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502 results on '"Noma, Kazuhiro"'

106. Flap Reconstruction for Esophageal Perforation Following Anterior Cervical Plate Fixation

Author

Morita, Mio, Matsumoto, Hiroshi, Shirakawa, Yasuhiro, Noma, Kazuhiro, Tanabe, Shunsuke, and Kimata, Yoshihiro

Subjects
Adult, Male, reconstruction, Esophageal Perforation, jejunal free flap, Middle Aged, pectoralis major flap, Surgical Flaps, Fracture Fixation, Internal, Cervical Vertebrae, anterior cervical plate fixation, Humans, Female, Bone Plates
Abstract

Anterior cervical plate fixation is a common surgical treatment for cervical spine trauma, disc herniation, or cervical spondylosis. Esophageal perforation following anterior cervical plate fixation is a rare but serious complication. Management of esophageal perforation is controversial; however, we suggest treating most cases surgically because this condition is slow to heal and often fatal. We managed 2 cases of esophageal perforation following anterior cervical plate fixation by flap reconstruction with the pectoralis major muscle in one case and a jejunal free flap in the other. Here, we report our experience and review the surgical indications.

Published
2019

107. Localization of heparanase in esophageal cancer cells: respective roles in prognosis and differentiation

Author

Ohkawa, Takaomi, Naomoto, Yoshio, Takaoka, Munenori, Nobuhisa, Tetsuji, Noma, Kazuhiro, Motoki, Takayuki, Murata, Toshihiro, Uetsuka, Hirokazu, Kobayashi, Masahiko, Shirakawa, Yasuhiro, Yamatsuji, Tomoki, Matsubara, Nagahide, Matsuoka, Junji, Haisa, Minoru, Gunduz, Mehmet, Tsujigiwa, Hidetsugu, Nagatsuka, Hitoshi, Hosokawa, Masao, Nakajima, Motowo, and Tanaka, Noriaki

Published
2004
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108. Intracorporeal semi‐hand‐sewn Billroth I reconstruction in total laparoscopic distal gastrectomy.

Author

Kikuchi, Satoru, Kuroda, Shinji, Nishizaki, Masahiko, Kuwada, Kazuya, Takata, Nobuo, Kakiuchi, Yoshihiko, Yano, Shuya, Noma, Kazuhiro, Kagawa, Shunsuke, and Fujiwara, Toshiyoshi

Subjects
SUTURING, SURGICAL complications, LAPAROSCOPIC surgery, GASTRECTOMY, OPERATIVE surgery, LYMPHADENECTOMY
Abstract

Introduction: Intracorporeal Billroth I (B‐I) reconstruction using an endoscopic linear stapler (ELS) is widely performed in total laparoscopic distal gastrectomy. However, conventional procedures require many ELSs for anastomosis. Here, we introduce the novel intracorporeal semi‐hand‐sewn (SHS) B‐I reconstruction. Materials and surgical technique: After the transection of stomach and duodenum using ELS following adequate lymph node dissection, small entry holes were made on the anterior wall in the greater curvature of the stomach and the duodenal stump. The posterior walls of both the remnant stomach and the duodenum were attached with the ELS and fired to create the posterior wall of the B‐I anastomosis. All the transection line of the duodenum and one‐third of the transection line of the stomach were dissected; finally the anterior wall suturing at the anastomotic site was performed by the laparoscopic hand‐sewn technique. Discussion SHS procedure was performed for 17 gastric cancer patients. There were no intraoperative complications or conversions to open surgery. One intra‐abdominal abscess was observed although there was no anastomotic leakage. The median reconstruction time was 48 minutes (32‐63). The SHS procedure was safe, feasible, and economical, although it requires sufficient laparoscopic suturing and ligation skill. [ABSTRACT FROM AUTHOR]

Published
2021
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109. A case of esophageal cancer with an aberrant right subclavian artery treated with mediastinoscopic esophagectomy.

Author

Hashimoto, Masashi, Shirakawa, Yasuhiro, Maeda, Naoaki, Tanabe, Shunsuke, Sakurama, Kazufumi, Noma, Kazuhiro, and Fujiwara, Toshiyoshi

Subjects
SUBCLAVIAN artery, ESOPHAGECTOMY, OPERATIVE surgery, ESOPHAGEAL cancer, LYMPHADENECTOMY, LARYNGEAL nerves
Abstract

An aberrant right subclavian artery (ARSA) is one of the famous anatomical abnormalities with a prevalence of 0.16–4.4%. In esophagectomy, anatomical abnormalities of the ARSA could cause complications with some surgical procedures. An 85‐year old man was referred to our department for esophageal adenocarcinoma that was at a slightly high position for esophagectomy with the abdominal approach. However, he had a significant past medical history. This risk factor made it difficult to perform thoracoscopic esophagectomy. He underwent mediastinoscopic esophagectomy (ME) with the left cervical and laparoscopic approach. The ARSA presented no difficulties with the ME surgical technique including the dissection of the left recurrent laryngeal nerve lymph node. Although this patient had a respiratory dysfunction and some difficulties in a prone position, ME enabled a safe esophagectomy with lymph node dissection. [ABSTRACT FROM AUTHOR]

Published
2021
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110. Abstract CT185: Phase I dose-escalation study of endoscopic intratumoral injection of OBP-301 (telomelysin) with radiotherapy in esophageal cancer patients unfit for standard treatments

Author

Fujiwara, Toshiyoshi, primary, Tanabe, Shunsuke, additional, Tazawa, Hiroshi, additional, Kanaya, Nobuhiko, additional, Noma, Kazuhiro, additional, Kagawa, Shunsuke, additional, Kuroda, Shinji, additional, Urata, Yasuo, additional, and Shirakawa, Yasuhiro, additional

Published
2019
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111. Abstract 1155: Stemness control by iron chelator is a novel therapeutic strategy for esophageal cancer

Author

Narusaka, Toru, primary, Ohara, Toshiaki, additional, Noma, Kazuhiro, additional, Katsura, Yuki, additional, Nishiwaki, Noriyuki, additional, Tabuchi, Motoyasu, additional, Fushimi, Takuro, additional, Ogawa, Toshihiro, additional, Takeda, Sho, additional, Komoto, Satoshi, additional, Sato, Hiroaki, additional, Kikuchi, Satoru, additional, Tomono, Yasuko, additional, Tazawa, Hiroshi, additional, Kagawa, Shunsuke, additional, Shirakawa, Yasuhiro, additional, and Fujiwara, Toshiyoshi, additional

Published
2019
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112. Abstract 2979: Boosting replication and penetration of telomerase-specific replicative virus by paclitaxel induces synthetic lethality in peritoneal metastasis of gastric cancer

Author

Ogawa, Toshihiro, primary, Kikuchi, Satoru, additional, Ishikawa, Wataru, additional, Tazawa, Hiroshi, additional, Tabuchi, Motoyasu, additional, Kuroda, Shinji, additional, Noma, Kazuhiro, additional, Nishizaki, Masahiko, additional, Kagawa, Shunsuke, additional, Urata, Yasuo, additional, and Fujiwara, Toshiyoshi, additional

Published
2019
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113. Abstract LB-310: Overcoming resistance of conventional therapies by targeting cancer-associated fibroblasts (CAFs) with near-infrared photoimmunotherapy (NIR-PIT)

Author

Komoto, Satoshi, primary, Noma, Kazuhiro, additional, Katsube, Ryoichi, additional, Kato, Takuya, additional, Ohara, Toshiaki, additional, Sato, Hiroaki, additional, Narusaka, Toru, additional, Nisiwaki, Noriyuki, additional, Tazawa, Hiroshi, additional, Shirakawa, Yasuhiro, additional, and Fujiwara, Toshiyoshi, additional

Published
2019
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114. Abstract 4330: Activation ofAZIN1RNA editing facilitates and promotes invasive potential of cancer associated fibroblasts in colorectal cancer

Author

Takeda, Sho, primary, Shigeyasu, Kunitoshi, additional, Okugawa, Yoshinaga, additional, Yoshida, Kazuhiro, additional, Mori, Yoshiko, additional, Yano, Shuya, additional, Noma, Kazuhiro, additional, Umeda, Yuzo, additional, Kondo, Yoshitaka, additional, Kishimoto, Hiroyuki, additional, Teraishi, Fuminori, additional, Tazawa, Hiroshi, additional, Kagawa, Shunsuke, additional, Goel, Ajay, additional, and Fujiwara, Toshiyoshi, additional

Published
2019
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115. Photoimmunotherapy for cancer-associated fibroblasts targeting fibroblast activation protein in human esophageal squamous cell carcinoma

Author

Watanabe, Shinichiro, primary, Noma, Kazuhiro, additional, Ohara, Toshiaki, additional, Kashima, Hajime, additional, Sato, Hiroaki, additional, Kato, Takuya, additional, Urano, Shinichi, additional, Katsube, Ryoichi, additional, Hashimoto, Yuuri, additional, Tazawa, Hiroshi, additional, Kagawa, Shunsuke, additional, Shirakawa, Yasuhiro, additional, Kobayashi, Hisataka, additional, and Fujiwara, Toshiyoshi, additional

Published
2019
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116. Activation of AZIN1 RNA editing is a novel mechanism that promotes invasive potential of cancer-associated fibroblasts in colorectal cancer

Author

Takeda, Sho, primary, Shigeyasu, Kunitoshi, additional, Okugawa, Yoshinaga, additional, Yoshida, Kazuhiro, additional, Mori, Yoshiko, additional, Yano, Shuya, additional, Noma, Kazuhiro, additional, Umeda, Yuzo, additional, Kondo, Yoshitaka, additional, Kishimoto, Hiroyuki, additional, Teraishi, Fuminori, additional, Nagasaka, Takeshi, additional, Tazawa, Hiroshi, additional, Kagawa, Shunsuke, additional, Fujiwara, Toshiyoshi, additional, and Goel, Ajay, additional

Published
2019
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117. A Novel Combination Cancer Therapy with Iron Chelator Targeting Cancer Stem Cells via Suppressing Stemness

Author

Katsura, Yuki, primary, Ohara, Toshiaki, additional, Noma, Kazuhiro, additional, Ninomiya, Takayuki, additional, Kashima, Hajime, additional, Kato, Takuya, additional, Sato, Hiroaki, additional, Komoto, Satoshi, additional, Narusaka, Toru, additional, Tomono, Yasuko, additional, Xing, Boyi, additional, Chen, Yuehua, additional, Tazawa, Hiroshi, additional, Kagawa, Shunsuke, additional, Shirakawa, Yasuhiro, additional, Kasai, Tomonari, additional, Seno, Masaharu, additional, Matsukawa, Akihiro, additional, and Fujiwara, Toshiyoshi, additional

Published
2019
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119. Cancer-associated fibroblasts (CAFs) promote the lymph node metastasis of esophageal squamous cell carcinoma

Author

Kashima, Hajime, primary, Noma, Kazuhiro, additional, Ohara, Toshiaki, additional, Kato, Takuya, additional, Katsura, Yuki, additional, Komoto, Satoshi, additional, Sato, Hiroaki, additional, Katsube, Ryoichi, additional, Ninomiya, Takayuki, additional, Tazawa, Hiroshi, additional, Shirakawa, Yasuhiro, additional, and Fujiwara, Toshiyoshi, additional

Published
2018
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120. Identifying the needs for teaching fundamental knowledge of laparoscopic surgery: a cross-sectional study in Japan

Author

Yokoyama, Shinichiro, primary, Watanabe, Yusuke, additional, Kurashima, Yo, additional, Oshita, Akihiko, additional, Nishizawa, Yuji, additional, Naitoh, Takeshi, additional, Nakamura, Fumitaka, additional, Kikuchi, Satoru, additional, Noma, Kazuhiro, additional, Poudel, Saseem, additional, Suzuki, Akihiro, additional, Nishihara, Yuichi, additional, Ito, Masaaki, additional, and Hirano, Satoshi, additional

Published
2018
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121. Multicenter retrospective study to evaluate the efficacy and safety of the double-flap technique as antireflux esophagogastrostomy after proximal gastrectomy (rD-FLAP Study)

Author

Kuroda, Shinji, primary, Choda, Yasuhiro, additional, Otsuka, Shinya, additional, Ueyama, Satoshi, additional, Tanaka, Norimitsu, additional, Muraoka, Atsushi, additional, Hato, Shinji, additional, Kimura, Toshikazu, additional, Tanakaya, Kohji, additional, Kikuchi, Satoru, additional, Tanabe, Shunsuke, additional, Noma, Kazuhiro, additional, Nishizaki, Masahiko, additional, Kagawa, Shunsuke, additional, Shirakawa, Yasuhiro, additional, Kamikawa, Yasuaki, additional, and Fujiwara, Toshiyoshi, additional

Published
2018
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122. Cancer-Associated Fibroblasts Affect Intratumoral CD8+ and FoxP3+ T Cells Via IL6 in the Tumor Microenvironment

Author

Kato, Takuya, primary, Noma, Kazuhiro, additional, Ohara, Toshiaki, additional, Kashima, Hajime, additional, Katsura, Yuki, additional, Sato, Hiroaki, additional, Komoto, Satoshi, additional, Katsube, Ryoichi, additional, Ninomiya, Takayuki, additional, Tazawa, Hiroshi, additional, Shirakawa, Yasuhiro, additional, and Fujiwara, Toshiyoshi, additional

Published
2018
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129. Abstract 5066: Dual-targeting photoimmunotherapy (NIR-PIT) for esophageal cancer cells and cancer-associated fibroblasts (CAFs)

Author

Sato, Hiroaki, primary, Noma, Kazuhiro, additional, Narusaka, Toru, additional, Komoto, Satoshi, additional, Katsura, Yuki, additional, Kato, Takuya, additional, Ninomiya, Takayuki, additional, Ohara, Toshiaki, additional, Tazawa, Hiroshi, additional, Shirakawa, Yasuhiro, additional, Kobayashi, Hisataka, additional, and Fujiwara, Toshiyoshi, additional

Published
2018
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130. Abstract 4807: Novel theranostic strategy against peritoneal metastasis of scirrhous gastric cancer: Combination with fluorescence oncolytic adenovirus and chemotherapy

Author

Ishikawa, Wataru, primary, Kikuchi, Satoru, additional, Tazawa, Hiroshi, additional, Ohara, Toshiaki, additional, Kuroda, Shinji, additional, Noma, Kazuhiro, additional, Kishimoto, Hiroyuki, additional, Nishizaki, Masahiko, additional, Urata, Yasuo, additional, Kagawa, Shunsuke, additional, and Fujiwara, Toshiyoshi, additional

Published
2018
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132. Abstract 2033: Transforming growth factor-b-induced epithelial-mesenchymal transition is attenuated by telomerase-specific oncolytic virotherapy in human esophageal cancer

Author

Masuda, Tomoya, primary, Tazawa, Hiroshi, additional, Ieda, Takeshi, additional, Hashimoto, Yuuri, additional, Tanabe, Shunsuke, additional, Noma, Kazuhiro, additional, Urata, Yasuo, additional, Kagawa, Shunsuke, additional, Shirakawa, Yasuhiro, additional, and Fujiwara, Toshiyoshi, additional

Published
2018
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133. Abstract LB-045: Iron depletion suppress the stemness markers and functions of cancer stem cells

Author

Ohara, Toshiaki, primary, Katsura, Yuki, additional, Noma, Kazuhiro, additional, Narusaka, Toru, additional, Kato, Takuya, additional, Sato, Hiroaki, additional, Komoto, Satoshi, additional, Tomono, Yasuko, additional, Ninomiya, Takayuki, additional, Tazawa, Hiroshi, additional, Kagawa, Shunsuke, additional, Shirakawa, Yasuhiro, additional, and Fujiwara, Toshiyoshi, additional

Published
2018
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134. Abstract 1101: Visualization of epithelial-mesenchymal transition in inflammatory microenvironment-colorectal cancer network in vitro and in vivo

Author

Tazawa, Hiroshi, primary, Ieda, Takeshi, additional, Yano, Shuya, additional, Kikuchi, Satoru, additional, Kuroda, Shinji, additional, Ohara, Toshiaki, additional, Noma, Kazuhiro, additional, Kishimoto, Hiroyuki, additional, Nishizaki, Masahiko, additional, Kagawa, Shunsuke, additional, Saitou, Takashi, additional, Imamura, Takeshi, additional, and Fujiwara, Toshiyoshi, additional

Published
2018
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135. Iron depletion is a novel therapeutic strategy to target cancer stem cells

Author

Ninomiya, Takayuki, primary, Ohara, Toshiaki, additional, Noma, Kazuhiro, additional, Katsura, Yuki, additional, Katsube, Ryoichi, additional, Kashima, Hajime, additional, Kato, Takuya, additional, Tomono, Yasuko, additional, Tazawa, Hiroshi, additional, Kagawa, Shunsuke, additional, Shirakawa, Yasuhiro, additional, Kimura, Fumiaki, additional, Chen, Ling, additional, Kasai, Tomonari, additional, Seno, Masaharu, additional, Matsukawa, Akihiro, additional, and Fujiwara, Toshiyoshi, additional

Published
2017
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136. Abstract 5809: Fluorescence-guided spatiotemporal dynamics of epithelial-mesenchymal transition under inflammatory microenvironment during colorectal cancer progression

Author

Ieda, Takeshi, primary, Tazawa, Hiroshi, additional, Kikuchi, Satoru, additional, Kuroda, Shinji, additional, Ohara, Toshiaki, additional, Noma, Kazuhiro, additional, Kishimoto, Hiroyuki, additional, Nagasaka, Takeshi, additional, Nishizaki, Masahiko, additional, Kagawa, Shunsuke, additional, Imamura, Takeshi, additional, and Fujiwara, Toshiyoshi, additional

Published
2017
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137. Abstract 925: Tumorigenesis of murine iPS cell is prevented by iron depletion with downregulation of stemness markers

Author

Katsura, Yuki, primary, Ohara, Toshiaki, additional, Kashima, Hajime, additional, Sato, Hiroaki, additional, Kato, Takuya, additional, Ninomiya, Takayuki, additional, Noma, Kazuhiro, additional, Tomono, Yasuko, additional, Tazawa, Hiroshi, additional, Kagawa, Shunsuke, additional, Shirakawa, Yasuhiro, additional, and Fujiwara, Toshiyoshi, additional

Published
2017
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140. Abstract 1103: Novel theranostic strategy against scirrhous gastric cancer; combination of chemotherapy and fluorescence oncolytic adenovirus

Author

Ishikawa, Wataru, primary, Kikuchi, Satoru, additional, Tazawa, Hiroshi, additional, Kuroda, Shinji, additional, Noma, Kazuhiro, additional, Kishimoto, Hiroyuki, additional, Nagasaka, Takeshi, additional, Nishizaki, Masahiko, additional, Kagawa, Shunsuke, additional, and Fujiwara, Toshiyoshi, additional

Published
2017
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142. Achalasia treated with per-oral endoscopic myotomy (POEM)

Author

Sugihara, Yuusaku, primary, Harada, Keita, additional, Kato, Ryo, additional, Yamauchi, Kenji, additional, Takashima, Shiho, additional, Takei, Daisuke, additional, Inokuchia, Toshihiro, additional, Takahara, Masahiro, additional, Kawano, Seiji, additional, Hiraoka, Sakiko, additional, Tanabe, Shunsuke, additional, Noma, Kazuhiro, additional, Shirakawa, Yasuhiro, additional, Manabe, Noriaki, additional, Inoue, Haruhiro, additional, and Okada, Hiroyuki, additional

Published
2017
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143. Cancer‐associated fibroblasts (CAFs) promote the lymph node metastasis of esophageal squamous cell carcinoma.

Author

Kashima, Hajime, Noma, Kazuhiro, Ohara, Toshiaki, Kato, Takuya, Katsura, Yuki, Komoto, Satoshi, Sato, Hiroaki, Katsube, Ryoichi, Ninomiya, Takayuki, Tazawa, Hiroshi, Shirakawa, Yasuhiro, and Fujiwara, Toshiyoshi

Abstract

Lymph node metastasis is a pathognomonic feature of spreading tumors, and overcoming metastasis is a challenge in attaining more favorable clinical outcomes. Esophageal cancer is an aggressive tumor for which lymph node metastasis is a strong poor prognostic factor, and the tumor microenvironment (TME), and cancer‐associated fibroblasts (CAFs) in particular, has been implicated in esophageal cancer progression. CAFs play a central role in the TME and have been reported to provide suitable conditions for the progression of esophageal cancer, similar to their role in other malignancies. However, little is known concerning the relevance of CAFs to the lymph node metastasis of esophageal cancer. Here, we used clinical samples of esophageal cancer to reveal that CAFs promote lymph node metastasis and subsequently verified the intercellular relationships in vitro and in vivo using an orthotopic metastatic mouse model. In the analysis of clinical samples, FAP+ CAFs were strongly associated with lymph node metastasis rather than with other prognostic factors. Furthermore, CAFs affected the ability of esophageal cancer cells to acquire metastatic phenotypes in vitro; this finding was confirmed by data from an in vivo orthotopic metastatic mouse model showing that the number of lymph node metastases increased upon injection of cocultured cancer cells and CAFs. In summary, we verified in vitro and in vivo that the accumulation of CAFs enhances the lymph node metastasis of ESCC. Our data suggest that CAF targeted therapy can reduce lymph node metastasis and improve the prognosis of patients with esophageal cancer in the future. What's new? When fighting a tumor, targeting the tumor microenvironment can be more effective than hitting the tumor itself. To study lymph node metastasis in esophageal cancer, these authors tested clinical samples to evaluate expression of fibroblast‐activation protein (FAP) by cancer‐associated fibroblasts in the tumor stroma. The more FAP‐positive CAFs, the greater the likelihood of lymph node metastasis, they found. Next, they tested the effect in vivo. Mice injected with FAP‐positive CAFs developed far more metastases than their control counterparts. Targeting CAFs may improve prognosis and reduce lymph node metastasis in esophageal cancer. [ABSTRACT FROM AUTHOR]

Published
2019
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144. Multicenter retrospective study to evaluate the efficacy and safety of the double‐flap technique as antireflux esophagogastrostomy after proximal gastrectomy (rD‐FLAP Study).

Author

Kuroda, Shinji, Choda, Yasuhiro, Otsuka, Shinya, Ueyama, Satoshi, Tanaka, Norimitsu, Muraoka, Atsushi, Hato, Shinji, Kimura, Toshikazu, Tanakaya, Kohji, Kikuchi, Satoru, Tanabe, Shunsuke, Noma, Kazuhiro, Nishizaki, Masahiko, Kagawa, Shunsuke, Shirakawa, Yasuhiro, Kamikawa, Yasuaki, and Fujiwara, Toshiyoshi

Subjects
GASTROESOPHAGEAL reflux treatment, SURGICAL flaps, GASTROSTOMY, GASTRECTOMY, SURGICAL anastomosis
Abstract

Aim: As a result of the difficulty in effective prevention of gastroesophageal reflux, no standard reconstruction procedure after proximal gastrectomy (PG) has yet been established. The double‐flap technique (DFT), or Kamikawa procedure, is an antireflux reconstruction procedure in esophagogastrostomy. The efficacy of DFT has recently been reported in several studies. However, these were all single‐center studies with a limited number of cases. Methods: We conducted a multicenter retrospective study in which patients who underwent DFT, irrespective of disease type and reconstruction approach, at each participating institution between 1996 and 2015 were registered. Primary endpoint was incidence of reflux esophagitis at 1‐year after surgery, and secondary endpoint was incidence of anastomosis‐related complications. Results: Of 546 patients who were eligible for this study, 464 patients who had endoscopic examination at 1‐year follow up were evaluated for reflux esophagitis. Incidence of reflux esophagitis of all grades was 10.6% and that of grade B or higher was 6.0%. Male gender and anastomosis located in the mediastinum/intra‐thorax were independent risk factors for grade B or higher reflux esophagitis (odds ratio [OR]: 4.21, 95% confidence interval [CI]: 1.44‐10.9, P = 0.0109). Total incidence of anastomosis‐related complications was 7.2%, including leakage in 1.5%, strictures in 5.5% and bleeding in 0.6% of cases. Laparoscopic reconstruction was the only independent risk factor for anastomosis‐related complications (OR: 3.93, 95% CI: 1.93‐7.80, P = 0.0003). Conclusion: Double‐flap technique might be a feasible option after PG for effective prevention of reflux, although anastomotic stricture is a complication that must be well‐prepared for. A multicenter retrospective study in which 546 patients who underwent the double‐flap technique (DFT), irrespective of disease type and reconstruction approach, at each participating institution between 1996 and 2015 were registered, showed that the incidence of reflux esophagitis of all grades was 10.6% and that of grade B or higher was 6.0%, and the total incidence of anastomosis‐related complications was 7.2%, including leakage in 1.5%, strictures in 5.5% and bleeding in 0.6% of cases. DFT might be a feasible option after proximal gastrectomy for effective prevention of reflux, although anastomotic stricture is a complication that must be well‐prepared for. [ABSTRACT FROM AUTHOR]

Published
2019
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145. Assistant-based standardization of prone position thoracoscopic esophagectomy

Author

Shirakawa, Yasuhiro, Noma, Kazuhiro, Maeda, Naoaki, Katsube, Ryoichi, Tanabe, Shunsuke, Ohara, Toshiaki, Sakurama, Kazufumi, and Fujiwara, Toshiyoshi

Subjects
standardization, Male, Surgeons, Esophageal Neoplasms, Thoracoscopy, Operative Time, thoracoscopic esophagectomy, Adenocarcinoma, Middle Aged, Patient Positioning, Carcinoma, Neuroendocrine, Esophagectomy, Postoperative Complications, Lymphatic Metastasis, Carcinoma, Squamous Cell, Prone Position, Humans, Lymph Node Excision, Female, Ergonomics, Aged
Abstract

Thoracoscopic esophagectomy in the prone position (TEPP) might enable solo-surgery in cases requiring resection of the esophagus and the surrounding lymph nodes due to the associated advantages of good exposure of the surgical field and ergonomic considerations for the surgeon. However, no one approach can be for all patients requiring extensive lymphadenectomy. We recently developed an assistant-based procedure to standardize exposure of the surgical field. Patients were divided into 1 of 2 groups:a pre-standardization group (n=37) and a post-standardization group (n=28). The thoracoscopic operative time was significantly shorter (p=0.0037) in the post-standardization group (n=28; 267 ± 31 min) than in the pre-standardization group (n=37;301 ± 53 min). Further, learning curve analysis using the moving average method showed stabilization of the thoracoscopic operative time after the standardization. No significant differences were found in the number of mediastinal lymph nodes dissected or intraoperative blood loss between the 2 groups. There were also no significant differences in the complication rate. Assistant-based surgery and standardization of the procedure resulted in a well-exposed and safe surgical field. TEPP decreased the operative time, even in patients requiring extensive lymphadenectomy.

Published
2014

146. Nonexposure laparoscopic and endoscopic cooperative surgery (closed laparoscopic and endoscopic cooperative surgery) for gastric submucosal tumor

Author

Kikuchi, Satoru, primary, Nishizaki, Masahiko, additional, Kuroda, Shinji, additional, Tanabe, Shunsuke, additional, Noma, Kazuhiro, additional, Kagawa, Shunsuke, additional, Shirakawa, Yasuhiro, additional, Kato, Hiroshi, additional, Okada, Hiroyuki, additional, and Fujiwara, Toshiyoshi, additional

Published
2016
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148. Abstract 1560: Correlation of FAP(fibroblast activation protein)-expressing cancer associated fibroblasts (CAFs) and tumor metastasis in esophageal carcinoma

Author

Kashima, Hajime, primary, Noma, Kazuhiro, additional, Katsura, Yuki, additional, Kato, Takuya, additional, Katsube, Ryoichi, additional, Ninomiya, Takayuki, additional, Ohara, Toshiaki, additional, Tazawa, Hiroshi, additional, Kagawa, Shunsuke, additional, Shirakawa, Yasuhiro, additional, and Fujiwara, Toshiyoshi, additional

Published
2016
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149. Abstract 4160: Prognostic correlation of tumor-infiltrating lymphocytes (TILs) and cancer associated fibroblasts (CAFs) in patients with human esophageal carcinoma

Author

Kato, Takuya, primary, Noma, Kazuhiro, additional, Katsura, Yuki, additional, Kashima, Hajime, additional, Ninomiya, Takayuki, additional, Ohara, Toshiaki, additional, Tazawa, Hiroshi, additional, Kagawa, Shunsuke, additional, Shirakawa, Yasuhiro, additional, and Fujiwara, Toshiyoshi, additional

Published
2016
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150. Abstract 1613: A novel live imaging system for inflammation-induced epithelial-mesenchymal transition in colorectal cancers

Author

Ieda, Takeshi, primary, Tazawa, Hiroshi, additional, Kikuchi, Satoru, additional, Kuroda, Shinji, additional, Ohara, Toshiaki, additional, Noma, Kazuhiro, additional, Kishimoto, Hiroyuki, additional, Nagasaka, Takeshi, additional, Nishizaki, Masahiko, additional, Kagawa, Shunsuke, additional, and Fujiwara, Toshiyoshi, additional

Published
2016
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