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110. Limpet teeth microstructure unites auxeticity with extreme strength and high stiffness

Author

Oh, Sang Ho, primary, Kim, Jin-Kyung, additional, Liu, Yue, additional, Wurmshuber, Michael, additional, Peng, Xiang-Long, additional, Seo, Jinsol, additional, Jeong, Jiwon, additional, Wang, Zhen, additional, Wilmers, Jana, additional, Soyarslan, Celal, additional, Kim, Jongil, additional, Kittiwirayanon, Boonsita, additional, Jeong, Jeehun, additional, Kim, Hyo-Jeong, additional, Huh, Yang Hoon, additional, Kiener, Daniel, additional, Bargmann, Swantje, additional, and Gao, Huajian, additional

Published
2022
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112. Wearable Surface‐Lighting Micro‐Light‐Emitting Diode Patch for Melanogenesis Inhibition

Author

Lee, Jae Hee, primary, Ahn, Yuri, additional, Lee, Han Eol, additional, Jang, You Na, additional, Park, A. Yeon, additional, Kim, Shinho, additional, Jung, Young Hoon, additional, Sung, Sang Hyun, additional, Shin, Jung Ho, additional, Lee, Seung Hyung, additional, Park, Sang Hyun, additional, Kim, Ki Soo, additional, Jang, Min Seok, additional, Kim, Beom Joon, additional, Oh, Sang Ho, additional, and Lee, Keon Jae, additional

Published
2022
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119. Interface‐Controlled Biomimetic Intrafibrillar Mineralization of Collagen: Effect of Ca2+/[PO4]3− Concentration Ratio.

Author

Amornkitbamrung, Urasawadee, In, Yongjae, Lee, Jung Heon, Wang, Zhen, Oh, Sang Ho, Shin, Heungsoo, Yoon, Dae Sung, and Shin, Hyunjung

Subjects
MINERALIZATION, COLLAGEN, PHASE transitions, CALCIUM phosphate, BODY fluids, CRYSTALLIZATION kinetics, HYDROXYAPATITE
Abstract

Mineralized fibrils are important building blocks in bone tissue, formed by the hierarchical assembly of collagen molecules and crystalline hydroxyapatite (HAp). The mineralization pathway of HAp is reported as a nonclassical‐crystallization, but the nanoconfined crystallization in collagen fibrils remains poorly understood. The mechanism of intrafibrillar mineralization of collagen‐PDA fibrils in modified‐simulated body fluid (m‐SBF) solution is studied. Collagen‐amorphous calcium phosphate (ACP) fibrils are obtained by assembling collagen‐PDA fibrils with polyaspartic acid (pAsp) as a stabilizer. The ACP undergoes a phase transformation to HAp within the fibrils upon adjusting the phosphate concentration. It is found that the phase transformation of ACP to HAp in collagen fibrils can be accelerated with a 12 h incubation with 1/10 ratio of Ca2+ to [PO4]3−. A lower ratio of 1/1 and 1/5 results in a much slower phase transformation. This finding suggests that an elevated concentration of [PO4]3− is crucial for faster phase transformation. The relationship between the crystallization rate of HAp in the fibrils and the degree of mineralization is found to be linear in all cases, indicating an interface‐controlled process. This gives a better understanding of the mechanism of HAp mineralization in collagen fibrils, providing an effective approach to material design. [ABSTRACT FROM AUTHOR]

Published
2023
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126. Oblique Axis Hypothenar Free Flaps: Tips for Harvesting Larger Flaps with Minimal Donor Site Morbidity.

Author

Oh, Sang Ho and Chung, Jae In

Subjects
*FREE flaps, *HARVESTING, *KELOIDS, *ELECTRONIC health records, *ULNAR nerve, *HARVESTING time
Abstract

Background Hypothenar free flaps (HTFFs) have been widely used for reconstructing palmar defects. Although previous anatomical and clinical studies of HTFF have been conducted, this technique still has some limitations. In this study, we describe some tips for large flap design that allows for easy harvesting of HTFFs with minimal donor site morbidity. Methods A total of 14 HTFF for hand defect reconstruction were recorded. The oblique flap was designed in the proximal HT area following relaxed skin tension line along the axis between fourth web space and 10 mm ulnar side of pisiform. A flap pedicle includes one or two perforators with ulnar digital artery and HT branch of basilic vein. In addition, innervated HTFF can be harvested with a branch of ulnar digital nerve. Electronic medical records were reviewed to obtain data on patients' information, operative details, and follow-up period. In addition, surgical outcome score was obtained from the patient, up to 10 points, at the last follow-up. Results Mean harvest time was 46 minutes, and two perforators were included in 10 cases. The mean flap area was 10.84 cm 2. There were no problems such as donor site depression, scar contracture, keloids, wound dehiscence, numbness or neuroma pain at donor sites, and hypersensitivity or cold intolerance at flap site, either functionally or aesthetically. Conclusion Palmar defect reconstruction is challenging for hand surgeons. However, large HTFF can be harvested without complications using the oblique axis HTFF technique. We believe our surgical tips increase utility of HTFF for palmar defect reconstruction. [ABSTRACT FROM AUTHOR]

Published
2023
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