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101. Prevention of Premature Discontinuation of Dual Antiplatelet Therapy in Patients With Coronary Artery Stents: A Science Advisory From the American Heart Association, American College of Cardiology, Society for Cardiovascular Angiography and Interventions, American College of Surgeons, and American Dental Association, With Representation From the American College of Physicians

Author

Grines, Cindy L., Bonow, Robert O., Casey, Donald E., Jr, Gardner, Timothy J., Lockhart, Peter B., Moliterno, David J., O'Gara, Patrick, and Whitlow, Patrick

Published
2007
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104. Identification, Diagnosis and Treatment of Heparin-induced Thrombocytopenia and Thrombosis: A Registry of Prolonged Heparin Use and Thrombocytopenia among Hospitalized Patients with and without Cardiovascular Disease: The Complication After Thrombocytopenia Caused by Heparin (CATCH) Registry Steering Committee

Author

Ohman, E. Magnus, Granger, Christopher B., Rice, Lawrence, Abrams, Charles S., Becker, Richard C., Berger, Peter B., Kleiman, Neal S., Moliterno, David, Moll, Stephan, Rodgers, Jo E., Steinhubl, Stephen S., Tapson, Victor F., Sinnaeve, Peter, and Anstrom, Kevin J.

Published
2005
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109. Heparin-induced thrombocytopenia and cardiovascular diseases

Author

Das, Pranab, Ziada, Khaled, Steinhubl, Steven R., Moliterno, David J., Hamdalla, Hussam, Jozic, Joseph, and Mukherjee, Debabrata

Subjects
Cardiovascular diseases, Health
Abstract

To link to full-text access for this article, visit this link: http://dx.doi.org/10.1016/j.ahj.2005.10.005 Byline: Pranab Das, Khaled Ziada, Steven R. Steinhubl, David J. Moliterno, Hussam Hamdalla, Joseph Jozic, Debabrata Mukherjee Author Affiliation: Division of Cardiovascular Medicine, Gill Heart Institute, University of Kentucky, Lexington, KY Article History: Received 25 June 2005; Accepted 13 October 2005

Published
2006

110. Vorapaxar with or without clopidogrel after non–ST-segment elevation acute coronary syndromes: Results from the Thrombin Receptor Antagonist for Clinical Event Reduction in Acute Coronary Syndrome trial

Author

Tricoci, Pierluigi, Lokhnygina, Yuliya, Huang, Zhen, Van de Werf, Frans, Cornel, Jan H., Chen, Edmond, Wallentin, Lars, Held, Claes, Aylward, Philip E., Moliterno, David J., Jennings, Lisa K., White, Harvey D., Armstrong, Paul W., Harrington, Robert A., Strony, John, and Mahaffey, Kenneth W.

Published
2014
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111. Healing achilles-sirolimus versus paclitaxel

Author

Moliterno, David J.

Subjects
Paclitaxel -- Testing, Clinical trials
Abstract

The findings from randomized, head-to-head comparisons of a sirolimus-eluting stent with a paclitaxel-eluting stent are presented. The data overall from randomized clinical trials and from registries suggests that the currently available sirolimus-eluting stents provide an angiographic and clinical edge over the currently available paclitaxel-eleuting stents.

Published
2005

114. Ticagrelor alone vs. ticagrelor plus aspirin following percutaneous coronary intervention in patients with non-ST-segment elevation acute coronary syndromes: TWILIGHT-ACS

Author

Baber, Usman, primary, Dangas, George, additional, Angiolillo, Dominick Joseph, additional, Cohen, David Joel, additional, Sharma, Samin Kumar, additional, Nicolas, Johny, additional, Briguori, Carlo, additional, Cha, Jin Yu, additional, Collier, Timothy, additional, Dudek, Dariusz, additional, Džavik, Vladimir, additional, Escaned, Javier, additional, Gil, Robert, additional, Gurbel, Paul, additional, Hamm, Christian W, additional, Henry, Timothy, additional, Huber, Kurt, additional, Kastrati, Adnan, additional, Kaul, Upendra, additional, Kornowski, Ran, additional, Krucoff, Mitchell, additional, Kunadian, Vijay, additional, Marx, Steven Owen, additional, Mehta, Shamir, additional, Moliterno, David, additional, Ohman, Erik Magnus, additional, Oldroyd, Keith, additional, Sardella, Gennaro, additional, Sartori, Samantha, additional, Shlofmitz, Richard, additional, Steg, Philippe Gabriel, additional, Weisz, Giora, additional, Witzenbichler, Bernhard, additional, Han, Ya-Ling, additional, Pocock, Stuart, additional, Gibson, Charles Michael, additional, and Mehran, Roxana, additional

Published
2020
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115. TCT CONNECT-64 Impact of DAPT Cessation in High Bleeding-Risk Patients Undergoing PCI: Insights From the PARIS Registry

Author

Cao, Davide, primary, Dangas, George, additional, Sartori, Samantha, additional, Zhang, Zhongjie, additional, Ariti, Cono, additional, Chiarito, Mauro, additional, Nicolas, Johny, additional, Chandiramani, Rishi, additional, Goel, Ridhima, additional, Roumeliotis, Anastasios, additional, Nardin, Matteo, additional, Claessen, Bimmer, additional, Cohen, David, additional, Henry, Timothy, additional, Gibson, C. Michael, additional, Krucoff, Mitchell, additional, Moliterno, David, additional, Colombo, Antonio, additional, Weisz, Giora, additional, Witzenbichler, Bernhard, additional, Kini, Annapoorna, additional, Steg, Philippe, additional, Pocock, Stuart, additional, and Mehran, Roxana, additional

Published
2020
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118. Securing the Future for a Major Academic Cardiovascular Program: Hardwiring a Referral Network and Preparing for a Transition to Value-Based Reimbursement

Author

Smyth, Susan S., primary, Moliterno, David, additional, McClure, Rick, additional, Campbell, Justin, additional, Buckler, Lacey, additional, McMullen, Colleen A., additional, Whayne, Thomas F., additional, Endean, Eric, additional, Sekela, Michael, additional, and Karpf, Michael, additional

Published
2020
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122. Relationship of blood transfusion and clinical outcomes in patients with acute coronary syndromes

Author

Rao, Sunil V., Harrington, Robert A., Newby, L. Kristin, Moliterno, David J., Topol, Eric J., Armstrong, Paul W., Granger, Christopher B., Pieper, Karen, Lindblad, Lauren, Califf, Robert M., and Stamler, Jonathan S.

Subjects
Coronary heart disease -- Research, Blood transfusion -- Patient outcomes, Blood transfusion -- Research
Abstract

The association between blood transfusion and mortality among patients with acute coronary syndromes who develop bleeding, anemia or both during their hospital course are determined. It was found that blood transfusion in the setting of acute coronary syndromes is associated with higher mortality and this relationship persists after adjustment for other predictive factors and timing of events.

Published
2004

123. Association of diabetes mellitus and glycemic control strategies with clinical outcomes after acute coronary syndromes

Author

McGuire, Darren K., Newby, L. Kristin, Bhapkar, Manjushri V., Moliterno, David J., Hochman, Judith S., Klein, Werner W., Weaver, W. Douglas, Pfisterer, Matthias, Corbalan, Ramon, Dellborg, Mikael, Granger, Chrisotpher B., Van De Werf, Frans, Topol, Eric J., and Califf, Robert M.

Subjects
Diabetics -- Health aspects, Diabetics -- Research, Coronary heart disease -- Patient outcomes, Coronary heart disease -- Risk factors, Diabetes -- Complications and side effects, Diabetes -- Patient outcomes, Health
Published
2004

126. Effect of vorapaxar on myocardial infarction in the thrombin receptor antagonist for clinical event reduction in acute coronary syndrome (TRA·CER) trial

Author

Leonardi, Sergio, Tricoci, Pierluigi, White, Harvey D., Armstrong, Paul W., Huang, Zhen, Wallentin, Lars, Aylward, Philip E., Moliterno, David J., Van de Werf, Frans, Chen, Edmond, Providencia, Luis, Nordrehaug, Jan E., Held, Claes, Strony, John, Rorick, Tyrus L., Harrington, Robert A., and Mahaffey, Kenneth W.

Published
2013
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127. Increased mortality among patients taking digoxin—analysis from the AFFIRM study

Author

Whitbeck, Matthew G., Charnigo, Richard J., Khairy, Paul, Ziada, Khaled, Bailey, Alison L., Zegarra, Milagros M., Shah, Jignesh, Morales, Gustavo, Macaulay, Tracy, Sorrell, Vincent L., Campbell, Charles L., Gurley, John, Anaya, Paul, Nasr, Hafez, Bai, Rong, Di Biase, Luigi, Booth, David C., Jondeau, Guillaume, Natale, Andrea, Roy, Denis, Smyth, Susan, Moliterno, David J., and Elayi, Claude S.

Published
2013
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134. Prognostic importance of physical examination for heart failure in non-ST-elevation acute coronary syndromes: the enduring value of Killip classification

Author

Khot, Umesh N., Jia, Gang, Moliterno, David J., Lincoff, A. Michael, Khot, Monica B., Harrington, Robert A., and Topol, Eric J.

Subjects
Heart failure -- Health aspects, Heart attack -- Prognosis
Abstract

The Killip classification system can accurately predict which patients with a non-ST-segment heart attack may die within the following year, according to a study of 26,090 patients. Those in Killip class 3 or 4 had higher 30-day and six-month death rates than those in Killip class 1 or 2. The Killip classification is used to indicate a patient's degree of heart failure. Killip 1 or 2 indicates no heart failure or mild heart failure and Killip 3 or 4 indicates moderate to severe heart failure.

Published
2003

138. Third universal definition of myocardial infarction

Author

Thygesen, Kristian, Alpert, Joseph S., Jaffe, Allan S., Simoons, Maarten L., Chaitman, Bernard R., White, Harvey D., Thygesen, Kristian, Alpert, Joseph S., White, Harvey D., Jaffe, Allan S., Katus, Hugo A., Apple, Fred S., Lindahl, Bertil, Morrow, David A., Chaitman, Bernard R., Clemmensen, Peter M., Johanson, Per, Hod, Hanoch, Underwood, Richard, Bax, Jeroen J., Bonow, Robert O., Pinto, Fausto, Gibbons, Raymond J., Fox, Keith A., Atar, Dan, Newby, L. Kristin, Galvani, Marcello, Hamm, Christian W., Uretsky, Barry F., Gabriel Steg, Ph., Wijns, William, Bassand, Jean-Pierre, Menasché, Phillippe, Ravkilde, Jan, Ohman, E. Magnus, Antman, Elliott M., Wallentin, Lars C., Armstrong, Paul W., Simoons, Maarten L., Januzzi, James L., Nieminen, Markku S., Gheorghiade, Mihai, Filippatos, Gerasimos, Luepker, Russell V., Fortmann, Stephen P., Rosamond, Wayne D., Levy, Dan, Wood, David, Smith, Sidney C., Hu, Dayi, Lopez-Sendon, José-Luis, Robertson, Rose Marie, Weaver, Douglas, Tendera, Michal, Bove, Alfred A., Parkhomenko, Alexander N., Vasilieva, Elena J., Mendis, Shanti, Bax, Jeroen J., Baumgartner, Helmut, Ceconi, Claudio, Dean, Veronica, Deaton, Christi, Fagard, Robert, Funck-Brentano, Christian, Hasdai, David, Hoes, Arno, Kirchhof, Paulus, Knuuti, Juhani, Kolh, Philippe, McDonagh, Theresa, Moulin, Cyril, Popescu, Bogdan A., Reiner, Željko, Sechtem, Udo, Sirnes, Per Anton, Tendera, Michal, Torbicki, Adam, Vahanian, Alec, Windecker, Stephan, Morais, Joao, Aguiar, Carlos, Almahmeed, Wael, Arnar, David O., Barili, Fabio, Bloch, Kenneth D., Bolger, Ann F., Bøtker, Hans Erik, Bozkurt, Biykem, Bugiardini, Raffaele, Cannon, Christopher, de Lemos, James, Eberli, Franz R., Escobar, Edgardo, Hlatky, Mark, James, Stefan, Kern, Karl B., Moliterno, David J., Mueller, Christian, Neskovic, Aleksandar N., Pieske, Burkert Mathias, Schulman, Steven P., Storey, Robert F., Taubert, Kathryn A., Vranckx, Pascal, and Wagner, Daniel R.

Published
2012
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140. 2012 ACCF/AATS/SCAI/STS expert consensus document on transcatheter aortic valve replacement: Developed in collabration with the American Heart Association, American Society of Echocardiography, European Association for Cardio-Thoracic Surgery, Heart Failure Society of America, Mended Hearts, Society of Cardiovascular Anesthesiologists, Society of Cardiovascular Computed Tomography, and Society for Cardiovascular Magnetic Resonance

Author

Holmes, David R., Jr., Mack, Michael J., Kaul, Sanjay, Agnihotri, Arvind, Alexander, Karen P., Bailey, Steven R., Calhoon, John H., Carabello, Blase A., Desai, Milind Y., Edwards, Fred H., Francis, Gary S., Gardner, Timothy J., Kappetein, Pieter A., Linderbaum, Jane A., Mukherjee, Chirojit, Mukherjee, Debabrata, Otto, Catherine M., Ruiz, Carlos E., Sacco, Ralph L., Smith, Donnette, Thomas, James D., Harrington, Robert A., Bhatt, Deepak L., Ferrari, Victor A., Fisher, John D., Garcia, Mario J., Gentile, Federico, Gilson, Michael F., Hernandez, Adrian F., Jacobs, Alice K., Moliterno, David J., and Weitz, Howard H.

Published
2012
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147. Promise of combined low-molecular-weight heparin and platelet glycoprotein IIb/IIIa inhibition: results from Platelet IIb/IIIa Antagonist for the Reduction of Acute coronary syndrome events in a Global Organization Network B (PARAGON B)

Author

Mukherjee, Debabrata, Mahaffey, Kenneth W., Moliterno, David J., Harrington, Robert A., Yadav, Jay S., Pieper, Karen S., Gallup, Dianne, Dyke, Christopher, Roe, Matthew T., Berdan, Lisa, Lauer, Michael S., Manttari, Matti, White, Harvey D., Califf, Robert M., and Topol, Eric J.

Subjects
Heart attack -- Drug therapy, Unstable angina -- Drug therapy, Anticoagulants (Medicine) -- Evaluation, Health
Published
2002

150. Early statin initiation and outcomes in patients with acute coronary syndromes. (Original Contribution)

Author

Newby, L. Kristin, Kristinsson, Arni, Bhapkar, Manjushri V., Aylward, Philip E., Dimas, Alexios P., Klein, Werner W., McGuire, Darren K., Moliterno, David J., Verheugt, Freek W. A., Weaver, W. Douglas, and Califf, Robert M.

Subjects
Heart attack -- Drug therapy, Unstable angina -- Drug therapy, Anticholesteremic agents -- Evaluation
Abstract

A group of cholesterol-lowering drugs called statins do not appear to benefit patients who have had a heart attack or unstable angina. This was the conclusion of a study of 12,365 patients, half of whom began taking statins and half of whom did not. Ninety-day and one-year mortality rates were the same in both groups., Context: The secondary prevention benefit of therapy with 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors (statins) has been clearly demonstrated; however, the role of early initiation of statins after acute coronary syndromes (ACSs) is unknown. Objective: To evaluate the association of early statin initiation ([less than or equal to]7 days) after ACS with 90-day and 1-year outcomes. Design: Observational cohort from databases of 2 randomized clinical trials, SYMPHONY and 2nd SYMPHONY. Setting: Nine hundred thirty-one clinical centers in 37 countries. Patients: A total of 12365 ACS patients randomized from August 1997 to August 1999 who were not taking statins prior to the index ACS and who either started statin therapy early (median, 2.0 [interquartile range, 1.0-3.1] days after ACS; n=3952) or survived more than 5 days after ACS and never received statin therapy (n=8413). Main Outcome Measures: Ninety-day incidence of death; death or myocardial infarction (MI); and death, MI, or severe recurrent ischemia; as well as 1-year incidence of death. Results: Ninety-day and 1-year unadjusted mortality comparison suggested early statin benefit (1.2% for early statins vs 2.1% for no statins; hazard ratio [HR], 0.58; 95% confidence interval [CI] 0.42-0.81 for 90-day comparisons and 2.3% for early statins vs 4.4% for no statins; HR, 0.52; 95% CI, 0.40-0.68 for 1-year comparison). However, no benefit was evident for 90-day death or Ml (6.5% vs 6.9%; HR, 0.95; 95% CI, 0.82-1.11) or death, MI, or severe recurrent ischemia (9.2% vs 8.9%; HR, 1.04; 95% CI, 0.92-1.18). After propensity and covariate adjustment, there were no 90-day or 1-year differences between the early-statin group and the no-statin group. The 90-day adjusted HR for death was 1.08 (95% CI, 0.75-1.56); for death or MI, 1.08 (95% CI, 0.91-1.29); and for death, MI, or severe recurrent ischemia, 1.15 (95% CI, 0.99-1.34). One-year mortality-adjusted HR was 0.99 (95% CI, 0.73-1.33). Among 2711 patients with core laboratory lipid analysis, early statin was associated with higher adjusted risk for death o r death or MI at cholesterol levels below treatment guidelines but was more favorable at higher levels. Conclusions: In this study, there was no relationship between early initiation of statin therapy and improved outcomes although our subset analysis suggests that outcomes after early statin initiation may vary with cholesterol levels. Confirmation of early treatment effects of statins on outcomes awaits the results of adequately powered randomized clinical trials.

Published
2002

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