton Zensus, S. A. Dzib, Arturo I. Gómez-Ruiz, Meyer Zhao Zheng, David John, Dimitrios Psaltis, Daniel P. Marrone, M. Poirier, Shiro Ikeda, Ralph G. Marson, A. Hernandez-Gomez, Sven Dornbusch, George Reiland, Mareki Honma, J. Blanchard, Ed Fomalont, Taehyun Jung, Izumi Mizuno, Monika Moscibrodzka, Vincent L. Fish, Matthew R. Dexter, Paul Tiede, Rodrigo Amestica, Nicholas R. MacDonald, Gisela N. Ortiz-León, Colin J. Lonsdale, Callie Matulonis, Charles F. Gammie, Per Friberg, Boris Georgiev, W. Boland, Ramprasad Rao, Guang-Yao Zhao, Joseph R. Farah, Zhiyuan Li, Hector Olivares, Sara Issaoun, Elisabetta Liuzzo, C. M. Violette Impellizzeri, Michael Kramer, Oliver Porth, Thomas P. Krichbaum, Dominic W. Pesce, Daniel R. van Rossum, David R. Smith, Robert Wharton, Kuan Yu Liu, David P. Woody, Arash Roshanineshat, Sheperd S. Doeleman, Chung Chen Chen, Ziyan Zhu, Ue-Li Pen, Yosuke Mizuno, Prather Ben, Sascha Trippe, Walter Alef, Liu Kuo, Alexandra S. Rahlin, William Montgomerie, George N. Wong, Jirong Mao, Kazuhiro Hada, Efthalia Traianou, John Conway, Remi Sassella, Eduardo Ros, Kevin M. Silva, Derek Kubo, E. Castillo-Domínguez, Huib Jan van Langevelde, Keiichi Asada, Des Small, Joseph Neilsen, Chi H. Nguyen, Chunchong Ni, Yusuke Kono, Ryan Keisler, Paul Yamaguchi, Lindy Blackburn, Erik M. Leitch, Roger Deane, Lucy M. Ziurys, K. T. Story, Joseph Crowley, Nathan Whitehorn, Stefan Heyminck, Kenji Toma, Antxon Alberdi, Yau De Huang, Dan Bintley, Y Kim, J., Krichbaum, T. P., Broderick, A. E., Wielgus, M., Blackburn, L., Gomez, J. -L., Johnson, M. D., Bouman, K. L., Chael, A., Akiyama, K., Jorstad, S., Marscher, A. P., Issaoun, S., Janssen, M., Chan, C. -K., Savolainen, T., Pesce, D. W., Ozel, F., De Laurentis, M., Deane, R., Institut de RadioAstronomie Millimétrique (IRAM), Centre National de la Recherche Scientifique (CNRS), Laboratoire d'études spatiales et d'instrumentation en astrophysique (LESIA (UMR_8109)), Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Instituto de RadioAstronomía Milimétrica (IRAM), Event Horizon Telescope, Ministerio de Economía y Competitividad (España), European Commission, National Aeronautics and Space Administration (US), Max Planck Institute for Radio Astronomy, Perimeter Institute for Theoretical Physics, Harvard University, CSIC, Princeton University, Boston University, Radboud University Nijmegen, University of Arizona, Anne Lähteenmäki Group, Academia Sinica - Institute of Astronomy and Astrophysics, Massachusetts Institute of Technology, East Asian Observatory, Nederlandse Onderzoekschool voor Astronomie, Academia Sinica, Institut de Radio Astronomie Millimétrique, Korea Astronomy and Space Science Institute, University of Chicago, Cornell University, University of Amsterdam, CAS - Shanghai Astronomical Observatory, Chalmers University of Technology, National Astronomical Observatory of Japan, University of Naples Federico II, University of Pretoria, University of Colorado Boulder, National Radio Astronomy Observatory, Goethe University Frankfurt, University of Illinois at Urbana-Champaign, University of Waterloo, Instituto Nacional de Astrofisica Optica y Electronica, University of Groningen, Peking University, Max Planck Institute for Extraterrestrial Physics, Joint Institute for VLBI in Europe, California Institute of Technology, National Sun Yat-sen University, National Optical Astronomy Observatory, CAS - Institute of High Energy Physics, Nanjing University, INAF Istituto di Radioastronomia, Instituto de Radioastronomía y Astrofísica, CAS - National Astronomical Observatories, Universidad de Valencia, Universidad de Concepción, University of Massachusetts, Rhodes University, University of California Berkeley, Los Alamos National Laboratory, IRAM, Tohoku University, Seoul National University, Brandeis University, University of Central Lancashire, Huazhong University of Science and Technology, University of Science and Technology of China, University of Vermont, Villanova University, United States Department of Energy, Western University, Royal Netherlands Meteorological Institute, McGill University, Osaka Prefecture University, European Southern Observatory Santiago, University of Manchester, National Radio Astronomy Observatory Socorro, Rochester Institute of Technology, Washington University St. Louis, Systems and Technology Research, Georgia Institute of Technology, Stanford University, University of California Los Angeles, Department of Electronics and Nanoengineering, Aalto-yliopisto, Aalto University, Astronomy, High Energy Astrophys. & Astropart. Phys (API, FNWI), and Gravitation and Astroparticle Physics Amsterdam
Subjects: ACTIVE GALACTIC NUCLEI, Brightness, Active galactic nucleus, active [Galaxies], Astrophysics::High Energy Astrophysical Phenomena, Astronomy, galaxies: active, Astrophysics, Astrophysics::Cosmology and Extragalactic Astrophysics, 01 natural sciences, Submillimeter Array, FLOWS, SCALE CIRCULAR-POLARIZATION, 0103 physical sciences, Very-long-baseline interferometry, Blazar, 010303 astronomy & astrophysics, Astrophysics::Galaxy Astrophysics, Physics, Event Horizon Telescope, [PHYS]Physics [physics], Jet (fluid), 010308 nuclear & particles physics, Astronomy and Astrophysics, FLARE, galaxies: jets, individual: 3C 279 [Galaxies], LONG, VARIABILITY, galaxies: individual: 3C 279, GAMMA-RAY, QUASARS, 13. Climate action, Space and Planetary Science, techniques: interferometric, Brightness temperature, ACCRETION DISKS, interferometric [Techniques], jets [Galaxies], RELATIVISTIC JETS, [PHYS.ASTR]Physics [physics]/Astrophysics [astro-ph]
Abstract: Open Access article, published by EDP Sciences, under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Open Access funding provided by Max Planck Society.--All authors: Kim, Jae-Young; Krichbaum, Thomas P.; Broderick, Avery E.; Wielgus, Maciek; Blackburn, Lindy; Gómez, José L.; Johnson, Michael D.; Bouman, Katherine L.; Chael, Andrew; Akiyama, Kazunori; Jorstad, Svetlana; Marscher, Alan P.; Issaoun, Sara; Janssen, Michael; Chan, Chi-kwan; Savolainen, Tuomas; Pesce, Dominic W.; Özel, Feryal; Alberdi, Antxon; Alef, Walter Asada, Keiichi; Azulay, Rebecca; Baczko, Anne-Kathrin; Ball, David; Baloković, Mislav; Barrett, John; Bintley, Dan; Boland, Wilfred; Bower, Geoffrey C.; Bremer, Michael; Brinkerink, Christiaan D.; Brissenden, Roger; Britzen, Silke; Broguiere, Dominique; Bronzwaer, Thomas; Byun, Do-Young; Carlstrom, John E.; Chatterjee, Shami; Chatterjee, Koushik; Chen, Ming-Tang; Chen, Yongjun; Cho, Ilje; Christian, Pierre; Conway, John E.; Cordes, James M.; Crew, Geoffrey B.; Cui, Yuzhu; Davelaar, Jordy; De Laurentis, Mariafelicia; Deane, Roger; Dempsey, Jessica; Desvignes, Gregory; Dexter, Jason; Doeleman, Sheperd S.; Eatough, Ralph P.; Falcke, Heino; Fish, Vincent L.; Fomalont, Ed; Fraga-Encinas, Raquel; Friberg, Per; Fromm, Christian M.; Galison, Peter; Gammie, Charles F.; García, Roberto; Gentaz, Olivier; Georgiev, Boris; Goddi, Ciriaco; Gold, Roman; Gómez-Ruiz, Arturo I.; Gu, Minfeng; Gurwell, Mark; Hada, Kazuhiro; Hecht, Michael H.; Hesper, Ronald; Ho, Luis C.; Ho, Paul; Honma, Mareki; Huang, Chih-Wei L.; Huang, Lei; Hughes, David H.; Ikeda, Shiro; Inoue, Makoto; James, David J.; Jannuzi, Buell T.; Jeter, Britton; Jiang, Wu; Jimenez-Rosales, Alejandra; Jung, Taehyun; Karami, Mansour; Karuppusamy, Ramesh; Kawashima, Tomohisa; Keating, Garrett K.; Kettenis, Mark; Kim, Junhan; Kim, Jongsoo; Kino, Motoki; Koay, Jun Yi; Koch, Patrick M.; Koyama, Shoko; Kramer, Michael; Kramer, Carsten; Kuo, Cheng-Yu; Lauer, Tod R.; Lee, Sang-Sung; Li, Yan-Rong; Li, Zhiyuan; Lindqvist, Michael; Lico, Rocco; Liu, Kuo; Liuzzo, Elisabetta; Lo, Wen-Ping; Lobanov, Andrei P.; Loinard, Laurent; Lonsdale, Colin; Lu, Ru-Sen; MacDonald, Nicholas R.; Mao, Jirong; Markoff, Sera; Marrone, Daniel P.; Martí-Vidal, Iván; Matsushita, Satoki; Matthews, Lynn D.; Medeiros, Lia; Menten, Karl M.; Mizuno, Yosuke; Mizuno, Izumi; Moran, James M.; Moriyama, Kotaro; Moscibrodzka, Monika; Musoke, Gibwa; Müller, Cornelia; Nagai, Hiroshi; Nagar, Neil M.; Nakamura, Masanori; Narayan, Ramesh; Narayanan, Gopal; Natarajan, Iniyan; Neri, Roberto; Ni, Chunchong; Noutsos, Aristeidis; Okino, Hiroki; Olivares, Héctor; Ortiz-León, Gisela N.; Oyama, Tomoaki; Palumbo, Daniel C. M.; Park, Jongho; Patel, Nimesh; Pen, Ue-Li; Piétu, Vincent; Plambeck, Richard; PopStefanija, Aleksandar; Porth, Oliver; Prather, Ben; Preciado-López, Jorge A.; Psaltis, Dimitrios; Pu, Hung-Yi; Ramakrishnan, Venkatessh; Rao, Ramprasad; Rawlings, Mark G.; Raymond, Alexander W.; Rezzolla, Luciano; Ripperda, Bart; Roelofs, Freek; Rogers, Alan; Ros, Eduardo; Rose, Mel; Roshanineshat, Arash; Rottmann, Helge; Roy, Alan L.; Ruszczyk, Chet; Ryan, Benjamin R.; Rygl, Kazi L. J.; Sánchez, Salvador; Sánchez-Arguelles, David; Sasada, Mahito; Schloerb, F. Peter; Schuster, Karl-Friedrich; Shao, Lijing; Shen, Zhiqiang; Small, Des; Sohn, Bong Won; SooHoo, Jason; Tazaki, Fumie; Tiede, Paul; Tilanus, Remo P. J.; Titus, Michael; Toma, Kenji; Torne, Pablo; Trent, Tyler; Traianou, Efthalia; Trippe, Sascha; Tsuda, Shuichiro; van Bemmel, Ilse; van Langevelde, Huib Jan; van Rossum, Daniel R.; Wagner, Jan; Wardle, John; Ward-Thompson, Derek; Weintroub, Jonathan; Wex, Norbert; Wharton, Robert; Wong, George N.; Wu, Qingwen; Yoon, Doosoo; Young, André; Young, Ken; Younsi, Ziri; Yuan, Feng; Yuan, Ye-Fei; Zensus, J. Anton; Zhao, Guangyao; Zhao, Shan-Shan; Zhu, Ziyan; Algaba, Juan-Carlos; Allardi, Alexander; Amestica, Rodrigo; Anczarski, Jadyn; Bach, Uwe; Baganoff, Frederick K.; Beaudoin, Christopher; Benson, Bradford A.; Berthold, Ryan; Blanchard, Jay M.; Blundell, Ray; Bustamente, Sandra; Cappallo, Roger; Castillo-Domínguez, Edgar; Chang, Chih-Cheng; Chang, Shu-Hao; Chang, Song-Chu; Chen, Chung-Chen; Chilson, Ryan; Chuter, Tim C.; Rosado, Rodrigo Córdova; Coulson, Iain M.; Crowley, Joseph; Derome, Mark; Dexter, Matthew; Dornbusch, Sven; Dudevoir, Kevin A.; Dzib, Sergio A.; Eckart, Andreas; Eckert, Chris; Erickson, Neal R.; Everett, Wendeline B.; Faber, Aaron; Farah, Joseph R.; Fath, Vernon; Folkers, Thomas W.; Forbes, David C.; Freund, Robert; Gale, David M.; Gao, Feng; Geertsema, Gertie; Graham, David A.; Greer, Christopher H.; Grosslein, Ronald; Gueth, Frédéric; Haggard, Daryl; Halverson, Nils W.; Han, Chih-Chiang; Han, Kuo-Chang; Hao, Jinchi; Hasegawa, Yutaka; Henning, Jason W.; Hernández-Gómez, Antonio; Herrero-Illana, Rubén; Heyminck, Stefan; Hirota, Akihiko; Hoge, James; Huang, Yau-De; Violette Impellizzeri, C. M.; Jiang, Homin; John, David; Kamble, Atish; Keisler, Ryan; Kimura, Kimihiro; Kono, Yusuke; Kubo, Derek; Kuroda, John; Lacasse, Richard; Laing, Robert A.; Leitch, Erik M.; Li, Chao-Te; Lin, Lupin C. -C.; Liu, Ching-Tang; Liu, Kuan-Yu; Lu, Li-Ming; Marson, Ralph G.; Martin-Cocher, Pierre L.; Massingill, Kyle D.; Matulonis, Callie; McColl, Martin P.; McWhirter, Stephen R.; Messias, Hugo; Meyer-Zhao, Zheng; Michalik, Daniel; Montaña, Alfredo; Montgomerie, William; Mora-Klein, Matias; Muders, Dirk; Nadolski, Andrew; Navarro, Santiago; Neilsen, Joseph; Nguyen, Chi H.; Nishioka, Hiroaki; Norton, Timothy; Nowak, Michael A.; Nystrom, George; Ogawa, Hideo; Oshiro, Peter; Oyama, Tomoaki; Parsons, Harriet; Peñalver, Juan; Phillips, Neil M.; Poirier, Michael; Pradel, Nicolas; Primiani, Rurik A.; Raffin, Philippe A.; Rahlin, Alexandra S.; Reiland, George; Risacher, Christopher; Ruiz, Ignacio; Sáez-Madaín, Alejandro F.; Sassella, Remi; Schellart, Pim; Shaw, Paul; Silva, Kevin M.; Shiokawa, Hotaka; Smith, David R.; Snow, William; Souccar, Kamal; Sousa, Don; Sridharan, Tirupati K.; Srinivasan, Ranjani; Stahm, William; Stark, Antony A.; Story, Kyle; Timmer, Sjoerd T.; Vertatschitsch, Laura; Walther, Craig; Wei, Ta-Shun; Whitehorn, Nathan; Whitney, Alan R.; Woody, David P.; Wouterloot, Jan G. A.; Wright, Melvin; Yamaguchi, Paul; Yu, Chen-Yu; Zeballos, Milagros; Zhang, Shuo; Ziurys, Lucy; Event Horizon Telescope Collaboration, 3C 279 is an archetypal blazar with a prominent radio jet that show broadband flux density variability across the entire electromagnetic spectrum. We use an ultra-high angular resolution technique - global Very Long Baseline Interferometry (VLBI) at 1.3mm (230 GHz) - to resolve the innermost jet of 3C 279 in order to study its fine-scale morphology close to the jet base where highly variable-ray emission is thought to originate, according to various models. The source was observed during four days in April 2017 with the Event Horizon Telescope at 230 GHz, including the phased Atacama Large Millimeter/submillimeter Array, at an angular resolution of ∼20 μas (at a redshift of z = 0:536 this corresponds to ∼0:13 pc ∼ 1700 Schwarzschild radii with a black hole mass MBH = 8 × 108 M⊙). Imaging and model-fitting techniques were applied to the data to parameterize the fine-scale source structure and its variation.We find a multicomponent inner jet morphology with the northernmost component elongated perpendicular to the direction of the jet, as imaged at longer wavelengths. The elongated nuclear structure is consistent on all four observing days and across diffierent imaging methods and model-fitting techniques, and therefore appears robust. Owing to its compactness and brightness, we associate the northern nuclear structure as the VLBI "core". This morphology can be interpreted as either a broad resolved jet base or a spatially bent jet.We also find significant day-to-day variations in the closure phases, which appear most pronounced on the triangles with the longest baselines. Our analysis shows that this variation is related to a systematic change of the source structure. Two inner jet components move non-radially at apparent speeds of ∼15 c and ∼20 c (∼1:3 and ∼1:7 μas day-1, respectively), which more strongly supports the scenario of traveling shocks or instabilities in a bent, possibly rotating jet. The observed apparent speeds are also coincident with the 3C 279 large-scale jet kinematics observed at longer (cm) wavelengths, suggesting no significant jet acceleration between the 1.3mm core and the outer jet. The intrinsic brightness temperature of the jet components are ≤1010 K, a magnitude or more lower than typical values seen at ≥7mm wavelengths. The low brightness temperature and morphological complexity suggest that the core region of 3C 279 becomes optically thin at short (mm) wavelengths. © J.-Y. Kim et al. 2020., The authors of the present paper thank the following organizations and programs: the Academy of Finland (projects 274477, 284495, 312496); the Advanced European Network of E-infrastructures for Astronomy with the SKA (AENEAS) project, supported by the European Commission Framework Programme Horizon 2020 Research and Innovation action under grant agreement 731016; the Alexander von Humboldt Stiftung; the Black Hole Initiative at Harvard University, through a grant (60477) from the John Templeton Foundation; the China Scholarship Council; Comision Nacional de Investigacion Cientifica y Tecnologica (CONICYT, Chile, via PIA ACT172033, Fondecyt projects 1171506 and 3190878, BASAL AFB-170002, ALMA-conicyt 31140007); Consejo Nacional de Ciencia y Tecnologia (CONACYT, Mexico, projects 104497, 275201, 279006, 281692); the Delaney Family via the Delaney Family John A. Wheeler Chair at Perimeter Institute; Direccion General de Asuntos del Personal Academico -Universidad Nacional Autonoma de Mexico (DGAPA -UNAM, project IN112417); the European Research Council Synergy Grant "BlackHoleCam: Imaging the Event Horizon of Black Holes" (grant 610058); the Generalitat Valenciana postdoctoral grant APOSTD/2018/177 and GenT Program (project CIDEGENT/2018/021); the Gordon and Betty Moore Foundation (grants GBMF-3561, GBMF-5278); the Istituto Nazionale di Fisica Nucleare (INFN) sezione di Napoli, iniziative specifiche TEONGRAV; the International Max Planck Research School for Astronomy and Astrophysics at the Universities of Bonn and Cologne; the Jansky Fellowship program of the National Radio Astronomy Observatory (NRAO); the Japanese Government (Monbukagakusho: MEXT) Scholarship; the Japan Society for the Promotion of Science (JSPS) Grant-inAid for JSPS Research Fellowship (JP17J08829); the Key Research Program of Frontier Sciences, Chinese Academy of Sciences (CAS, grants QYZDJSSW-SLH057, QYZDJ-SSW-SYS008, ZDBS-LY-SLH011); the Leverhulme Trust Early Career Research Fellowship; the Malaysian Fundamental Research Grant Scheme (FRGS, grant FRGS/1/2019/STG02/UM/02/6); the Max-PlanckGesellschaft (MPG); the Max Planck Partner Group of the MPG and the CAS; the MEXT/JSPS KAKENHI (grants 18KK0090, JP18K13594, JP18K03656, JP18H03721, 18K03709, 18H01245, 25120007); the MIT International Science and Technology Initiatives (MISTI) Funds; the Ministry of Science and Technology (MOST) of Taiwan (105-2112-M-001-025-MY3, 106-2112-M-001-011, 106-2119-M-001-027, 107-2119-M-001-017, 107-2119-M-001-020, and 107-2119-M-110-005); the National Aeronautics and Space Administration (NASA, Fermi Guest Investigator grant 80NSSC17K0649 and Hubble Fellowship grant HST-HF2-51431.001-A awarded by the Space Telescope Science Institute, which is operated by the Association of Universities for Research in Astronomy, Inc. r , for NASA, under contract NAS5-26555); the National Institute of Natural Sciences (NINS) of Japan; the National Key Research and Development Program of China (grant 2016YFA0400704, 2016YFA0400702); the National Science Foundation (NSF, grants AST-0096454, AST-0352953, AST-0521233, AST-0705062, AST-0905844, AST-0922984, AST-1126433, AST-1140030, DGE-1144085, AST-1207704, AST-1207730, AST-1207752, MRI-1228509, OPP-1248097, AST-1310896, AST-1312651, AST-1337663, AST-1440254, AST-1555365, AST-1715061, AST-1615796, AST-1716327, OISE-1743747, AST-1816420); the Natural Science Foundation of China (grants 11573051, 11633006, 11650110427, 10625314, 11721303, 11725312, 11933007); the Natural Sciences and Engineering Research Council of Canada (NSERC, including a Discovery Grant and the NSERC Alexander Graham Bell Canada Graduate Scholarships-Doctoral Program); the National Youth Thousand Talents Program of China; the National Research Foundation of Korea (the Global PhD Fellowship Grant: grants NRF-2015H1A2A1033752, 2015-R1D1A1A01056807, the Korea Research Fellowship Program: NRF-2015H1D3A1066561); the Netherlands Organization for Scientific Research (NWO) VICI award (grant 639.043.513) and Spinoza Prize SPI 78-409; the New Scientific Frontiers with Precision Radio Interferometry Fellowship awarded by the South African Radio Astronomy Observatory (SARAO), which is a facility of the National Research Foundation (NRF), an agency of the Department of Science and Technology (DST) of South Africa; the Onsala Space Observatory (OSO) national infrastructure, for the provisioning of its facilities/observational support (OSO receives funding through the Swedish Research Council under grant 2017-00648) the Perimeter Institute for Theoretical Physics (research at Perimeter Institute is supported by the Government of Canada through the Department of Innovation, Science and Economic Development and by the Province of Ontario through the Ministry of Research, Innovation and Science); the Russian Science Foundation (grant 17-12-01029); the Spanish Ministerio de Economia y Competitividad (grants PGC2018-098915-B-C21, AYA201680889-P); the State Agency for Research of the Spanish MCIU through the "Center of Excellence Severo Ochoa" award for the Instituto de Astrofisica de Andalucia (SEV-2017-0709); the Toray Science Foundation; the US Department of Energy (USDOE) through the Los Alamos National Laboratory (operated by Triad National Security, LLC, for the National Nuclear Security Administration of the USDOE (Contract 89233218CNA000001)); the Italian Ministero dell'Istruzione Universita e Ricerca through the grant Progetti Premiali 2012-iALMA (CUP C52I13000140001); the European Union's Horizon 2020 research and innovation programme under grant agreement No 730562 RadioNet; ALMA North America Development Fund; the Academia Sinica; Chandra TM6-17006X; the GenT Program (Generalitat Valenciana) Project CIDEGENT/2018/021. This work used the Extreme Science and Engineering Discovery Environment (XSEDE), supported by NSF grant ACI-1548562, and CyVerse, supported by NSF grants DBI-0735191, DBI-1265383, and DBI1743442. XSEDE Stampede2 resource at TACC was allocated through TGAST170024 and TG-AST080026N. XSEDE JetStream resource at PTI and TACC was allocated through AST170028. The simulations were performed in part on the SuperMUC cluster at the LRZ in Garching, on the LOEWE cluster in CSC in Frankfurt, and on the HazelHen cluster at the HLRS in Stuttgart. This research was enabled in part by support provided by Compute Ontario (http://computeontario. r ca), Calcul Quebec (http://www.calculquebec.ca) and Compute Canada (http://www.computecanada.ca).We thank the sta ff at the participating observatories, correlation centers, and institutions for their enthusiastic support. This paper makes use of the following ALMA data: ADS/JAO.ALMA#2016.1.01154.V, ADS/JAO.ALMA#2016.1.01176.V. ALMA is a partnership of the European Southern Observatory (ESO; Europe, representing its member states), NSF, and National Institutes of Natural Sciences of Japan, together with National Research Council (Canada), Ministry of Science and Technology (MOST; Taiwan), Academia Sinica Institute of Astronomy and Astrophysics (ASIAA; Taiwan), and Korea Astronomy and Space Science Institute (KASI; Republic of Korea), in cooperation with the Republic of Chile. The Joint ALMA Observatory is operated by ESO, Associated Universities, Inc. (AUI)/NRAO, and the National Astronomical Observatory of Japan (NAOJ). The NRAO is a facility of the NSF operated under cooperative agreement by AUI. APEX is a collaboration between the Max-Planck-Institut fur Radioastronomie (Germany), ESO, and the Onsala Space Observatory (Sweden). The SMA is a joint project between the SAO and ASIAA and is funded by the Smithsonian Institution and the Academia Sinica. The JCMT is operated by the East Asian Observatory on behalf of the NAOJ, ASIAA, and KASI, as well as the Ministry of Finance of China, Chinese Academy of Sciences, and the National Key R&D Program (No. 2017YFA0402700) of China. Additional funding support for the JCMT is provided by the Science and Technologies Facility Council (UK) and participating universities in the UK and Canada. The LMT is a project operated by the Instituto Nacional de Astrofisica, Optica, y Electronica (Mexico) and the University of Massachusetts at Amherst (USA). The IRAM 30-m telescope on Pico Veleta, Spain is operated by IRAM and supported by CNRS (Centre National de la Recherche Scientifique, France), MPG (Max-Planck-Gesellschaft, Germany) and IGN (Instituto Geografico Nacional, Spain). The SMT is operated by the Arizona Radio Observatory, a part of the Steward Observatory of the University of Arizona, with financial support of operations from the State of Arizona and financial support for instrumentation development from the NSF. The SPT is supported by the National Science Foundation through grant PLR1248097. Partial support is also provided by the NSF Physics Frontier Center grant PHY-1125897 to the Kavli Institute of Cosmological Physics at the University of Chicago, the Kavli Foundation and the Gordon and Betty Moore Foundation grant GBMF 947. The SPT hydrogen maser was provided on loan from the GLT, courtesy of ASIAA. The EHTC has received generous donations of FPGA chips from Xilinx Inc., under the Xilinx University Program. The EHTC has benefited from technology shared under open-source license by the Collaboration for Astronomy Signal Processing and Electronics Research (CASPER). The EHT project is grateful to T4Science and Microsemi for their assistance with Hydrogen Masers. This research has made use of NASA's Astrophysics Data System. We gratefully acknowledge the support provided by the extended sta ff of the ALMA, both from the inception of the ALMA Phasing Project through the observational campaigns of 2017 and 2018. We would like to thank A. Deller and W. Brisken for EHT-specific support with the use of DiFX. We acknowledge the significance that Maunakea, where the SMA and JCMT EHT stations are located, has for the indigenous Hawaiian people. r This research has made use of data obtained with the Global Millimeter VLBI Array (GMVA), which consists of telescopes operated by the MPIfR, IRAM, Onsala, Metsahovi, Yebes, the Korean VLBI Network, the Green Bank Observatory and the Very Long Baseline Array (VLBA). The VLBA is an instrument of the National Radio Astronomy Observatory. The National Radio Astronomy Observatory is a facility of the National Science Foundation operated by Associated Universities, Inc. The data were correlated at the correlator of the MPIfR in Bonn, Germany. This study makes use of 43 GHz VLBA data from the VLBA-BU Blazar Monitoring Program (VLBABU-BLAZAR; http://www.bu.edu/blazars/VLBAproject.html), funded by NASA through the Fermi Guest Investigator Program.
Published: 2020

129. Calibration and performance of the NIKA2 camera at the IRAM 30-m Telescope

Author: Shibo Shu, Peter A. R. Ade, A. Beelen, D. John, A. Andrianasolo, Florian Kéruzoré, Philip Daniel Mauskopf, Albrecht Sievers, L. Perotto, A. Catalano, F. Pierfederici, R. Zylka, Aurélien Benoit, Paulo J. V. Garcia, F. Mayet, A. Ritacco, V. Revéret, H. Roussel, Nicolas Ponthieu, R. Adam, J. Peñalver, S. Berta, C. Tucker, H. Aussel, O. Bourrion, Manuel Calvo, S. Navarro, J. F. Macías-Pérez, K. F. Schuster, E. F. C. Driessen, C. Romero, Pascale Andre, F.-X. Désert, Florian Ruppin, J.-F. Lestrade, G. Lagache, A. Bideaud, J. Goupy, Anaëlle Maury, Alessandro Monfardini, Bilal Ladjelate, B. Comis, Alicia Gomez, M. De Petris, Giampaolo Pisano, S. Leclercq, Simon Doyle, C. Kramer, Laboratoire de Physique Subatomique et de Cosmologie (LPSC), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes (UGA)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP ), Université Grenoble Alpes (UGA), Institut de Planétologie et d'Astrophysique de Grenoble (IPAG), Centre National d'Études Spatiales [Toulouse] (CNES)-Observatoire des Sciences de l'Univers de Grenoble (OSUG ), Institut national des sciences de l'Univers (INSU - CNRS)-Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry])-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Université Grenoble Alpes (UGA)-Météo-France -Institut national des sciences de l'Univers (INSU - CNRS)-Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry])-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Université Grenoble Alpes (UGA)-Météo-France, Laboratoire Leprince-Ringuet (LLR), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-École polytechnique (X)-Centre National de la Recherche Scientifique (CNRS), Cardiff University, Astrophysique Interprétation Modélisation (AIM (UMR_7158 / UMR_E_9005 / UM_112)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut national des sciences de l'Univers (INSU - CNRS)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Institut d'astrophysique spatiale (IAS), Université Paris-Sud - Paris 11 (UP11)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS)-Centre National d’Études Spatiales [Paris] (CNES), Hélium : du fondamental aux applications (NEEL - HELFA), Institut Néel (NEEL), Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes (UGA)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP ), Université Grenoble Alpes (UGA)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes (UGA)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP ), Institut de RadioAstronomie Millimétrique (IRAM), Centre National de la Recherche Scientifique (CNRS), Cryogénie (NEEL - Cryo), Università degli Studi di Roma 'La Sapienza' = Sapienza University [Rome] (UNIROMA), Universidad Católica del Norte [Antofagasta], Centro de Astrobiologia [Madrid] (CAB), Instituto Nacional de Técnica Aeroespacial (INTA)-Consejo Superior de Investigaciones Científicas [Madrid] (CSIC), Instituto de RadioAstronomía Milimétrica (IRAM), Laboratoire d'Astrophysique de Marseille (LAM), Aix Marseille Université (AMU)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National d'Études Spatiales [Toulouse] (CNES)-Centre National de la Recherche Scientifique (CNRS), Laboratoire d'Etude du Rayonnement et de la Matière en Astrophysique et Atmosphères = Laboratory for Studies of Radiation and Matter in Astrophysics and Atmospheres (LERMA), École normale supérieure - Paris (ENS-PSL), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-CY Cergy Paris Université (CY), Institut d'Astrophysique de Paris (IAP), Institut national des sciences de l'Univers (INSU - CNRS)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Institut national des sciences de l'Univers (INSU - CNRS)-Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry])-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Université Grenoble Alpes (UGA)-Institut national des sciences de l'Univers (INSU - CNRS)-Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry])-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Université Grenoble Alpes (UGA), Centre National de la Recherche Scientifique (CNRS)-École polytechnique (X)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut national des sciences de l'Univers (INSU - CNRS)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP), Université Paris-Sud - Paris 11 (UP11)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS), Hélium : du fondamental aux applications (HELFA), Cryogénie (Cryo), Laboratoire d'Etude du Rayonnement et de la Matière en Astrophysique (LERMA (UMR_8112)), Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-CY Cergy Paris Université (CY), Université Joseph Fourier - Grenoble 1 (UJF)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Institut Polytechnique de Grenoble - Grenoble Institute of Technology-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes (UGA), Centre National d'Études Spatiales [Toulouse] (CNES)-Université Grenoble Alpes (UGA)-Centre National de la Recherche Scientifique (CNRS)-Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire des Sciences de l'Univers de Grenoble (OSUG), Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry])-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP)-Institut national de recherche en sciences et technologies pour l'environnement et l'agriculture (IRSTEA)-Université Joseph Fourier - Grenoble 1 (UJF)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes (UGA)-Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry])-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP)-Institut national de recherche en sciences et technologies pour l'environnement et l'agriculture (IRSTEA)-Université Joseph Fourier - Grenoble 1 (UJF)-Centre National de la Recherche Scientifique (CNRS), Centre National de la Recherche Scientifique (CNRS)-Institut national des sciences de l'Univers (INSU - CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris Diderot - Paris 7 (UPD7), Université Grenoble Alpes (UGA)-Centre National de la Recherche Scientifique (CNRS)-Université Joseph Fourier - Grenoble 1 (UJF), Centre National de la Recherche Scientifique (CNRS)-Institut national des sciences de l'Univers (INSU - CNRS)-Aix Marseille Université (AMU)-Centre National d'Études Spatiales [Toulouse] (CNES), PSL Research University (PSL)-PSL Research University (PSL)-Université de Cergy Pontoise (UCP), Université Paris-Seine-Université Paris-Seine-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Unidad de Excelencia Científica María de Maeztu Centro de Astrobiología del Instituto Nacional de Técnica Aeroespacial y CSIC, MDM-2017-0737, Agence Nationale de la Recherche (ANR), European Commission (EC), Ministerio de Economía y Competitividad (MINECO), Centre National D'Etudes Spatiales (CNES), Observatoire des Sciences de l'Univers de Grenoble (OSUG), Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry])-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP)-Institut national de recherche en sciences et technologies pour l'environnement et l'agriculture (IRSTEA)-Université Joseph Fourier - Grenoble 1 (UJF)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes (UGA)-Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry])-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP)-Institut national de recherche en sciences et technologies pour l'environnement et l'agriculture (IRSTEA)-Université Joseph Fourier - Grenoble 1 (UJF)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes (UGA)-Centre National d'Études Spatiales [Toulouse] (CNES)-Centre National de la Recherche Scientifique (CNRS), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut national des sciences de l'Univers (INSU - CNRS)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), Centre National de la Recherche Scientifique (CNRS)-Université Joseph Fourier - Grenoble 1 (UJF)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Institut Polytechnique de Grenoble - Grenoble Institute of Technology-Université Grenoble Alpes (UGA)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP), Université Joseph Fourier - Grenoble 1 (UJF)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes (UGA), Institut national des sciences de l'Univers (INSU - CNRS)-Université de Cergy Pontoise (UCP), Université Paris-Seine-Université Paris-Seine-Observatoire de Paris, PSL Research University (PSL)-PSL Research University (PSL)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Perotto, L. [0000-0001-6937-5052], Ponthieu, N. [0000-0002-3101-0768], Marcías Pérez, F. J. [0000-0002-5385-2763], Désert, F. J. [0000-0001-6478-7883], Mayet, F. [0000-0001-9995-4792], Gómez, A. [0000-0002-8752-1401], De Petris, M. [0000-0001-7859-2139], Shu, S. [0000-0002-6370-2101], Mauskpf, P. [0000-0001-6397-5516], Aussel, H. [0000-0002-1371-5705], LabEx FOCUS, ANR-11-LABX-0013, French National Research Agency (ANR), ANR-15-CE31-0017, French National Research Agency in the framework of the 'Investissements d'avenir' program, ANR-15-IDEX-02, European Research Council Advanced Grant ORISTARS under the European Union's Seventh Framework Programme, Spanish Ministerio de Economia and Competitividad (MINECO), and Sapienza Universita' di Roma
Subjects: Physics - Instrumentation and Detectors, media_common.quotation_subject, FOS: Physical sciences, Context (language use), Field of view, Astrophysics, Large scale strcuture of universe, general [Submillimeter], 7. Clean energy, 01 natural sciences, law.invention, Telescope, law, 0103 physical sciences, Calibration, observational [Methods], Angular resolution, instrumentation, photometers, methods, observational, data analysis, submillimeter, general, large-scale structure of Universe, ISM, [PHYS.PHYS.PHYS-INS-DET]Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det], 14. Life underwater, data analysis [Methods], 010306 general physics, 010303 astronomy & astrophysics, Instrumentation and Methods for Astrophysics (astro-ph.IM), Remote sensing, media_common, ISM: general, Physics, general [ISM], Astronomy and Astrophysics, submillimeter: general, Instrumentation and Detectors (physics.ins-det), methods: data analysis, Photometry (astronomy), instrumentation: photometers, photometers [Instrumentation], 13. Climate action, Space and Planetary Science, Sky, Millimeter, methods: observational, Astrophysics - Instrumentation and Methods for Astrophysics, [PHYS.ASTR]Physics [physics]/Astrophysics [astro-ph]
Abstract: Context. NIKA2 is a dual-band millimetre continuum camera of 2 900 kinetic inductance detectors, operating at 150 and 260 GHz, installed at the IRAM 30-m telescope in Spain. Open to the scientific community since October 2017, NIKA2 will provide key observations for the next decade to address a wide range of open questions in astrophysics and cosmology. Aims. Our aim is to present the calibration method and the performance assessment of NIKA2 after one year of observation. Methods. We used a large data set acquired between January 2017 and February 2018 including observations of primary and secondary calibrators and faint sources that span the whole range of observing elevations and atmospheric conditions encountered by the IRAM 30-m telescope. This allowed us to test the stability of the performance parameters against time evolution and observing conditions. We describe a standard calibration method, referred to as the "Baseline"method, to translate raw data into flux density measurements. This includes the determination of the detector positions in the sky, the selection of the detectors, the measurement of the beam pattern, the estimation of the atmospheric opacity, the calibration of absolute flux density scale, the flat fielding, and the photometry. We assessed the robustness of the performance results using the Baseline method against systematic effects by comparing results using alternative methods. Results. We report an instantaneous field of view of 6.5′ in diameter, filled with an average fraction of 84%, and 90% of valid detectors at 150 and 260 GHz, respectively. The beam pattern is characterised by a FWHM of 17.6″ ± 0.1″ and 11.1″ ± 0.2″, and a main-beam efficiency of 47%±3%, and 64%±3% at 150 and 260 GHz, respectively. The point-source rms calibration uncertainties are about 3% at 150 GHz and 6% at 260 GHz. This demonstrates the accuracy of the methods that we deployed to correct for atmospheric attenuation. The absolute calibration uncertainties are of 5%, and the systematic calibration uncertainties evaluated at the IRAM 30-m reference Winter observing conditions are below 1% in both channels. The noise equivalent flux density at 150 and 260 GHz are of 9 ± 1 mJy s1/2 and 30 ± 3 mJy s1/2. This state-of-the-art performance confers NIKA2 with mapping speeds of 1388 ± 174 and 111 ± 11 arcmin2 mJy-2 h-1 at 150 and 260 GHz. Conclusions. With these unique capabilities of fast dual-band mapping at high (better that 18″) angular resolution, NIKA2 is providing an unprecedented view of the millimetre Universe., With funding from the Spanish government through the "María de Maeztu Unit of Excellence" accreditation (MDM-2017-0737)
Published: 2020

130. Estructura interna e invarianza de medición del Children’s Hassles Scale en adolescentes

Author: Jhonatan S. Navarro-Loli and Abílio Afonso Lourenço
Subjects: High probability, validity, Stressor, Sample (statistics), estrés cotidiano, Factor structure, daily stress, cotidiano, Confirmatory factor analysis, Developmental psychology, BF1-990, measurement invariance, validez, Scale (social sciences), Psychology, Measurement invariance, invarianza de medición, Reliability (statistics)
Abstract: Resumen Antecedentes: Los estresores cotidianos son eventos de bajo impacto emocional pero con alta probabilidad de ocurrencia, y en la adolescencia pueden provenir de la escuela, amigos y la familia; por ello es necesario contar con instrumentos para su evaluación. Objetivo: Identificar las evidencias de validez de la estructura interna e invarianza de medición del Children’s Hassles Scale en adolescentes de Lima, Perú. Método: La muestra estuvo conformada por 524 adolescentes entre los 14 y 18 años. La estructura interna se evaluó mediante el análisis factorial confirmatorio y la invarianza de medición mediante un procedimiento en que se agregan restricciones progresivamente, finalmente, la confiabilidad se obtuvo con el coeficiente omega. Resultados: La estructura factorial original no se replica en la muestra peruana, por el contrario, una estructura parsimoniosa de dos factores oblicuos orientados a factores estresantes en el colegio y la familia es la que presenta indicadores robustos e invarianza de medición entre varones y mujeres. Conclusión: Se puede utilizar el instrumento para fines de investigación en el contexto peruano, el cual carece de instrumentos para la medición de estresores cotidianos en adolescentes. Abstract Background: Daily stressors are events of low emotional impact but with high probability of occurrence, which in adolescence can come from school, friends and family. Therefore, it is necessary to have instruments for their evaluation. Aim: To determine the validity of the internal structure and measurement invariance of the Children’s Hassles Scale in adolescents from Lima, Peru. Method: The sample consisted of 524 adolescents between 14 and 18 years old. The internal structure was evaluated by confirmatory factor analysis, and the measurement invariance was assessed using a procedure in which restrictions were added progressively. Finally, reliability was obtained through coefficient omega. Results: The original factor structure is not replicated in the Peruvian sample. On the contrary, a parsimonious structure of two oblique factors oriented to stressors in school and family presents robust indicators and measurement invariance among males and females. Conclusion: The instrument can be used for research purposes in the Peruvian setting, which lacks instruments for measuring daily stressors in adolescents.
Published: 2020

131. Estructura Interna del Cognitive Emotion Regulation Questionnaire (CERQ-18) en una Muestra de Adolescentes Peruanos

Author: Jhonatan S. Navarro-Loli, Leonardo Adrián Medrano, and Sergio Dominguez-Lara
Subjects: Analisis factorial, Psychology, Humanities, General Psychology
Abstract: espanolEl presente estudio tuvo como objetivo identificar las evidencias de validez de la estructura interna y en relacion con otras variables del Cognitive Emotion Regulation Questionnaire (CERQ-18) en adolescentes peruanos. La muestra fue de 255 adolescentes entre los 13 y 19 anos (Medad 15.494, DEedad=1.192) de una Institucion Educativa publica del distrito de Ventanilla (Peru). Los instrumentos utilizados fueron el CERQ18 y el Inventario de Depresion Estado/Rasgo. Se plantearon cuatro hipotesis estructurales que fueron evaluados mediante un analisis factorial confirmatorio, incluyendo analisis bifactor. Los resultados indican que el modelo evolucionista representadas por las estrategias automaticas (autoculpa, rumiacion, catastrofizacion) y elaborativas (aceptacion, focalizacion en los planes, reinterpretacion positiva, focalizacion positiva y poner en perspectiva), presentan indicadores satisfactorios, favoreciendo su interpretacion, y mostrando relaciones significativas con afecto positivo y negativo. Se concluye que la estructura interna del CERQ-18 en adolescentes es respaldada por el modelo evolucionista. EnglishThe present study aimed to identify the evidence of validity of the internal structure and in relation to other variables of the Cognitive Emotion Regulation Questionnaire (CERQ-18) in peruvian adolescents. The sample consisted of 255 adolescents between the ages of 13 and 19 (M=15.494, DE=1.192) from a public school of the district of Ventanilla (Peru). The instruments used were the CERQ-18 and the State / Trait Depression Inventory. Four structural hypotheses were proposed, which were evaluated by confirmatory factor analysis, including bifactor analysis. The results indicate that the evolutionary model represented by automatic (self-blame, rumination, catastrophization) and deliberate strategies (acceptance, refocus on planning, positive reappraisal, positive refocusing and putting into perspective), present satisfactory indicators, favoring their interpretation, and showing significant relationships with positive and negative affect. It is concluded that the internal structure of CERQ-18 in adolescents is supported by the evolutionary model.
Published: 2020

132. Association between environmental exposure to pesticides and epilepsy

Author: Raquel Alarcón, Mar Requena, A. S. Navarro, Jessica García, Antonio F. Hernández, María Isabel Ventura, and Tesifón Parrón
Subjects: Adult, Male, Population, 010501 environmental sciences, Toxicology, 01 natural sciences, 03 medical and health sciences, Epilepsy, 0302 clinical medicine, Environmental health, Health care, Humans, Medicine, Pesticides, education, Association (psychology), 0105 earth and related environmental sciences, education.field_of_study, business.industry, General Neuroscience, Environmental Exposure, Environmental exposure, Middle Aged, Pesticide, medicine.disease, Control subjects, Spain, Case-Control Studies, Population study, Female, business, 030217 neurology & neurosurgery
Abstract: There is increasing evidence of an association between long-term environmental exposure to pesticides and neurodegenerative disorders; however, the relationship with epilepsy has not been addressed thus far. This study was aimed at determining the prevalence and risk of developing epilepsy among people from South-East Spain living in areas of high vs. low exposure to pesticides based on agronomic data. The study population consisted of 4007 subjects with a diagnosis of epilepsy and 580,077 control subjects adjusted for age, sex and geographical area. Data were collected from hospital records of the Spanish health care system (basic minimum dataset) between the years 1998 and 2010. The prevalence of epilepsy was significantly higher in areas of greater pesticide use relative to areas of lesser use. Overall, an increased risk of epilepsy was observed in the population living in areas of high vs. low use of pesticides (OR: 1.65; p 0.001). Although this study was exploratory in nature, the results suggest that environmental exposure to pesticides might increase the risk of having epilepsy.
Published: 2018

133. Tratamiento endoscópico en pacientes con estenosis subglótica

Author: D Mónica A Ladino, R Luis Jorge Morales, Leonardo E Ordóñez-Ordóñez, and Usmaila S Navarro G
Subjects: Psychiatry and Mental health
Abstract: Objetivos: Determinar cuáles son los tipos de estenosis subglótica que pueden ser manejados por vía endoscópica. Diseño: Estudio observacional, descriptivo, tipo serie de casos. Métodos: La medición principal es el éxito/fracaso con el manejo endoscópico. Se tomaron 83 pacientes con estenosis subglótica, con manejo endoscópico; la información fue completa en 65 casos. La edad media fue de 22,3 años, 53 hombres y 12 mujeres; 40 tuvieron estenosis simples, 25 complejas. Resultados: No hubo asociación manifiesta entre el éxito y el procedimiento endoscópico, la edad y la localización de la estenosis. Hubo diferencias significativas entre la medición principal (éxito/fracaso) y las variables de porcentaje de estenosis (61,1% vs. 81,7%), longitud de la estenosis (1,1 cm vs. 2,2 cm), sitio comprometido (simples-éxito = 80%, complejas-éxito = 25%) y consistencia (blanda-éxito = 86%, dura-éxito = 44%). Conclusiones: Los procedimientos endoscópicos tienden a ser exitosos en estenosis simples, blandas, con porcentajes de estenosis ≤ 62% y longitud de la estenosis ≤ 1,1 cm.
Published: 2018

134. The Mexican Asteroid Photometry Campaigns: Aiming for Asteroids’ Rotation Periods

Author: Julio C. Saucedo, R. Vázquez, W. J. Schuster, A. Avilés, P. A. Valdés-Sada, S. A. R. Haro-Corzo, M. E. Contreras, I. L. Fuentes-Carrera, L. Olgun, M. Rodrguez-Martnez, Eduardo Pérez-Tijerina, Juan Segura-Sosa, S. Navarro-Meza, Pablo Loera-González, C. Chávez-Pech, S. A. Ayala-Gómez, and Mauricio Reyes-Ruiz
Subjects: Photometry (astronomy), Space and Planetary Science, Asteroid, Astronomy, Astronomy and Astrophysics, Geology
Abstract: Thousands of new asteroids are discovered every year and the rate of discovery is by far larger than the determination rate of their physical properties. In 2015 a group of researchers and students of several Mexican institutions have established an observational program to study asteroids photometrically. The program, named Mexican Asteroid Photometry Campaign, is aiming to derive rotation periods of asteroids based on optical photometric observations. Since then four campaigns have been carried out. The results obtained throughout these campaigns, as well as future work, are presented.
Published: 2018

135. On the Use of the EMOTIV Cortex API to Control a Robotic Arm Using Raw EEG Signals Acquired from the EMOTIV Insight NeuroHeadset

Author: Diego S. Benitez, Ivan N. Zamora, and Manuel S. Navarro
Subjects: MQTT, Application programming interface, medicine.diagnostic_test, Computer science, Headset, 05 social sciences, Real-time computing, 020206 networking & telecommunications, 02 engineering and technology, Electroencephalography, Python (programming language), WebSocket, 0502 economics and business, 0202 electrical engineering, electronic engineering, information engineering, medicine, Robotic arm, computer, 050203 business & management, Brain–computer interface, computer.programming_language
Abstract: This paper explores the feasibility of using the Emotiv Cortex Application Programming Interface (API) service to obtain raw sensor signals from the Emotiv Insight NeuroHeadset for the control of a robotic arm. A data acquisition software based on Python was developed to use the service through data streaming in a Websocket. Raw EEG and motion sensor signals from the headset were processed for event detection. Detected events were then used to trigger control signals to a robotic arm controlled by a Raspberry Pi 3 using the IoT MQTT protocol. The results obtained indicate that the proposed approach and the algorithms developed were adequate translated into valid commands for effective development of a Head-Computer Interface that enables complete interaction with a robotic arm.
Published: 2019

136. Consenso Mexicano para el Tratamiento de la Hepatitis C

Author: A.M. Pérez-Ríos, G.E. Castro-Narro, E.R. Marín-López, Omar D. Borjas-Almaguer, L.E. Cisneros-Garza, Judith Flores-Calderón, Linda E. Muñoz-Espinosa, D. Kershenobich-Stalnikowitz, Margarita Dehesa-Violante, R.A. Chirino-Sprung, M. Castillo-Barradas, J.A. Velarde-Ruiz Velasco, R. Torres-Ibarra, E. López-Méndez, Norberto C. Chávez-Tapia, M.S. González-Huezo, R. Trejo-Estrada, A. Ballesteros-Amozurrutia, S. Navarro-Alvarez, R. Sandoval-Salas, Juan Francisco Sánchez-Ávila, Francisco Bosques-Padilla, R. Moreno-Alcántar, E. Wolpert-Barraza, J.L. Poo-Ramírez, M.T. Rizo-Robles, Aldo Torre, A. Flores-Gaxiola, Emmanuel I. Gonzalez-Moreno, Ignacio García-Juárez, Roberto Monreal-Robles, N. Pavia-Ruz, Nahum Méndez-Sánchez, R. Malé-Velázquez, F. Higuera-de la Tijera, J.A. Mata-Marín, and I. Aiza-Haddad
Subjects: 03 medical and health sciences, 0302 clinical medicine, Gastroenterology, 030211 gastroenterology & hepatology, lcsh:Diseases of the digestive system. Gastroenterology, 030212 general & internal medicine, lcsh:RC799-869
Abstract: Resumen: El objetivo del Consenso Mexicano para el Tratamiento de la Hepatitis C fue el de desarrollar un documento como guía en la práctica clínica con aplicabilidad en México. Se tomó en cuenta la opinión de expertos en el tema con especialidad en: gastroenterología, infectología y hepatología. Se realizó una revisión de la bibliografía en MEDLINE, EMBASE y CENTRAL mediante palabras claves referentes al tratamiento de la hepatitis C. Posteriormente se evaluó la calidad de la evidencia mediante el sistema GRADE y se redactaron enunciados, los cuales fueron sometidos a voto mediante un sistema modificado Delphi, y posteriormente se realizó revisión y corrección de los enunciados por un panel de 34 votantes. Finalmente se clasificó el nivel de acuerdo para cada oración. Esta guía busca dar recomendaciones con énfasis en los nuevos antivirales de acción directa y de esta manera facilitar su uso en la práctica clínica. Cada caso debe ser individualizado según sus comorbilidades y el manejo de estos pacientes siempre debe ser multidisciplinario. Abstract: The aim of the Mexican Consensus on the Treatment of Hepatitis C was to develop clinical practice guidelines applicable to Mexico. The expert opinion of specialists in the following areas was taken into account: gastroenterology, infectious diseases, and hepatology. A search of the medical literature was carried out on the MEDLINE, EMBASE, and CENTRAL databases through keywords related to hepatitis C treatment. The quality of evidence was subsequently evaluated using the GRADE system and the consensus statements were formulated. The statements were then voted upon, using the modified Delphi system, and reviewed and corrected by a panel of 34 voting participants. Finally, the level of agreement was classified for each statement. The present guidelines provide recommendations with an emphasis on the new direct-acting antivirals, to facilitate their use in clinical practice. Each case must be individualized according to the comorbidities involved and patient management must always be multidisciplinary. Palabras clave: Consenso, Agentes antivirales de acción directa, Regímenes libres de interferón, Ribavirina, Keywords: Consensus, Direct-acting antiviral agents, Interferon-free regimens, Ribavirin
Published: 2018

137. The Mexican consensus on the treatment of hepatitis C

Author: R. Sandoval-Salas, Juan Francisco Sánchez-Ávila, L.E. Cisneros-Garza, R.A. Chirino-Sprung, I. Aiza-Haddad, F. Higuera-de la Tijera, Omar D. Borjas-Almaguer, R. Trejo-Estrada, M.T. Rizo-Robles, R. Torres-Ibarra, Aldo Torre, M.S. González-Huezo, Judith Flores-Calderón, Margarita Dehesa-Violante, J.L. Poo-Ramírez, Norberto C. Chávez-Tapia, Emmanuel I. Gonzalez-Moreno, A. Flores-Gaxiola, Ignacio García-Juárez, J.A. Mata-Marín, E.R. Marín-López, Nahum Méndez-Sánchez, D. Kershenobich-Stalnikowitz, R. Malé-Velázquez, J.A. Velarde-Ruiz Velasco, Linda E. Muñoz-Espinosa, Roberto Monreal-Robles, Francisco Bosques-Padilla, E. Wolpert-Barraza, S. Navarro-Alvarez, G.E. Castro-Narro, R. Moreno-Alcántar, M. Castillo-Barradas, N. Pavia-Ruz, E. López-Méndez, A.M. Pérez-Ríos, and A. Ballesteros-Amozurrutia
Subjects: medicine.medical_specialty, business.industry, media_common.quotation_subject, education, Grade system, MEDLINE, General Medicine, Hepatitis C, medicine.disease, Patient management, Quality of evidence, 03 medical and health sciences, 0302 clinical medicine, Multidisciplinary approach, Family medicine, Voting, medicine, 030211 gastroenterology & hepatology, 030212 general & internal medicine, business, Medical literature, media_common
Abstract: The aim of the Mexican Consensus on the Treatment of Hepatitis C was to develop clinical practice guidelines applicable to Mexico. The expert opinion of specialists in the following areas was taken into account: gastroenterology, IFNectious diseases, and hepatology. A search of the medical literature was carried out on the MEDLINE, EMBASE, and CENTRAL databases through keywords related to hepatitis C treatment. The quality of evidence was subsequently evaluated using the GRADE system and the consensus statements were formulated. The statements were then voted upon, using the modified Delphi system, and reviewed and corrected by a panel of 34 voting participants. Finally, the level of agreement was classified for each statement. The present guidelines provide recommendations with an emphasis on the new direct-acting antivirals, to facilitate their use in clinical practice. Each case must be individualized according to the comorbidities involved and patient management must always be multidisciplinary.
Published: 2018

138. P2472Two-dimensional speckle tracking echocardiography in heart transplant patients: five year follow-up of right and left ventricular function

Author: S. Mingo Santos, A Borrego Hernandez, V Monivas Palomero, J. Segovia Cubero, S Lozano Jimenez, M. Gomez Bueno, L. Alonso Pulpon, M. A. Cavero Gibanel, S Navarro Rico, and J. Goirigolzarri Artaza
Subjects: medicine.medical_specialty, Ventricular function, business.industry, Internal medicine, Cardiology, medicine, Five year follow up, Transplant patient, Speckle tracking echocardiography, Cardiology and Cardiovascular Medicine, business
Abstract: Background Evolution of left and right ventricular (LV and RV) function after heart transplantation (HT) has not been well described. Our objective was to evaluate the normal evolution of echocardiographic parameters of both ventricles and to explore if there is a link between the decrease of strain values and acute rejection (AR) or coronary allograft vasculopathy (CAV) Methods We followed 29 HT recipients with serial echocardiograms performed between 2011 and 2018, with a median follow-up of 5 years. LV global longitudinal strain (LV GLS) was analyzed by speckle tracking in 12 LV segments in 4 and 2 chamber views, and RV free wall longitudinal strain (RV free Wall LS) was measured in 4 chamber view. Acute rejection was diagnosed by EMB following our HT protocol. We take into consideration only moderate or severe rejection episodes (grade ≥2R).The presence of CAV was studied by coronariography or IVUS one year post-HT. Results As shown in the table below, LVEF was preserved from the begining of the follow up while LV GLS reached the normality in the 6th month, and both remained in normal ranges untill the 5th year. Regarding RV function, TAPSE was impaired in the early post-HT period and increased progressively and reached normality 1 year after HT. RV lateral wall LS rose during follow-up as well, reaching normal values 6 months after HT. Nevertheless, we noticed an impairment in this parameter at 5 years (−20.1±2.7, p=0.001), although it remained within normal ranges compared to guidelines reference parameters. We did not find any correlation between any parameter evaluated and the presence of AR or CAV at five years of follow-up. LV and RV function parameters LVEF LV GLS TAPSE FAC RV free wall LS Basal (14 days) 63.0±7.9 −17.2±3.6 12.1±2.9* 43.7±9.8 −19.3±4.2 3 months 65.0±8.6 −17.7±2.8 14.8±3.4* 45.3±8.2 −22.0±4.6 6 months 65.8±9.6 −18.7±3.4 16.1±3.6 44.6±9.6 −24.6±4.9* 1 year 63.5±8.1 −18.1±2.2 17.1±4.1 44.0±8.1 −26.7±7.1* 2 years 63.8±6.8 −18.3±9.0 19.4±3.7 45.3±7.9 −27.6±6.3* 5 years 64.4±7.3 −18.1±3.3 17.9±3.9 46.6±12.1 −20.1±2.8 P (Anova) 0.85 0.85 Conclusion As we show in this series of HT recipients with uneventful postoperative course, all LV and RV function parameters showed normal values 1 year after HT and manteined them during long-term follow-up. The presence of AR or CAV did not have any influence in ventricular function.
Published: 2019

139. P1820New parameters for the evaluation of mechanic and elastic properties of the aortic root in Marfan Syndrome

Author: C. Mitroi, J. Gonzalez Mirelis, J Baena Herrera, E Garcia Izquierdo Jaen, C.E. Martin Lopez, S. Mingo Santos, A. Forteza Gil, V Monivas Palomero, S Navarro Rico, C Aguilera Agudo, and M Torres Sanabria
Subjects: Marfan syndrome, medicine.medical_specialty, business.industry, Aortic root, Internal medicine, cardiovascular system, Cardiology, Medicine, Cardiology and Cardiovascular Medicine, business, medicine.disease
Abstract: Background Elastic properties of the thoracic aorta in patients with Marfan Syndrome (MS) have already been evaluated with classic echocardiographic parameters. In the latest years the use of Speckle-Tracking (STE) ecocardiography has been widely extended. Our aim is to describe and provide new parameters of aortic deformation measured by STE in patients with MS. Methods 95 unoperated adult patients with MS and 32 healthy controls were prospectively enrolled. We measured classic parameters of the aortic root using 2D echocardiography. We calculated the posterior aortic wall systolic excursion at the sinuses of Valsalva and ascending aorta using M Mode in TDI colour; with ST 2D ecocardiography we measured the aortic strain at the sinuses of Valsalva (SV) and the anterior and posterior aortic wall displacement at the SV. Aortic distensibility was calculated using the formula: 1000 * (Ds − Dd)/Dd * 1/(Ps − Pd) in mmHg–1 (Ds: systolic and Dd: diastolic diameters, Ps systolic and Pd diastolic blood pressure). Aortic stiffness index was calculated as Ln((Ps/Pd)/(Ds-Dd)/Dd)). Results As shown in the table bellow, patients with MS had lower aortic strain, aortic anterior and posterior wall displacement and impaired aortic distensibility and stiffness index compared to healthy controls. We found a strong negative linear correlation between aortic root diameter at the SV and aortic root strain (r=−0.56, figure 1). Results of statistical analysis MS (n=95) Controls (n=32) p Age (years) 32.84±12.35 32.41±7.98 0.85 Aortic root diameter at the sinuses of Valsalva (mm) 38.82±5.35 30.92±3.65 Figure 1. Dispersion plot Conclusions Our results suggest that aortic deformation and displacement obtained by STE echocardiography is impaired in MS, showing a reduced distensibility and an increased stiffness of the aortic wall, with a strong negative correlation between aortic root dilation and aortic strain. All these parameters may be useful as additional tools for the diagnosis and follow-up of Marfan patients, and could be useful to to improve the echocardiographic evaluation of the aortic root.
Published: 2019

140. P4374Biventricular systolic function analysis in patients with Marfan Syndrome using speckle-tracking 2D ecocardiography

Author: J. Gonzalez Mirelis, S Navarro Rico, J Baena Herrera, C. Mitroi, V Monivas Palomero, S. Mingo Santos, A. Forteza Gil, M Torres Sanabria, C Aguilera Agudo, C.E. Martin Lopez, and E Garcia Izquierdo Jaen
Subjects: Marfan syndrome, Speckle pattern, medicine.medical_specialty, business.industry, Internal medicine, medicine, Cardiology, In patient, Systolic function, Cardiology and Cardiovascular Medicine, medicine.disease, Tracking (particle physics), business
Abstract: Background Left Ventricular systolic disfunction has already been described in Marfan Syndrome (MS) in patients without valvular dysfunction using 2D and 3D speckle tracking echocardiography (STE). This dysfunction has been related to a more severe causal genetic mutation, which suggest the presence of a primary cardiomiopathy in these patients. Right ventricular function has been less studied so far. We sought to evaluate biventricular function in our cohort of MS patients with 2D-STE. Methods 95 unoperated adult patients with MS and 32 healthy controls were prospectively enrolled. Patients with more than mild mitral or aortic regurgitation were excluded. Using STE we obtanied left ventricular global longitudinal strain (LVGLS) from the average of 16 segments from 4,2 and 3-chamber views and RVGLS values were obtained from the average of 6 segments from the apical 4-chamber view. We also measured classic parameters of systolic biventricular function (LVEF and TAPSE). Results Compared to controls, patients with MFS had significantly lower LVGLS and RVGLS (table 1). Values obtanied for LVGLS in MS patients were at the lower limit of normality stablished in the latest cuantification guidelines, while RVGLS and RV free wall LS were slightly above the limit of normality. LVEF and TAPSE were also slightly diminished in MS patients, though the differences found were clinically not relevant. Results of statistical analysis MS (n=93) Controls (n=32) p Age (years) 32.84±12.4 32.41±7.98 0.85 Aortic Root Diameter Valsalva Sinuses (mm) 38.82±5.35 30.91±5.3 Conclusions Our study suggests that patients with MFS show lower biventricular strain compared with healthy controls. 2D-STE imaging may be useful to detect subclinical changes in cardiac function in patients with MFS and should be added to routine ecocardiographic evaluation in order to improve the follow-up and treatment of these patients.
Published: 2019

141. P4372Left atrial strain: a potential marker of early diastolic dysfunction in patients with Marfan syndrome

Author: E Garcia-Izquierdo Jaen, S. Mingo Santos, C. Mitroi, S Moreno Casado, A. Forteza Gil, J. Gonzalez Mirelis, D Martinez Lopez, M Torres Sanabria, C.E. Martin Lopez, S Navarro Rico, M. A. Cavero Gibanel, and V Monivas Palomero
Subjects: Marfan syndrome, Atrial strain, medicine.medical_specialty, business.industry, Internal medicine, medicine, Cardiology, Early diastolic, In patient, Cardiology and Cardiovascular Medicine, medicine.disease, business
Abstract: Background/Introduction Previous studies using conventional echocardiographic measurements have reported subclinical left diastolic dysfunction in patients with Marfan syndrome (MFS). Left atrial strain (LAS) has been shown to be an accurate predictor of left ventricular diastolic dysfunction. However, there is no evidence regarding the use of LAS in MFS. Purpose To assess feasibility of LAS and compare LAS derived measurements along with traditional diastolic parameters in MFS patients vs healthy controls. Methods 46 MFS patients (normal LV ejection fraction, no previous cardiovascular surgery, no significant valvular regurgitation) vs. 20 healthy controls (age and sex-matched). We performed LAS analysis using 2D speckle-tracking (QLAB 10, Philips). LA strain was determined as the average value of the longitudinal deformation (7 segments) in the apical 4-chamber view (RR gating). Results LAS analysis was feasible in 40 MFS patients (87%). All participants had normal diastolic function according to current guidelines (ASE/EACVI 2016). MFS patients showed lower TDI e' velocities and higher average E/e' ratio, but still within normal range. Similarly, LVEF was normal but slightly reduced in MFS patients. LA strain and strain rate parameters during reservoir and conduit phase were significantly impaired in MFS patients compared to controls. MFS vs controls MFS patients (n=40) Controls (n=20) p MFS patients (n=40) Controls (n=20) p Age 33.8±12.4 34.4±8.3 0.846 Septal e' (cm/s) 9.7±2.5 11.7±2.3 0.006 Male (%) 24 (60%) 12 (60%) 1.000 Average E/e' ratio 6.8±1.5 5.5±1.1 0.002 SBP (mmHg) 120.3±12.4 120.1±9.4 0.969 TR velocity (cm/s) 208.6±21.4 201.6±22.9 0.390 DBP (mmHg) 72.0±10.1 67.1±6.2 0.069 LAVi (ml/m2) 23.5±7.1 25.5±4.8 0.260 Aortic root (mm) 40.3±4.6 31.7±3.7 Example of LA strain and strain rate Conclusion MFS patients showed a subtle impairment in diastolic function compared to controls. Although further evidence is needed, LAS derived parameters could be early markers of diastolic dysfunction in this group of patients. Acknowledgement/Funding Programa de Actividades de I+D de la Comunidad de Madrid
Published: 2019

142. Life-cycle assessment of bioethanol production from sweet sorghum stalks cultivated in the state of Yucatan, Mexico

Author: Patricia Aguilar-Sánchez, Freddy S. Navarro-Pineda, Luis Felipe Barahona-Pérez, and Julio C. Sacramento-Rivero
Subjects: Economics and Econometrics, Environmental Engineering, business.industry, 020209 energy, Biomass, 02 engineering and technology, 010501 environmental sciences, Management, Monitoring, Policy and Law, Pulp and paper industry, 01 natural sciences, General Business, Management and Accounting, Renewable energy, Bioenergy, Biofuel, 0202 electrical engineering, electronic engineering, information engineering, Environmental Chemistry, Environmental science, Ethanol fuel, Bagasse, business, Sweet sorghum, Life-cycle assessment, 0105 earth and related environmental sciences
Abstract: Bioethanol is being promoted in Mexico to be used in a blend with gasoline. On the north of the Yucatan peninsula, bioethanol could be produced from sweet sorghum, as it can grow efficiently on this land; it can be harvested 2–3 times in a year and possesses a better agronomical stability than sugarcane with low nitrogen requirements and high productivity. In this work , the potential environmental impacts and energy efficiency of bioethanol production from sweet sorghum were evaluated using life-cycle assessment. Four scenarios were evaluated: scenario PI considered only bioethanol production from the stalk juice; scenarios PII and PIII added cogeneration from the dry-stalk biomass in single and combined cycle, respectively. Scenario PIV considered bioethanol production from both stalk juice and dry-stalk biomass. Scenario PI demanded more fossil energy than what was generated as bioethanol, while scenarios PII and PIII were fossil energy independent. Scenario PIII showed the higher net energy ratio (1.89) and a better environmental performance in all CML-IA baseline impact categories. In terms of global warming potential, the scenario PIII showed a mitigation potential of 16% with respect to the fossil reference. In the categories where the sweet sorghum scenarios represented larger emissions than the fossil reference, it was due mainly to the use of fertilizers and the conventional energy consumption in the various processing steps of the biomass. Scenario PIV showed the highest energy demand and worst environmental performance due to large demands of energy and chemicals in the bagasse pretreatment step.
Published: 2018

143. Estudio de selección de microRNA como posibles biomarcadores de aneurisma de aorta abdominal

Author: Manuel Miralles, L. Gálvez, P. Medina, S. Navarro, and Emma Plana
Subjects: 0301 basic medicine, 03 medical and health sciences, 030104 developmental biology, Cardiology and Cardiovascular Medicine
Abstract: Resumen Introduccion Los microRNA (miR) son RNA de pequeno tamano involucrados en la regulacion de numerosos procesos biologicos. Debido a su estabilidad y a su capacidad para detectarse en fluidos, se han convertido en objeto de estudio como posibles biomarcadores de diferentes patologias. Objetivo Seleccionar un numero reducido de miR candidatos a ser biomarcadores de aneurisma de aorta abdominal (AAA). Material y metodos Se determino la expresion de 179 miR en el plasma de 7 pacientes y 7 voluntarios sanos, mediante paneles predisenados, basados en la tecnologia de RT-qPCR. Resultados Hemos seleccionado 10 miR disregulados en pacientes como buenos candidatos para su estudio como biomarcadores debido a su implicacion en diversos procesos biologicos relacionados con el desarrollo y evolucion de AAA. Conclusiones Aunque son necesarios estudios adicionales y de validacion, algunos de estos miR podrian ser biomarcadores no invasivos de AAA.
Published: 2018

144. Potential effects of the Mexican energy reform on life cycle impacts of electricity generation in Mexico and the Yucatan region

Author: Julio C. Sacramento-Rivero, Robert M. Handler, and Freddy S. Navarro-Pineda
Subjects: Consumption (economics), Renewable Energy, Sustainability and the Environment, business.industry, Natural resource economics, 020209 energy, Strategy and Management, National power, 02 engineering and technology, Building and Construction, Industrial and Manufacturing Engineering, Electricity generation, Environmental protection, Scale (social sciences), 0202 electrical engineering, electronic engineering, information engineering, Environmental science, Environmental impact assessment, Electricity, business, Baseline (configuration management), Life-cycle assessment, General Environmental Science
Abstract: A national energy strategy in Mexico to 2028, derived from the recent energy reform, projects a considerable shift in the national power generation mix leading to changes on its environmental profile. Therefore, this paper aims to compare the potential environmental impacts of the electricity generation under previous, current and projected energy mixes in Mexico at a national and regional scale considering the Yucatan state as the regional case study. These were estimated with a cradle-to-grave Life Cycle Assessment (LCA) following the CML–IA 2000 V2.05 methodology and including the baseline environmental impact categories. Results indicate that the environmental impacts per generated kWh of electricity have decreased in Mexico from 2007 to 2013 and would keep decreasing at a faster rate until 2028 according to current projections. In Yucatan, the environmental impacts increased from 2007 to 2013 due to an increased diesel consumption, but would decrease by 2028 reaching lower levels than in 2007. From 2007 to 2013 almost all the environmental impacts in Yucatan were lower than the country average due to a higher contribution of natural gas in the power generation mix, while in 2028 they would be similar. Overall, there is a significant difference between the national and regional estimations of the potential environmental impacts due to differences in their power generation mix. Furthermore, the potential introduction of shifts derived from the energy reform in Mexico will have a strong positive influence on the environmental impacts from the electricity generation.
Published: 2017

145. On the Chlorination Thermodynamics

Author: E., Brocchi, primary and C. S., Navarro R., additional
Published: 2011
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146. Effects Of Forearm Cooling On Thermal Responses And Exercise Performance During Intermittent Exercise In The Heat

Author: Erica M. Filep, Erin E. Dierickx, Douglas J. Casa, Megan Nye, John S. Navarro, and Michael R Szymanski
Subjects: medicine.medical_specialty, medicine.anatomical_structure, Physical medicine and rehabilitation, Forearm, business.industry, Exercise performance, medicine, Physical Therapy, Sports Therapy and Rehabilitation, Orthopedics and Sports Medicine, business
Published: 2021

147. Combined iodinated radiographic contrast and Tc99 radioisotope (i-ROLL) as technical improvement for the preoperative localization of non-palpable breast lesions: A comparative study with ROLL

Author: M. Medarde Ferrer, A.Martin Oloriz, S. Navarro Soto, J.C. Martin Miramón, O. Aparicio Rodriguez, J. Del Riego Ferrari, and V. Lucas Guerrero
Subjects: Cancer Research, Oncology, business.industry, media_common.quotation_subject, Radiography, Contrast (vision), Medicine, Non palpable, business, Nuclear medicine, media_common
Published: 2020

148. Impact of RES Penetration on the Frequency Dynamics of the 500 kV Vietnamese Power System

Author: Favuzza, S., primary, Navia, M. S. Navarro, additional, Musca, R., additional, Sanseverino, E. Riva, additional, Zizzo, G., additional, Doan Van, B., additional, and Quang, N. Nguyen, additional
Published: 2019
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149. Research on depression in adolescents in Peru: a systematic review

Author: Manolete S. Moscoso, Gustavo Calderón-De la Cruz, and Jhonatan S. Navarro-Loli
Subjects: SciELO, medicine.medical_specialty, Public health, depresión, Scopus, adolescentes, Library science, Context (language use), Unit of analysis, BF1-990, systematic review, depression, medicine, revisión sistemática, Psychology, adolescents, Construct (philosophy), Social psychology
Abstract: Depression in adolescents is a multicausal phenomenon and a predictor of social problems and other disorders. Thus, it is considered a public health problem. This investigation aims to systematically review the characteristics of the scientific articles about depression in Peruvian adolescents published in Peruvian and non-Peruvian journals. The search was performed in the databases of SciELO, Latindex, Redalyc, Scopus, PubMed, and through Google, using a combination of keywords related to the construct, the sample and its origin. The unit of analysis consisted of 21 articles. The reviewed articles showed inconsistency in the reporting and bibliographic support of the research designs, sampling procedures, psychometric properties of the instruments, instruments used to assess the construct which were not evaluated in our context, and cut-off points obtained in other countries’ samples. Therefore, we can state that the reviewed articles do not fully comply with the publication standards proposed by the American Psychological Association. DOI:https://doi.org/10.24265/liberabit.2017.v23n1.04 La depresión en adolescentes es una problemática multicausal y predictora de problemas sociales y otros trastornos. Por ello, es considerada un problema de salud pública. El objetivo de la presente investigación es realizar una revisión sistemática de las características de los artículos científicos publicados en revistas peruanas y no peruanas sobre depresión en adolescentes peruanos. La búsqueda se realizó en las bases de datos Scielo, Latindex, Redalyc, Scopus, PubMed y a través de Google, utilizando combinación de palabras clave relacionadas al constructo, la muestra y su procedencia. La unidad de análisis estuvo conformada por 21 artículos. En los estudios destaca la inconsistencia en el reporte y sustento bibliográfico del diseño de investigación, del procedimiento de muestreo y de las propiedades psicométricas de los instrumentos; también, de la utilización de instrumentos que no han sido evaluados en nuestro contexto y de puntos de corte obtenidos en muestras de otros países. Debido a ello, se puede afirmar que los estudios no cumplen en su totalidad con los estándares de publicación propuestos por la American Psychological Association. DOI:https://doi.org/10.24265/liberabit.2017.v23n1.04
Published: 2017

150. Primary laryngeal sarcomas in a Mexican population: Case series of eleven cases

Author: Verónica Villavicencio-Valencia, Rosa A. Salcedo-Hernández, Kuauhyama Luna-Ortiz, J.A. Delgado, S. Navarro-Santiesteban, and Leonardo S. Lino-Silva
Subjects: Adult, Male, Pediatrics, medicine.medical_specialty, Treatment outcome, MEDLINE, Disease-Free Survival, Cohort Studies, Young Adult, 03 medical and health sciences, 0302 clinical medicine, medicine, Humans, Young adult, 030223 otorhinolaryngology, Laryngeal Neoplasms, Mexico, Survival rate, Aged, Aged, 80 and over, Series (stratigraphy), business.industry, Sarcoma, Middle Aged, medicine.disease, Mexican population, Survival Rate, Treatment Outcome, Otorhinolaryngology, 030220 oncology & carcinogenesis, Female, business, Cohort study
Published: 2017

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