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626 results on '"Miyagawa, Kazuya"'

101. d-Mannose-appended 5,15-diazaporphyrin for photodynamic therapy

Author

Ali, Lamiaa M. A., primary, Miyagawa, Kazuya, additional, Fukui, Norihito, additional, Onofre, Mélanie, additional, El Cheikh, Khaled, additional, Morère, Alain, additional, Clément, Sébastien, additional, Gary-Bobo, Magali, additional, Richeter, Sébastien, additional, and Shinokubo, Hiroshi, additional

Published
2022
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105. DOCK2 is involved in the host genetics and biology of severe COVID-19

Author

Namkoong, Ho, Edahiro, Ryuya, Takano, Tomomi, Nishihara, Hiroshi, Shirai, Yuya, Sonehara, Kyuto, Tanaka, Hiromu, Azekawa, Shuhei, Mikami, Yohei, Lee, Ho, Hasegawa, Takanori, Okudela, Koji, Okuzaki, Daisuke, Motooka, Daisuke, Kanai, Masahiro, Naito, Tatsuhiko, Yamamoto, Kenichi, Wang, Qingbo S., Saiki, Ryunosuke, Ishihara, Rino, Matsubara, Yuta, Hamamoto, Junko, Hayashi, Hiroyuki, Yoshimura, Yukihiro, Tachikawa, Natsuo, Yanagita, Emmy, Hyugaji, Takayoshi, Shimizu, Eigo, Katayama, Kotoe, Kato, Yasuhiro, Morita, Takayoshi, Takahashi, Kazuhisa, Harada, Norihiro, Naito, Toshio, Hiki, Makoto, Matsushita, Yasushi, Takagi, Haruhi, Aoki, Ryousuke, Nakamura, Ai, Harada, Sonoko, Sasano, Hitoshi, Kabata, Hiroki, Masaki, Katsunori, Kamata, Hirofumi, Ikemura, Shinnosuke, Chubachi, Shotaro, Okamori, Satoshi, Terai, Hideki, Morita, Atsuho, Asakura, Takanori, Sasaki, Junichi, Morisaki, Hiroshi, Uwamino, Yoshifumi, Nanki, Kosaku, Uchida, Sho, Uno, Shunsuke, Nishimura, Tomoyasu, Ishiguro, Takashi, Isono, Taisuke, Shibata, Shun, Matsui, Yuma, Hosoda, Chiaki, Takano, Kenji, Nishida, Takashi, Kobayashi, Yoichi, Takaku, Yotaro, Takayanagi, Noboru, Ueda, Soichiro, Tada, Ai, Miyawaki, Masayoshi, Yamamoto, Masaomi, Yoshida, Eriko, Hayashi, Reina, Nagasaka, Tomoki, Arai, Sawako, Kaneko, Yutaro, Sasaki, Kana, Tagaya, Etsuko, Kawana, Masatoshi, Arimura, Ken, Takahashi, Kunihiko, Anzai, Tatsuhiko, Ito, Satoshi, Endo, Akifumi, Uchimura, Yuji, Miyazaki, Yasunari, Honda, Takayuki, Tateishi, Tomoya, Tohda, Shuji, Ichimura, Naoya, Sonobe, Kazunari, Sassa, Chihiro Tani, Nakajima, Jun, Nakano, Yasushi, Nakajima, Yukiko, Anan, Ryusuke, Arai, Ryosuke, Kurihara, Yuko, Harada, Yuko, Nishio, Kazumi, Ueda, Tetsuya, Azuma, Masanori, Saito, Ryuichi, Sado, Toshikatsu, Miyazaki, Yoshimune, Sato, Ryuichi, Haruta, Yuki, Nagasaki, Tadao, Yasui, Yoshinori, Hasegawa, Yoshinori, Mutoh, Yoshikazu, Kimura, Tomoki, Sato, Tomonori, Takei, Reoto, Hagimoto, Satoshi, Noguchi, Yoichiro, Yamano, Yasuhiko, Sasano, Hajime, Ota, Sho, Nakamori, Yasushi, Yoshiya, Kazuhisa, Saito, Fukuki, Yoshihara, Tomoyuki, Wada, Daiki, Iwamura, Hiromu, Kanayama, Syuji, Maruyama, Shuhei, Yoshiyama, Takashi, Ohta, Ken, Kokuto, Hiroyuki, Ogata, Hideo, Tanaka, Yoshiaki, Arakawa, Kenichi, Shimoda, Masafumi, Osawa, Takeshi, Tateno, Hiroki, Hase, Isano, Yoshida, Shuichi, Suzuki, Shoji, Kawada, Miki, Horinouchi, Hirohisa, Saito, Fumitake, Mitamura, Keiko, Hagihara, Masao, Ochi, Junichi, Uchida, Tomoyuki, Baba, Rie, Arai, Daisuke, Ogura, Takayuki, Takahashi, Hidenori, Hagiwara, Shigehiro, Nagao, Genta, Konishi, Shunichiro, Nakachi, Ichiro, Murakami, Koji, Yamada, Mitsuhiro, Sugiura, Hisatoshi, Sano, Hirohito, Matsumoto, Shuichiro, Kimura, Nozomu, Ono, Yoshinao, Baba, Hiroaki, Suzuki, Yusuke, Nakayama, Sohei, Masuzawa, Keita, Namba, Shinichi, Suzuki, Ken, Naito, Yoko, Liu, Yu-Chen, Takuwa, Ayako, Sugihara, Fuminori, Wing, James B., Sakakibara, Shuhei, Hizawa, Nobuyuki, Shiroyama, Takayuki, Miyawaki, Satoru, Kawamura, Yusuke, Nakayama, Akiyoshi, Matsuo, Hirotaka, Maeda, Yuichi, Nii, Takuro, Noda, Yoshimi, Niitsu, Takayuki, Adachi, Yuichi, Enomoto, Takatoshi, Amiya, Saori, Hara, Reina, Yamaguchi, Yuta, Murakami, Teruaki, Kuge, Tomoki, Matsumoto, Kinnosuke, Yamamoto, Yuji, Yamamoto, Makoto, Yoneda, Midori, Kishikawa, Toshihiro, Yamada, Shuhei, Kawabata, Shuhei, Kijima, Noriyuki, Takagaki, Masatoshi, Sasa, Noah, Ueno, Yuya, Suzuki, Motoyuki, Takemoto, Norihiko, Eguchi, Hirotaka, Fukusumi, Takahito, Imai, Takao, Fukushima, Munehisa, Kishima, Haruhiko, Inohara, Hidenori, Tomono, Kazunori, Kato, Kazuto, Takahashi, Meiko, Matsuda, Fumihiko, Hirata, Haruhiko, Takeda, Yoshito, Koh, Hidefumi, Manabe, Tadashi, Funatsu, Yohei, Ito, Fumimaro, Fukui, Takahiro, Shinozuka, Keisuke, Kohashi, Sumiko, Miyazaki, Masatoshi, Shoko, Tomohisa, Kojima, Mitsuaki, Adachi, Tomohiro, Ishikawa, Motonao, Takahashi, Kenichiro, Inoue, Takashi, Hirano, Toshiyuki, Kobayashi, Keigo, Takaoka, Hatsuyo, Watanabe, Kazuyoshi, Miyazawa, Naoki, Kimura, Yasuhiro, Sado, Reiko, Sugimoto, Hideyasu, Kamiya, Akane, Kuwahara, Naota, Fujiwara, Akiko, Matsunaga, Tomohiro, Sato, Yoko, Okada, Takenori, Hirai, Yoshihiro, Kawashima, Hidetoshi, Narita, Atsuya, Niwa, Kazuki, Sekikawa, Yoshiyuki, Nishi, Koichi, Nishitsuji, Masaru, Tani, Mayuko, Suzuki, Junya, Nakatsumi, Hiroki, Ogura, Takashi, Kitamura, Hideya, Hagiwara, Eri, Murohashi, Kota, Okabayashi, Hiroko, Mochimaru, Takao, Nukaga, Shigenari, Satomi, Ryosuke, Oyamada, Yoshitaka, Mori, Nobuaki, Baba, Tomoya, Fukui, Yasutaka, Odate, Mitsuru, Mashimo, Shuko, Makino, Yasushi, Yagi, Kazuma, Hashiguchi, Mizuha, Kagyo, Junko, Shiomi, Tetsuya, Fuke, Satoshi, Saito, Hiroshi, Tsuchida, Tomoya, Fujitani, Shigeki, Takita, Mumon, Morikawa, Daiki, Yoshida, Toru, Izumo, Takehiro, Inomata, Minoru, Kuse, Naoyuki, Awano, Nobuyasu, Tone, Mari, Ito, Akihiro, Nakamura, Yoshihiko, Hoshino, Kota, Maruyama, Junichi, Ishikura, Hiroyasu, Takata, Tohru, Odani, Toshio, Amishima, Masaru, Hattori, Takeshi, Shichinohe, Yasuo, Kagaya, Takashi, Kita, Toshiyuki, Ohta, Kazuhide, Sakagami, Satoru, Koshida, Kiyoshi, Hayashi, Kentaro, Shimizu, Tetsuo, Kozu, Yutaka, Hiranuma, Hisato, Gon, Yasuhiro, Izumi, Namiki, Nagata, Kaoru, Ueda, Ken, Taki, Reiko, Hanada, Satoko, Kawamura, Kodai, Ichikado, Kazuya, Nishiyama, Kenta, Muranaka, Hiroyuki, Nakamura, Kazunori, Hashimoto, Naozumi, Wakahara, Keiko, Koji, Sakamoto, Omote, Norihito, Ando, Akira, Kodama, Nobuhiro, Kaneyama, Yasunari, Maeda, Shunsuke, Kuraki, Takashige, Matsumoto, Takemasa, Yokote, Koutaro, Nakada, Taka-Aki, Abe, Ryuzo, Oshima, Taku, Shimada, Tadanaga, Harada, Masahiro, Takahashi, Takeshi, Ono, Hiroshi, Sakurai, Toshihiro, Shibusawa, Takayuki, Kimizuka, Yoshifumi, Kawana, Akihiko, Sano, Tomoya, Watanabe, Chie, Suematsu, Ryohei, Sageshima, Hisako, Yoshifuji, Ayumi, Ito, Kazuto, Takahashi, Saeko, Ishioka, Kota, Nakamura, Morio, Masuda, Makoto, Wakabayashi, Aya, Watanabe, Hiroki, Ueda, Suguru, Nishikawa, Masanori, Chihara, Yusuke, Takeuchi, Mayumi, Onoi, Keisuke, Shinozuka, Jun, Sueyoshi, Atsushi, Nagasaki, Yoji, Okamoto, Masaki, Ishihara, Sayoko, Shimo, Masatoshi, Tokunaga, Yoshihisa, Kusaka, Yu, Ohba, Takehiko, Isogai, Susumu, Ogawa, Aki, Inoue, Takuya, Fukuyama, Satoru, Eriguchi, Yoshihiro, Yonekawa, Akiko, Kan-o, Keiko, Matsumoto, Koichiro, Kanaoka, Kensuke, Ihara, Shoichi, Komuta, Kiyoshi, Inoue, Yoshiaki, Chiba, Shigeru, Yamagata, Kunihiro, Hiramatsu, Yuji, Kai, Hirayasu, Asano, Koichiro, Oguma, Tsuyoshi, Ito, Yoko, Hashimoto, Satoru, Yamasaki, Masaki, Kasamatsu, Yu, Komase, Yuko, Hida, Naoya, Tsuburai, Takahiro, Oyama, Baku, Takada, Minoru, Kanda, Hidenori, Kitagawa, Yuichiro, Fukuta, Tetsuya, Miyake, Takahito, Yoshida, Shozo, Ogura, Shinji, Abe, Shinji, Kono, Yuta, Togashi, Yuki, Takoi, Hiroyuki, Kikuchi, Ryota, Ogawa, Shinichi, Ogata, Tomouki, Ishihara, Shoichiro, Kanehiro, Arihiko, Ozaki, Shinji, Fuchimoto, Yasuko, Wada, Sae, Fujimoto, Nobukazu, Nishiyama, Kei, Terashima, Mariko, Beppu, Satoru, Yoshida, Kosuke, Narumoto, Osamu, Nagai, Hideaki, Ooshima, Nobuharu, Motegi, Mitsuru, Umeda, Akira, Miyagawa, Kazuya, Shimada, Hisato, Endo, Mayu, Ohira, Yoshiyuki, Watanabe, Masafumi, Inoue, Sumito, Igarashi, Akira, Sato, Masamichi, Sagara, Hironori, Tanaka, Akihiko, Ohta, Shin, Kimura, Tomoyuki, Shibata, Yoko, Tanino, Yoshinori, Nikaido, Takefumi, Minemura, Hiroyuki, Sato, Yuki, Yamada, Yuichiro, Hashino, Takuya, Shinoki, Masato, Iwagoe, Hajime, Takahashi, Hiroshi, Fujii, Kazuhiko, Kishi, Hiroto, Kanai, Masayuki, Imamura, Tomonori, Yamashita, Tatsuya, Yatomi, Masakiyo, Maeno, Toshitaka, Hayashi, Shinichi, Takahashi, Mai, Kuramochi, Mizuki, Kamimaki, Isamu, Tominaga, Yoshiteru, Ishii, Tomoo, Utsugi, Mitsuyoshi, Ono, Akihiro, Tanaka, Toru, Kashiwada, Takeru, Fujita, Kazue, Saito, Yoshinobu, Seike, Masahiro, Watanabe, Hiroko, Matsuse, Hiroto, Kodaka, Norio, Nakano, Chihiro, Oshio, Takeshi, Hirouchi, Takatomo, Makino, Shohei, Egi, Moritoki, Matsuda, Koichi, Yamanashi, Yuji, Furukawa, Yoichi, Morisaki, Takayuki, Murakami, Yoshinori, Kamatani, Yoichiro, Muto, Kaori, Nagai, Akiko, Obara, Wataru, Yamaji, Ken, Asai, Satoshi, Takahashi, Yasuo, Suzuki, Takao, Sinozaki, Nobuaki, Yamaguchi, Hiroki, Minami, Shiro, Murayama, Shigeo, Yoshimori, Kozo, Nagayama, Satoshi, Obata, Daisuke, Higashiyama, Masahiko, Masumoto, Akihide, Koretsune, Yukihiro, Omae, Yosuke, Nannya, Yasuhito, Ueno, Takafumi, Katayama, Kazuhiko, Ai, Masumi, Fukui, Yoshinori, Kumanogoh, Atsushi, Sato, Toshiro, Hasegawa, Naoki, Tokunaga, Katsushi, Ishii, Makoto, Koike, Ryuji, Kitagawa, Yuko, Kimura, Akinori, Imoto, Seiya, Miyano, Satoru, Ogawa, Seishi, Kanai, Takanori, Fukunaga, Koichi, and Okada, Yukinori

Subjects
Genome-wide association studies, Japan, Genetics research, Weight Loss, Immunogenetics, Animals, Guanine Nucleotide Exchange Factors, Humans, Genetic Predisposition to Disease, RNA-Seq, Lung, Alleles, Multidisciplinary, Host Microbial Interactions, Mesocricetus, SARS-CoV-2, Macrophages, GTPase-Activating Proteins, COVID-19, Pneumonia, Middle Aged, Viral Load, Disease Models, Animal, Viral infection, Interferon Type I, Pyrazoles, Genome-Wide Association Study
Abstract

Identifying the host genetic factors underlying severe COVID-19 is an emerging challenge. Here we conducted a genome-wide association study (GWAS) involving 2, 393 cases of COVID-19 in a cohort of Japanese individuals collected during the initial waves of the pandemic, with 3, 289 unaffected controls. We identified a variant on chromosome 5 at 5q35 (rs60200309-A), close to the dedicator of cytokinesis 2 gene (DOCK2), which was associated with severe COVID-19 in patients less than 65 years of age. This risk allele was prevalent in East Asian individuals but rare in Europeans, highlighting the value of genome-wide association studies in non-European populations. RNA-sequencing analysis of 473 bulk peripheral blood samples identified decreased expression of DOCK2 associated with the risk allele in these younger patients. DOCK2 expression was suppressed in patients with severe cases of COVID-19. Single-cell RNA-sequencing analysis (n = 61 individuals) identified cell-type-specific downregulation of DOCK2 and a COVID-19-specific decreasing effect of the risk allele on DOCK2 expression in non-classical monocytes. Immunohistochemistry of lung specimens from patients with severe COVID-19 pneumonia showed suppressed DOCK2 expression. Moreover, inhibition of DOCK2 function with CPYPP increased the severity of pneumonia in a Syrian hamster model of SARS-CoV-2 infection, characterized by weight loss, lung oedema, enhanced viral loads, impaired macrophage recruitment and dysregulated type I interferon responses. We conclude that DOCK2 has an important role in the host immune response to SARS-CoV-2 infection and the development of severe COVID-19, and could be further explored as a potential biomarker and/or therapeutic target., 「コロナ制圧タスクフォース」COVID-19疾患感受性遺伝子DOCK2の重症化機序を解明 --アジア最大のバイオレポジトリーでCOVID-19の治療標的を発見--. 京都大学プレスリリース. 2022-08-10.

Published
2021

109. RNA Sequencing Analysis Detection of a Novel Pathway of Endothelial Dysfunction in Pulmonary Arterial Hypertension

Author

Rhodes, Christopher J., Im, Hogune, Cao, Aiqin, Hennigs, Jan K., Wang, Lingli, Sa, Silin, Chen, Pin-I, Nickel, Nils P., Miyagawa, Kazuya, Hopper, Rachel K., Tojais, Nancy F., Li, Caiyun G., Gu, Mingxia, Spiekerkoetter, Edda, Xian, Zhaoying, Chen, Rui, Zhao, Mingming, Kaschwich, Mark, del Rosario, Patricia A., Bernstein, Daniel, Zamanian, Roham T., Wu, Joseph C., Snyder, Michael P., and Rabinovitch, Marlene

Published
2015
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114. Effects of Gadolinium Deposition in the Brain on Motor or Behavioral Function: A Mouse Model

Author

Akai, Hiroyuki, primary, Miyagawa, Kazuya, additional, Takahashi, Kohei, additional, Mochida-Saito, Atsumi, additional, Kurokawa, Kazuhiro, additional, Takeda, Hiroshi, additional, Tsuji, Minoru, additional, Sugawara, Haruto, additional, Yasaka, Koichiro, additional, Kunimatsu, Akira, additional, Inoue, Yusuke, additional, Abe, Osamu, additional, Ohtomo, Kuni, additional, and Kiryu, Shigeru, additional

Published
2021
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120. Tenosynovial and Cardiac Transthyretin Amyloidosis in Japanese Patients Undergoing Carpal Tunnel Release

Author

Sugiura, Kenta, primary, Kozuki, Hiroki, additional, Ueba, Hiroaki, additional, Kubo, Toru, additional, Ochi, Yuri, additional, Baba, Yuichi, additional, Miyagawa, Kazuya, additional, Noguchi, Tatsuya, additional, Hirota, Takayoshi, additional, Yamasaki, Naohito, additional, Wada, Noriko, additional, Nakashima, Junko, additional, Murakami, Ichiro, additional, Ikeuchi, Masahiko, additional, and Kitaoka, Hiroaki, additional

Published
2021
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121. Japan COVID-19 Task Force: a nation-wide consortium to elucidate host genetics of COVID-19 pandemic in Japan

Author

Namkoong, Ho, primary, Edahiro, Ryuya, additional, Fukunaga, Koichi, additional, Shirai, Yuya, additional, Sonehara, Kyuto, additional, Tanaka, Hiromu, additional, Lee, Ho, additional, Hasegawa, Takanori, additional, Kanai, Masahiro, additional, Naito, Tatsuhiko, additional, Yamamoto, Kenichi, additional, Saiki, Ryunosuke, additional, Hyugaji, Takayoshi, additional, Shimizu, Eigo, additional, Katayama, Kotoe, additional, Takahashi, Kazuhisa, additional, Harada, Norihiro, additional, Naito, Toshio, additional, Hiki, Makoto, additional, Matsushita, Yasushi, additional, Takagi, Haruhi, additional, Aoki, Ryousuke, additional, Nakamura, Ai, additional, Harada, Sonoko, additional, Sasano, Hitoshi, additional, Kabata, Hiroki, additional, Masaki, Katsunori, additional, Kamata, Hirofumi, additional, Ikemura, Shinnosuke, additional, Chubachi, Shotaro, additional, Okamori, Satoshi, additional, Terai, Hideki, additional, Morita, Atsuho, additional, Asakura, Takanori, additional, Sasaki, Junichi, additional, Morisaki, Hiroshi, additional, Uwamino, Yoshifumi, additional, Nanki, Kosaku, additional, Mikami, Yohei, additional, Uchida, Sho, additional, Uno, Shunsuke, additional, Ishihara, Rino, additional, Matsubara, Yuta, additional, Nishimura, Tomoyasu, additional, Ogawa, Takanori, additional, Ishiguro, Takashi, additional, Isono, Taisuke, additional, Shibata, Shun, additional, Matsui, Yuma, additional, Hosoda, Chiaki, additional, Takano, Kenji, additional, Nishida, Takashi, additional, Kobayashi, Yoichi, additional, Takaku, Yotaro, additional, Takayanagi, Noboru, additional, Ueda, Soichiro, additional, Tada, Ai, additional, Miyawaki, Masayoshi, additional, Yamamoto, Masaomi, additional, Yoshida, Eriko, additional, Hayashi, Reina, additional, Nagasaka, Tomoki, additional, Arai, Sawako, additional, Kaneko, Yutaro, additional, Sasaki, Kana, additional, Tagaya, Etsuko, additional, Kawana, Masatoshi, additional, Arimura, Ken, additional, Takahashi, Kunihiko, additional, Anzai, Tatsuhiko, additional, Ito, Satoshi, additional, Endo, Akifumi, additional, Uchimura, Yuji, additional, Miyazaki, Yasunari, additional, Honda, Takayuki, additional, Tateishi, Tomoya, additional, Tohda, Shuji, additional, Ichimura, Naoya, additional, Sonobe, Kazunari, additional, Sassa, Chihiro, additional, Nakajima, Jun, additional, Nakano, Yasushi, additional, Nakajima, Yukiko, additional, Anan, Ryusuke, additional, Arai, Ryosuke, additional, Kurihara, Yuko, additional, Harada, Yuko, additional, Nishio, Kazumi, additional, Ueda, Tetsuya, additional, Azuma, Masanori, additional, Saito, Ryuichi, additional, Sado, Toshikatsu, additional, Miyazaki, Yoshimune, additional, Sato, Ryuichi, additional, Haruta, Yuki, additional, Nagasaki, Tadao, additional, Yasui, Yoshinori, additional, Hasegawa, Yoshinori, additional, Mutoh, Yoshikazu, additional, Sato, Tomonori, additional, Takei, Reoto, additional, Hagimoto, Satoshi, additional, Noguchi, Yoichiro, additional, Yamano, Yasuhiko, additional, Sasano, Hajime, additional, Ota, Sho, additional, Nakamori, Yasushi, additional, Yoshiya, Kazuhisa, additional, Saito, Fukuki, additional, Yoshihara, Tomoyuki, additional, Wada, Daiki, additional, Iwamura, Hiromu, additional, Kanayama, Syuji, additional, Maruyama, Shuhei, additional, Yoshiyama, Takashi, additional, Ohta, Ken, additional, Kokuto, Hiroyuki, additional, Ogata, Hideo, additional, Tanaka, Yoshiaki, additional, Arakawa, Kenichi, additional, Shimoda, Masafumi, additional, Osawa, Takeshi, additional, Tateno, Hiroki, additional, Hase, Isano, additional, Yoshida, Shuichi, additional, Suzuki, Shoji, additional, Kawada, Miki, additional, Horinouchi, Hirohisa, additional, Saito, Fumitake, additional, Mitamura, Keiko, additional, Hagihara, Masao, additional, Ochi, Junichi, additional, Uchida, Tomoyuki, additional, Baba, Rie, additional, Arai, Daisuke, additional, Ogura, Takayuki, additional, Takahashi, Hidenori, additional, Hagiwara, Shigehiro, additional, Nagao, Genta, additional, Konishi, Shunichiro, additional, Nakachi, Ichiro, additional, Murakami, Koji, additional, Yamada, Mitsuhiro, additional, Sugiura, Hisatoshi, additional, Sano, Hirohito, additional, Matsumoto, Shuichiro, additional, Kimura, Nozomu, additional, Ono, Yoshinao, additional, Baba, Hiroaki, additional, Suzuki, Yusuke, additional, Nakayama, Sohei, additional, Masuzawa, Keita, additional, Namba, Shinichi, additional, Suzuki, Ken, additional, Hizawa, Nobuyuki, additional, Shiroyama, Takayuki, additional, Miyawaki, Satoru, additional, Kawamura, Yusuke, additional, Nakayama, Akiyoshi, additional, Matsuo, Hirotaka, additional, Maeda, Yuichi, additional, Nii, Takuro, additional, Noda, Yoshimi, additional, Niitsu, Takayuki, additional, Adachi, Yuichi, additional, Enomoto, Takatoshi, additional, Amiya, Saori, additional, Hara, Reina, additional, Kishikawa, Toshihiro, additional, Yamada, Shuhei, additional, Kawabata, Shuhei, additional, Kijima, Noriyuki, additional, Takagaki, Masatoshi, additional, Sasa, Noa, additional, Ueno, Yuya, additional, Suzuki, Motoyuki, additional, Takemoto, Norihiko, additional, Eguchi, Hirotaka, additional, Fukusumi, Takahito, additional, Imai, Takao, additional, Fukushima, Munehisa, additional, Kishima, Haruhiko, additional, Inohara, Hidenori, additional, Tomono, Kazunori, additional, Kato, Kazuto, additional, Takahashi, Meiko, additional, Matsuda, Fumihiko, additional, Hirata, Haruhiko, additional, Takeda, Yoshito, additional, Koh, Hidefumi, additional, Manabe, Tadashi, additional, Funatsu, Yohei, additional, Ito, Fumimaro, additional, Fukui, Takahiro, additional, Shinozuka, Keisuke, additional, Kohashi, Sumiko, additional, Miyazaki, Masatoshi, additional, Shoko, Tomohisa, additional, Kojima, Mitsuaki, additional, Adachi, Tomohiro, additional, Ishikawa, Motonao, additional, Takahashi, Kenichiro, additional, Inoue, Takashi, additional, Hirano, Toshiyuki, additional, Kobayashi, Keigo, additional, Takaoka, Hatsuyo, additional, Watanabe, Kazuyoshi, additional, Miyazawa, Naoki, additional, Kimura, Yasuhiro, additional, Sado, Reiko, additional, Sugimoto, Hideyasu, additional, Kamiya, Akane, additional, Kuwahara, Naota, additional, Fujiwara, Akiko, additional, Matsunaga, Tomohiro, additional, Sato, Yoko, additional, Okada, Takenori, additional, Hirai, Yoshihiro, additional, Kawashima, Hidetoshi, additional, Narita, Atsuya, additional, Niwa, Kazuki, additional, Sekikawa, Yoshiyuki, additional, Nishi, Koichi, additional, Nishitsuji, Masaru, additional, Tani, Mayuko, additional, Suzuki, Junya, additional, Nakatsumi, Hiroki, additional, Ogura, Takashi, additional, Kitamura, Hideya, additional, Hagiwara, Eri, additional, Murohashi, Kota, additional, Okabayashi, Hiroko, additional, Mochimaru, Takao, additional, Nukaga, Shigenari, additional, Satomi, Ryosuke, additional, Oyamada, Yoshitaka, additional, Mori, Nobuaki, additional, Baba, Tomoya, additional, Fukui, Yasutaka, additional, Odate, Mitsuru, additional, Mashimo, Shuko, additional, Makino, Yasushi, additional, Yagi, Kazuma, additional, Hashiguchi, Mizuha, additional, Kagyo, Junko, additional, Shiomi, Tetsuya, additional, Fuke, Satoshi, additional, Saito, Hiroshi, additional, Tsuchida, Tomoya, additional, Fujitani, Shigeki, additional, Takita, Mumon, additional, Morikawa, Daiki, additional, Yoshida, Toru, additional, Izumo, Takehiro, additional, Inomata, Minoru, additional, Kuse, Naoyuki, additional, Awano, Nobuyasu, additional, Tone, Mari, additional, Ito, Akihiro, additional, Nakamura, Yoshihiko, additional, Hoshino, Kota, additional, Maruyama, Junichi, additional, Ishikura, Hiroyasu, additional, Takata, Tohru, additional, Odani, Toshio, additional, Amishima, Masaru, additional, Hattori, Takeshi, additional, Shichinohe, Yasuo, additional, Kagaya, Takashi, additional, Kita, Toshiyuki, additional, Ohta, Kazuhide, additional, Sakagami, Satoru, additional, Koshida, Kiyoshi, additional, Hayashi, Kentaro, additional, Shimizu, Tetsuo, additional, Kozu, Yutaka, additional, Hiranuma, Hisato, additional, Gon, Yasuhiro, additional, Izumi, Namiki, additional, Nagata, Kaoru, additional, Ueda, Ken, additional, Taki, Reiko, additional, Hanada, Satoko, additional, Kawamura, Kodai, additional, Ichikado, Kazuya, additional, Nishiyama, Kenta, additional, Muranaka, Hiroyuki, additional, Nakamura, Kazunori, additional, Hashimoto, Naozumi, additional, Wakahara, Keiko, additional, Koji, Sakamoto, additional, Omote, Norihito, additional, Ando, Akira, additional, Kodama, Nobuhiro, additional, Kaneyama, Yasunari, additional, Maeda, Shunsuke, additional, Kuraki, Takashige, additional, Matsumoto, Takemasa, additional, Yokote, Koutaro, additional, Nakada, Taka-Aki, additional, Abe, Ryuzo, additional, Oshima, Taku, additional, Shimada, Tadanaga, additional, Harada, Masahiro, additional, Takahashi, Takeshi, additional, Ono, Hiroshi, additional, Sakurai, Toshihiro, additional, Shibusawa, Takayuki, additional, Kimizuka, Yoshifumi, additional, Kawana, Akihiko, additional, Sano, Tomoya, additional, Watanabe, Chie, additional, Suematsu, Ryohei, additional, Sageshima, Hisako, additional, Yoshifuji, Ayumi, additional, Ito, Kazuto, additional, Takahashi, Saeko, additional, Ishioka, Kota, additional, Nakamura, Morio, additional, Masuda, Makoto, additional, Wakabayashi, Aya, additional, Watanabe, Hiroki, additional, Ueda, Suguru, additional, Nishikawa, Masanori, additional, Chihara, Yusuke, additional, Takeuchi, Mayumi, additional, Onoi, Keisuke, additional, Shinozuka, Jun, additional, Sueyoshi, Atsushi, additional, Nagasaki, Yoji, additional, Okamoto, Masaki, additional, Ishihara, Sayoko, additional, Shimo, Masatoshi, additional, Tokunaga, Yoshihisa, additional, Kusaka, Yu, additional, Ohba, Takehiko, additional, Isogai, Susumu, additional, Ogawa, Aki, additional, Inoue, Takuya, additional, Fukuyama, Satoru, additional, Eriguchi, Yoshihiro, additional, Yonekawa, Akiko, additional, Kan-o, Keiko, additional, Matsumoto, Koichiro, additional, Kanaoka, Kensuke, additional, Ihara, Shoichi, additional, Komuta, Kiyoshi, additional, Inoue, Yoshiaki, additional, Chiba, Shigeru, additional, Yamagata, Kunihiro, additional, Hiramatsu, Yuji, additional, Kai, Hirayasu, additional, Asano, Koichiro, additional, Oguma, Tsuyoshi, additional, Ito, Yoko, additional, Hashimoto, Satoru, additional, Yamasaki, Masaki, additional, Kasamatsu, Yu, additional, Komase, Yuko, additional, Hida, Naoya, additional, Tsuburai, Takahiro, additional, Oyama, Baku, additional, Takada, Minoru, additional, Kanda, Hidenori, additional, Kitagawa, Yuichiro, additional, Fukuta, Tetsuya, additional, Miyake, Takahito, additional, Yoshida, Shozo, additional, Ogura, Shinji, additional, Abe, Shinji, additional, Kono, Yuta, additional, Togashi, Yuki, additional, Takoi, Hiroyuki, additional, Kikuchi, Ryota, additional, Ogawa, Shinichi, additional, Ogata, Tomouki, additional, Ishihara, Shoichiro, additional, Kanehiro, Arihiko, additional, Ozaki, Shinji, additional, Fuchimo, Yasuko, additional, Wada, Sae, additional, Fujimoto, Nobukazu, additional, Nishiyama, Kei, additional, Terashima, Mariko, additional, Beppu, Satoru, additional, Yoshida, Kosuke, additional, Narumoto, Osamu, additional, Nagai, Hideaki, additional, Ooshima, Nobuharu, additional, Motegi, Mitsuru, additional, Umeda, Akira, additional, Miyagawa, Kazuya, additional, Shimada, Hisato, additional, Endo, Mayu, additional, Ohira, Yoshiyuki, additional, Watanabe, Masafumi, additional, Inoue, Sumito, additional, Igarashi, Akira, additional, Sato, Masamichi, additional, Sagara, Hironori, additional, Tanaka, Akihiko, additional, Ohta, Shin, additional, Kimura, Tomoyuki, additional, Shibata, Yoko, additional, Tanino, Yoshinori, additional, Nikaido, Takefumi, additional, Minemura, Hiroyuki, additional, Sato, Yuki, additional, Yamada, Yuichiro, additional, Hashino, Takuya, additional, Shinoki, Masato, additional, Iwagoe, Hajime, additional, Takahashi, Hiroshi, additional, Fujii, Kazuhiko, additional, Kishi, Hiroto, additional, Kanai, Masayuki, additional, Imamura, Tomonori, additional, Yamashita, Tatsuya, additional, Yatomi, Masakiyo, additional, Maeno, Toshitaka, additional, Hayashi, Shinichi, additional, Takahashi, Mai, additional, Kuramochi, Mizuki, additional, Kamimaki, Isamu, additional, Tominaga, Yoshiteru, additional, Ishii, Tomoo, additional, Utsugi, Mitsuyoshi, additional, Ono, Akihiro, additional, Tanaka, Toru, additional, Kashiwada, Takeru, additional, Fujita, Kazue, additional, Saito, Yoshinobu, additional, Seike, Masahiro, additional, Omae, Yosuke, additional, Nannya, Yasuhito, additional, Ueno, Takafumi, additional, Takano, Tomomi, additional, Katayama, Kazuhiko, additional, Ai, Masumi, additional, Kumanogoh, Atsushi, additional, Sato, Toshiro, additional, Hasegawa, Naoki, additional, Tokunaga, Katsushi, additional, Ishii, Makoto, additional, Koike, Ryuji, additional, Kitagawa, Yuko, additional, Kimura, Akinori, additional, Imoto, Seiya, additional, Miyano, Satoru, additional, Ogawa, Seishi, additional, Kanai, Takanori, additional, and Okada, Yukinori, additional

Published
2021
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122. New insights about the structural properties of κ-(BEDT-TTF)2X2(CN)3 (X=Cu and Ag) Spin Liquids

Author

Foury-Leylekian, Pascale, Ilakovac, Vita, Fertey, Pierre, Balédent, Victor, Milat, Ognjen, Miyagawa, Kazuya, Kanoda, Kazushi, Hiramatsu, Takaaki, Yoshida, Yukihiro, Saito, Gunzi, Alemany i Cahner, Pere, Canadell, Enric, 1950, Tomic, Silvia, and Pouget, Jean-Paul

Subjects
Centrifugació, Condensed Matter::Strongly Correlated Electrons, Centrifugation, Liquids, X-rays diffraction, Difracció de raigs X, Líquids
Abstract

Here, the first accurate study is presented of the room-temperature and 100 K structures of one of the first organic spin liquids, 􏰗-(BEDT-TTF)2Ag2(CN)3. It is shown that the monoclinic structure determined previously is only the average one. It is shown that the exact structure presents triclinic symmetry with two non-equivalent dimers in the unit cell. But surprisingly this does not lead to a sizeable charge disproportionation between dimers. The difference from the analogue compound 􏰗-(BEDT-TTF)2Cu2(CN)3 which also presents a spin liquid phase is discussed in detail. The data provided here show the importance of the anionic layer and in particular the transition metal position in the process of symmetry breaking. The possible impact of the symmetry breaking, albeit weak, on the spin-liquid mechanism and the influence of various disorders on the physical properties of this system is also discussed.

Published
2020

123. Site-selective halogenation on meso-mesityl substituents of 10,20-dimesityl-5,15-diazaporphyrins with an AuX3/AgOTf combination

Author

Longevial, Jean-François, Miyagawa, Kazuya, Shinokubo, Hiroshi, Longevial, Jean-François, Miyagawa, Kazuya, and Shinokubo, Hiroshi

Abstract

We have developed site-selective bromination on the mesityl substituents of 10,20-dimesityl-5,15-diazaporphyrins. Treatment of 10,20-dimesityl-5,15-diazaporphyrin and its nickel(II) complex with a combination of AuBr3/AgOTf induced selective bromination on the mesityl groups. These brominated products can be employed for late-stage modification of the aryl substituents.

Published
2021

124. PPARγ-p53-Mediated Vasculoregenerative Program to Reverse Pulmonary Hypertension

Author

Hennigs, Jan K., primary, Cao, Aiqin, additional, Li, Caiyun G., additional, Shi, Minyi, additional, Mienert, Julia, additional, Miyagawa, Kazuya, additional, Körbelin, Jakob, additional, Marciano, David P., additional, Chen, Pin-I, additional, Roughley, Matthew, additional, Elliott, Matthew V., additional, Harper, Rebecca L., additional, Bill, Matthew A., additional, Chappell, James, additional, Moonen, Jan-Renier, additional, Diebold, Isabel, additional, Wang, Lingli, additional, Snyder, Michael P., additional, and Rabinovitch, Marlene, additional

Published
2021
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127. Endogenous Retroviral Elements Generate Pathologic Neutrophils and Elastase Rich Exosomes in Pulmonary Arterial Hypertension

Author

Taylor, Shalina, primary, Contrepois, Kévin, additional, Benayoun, Bérénice A., additional, Jiang, Lihua, additional, Isobe, Sarasa, additional, Wang, Lingli, additional, Melemenidis, Stavros, additional, Ozen, Mehmet O., additional, Otsuki, Shoichiro, additional, Shinohara, Tsutomu, additional, Sweatt, Andrew J., additional, Kaplan, Jordan, additional, Cao, Aiqin, additional, Moonen, Jan-Renier, additional, Marciano, David P., additional, Gu, Mingxia, additional, Miyagawa, Kazuya, additional, Del Rosario, Patricia A., additional, Hsi, Andrew, additional, Thompson, A. A. Roger, additional, Ariza, Maria-Eugenia, additional, Demirci, Utkan, additional, Zamanian, Roham T., additional, Haddad, Francois, additional, Nicolls, Mark R., additional, Snyder, Michael P., additional, and Rabinovitch, Marlene, additional

Published
2021
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136. New insights into the structural properties of κ-(BEDT-TTF)2Ag2(CN)3spin liquid

Author

Foury-Leylekian, Pascale, primary, Ilakovac, Vita, additional, Fertey, Pierre, additional, Baledent, Victor, additional, Milat, Ognjen, additional, Miyagawa, Kazuya, additional, Kanoda, Kazushi, additional, Hiramatsu, Takaaki, additional, Yoshida, Yukihiro, additional, Saito, Gunzi, additional, Alemany, Pere, additional, Canadell, Enric, additional, Tomic, Silvia, additional, and Pouget, Jean-Paul, additional

Published
2020
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142. New insights into the structural properties of j-(BEDT-TTF)2Ag2(CN)3 spin liquid

Author

Ministerio de Ciencia, Innovación y Universidades (España), Ministerio de Economía y Competitividad (España), Generalitat de Catalunya, Japan Society for the Promotion of Science, Foury-Leylekian, Pascale, Ilakovac, Vita, Fertey, Pierre, Baledent, Victor, Milat, Ognjen, Miyagawa, Kazuya, Kanoda, Kazushi, Hiramatsu, Takaaki, Yoshida, Yukihiro, Saito, Gunzi, Alemany, Pere, Canadell, Enric, Tomic, Silvia, Pouget, Jean-Paul, Ministerio de Ciencia, Innovación y Universidades (España), Ministerio de Economía y Competitividad (España), Generalitat de Catalunya, Japan Society for the Promotion of Science, Foury-Leylekian, Pascale, Ilakovac, Vita, Fertey, Pierre, Baledent, Victor, Milat, Ognjen, Miyagawa, Kazuya, Kanoda, Kazushi, Hiramatsu, Takaaki, Yoshida, Yukihiro, Saito, Gunzi, Alemany, Pere, Canadell, Enric, Tomic, Silvia, and Pouget, Jean-Paul

Abstract

Here, the first accurate study is presented of the room-temperature and 100 K structures of one of the first organic spin liquids, -(BEDT-TTF)2Ag2(CN)3. It is shown that the monoclinic structure determined previously is only the average one. It is shown that the exact structure presents triclinic symmetry with two non-equivalent dimers in the unit cell. But surprisingly this does not lead to a sizeable charge disproportionation between dimers. The difference from the analogue compound -(BEDT-TTF)2Cu2(CN)3 which also presents a spin liquid phase is discussed in detail. The data provided here show the importance of the anionic layer and in particular the transition metal position in the process of symmetry breaking. The possible impact of the symmetry breaking, albeit weak, on the spin-liquid mechanism and the influence of various disorders on the physical properties of this system is also discussed.

Published
2020

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