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107. Prostate Cancer

Author

Nelson, William G., primary, Carter, H. Ballentine, additional, DeWeese, Theodore L., additional, Antonarakis, Emmanuel S., additional, and Eisenberger, Mario A., additional

Published
2014
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109. Contributors

Author

Abbruzzese, James L., primary, Abou-Alfa, Ghassan K., additional, Abrahm, Janet L., additional, Abrams, Jeffrey S., additional, Aisner, Dara L., additional, Alanee, Shaheen, additional, Alberts, Steven R., additional, Alonso-Basanta, Michelle, additional, Anderson, Megan E., additional, Antonarakis, Emmanuel S., additional, Appelbaum, Frederick R., additional, Ashman, Jonathan B., additional, Aylward, Juliet L., additional, Baaj, Ali A., additional, Balar, Arjun V., additional, Balducci, Lodovico, additional, Bartlett, Nancy L., additional, Bashir, Qaiser, additional, Beaupin, Lynda Kwon, additional, Benson, Al B., additional, Berkowitz, Ross Stuart, additional, Berry, Donald A., additional, Bevers, Therese B., additional, Boggess, John F., additional, Bohman, Leif-Erik, additional, Borowitz, Michael J., additional, Boyd, Jeff, additional, Brahmer, Julie R., additional, Brell, Joanna M., additional, Brown, Karen, additional, Brown, Powel H., additional, Bunn, Paul A., additional, Byrd, John C., additional, Campana, Dario, additional, Carbone, David P., additional, Carter, H. Ballentine, additional, Castillo, Jorge J., additional, Chadha, Manpreet K., additional, Champlin, Richard, additional, Chang, Alfred E., additional, Chanock, Stephen J., additional, Chauhan, Vikash P., additional, Chen, Herbert, additional, Chen, Ronald C., additional, Cheung, Nai-Kong V., additional, Christian, Michaele C., additional, Cinciripini, Paul M., additional, Clarke, Michael F., additional, Cmelak, Anthony J., additional, Coleman, Robert E., additional, Collins, Jerry M., additional, Coombes, Kevin R., additional, Cortes, Jorge, additional, Costa, Mauro W., additional, Covey, Anne, additional, Cowan, Kenneth H., additional, Culkin, Daniel J., additional, Czito, Brian G., additional, Dalerba, Piero, additional, Dalmau, Josep, additional, D'Angelica, Michael, additional, Davidson, Nancy E., additional, DeWeese, Theodore L., additional, Dickson, Mark, additional, Diehn, Maximilian, additional, Digumarthy, Subba R., additional, Dispenzieri, Angela, additional, Domchek, Susan M., additional, Dome, Jeffrey S., additional, Donohue, John H., additional, Doroshow, James H., additional, Dorsey, Jay F., additional, Doyon, Laura, additional, Drapkin, Ronny, additional, Duda, Dan G., additional, Duska, Linda R., additional, Eisenberg, Rosana, additional, Eisenberger, Mario A., additional, Erler, Janine, additional, Fashoyin-Aje, Lola A., additional, Fearon, Eric R., additional, Fecher, Leslie A., additional, Flynn, Joseph M., additional, Ford, James M., additional, Forde, Patrick M., additional, Forastiere, Arlene A., additional, Forsythe, Laura P., additional, Foyil, Kelley V., additional, Franklin, Wilbur A., additional, Freifeld, Alison G., additional, Friedlander, Terence W., additional, Friedman, Debra L., additional, Fuller, Arlan F., additional, Galluzzi, Lorenzo, additional, Gangadhar, Tara C., additional, Garcia, Marileila Varella, additional, Gebhardt, Mark C., additional, Giaccia, Amato J., additional, Gilbert, Mark R., additional, Gius, David, additional, Glaspy, John, additional, Gokaslan, Ziya L., additional, Goldstein, Donald Peter, additional, Goodman, Anne Kathryn, additional, Goodman, Karyn A., additional, Greenstein, Adrian, additional, Greenstein, Alexander, additional, Gritz, Ellen R., additional, Gross, Thomas G., additional, Grossman, Stuart A., additional, Gulick, Roy M., additional, Gunderson, Leonard L., additional, Haik, Barrett G., additional, Hainsworth, John D., additional, Haithcock, Benjamin E., additional, Hallemeier, Christopher L., additional, Hanrahan, Aphrothiti J., additional, Hawk, Ernest T., additional, Heinlen, Jonathan E., additional, Helman, Lee J., additional, Herman, Joseph M., additional, Higgins, H. William, additional, Ho, Alan L., additional, Holen, Ingunn, additional, Hollander, Andrew B., additional, Horn, Leora, additional, Howard, Scott C., additional, Ito, Fumito, additional, Iyer, Gopa, additional, Jaffe, Elaine S., additional, Jaffee, Elizabeth M., additional, Jain, Rakesh K., additional, Jarnagin, William, additional, Jaroszewski, Dawn E., additional, Jatoi, Aminah, additional, Jaume, Juan C., additional, Jhingran, Anuja, additional, Johnson, David H., additional, Johnston, Brian, additional, Johnston, Patrick G., additional, Jones, Lee W., additional, Judy, Kevin D., additional, Kachnic, Lisa A., additional, Kamin, Deborah Y., additional, Kantarjian, Hagop, additional, Karakousis, Giorgos, additional, Karam-Hage, Maher, additional, Karcioglu, Zeynel A., additional, Kased, Norbert, additional, Kastan, Michael B., additional, Katz, Stuart, additional, Kauffman, Eric, additional, Kaul, Daniel R., additional, Kelly, Ronan, additional, Kemeny, Nancy, additional, Kensler, Thomas W., additional, Kent, Erin E., additional, Kepp, Oliver, additional, Kilgore, Joshua E., additional, Kim, Ellen, additional, Kimmelshue, Katherine N., additional, Kleinberg, Lawrence, additional, Kobrinsky, Boris, additional, Kroemer, Guido, additional, Kummar, Shivaani, additional, Laheru, Daniel A., additional, Lambert, Paul F., additional, Laskin, Janessa, additional, Lawler, Mark, additional, Lee, Jack, additional, Lee, John Y.K., additional, Lee, Kachiu, additional, Lee, Nancy Y., additional, Lee, Susanna I., additional, Lenzi, Renato, additional, Lichter, Allen S., additional, Lipton, Allan, additional, Loprinzi, Charles L., additional, Loughlin, Paula, additional, Lowery, Maeve, additional, Lubner, Sam J., additional, Ludwig, Emmy, additional, Lustig, Robert A., additional, Machtay, Mitchell, additional, Macyszyn, Lukasz, additional, Mahvi, David M., additional, Maity, Amit, additional, Maki, Robert G., additional, Malumbres, Marcos, additional, Mansour, John C., additional, Massion, Pierre P., additional, Maresso, Karen Colbert, additional, Mauro, Lauren A., additional, Mayer, R. Samuel, additional, Mazeh, Haggi, additional, McCormick, Beryl, additional, McDonald, Charles J., additional, Meranze, Steven, additional, Miller, Chris J., additional, Milowsky, Matthew I., additional, Minsky, Bruce, additional, Mooney, Margaret, additional, Morgan, Mark, additional, Morton, A. Ross, additional, Murgo, Anthony J., additional, Nabati, Lida, additional, Nelson, William G., additional, Nesbit, Suzanne, additional, Niederhuber, John E., additional, Noy, Ariela, additional, O'Connor, Tracey, additional, Offit, Kenneth, additional, Onciu, Mihaela, additional, O'Reilly, Eileen M., additional, Ostrander, Elaine A., additional, Palefsky, Joel, additional, Pappas-Taffer, Lisa, additional, Pardoll, Drew, additional, Park, Jae H., additional, Phillips, Peter C., additional, Pili, Roberto, additional, Pinto, Peter A., additional, Post, Miriam D., additional, Pruitt, Amy A., additional, Pui, Ching-Hon, additional, Putnam, Joe Bill, additional, Querfeld, Christiane, additional, Raber, Martin N., additional, Rabius, Vance, additional, Rais-Bahrami, Soroush, additional, Rajkumar, S. Vincent, additional, Randall, R. Lor, additional, Rankin, Erinn B., additional, Riaz, Nadeem, additional, Ripley, R. Taylor, additional, Rizack, Tina, additional, Robinson, Clifford G., additional, Robinson, Jason D., additional, Robinson-Bostom, Leslie, additional, Rodriguez-Galindo, Carlos, additional, Rodriguez, Ronald, additional, Romesser, Paul B., additional, Roschewski, Mark J., additional, Rosen, Steven T., additional, Rosenfeld, Myrna R., additional, Rosenthal, Nadia, additional, Rowland, Julia H., additional, Rubenstein, James L., additional, Rubinstein, Paul G., additional, Rusch, Valerie W., additional, Russell, Anthony H., additional, Ryan, Charles J., additional, Sacchini, Virgilio, additional, Salto-Tellez, Manuel, additional, Sandlund, John T., additional, Santana, Victor M., additional, Schneider, David F., additional, Schrader, Kasmintan A., additional, Schreiber, Eric C., additional, Schuchter, Lynn M., additional, Sciubba, Daniel M., additional, Seiden, Michael V., additional, Sharaf, Ravi, additional, Sharma, Neelesh, additional, Sherman, Karen L., additional, Shia, Jinru, additional, Sideras, Kostandinos, additional, Sigurdson, Elin R., additional, Small, Eric J., additional, Smith, Angela, additional, Sneed, Penny K., additional, Snow, Stephen N., additional, Solit, David B., additional, Speyer, James L., additional, Spiegelman, Vladimir, additional, Springfield, Dempsey S., additional, Spunt, Sheri L., additional, Steensma, David P., additional, Stier, Elizabeth, additional, Stinchcombe, Thomas E., additional, Stone, Richard M., additional, Stranne, Steven Kent, additional, Streiff, Michael B., additional, Strickland, Paul T., additional, Sugden, Bill, additional, Tallman, Martin S., additional, Talmadge, James E., additional, Tefferi, Ayalew, additional, Teng, Joyce M.C., additional, Tepper, Joel E., additional, Tobinai, Kensei, additional, Tomaszewski, Joseph E., additional, Torti, Frank, additional, Trump, Donald L., additional, Tsukasaki, Kunihiro, additional, Schaeybroeck, Sandra Van, additional, Vanness, Erin, additional, Varadhachary, Gauri R., additional, Vardiman, James, additional, Vonderheide, Robert, additional, Wahl, Richard L., additional, Wang, Jean S., additional, Watanabe, Toshiki, additional, Weissman, Irving L., additional, White, Jeffrey D., additional, Wilson, Richard, additional, Wilson, Wyndham H., additional, Wolff, Antonio C., additional, Wong, Richard J., additional, Wood, Gary S., additional, Xu, George, additional, Xu, Yaohui Gloria, additional, Yang, Stephen, additional, Yee, John, additional, Yust-Katz, Shlomit, additional, Zagar, Timothy M., additional, Zeidan, Amer M., additional, Zeman, Elaine M., additional, Zhang, Longzhen, additional, Zheng, Haoyi, additional, and Zwiebel, James A., additional

Published
2014
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110. GSTP1 positive prostatic adenocarcinomas are more common in Black than White men in the United States

Author

Vidal, Igor, primary, Zheng, Qizhi, additional, Hicks, Jessica L., additional, Chen, Jiayu, additional, Platz, Elizabeth A., additional, Trock, Bruce J., additional, Kulac, Ibrahim, additional, Baena-Del Valle, Javier A., additional, Sfanos, Karen S., additional, Ernst, Sarah, additional, Jones, Tracy, additional, Maynard, Janielle P., additional, Glavaris, Stephanie A., additional, Nelson, William G., additional, Yegnasubramanian, Srinivasan, additional, and De Marzo, Angelo M., additional

Published
2021
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111. Resistance to androgen receptor signaling inhibition does not necessitate development of neuroendocrine prostate cancer

Author

Brennen, W. Nathaniel, primary, Zhu, Yezi, additional, Coleman, Ilsa M., additional, Dalrymple, Susan L., additional, Antony, Lizamma, additional, Patel, Radhika A., additional, Hanratty, Brian, additional, Chikarmane, Roshan, additional, Meeker, Alan K., additional, Zheng, S. Lilly, additional, Hooper, Jody E., additional, Luo, Jun, additional, De Marzo, Angelo M., additional, Corey, Eva, additional, Xu, Jianfeng, additional, Yegnasubramanian, Srinivasan, additional, Haffner, Michael C., additional, Nelson, Peter S., additional, Nelson, William G., additional, Isaacs, William B., additional, and Isaacs, John T., additional

Published
2021
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116. 81 - Prostate Cancer

Author

Nelson, William G., Antonarakis, Emmanuel S., Carter, H. Ballentine, De Marzo, Angelo M., and DeWeese, Theodore L.

Published
2020
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117. Copy number analysis indicates monoclonal origin of lethal metastatic prostate cancer

Author

Liu, Wennuan, Laitinen, Sari, Khan, Sofia, Vihinen, Mauno, Kowalski, Jeanne, Yu, Guoqiang, Chen, Li, Ewing, Charles M., Eisenberger, Mario A., Carducci, Michael A., Nelson, William G., Yegnasubramanian, Srinivasan, Luo, Jun, Wang, Yue, Xu, Jianfeng, Isaacs, William B., Visakorpi, Tapio, and Bova, G. Steven

Subjects
DNA microarrays -- Usage, Genetic variation -- Research, Prostate cancer -- Development and progression, Prostate cancer -- Genetic aspects, Prostate cancer -- Research
Abstract

Many studies have shown that primary prostate cancers are multifocal [1-3] and are composed of multiple genetically distinct cancer cell clones [4-6]. Whether or not multiclonal primary prostate cancers typically give rise to multiclonal or monoclonal prostate cancer metastases is largely unknown, although studies at single chromosomal loci are consistent with the latter case. Here we show through a high-resolution genome-wide single nucleotide polymorphism and copy number survey that most, if not all, metastatic prostate cancers have monoclonal origins and maintain a unique signature copy number pattern of the parent cancer cell while also accumulating a variable number of separate subclonally sustained changes. We find no relationship between anatomic site of metastasis [7] and genomic copy number change pattern. Taken together with past animal and cytogenetic studies of metastasise and recent single-locus genetic data in prostate and other metastatic cancers [8-10] these data indicate that despite common genomic heterogeneity in primary cancers, most metastatic cancers arise from a single precursor cancer cell. This study establishes that genomic archeology of multiple anatomically separate metastatic cancers in individuals can be used to define the salient genomic features of a parent cancer clone of proven lethal metastatic phenotype., We isolated DNA from 94 anatomically separate cancer sites in 30 men who died from metastatic prostate cancer (Fig. 1a) and analyzed it by chromosomal metaphase-based comparative genomic hybridization (cCGH), [...]

Published
2009

118. Epigenetic and transcriptional analysis reveals a core transcriptional program conserved in clonal prostate cancer metastases

Author

Severson, Tesa M., primary, Zhu, Yanyun, additional, De Marzo, Angelo M., additional, Jones, Tracy, additional, Simons, Jonathan W., additional, Nelson, William G., additional, Yegnasubramanian, Srinivasan, additional, Freedman, Matthew L., additional, Wessels, Lodewyk, additional, Bergman, Andries M., additional, Haffner, Michael C., additional, and Zwart, Wilbert, additional

Published
2021
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119. Association of Serum Carotenoids and Retinoids with Intraprostatic Inflammation in Men without Prostate Cancer or Clinical Indication for Biopsy in the Placebo Arm of the Prostate Cancer Prevention Trial

Author

Chadid, Susan, primary, Song, Xiaoling, additional, Schenk, Jeannette M., additional, Gurel, Bora, additional, Lucia, M. Scott, additional, Thompson, Ian M., additional, Neuhouser, Marian L., additional, Goodman, Phyllis J., additional, Parnes, Howard L., additional, Lippman, Scott M., additional, Nelson, William G., additional, De Marzo, Angelo M., additional, and Platz, Elizabeth A., additional

Published
2021
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121. Tracking the clonal origin of lethal prostate cancer

Author

Haffner, Michael C., Mosbruger, Timothy, Esopi, David M., Fedor, Helen, Heaphy, Christopher M., Walker, David A., Adejola, Nkosi, Gürel, Meltem, Hicks, Jessica, Meeker, Alan K., Halushka, Marc K., Simons, Jonathan W., Isaacs, William B., De Marzo, Angelo M., Nelson, William G., and Yegnasubramanian, Srinivasan

Published
2013
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128. Genomic and phenotypic heterogeneity in prostate cancer

Author

Haffner, Michael C., primary, Zwart, Wilbert, additional, Roudier, Martine P., additional, True, Lawrence D., additional, Nelson, William G., additional, Epstein, Jonathan I., additional, De Marzo, Angelo M., additional, Nelson, Peter S., additional, and Yegnasubramanian, Srinivasan, additional

Published
2020
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129. Use of Aspirin and Statins in Relation to Inflammation in Benign Prostate Tissue in the Placebo Arm of the Prostate Cancer Prevention Trial

Author

Hurwitz, Lauren M., primary, Kulac, Ibrahim, additional, Gumuskaya, Berrak, additional, Valle, Javier A. Baena Del, additional, Benedetti, Ines, additional, Pan, Fan, additional, Liu, Jun O., additional, Marrone, Michael T., additional, Arnold, Kathryn B., additional, Goodman, Phyllis J., additional, Tangen, Catherine M., additional, Lucia, M. Scott, additional, Thompson, Ian M., additional, Drake, Charles G., additional, Isaacs, William B., additional, Nelson, William G., additional, De Marzo, Angelo M., additional, and Platz, Elizabeth A., additional

Published
2020
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131. Contributors

Author

Abdul-Hussein, Mustafa, Abhyankar, Sunil, Adam, Rodney D., Adams, Paul C., Adesanya, T.M. Ayodele, Agudelo Higuita, Nelson Iván, Ahmed, Omar G., Akst, Lee, Anderson, Kelley P., Andre, Paul, Anstead, Gregory M., Aring, Ann M., Armstrong, Cheryl A., Arshi, Arash, Avalos, Danny, Azar, Cecilio M., Azarbal, Amir, Baeseman, Zachary, Bailey, Justin, Bajaj, Mandeep, Bakhutashvili, Vladimer, Balagué, Federico, Banti, Matthew Michael, Barth, Bradley, Basello, Gina M., Bassaly, Renee, Bassily-Marcus, Adel, Baughn, Julie, Belakovskiy, Aleksandr, Ben-Ami, Ronen, Bencheqroun, Hassan, Bernstein, David I., Bernstein, Jonathan A., Beyer, Caroline, Biggerstaff, Kristin Schmid, Birt, Mitchell, Blum, William, Bolotin, Diana, Bonnema, Rachel A., Borenstein, David, Bossart, Christopher, Bowman, Deidra, Bragg, Dee Ann, Bragg, Scott, Brice, Sylvia L., Briggs, Allyson M., Brill, John, Brown, Rachel, Buckley, Peter F., Burns, Sarah, Byrd, Kenneth P., Cadavid, Diego, Caraccio, Thomas R., Carek, Peter J., Carrion, Andres F., Cass, Amanda S., Castell, Donald O., Catinella, Anthony P., Cayley, William E., Jr., Cerquozzi, Sonia, Cervera, Alvaro, Cetani, Filomena, Chamberlain, Rachel, Chan, Lawrence, Chan, Miriam, Chandramohan, Divya, Chang, Zenas, Chen, Jimmy, Chen, Lin Yee, Chihara, Shingo, Chitlur, Meera, Chohan, Saima, Christensen, Jacob, Chyu, Kuang-Yuh, Cigarroa, Joaquin E., Cleland, Paul, Cline, Matthew, Coates, Laura C., Colenbrander, August, Commins, Ryan, Conageski, Christine, Conly, John, Contini, Carlo, Cooper, Ashley, Cooper, Stacy, Cormier, Allison, Cunha, Burke A., Cunha, Cheston B., Curran, Thomas, Curry, Amy, Daines, Cori L., Damas, Oriana M., Damitz, Beth A., Datta, Nandini, Dattilo, Natalie C., Davaro, Raul, David, Kevin A., de Leon, André, de Leon, Tate, DeCastro, Alexei O., DeGeorge, Katharine C., DeLoughery, Thomas G., Deodhar, Atul, Desai, Urmi, Dessinioti, Clio, Diamond, Michael P., Dion, Christopher, Do, Catherine, Dobbs, Thomas, Donahue, Colleen A., Donnan, Geoffrey A., Dorsch, John N., Dougan, Michael, Douglas, Chad, Dowlatshahi, Dar, Dowler, Shannon, Drevets, Douglas, Dudley, Samuel C., Jr., Duggan, Peter R., Eagle, Kim A., Eck, Leigh M., El Atrouni, Wissam, Elston, Dirk M., Embil, John M., Epstein, Scott K., Evans, Susan, Evens, Andrew M., Fagan, J. Barry, Fairweather, Mark, Falk, Marni J., Faris, Anna, Faugno, Anthony J., III, Faust, Hilary, Fayssoux, Kinder, Feldman, Dorianne, Ferguson, Ian, Fife, Terry. D., Finley, David J., Firnhaber, Jonathon, Fisher, Lynn, Fisher, William E., Fleseriu, Maria, Fletcher, Donald, Foster, Jeffrey Michael, Frank, Jennifer, Freeman, Ellen W., Frenz, David A., Gaba, Ruchi, Gaines, Melissa, Garcia, Mark, Ghany, Marc G., George, Virgilio V., Ghazi, Muhammad Ahmad, Gibney, Geoffrey, Gilbert, Donald L., Gilchrist, Karissa, Gillaspie, Erin A., Gilotra, Tarvinder, Gladwin, Mark T., Gluckman, Stephen J., Goddard, Andrew W., Goerl, Kyle, Gold, Mark S., Goldstein, Amy, González-Fernández, Marlis, Goodwin, Gregory, Gosmanov, Aidar R., Gradoni, Luigi, Graham, Timothy P., Grant-Kels, Jane M., Grdinovac, Kristine, Greenberg, Leslie, Greene, William, Greensher, Joseph, Gregory, David, Greiwe, Justin, Hague, Melissa, Halder, Rebat, Hall, Alan M., Harris, Kari R., Harrison, Taylor B., Hartman, Adam L., Hayes, Erin, Haynes, James W., Heidelbaugh, Joel J., Hinshaw, Molly A., Hockenberry, Brandon, Hohl, Raymond J., Holguin, Therese, Holstein, Sarah A., Holyoak, Michael, Homan, Gretchen, Hommema, Kevin, Hommema, Laurie A.M., Horn, Leora, Hossani-Madani, Ahmad Reza, House, Steven A., Houssayni, Sarah, Hueston, William J., Huettemann, Richard, Huffstetler, Alison, Hunter, Anthony, Ibidapo-Obe, Oyetokunbo, Ing, Alice M., Irwin, Gretchen, Isaac, Daniel, Jackson, Alan C., Jackson-Tarlton, Caitlin, Jacobson, Kurt M., Jaller, Jose A., James, W. Ennis, Jeang, Lauren, Jha, Abhishek, Jia, Xiaoming, Johnson, Casey R., Johnson, Lisa M., Jolissaint, Joshua S., Judson, Marc A., Kadhiravan, Tamilarasu, Kalia, Rachna, Kamprath, Sagar, Kanter, Jessica Rachel, Karnad, Dilip R., Karnchanasorn, Rudruidee, Katsambas, Andreas, Katz, Ben, Katzman, Rebecca, Kaunitz, Andrew M., Keegan, B. Mark, Kellerman, Rick D., Kellermann, Scott, Kelly, Christina M., Khaki, Sheevaun, Kim, Arthur Y., Kim, Haejin, Kirsner, Robert S., Kiwalkar, Sonam, Knoefel, Janice, Kolb, Amanda, Kolla, Bhanu Prakash, Korley, Frederick, Kovalsky, Adrienne N., Krause, Megan, Kraut, Eric H., Krishnamurti, Lakshmanan, Krishnan, Kumar, Kuhlmann, Zachary, Kulkarni, Roshni, Kumar, Seema, Kwaan, Mary R., Kyle, Robert A., Lampton, Lucius M., Lange, Richard A., Langlois, Fabienne, Lau, Christine, Lawrence-Hylland, Susan, Lazaroff, Jake, Lee, Lydia U., Leikin, Jerrold B., Leikin, Scott, Leung, Alexander K.C., Levy-Clarke, Grace, LeWinter, Martin M., Lewis, Jennifer, Li, Ming, Liebenstein, Tyler, Lin, Albert P., Linder, Jeffrey A., Lock, James, Long, M. Chantel, Loo-Gross, Colleen, Lubsen, Julia R., Lun, Ronda, Mahvi, David (Sasha), Maiorella, RosaMarie, Malhotra, Uma, Manlove, Emily, Manson, JoAnn E., Mansukhani, Meghna, Marcocci, Claudio, Margo, Curtis E., Marker, Jason E., Martin, Paul, Mathis, Samuel E., Matson, Kristine, Matza, Mark A., Maxwell, Pinckney J., IV, May, Danica, Mazepa, Gregory Marshall, McClain, Molly, McGrew, Christopher, McGuigan, Christopher Charles, Mehta, Meetal, Meiselman, Mick S., Mercado, Moises, Merrell, Ryan, Meyers, Steven L., Michael, William, Miller, Brian J., Millington, Timothy M., Mirza, Moben, Mofenson, Howard C., Mogensen, Kris M., Moritz, Michael L., Mortada, Rami, Mortaji, Parisa, Moss, Heather E., Moul, Judd W., Muller, Martha, Murinova, Natalia E., Murphy, Michael, Muthusubramanian, Arjun, Nagji, Alykhan S., Naranjo, Laura, Nasim, Rabab, Nazari, Matthew A., Nazeef, Moniba, Neelakantan, Viswanathan K., Neff, Don, Neil, Tara, Nelson, William G., Neschis, David G., Nester, Theresa, Nguyen, Tam T., Nicol, Andrea L., Nieves-Arriba, Lucybeth, North, Crystal, Novac, Andrei, Novelli, Enrico M., Nye, Lauren, Obi, Andrea T., Okeson, Jeffrey P., Oliveira, Carlos R., Ong, Peck Y., Oram, Daniel S., Ortiz, David D., Ozgonenel, Bulent, Pacak, Karel, Padin-Rosado, Jose A., Padungkiatsagul, Tanyatuth, Paladine, Heather L., Pandolfino, John E., Patel, Deval, Patton, Simon, Penna, Gerson O., Penna, Maria Lucia, Perkins, Allen, Peterson, Leah, Petroianu, Georg A., Petronic-Rosic, Vesna M., Phan, Hanna, Pietroni, Mark, Plotnikoff, Gregory A., Pollart, Susan M., Poon, Jennifer, Porter, Andrew S.T., Powell, Charles, Pusateri, Margaret, Quinn, James M., Rahko, Peter S., Rajkumar, S. Vincent, Rajpara, Anand, Ramakrishnan, Kalyanakrishnan, Ramirez, Julio A., Rana, Jatin, Rank, Matthew A., Raoult, Didier, Rapose, Alwyn, Rau, Rachel E., Ravindran, Anita, Regehr, Jared, Reid, Ian R., Rennert-May, Elissa, Rew, Karl, Rezapour, Mona, Rhyne, Amanda, Riese, Martha, Robbins, David C., Robert, Sophie, Robertson, Amy D., Robinson, Malcolm, Roche, William P., Rohrberg, Tessa, Rose, Candice, Rose, Peter G., Ross, Stephen, Roth, Alan R., Ruha, Anne-Michelle, Rundell, Kristen, Said, Adnan, Sairenji, Tomoko, Samson, Susan L., Sanchez, Carlos E., Sangodkar, Sandeep, Santana, Arelis, Sarode, Ravindra, Schatz, Michael, Schevchuck, Alex, Schiller, Lawrence R., Schrager, Sarina, Schuller, Dan, Seashore, Justin, Seery, Amy, Seifert, Steven A., Semel, Jeffery D., Shaffi, Saeed Kamran, Shah, Beejal, Shah, Meera, Shah, Prediman Krishan, Shah, Shenil, Shammo, Jamile M., Shapiro, Eugene D., Sharara, Ala I., Sharma, Sonal, Sheehan, John P., Sherman, Kamille S., Shevy, Laura Elyse, Shew, Sable, Sierpina, Victor S., Sievers, Karlynn, Silk, Hugh, Simon, Lisa, Sinclair, Aaron D., Siraj, Dawd S., Smith, Jeannina, Smith, Zachary L., Soder, Rupal, Sojka, John, Somers, William J., Song, Mihae, Sosa, Nestor, Sowder, Timothy, Speer, Linda, St. Louis, Erik Kent, Stephens, Todd, Stiles, Melissa, Stratakis, Constantine, Stulberg, Daniel, Suárez, José D., Takashima, Masayoshi, Takyar, Varun, Talhari, Carolina, Tang, Jie, Tate, Jessica, Templeton, Kim, Teng, Joyce M.C., Thomson, Joanna, Tillett, William, Timbadia, Paresh J., Tobin, Kenneth, Tsaltas, Theodore T., Unizony, Sebastian H., Unruh, Mark, Uppendahl, Locke, Vallurupalli, Anusha, Van Buren, George, II, van Duin, David, Van Durme, Daniel J., Varlamov, Elena V., Veglia, Megan, Vélez, Christopher, Vercellotti, Gregory, Vincent, Kyle, Vinh, Donald C., Vyas, Jatin Mahesh, Wagner, Tamara, Wakefield, Thomas W., Wald, Arnold, Wald, Ellen R., Walker, Robin A., Wang, Ernest, Wang, Jennifer, Watanabe, Koji, Weber, Ruth, Wehler, Cheryl, Wei, Alice C., Weida, Jane A., Weissman, David N., Welliver, Robert C., Sr., Wester, Rebecca M., Wexler, Randell, Wilamowska, Katarzyna, Williams, Kimberly, Williams, Tracy L., Winterhoff, Boris, Wipperman, Jennifer, Wirtz, Mark W., Wittler, Robert, Wood, Gary S., Worswick, Scott, Wu, Dominic J., Wu, Steve W., Wyre, Hadley, Yakubov, Steven, Yang, Xinghong, Yang, Yul W., Yew, Kenneth S., Yi, Yooni, Yiannias, James A., Young, Natawadee, and Zea Vera, Alonso G.

Published
2023
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136. Prostate cancer

Author

Nelson, William G., De Marzo, Angelo M., and Isaacs, William B.

Subjects
Prostate cancer -- Risk factors, Prostate cancer -- Genetic aspects
Abstract

Genetics, lifestyle, and diet probably contribute to the development of prostate cancer in most men. Carcinogens in cooked meats may be a risk factor and vegetables may prevent prostate cancer. Research has also shown that infection or inflammation in the prostate may be a precursor of prostate cancer. Genes associated with prostate cancer include RNASEL, MSR1, AR, CYP17, SRD5A2, GSTP1, NKX3.1, PTEN, and CDKN1B.

Published
2003

138. List of Contributors

Author

Aisner, Dara L., primary, Barmada, M. Michael, additional, Bedard, Philippe L., additional, Beenhouwer, David O., additional, Behari, Jaideep, additional, Berdasco, Maria, additional, Bethel, Carlise R., additional, Biggs, Joseph R., additional, Bullock, Grant C., additional, Campbell, Sheldon M., additional, Chan, Wai-Yee, additional, Coleman, William B., additional, Cremona, Mattia, additional, De Marzo, Angelo M., additional, Dinh, Phuong, additional, Dolgachev, Vladislav, additional, Espina, Virginia, additional, Esteller, Manel, additional, Farver, Carol F., additional, Funkhouser, William K., additional, Gotlieb, Avrum I., additional, Hevner, Robert F., additional, Highsmith, W. Edward, additional, Keene, C. Dirk, additional, Kemmner, Wolfgang, additional, Key, Nigel S., additional, Lee, Hong Kee, additional, Lefferts, Joel A., additional, Lemasters, John J., additional, Lerch, Markus M., additional, Liotta, Lance A., additional, Luchini, Alessandra, additional, Liu, Amber Chang, additional, Lu, Karen, additional, Lukacs, Nicholas W., additional, Ma, Alice D., additional, Mayerle, Julia, additional, Mensink, Kara A., additional, Mok, Samuel Chi-ho, additional, Singh Monga, Satdarshan (Paul), additional, Montine, Thomas J., additional, Moore, Jason H., additional, Mottl, Amy K., additional, Munger, Karl, additional, Nagymanyoki, Zoltan, additional, Nelson, William G., additional, Nester, Carla, additional, Oethinger, Margret D., additional, Pang, Alan L.-Y., additional, Petricoin, Emanuel F., additional, Rivenbark, Ashley G., additional, Rhodes, C. Harker, additional, Rubinas, Tara C., additional, Schafer, Reinhold, additional, Sendler, Matthias, additional, Sepulveda, Antonia R., additional, Sers, Christine, additional, Silverman, Lawrence M., additional, Snoj, Natasa, additional, Sonnen, Joshua A., additional, Sotiriou, Christos, additional, Tsongalis, Gregory J., additional, Wessagowit, Vesarat, additional, Whitcomb, David C., additional, Wong, Kwong-kwok, additional, Zander, Dani S., additional, and Zhang, Dong-Er, additional

Published
2010
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140. Association of Serum Carotenoids and Retinoids with Intraprostatic Inflammation in Men without Prostate Cancer or Clinical Indication for Biopsy in the Placebo Arm of the Prostate Cancer Prevention Trial.

Author

Chadid, Susan, Song, Xiaoling, Schenk, Jeannette M., Gurel, Bora, Lucia, M. Scott, Thompson Jr., Ian M., Neuhouser, Marian L., Goodman, Phyllis J., Parnes, Howard L., Lippman, Scott M., Nelson, William G., De Marzo, Angelo M., and Platz, Elizabeth A.

Subjects
RETINOIDS, BIOPSY, HIGH performance liquid chromatography, BETA carotene, CONFIDENCE intervals, PROSTATITIS, CRYPTOXANTHIN, CAROTENOIDS, LYCOPENE, CAROTENES, VITAMIN A, LOGISTIC regression analysis, ODDS ratio, PROSTATE tumors
Abstract

Non-supplemental carotenoids and retinol may potentiate antioxidant and anti-inflammatory mechanisms. Chronic intraprostatic inflammation is linked to prostate carcinogenesis. We investigated the association of circulating carotenoids and retinol with intraprostatic inflammation in benign tissue. We included 235 men from the Prostate Cancer Prevention Trial placebo arm who had a negative end-of-study biopsy, most (92.8%) done without clinical indication. α-carotene, β-carotene, β-cryptoxanthin, lycopene, and retinol were assessed by high-performance liquid chromatography using pooled year 1 and 4 serum. Presence and extent of intraprostatic inflammation in benign tissue was assessed in 3 (of 6–10) biopsy cores. Logistic (any core with inflammation vs none) and polytomous logistic (some or all cores with inflammation vs none) regression was used to estimate odds ratios (OR) and 95% confidence intervals (CI) of intraprostatic inflammation by concentration tertile adjusting for age, race, prostate cancer family history, and serum cholesterol. None of the carotenoids or retinol was associated with intraprostatic inflammation, except β-cryptoxanthin, which appeared to be positively associated with any core with inflammation [vs none, T2: OR (95% CI) = 2.67 (1.19, 5.99); T3: 1.80 (0.84, 3.82), P-trend = 0.12]. These findings suggest that common circulating carotenoids and retinol are not useful dietary intervention targets for preventing prostate cancer via modulating intraprostatic inflammation. [ABSTRACT FROM AUTHOR]

Published
2022
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141. Cancer cells engineered to secrete granulocyte-macrophage colony-stimulating factor using ex vivo gene transfer as vaccines for the treatment of genitourinary malignancies

Author

Nelson, William G., Simons, Jonathan W., Mikhak, Bahar, Chang, Ju-Fay, DeMarzo, Angelo M., Carducci, Michael A., Kim, Michael, Weber, Christine E., Baccala, Angelo A., Goeman, Marti A., Clift, Shirley M., Ando, Dale G., Levitsky, Hyam I., Cohen, Lawrence K., Sanda, Martin G., Mulligan, Richard C., Partin, Alan W., Carter, H. Ballentine, Piantadosi, Steven, and Marshall, Fray F.

Published
2000
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142. List of Contributors

Author

Aisner, Dara L., primary, Barmada, M. Michael, additional, Bedard, Philippe, additional, Beenhouwer, David O., additional, Behari, Jaideep, additional, Berdasco, Maria, additional, Bethel, Carlise R., additional, Biggs, Joseph R., additional, Bullock, Grant C., additional, Campbell, Sheldon M., additional, Chan, Wai-Yee, additional, Coleman, William B., additional, De Marzo, Angelo M., additional, Dinh, Phuong, additional, Dolgachev, Vladislav, additional, Espina, Virginia, additional, Esteller, Manel, additional, Farver, Carol, additional, Fredolini, Claudia, additional, Funkhouser, William K., additional, Futschik, Matthias E., additional, Gotlieb, Avrum I., additional, Hevner, Robert, additional, Highsmith, W. Edward, additional, Keene, C. Dirk, additional, Kemmner, Wolfgang, additional, Key, Nigel S., additional, Lee, Hong Kee, additional, Lefferts, Joel A., additional, Lemasters, John J., additional, Lerch, Markus M., additional, Liotta, Lance, additional, Liu, Amber Chang, additional, Lu, Karen, additional, Lukacs, Nicholas W., additional, Ma, Alice, additional, Martin, Arlene, additional, Martin, Malcolm M., additional, Mayerle, Julia, additional, McGrath, John A., additional, Mensink, Kara A., additional, Mok, Samuel Chi-ho, additional, Monga, Satdarshan (Paul) Singh, additional, Montine, Thomas J., additional, Moore, Jason H., additional, Münger, Karl, additional, Nagymanyoki, Zoltan, additional, Nelson, William G., additional, Oethinger, Margret, additional, Pang, Alan LP, additional, Petricoin, Emanuel, additional, Rivenbark, Ashley, additional, Rhodes, C. Harker, additional, Rubinas, Tara, additional, Schafer, Reinhold, additional, Sendler, Matthias, additional, Sepúlveda, Antonia, additional, Sers, Christine, additional, Silverman, Lawrence M., additional, Snoj, Natasha, additional, Sonnen, Joshua A., additional, Sotiriou, Christos, additional, Tsongalis, Gregory J., additional, Wessagowit, Vesarat, additional, Whitcomb, David C., additional, Wong, Kwong-kwok, additional, Zander, Dani S., additional, Zhang, Dong-Er, additional, and Zhou, Weidong, additional

Published
2009
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145. Contributors

Author

Abbruzzese, James L., primary, Abeloff, Martin D., additional, Abou-Alfa, Ghassan K., additional, Abrahm, Janet L., additional, Abrams, Jeffery S., additional, Acs, Geza, additional, Aisner, Joseph, additional, Aisner, Seena C., additional, Alani, Rhoda M., additional, Alberts, Steven R., additional, Ambinder, Richard F., additional, Andritsos, Leslie A., additional, Appelbaum, Frederick R., additional, Apte, Sachin, additional, Armitage, James O., additional, Armstrong, Deborah, additional, Bagheri, Mamad M., additional, Balch, Charles M., additional, Balducci, Lodovico, additional, Beghé, Claudia, additional, Benjamin, Robert, additional, Bennett, Charles L., additional, Berkowitz, Ross Stuart, additional, Bernstein, Donna, additional, Bishop, Michael R., additional, Blot, William J., additional, Blumgart, Leslie, additional, Bommer, Guido T., additional, Borowitz, Michael J., additional, Brahmer, Julie R., additional, Bramwell, Viven H.C., additional, Brock, Malcom V., additional, Bydon, Ali, additional, Cairo, Mitchell S., additional, Campana, Dario, additional, Carbone, David P., additional, Carter, H. Ballentine, additional, Chadha, Manpreet K., additional, Chan, Daniel W., additional, Chang, Alfred E., additional, Cheung, Nai-Kong V., additional, Christian, Michaele, additional, Clarke, Michael F., additional, Cmelak, Anthony, additional, Coccia, Peter F., additional, Cohen, Alfred M., additional, Coleman, Robert E., additional, Compton, Carolyn, additional, Cooley, Linda D., additional, Cortes, Jorge, additional, Courtneidge, Sara A., additional, Cowan, Kenneth H., additional, Culkin, Daniel J., additional, Dalmau, Josep, additional, D'Angio, Giulio J., additional, Dawson, Laura, additional, Deitcher, Steven R., additional, DeMatteo, Ronald P., additional, DeSimone, Philip A., additional, DeWeese, Theodore L., additional, Digumarthy, Subba R., additional, Dispenzieri, Angela, additional, Dome, Jeffrey S., additional, Donohue, John H., additional, Doroshow, James H., additional, Drebin, Jeffery A., additional, Duda, Dan G., additional, Duffy, Austin, additional, Duska, Linda R., additional, Eisenberger, Mario A., additional, Elstrom, Rebecca L., additional, Erler, Janine T., additional, Ewer, Michael S., additional, Fearon, Eric R., additional, Fecher, Leslie A., additional, Fichera, Alessandro, additional, Filipovich, Alexandra H., additional, Fitzner, Karen A., additional, Foote, Robert L., additional, Foran, James M., additional, Forastiere, Arlene A., additional, Ford, James M., additional, Freifeld, Alison G., additional, Freter, Carl E., additional, Fuller, Arlan F., additional, Furth, Emma E., additional, Garofalo, Michael C., additional, Gebhardt, Mark C., additional, Gerber, N. Lynn, additional, Gharia, Manish, additional, Giaccia, Amato J., additional, Gilbert, Mark R., additional, Glaspy, John, additional, Glover, Katrina Y., additional, Gokaslan, Ziya L., additional, Gökbuget, Nicola, additional, Goldstein, Donald Peter, additional, Gonzalez, Adriana, additional, Goodman, Anne Kathryn, additional, Gordon, Ellen, additional, Green, Daniel M., additional, Grever, Michael R., additional, Grigg, Andrew, additional, Grochow, Louise, additional, Gross, Thomas G., additional, Grossman, Stuart A., additional, Gunderson, Leonard L., additional, Gunkel, Juliet, additional, Gutierrez, Martin, additional, Habermann, Thomas M., additional, Haik, Barrett G., additional, Hainsworth, John D., additional, Hallahan, Dennis, additional, Hanna, Nader N., additional, Harris, Eleanor E.R., additional, Hawk, Ernie, additional, Heideman, Nancy H., additional, Heideman, Richard L., additional, Helman, Lee J., additional, Hochberg, Jessica, additional, Hoelzer, Dieter, additional, Holen, Ingunn, additional, Horning, Sandra J., additional, Huang, Kim, additional, Illei, Peter B., additional, Jaffe, Elaine S., additional, Jagannath, Sanjay B., additional, Jain, Rakesh K., additional, Jarnagin, William, additional, Jhingran, Anuja, additional, Johnson, David H., additional, Jones, Heather, additional, Judy, Kevin D., additional, Juergens, Rosalyn A., additional, Kant, Jeffrey A., additional, Kantarjian, Hagop, additional, Karcioglu, Zeynel A., additional, Karyadi, Danielle M., additional, Kased, Norbert, additional, Kastan, Michael B., additional, Kaul, Daniel R., additional, Kawaoka, John, additional, Kemeny, Margaret, additional, Kemeny, Nancy, additional, Kensler, Thomas W., additional, Kleinberg, Lawrence R., additional, Kobrinsky, Boris, additional, Kowalski, Jeanne, additional, Kummar, Shivaani, additional, Lal, Geeta, additional, Lambert, Paul F., additional, Lange, Julie R., additional, Laskin, Janessa, additional, Lee, Fred, additional, Lee, Susanna I., additional, Lees, Jacqueline, additional, Lenzi, Renato, additional, Lerman, Caryn, additional, Lipton, Allan, additional, Loprinzi, Charles L., additional, Lozanski, Gerard, additional, Lustig, Robert, additional, Machtay, Mitchell, additional, Maity, Amit, additional, Malik, Uzma, additional, Manatt, C. Scott, additional, Mansour, John C., additional, Massion, Pierre P., additional, Mayer, R. Samuel, additional, McCormick, Beryl, additional, McDonald, Charles J., additional, McDougall, Ross, additional, McKenna, W. Gillies, additional, Meranze, Steven, additional, Metz, James M., additional, Meyskens, Frank L., additional, Michelassi, Fabrizio, additional, Mikkilineni, Radha, additional, Mock, Victoria, additional, Mohiuddin, Mohammed, additional, Montie, James, additional, Morton, A. Ross, additional, Murgo, Anthony J., additional, Neff, James R., additional, Nelson, William G., additional, Nesbit, Suzanne, additional, Niederhuber, John E., additional, O'Connor, Tracey, additional, O'Dorisio, Thomas, additional, Offit, Kenneth, additional, Onciu, Mihaela, additional, O'Reilly, Eileen M., additional, Ostrander, Elaine A., additional, O'Sullivan, Brian, additional, Pardoll, Drew M., additional, Park, Catherine K., additional, Patterson, Freda, additional, Pavletic, Steven Z., additional, Perry, Michael C., additional, Peterson, LoAnn C., additional, Phillips, Peter C., additional, Piantadosi, Steven, additional, Pili, Robert, additional, Pisters, Peter W.T., additional, Pittelkow, Mark R., additional, Plastaras, John P., additional, Platz, Elizabeth A., additional, Pribaz, Julian, additional, Pruitt, Amy A., additional, Pui, Ching-Hon, additional, Putnam, Joe Bill, additional, Quon, Harry, additional, Raber, Martin N., additional, Rajkumar, S. Vincent, additional, Regine, William F., additional, Ritter, Mark, additional, Roberts, John Robert, additional, Robinson-Bostom, Leslie, additional, Rodriguez, Ronald, additional, Rodriguez-Galindo, Carlos, additional, Rosenfeld, Myrna, additional, Rosenthal, Nadia, additional, Rubenstein, James L., additional, Rubin, Brian P., additional, Rupani, Reena, additional, Rusch, Valerie W., additional, Russell, Anthony H., additional, Ryan, Charles J., additional, Sacchini, Vergilio, additional, Sandler, Alan B., additional, Sandler, Howard, additional, Sandlund, John T., additional, Santana, Victor M., additional, Schnoll, Robert A., additional, Sciubba, Daniel M., additional, Seiden, Michael V., additional, Sekeres, Mikkael A., additional, Sharfman, William H., additional, Sharma, Ricky A., additional, Sideras, Kostandinos, additional, Silver, Kenneth, additional, Small, Eric J., additional, Smith, David C., additional, Sneed, Penny K., additional, Snow, Stephen N., additional, Sokoll, Lori J., additional, Sovak, Mika A., additional, Speyer, James L., additional, Spira, Alex I., additional, Springfield, Dempsey, additional, Spunt, Sheri L., additional, Stewart, Daniel, additional, Strickland, Paul T., additional, Sugden, Bill, additional, Sutcliffe, Siobhan, additional, Sun, Weijing, additional, Tallman, Martin S., additional, Talmadge, James E., additional, Tefferi, Ayalew, additional, Thom, Peter, additional, Thompson, Craig B., additional, Tisdale, Michael J., additional, Tobinai, Kensei, additional, Tomaszewski, Joseph E., additional, Topalian, Suzanne L., additional, Torti, Frank M., additional, Trump, Donald L., additional, Vallis, Katherine A., additional, Varadhachary, Gauri R., additional, Vemulapalli, Sreenivas, additional, Visvanathan, Kala, additional, Wagner-Johnston, Nina D., additional, Wahl, Richard L., additional, Watanabe, Toshiki, additional, Weber, Barbara L., additional, Weber, Sharon, additional, Weigel, Ronald J., additional, Weissman, Irving L., additional, Westra, William, additional, Wilson, Kathleen S., additional, Wilson, Wyndham H., additional, Wolff, Antonio C., additional, Wong, Sandra L., additional, Wood, Gary S., additional, Wyatt, Lance S., additional, Zakarija, Anaadriana, additional, Zaks, Tal Z., additional, and Zell, Jason A., additional

Published
2008
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146. Prostate Cancer

Author

Nelson, William G., primary, Carter, H. Ballentine, additional, DeWeese, Theodore L., additional, and Eisenberger, Mario A., additional

Published
2008
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149. GSTP1 positive prostatic adenocarcinomas are more common in Black than White men in the United States

Author

Vidal, Igor, primary, Zheng, Qizhi, additional, Hicks, Jessica L., additional, Chen, Jiayu, additional, Platz, Elizabeth A., additional, Trock, Bruce J., additional, Kulac, Ibrahim, additional, Baena-Del Valle, Javier, additional, Sfanos, Karen S., additional, Ernst, Sarah, additional, Jones, Tracy, additional, Glavaris, Stephanie, additional, Nelson, William G., additional, Yegnasubramanian, Srinivasan, additional, and De Marzo, Angelo M., additional

Published
2020
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