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101. Safe removal of the radial artery for myocardial revascularization: a Doppler study to prevent ischemic complications to the hand

Author

Roberto Flore, Angela Favuzzi, Eric Manasse, Paolo Pola, Michele Serricchio, and Gian Federico Possati

Subjects
Pulmonary and Respiratory Medicine, Adult, Male, medicine.medical_specialty, Ischemia, Subclavian Artery, Hemodynamics, Collateral Circulation, Arterial Occlusive Diseases, Constriction, Pathologic, Allen's test, Ulnar Artery, medicine.artery, Internal medicine, Preoperative Care, medicine, Humans, Derivation, Radial artery, Coronary Artery Bypass, Subclavian artery, Ulnar artery, Vascular Patency, Aged, business.industry, Contraindications, Patient Selection, Ultrasonography, Doppler, Middle Aged, medicine.disease, Hand, Surgery, Stenosis, Regional Blood Flow, Radial Artery, Cardiology, Female, Safety, Cardiology and Cardiovascular Medicine, business, Blood Flow Velocity, Follow-Up Studies
Abstract

Radial artery harvesting has recently been reintroduced for myocardial revascularization. Harvesting the radial artery may jeopardize the vascularization of the hand; cautious selection of candidates must therefore be pursued. The study involved 188 consecutive patients. We verified the patency of the upper limb's arteries and the adequacy of the ulnar supply by static and dynamic Doppler evaluations. The use of the radial artery was contraindicated in 14 cases (three for stenosis of the subclavian artery and 11 for inadequate collateralization). One hundred patients were operated on with the radial artery used as a graft; the remaining 74 patients had a different conduit placed. The vascularization of the hand was restudied within 10 days in all patients who underwent operation; in 63 patients, it was studied again at 1 year. The early Doppler examination showed significant increase in blood flow velocities in the ulnar artery, with a flow redistribution in the common digital palmar arteries (decreased in the first and increased in the second and the third). The late Doppler examination showed superimposable findings. No local ischemic complications were observed. We conclude that Doppler study is a useful tool in preoperative screening of candidates for radial artery harvesting for myocardial revascularization. (J THORAC CARDIOVASC SURG 1996;112:737-44)

Published
1996

102. Letters to the Editor

Author

Paolo Pola, Antonio Gasbarrini, Enrico Celestino Nista, Maurizio Gabrielli, Angelo Santoliquido, and Marcello Candelli

Subjects
medicine.medical_specialty, business.industry, MEDLINE, Retrospective cohort study, Migraine Disorders, Seroepidemiologic Studies, medicine.disease, Chronic disease, Neurology, Migraine, Internal medicine, Physical therapy, Medicine, Seroprevalence, Neurology (clinical), business
Published
2004

103. Subject Index Vol. 18, 2004

Author

Roger Bullock, Ka Sing Wong, Karine Pérès, Hannu Puolijoki, Timothy Kwok, Pascale Barberger-Gateau, Anja Kerksiek, Klaus von Bergmann, D. Darby, Heike Tost, Brent J. Small, Reijo S. Tilvis, Steve Hughes, Marinella Damian, Stefanie Brassen, Marie Luise Rao, Paolo Pola, Sarah Aldred, Francesca Marchione, Sigurd Johnsen, Lars Bäckman, Laura Fratiglioni, P. Maruff, Jean-François Dartigues, J.C. Mourik, Heike Kölsch, Reinhard Heun, Caterina Calderaro, Pierangelo Papaleo, Thomas A. Crum, Warren W. Barker, Christian Spell, H.J. Duivenvoorden, Wolfgang Maier, M.F. Niermeijer, Angela Di Giorgio, Ekaterina Rogaeva, Tero Vahlberg, Raimo E. Isoaho, Eric Wong, Antoine Regnault, Roberto Bernabei, Giovanni Antonini, Ranjan Duara, Hsiu-Chih Liu, Francesco E. Pontieri, Georg Adler, Ker-Neng Lin, Minna Löppönen, Vincent Mok, Timo I. Takala, Cheryl A. Luis, Sirkka-Liisa Kivelä, Timo E. Strandberg, Andrea Flex, Helmut Sies, Toshitaka Kawarai, Sandra S. M. Chan, Wolfgang Weber-Fahr, Brunella Caronti, Dieter Lütjohann, Wai Kwong Tang, Umberto Senin, Saila M. Loikas, Kuan-Ying Wu, Kaisu H. Pitkälä, Gabor S. Ungvari, Erika J. Laukka, Eleonora Gaetani, J. C. van Swieten, Sari Jones, Jouko V. Laurila, S.M. Rosso, A. Tibben, Ian Hindmarch, Javier Llorca, Kerttu M. Irjala, Hyman Engelberg, Ahmadou Alioum, Misha Nikulin, Frank Hentschel, Ercole Brunetti, J. Weaver-Cargin, Onofre Combarros, Jon Currie, Ismo Räihä, Dieter F. Braus, Micaela Sepe-Monti, Helen R. Griffiths, David A. Loewenstein, Paolo Tisei, Roberta Cecchetti, Jon Infante, C. Masters, Steffen Moritz, Roberto Pola, A. Collie, Peter St George-Hyslop, Paola Mattioli, Michele Serricchio, Wilhelm Stahl, Franco Giubilei, Patrizia Mecocci, M. Cristina Polidori, Colette Fabrigoule, Rung-Ching Tsai, Helen F.K. Chiu, José Berciano, and Anna S. Proia

Subjects
Psychiatry and Mental health, Index (economics), Cognitive Neuroscience, Subject (documents), Geriatrics and Gerontology, Psychology, Developmental psychology
Published
2004

104. Contents Vol. 18, 2004

Author

C. Masters, Roberto Pola, Christian Spell, H.J. Duivenvoorden, Paola Mattioli, Laura Fratiglioni, Kuan-Ying Wu, Erika J. Laukka, Franco Giubilei, Rung-Ching Tsai, J. C. van Swieten, Helen F.K. Chiu, Warren W. Barker, Thomas A. Crum, Timothy Kwok, Pascale Barberger-Gateau, Peter St George-Hyslop, Michele Serricchio, Steve Hughes, Wilhelm Stahl, Gabor S. Ungvari, Sarah Aldred, Patrizia Mecocci, Reinhard Heun, Steffen Moritz, Ker-Neng Lin, Toshitaka Kawarai, Brunella Caronti, Stefanie Brassen, Andrea Flex, Eric Wong, Wolfgang Weber-Fahr, A. Collie, Georg Adler, Ka Sing Wong, Hsiu-Chih Liu, Helmut Sies, Vincent Mok, Roger Bullock, Francesca Marchione, Umberto Senin, J.C. Mourik, Brent J. Small, Pierangelo Papaleo, Colette Fabrigoule, Sigurd Johnsen, Angela Di Giorgio, M.F. Niermeijer, Jouko V. Laurila, Tero Vahlberg, Marie Luise Rao, Antoine Regnault, Giovanni Antonini, Heike Tost, Ian Hindmarch, Klaus von Bergmann, Timo I. Takala, P. Maruff, Marinella Damian, Jean-François Dartigues, Paolo Tisei, Heike Kölsch, D. Darby, Ercole Brunetti, M. Cristina Polidori, Onofre Combarros, Wai Kwong Tang, Reijo S. Tilvis, Sirkka-Liisa Kivelä, Sari Jones, Saila M. Loikas, Kaisu H. Pitkälä, Timo E. Strandberg, S.M. Rosso, Kerttu M. Irjala, Hyman Engelberg, J. Weaver-Cargin, Minna Löppönen, Ahmadou Alioum, Jon Currie, Misha Nikulin, Sandra S. M. Chan, Ismo Räihä, Dieter F. Braus, Lars Bäckman, A. Tibben, Frank Hentschel, Karine Pérès, Francesco E. Pontieri, Hannu Puolijoki, Dieter Lütjohann, Roberto Bernabei, Eleonora Gaetani, Javier Llorca, Ekaterina Rogaeva, Cheryl A. Luis, Roberta Cecchetti, Jon Infante, Caterina Calderaro, Ranjan Duara, Anja Kerksiek, Paolo Pola, Wolfgang Maier, Raimo E. Isoaho, José Berciano, Anna S. Proia, Micaela Sepe-Monti, Helen R. Griffiths, and David A. Loewenstein

Subjects
Psychiatry and Mental health, Cognitive Neuroscience, Geriatrics and Gerontology
Published
2004

105. Hyperhomocysteinemia, Helicobacter pylori and atrophic gastritis

Author

Giovanni Gasbarrini, Barbara De Pascalis, Filippo Cremonini, Maurizio Gabrielli, Vernoica Ojetti, Luca Santarelli, Antonio Gasbarrini, Paolo Pola, and Ascanio Tridente

Subjects
medicine.medical_specialty, Hyperhomocysteinemia, Hepatology, biology, business.industry, Atrophic gastritis, Gastroenterology, Helicobacter pylori, medicine.disease, biology.organism_classification, Internal medicine, Medicine, business
Published
2003

106. Evaluation of the human haematopoietic stem cell potential in liver regeneration: Analysis of homing and differentiation patterns in a nod/scid mouse model

Author

Sergio Rutella, Luca Pierelli, Alessandro Gasbarrini, Anna Chiara Piscaglia, C. Di Campli, Gianfranco Zannoni, G. Gasbarrini, Paolo Pola, G. Bonanno, Giuseppe Leone, A. Mariotti, and Fabio Maria Vecchio

Subjects
Haematopoiesis, Hepatology, Nod, Biology, Stem cell, Scid mouse model, Liver regeneration, Cell biology, Homing (hematopoietic)
Published
2003

107. Helicobacter pylori , CagA-Positive Strains, and Ischemic Stroke

Author

Antonio Gasbarrini, Maurizio Gabrielli, and Paolo Pola

Subjects
medicine.medical_specialty, Helicobacter pylori infection, Pathology, Settore MED/12 - GASTROENTEROLOGIA, Comorbidity, Disease, Gastroenterology, Helicobacter Infections, Bacterial Proteins, Risk Factors, Polymorphism (computer science), Internal medicine, ischemic stroke, Prevalence, medicine, Humans, Cytotoxic T cell, CagA, Genetic Predisposition to Disease, Stroke, Advanced and Specialized Nursing, Antigens, Bacterial, Polymorphism, Genetic, Helicobacter pylori, Virulence, biology, business.industry, bacterial infections and mycoses, biology.organism_classification, medicine.disease, Causality, Chronic Disease, Ischemic stroke, Neurology (clinical), Cardiology and Cardiovascular Medicine, business
Abstract

To the Editor: In their interesting study, Heuschmann et al1 showed the chronic Helicobacter pylori infection to be associated with a higher risk of stroke caused by small-artery occlusion, a subtype of ischemic stroke also sharing pathomechanisms with atherosclerotic disease. A similar trend was demonstrated for stroke caused by large-artery atherosclerosis, although this trend was not statistically significant. We would like to make some comments on it. Several studies have shown that the clinical outcome of H pylori infection is strictly related to the genetic polymorphism of both the bacterium2 and the host.3 In fact, recent findings have demonstrated H pylori infection to be only weakly associated with ischemic heart disease in multivariate analysis. On the other hand, the more cytotoxic H pylori strains, bearing the cytotoxin-associated gene A (CagA), were highly prevalent in patients with ischemic heart disease.4 On the basis of these observations, it could be interesting to investigate the prevalence of CagA-positive strains of the bacterium in patients with …

Published
2002

108. Iloprost for Age-Related Macular Degeneration: Long-Term Efficacy Evaluation

Author

Roberto Pola, Eleonora Gaetani, Andrea Flex, and Paolo Pola

Subjects
medicine.medical_specialty, Visual acuity, business.industry, Treatment outcome, Macular degeneration, medicine.disease, Surgery, Term (time), Vasodilator agents, Ophthalmology, Age related, medicine, Geriatrics and Gerontology, medicine.symptom, business, Iloprost, medicine.drug
Published
2002

109. Re: 'Chronic Helicobacter Pylori Infection and Migraine: A Case‐Control Study' (Pinessi L, Savi L, Pellicano R, et al. Headache . 2000;40:836‐839)

Author

Paolo Pola, Antonio Gasbarrini, Giovanni Gasbarrini, M Giacovazzo, Marcello Candelli, Maurizio Gabrielli, and G Fiore

Subjects
Helicobacter pylori infection, medicine.medical_specialty, Pathology, Migraine Disorders, MEDLINE, Gastroenterology, Helicobacter Infections, Internal medicine, Humans, Medicine, Helicobacter pylori, biology, business.industry, Incidence, Incidence (epidemiology), Case-control study, biology.organism_classification, medicine.disease, Chronic disease, Neurology, Migraine, Case-Control Studies, Chronic Disease, Neurology (clinical), business
Published
2002

110. New prospects for the treatment of Raynaud's phenomenon using a serotoninergic S2 receptor antagonist (ketanserin) and stable derivatives of prostacyclin

Author

Angela Favuzzi, Paolo Pola, Michele Serricchio, P. Tondi, and Laura Gerardino

Subjects
Adult, Male, 030213 general clinical medicine, medicine.medical_specialty, Ketanserin, medicine.drug_class, medicine.medical_treatment, Prostacyclin, 030204 cardiovascular system & hematology, Serotonergic, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, Prostaglandins, Synthetic, medicine, Humans, Photoplethysmography, Aged, Chemotherapy, business.industry, Antagonist, Raynaud Disease, Middle Aged, Receptor antagonist, Epoprostenol, Endocrinology, Treatment Outcome, cardiovascular system, Pulse oxymetry, Transcutaneous pulse oximetry, Drug Therapy, Combination, Female, Cardiology and Cardiovascular Medicine, business, Blood Gas Monitoring, Transcutaneous, medicine.drug
Abstract

The authors propose a promising new therapy for the treatment of Raynaud's phenomenon, with parenteral prostacyclin (carbaprostacycline) and a serotonergic S2-receptor antagonist (ketanserin) given orally. They studied 31 patients, 22 treated with ketanserin and carbaprostacycline, 9 with carbaprostacycline alone. Both groups demonstrated successful results and a significant improvement in measurements performed by photoplethysmography and transcutaneous pulse oxymetry.

Published
1993

111. How to Reduce the Ischemic Brain Damage Secondary to Severe Head Injury?

Author

Paolo Pola, Giulio Maira, P. Amante, Carmelo Anile, A. Dal Lago, F. Della Corte, Annunziato Mangiola, P. Palma, and A. Rinaldi

Subjects
medicine.medical_specialty, Severe head injury, business.industry, medicine.medical_treatment, Glasgow Outcome Scale, Head injury, Ischemia, Brain damage, medicine.disease, Internal medicine, medicine, Cardiology, Decompressive craniectomy, Cerebral perfusion pressure, medicine.symptom, business, Cause of death
Abstract

Head injury represents the cause of injury deaths in 50–70% of cases and is the main cause of death in the group under 20 years of age. Brain sequelae are often so severe as to hinder a satisfactory social reintegration. Prevention and control of the extension of the secondary cerebral lesions are important. Ischaemia has been recognized as the common final pathway in post-traumatic brain damage and seems to be mainly due to acute intracranial hypertension and decreased cerebral perfusion pressure (CPP) [3].

Published
1993

112. Hepatic mitochondrial beta-oxidation assessment in healthy subjects by sodium 13C-octanoate breath test

Author

Maurizio Gabrielli, Antonio Gasbarrini, Maria Assunta Zocco, Luca Miele, Antonino De Lorenzo, Paolo Pola, Alessandro Armuzzi, E. Carloni, Giovanni Gasbarrini, and Antonio Grieco

Subjects
Breath test, medicine.medical_specialty, Hepatology, medicine.diagnostic_test, business.industry, Settore MED/12 - GASTROENTEROLOGIA, Sodium, Gastroenterology, Healthy subjects, chemistry.chemical_element, Endocrinology, N/A, chemistry, Internal medicine, medicine, business, Beta oxidation
Published
2000

113. [368] USE OF G-CSF DURING ACUTE ON CHRONIC LIVER FAILURE: CLINICAL AND BIOCHEMICAL SAFETY PROFILE

Author

Marialuisa Novi, Alessandro Gasbarrini, Maria Assunta Zocco, G. Gasbarrini, E. Rinninella, M.E. Ainora, C. Di Campli, Giuseppe Leone, G. Di Gioacchino, Paolo Pola, Sergio Rutella, and G.L. Rapaccini

Subjects
Safety profile, medicine.medical_specialty, Hepatology, business.industry, Internal medicine, Medicine, Acute on chronic liver failure, business, Gastroenterology
Published
2007

114. Use of G-CSF during acute on chronic liver failure: Clinical and biochemical safety profile

Author

Maria Assunta Zocco, G. Di Gioacchino, G. Gasbarrini, C. Di Campli, Ludovico Abenavoli, Alessandro Gasbarrini, Marialuisa Novi, Luca Miele, Alessandra Forgione, R. Sergio, A. Grieco, Paolo Pola, Giovanni Addolorato, G.L. Rapaccini, M.E. Ainora, and Giuseppe Leone

Subjects
medicine.medical_specialty, Safety profile, N/A, Hepatology, business.industry, Settore MED/12 - GASTROENTEROLOGIA, Internal medicine, Gastroenterology, medicine, Acute on chronic liver failure, business
Published
2006

115. Should bone marrow aspirate be performed before using G-CSF in patients with acute on chronic liver failure?

Author

Giovanni Addolorato, M.E. Ainora, C. Di Campli, Paolo Pola, N. Piccirillo, G. Di Gioacchino, Luca Miele, A. Grieco, Alessandra Forgione, Ludovico Abenavoli, Alessandro Gasbarrini, G.L. Rapaccini, Maria Assunta Zocco, Giuseppe Leone, G. Gasbarrini, and Marialuisa Novi

Subjects
medicine.medical_specialty, Bone marrow aspirate, Hepatology, business.industry, Internal medicine, Gastroenterology, Medicine, In patient, Acute on chronic liver failure, business
Published
2006

119. High Rate of Helicobacter pylori Re-Infection in Patients Affected by Type 1 Diabetes

Author

Giovanni Gasbarrini, Alessio Migneco, Dario Pitocco, Veronica Ojetti, Silvio Danese, Antonio Gasbarrini, Andrea Lupascu, F. Bartolozzi, Paolo Pola, Giovanni Ghirlanda, Ojetti, V, Pitocco, D, Bartolozzi, F, Danese, S, Migneco, A, Lupascu, A, Pola, P, Ghirlanda, G, Gasbarrini, G, and Gasbarrini, A

Subjects
medicine.medical_specialty, Endocrinology, Diabetes and Metabolism, Gastroenterology, Helicobacter Infections, Recurrence, Internal medicine, Diabetes mellitus, Internal Medicine, medicine, Humans, In patient, Advanced and Specialized Nursing, High rate, Type 1 diabetes, Helicobacter pylori, biology, business.industry, Incidence (epidemiology), medicine.disease, biology.organism_classification, Control subjects, Surgery, Diabetes Mellitus, Type 1, business, Re infection
Abstract

Patients affected by type 1 diabetes appear to be more prone to infection than healthy subjects (1). Recently, it has been shown that Helicobacter pylori ( H. pylori ) infection is common in type 1 diabetes (2) and that the use of a standard antibiotic therapy obtains a significantly lower eradication rate than in non–insulin-dependent diabetic subjects (3,4). Our aim was to assess the incidence of H. pylori re-infection after a successful therapy in type 1 diabetic patients. A total of 74 subjects previously infected by H. pylori were enrolled, including 34 type 1 diabetic subjects (16 women and 18 men, 42 ± 9 years of age) and 40 nondiabetic control subjects (17 women and 23 …

Published
2002

120. 6 P Venous thromboembolism, hyperhomocysteinemia and silent coeliac disease: A case report

Author

M.C. Andrisani, Lucia Fini, Maurizio Gabrielli, Angelo Santoliquido, Paolo Pola, Luca Santarelli, G. Gasbarrini, and Alessandro Gasbarrini

Subjects
medicine.medical_specialty, Hyperhomocysteinemia, Hepatology, business.industry, Internal medicine, Gastroenterology, medicine, medicine.disease, business, Venous thromboembolism, Coeliac disease
Published
2002

121. 5 OP Association between migraine and coeliac disease

Author

Alessandro Gasbarrini, G Fiore, G. Gasbarrini, M.E. De Leo, G. Addolarato, Immacolata A. Cazzato, Marcello Candelli, C. Padalino, Maurizio Gabrielli, Mario Giacovazzo, Paolo Pola, Lucia Fini, and E.C. Nista

Subjects
medicine.medical_specialty, Hepatology, Migraine, business.industry, Internal medicine, Gastroenterology, medicine, medicine.disease, business, Coeliac disease
Published
2002

123. Migraine: First symptom of cryptic coeliac disease?

Author

Veronica Ojetti, Silvio Danese, Paolo Pola, Marcello Candelli, Alessandro Gasbarrini, Maurizio Gabrielli, G. Di Campli, G. Gasbarrini, V. Basile, Filippo Cremonini, Mario Giacovazzo, M.E. De Leo, and G. Padalino

Subjects
medicine.medical_specialty, Hepatology, Migraine, business.industry, Gastroenterology, medicine, medicine.disease, business, Dermatology, Coeliac disease
Published
2001

124. Early gastric mucosal lesions in helicobacter pylori infected mongolian gerbils

Author

Michael S. Osato, David Y. Graham, Kevin Otten, Giovanni Gasbarrini, Paolo Pola, Francesco Franceschi, Antonio Gasbarrini, Robert M. Genta, and Antonia R. Sepulveda

Subjects
Pathology, medicine.medical_specialty, Hepatology, biology, business.industry, Mucosal lesions, Gastroenterology, medicine, Helicobacter pylori, business, biology.organism_classification
Published
2001

125. Anti-CagA antibodies cross-react with vascular antigens

Author

Francesco Franceschi, Alessandro Gasbarrini, David Y. Graham, G. Gasbarrini, Robert M. Genta, Antonia R. Sepulveda, and Paolo Pola

Subjects
Hepatology, biology, Antigen, business.industry, Immunology, Gastroenterology, biology.protein, CagA, Medicine, Antibody, business
Published
2001

126. Production of the angiogenic factor platelet-derived endothelial cell growth factor in colorectal adenomas and adenocarcinomas

Author

Giovanni Gasbarrini, Paolo Pola, Antonio Gasbarrini, Francesco Franceschi, Robert M. Gents, and Antonia R. Sepulveda

Subjects
Oncology, medicine.medical_specialty, Hepatology, biology, business.industry, Internal medicine, VEGF receptors, Platelet-Derived Endothelial Cell Growth Factor, Gastroenterology, Cancer research, medicine, biology.protein, business
Published
2001

127. Infection by CAG-A positive strains of h. pylori are highly prevalent in patients with ischemic stroke

Author

Alessandro Gasbarrini, Luca Santarelli, Marcello Candelli, G. Gasbarrini, Maurizio Gabrielli, Angelo Santoliquido, Michele Serricchio, Filippo Cremonini, Paolo Pola, Paolo Tondi, R.L. Grillo, F. Bartolozzi, and V. Cicconi

Subjects
medicine.medical_specialty, Hepatology, business.industry, Internal medicine, Ischemic stroke, Gastroenterology, medicine, In patient, business
Published
2001

128. Metolazone-induced cholestatic liver disease

Author

Antonio Gasbarrini, R. Fiore, Andrea Flex, Eleonora Gaetani, Paolo Pola, Maurizio Gabrielli, and Angelo Santoliquido

Subjects
medicine.medical_specialty, cholestatic, Hepatology, business.industry, Settore MED/12 - GASTROENTEROLOGIA, Gastroenterology, metolazone, chemistry.chemical_compound, chemistry, Internal medicine, medicine, Metolazone, Cholestatic liver disease, business
Published
2001

129. Gender affects 13C-Ketoisocaproic breath test for liver mithocondrial function

Author

Paolo Pola, Luca Miele, E.C. Nista, A. Armuzzi, Marcello Candelli, Maria Assunta Zocco, G. Gasbarrini, A. Grieco, and Alessandro Gasbarrini

Subjects
Breath test, medicine.medical_specialty, Hepatology, medicine.diagnostic_test, business.industry, Internal medicine, medicine, Cardiology, Function (mathematics), business
Published
2001

131. High prevalence of celiac disease in Migraine

Author

Filippo Cremonini, Maurizio Gabrielli, Veronica Ojetti, Paolo Pola, Marcello Candelli, Giovanni Gasbarrini, Silvio Danese, C. Padalino, Antonio Gasbarrini, Giuseppe Fiore, Mario Giacovazzo, and Emilia De Leo

Subjects
Pediatrics, medicine.medical_specialty, High prevalence, Hepatology, Migraine, business.industry, Gastroenterology, Medicine, Disease, business, medicine.disease
Published
2001

134. 13C urea breath test for predicting resistance to therapy in Helicobacter pylori infection

Author

S. De Caro, Paolo Pola, Luca Santarelli, Filippo Cremonini, S. Colasanti, Silvio Danese, Maurizio Gabrielli, Giovanni Gasbarrini, F. Bartolozzi, C. Padalino, Antonio Gasbarrini, A. Armuzzi, and Maria Assunta Zocco

Subjects
medicine.medical_specialty, Helicobacter pylori infection, Hepatology, business.industry, Internal medicine, Gastroenterology, medicine, business, 13C urea breath test
Published
2000

135. Impact of Lactobacillus Gg supplementation on anti-H. Pylori therapy-related side effect: A randomized placebo-controlled study

Author

S. Colasanti, A. Armuzzi, Maria Assunta Zocco, F. Bartolozzi, Antonio Gasbarrini, E. Carloni, Paolo Pola, Filippo Canducci, Marcello Candelli, Giovanni Gasbarrini, and Filippo Cremonini

Subjects
medicine.medical_specialty, Lactobacillus GG, Therapy related, Hepatology, Side effect, business.industry, Internal medicine, Gastroenterology, medicine, Placebo-controlled study, business
Published
2000

136. Helicobacter pylori infection and multiple myeloma: Is there a link?

Author

Antonio Gasbarrini, Giovanni Gasbarrini, Marcello Candelli, Silvio Danese, Valerio De Stefano, Filippo Cremonini, Alessandro Armuzzi, Giuseppe Leone, Paolo Pola, and Antonella Di Mario

Subjects
Helicobacter pylori infection, Hepatology, business.industry, Immunology, Gastroenterology, Medicine, business, medicine.disease, Multiple myeloma
Published
2000

137. C-reactive protein and coronary disease

Author

Filippo Cremonini, Paolo Pola, and Antonio Gasbarrini

Subjects
Helicobacter pylori, biology, business.industry, C-reactive protein, Coronary Disease, Chlamydia Infections, Chlamydophila pneumoniae, Pharmacology, Coronary disease, Antibodies, Bacterial, Helicobacter Infections, C-Reactive Protein, Risk Factors, Acute Disease, biology.protein, Humans, Medicine, Cardiology and Cardiovascular Medicine, business, Biomarkers
Published
1999

138. Benefical effects of Helicobacter pylori eradication on migraine

Author

Marcello Candelli, Maurizio Gabrielli, Mario Giacovazzo, G. Gasbarrini, Paolo Pola, A. De Luca, Veronica Ojetti, G Fiore, E Sanz Torre, Francesco Franceschi, I Massari, and Alessandro Gasbarrini

Subjects
medicine.medical_specialty, Hepatology, biology, business.industry, Gastroenterology, Helicobacter pylori, medicine.disease, biology.organism_classification, Microbiology, Migraine, Internal medicine, Medicine, business
Published
1998

139. Helicobacter pylori infection in primary headache

Author

Alessandro Gasbarrini, I Massari, Marcello Candelli, Veronica Ojetti, Paolo Pola, Maurizio Gabrielli, G Fiore, G. Gasbarrini, A. De Luca, Francesco Franceschi, Mario Giacovazzo, and E Sanz Torre

Subjects
medicine.medical_specialty, Helicobacter pylori infection, Primary headache, Hepatology, business.industry, Internal medicine, Gastroenterology, medicine, business
Published
1998

140. Helicobacter pylori eradication ameliorates idiopathic chronic urticaria

Author

I Massari, Veronica Ojetti, Eleonora Nucera, Marcello Candelli, G. Gasbarrini, Maurizio Gabrielli, C. Di Campli, Francesco Franceschi, Paolo Pola, E Sanz Torre, Domenico Schiavino, G Patriarca, Alessandro Gasbarrini, and A. De Luca

Subjects
medicine.medical_specialty, Hepatology, biology, business.industry, Internal medicine, Gastroenterology, medicine, Helicobacter pylori, biology.organism_classification, business, Chronic urticaria
Published
1998

141. Visualization of post-ischemic free radicals formation in livers isolated from rats chronically exposed to ethanol

Author

Giovanni Gasbarrini, Francesco Franceschi, Antonio Gasbarrini, Giovanni Addolorato, Aldo Roda, A. De Luca, Mauro Bernardi, Enrico Roda, Bruno Nardo, G. Vagni, Patrizia Pasini, Mara Simoncini, and Paolo Pola

Subjects
chemistry.chemical_compound, Ethanol, Hepatology, chemistry, Radical, Gastroenterology, Molecular biology
Abstract

L0191 VISUALIZATION OF POST-ISCHEMIC FREE RADICALS FORMATION IN LIVERS ISOLATED FROM RATS CHRONICALLY EXPOSED TO ETHANOL. A Gasbarrini. G Addolorato, M Simoncini, P Pasini, B Nardo, F Franceschi, A De Luca, G Vagni, E Roda, P Pola, M Bemardi, A Roda, G Gasbarrini. Internal Medicine and Gastroenterology Depts, Catholic University of Rome and University of Bologna; Ricerca in Medicina, Bologna; Italy.

Published
1998

142. Regression of autoimmune thrombocytopenic purpura after Helicobacter pylori eradication

Author

Alessandro Gasbarrini, Bianca Maria Ricerca, Francesco Franceschi, Giuseppe Leone, R Tartaglione, Marcello Candelli, G. Gasbarrini, S Storti, A. De Luca, Raffaele Landolfi, Veronica Ojetti, Giovanni Cammarota, and Paolo Pola

Subjects
Hepatology, biology, business.industry, Immunology, Gastroenterology, Autoimmune thrombocytopenic purpura, Medicine, Helicobacter pylori, business, biology.organism_classification
Published
1998

143. Chronic ethanol administration affects oxydative stress due to ischemia/reperfusion in rat liver

Author

G. Gasbarrini, Francesco Franceschi, M Bermardi, G. Vagni, Mara Simoncini, Aldo Roda, Antonio Gasbarrini, A. De Luca, Patrizia Pasini, Bruno Nardo, Giovanni Addolorato, Enrico Roda, and Paolo Pola

Subjects
medicine.medical_specialty, Ethanol, Sucrose, Antioxidant, Hepatology, medicine.medical_treatment, Gastroenterology, Ischemia, Glutathione, Liver transplantation, medicine.disease, chemistry.chemical_compound, Endocrinology, chemistry, Internal medicine, medicine, Adenosine triphosphate, Reperfusion injury
Abstract

Oxydative stress occurs during the reperfusion injury that follows liver transplantation. Ethanol is considered a pro-oxidant agent. In this study, we aimed to assess the effects of chronic ethanol administration on oxydative stress both in basal condition then after reperfusion injury. METHODS: Wistar male rats were exposed to a diet containing sucrose (control) or different amount of ethanol (3, 6, 12, 24 g/d). After 4 weeks, livers were isolated, exposed to warm ischemia for 120 min, then reperfused with an oxygenated medium for 60 min. Adenosine triphosphate (ATP), malondyaldeide (MDA) and reduced gluthatione (GSH) concentration of the liver were determined. RESULTS: in control condition, liver of rats fed with the highest ethanol doses (12 and 24 g/d) showed a significantly lower concentrations of GSH and ATP and a significantly higher concentration of MDA, when compared to the other groups. After 60 min of ischemia, GSH and ATP levels decreased significantly in all groups; newly, however, antioxidant and energy status reached a concentration significantly lower than in controls in livers obtained from rats exposed to 12 and 24 g/ethanol/d. During reperfusion, ATP and GSH recoveedr progressively in all groups at pre-ischemic levels; MDA, however, which increased sharply in all livers, reached significantely greater values in organs from rats treated with 12 and 24 g/ethanol/d. Interestingly, the lowest ethanol concentrations used (3 and 6 g/d) appeared to attenuate MDA tissue generation during reperfusion when compared to livers obtained by control rats. CONCLUSIONS: the chronic administration of high alcohol doses affect liver energy level and antioxidant status and increases the sensitivity of the organs to the oxydative stress caused by ischemia/reperfusion.

Published
1998

144. Role of Helicobacter pylori infection in dyspepsia

Author

Veronica Ojetti, Francesco Franceschi, Giovanni Cammarota, A. De Luca, I Massari, Paolo Pola, Marcello Candelli, G. Gasbarrini, M.E. Lippi, Filippo Canducci, Marcello Anti, Maurizio Gabrielli, Antonio Gasbarrini, Alessandro Armuzzi, C. Di Campli, and E Sanz Torre

Subjects
Helicobacter pylori infection, Hepatology, business.industry, Immunology, Gastroenterology, Medicine, business
Published
1998

145. Helicobacter pylori infection in patients affected by raynaud phenomenon: Beneficial effects of eradication

Author

Paolo Pola, I Massari, Paolo Tondi, Francesco Franceschi, Veronica Ojetti, A. De Luca, Michele Serricchio, G. Gasbarrini, and Alessandro Gasbarrini

Subjects
medicine.medical_specialty, Hepatology, business.industry, Gastroenterology, Lansoprazole, Acute-phase protein, Vasospasm, macromolecular substances, Amoxicillin, medicine.disease, Basal (phylogenetics), Clarithromycin, Internal medicine, medicine, bacteria, Plethysmograph, CagA, business, medicine.drug
Abstract

Recent studies have suggested that H. pylori infection may be associated with primary Raynaud phenomenon (PRP), a functional vascular disorder defined by an intermittent vasospasm of the arterioles of the distal limbs which occurs mostly following exposure to cold or emotional stimuli. Aim of this study was to assess the effects of H. pylori eradication in patients (pts) affected by PRP. METHODS: 46 pts (45 females and 1 male; mean age 37 ± 17 years) affected by PRP were evaluated. PRP was defined by the clinical manifestations of the attacks and by the amplitude of the digital plethysmographic signals measured in basal condition and after cold test. Discomfort feeling, duration and frequency of clinical attacks of PRP per week were assessed in the month preceding admission. H. pylori infection was diagnosed by 13C urea breath-test. The cytotoxins CagA and VacA were detected by Western Blot analysis in infected pts. Triple therapy consisting of amoxicillin (500 mg qid), clarithromycin (250 rid) and lansoprazole (30 mg bid) was given to H. pylori positive pts at the time of diagnosis for 7 days. Control of eradication was assessed after 6 weeks of finishing treatment. Clinical attacks of PRP per week were assessed after 6 and 12 weeks from finishing treatment. Non-infected pts affected by PRP were utilized as a control group. RESULTS: 78% (36 out of 46; mean age 38 ± 14 years) of pts affected by PRP remained infected by H. pylori. CagA and VacA were present in 86 and 76% of positive pts, respectively. No significant differences were found in discomfort feeling, duration and frequency of clinical attacks of PRP per week between infected and non-infected pts at the time of enrollment. 83% of infected pts were eradicated after therapy. 5 out of the 30 eradicated pts studied (17%) presented a complete disappearance of the clinical attacks of PRP during the follow up period. Discomfort feeling, duration and frequency of the attacks were significantly reduced in 72% of the remaining pts (18 out of 25 pts). Conversely, features of clinical attacks of PRP did not change significantly during the follow up in the control group of not infected PRP pts. CONCLUSIONS: this study confirm that H. pylori infection is extremely common in pts affected by PRP. CagA and VacA strains of the bacterium appear to be highly prelevant in infected pts. H. pylori eradication causes a marked reduction of the clinical symptoms of PRP. The multiplicity of substances produced, directly or indirectly, in response to H. pylori, such as cytokines and other cellular mediators of the acute phase response, could be involved in vessel dismotility of Raynaud phenomenon.

Published
1998

146. Chronic ethanol administration affects oxydative stress by ischemia/reperfusion in rat liver

Author

Giovanni Addolorato, Francesco Franceschi, Mara Simoncini, Mauro Bernardi, Aldo Roda, Paolo Pola, G. Gasbarrini, Enrico Roda, A. De Luca, G. Vagni, Patrizia Pasini, Bruno Nardo, and Alessandro Gasbarrini

Subjects
Ethanol administration, Hepatology, business.industry, Rat liver, Ischemia, medicine, Pharmacology, medicine.disease, business
Published
1998

148. Lumbar Chemical Sympathectomy in End Stage of Arterial Disease: Early and Late Results

Author

Roberto Flore, Carlo Vulpio, G. Salgarello, Geltrude Mingrone, Adriana Mascaro, C. Iannace, A. Borzone, Paolo Pola, Salvatore Agnes, Marco Castagneto, and M. De Santis

Subjects
Male, medicine.medical_specialty, Time Factors, Arteriosclerosis, medicine.drug_class, medicine.medical_treatment, Ischemia, Hemodynamics, Chemical, 030204 cardiovascular system & hematology, 03 medical and health sciences, 0302 clinical medicine, Diabetic Neuropathies, 80 and over, medicine, Humans, 030212 general & internal medicine, Sympathectomy, Stage (cooking), Aged, Aged, 80 and over, Bupivacaine, Chemotherapy, Foot, business.industry, Local anesthetic, Settore MED/09 - MEDICINA INTERNA, Sympathectomy, Chemical, Lumbosacral Region, Middle Aged, medicine.disease, Surgery, medicine.anatomical_structure, Anesthesia, Female, Cardiology and Cardiovascular Medicine, business, Blood Flow Velocity, Artery, medicine.drug
Abstract

Hemodynamic variables were used to evaluate the effectiveness of lumbar chemical sympathectomy in 20 patients with ischemic foot lesions. Early clinical improvement was obtained in 68% of the cases. The two-year cumulative limb salvage rate was 52%. Results indicate that lumbar chemical sympathectomy offers the same benefits as surgical sympathectomy and represents a useful al ternative in patients with advanced ischemic disease of the lower limb, decreas ing the rate and the level of amputations.

Published
1989

149. Peripheral Vascular Dynamics Studied by Calcium Ion Inhibition

Author

Savi L and Paolo Pola

Subjects
Adult, Time Factors, Nifedipine, Arteriosclerosis, Pyridines, chemistry.chemical_element, 030204 cardiovascular system & hematology, Diabetic angiopathy, Pharmacology, Calcium, 03 medical and health sciences, 0302 clinical medicine, Smooth muscle, medicine, Humans, Plethysmography, Impedance, 030212 general & internal medicine, Aged, business.industry, Antagonist, Muscle, Smooth, Anatomy, Middle Aged, medicine.disease, Peripheral, Vasomotor System, Vasomotor system, chemistry, Cardiology and Cardiovascular Medicine, business, Diabetic Angiopathies, medicine.drug
Abstract

The study of peripheral vasomotility through inhibition of parietal smooth muscle cells is of great clinical interest for both diagnostic and therapeutic reasons. It permits the differentiation of the functional clinical forms from the organic. And in organic forms, once any spastic component is eliminated, it determines the site and severity. On the basis of these premises we have developed a test for the study of vascular dynamics based on the use of nifedipine as antagonist of calcium ions.

Published
1978

150. The −174 G/C Polymorphism of the Interleukin-6 Gene Promoter is Associated with Peripheral Artery Occlusive Disease

Author

Michele Serricchio, Roberto Pola, Francesco Aloi, Andrea Flex, Enrico Pola, Angelo Santoliquido, Paolo Tondi, Eleonora Gaetani, Paolo Pola, A. Dal Lago, and Pierangelo Papaleo

Subjects
Male, medicine.medical_specialty, Pathology, Genotype, Arterial Occlusive Diseases, Gastroenterology, law.invention, Gene Frequency, law, Interleukin-6, Gene polymorphism, Peripheral artery occlusive disease, Internal medicine, medicine, Odds Ratio, Humans, Genetic Predisposition to Disease, Interleukin 6, Promoter Regions, Genetic, Gene, Polymerase chain reaction, Aged, Medicine(all), Aged, 80 and over, Peripheral Vascular Diseases, Polymorphism, Genetic, biology, business.industry, Interleukin-6, Promoter, Pathophysiology, Coronary arteries, medicine.anatomical_structure, Case-Control Studies, biology.protein, Surgery, Female, Gene polymorphism, Cardiology and Cardiovascular Medicine, business
Abstract

Objective and design: high plasma levels of Interleukin-6 (IL-6) are found in patients with atherosclerotic disorders. Recently, a common polymorphism of the IL-6 gene promoter, influencing the transcription rate of the gene, has been described and associated with atherosclerosis of carotid and coronary arteries. The objective of this study was to test whether IL-6 gene promoter polymorphism is associated with peripheral artery occlusive disease (PAOD) in a case-control study.Methods: IL-6 gene promoter polymorphism was evaluated by polymerase chain reaction followed by restriction enzyme analysis in 84 patients affected by PAOD and 183 controls.Results: the distribution of IL-6 genotypes was: patients with PAOD: 44 GG, 30 GC, 10 CC; control subjects: 53 GG, 80 GC, 50 CC. The GG genotype was significantly more common in the PAOD group (p

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