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119 results on '"POZZI, STEFANO"'

101. Natural killer cells fate at the draining lymph nodes: a physical portrait of the biological contest

Author

Sironi, L, Caccia, M, Gritti, N, Gorletta, T, Zanoni, I, Salvetti, C, Pozzi, S, Freddi, S, Daglio, S, Villa, C, Collini, M, D'Alfonso, L, Granucci, F, Chirico, G, SIRONI, LAURA, CACCIA, MICHELE, GORLETTA, TATIANA ALESSANDRA, ZANONI, IVAN, POZZI, STEFANO, FREDDI, STEFANO, DAGLIO, STEFANO CARLO, COLLINI, MADDALENA, D'ALFONSO, LAURA, GRANUCCI, FRANCESCA, CHIRICO, GIUSEPPE, Sironi, L, Caccia, M, Gritti, N, Gorletta, T, Zanoni, I, Salvetti, C, Pozzi, S, Freddi, S, Daglio, S, Villa, C, Collini, M, D'Alfonso, L, Granucci, F, Chirico, G, SIRONI, LAURA, CACCIA, MICHELE, GORLETTA, TATIANA ALESSANDRA, ZANONI, IVAN, POZZI, STEFANO, FREDDI, STEFANO, DAGLIO, STEFANO CARLO, COLLINI, MADDALENA, D'ALFONSO, LAURA, GRANUCCI, FRANCESCA, and CHIRICO, GIUSEPPE

Published
2011

102. Caratterizzazione del trascrittoma di PBMCs di pazienti affetti da aneurisma dell'aorta addominale e da ostruzione carotidea

Author

Pozzi, S, LAVITRANO, MARIALUISA, POZZI, STEFANO, Pozzi, S, LAVITRANO, MARIALUISA, and POZZI, STEFANO

Abstract

Atherosclerosis (also known as Arteriosclerotic Vascular Disease or ASVD) is the condition in which an artery wall thickens as the result of a build-up of fatty materials such as cholesterol. It is a syndrome affecting arterial blood vessels, a chronic inflammatory response in the walls of arteries, in large part due to the accumulation of macrophage white blood cells and promoted by Low-density lipoproteins (plasma proteins that carry cholesterol and triglycerides) without adequate removal of fats and cholesterol from the macrophages by functional high density lipoproteins (HDL). It is commonly referred to as a hardening or furring of the arteries. It is caused by the formation of multiple plaques within the arteries. Other arteriosclerotic disease is aortic aneurysm usually affecting the abdominal tract of the vessel. The prevalence of abdominal aortic aneurysm (AAA) varies ranging from 4.1% to 11.5% in European men. This disorder is characterized by localized structural deterioration of the aortic wall, leading to progressive dilatation and eventual aortic rupture. Rupture of AAA is responsible for 1.5% of the total mortality in males over 55 years of age. Both disease seem to share common causes in alteration in lipid metabolism and immune response against host and oxidised lipids, leading to a condition of chronic inflammation affecting all the vascular system, especially the big diameter arteries. There are several factors such as smoking, hypertension, hypercholesterolemia and male sex, which are well known risk factors for the development of AAA and carotid stenosis. However, better understanding of molecular mechanisms is an important step toward clarification of the pathophysiology, identification of genetic and molecular biomarkers and development of new therapeutic strategies for AAA and atherosclerosis in general. Gene expression profiling studies by microarray technologies are particularly appropriate to investigate and create working hypotheses to und

Published
2009

103. Mild-hypercholesterolemia exacerbates intimal hyperplasia after vascular injury by suppressing heme oxygenase-1 expression

Author

Busnelli, M, Froio, A, Bacci, M, Giunti, M, Forni, M, Cerrito, M, Giovannoni, R, Pozzi, S, Leone, B, Biasi, G, Lavitrano, M, BUSNELLI, MARCO, FROIO, ALBERTO, CERRITO, MARIA GRAZIA, GIOVANNONI, ROBERTO, POZZI, STEFANO, LEONE, BIAGIO EUGENIO, BIASI, GIORGIO MARIA, LAVITRANO, MARIALUISA, Bacci, ML, Busnelli, M, Froio, A, Bacci, M, Giunti, M, Forni, M, Cerrito, M, Giovannoni, R, Pozzi, S, Leone, B, Biasi, G, Lavitrano, M, BUSNELLI, MARCO, FROIO, ALBERTO, CERRITO, MARIA GRAZIA, GIOVANNONI, ROBERTO, POZZI, STEFANO, LEONE, BIAGIO EUGENIO, BIASI, GIORGIO MARIA, LAVITRANO, MARIALUISA, and Bacci, ML

Abstract

Intimal hyperplasia (IH) limits the success of many vascular interventions, including bypass grafting endarterectomy and stenting. IH following vascular injury is characterized by vascular smooth muscle cells proliferation and migration, matrix deposition, inflammation. The aim of the study was to investigate, in a mild-hypercholesterolemic pig model of vascular injury: i) the role of Heme Oxygenase-1 (HO-1) in the pathogenesis of IH; ii) the molecular mechanism of prevention and therapy mediated by atorvastatin; iii) the atorvastatin-mediated induction of HO-1 in response to vascular injury. Balloon injury (BI) was used to induce IH in pig carotid arteries. Pigs were divided in 3 groups (n=7 each): standard diet; high-cholesterol diet; high-cholesterol diet and atorvastatin (80 mg/die). Carotid sections were analyzed by morphometric and immunohistochemical analyses. Hemochrome, cholesterolemia, proinflammatory cytokines profiles were also evaluated. Hypercholesterolemia induced a significant increase of total and LDL-cholesterol, exacerbated IH, increased extracellular matrix deposition, inhibited HO-1 expression and increased the local and systemic inflammatory state compared to standard diet. Atorvastatin prevented IH development by enhancing HO-1 expression, reducing the number of T-cell infiltrating the site of vascular injury, and lowering the plasmatic concentration of proinflammatory cytokines. In conclusion: i) a high-cholesterol diet induces a persistent state of vascular inflammation that worsen the vascular response following BI; ii) atorvastatin has a protective role in the pathogenesis and outcome of inflammatory response following vascular injury; iii) atorvastatin prevents IH inducing HO-1 expression in the vascular wall.

Published
2009

105. Heme oxygenase-1 and nitric oxide in the vasculature: in vivo balloon injury and in vitro VSMC studies in rats

Author

Scagliarini, A, Cerrito, M, Froio, A, Mainetti, L, Liloia, A, Turolo, S, Villa, M, Bellucci, S, Pozzi, S, Giovannoni, R, Leone, B, Bach, F, Lavitrano, M, SCAGLIARINI, ALESSANDRA, CERRITO, MARIA GRAZIA, FROIO, ALBERTO, POZZI, STEFANO, GIOVANNONI, ROBERTO, LEONE, BIAGIO EUGENIO, LAVITRANO, MARIALUISA, Bach, FH, Scagliarini, A, Cerrito, M, Froio, A, Mainetti, L, Liloia, A, Turolo, S, Villa, M, Bellucci, S, Pozzi, S, Giovannoni, R, Leone, B, Bach, F, Lavitrano, M, SCAGLIARINI, ALESSANDRA, CERRITO, MARIA GRAZIA, FROIO, ALBERTO, POZZI, STEFANO, GIOVANNONI, ROBERTO, LEONE, BIAGIO EUGENIO, LAVITRANO, MARIALUISA, and Bach, FH

Published
2007

107. Evaluation der Ökomassnahmen: Bereich Biodiversität

Author

Herzog, Felix, Walter, Thomas, Aviron, Stéphanie, Bigler, Franz, Birrer, Simon, Bosshart, Stephan, Buholzer, Serge, Derron, Jacques, Dreier, Suzanne, Duelli, Peter, Eggenschwiler, Lisa, Heynen, Daniela, Hochstetter, Sebastian, Hofer, Gabriela, Holzgang, Otto, Jacot, Katja, Jeanneret, Philippe, Kampmann, Dorothea, Kéry, Marc, Klaus, Iris, Kleijn, David, Knop, Eva, Kohli, Lukas, Kühne, Andrea, Luka, Henryk, Oberholzer, Barbara, Obrist, Martin K., Pfiffner, Lukas, Pearson, Sarah, Pozzi, Stefano, Roux, Olivier, Schneider, Krin, Schüpbach, Beatrice, Spiess, Martin, Wermeille, Emmanuel, Wolff, Matthias, Herzog, Felix, Walter, Thomas, Aviron, Stéphanie, Bigler, Franz, Birrer, Simon, Bosshart, Stephan, Buholzer, Serge, Derron, Jacques, Dreier, Suzanne, Duelli, Peter, Eggenschwiler, Lisa, Heynen, Daniela, Hochstetter, Sebastian, Hofer, Gabriela, Holzgang, Otto, Jacot, Katja, Jeanneret, Philippe, Kampmann, Dorothea, Kéry, Marc, Klaus, Iris, Kleijn, David, Knop, Eva, Kohli, Lukas, Kühne, Andrea, Luka, Henryk, Oberholzer, Barbara, Obrist, Martin K., Pfiffner, Lukas, Pearson, Sarah, Pozzi, Stefano, Roux, Olivier, Schneider, Krin, Schüpbach, Beatrice, Spiess, Martin, Wermeille, Emmanuel, and Wolff, Matthias

Abstract

1993 führte der Bund ökologische Direktzahlungen ein; seit 1999 ist die Erbringung des ökologischen Leistungsnachweises (ÖLN) durch die Landwirtschaftsbetriebe die Voraussetzung zum Bezug von Direktzahlungen. Heute werden 97 % der landwirtschaftlichen Nutzfläche nach den Regeln des ÖLN bewirtschaftet. Die wichtigste Massnahme des ÖLN, welche einen Einfluss auf die Biodiversität hat, ist, dass die Betriebe 7 % ihrer landwirtschaftlichen Nutzfläche (LN) als ökologische Ausgleichsflächen (öAF) auszuweisen haben (bei Spezialkulturen 3,5 %). Weitere Anforderungen des ÖLN (ausgeglichene Nährstoffbilanz, geregelte Fruchtfolge, Bodenschutz, gezielter Einsatz von Pflanzenschutzmitteln, tiergerechte Haltung der Nutztiere) können ebenfalls einen Einfluss haben, stehen jedoch weniger im Vordergrund.

Published
2005

113. Number one

Author

Pozzi, Stefano

Subjects
Educational software -- Evaluation, Education, NCET Number Grids Pack (Mathematical software)
Published
1990

114. Alla Santittá di Nostro Signore Papa Benedetto XIV la nuova topografia di Roma

Author

Campana, Pietro , 1725 or 1727-approximately 1765, Nolli, Carlo , -approximately 1770, Pozzi, Stefano , 1699-1768, Nolli, Giambattista , approximately 1692-1756, Campana, Pietro , 1725 or 1727-approximately 1765, Nolli, Carlo , -approximately 1770, Pozzi, Stefano , 1699-1768, and Nolli, Giambattista , approximately 1692-1756

Abstract

ossequiosamente offerisce e dedica l'umilissimo servo Giambattista Nolli Comasco; si stampa in Roma con Privil. del Som.o Pontefice e licenza de Superioriori; Rocco Pazzi Romano Pietro Campana da Soriano e Carlo Nolli inc.; Stefano Pozzi Pit. inv. e delin., Relief shown by hachures., Shows names of streets, buildings, plazas, churches, drainage, and other points of interest., Lower portion of map with engravings of classical figures, motifs, and architectural images and papal insignia and motifs., Historiated title cartouche with architectural motif., At lower left and right borders of index: Car. Nolli inc., Available also as a digital image through the Harvard University Web site.

115. Hesperi et Phosphori nova phaenomena sive Observationes circa planetam Veneris...

Author

Bianchini, Francesco, 1662-1729, Salvioni, Giovanni Maria, 1676-1755, Briga, Melchior dalla, 1686-1749, Pozzi, Stefano, 1699-1768, Pozzi, Rocco, m. ca. 1780, Bianchini, Francesco, 1662-1729, Salvioni, Giovanni Maria, 1676-1755, Briga, Melchior dalla, 1686-1749, Pozzi, Stefano, 1699-1768, and Pozzi, Rocco, m. ca. 1780

Abstract

Reproducción digital. Madrid : Ministerio de Educación, Cultura y Deporte. Subdirección General de Coordinación Bibliotecaria, 2017, Datos de ed. preceden al autor, Sign.: a4, A-L4, M2, Port. a dos tintas, Port. con grab. calc., Grab. calc. en h. anterior a port.: "Sthepanus Pozzi Inu. et del. Roccus Pozzi incid.", Ilustraciones calc. intercaladas en el texto, 12 h. de grab. calc. al final del texto

117. ASPECT-BET: An sdd-SPECTrometer for BETa decay studies

Author

Matteo Biassoni, Chiara Brofferio, Silvia Capelli, Francesco Cappuzzello, Marco Carminati, Manuela Cavallaro, Luigi Coraggio, Oliviero Cremonesi, Giovanni De Gregorio, Carlo Fiorini, Nunzio Itaco, Andrea Nava, Stefano Pozzi, Biassoni, Matteo, Brofferio, Chiara, Capelli, Silvia, Cappuzzello, Francesco, Carminati, Marco, Cavallaro, Manuela, Coraggio, Luigi, Cremonesi, Oliviero, Gregorio, Giovanni De, Fiorini, Carlo, Itaco, Nunzio, Nava, Andrea, Pozzi, Stefano, Gargano, A, De Gregorio, G, Coraggio, L, Itaco, N, Biassoni, M, Brofferio, C, Capelli, S, Cappuzzello, F, Carminati, M, Cavallaro, M, Cremonesi, O, Gregorio, G, Fiorini, C, Nava, A, and Pozzi, S

Subjects
History, beta decay, beta spectrum shape, nuclear matrix elements, Silicon Drift Detectors, Computer Science Applications, Education
Abstract

We present the status of the ASPECT-BET (An sdd-SPECTrometer for BETa decay studies) project which is aimed at developing a new detection strategy to perform high-precision, high-accuracy measurements of the energy spectra of beta decays of interest for the physics community, in particular in the field of nuclear physics, double beta decay and reactor neutrinos. The aim is to exploit a relatively novel spectroscopic technique based on Silicon Drift Detectors. An SDD-spectrometer, equipped with all the ancillary detectors required to reject events with only a partial energy deposition in the main sensitive elements, will provide high-statistics and virtually zero-background data. In order to isolate and study the systematic uncertainties, the statistical error on the measured spectra has to be reduced to a negligible level, balancing source activity, measurement duration and background. Reliable and well understood Montecarlo simulations are a key component of this application, as they provide a model for the response functions of the spectrometer, to be deconvolved from the data in order to correctly reconstruct the original spectral shapes. Thanks to the flexibility of the SDD detector technology, the here presented spectrometer could be coupled to a variety of beta sources, ranging from nuclei deposited on the surface of SDDs to minimise source self-absorpion to short-lived isotopes created and collected at unstable isotope beams like ISOLDE at CERN or the exotic beams at LNS, Catania. The current status of the technology, as well as some preliminary sensitivity studies, are presented and discussed.

Published
2023

118. Status of the CUORE and results from the CUORE-0 neutrinoless double beta decay experiments

Author

M. M. Deninno, S. Di Domizio, C. Zarra, Lucia Canonica, B. K. Fujikawa, Stefano Pozzi, Stefano Dell'Oro, F. Bellini, X. Liu, Massimiliano Nastasi, L. Gironi, F. T. Avignone, A. Giuliani, T. I. Banks, N. Casali, S. Pirro, M. Vignati, A. Bersani, F. Orio, Massimiliano Clemenza, Carlo Cosmelli, C. Rosenfeld, M. Balata, G. Bari, Vladimir Datskov, L. Pattavina, G. Ventura, S. Trentalange, S. Copello, N. Moggi, C. Nones, Yu-Gang Ma, B. S. Wang, R. J. Creswick, P. Gorla, Samuele Sangiorgio, Stefano Nisi, O. Azzolini, Y. L. Li, Oliviero Cremonesi, Marisa Pedretti, A. Nucciotti, C. Brofferio, H. Z. Huang, F. Ferroni, C. Tomei, M. Tenconi, Emanuele Ferri, Ettore Fiorini, H. A. Farach, Andrea Giachero, M. Faverzani, Eugene E. Haller, G. Fernandes, L. Taffarello, Marco Pallavicini, Jeremy S. Cushman, W. D. Tian, Alan R. Smith, N. Chott, G. Pessina, M. L. Di Vacri, Davide Chiesa, K. E. Lim, Nicholas Scielzo, A. Camacho, S. Zucchelli, L. Carbone, C. Bucci, T. D. Gutierrez, Guimin Zhang, Jeffrey W. Beeman, John Wilson, A. Dally, Claudio Gotti, M. Maino, C. Pira, Yu. G. Kolomensky, Luigi Cappelli, Simone Capelli, H. W. Wang, R. W. Kadel, G. Keppel, D. R. Artusa, Larissa M. Ejzak, B. X. Zhu, T. O'Donnell, Monica Sisti, Lorenzo Cassina, V. Pettinacci, L. Cardani, C. Maiano, Lindley Winslow, X. Z. Cai, L. Wielgus, Carlo Ligi, C. Rusconi, G. Piperno, S. Morganti, M. I. Martínez, Ioan Dafinei, L. Zanotti, M. Pavan, A. Drobizhev, D. Orlandi, Kevin Hickerson, M. A. Franceschi, D. Q. Fang, C. Pagliarone, T. Wise, V. Palmieri, A. Caminata, Elena Sala, Ezio Previtali, Y. Mei, Eric B. Norman, T. Napolitano, R. Hennings-Yeomans, Xi-Guang Cao, K. M. Heeger, M. Biassoni, Ke Han, Reina H. Maruyama, Stuart J. Freedman, J. L. Ouellet, A. Woodcraft, F. Terranova, Sisti, M, Artusa, D, Avignone, F, Azzolini, O, Balata, M, Banks, T, Bari, G, Beeman, J, Bellini, F, Bersani, A, Biassoni, M, Brofferio, C, Bucci, C, Cai, X, Camacho, A, Caminata, A, Canonica, L, Cao, X, Capelli, S, Cappelli, L, Carbone, L, Cardani, L, Casali, N, Cassina, L, Chiesa, D, Chott, N, Clemenza, M, Copello, S, Cosmelli, C, Cremonesi, O, Creswick, R, Cushman, J, Dafinei, I, Dally, A, Datskov, V, Dell'Oro, S, Deninno, M, Di Domizio, S, di Vacri, M, Drobizhev, A, Ejzak, L, Fang, D, Farach, H, Faverzani, M, Fernandes, G, Ferri, E, Ferroni, F, Fiorini, E, Franceschi, M, Freedman, S, Fujikawa, B, Giachero, A, Gironi, L, Giuliani, A, Gorla, P, Gotti, C, Gutierrez, T, Haller, E, Han, K, Heeger, K, Hennings Yeomans, R, Hickerson, K, Huang, H, Kadel, R, Keppel, G, Kolomensky, Y, Li, Y, Ligi, C, Lim, K, Liu, X, Ma, Y, Maiano, C, Maino, M, Martinez, M, Maruyama, R, Mei, Y, Moggi, N, Morganti, S, Napolitano, T, Nastasi, M, Nisi, S, Nones, C, Norman, E, Nucciotti, A, O'Donnell, T, Orio, F, Orlandi, D, Ouellet, J, Pagliarone, C, Pallavicini, M, Palmieri, V, Pattavina, L, Pavan, M, Pedretti, M, Pessina, G, Pettinacci, V, Piperno, G, Pira, C, Pirro, S, Pozzi, S, Previtali, E, Rosenfeld, C, Rusconi, C, Sala, E, Sangiorgio, S, Scielzo, N, Smith, A, Taffarello, L, Tenconi, M, Terranova, F, Tian, W, Tomei, C, Trentalange, S, Ventura, G, Vignati, M, Wang, B, Wang, H, Wielgus, L, Wilson, J, Winslow, L, Wise, T, Woodcraft, A, Zanotti, L, Zarra, C, Zhang, G, Zhu, B, Zucchelli, S, Sisti, M., Artusa, D.R., Avignone, F.T., Azzolini, O., Balata, M., Banks, T.I., Bari, G., Beeman, J., Bellini, F., Bersani, A., Biassoni, M., Brofferio, C., Bucci, C., Cai, X.Z., Camacho, A., Caminata, A., Canonica, L., Cao, X.G., Capelli, S., Cappelli, L., Carbone, L., Cardani, L., Casali, N., Cassina, L., Chiesa, D., Chott, N., Clemenza, M., Copello, S., Cosmelli, C., Cremonesi, O., Creswick, R.J., Cushman, J.S., Dafinei, I., Dally, A., Datskov, V., Dell'Oro, S., Deninno, M.M., Di Domizio, S., di Vacri, M.L., Drobizhev, A., Ejzak, L., Fang, D.Q., Farach, H.A., Faverzani, M., Fernandes, G., Ferri, E., Ferroni, F., Fiorini, E., Franceschi, M.A., Freedman, S.J., Fujikawa, B.K., Giachero, A., Gironi, L., Giuliani, A., Gorla, P., Gotti, C., Gutierrez, T.D., Haller, E.E., Han, K., Heeger, K.M., Hennings-Yeomans, R., Hickerson, K.P., Huang, H.Z., Kadel, R., Keppel, G., Kolomensky, Yu.G., Li, Y.L., Ligi, C., Lim, K.E., Liu, X., Ma, Y.G., Maiano, C., Maino, M., Martinez, M., Maruyama, R.H., Mei, Y., Moggi, N., Morganti, S., Napolitano, T., Nastasi, M., Nisi, S., Nones, C., Norman, E.B., Nucciotti, A., O'Donnell, T., Orio, F., Orlandi, D., Ouellet, J.L., Pagliarone, C.E., Pallavicini, M., Palmieri, V., Pattavina, L., Pavan, M., Pedretti, M., Pessina, G., Pettinacci, V., Piperno, G., Pira, C., Pirro, S., Pozzi, Stefano, Previtali, E., Rosenfeld, C., Rusconi, C., Sala, E., Sangiorgio, S., Scielzo, N.D., Smith, A.R., Taffarello, L., Tenconi, M., Terranova, F., Tian, W.D., Tomei, C., Trentalange, S., Ventura, G., Vignati, M., Wang, B.S., Wang, H.W., Wielgus, L., Wilson, J., Winslow, L.A., Wise, T., Woodcraft, A., Zanotti, L., Zarra, C., Zhang, G.Q., Zhu, B.X., and Zucchelli, S.

Subjects
Physics, Particle physics, Nuclear and High Energy Physics, 010308 nuclear & particles physics, Bolometer, Bolometers, 01 natural sciences, Beta decay, Double beta decay, Particle detector, Massless particle, Nuclear physics, CUORE, Neutrino mass, 0103 physical sciences, Neutrino, 010306 general physics, Neutrino ma, Radioactive decay, Lepton
Abstract

CUORE is a 741kg array of TeO 2 bolometers for the search of neutrinoless double beta decay of 130 Te. The detectoris being constructed at the Laboratori Nazionali del Gran Sasso, Italy, where it will start taking data in 2015. If thetarget background of 0.01counts/(keVkgy) will be reached, in five years of data taking CUORE will have a 1˙halflife sensitivity of 10 26 y. CUORE-0 is a smaller experiment constructed to test and demonstrate the performancesexpected for CUORE. The detector is a single tower of 52 CUORE-like bolometers that started taking data in spring2013. The status and perspectives of CUORE will be discussed, and the first CUORE-0 data will be presented.Keywords: Double beta decay, Neutrino mass, Bolometers1. IntroductionNeutrinos are massive particles. A beautiful proof ofthis important property was obtained by neutrino oscil-lation experiments more than a decade ago. Since then,the key role of neutrinoless double beta decay searcheshas been established, as attested by the growing numberof experimental proposals in the last years.Neutrinoless double beta decay ( 0 ) is a proposedvery rare nuclear process in which a nucleus transformsinto its (A,Z+2) isobar with the emission of two elec-trons. While the two neutrino channel ( 2 ) – wheretwo neutrinos are contemporary emitted in the decay – isallowed by the Standard Model of Particle Physics andhas been observed experimentally in a dozen of isotopeswith half-lives of the order 10

Published
2016

119. The commissioning of the CUORE experiment: The mini-tower run

Author

K. Wilson, C. Pagliarone, R. Hennings-Yeomans, R. J. Creswick, T. Wise, Jonathan Ouellet, G. Bari, L. Taffarello, Maria Laura Di Vacri, B. Schmidt, A. Caminata, Sergio Di Domizio, L. Pattavina, A. D'Addabbo, S. J. Freedman, Claudio Gotti, A. Bersani, Y. Mei, Deqing Fang, Luigi Cappelli, C. Pira, Xi-Guang Cao, K. M. Heeger, G. Keppel, Guoqiang Zhang, A. Leder, Oliviero Cremonesi, N. Moggi, Carlo Ligi, S. S. Nagorny, L. Gironi, F. T. Avignone, M. M. Deninno, Stefano Dell'Oro, Vivek Singh, Lorenzo Cassina, Massimiliano Clemenza, Carlo Cosmelli, Ke Han, A. Branca, Reina H. Maruyama, Samuele Sangiorgio, Lucia Canonica, A. Nucciotti, C. Alduino, Nicholas Scielzo, T. D. Gutierrez, F. Bellini, D. Santone, N. Casali, F. Terranova, Ioan Dafinei, A. Drobizhev, M. Faverzani, Y. u. G. Kolomensky, C. Bucci, H. Z. Huang, A. Giuliani, F. Reindl, Davide Chiesa, M. Pavan, K. E. Lim, Stefano Zucchelli, M. A. Franceschi, C. Rosenfeld, C. Brofferio, M. I. Martínez, Lindley Winslow, J. Schmidt, Claudia Nones, S. Zimmermann, Ettore Fiorini, J. S. Wilson, P. Gorla, F. Ferroni, Andrea Giachero, Laura Cardani, Emanuele Ferri, B. K. Fujikawa, Stefano Pozzi, Hongwei Wang, L. Zanotti, Monica Sisti, C. J. Davis, M. Vignati, A. Camacho, N. Chott, K. Alfonso, Ezio Previtali, B. Welliver, Silvia Capelli, Massimiliano Nastasi, Laura Gladstone, S. Copello, Paolo Carniti, C. Rusconi, S. L. Wagaarachchi, V. Novati, Stefano Pirro, D. D'Aguanno, L. Marini, T. O'Donnell, Irene Nutini, Yu-Gang Ma, Claudia Tomei, Michi Sakai, B. S. Wang, Marco Pallavicini, O. Azzolini, G. Pessina, Jeremy S. Cushman, Giovanni Benato, V. Palmieri, Eric B. Norman, Silvio Morganti, T. Napolitano, M. Biassoni, Centre de Sciences Nucléaires et de Sciences de la Matière (CSNSM), Université Paris-Sud - Paris 11 (UP11)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Département de Physique des Particules (ex SPP) (DPP), Institut de Recherches sur les lois Fondamentales de l'Univers (IRFU), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay, CUORE, Copello, S, Alduino, C, Alfonso, K, Avignone, F, Azzolini, O, Bari, G, Bellini, F, Benato, G, Bersani, A, Biassoni, M, Branca, A, Brofferio, C, Bucci, C, Camacho, A, Caminata, A, Canonica, L, Cao, X, Capelli, S, Cappelli, L, Cardani, L, Carniti, P, Casali, N, Cassina, L, Chiesa, D, Chott, N, Clemenza, M, Cosmelli, C, Cremonesi, O, Creswick, R, Cushman, J, D'Addabbo, A, D'Aguanno, D, Dafinei, I, Davis, C, Dell'Oro, S, Deninno, M, Di Domizio, S, Di Vacri, M, Drobizhev, A, Fang, D, Faverzani, M, Ferri, E, Ferroni, F, Fiorini, E, Franceschi, M, Freedman, S, Fujikawa, B, Giachero, A, Gironi, L, Giuliani, A, Gladstone, L, Gorla, P, Gotti, C, Gutierrez, T, Han, K, Heeger, K, Hennings-Yeomans, R, Huang, H, Keppel, G, Kolomensky, Y, Leder, A, Ligi, C, Lim, K, Ma, Y, Marini, L, Martinez, M, Maruyama, R, Mei, Y, Moggi, N, Morganti, S, Nagorny, S, Napolitano, T, Nastasi, M, Nones, C, Norman, E, Novati, V, Nucciotti, A, Nutini, I, O'Donnell, T, Ouellet, J, Pagliarone, C, Pallavicini, M, Palmieri, V, Pattavina, L, Pavan, M, Pessina, G, Pira, C, Pirro, S, Pozzi, S, Previtali, E, Reindl, F, Rosenfeld, C, Rusconi, C, Sakai, M, Sangiorgio, S, Santone, D, Schmidt, B, Schmidt, J, Scielzo, N, Singh, V, Sisti, M, Taffarello, L, Terranova, F, Tomei, C, Vignati, M, Wagaarachchi, S, Wang, B, Wang, H, Welliver, B, Wilson, J, Wilson, K, Winslow, L, Wise, T, Zanotti, L, Zhang, G, Zimmermann, S, Zucchelli, S, Département de Physique des Particules (ex SPP) (DPhP), Copello, Simone, Alduino, Christopher, Alfonso, Krystal, Avignone III, Frank T., Azzolini, Oscar, Bari, Giacomo, Bellini, Fabio, Benato, Giovanni, Bersani, Andrea, Biassoni, Matteo, Branca, Antonio, Brofferio, Chiara, Bucci, Carlo, Camacho, Andrea, Caminata, Alessio, Canonica, Lucia, Cao, Xi-Guang, Capelli, Silvia, Cappelli, Luigi, Cardani, Laura, Carniti, Paolo, Casali, Nicola, Cassina, Lorenzo, Chiesa, Davide, Chott, Nichola, Clemenza, Massimiliano, Cosmelli, Carlo, Cremonesi, Oliviero, Creswick, Rick J., Cushman, Jeremy S., D'Addabbo, Antonio, Dafinei, Ioan, D'Aguanno, Damiano, Davis, Christopher J., Dell'Oro, Stefano, Deninno, Maria Maddalena, Di Domizio, Sergio, Di Vacri, Maria Laura, Drobizhev, Alexey, Fang, Deqing, Faverzani, Marco, Ferri, Elena, Ferroni, Fernando, Fiorini, Ettore, Franceschi, Massimo Alberto, Freedman, Stuart J., Fujikawa, Brian K., Giachero, Andrea, Gironi, Luca, Giuliani, Andrea, Gladstone, Laura, Gorla, Paolo, Gotti, Claudio, Gutierrez, Thomas D., Han, Ke, Heeger, Karsten M., Hennings-Yeomans, Raul, Huang, Huan Zhong, Keppel, Giorgio, Kolomensky, Yury G., Leder, Alex, Ligi, Carlo, Lim, Kyungeun, Ma, Yu-Gang, Marini, Laura, Martinez, Maria, Maruyama, Reina H., Mei, Yuan, Moggi, Niccolò, Morganti, Silvio, Nagorny, Sergey, Napolitano, Tommaso, Nastasi, Massimiliano, Nones, Claudia, Norman, Eric, Novati, Valentina, Nucciotti, Angelo, Nutini, Irene, O'Donnell, Tommy, Ouellet, Jonathan, Pagliarone, Carmine, Pallavicini, Marco, Palmieri, Vincenzo, Pattavina, Luca, Pavan, Maura, Pessina, Gianluigi, Pira, Cristian, Pirro, Stefano, Pozzi, Stefano, Previtali, Ezio, Reindl, Florian, Rosenfeld, Carl, Rusconi, Claudia, Sakai, Michi, Sangiorgio, Samuele, Santone, Daria, Schmidt, Ben, Schmidt, Jedediah, Scielzo, Nicholas D., Singh, Vivek, Sisti, Monica, Taffarello, Luca, Terranova, Francesco, Tomei, Claudia, Vignati, Marco, Wagaarachchi, Sachi, Wang, Barbara S., Wang, Hongwei, Welliver, Brad, Wilson, Jeffrey, Wilson, Kevin, Winslow, Lindley, Wise, Tom, Zanotti, Luigi, Zhang, Guoqiang, Zimmermann, Sergio, and Zucchelli, Stefano

Subjects
Cryostat, noise, data acquisition, Nuclear engineering, energy resolution, Cryogenics, fabrication, 7. Clean energy, Noise (electronics), tellurium: oxygen, law.invention, crystal, CUORE, Data acquisition, bolometer, law, Double beta decay, [PHYS.PHYS.PHYS-INS-DET]Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det], activity report, Physics, Activity report | electronics: readout | cryogenics | crystal | bolometer | CUORE | energy resolution | data acquisition | background | noise | tellurium: oxygen | performance | fabrication, Nuclear physics, Neutrini, background, Bolometer, Neutrinoless Double Beta Decay, Cryogenic Detector, Bolometer, cryogenics, electronics: readout, Tower, performance
Abstract

© Copyright owned by the author(s). CUORE is a ton-scale experiment approaching the data taking phase in Gran Sasso National Laboratory. Its primary goal is to search for the neutrinoless double-beta decay in 130 Te using 988 crystals of tellurim dioxide. The crystals are operated as bolometers at about 10 mK taking advantage of one of the largest dilution cryostat ever built. Concluded in March 2016, the cryostat commissioning consisted in a sequence of cool down runs each one integrating new parts of the apparatus. The last run was performed with the fully configured cryostat and the thermal load at 4 K reached the impressive mass of about 14 tons. During that run the base temperature of 6.3 mK was reached and maintained for more than 70 days. An array of 8 crystals, called mini-tower, was used to check bolometers operation, readout electronics and DAQ. Results will be presented in terms of cooling power, electronic noise, energy resolution and preliminary background measurements.

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