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Leber's optic neuropathy is a maternally inherited disease. Its transmission does not correspond to Mendelian principles and two hypothesis about the role of cytoplasmic transmission are discussed. The role of a virus or a mutation mitochondrial DNA, maternally transmitted, are possible. However if not definite conclusion can be, actually, certified, there is a good hope to find a solution for this disease, in a near future.

From the study of twelve of Fundus Flavimaculatus and after recording the main characteristics of this disease the authors try to distinguish the "classical juvenile" form of Fundus Flavimaculatus form the "tardy" form of Fundus Flavimaculatus. This last one would affect the adult and have a better prognosis.

From series of clinical cases, the authors expose how ERG is an essential element for the diagnosis of cone dysfunction with or without macular involvement. They show that to obtain an accurate diagnosis, precise proceedings must be chosen, using stimulation technics correctly selected. They study the advantage of focal or wide stimulations, of the level of the intensity of the stimulation and of the different colored filters. They propose a proceeding for adults examination. For young children, they discuss the advantages and limits of a particular proceeding.

In 1801 at the cemetery in Vienna, Austria, the skull of W.A. Mozart was exhumed (La Chronique Médicale, 13 (1906) 423), and now it has been examined for identification. The osteometrical and osteological findings correspond with the available data of W.A. Mozart. Superimposition gives evidence that craniofacial distinctiveness of the cranium is consistent with the portrait. Additional individual particularities caused by the premature synostosis of the metopic suture (PSMS) and a bone lesion are described.

Many features allow to assert that Stargardt disease and fundus flavimaculatus are the one and same disease: clinically and functionally, macular and perimacular lesions present an absolute identity "Pure" fundus flavimaculatus does not exist the two affections can be found in a same pedigree (5 cases) a patient presenting one of these diseases can develop a more complete form (7 cases). The disease is usually and more often inherited as an autosomal recessive than an autosomal dominant fashion (5 cases out of 96 genealogies) with variable expressivity particularly for "flavimacular" lesions. The frequency of the disease is 1/6,670 inhabitants. There are two genes or more in charge of the disease.