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105. Making sustainability rankings using compromise programming. An application to European paper industry

Author

Diaz-Balteiro, Luis, Voces, Roberto, and Romero, Carlos

Subjects
Forestry, SD1-669.5
Abstract

This paper characterizes the sustainability of the European paper industry. To undertake this task the sustainability of each country is defined by using fourteen indicators of a diverse nature (economic, environmental and social). These indicators are aggregated into a composite or synthetic index with the help of a compromise programming model. In order to associate different weights with each indicator, a survey among international experts has been carried out. In this way, a ranking of seventeen European countries analysed in terms of the sustainability of the European paper industry has been established, where Finland is the most sustainable paper industry in Europe except when the most balanced solution is chosen. Also, the results are robust when different preferential weights are attached. Finally, this methodology can be applied at a more disaggregated level and other indicators can be introduced.

Published
2011
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106. Selection scan in Native Americans of Mexico identifies FADS2 rs174616: Evidence of gene-diet interactions affecting lipid levels and Delta-6-desaturase activity

Author

Romero-Hidalgo, Sandra, Sagaceta-Mejía, Janine, Villalobos-Comparán, Marisela, Tejero, María Elizabeth, Domínguez-Pérez, Mayra, Jacobo-Albavera, Leonor, Posadas-Sánchez, Rosalinda, Vargas-Alarcón, Gilberto, Posadas-Romero, Carlos, Macías-Kauffer, Luis, Vadillo-Ortega, Felipe, Contreras-Sieck, Miguel Angel, Acuña-Alonzo, Víctor, Barquera, Rodrigo, Macín, Gastón, Binia, Aristea, Guevara-Chávez, Jose Guadalupe, Sebastián-Medina, Leticia, Menjívar, Martha, Canizales-Quinteros, Samuel, Carnevale, Alessandra, and Villarreal-Molina, Teresa

Published
2024
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122. Genome-Wide Association Study Identifies a Functional SIDT2 Variant Associated With HDL-C (High-Density Lipoprotein Cholesterol) Levels and Premature Coronary Artery Disease

Author

León-Mimila, Paola, Villamil-Ramírez, Hugo, Macías-Kauffer, Luis R, Jacobo-Albavera, Leonor, López-Contreras, Blanca E, Posadas-Sánchez, Rosalinda, Posadas-Romero, Carlos, Romero-Hidalgo, Sandra, Morán-Ramos, Sofía, Domínguez-Pérez, Mayra, Olivares-Arevalo, Marisol, López-Montoya, Priscilla, Nieto-Guerra, Roberto, Acuña-Alonzo, Víctor, Macín-Pérez, Gastón, Barquera-Lozano, Rodrigo, Del-Río-Navarro, Blanca E, González-González, Israel, Campos-Pérez, Francisco, Gómez-Pérez, Francisco, Valdés, Victor J, Sampieri, Alicia, Reyes-García, Juan G, del C. Carrasco-Portugal, Miriam, Flores-Murrieta, Francisco J, Aguilar-Salinas, Carlos A, Vargas-Alarcón, Gilberto, Shih, Diana, Meikle, Peter J, Calkin, Anna C, Drew, Brian G, Vaca, Luis, Lusis, Aldons J, Huertas-Vazquez, Adriana, Villarreal-Molina, Teresa, and Canizales-Quinteros, Samuel

Subjects
Biomedical and Clinical Sciences, Cardiovascular Medicine and Haematology, Clinical Sciences, Heart Disease - Coronary Heart Disease, Human Genome, Heart Disease, Minority Health, Genetics, Atherosclerosis, Biotechnology, Clinical Research, Prevention, Cardiovascular, 2.1 Biological and endogenous factors, Adult, Age of Onset, Animals, Biomarkers, Case-Control Studies, Child, Cholesterol, HDL, Coronary Artery Disease, Disease Models, Animal, Female, Genetic Predisposition to Disease, Genome-Wide Association Study, HEK293 Cells, Heart Disease Risk Factors, Humans, Hyperlipoproteinemia Type II, Male, Mendelian Randomization Analysis, Mexico, Mice, Middle Aged, Nucleotide Transport Proteins, Phenotype, Polymorphism, Single Nucleotide, Risk Assessment, cholesterol, coronary artery disease, dyslipidemias, genetics, genome, Cardiorespiratory Medicine and Haematology, Cardiovascular System & Hematology, Cardiovascular medicine and haematology, Clinical sciences
Abstract

ObjectiveLow HDL-C (high-density lipoprotein cholesterol) is the most frequent dyslipidemia in Mexicans, but few studies have examined the underlying genetic basis. Our purpose was to identify genetic variants associated with HDL-C levels and cardiovascular risk in the Mexican population.Approach and resultsA genome-wide association studies for HDL-C levels in 2335 Mexicans, identified four loci associated with genome-wide significance: CETP, ABCA1, LIPC, and SIDT2. The SIDT2 missense Val636Ile variant was associated with HDL-C levels and was replicated in 3 independent cohorts (P=5.9×10−18 in the conjoint analysis). The SIDT2/Val636Ile variant is more frequent in Native American and derived populations than in other ethnic groups. This variant was also associated with increased ApoA1 and glycerophospholipid serum levels, decreased LDL-C (low-density lipoprotein cholesterol) and ApoB levels, and a lower risk of premature CAD. Because SIDT2 was previously identified as a protein involved in sterol transport, we tested whether the SIDT2/Ile636 protein affected this function using an in vitro site-directed mutagenesis approach. The SIDT2/Ile636 protein showed increased uptake of the cholesterol analog dehydroergosterol, suggesting this variant affects function. Finally, liver transcriptome data from humans and the Hybrid Mouse Diversity Panel are consistent with the involvement of SIDT2 in lipid and lipoprotein metabolism.ConclusionsThis is the first genome-wide association study for HDL-C levels seeking associations with coronary artery disease in the Mexican population. Our findings provide new insight into the genetic architecture of HDL-C and highlight SIDT2 as a new player in cholesterol and lipoprotein metabolism in humans.

Published
2021

128. Conformally invariant proper time with general non-metricity

Author

Delhom, Adria, Lobo, Iarley P., Olmo, Gonzalo J., and Romero, Carlos

Subjects
General Relativity and Quantum Cosmology
Abstract

We show that the definition of proper time for Weyl-invariant space-times given by Perlick naturally extends to spaces with arbitrary non-metricity. We then discuss the relation between this generalized proper time and the Ehlers-Pirani-Schild definition of time when there is arbitrary non-metricity. Then we show how this generalized proper time suffers from a second clock effect. Assuming that muons are a device to measure this proper time, we constrain the non-metricity tensor on Earth's surface and then elaborate on the feasibility of such assumption., Comment: 12, 2 figures, updated to match published version

Published
2020
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141. Search for light mediators in the low-energy data of the CONNIE reactor neutrino experiment

Author

Aguilar-Arevalo, Alexis, Bertou, Xavier, Bonifazi, Carla, Cancelo, Gustavo, Cervantes-Vergara, Brenda A., Chavez, Claudio, D'Olivo, Juan C., Anjos, João C. dos, Estrada, Juan, Neto, Aldo R. Fernandes, Fernandez-Moroni, Guillermo, Foguel, Ana, Ford, Richard, Izraelevitch, Federico, Kilminster, Ben, Lima Jr, H. P., Makler, Martin, Molina, Jorge, Mota, Philipe, Nasteva, Irina, Paolini, Eduardo, Romero, Carlos, Sarkis, Youssef, Sofo-Haro, Miguel, Tiffenberg, Javier, and Torres, Christian

Subjects
High Energy Physics - Experiment, Physics - Instrumentation and Detectors
Abstract

The CONNIE experiment is located at a distance of 30 m from the core of a commercial nuclear reactor, and has collected a 3.7 kg-day exposure using a CCD detector array sensitive to an $\sim$1 keV threshold for the study of coherent neutrino-nucleus elastic scattering. Here we demonstrate the potential of this low-energy neutrino experiment as a probe for physics Beyond the Standard Model, by using the recently published results to constrain two simplified extensions of the Standard Model with light mediators. We compare the new limits with those obtained for the same models using neutrinos from the Spallation Neutron Source. Our new constraints represent the best limits for these simplified models among the experiments searching for CE$\nu$NS for a light vector mediator with mass $M_{Z^{\prime}}<$ 10 MeV, and for a light scalar mediator with mass $M_{\phi}<$ 30 MeV. These results constitute the first use of the CONNIE data as a probe for physics Beyond the Standard Model., Comment: Accepted for publication in JHEP

Published
2019
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144. A generalized Weyl structure with arbitrary non-metricity

Author

Delhom, Adria, Lobo, Iarley P., Olmo, Gonzalo J., and Romero, Carlos

Subjects
General Relativity and Quantum Cosmology, High Energy Physics - Theory
Abstract

A Weyl structure is usually defined by an equivalence class of pairs $({\bf g}, \boldsymbol{\omega})$ related by Weyl transformations, which preserve the relation $\nabla {\bf g}=\boldsymbol{\omega}\otimes{\bf g}$, where ${\bf g}$ and $\boldsymbol{\omega}$ denote the metric tensor and a 1-form field. An equivalent way of defining such a structure is as an equivalence class of conformally related metrics with a unique affine connection $\Gamma_{\boldsymbol{\omega}}$, which is invariant under Weyl transformations. In a standard Weyl structure, this unique connection is assumed to be torsion-free and have vectorial non-metricity. This second view allows us to present two different generalizations of standard Weyl structures. The first one relies on conformal symmetry while allowing for a general non-metricity tensor, and the other comes from extending the symmetry to arbitrary (disformal) transformations of the metric., Comment: 9 pages, updated to match published version, some discussions extended

Published
2019
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145. Exploring low-energy neutrino physics with the Coherent Neutrino Nucleus Interaction Experiment (CONNIE)

Author

Aguilar-Arevalo, Alexis, Bertou, Xavier, Bonifazi, Carla, Cancelo, Gustavo, Castañeda, Alejandro, Vergara, Brenda Cervantes, Chavez, Claudio, D'Olivo, Juan C., Anjos, João C. dos, Estrada, Juan, Neto, Aldo R. Fernandes, Moroni, Guillermo Fernandez, Foguel, Ana, Ford, Richard, Cuevas, Juan Gonzalez, Hernández, Pamela, Hernandez, Susana, Izraelevitch, Federico, Kavner, Alexander R., Kilminster, Ben, Kuk, Kevin, Lima Jr, H. P., Makler, Martin, Molina, Jorge, Mota, Philipe, Nasteva, Irina, Paolini, Eduardo E., Romero, Carlos, Sarkis, Y., Haro, Miguel Sofo, Souza, Iruatã M. S., Tiffenberg, Javier, and Wagner, Stefan

Subjects
Physics - Instrumentation and Detectors, Astrophysics - Instrumentation and Methods for Astrophysics, High Energy Physics - Experiment
Abstract

The Coherent Neutrino-Nucleus Interaction Experiment (CONNIE) uses low-noise fully depleted charge-coupled devices (CCDs) with the goal of measuring low-energy recoils from coherent elastic scattering (CE$\nu$NS) of reactor antineutrinos with silicon nuclei and testing nonstandard neutrino interactions (NSI). We report here the first results of the detector array deployed in 2016, considering an active mass 47.6 g (8 CCDs), which is operating at a distance of 30 m from the core of the Angra 2 nuclear reactor, with a thermal power of 3.8 GW. A search for neutrino events is performed by comparing data collected with reactor on (2.1 kg-day) and reactor off (1.6 kg-day). The results show no excess in the reactor-on data, reaching the world record sensitivity down to recoil energies of about 1 keV (0.1 keV electron-equivalent). A 95% confidence level limit for new physics is established at an event rate of 40 times the one expected from the standard model at this energy scale. The results presented here provide a new window to low-energy neutrino physics, allowing one to explore for the first time the energies accessible through the low threshold of CCDs. They will lead to new constrains on NSI from the CE$\nu$NS of antineutrinos from nuclear reactors., Comment: Updated to match the version accepted for publication in Physical Review D

Published
2019
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148. Translation, Factor Structure and Reliability of the Future Time Perspective Scale for Adolescents and Young Adults (FTPS-AYA) in a Mexican Sample/Traducción, Estructura Factorial y Confiabilidad de la Escala de Perspectiva del Tiempo Futuro para Adolescentes y Adultos Jóvenes (FTPS-AYA) en una Muestra Mexicana

Author

Osorio-Guzman, Maricela, Prado-Romero, Carlos, Ruiz-Mendoza, Centeotl, Nino- Higuera, Rosario Isabel, Sommantico, Massimiliano, and Parrello, Santa

Published
2022
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