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The objective of this research was to create Tolbutamide extended-release (ER) tablets and evaluate their efficacy in comparison to the gold standard, hydrophobic polymer (HPC). The natural polymers that were considered for this study included guar gum, xanthan gum, acacia gum, and fenugreek mucilage. The mechanical characteristics, drug release patterns, and stability under accelerated settings of tablets produced employing direct compression at different polymer concentrations (25%, 50%, and 75%) were studied. With a release rate of 94.5 percent over 24 hours, the optimized formulation (TF6 with 75% Guar gum) offered the best sustained drug release. As for controlled-release qualities, Xanthan gum showed promise with a cumulative release of 93.45% and Acacia gum was dependable, though not quite as efficient. Fenugreek mucilage was not well suited for endotracheal formulations due to its rapid drug release. The optimized formulation (TF6) kept its mechanical integrity, drug content, and constant drug release profile throughout three months at 40°C/75% RH, according to stability testing. This study offers additional evidence that natural polymers, specifically Guar gum can effectively replace synthetic binders in sustained-release formulations. Additional research should explore alternative combinations of these natural binders to enhance formulation efficacy. [ABSTRACT FROM AUTHOR]

The equimolar reaction between 1,9-bis(N,N-dimethylaminomethyl)-5,5′-diphenyldipyrromethane, H2L1 or 1,9-bis(3,5-dimethylpyrazolylmethyl)-5,5′-diethyldipyrromethane, H2L2 and [NiCl2(DME)] in the presence of KH yielded the neutral mononuclear nickel(II) complexes [Ni(L1)-κ4N,N,N,N], 1 and [Ni(L2)-κ4N,N,N,N], 2, respectively. Their X-ray structures revealed the formation of triple chelation by the ligand in both structures with quite different nickel(II)-surrounded square planar geometries owing to the steric difference between –NMe2 and 3,5-dimethylpyrazolyl groups. While the –NMe2 group substituted ligand L1 afforded nickel complex 1 with a plane of symmetry, 3,5-dimethylpyrazole substituted L2 rendered helical chirality in the structure of complex 2. Both the enantiomers (Δ and Λ) of complex 2 were observed in the crystal lattice. Their solution state behaviors were consistent with the solid-state structures as monitored by 1H NMR spectroscopy. Both the enantiomers of complex 2 were present in a dynamic equilibrium in solution and studied by variable temperature 1H NMR spectroscopy. Similar to the chiral complex, the corresponding ligand H2L2 also exhibited chirality as shown by its crystal structure and the two ligand enantiomers participated in a very fast dynamic interconversion, which became slower upon metalation. [ABSTRACT FROM AUTHOR]

Biodiesel, a promising alternative to traditional petroleum fuels, is a green energy solution. Photocatalysis is a facile, novel, economic, and efficient approach to biodiesel synthesis. Metal sulfides have been used extensively for various photocatalytic applications. The present study demonstrates, for the first time, the photocatalytic production of biodiesel using a novel metal sulfide‐based heterogeneous photocatalyst under visible light irradiation. A nano zero‐valent silver doped hydroxyapatite (Ag/HAp) was synthesized using a green bio‐reductant technique and decorated with tin sulfide nanoparticles (SnS2/Ag/HAp or SAH) for photocatalytic biodiesel synthesis. The hydroxyapatite (HAp) was extracted from waste fish scales to minimize the use of chemicals and to utilize waste for useful applications. The prepared SAH photocatalyst was characterized through X‐ray diffraction, UV‐visible diffuse reflectance spectroscopy, photoluminescence spectroscopy, Fourier transform infrared analysis, energy dispersive X‐ray analysis, scanning electron microscopy, high‐resolution transmission electron microscopy and X‐ray photoelectron spectroscopy analysis. The effect of reaction parameters was optimized, and under optimum conditions of 1 wt% photocatalyst loading, and 8:1 methanol‐to‐oleic‐acid ratio, for 60 min, a high yield of 98.0 ± 0.61% could be achieved using a SAH photocatalyst. Scavenger tests indicated the simultaneous generation of photoinduced electrons and holes necessary for photocatalytic biodiesel synthesis. A mechanism for the photocatalytic esterification reaction of oleic acid is proposed. The synthesized SnS2‐based photocatalyst could be easily recoverable and reusable for five consecutive runs, which can replace traditional industrial heterogeneous catalysts in the near future. [ABSTRACT FROM AUTHOR]

This paper presents a new time-domain multi-objective function approach for solving load frequency control issue in an interconnected power system. The performance of interconnected power system in each area is validated for overshoot and settling time values of frequency change and tie-line power exchange. An objective function is created with the goal of enhancing proportional integral derivative (PID) controller settings by reducing overshoot and achieving faster time-domain settling times. The efficiency of the proposed time-domain multi-objective function is evaluated in a twoarea thermal power plant using a nature-inspired cuckoo search optimization (CSA) technique. By comparing the time-domain simulation results of the test system with the existing integral error-based objective functions IAE, ISE, ITAE, and ITSE, the proposed objective function is validated. Further, a sensitivity analysis were carried out to analyze the robustness of the proposed multi-objective function under various uncertain conditions. [ABSTRACT FROM AUTHOR]

This article explores two examples of worker housing in India, and compares these with China's 'dormitory labour regime', arguing that these methods of labour accommodation are part of a broader, increasingly global, workplace-residence regime aimed at migrant labour control for the purposes of value extraction. Contrary to previous studies, it argues that China's system is not unique, but part of the political economy of contemporary global capitalism. Although there exist historical and contextual variations between the two Indian case studies, drawn from the Delhi National Capital Region (NCR) garment sector and the Andhra Pradesh electronics industry, as well as between the Indian and Chinese contexts, the aims and many of the outcomes are similar. Moving beyond a focus on the country- and space-specific 'dormitory labour regime' facilitates a broader understanding of the crucial role contemporary workplace-residence systems play in enhancing control of migrant labour for the benefit of global accumulation networks. [ABSTRACT FROM AUTHOR]