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Researchers from McGill University in Montreal, Canada, conducted a study focusing on optimizing IOL calculators using deep learning prediction of total corneal astigmatism (TCA). The study aimed to identify the most accurate regression model for predicting TCA from anterior corneal astigmatism (ACA) and fine-tune the model's architecture for better accuracy. The deep learning approach outperformed traditional methods, leading to more precise TCA calculations and potentially enhancing surgical outcomes. The research was published in the Journal of Clinical Medicine and can be accessed for further information. [Extracted from the article]

A recent study from McGill University in Montreal, Canada, explores the roles of the DCAP-2 decapping scaffolds EDC-3 and EDC-4 in embryonic development in C. elegans. EDC-3 is found to facilitate the timely removal of specific embryonic mRNAs and define boundaries between different cellular structures, while EDC-4 counteracts EDC-3 and plays a role in the assembly of DCAP-2 with the GID complex. The research suggests that multiple RNA decay mechanisms are involved in clearing maternal and zygotic mRNAs throughout embryonic development. [Extracted from the article]

A recent study conducted at Concordia University in Montreal, Canada, explored the relationship between second language anxiety in conversation and speakers' perceptions of the interaction and their social networks. The research involved measuring the galvanic skin response of 60 L2 English speakers during conversation and analyzing their self-perceptions, partner perceptions, trait-anxiety, and social network characteristics. The findings indicated that high arousal during interaction was associated with negative self-perceptions of speech fluency and negative perceptions of their partner's engagement. This research sheds light on the impact of state-anxiety triggered by partner- or task-specific experiences in language communication. [Extracted from the article]

A recent report from McGill University discusses the importance of integrating sex and gender considerations in cross-cultural traumatic stress studies. The research highlights challenges in defining sex and gender from a Western perspective while acknowledging cultural differences, as well as legal and ethical obstacles faced by non-Western and low-to-middle income regions. Recommendations include participatory approaches involving community members, risk analyses, sensitive research methods, and clear reporting to ensure diverse experiences are respected and safeguarded in research. The study emphasizes the need for ethical and meaningful research that incorporates sex and gender considerations in cross-cultural studies of traumatic stress. [Extracted from the article]

Researchers at the University of Montreal have explored the concept of desexualization in Freud's thinking after 1920, as discussed in the article "Desexualization: an Interesting Problem In the Ego and the Id." The study highlights Freud's use of a 'desexualized libido' to address the dichotomy between life and death drives, leading to a split in the ego itself. This research, published in the International Journal of Psychoanalysis, offers insights into the complexities of psychoanalysis and Freud's evolving theories. [Extracted from the article]

A recent study conducted at Universite du Quebec a Montreal in Canada explored how gaze communicates both cue direction and agent mental states. The research found that performance was compromised when cue direction and mental content were dissociated, especially when a social avatar was used as a cue. The study concluded that a typical gaze signal conveys information about both an agent's attention and what they are attending to. This study was published in Frontiers in Psychology and can be accessed online for further information. [Extracted from the article]

A research report from the University of Montreal delves into the comparison between Freud and Klein's views on repression, guilt, and the super-ego in psychoanalysis. Klein's emphasis on moderating the severity of the super-ego to create a more humane inner world is highlighted, along with the idea of standing up to terrifying unconscious objects rather than trying to eliminate them. The research, titled "A Kleinian Appreciation of the Ego and the Id (1923-2023)," was published in the International Journal of Psychoanalysis and emphasizes the importance of understanding and challenging the inner workings of the mind. [Extracted from the article]

Researchers at McGill University conducted a study on single mothers in a Kenyan slum to understand the factors contributing to their stress levels. The research found that despite receiving support from kin, single mothers faced elevated stress due to limited support from the child's father, particularly in terms of financial assistance. The study highlights the importance of social support for single mothers in precarious urban environments for their psychological well-being. This research was supported by various organizations and has been peer-reviewed, providing valuable insights into the challenges faced by single mothers in low-income settings. [Extracted from the article]

A recent study conducted by Concordia University in Montreal, Canada, focused on pediatric glioblastomas and their complex dynamics. The research utilized single-cell trajectory inference algorithms to identify key genes and signals regulating glioblastoma-immune network dynamics, potentially leading to new targeted therapies. The findings suggest the importance of integrating quantitative approaches and artificial intelligence to better understand pediatric glioblastoma tumor-immune interactions, offering insights into potential treatment strategies. This research has been peer-reviewed and provides valuable information for those interested in oncology, genetics, and pediatric health. [Extracted from the article]

A recent study from McGill University explores the relationship between externalizing and internalizing symptoms in childhood and adolescence and their impact on adolescent gambling behaviors. The research suggests that stable high externalizing behaviors in development may increase the risk of engaging in gambling activities during adolescence. Efforts to target these behaviors throughout development could potentially reduce the likelihood of future gambling behaviors. This peer-reviewed study provides valuable insights into the complex interplay between mental health trajectories and adolescent gambling participation. [Extracted from the article]

A recent report from McGill University in Montreal, Canada, discusses Dante Cicchetti's organizational-developmental perspective on Down Syndrome and its contributions to developmental psychopathology. The research highlights the importance of developmental level, organization of development, genetic conditions, narratives about ways of being, and the influence of the environment on individuals with neurodevelopmental conditions. This study, supported by the Social Sciences and Humanities Research Council of Canada, provides insights for future research with populations such as those with Down syndrome, genetic syndromes associated with intellectual disability, and autism. [Extracted from the article]

Researchers at McGill University conducted a study on brain health as a unified construct in individuals aging with HIV. Using network analysis, they found that brain health involves cognitive, emotional, and motor domains, with key symptoms related to enjoyment of life and negative feelings. The study, which included 710 men from five Canadian cities, concluded that future research should replicate these findings in larger and more diverse samples for confirmation. The research was published in Social Psychiatry and Psychiatric Epidemiology and can be accessed online. [Extracted from the article]

A study conducted at McGill University Health Center in Montreal, Canada, focused on the safety and effectiveness of medical cannabis in real-world clinical practice. Over a 4-year period, 2991 adult patients were enrolled and followed for up to 12 months after initiating medical cannabis treatment. The study found statistically significant improvements in pain severity, interference, relief, symptoms, and quality of life dimensions within 3 months of treatment initiation, with clinically significant improvements in pain interference, tiredness, anxiety, and well-being from baseline. The research concluded that medical cannabis directed by physicians appears to be safe and effective for a variety of medical indications within a short timeframe. [Extracted from the article]

A study conducted at McGill University in Montreal, Canada, focused on the acceptability of a Serious Illness Conversation Guide (SICG) among African Americans with advanced cancer and their clinicians. The research found that the adapted SICG was well-received by Black patients with advanced cancer, promoting meaningful conversations and connection. Oncologists also found the conversations feasible and skill-building, suggesting that the SICG could be a valuable tool in addressing disparities in advanced cancer care among marginalized populations. The study was supported by the Richard A. Cantor Fund for Communications Research in Palliative Care and has been peer-reviewed. [Extracted from the article]

Researchers from the Montreal Clinical Research Institute conducted a study on the impact of acute soluble fiber supplementation on post-prandial glucose levels in adults with cystic fibrosis and glucose intolerance. The study found that fiber supplementation did not have a beneficial effect on blood glucose control in patients with cystic fibrosis-related diabetes or impaired glucose tolerance. This research was funded by the Canadian Cystic Fibrosis Foundation and J-A DeSeve search chair in clinical research, and the findings were published in the journal Annales d Endocrinologie. [Extracted from the article]

A recent study from McGill University in Montreal, Canada, focused on altered biventricular function in neonatal hypoxic-ischaemic encephalopathy. The research compared cardiac function in newborns with this condition to controls using echocardiography, finding higher estimated systolic pulmonary pressure and altered right and left ventricular function in the hypoxic-ischaemic encephalopathy group. The study concluded that newborns with this condition exhibit signs of increased pulmonary pressures and altered biventricular systolic and diastolic function. For more information, the study can be found in Cardiology in the Young, 2023;33(9):1587-1596. [Extracted from the article]

A recent study conducted by Concordia University examined social interaction profiles among youth with intellectual disabilities (ID) and their impact on self-esteem, aggressive behaviors, and prosocial behaviors. The research identified four profiles: Socially Isolated, Socially Integrated, Socially Rejected, and Socially Connected, with the socially integrated and connected profiles showing higher self-esteem, more prosocial behaviors, and less aggressive behaviors compared to the isolated and rejected profiles. Funded by the Australian Research Council and the Social Sciences and Humanities Research Council of Canada, this peer-reviewed study provides valuable insights into the psychosocial adjustment of youth with ID. For more information, the Journal of Autism and Developmental Disorders can be contacted. [Extracted from the article]

A recent report from McGill University discusses the resurgence of psychedelic drug research for mental disorders in Western society. The study highlights the intricate mechanisms of action of psychedelics, focusing on psilocybin and LSD, and their impact on brain circuits and cognitive experiences. The research suggests that psychedelics may offer a novel conceptual framework in psychiatry for treating mental health disorders and integrating brain, mind, and spirituality. This peer-reviewed study provides valuable insights into the potential therapeutic benefits of psychedelics. [Extracted from the article]

A recent study conducted at HEC Montreal explores the relationship between team psychological capital and adaptivity in new product development teams. The research, supported by FRQSC and SSHRC, found that team creativity mediates the positive association between team PsyCap and adaptivity, with the level of outcome focus moderating this relationship. This peer-reviewed study sheds light on the factors that enhance adaptability in project management teams, offering valuable insights for future research in the field of Psychology and Psychiatry. [Extracted from the article]

Researchers at McGill University Health Center in Montreal, Canada, have discovered a form of synaptic heterogeneity in the mouse cerebellum that affects Purkinje cell timing. This heterogeneity in slow synaptic transmission varies across different regions of the cerebellum, resulting in diverse functional outputs. The study found that the properties of slow synaptic transmission can vary by up to threefold, impacting the firing patterns of Purkinje cells based on their location. This research sheds light on the complex molecular and cellular mechanisms underlying brain function and has been published in the Journal of Neuroscience. [Extracted from the article]

Researchers from the Montreal Heart Institute conducted a study on the association of genetically predicted skipping of col4a4 exon 27 with hematuria and albuminuria. The study utilized genetic data from the UK Biobank and gene expression data from kidney cortex samples to identify potential biological mechanisms influencing hematuria. The research identified significant associations between gene expression and splicing events, specifically linking the skipping of COL4A4 exon 27 to hematuria and albuminuria. This study was funded by various organizations and has been peer-reviewed for publication in the Journal of the American Society of Nephrology. [Extracted from the article]

A recent study conducted at the Montreal Clinical Research Institute (IRCM) in Canada has shed light on the role of protein UFMylation in the early events of ribosomal DNA-damage response in Ataxia Telangiectasia. The research highlights the importance of UFMylation in orchestrating DNA double-strand break repair in human cells, particularly in regulating ATM activation and rDNA transcriptional silencing. This study provides valuable insights into the mechanisms underlying the response to genotoxic stress in neurodegenerative diseases like Ataxia Telangiectasia. [Extracted from the article]

Researchers at the National Research Council of Canada have synthesized sulfated lactosyl glycosides (SLGs) to evaluate their potential as vaccine adjuvants. These SLGs were compared to SLA archaeosomes in an in vivo murine vaccine model to assess their effectiveness. The study aims to understand the mechanism behind the strong immunogenic properties of SLA archaeosomes and explore structural changes for enhanced vaccine adjuvanticity. The research, funded by CGIAR and the Federal Research and Development Organization of the Government of Canada, has been peer-reviewed and published in the New Journal of Chemistry. [Extracted from the article]

A recent study from McGill University in Montreal, Canada, explores the role of Fibroblast Growth Factor 6 (FGF6) in various biological processes. FGF6 is a member of the Fibroblast Growth Factor family and is involved in cell proliferation, differentiation, and migration. It also plays a role in myogenesis, muscular regeneration, angiogenesis, iron transport, and lipid metabolism. Additionally, FGF6 has been implicated in the development of certain cancers. The research has been peer-reviewed and provides valuable insights into the functions and implications of FGF6. [Extracted from the article]

A recent study conducted by McGill University in Montreal, Canada, examined the incidence and risk factors associated with first detections and redetections of human papillomavirus (HPV) infections in adult women. The study followed women aged 18-60 years from Sao Paulo, Brazil, for up to 10 years. The findings suggest that many HPV redetections are likely reactivations of latent recurring infections, and the incidence of redetection with the same HPV genotype is higher than the incidence of first detection. Redetections were not associated with new sexual partners. This research provides valuable insights into the nature of HPV infections in women. [Extracted from the article]

A recent study conducted by the University of Montreal aimed to evaluate the effectiveness of a program called Pastel in reducing test anxiety among adolescents. The program, which combines cognitive-behavioral therapy and study skills, was tested on 48 adolescents aged 14 to 17 years. The results showed a medium effect on test anxiety immediately after the program and a low effect after six months. The program also appeared to have positive impacts on secondary outcomes such as social anxiety and depressive symptoms. This study contributes to the existing literature on test anxiety in adolescents and offers a promising intervention for reducing related symptoms. [Extracted from the article]

A report from McGill University in Montreal, Canada discusses the role of social environments in shaping mental disorders. The research emphasizes a cultural-ecosocial approach that considers how cultural meaning and practices mediate the effects of social determinants on mental health. It highlights the importance of understanding the ways in which social systems influence the causes, expression, course, and outcome of mental disorders. The report concludes that 'the social' refers to interactional processes that create material and symbolic structures that provide both challenges and resources for healing and adaptation. This research has been peer-reviewed and is published in the journal Social Psychiatry and Psychiatric Epidemiology. [Extracted from the article]

A recent study conducted at McGill University in Montreal, Canada explored the relationship between negative urgency (the tendency to act impulsively when experiencing negative emotions) and reward processing in women with and without binge eating. The study involved 153 women who completed experimental tasks under both stressful and relaxed conditions, assessing their physiological, behavioral, and self-report indices of reward processing of palatable food. Contrary to expectations, the study found that reward processing of food was not heightened when participants were stressed compared to when they were relaxed. The findings are discussed in relation to previous research on negative urgency. [Extracted from the article]

A recent study conducted by McGill University in Montreal, Canada, explores the potential for telemedicine in pediatric emergency care. The researchers aimed to assess the suitability of telemedicine for virtual visits in this setting. They analyzed data from a Canadian pediatric hospital and found that 37.9% of in-person visits to the pediatric emergency department could potentially be conducted virtually. Factors such as overnight visits, non-Canadian citizenship, ethnocultural vulnerability, and consultations for head trauma were associated with higher telemedicine suitability. The study emphasizes the importance of considering local patient and visit-level characteristics when designing telemedicine models for pediatric acute care. [Extracted from the article]

A recent study conducted by McGill University in Montreal, Canada, explores the relationship between different types of stressors experienced throughout a person's life and the severity of major depressive disorder (MDD). The study analyzed data from a community-based cohort and found that proximal stressors were associated with melancholic depression, while severe atypical depression and moderate depression were linked to specific domains of stressful life events. Additionally, individuals with severe atypical depression and melancholic depression were more likely to have experienced childhood maltreatment. The findings suggest the need for tailored interventions and clinical management based on the unique stressor profiles and MDD subtypes of patients. [Extracted from the article]

A recent study conducted by researchers at Polytechnique Montreal explores the use of an internal DO plate fixator (IDOPF) as an alternative to external fixators and intramedullary nails for distraction osteogenesis (DO) in pediatric patients. The researchers created a finite element model to test the IDOPF's ability to withstand partial weight bearing and create a favorable mechanical environment for bone regeneration. The results showed that the IDOPF was able to provide stability and support bone healing, although high contact stresses at the telescopic interfaces may cause wear. This study is a step towards refining the IDOPF design for clinical use. [Extracted from the article]

A scoping review conducted by researchers at the University of Montreal examined the effects of recreational cannabis legalization (RCL) on mental health. The review found a lack of research and inconclusive results regarding the impact of RCL on mental health. The studies included in the review focused on various populations and diagnoses, but there were gaps in the examination of cannabis use patterns among people receiving psychiatric care and the availability of longitudinal studies. The researchers concluded that collaboration between clinicians, researchers, and policymakers is necessary to address these research gaps and develop evidence-based policies. [Extracted from the article]

A study conducted by researchers at Concordia University in Montreal, Canada, focused on the relationship between bilingualism and Alzheimer's disease (AD). The study examined brain and cognitive reserve in older adults with or at risk for AD and found that bilingualism may contribute to brain maintenance in the context of AD. The researchers used surface-based morphometry methods to measure cortical thickness and volume of language-related and AD-related brain regions. The study concluded that while no evidence of brain reserve was observed in language-related regions, reduced hippocampal volume was observed in monolingual older adults with AD. The research was supported by the Natural Sciences and Engineering Research Council of Canada (NSERC) and the Canadian Institutes of Health Research (CIHR). [Extracted from the article]

A recent study conducted by the University of Montreal explores the relationship between psychopathic traits in childhood, peer victimization, and depression symptoms in adolescence. The study, which used data from the Quebec Longitudinal Study of Child Development, found that youth with psychopathic traits are more likely to engage in physical aggression and experience victimization from peers, which is associated with symptoms of depression. The study also suggests that the association between psychopathic traits and depression symptoms is mediated by peer victimization, particularly for children with low levels of physical aggression. These findings highlight the importance of considering the role of peer victimization and physical aggression when examining the link between psychopathic traits and subsequent depression symptoms. [Extracted from the article]

A report from McGill University discusses research on anxiety disorders and their impact on online video interactions. The study examined how individuals perceive themselves and others in these interactions, and whether social anxiety affects these perceptions. The findings showed that people generally believed others viewed them positively and understood others' impressions of them in both online and in-person interactions. However, social anxiety was found to impair individuals' positive self-perception and their liking of others in both contexts. The study suggests that these findings have important implications for individuals with higher social anxiety. [Extracted from the article]

A recent study conducted by researchers at McGill University Health Center in Montreal, Canada, examined the association between very-low density lipoprotein cholesterol (VLDL-C) and apolipoprotein B (ApoB) with the risk of new onset cardiovascular events. The study analyzed data from the UK Biobank and Framingham Heart Study cohorts and found that both VLDL-C and ApoB were significantly associated with atherosclerotic cardiovascular disease. However, when adjusted for high-density lipoprotein cholesterol (HDL-C), the association of VLDL-C with cardiovascular risk was no longer clinically meaningful. The researchers concluded that adjustment for HDL-C cannot be ignored in assessing cardiovascular risk. [Extracted from the article]

Researchers at Concordia University in Montreal, Canada have developed a new method for controlling the interaction force of a cardiac ultrasound robotic system (CURS) using artificial intelligence (AI) and dual control loops. The system adjusts the force based on ultrasound image feedback, allowing it to adapt to different cardiac views and improve image quality and patient safety during examinations. The researchers found that their approach, which incorporates an adaptive filtered quasi-sliding mode controller (AFQSMC), outperformed traditional constant force control methods in experimental evaluations. This study was supported by the Natural Sciences and Engineering Research Council of Canada (NSERC) and FRQNT Doctoral Scholarship. [Extracted from the article]

A recent study conducted by the University of Montreal examined the effects of recreational cannabis legalization (RCL) on mental health. The researchers conducted a scoping review of 28 studies from the United States and Canada, which revealed a lack of research and inconclusive results. The study highlighted the need for collaboration between clinicians, researchers, and policymakers to address research gaps and develop evidence-based policies regarding RCL. The findings emphasize the importance of understanding the effects associated with RCL in order to make informed decisions. [Extracted from the article]