226 results on '"Mingyang Xu"'
Search Results
102. Ca2+ mediates transcription factor PuDof2.5 and suppresses stone cell production in pear fruits.
- Author
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He Zhang, Siyang Gao, Tianye Wang, Mingyang Xu, Xinyue Li, and Guodong Du
- Subjects
PEARS ,TRANSCRIPTION factors ,FRUIT ripening ,FRUIT ,LIGNINS ,GENE targeting - Abstract
Stone cells are sclerenchyma cells formed by deposition of lignin, which is the most significant factor limiting the quality of pears. Ca
2+ was known to inhibit stone cells in pear fruits, but the underlying molecular mechanism remains unclear. Our study revealed that exogenous CaCl2 (Ca2+ ) treatment of “Nanguo” pear (Pyrus ussuriensis) suppressed the synthesis of lignin and stone cell production. We further analysed the transcriptomes using RNA-seq, identified a transcription factor, PuDof2.5, and its targets gene PuPRX42-like (lignin polymerase gene) expression decreased in CaCl2-treated samples, which are involved in suppressing lignin biosynthesis in pear fruit. PuDof2.5 was found to bind directly to the PuPRX42-like promoter and induced its transcription. Taken together, our results revealed that Ca2+ modulated the key lignin biosynthetic transcription factor PuDof2.5 to suppress stone cell production in pear fruits. [ABSTRACT FROM AUTHOR]- Published
- 2022
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103. RNA-Sequencing Analysis of the Viral Community in Yellow Catfish (Pelteobagrus fulvidraco) in the Upper Reaches of the Yangtze River
- Author
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Wenzhi Liu, Huiwu Tian, Jie Ma, Mingyang Xue, Yong Zhou, Mengmeng Li, Jingwen Jiang, Yuding Fan, and Mingdian Liu
- Subjects
Yangtze River ,yellow catfish ,Pelteobagrus fulvidraco ,viral community ,RNA sequencing ,genetic diversity ,Veterinary medicine ,SF600-1100 ,Zoology ,QL1-991 - Abstract
Different viruses are abundant in aquatic ecosystems. There has been limited research on the viral communities in the upper reaches of the Yangtze River. Yellow catfish (Pelteobagrus fulvidraco), an important economic fish that is widely distributed in the upper reaches of the Yangtze River, was selected as the research object. Using RNA sequencing, we identified 11 viruses belonging to the Adintoviridae, Tombusviridae, Caudovirales, Microviridae, Picornavirales, and other bacteriophage families. The predominant viral families/order in Luzhou (LZ), Fuling (FL), and Wanzhou (WZ) were Caudovirales, Adinoviridae, and Microviridae, respectively. The virome from WZ had a unique community composition, with a high abundance of Picornavirales compared with LZ and FL. In LZ, the predominant double-stranded RNA virus family was Siphoviridae. Phylogenetic analyses showed that viruses presented high genetic diversity. Phylogenetically, Wenling pleuronectiformes picornavirus was close to the family Caliciviridae, which includes yellow catfish calicivirus (YcCV), responsible for the massive mortality of yellow catfish in 2020. This study provides insights into the viral community composition in yellow catfish in the upper reaches of the Yangtze River, revealing a diverse and unique river water virome and providing clues for future research on the origin of viral pathogens.
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- 2024
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104. A Data Synchronization Method for Relay Protection in Active Distribution Network
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Yiqing Liu, Mingyang Xu, Weicong Gao, and Guobin Chen
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Computer science ,Protective relay ,Sampling (statistics) ,Fault detection and isolation ,law.invention ,Relay ,law ,Synchronization (computer science) ,Line (geometry) ,Electronic engineering ,Data synchronization ,MATLAB ,computer ,computer.programming_language - Abstract
It is difficult for the current differential protection to realize synchronous sampling in active distribution network. In order to deal with this problem, a novel data synchronization method based on zero-crossing point of pre-fault current is proposed in this paper. The influencing factors of the synchronization method are discussed in detail, including line capacitance current, line length and sampling time difference. The performance of zero-crossing data synchronization method is verified by simulation in PSCAD and MATLAB. The simulation results show that the proposed method can effectively realize the data synchronization under various conditions in active distribution network.
- Published
- 2020
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105. Research on XLPE Insulation Failure Characteristics of DC Cables in Fire Environmet
- Author
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Duan Cheng, Mingyang Xu, Zheng Jiankang, Su Xiaoting, Gong Qiming, and Hai Nan
- Subjects
Materials science ,INSULATION FAILURE ,Electric field ,Electric breakdown ,Field strength ,Composite material ,Conductivity ,Temperature measurement - Abstract
In order to study the insulation performance of DC XLPE cables in fire environment, the conductivity of XLPE used in DC cable was tested at different temperatures, and the breakdown field strength of XLPE at different high temperatures was measured, which was carried out in a high-temperature oven. Meanwhile, the field strength distribution inside the DC cable under high temperature environment was simulated. The research results show that long-term overload of XLPE cable or high ambient temperature can cause the electric field strength of the cable insulation to increase, which will induce various defects and eventually cause insulation breakdown.
- Published
- 2020
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106. Nutrient deposition over the past 60 years in a reservoir within a medium-sized agricultural catchment
- Author
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Shujian Xu, Decheng Zhang, Zengli Pei, Tong Wu, Bao Li, Yunqi Zhang, Zhehong Wu, Xue Lu, and Mingyang Xu
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Hydrology ,chemistry.chemical_classification ,geography ,Agricultural catchment ,Environmental Engineering ,geography.geographical_feature_category ,010504 meteorology & atmospheric sciences ,Environmental change ,Drainage basin ,Sediment ,010501 environmental sciences ,01 natural sciences ,Pollution ,Deposition (geology) ,Nutrient ,chemistry ,Environmental Chemistry ,Environmental science ,Organic matter ,Catchment area ,Waste Management and Disposal ,0105 earth and related environmental sciences - Abstract
Widespread dam construction has reduced the hydrological connectivity of catchments of various sizes. Nutrients lost from upper catchments can be intercepted by dams and deposited in reservoir sediments, and this reduces downstream nutrient transportation. Few previous studies have assessed historical nutrient deposition rates (NDRs) in man-made reservoirs. Using 137Cs and 210Pbex deposition chronologies, this paper examines the total nitrogen (TN), total phosphate (TP), and organic matter (OM) concentrations in six sediment cores recovered from Xujiaya reservoir (catchment area 580 km2), provides estimates of historical NDRs by referencing the original capacity curve, and explores temporal changes to the NDR since dam construction. The results show that anthropogenic sources resulted in the increase in nutrient concentrations in the upper parts of the cores, whereas natural sources were the main contributors to nutrient deposition across the whole reservoir. In addition, sediment supply from the catchment was the main source of the nutrients deposited in the reservoir, and the changing patterns of NDRs were overall regulated by sediment yields. The TN, TP, and OM profiles in the six cores, together with the historical NDRs, reflect the pattern of nutrient deposition in the reservoir derived from this agricultural catchment over the past 60 years. The results provide new insight into the effect of dam construction on nutrient deposition at a medium-sized catchment scale against a background of recent environmental change influenced by human activity.
- Published
- 2020
107. Glycitin Suppresses Cartilage Destruction of Osteoarthritis in Mice
- Author
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Yunpeng Zhao, Wenhan Wang, Jiangfan Peng, Hao Li, Xin Pan, Mingyang Xu, Jiayi Li, Minfa Zhang, and Ruitong Yang
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0301 basic medicine ,Male ,medicine.medical_specialty ,medicine.medical_treatment ,Immunology ,Inflammation ,Phytoestrogens ,Osteoarthritis ,03 medical and health sciences ,Mice ,0302 clinical medicine ,In vivo ,Internal medicine ,medicine ,Immunology and Allergy ,Animals ,Cells, Cultured ,business.industry ,Anterior Cruciate Ligament Injuries ,medicine.disease ,Isoflavones ,Rheumatology ,In vitro ,Mice, Inbred C57BL ,030104 developmental biology ,Cytokine ,Cartilage ,Mechanism of action ,030220 oncology & carcinogenesis ,Cancer research ,medicine.symptom ,Signal transduction ,business - Abstract
Osteoarthritis (OA), a chronic joint disease, is characterized by cartilage surface erosion, subchondral bone rebuilding, and formation of osteophytes. To date, the nosogenesis and underlying mechanisms of OA have not yet been elucidated. However, it is widely accepted that TNF-α is a crucial cytokine in the development of OA. Glycitin, a natural isoflavone extracted from legumes, affects physiological reactions and pathological responses. Recently, the anti-inflammatory effect of glycitin has been reported. However, the function of glycitin in cartilage degeneration in OA remains to be investigated. In the current study, primary murine chondrocytes were isolated and stimulated by TNF-α to evaluate the anti-inflammatory effects and protective function of glycitin in chondrocytes. In vivo, the ACLT mouse model, a frequently-used OA model, was used to further examine the therapeutic role of glycitin in cartilage degeneration and inflammation in OA. Consequently, glycitin functions were examined both in vivo and in vitro. Moreover, the underlying mechanism of action of glycitin was investigated and was found to involve the NF-κB signaling pathway. Collectively, this study suggests that glycitin can be potentially used for the treatment of joint degenerative diseases, including OA.
- Published
- 2020
108. Colloidal Surface Engineering: Growth of Layered Double Hydroxides with Intrinsic Oxidase-Mimicking Activities to Fight Against Bacterial Infection in Wound Healing
- Author
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Weiwei Li, Mingyang Xu, Yuanming Li, Wenhan Wang, Yangtao Shangguan, Jiangfan Peng, Zhijie Yang, Shuping Wang, Yunpeng Zhao, Huiying Wei, Jingjing Wei, Gege Ouyang, and Wendi Zhang
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Biomedical Engineering ,Pharmaceutical Science ,02 engineering and technology ,Surface engineering ,engineering.material ,010402 general chemistry ,01 natural sciences ,Biomaterials ,Colloid ,Mice ,Hydroxides ,Animals ,Wound Healing ,Chemistry ,Layered double hydroxides ,Bacterial Infections ,021001 nanoscience & nanotechnology ,0104 chemical sciences ,Anti-Bacterial Agents ,Surface coating ,Chemical engineering ,Catalytic oxidation ,Nanocrystal ,engineering ,Nanorod ,0210 nano-technology ,Antibacterial activity ,Oxidoreductases - Abstract
Colloidal surface engineering is of particular importance to impart modular functionalities to the colloidal systems. Here, a layer of Mn/Ni layered hydroxides (Mn/Ni(OH)x LDHs) can be successfully coated on various colloidal particles, such as silica spheres, silica rods, ferrite nanocrystal supraparticles, as well as FeOOH nanorods. Such layered hydroxides have intrinsic oxidase-mimetic activities, as demonstrated by catalytic oxidation of tetramethyl benzidine in the presence of oxygen. Furthermore, Mn/Ni(OH)x LDHs structure seems to capture bacteria (both Gram positive and Gram negative) and exhibit antibacterial properties in vitro. Moreover, local delivery of Mn/Ni-LDH structure fights against infection and reverses delayed wound healing procedures in mice models. Importantly, such hierarchical structures may have strong adhesive properties to the bacteria, which may maximize the contact between Mn/Ni(OH)x LDHs and the bacteria's surface. Overall, the present versatile colloidal surface engineering strategy will bring new insights in the field of antibiotics for its high efficiency toward antibacterial activity.
- Published
- 2020
109. Phosphorylation of PLIN3 by AMPK promotes dispersion of lipid droplets during starvation
- Author
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Dan Liu, Zhou Songyang, Wenbin Ma, Mingyang Xu, Kejun Ying, Lisha Zhuang, Jianxi Zhu, Feng Liu, and Yi Liu
- Subjects
0301 basic medicine ,lcsh:Animal biochemistry ,AMP-Activated Protein Kinases ,Biochemistry ,Cell Line ,Perilipin-3 ,03 medical and health sciences ,0302 clinical medicine ,Lipid droplet ,Drug Discovery ,medicine ,Humans ,lcsh:QH573-671 ,lcsh:QP501-801 ,Starvation ,Extramural ,Chemistry ,lcsh:Cytology ,Fatty Acids ,AMPK ,Oxidation reduction ,Cell Biology ,Lipid Droplets ,Cell biology ,030104 developmental biology ,Phosphorylation ,medicine.symptom ,Dispersion (chemistry) ,Oxidation-Reduction ,030217 neurology & neurosurgery ,Biotechnology - Published
- 2018
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110. Influence of geometric parameters of surface electrode on electromechanical response of PDMS under impact loading
- Author
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Chang Liu, Yafei Han, Mengzhou Chang, Enling Tang, Liping He, Chuang Chen, Kai Guo, and Mingyang Xu
- Subjects
Materials science ,Polymers and Plastics ,Polydimethylsiloxane ,Yeoh ,Organic Chemistry ,SHPB system ,Numerical simulation ,Split-Hopkinson pressure bar ,Strain rate ,Viscoelasticity ,Strain gradient ,Stress (mechanics) ,chemistry.chemical_compound ,TP1080-1185 ,chemistry ,PDMS ,Electromechanical response ,Electrode ,Polymers and polymer manufacture ,Composite material ,Polarization (electrochemistry) - Abstract
In order to clarify the electromechanical coupling characteristics of polymer materials and extend their applications in MEMS (Micro-electromechanical Systems), electromechanical responses of PDMS (Polydimethylsiloxane) with different electrodes and thicknesses under different loading conditions have been performed experimentally and numerically. Basic electrical parameters measurement and quasi-static tensile experiment of PDMS specimens were conducted. Furthermore, the dynamic mechanical properties and polarization voltage of PDMS with different electrodes and thicknesses under different loading conditions have been studied by Split Hopkinson Pressure Bar (SHPB) system integrating with electrical output measuring system. Beyond that, Abaqus/Explicit numerical simulation of PDMS specimen under different loading conditions was carried out based on Yeoh viscoelastic model and Prony series, then the strain gradient and the flexoelectric coefficients were obtained. The results show that the maximum stress of PDMS increases with increasing of loading speed and decreases with increasing of thickness, the maximum polarization voltage increases with increasing of strain rate, the maximum polarization voltages of PDMS with “C” electrode and “+” electrode are about 14 times of that with circular electrode, the flexoelectric coefficients of PDMS are within the range of 10−11–10−9C/m.
- Published
- 2021
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111. Clinical efficacy of Danzhi Xiaoyao Powder in the treatment of post-stroke depression
- Author
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Min-Wang Guo, Chun-Qin Ding, Li Gao, Wu Xu, Xiao-Rong Wang, Jun Yao, and Mingyang Xu
- Subjects
Protocol (science) ,Research design ,medicine.medical_specialty ,business.industry ,General Medicine ,Citalopram ,medicine.disease ,law.invention ,Randomized controlled trial ,law ,Internal medicine ,mental disorders ,medicine ,Post-stroke depression ,Observational study ,Prospective cohort study ,business ,Stroke ,medicine.drug - Abstract
Background Depression is a common complication after stroke and is closely related to the poor prognosis of stroke. Antidepressants are the priority drug in the treatment of post-stroke depression (PSD), but there are dependence and adverse reactions. Danzhi Xiaoyao Powder has a good effect on depression without obvious adverse reactions. At present, there is a lack of rigorous randomized controlled trials to evaluate the clinical efficacy of Danzhi Xiaoyao Powder in the treatment of PSD. Methods This is a prospective, randomized, double-blind, parallel controlled trial to explore the efficacy and safety of Danzhi Xiaoyao Powder in the treatment of PSD. The participants were randomly divided into treatment group and control group. The treatment group used Danzhi Xiaoyao Powder combined with escitalopram oxalate, and the control group used Danzhi Xiaoyao Powder simulant combined with citalopram oxalate. The two groups were both treated for 8 weeks and followed up for 3 months. Observational index includes: Total response rate, Hamilton depression scale, Barthel index, national institutes of health stroke scale, the modified Edinburgh-Scandinavian stroke scale, Incidence of adverse reactions. Finally, SPASS 22.0 software was used for statistical analysis of the data. Discussion This study will evaluate the clinical efficacy of Danzhi Xiaoyao Powder in the treatment of PSD. The results of this study will provide reliable evidence for the clinical use of Xiaoyao Powder in the treatment of PSD. Trial registration Open Science Framework Registration number: DOI 10.17605/OSF.IO/5V926.
- Published
- 2021
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112. Theoretical and experimental study on the hypervelocity impact induced microjet from the grooved metal surface
- Author
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Weidong Song, Jian-Li Shao, Enling Tang, Pei Wang, Mingyang Xu, and Cheng Wang
- Subjects
Shock wave ,Materials science ,Mass distribution ,Projectile ,Mechanical Engineering ,Aerospace Engineering ,020101 civil engineering ,Ocean Engineering ,02 engineering and technology ,Mechanics ,Shadowgraphy ,0201 civil engineering ,law.invention ,Smoothed-particle hydrodynamics ,Bernoulli's principle ,020303 mechanical engineering & transports ,0203 mechanical engineering ,Mechanics of Materials ,law ,Automotive Engineering ,Light-gas gun ,Hypervelocity ,Safety, Risk, Reliability and Quality ,Civil and Structural Engineering - Abstract
The dynamic process of the hypervelocity impact induced microjet from the grooved metal surface is studied theoretically and experimentally. Based on shock wave theory and Bernoulli's equation, a physical model is proposed to theoretically analyze the formation process of the microjet and predict the spike (head) velocity of the microjet. The hypervelocity impact experiments of the cylindrical aluminum projectile on the metal target with grooves are conducted through two-stage light gas gun, and the sequence shadowgraphy images of the microjetting formation are recorded by using Ultra-high-speed camera. Then, the numerical simulations of the hypervelocity impact-induced microjet are performed by a self-developed SPH (smoothed particle hydrodynamics) code to examine the velocity distribution, mass distribution and density distribution in detail. These numerical results are compared with those obtained by experiments and theoretical analysis, which verifies the validity of numerical model. The numerical results reveal that the front of the shock wave generated by hypervelocity impact is not strictly planar in the target due to the shock wave releasing from both sides of the impact interface. Thus, the shape of the multiple jets generated from the grooves resembles a “trident”, and the upper microjet and the lower microjet deflect upward and downward respectively. The jetting velocity and mass of the middle microjet is larger than that of the microjets on both sides in the impact area. Last, the variation of the spike velocity and jetting mass with the impact velocity and the target thickness is obtained.
- Published
- 2021
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113. Characterization of the expression stability of largemouth bass (Micropterus salmoides) candidate reference genes by qRT-PCR during viral infection
- Author
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Yiqun Li, Jingjing Zhang, Mingyang Xue, Yong Zhou, Nan Jiang, Yan Meng, Chen Xu, Jinyu Shen, and Yuding Fan
- Subjects
Largemouth bass ,Micropterus salmoides ,Largemouth bass virus ,Reference genes ,Quantitative real-time PCR ,Microbiology ,QR1-502 ,Veterinary medicine ,SF600-1100 - Abstract
Quantitative Real-time PCR (qRT-PCR) is one of the most widely used methods for gene quantification because it is extremely sensitive, can be highly sequence specific, and has high precision while being easily reproducible in samples. The stability of the reference genes used for data normalization is crucial for exact experimental results and conclusions. In this study, qRT-PCR was used to analyze the expression of eight candidate reference genes including β-actin (ACTB), α-tubulin (TUBA), Elongation factor-1-α (EF1A), Glyceraldehyde-3-phosphate dehydrogenase (GAPDH1, GAPDH2), Hypoxanthine guanine phosphoribosyl transferase1 (HPRT), Ribosomal protein L7 (RPL7), and RNA polymerase II (RNA PoL Ⅱ) in largemouth bass. The expression and stability of above genes were evaluated among eight tissues with or without largemouth bass virus (LMBRaV) infection and assessed using BestKeeper, GeNorm, NormFinder statistical softwares and comparative Ct method, and then analyzed the comprehensive ranking by ReFinder. Our results showed that ACTB was identified as the most suitable genes of different tissues, while TUBA was ranked as the best reference gene in tissues infection with LMBRaV. To verify the screened reference genes, the expression pattern of IFN in spleen during LMBRaV infection was examined. This study provides useful information for gene expression characterization using qRT-PCR, which will benefit for future studies of gene regulation in largemouth bass.
- Published
- 2024
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114. The probiotic effects of host-associated Bacillus velezensis in diets for hybrid yellow catfish (Pelteobagrus fulvidraco ♀ × Pelteobagrus vachelli ♂)
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Zhehui Ji, Xing Lu, Mingyang Xue, Yuding Fan, Juan Tian, Lixue Dong, Chuanzhong Zhu, Hua Wen, and Ming Jiang
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Bacillus velezensis ,Probiotics ,Hybrid yellow catfish ,Intestinal health ,Liver metabolome ,Animal culture ,SF1-1100 - Abstract
This study was to evaluate the potential of a host-associated Bacillus velezensis as a probiotic for hybrid yellow catfish (Pelteobagrus fulvidraco ♀ × Pelteobagrus vachelli ♂). Diets (B0 to B5) containing 0, 0.90 × 108, 0.80 × 109, 0.85 × 1010, 0.90 × 1011, 0.83 × 1012 CFU/kg B. velezensis YFI-E109 were fed to the fish with initial weight (3.07 ± 0.08 g) in a recirculating aquaculture system for six weeks with three replicates, respectively. Probiotic effects were analyzed based on growth, body composition, liver and gut morphology, gut microbiome, and liver metabolome. Analysis of the bacterial genome has shown that the most abundant genes in B. velezensis YFI-E109 were distributed in carbohydrate and amino acid metabolism. Fish in groups B3 and B4 had better growth performance, and higher intestinal amylase (AMS) and lipase (LPS) activities compared with other groups (P
- Published
- 2023
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115. Pathological changes of highly pathogenic Bacillus cereus on Pelodiscus sinensis
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Zidong Xiao, Mengmeng Cheng, Xiaowei Hu, Mingyang Xue, Nan Jiang, Wei Liu, Yuding Fan, Yan Meng, Chen Xu, and Yong Zhou
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Chinese softshell turtle ,Trionyx sinensis ,histopathology ,bacterial load ,bacterial toxin ,gut microbiota ,Veterinary medicine ,SF600-1100 - Abstract
AbstractAn outbreak of a disease with a high mortality rate occurred in a Chinese Softshell Turtle (Pelodiscus sinensis) farm in Hubei Province. This study isolated a highly pathogenic Bacillus cereus strain (Y271) from diseased P. sinensis. Y271 has β hemolysis, containing both Hemolysin BL (hblA, hblC, and hblD), Non-hemolytic enterotoxin, NHE (nheA, nheB, and nheC), and Enterotoxin FM (entFM) genes. Y271 is highly pathogenic against P. sinensis with an LD50 = 6.80 × 103 CFU/g weight. B. cereus was detected in multiple tissues of the infected P. sinensis. Among them, spleen tissue showed the highest copy number density (1.54 ± 0.12 × 104 copies/mg). Multiple tissues and organs of diseased P. sinensis exhibited significant pathological damage, especially the spleen, liver, kidney, and intestine. It showed obvious tissue structure destruction, lesions, necrosis, red blood cells, and inflammatory cell infiltration. B. cereus proliferating in the spleen, liver, and other tissues was observed. The intestinal microbiota of the diseased P. sinensis was altered, with a greater abundance of Firmicutes, Fusobacterium, and Actinomyces than in the healthy group. Allobaculum, Rothia, Aeromonas, and Clostridium abundance were higher in the diseased group than in the healthy group. The number of unique microbial taxa (472) in the disease group was lower than that of the healthy group (705). Y271 was sensitive to multiple drugs, including florfenicol, enrofloxacin, neomycin, and doxycycline. B. cereus is the etiological agent responsible for the massive death of P. sinensis and reveals its potential risks during P. sinensis cultivation.
- Published
- 2023
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116. Properties of Jet-Plated Ni Coating on Ti Alloy (Ti6Al4V) with Laser Cleaning Pretreatment
- Author
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Muhammad Naveed Ahsan, Zhanwen Wang, Mingbo Qiu, Lida Shen, Xiao Wang, Zongjun Tian, Changjiang Wang, and Mingyang Xu
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lcsh:TN1-997 ,Materials science ,titanium alloy ,020209 energy ,Alloy ,Oxide ,02 engineering and technology ,friction properties ,engineering.material ,law.invention ,chemistry.chemical_compound ,Coating ,law ,Plating ,jet electrodeposition ,0202 electrical engineering, electronic engineering, information engineering ,General Materials Science ,Selective laser melting ,Composite material ,laser cleaning ,lcsh:Mining engineering. Metallurgy ,TA0401 ,Metals and Alloys ,Titanium alloy ,021001 nanoscience & nanotechnology ,Laser ,TA ,chemistry ,engineering ,0210 nano-technology ,Layer (electronics) - Abstract
The surface mechanical properties of the Selective Laser Melting (SLM) formed Ti6Al4V samples were improved by adopting a novel laser cleaning pretreatment process combined with a jet electrodeposition process. This paper aimed to investigate the effects of different laser powers on the morphologies and adhesions of the nickel coatings. The advantages of the laser cleaning process are no grinding, no contact, high efficiency and environmental protection. The morphologies, adhesion, wear resistance, and hardness of the coatings were characterized. The results indicate that when the laser energy density reached 20% (4 J/cm2), the contaminations on the substrate and the oxide layer were removed and the crystalline grain of the coating was 15.3 nm. The shallow pits generated by laser burning increased the adhesion of the coatings. In addition, when the laser energy density increased to 6 J/cm2, a yellow oxide layer was produced on the surface of the cleaned titanium alloy. Moreover, the wear resistance of the titanium alloy after the nickel plating was improved. The wear volume was only 0.046 mm3, and the hardness increased to 1967.6 N/mm2.
- Published
- 2019
117. On Calibration and Simulation of Local Volatility Model with Stochastic Interest Rate
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Mingyang Xu and Robert Berec
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Derivative (finance) ,Computer science ,media_common.quotation_subject ,Local volatility ,Convergence (routing) ,Econometrics ,Volatility smile ,Volatility (finance) ,Malliavin calculus ,Interest rate ,media_common ,Term (time) - Abstract
Local volatility model is a relatively simple way to capture volatility skew/smile. In spite of its drawbacks, it remains popular among practitioners for derivative pricing and hedging. For long-dated options or interest rate/equity hybrid products, in order to take into account the effect of stochastic interest rate on equity price volatility stochastic interest rate is often modelled together with stochastic equity price. Similar to local volatility model with deterministic interest rate, a forward Dupire PDE can be derived using Arrow-Debreu price method, which can then be shown to be equivalent to adding an additional correction term on top of Dupire forward PDE with deterministic interest rate. Calibrating a local volatility model by the forward Dupire PDE approach with adaptively mixed grids ensures both calibration accuracy and efficiency. Based on Malliavin calculus an accurate analytic approximation is also derived for the correction term incorporating impacts from both interest rate volatility and correlation, which integrates along a more likely straight line path for better accuracy. Eventually, the hybrid local volatility model can be calibrated in a two-step process, namely, calibrate local volatility model with deterministic interest rate and add adjustment for stochastic interest rate. Due to the lack of analytic solution and path-dependency nature of some products, Monte Carlo is a simple but flexible pricing method. In order to improve its convergence, we develop a scheme to combine merits of different simulation schemes and show its effectiveness.
- Published
- 2019
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118. Monte Carlo Calibration Method of Stochastic Volatility Model with Stochastic Interest Rate
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Mingyang Xu
- Subjects
Singular perturbation ,symbols.namesake ,Stochastic volatility ,Computer science ,Monte Carlo method ,Volatility smile ,symbols ,Applied mathematics ,Markov process ,Variance reduction ,Implied volatility ,Conditional expectation - Abstract
Implied volatility skew and smile are ubiquitous phenomena in the financial derivative market especially after the Black Monday 1987 crash. Various stochastic volatility models have been proposed to capture volatility skew and smile in derivative pricing and hedging. Almost 30 years after the advent of the first type of stochastic volatility model calibrating them to the market volatility surface still remains challenging, especially when stochastic interest rate has to be also taken into account for long-dated options. Many techniques have been applied to tackle this problem, including Fast Fourier Transform, singular perturbation expansion, heat kernel expansion, Markovian projection, to name a few. Although they have achieved some success in deriving either a close-form solution for a specific type of model or asymptotic solution in more general, none of them can really solve the calibration problem satisfying our need in term of both efficiency and accuracy. Monte Carlo method is a flexible numerical pricing method but has not been considering for calibration because of its slow convergence. However, with the great advance in computational power, in particular, parallel computation and the invention of other variance reduction techniques fast and accurate calibration using Monte Carlo becomes possible. This paper presents a Monte Carlo calibration method for stochastic volatility models with stochastic interest rate, which reduces simulation dimension by conditional expectation and further improves speed by vectorization. Numerical experiments show that both the calibration speed and accuracy of this generic method are satisfactory for almost all applications.
- Published
- 2019
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119. Identification of Aeromonas veronii as the Pathogen Associated with Massive Mortality in Bronze Gudgeon (Coreius heterodon)
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Wenzhi Liu, Mengmeng Li, Mingyang Xue, Yong Zhou, Nan Jiang, Yan Meng, Yisha Liu, Jingwen Jiang, Xiaolin Liao, and Yuding Fan
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bronze gudgeon (Coreius heterodon) ,Aeromonas veronii ,virulence genes ,blood parameters ,phylogenetic analysis ,Veterinary medicine ,SF600-1100 ,Zoology ,QL1-991 - Abstract
Aeromonas veronii, an opportunistic pathogen toward aquatic organisms, was identified as the causative pathogen (isolate WH10) in diseased bronze gudgeon via bacterial isolation, and morphological, physiological, biochemical, and molecular characterization. WH10 exerted its pathogenicity via five virulence genes, including those encoding cytotoxic enterotoxins (act and alt), lipase (lip), a quorum sensing-controlled virulence factor (LuxS), and a Type III secretion system inner membrane component (ascV). WH10 was shown to be sensitive to compound sulfamethoxazoles, cefothiophene, doxycycline, and sulfamethoxazole. Toward bronze gudgeon, WH10 had a median lethal dose (LD50) of 1.36 × 106 colony forming units/mL. Analysis of blood parameters of diseased fish revealed significant increases in monocytes and neutrophils, but decreased numbers of lymphocytes. Serum aspartate aminotransferase activity and triglyceride concentration were significantly higher in diseased fish than in healthy fish. The reverse was noted for alkaline phosphatase, total protein, albumin, total cholesterol, and glucose. Thus, Aeromonas veronii is implicated as the causative agent of the mass mortality observed in bronze gudgeon, warranting further investigations into the diagnosis, epidemiology, prevention, and treatment of this infectious disease.
- Published
- 2024
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120. Electrochemically-assisted deposition of toluidine blue-functionalized metal-organic framework films for electrochemical immunosensing of Indole-3-acetic acid
- Author
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Jianlong Yi, Xiaolan Yang, Yuanhua Shao, Daili Tang, Zhaohong Su, Hongmei Jiang, Siyu Xu, Mingyang Xu, Xiaoli Qin, Wenjing Xu, Yuqing Zhou, and Junjie Liu
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Detection limit ,Working electrode ,Microscope ,Chemistry ,Scanning electron microscope ,General Chemical Engineering ,fungi ,02 engineering and technology ,010402 general chemistry ,021001 nanoscience & nanotechnology ,Electrochemistry ,01 natural sciences ,0104 chemical sciences ,Analytical Chemistry ,law.invention ,chemistry.chemical_compound ,Transmission electron microscopy ,law ,Toluidine ,Thin film ,0210 nano-technology ,Nuclear chemistry - Abstract
A simple and rapid electrochemical synthesis strategy for in-situ fabrication of toluidine blue (TB)-functionalized metal organic framework (TB@MOFs) thin films via one-step reduction approach was reported. The TB@MOFs thin layer has been synthesized on the working electrode surface in different times at room temperature, and its morphology and thickness was characterized by varied instruments, including scanning electron microscope, transmission electron microscope, and scanning ion conductance microscope. The prepared TB@MOFs shows exceptional electrochemical activity and stability under mild conditions, and its electrochemical response is dependent on the amount of TB molecules which are encapsulated in the MOFs. Based on the TB@MOFs sensing platform, a sensitive label-free electrochemical immunosensor for the detection of Indole-3-acetic acid (IAA, a plant hormone) was developed with a wide linear range (2.5 pg mL−1 - 5 ng mL−1) and a low detection limit (1.4 pg mL−1). Moreover, this immune sensor shows good sensitivity and selectivity in real samples for IAA detection.
- Published
- 2021
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121. Antiviral effects of esculin on largemouth bass ranavirus in vivo and in vitro
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Mingyang Xue, Jingya Li, Yan Meng, Chen Xu, Nan Jiang, Yiqun Li, Yuding Fan, Liping Zhang, and Yong Zhou
- Subjects
Antiviral ,Largemouth bass ranavirus (LMBRaV) ,Esculin ,Largemouth bass ,Aquaculture. Fisheries. Angling ,SH1-691 - Abstract
Largemouth bass ranavirus (LMBRaV), a double-stranded DNA (dsDNA) virus, leads to considerable mortality and significant economic impacts in the largemouth bass (Micropterus salmoides) aquaculture sector. This study evaluated and screened compounds from Chinese herbs for their activity against LMBRaV. Esculin exhibited the highest rate (73 %) of inhibition on LMBRaV major capsid protein (MCP) gene expression at a concentration of 60 mg/L in a cellular environment. It also significantly reduced the cytopathic effect (CPE), protecting infected cells from LMBRaV-induced nuclear damage and hindering LMBRaV infection by modulating viral entry mechanisms. For in vivo study, esculin increased the survival rate of LMBRaV-infected largemouth bass by 60.0 % and 53.3 %, in prevention experiment and treatment experiment, respectively. Concurrently, esculin significantly reduced viral loads and induced the upregulation of antiviral-associated genes, indicating its potential for immunoregulation. In summary, esculin holds potential for both preventing and treating LMBRaV infections in the aquaculture context.
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- 2024
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122. Research on the Ionization Degree of the Plasma Generated by 2A12 Aluminum Target During Hypervelocity Impact
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Jianfei Yuan, Shuang Zhang, Lijiao Zhang, Jin Wu, Qingming Zhang, Yafei Han, Enling Tang, Mingyang Xu, Meng Wang, Shenghai Xiang, Liping He, Shuhua Liu, and Jin Xia
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010302 applied physics ,Nuclear and High Energy Physics ,Electron density ,Materials science ,02 engineering and technology ,Plasma ,021001 nanoscience & nanotechnology ,Condensed Matter Physics ,01 natural sciences ,law.invention ,symbols.namesake ,Physics::Plasma Physics ,law ,Ionization ,Physics::Space Physics ,0103 physical sciences ,Light-gas gun ,symbols ,Hypervelocity ,Electron temperature ,Langmuir probe ,Plasma diagnostics ,Atomic physics ,0210 nano-technology - Abstract
The theories of impact dynamics and adiabatic temperature change were adopted to investigate the ionization degree of the plasma generated by the 2A12 aluminum target during 2A12 aluminum projectile hypervelocity impact, and the radiant temperature was also estimated during hypervelocity impact. A two-stage light gas gun combined with the plasma characteristic parameters measured by a triple Langmuir probe was applied, and then the fitting relationship between the plasma ionization degree and the theoretical impact temperature as well as the fitting relationship between the maximum electron density and impact velocity were obtained with the aid of the theoretical derivation of the plasma ionization degree and the electron temperature and electron density extracted from experiments.
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- 2016
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123. Discharges of plasma induced by hypervelocity impact on the solar array with different substrate structures1
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Qingming Zhang, Enling Tang, Yafei Han, Hongliang Wang, Jin Xia, Zheng Li, Liping He, Shuhua Liu, Shenghai Xiang, Mingyang Xu, and Meng Wang
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010302 applied physics ,Materials science ,business.industry ,Mechanical Engineering ,Photovoltaic system ,Substrate (printing) ,Plasma ,Condensed Matter Physics ,01 natural sciences ,010305 fluids & plasmas ,Electronic, Optical and Magnetic Materials ,Astrobiology ,Mechanics of Materials ,0103 physical sciences ,Hypervelocity ,Optoelectronics ,Electrical and Electronic Engineering ,business - Published
- 2016
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124. Experimental study on plasma discharge induced by high-velocity impact solar array associated with projectile incidence angles
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Meng Wang, Enling Tang, Shuang Zhang, Hongliang Wang, Lijiao Zhang, Jin Xia, Shenghai Xiang, Zheng Li, Jianfei Yuan, Liping He, Shuhua Liu, and Mingyang Xu
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010302 applied physics ,Materials science ,Projectile ,business.industry ,Mechanical Engineering ,High velocity ,Photovoltaic system ,Plasma ,Condensed Matter Physics ,01 natural sciences ,010305 fluids & plasmas ,Electronic, Optical and Magnetic Materials ,Optics ,Mechanics of Materials ,0103 physical sciences ,Electrical and Electronic Engineering ,business ,Incidence (geometry) - Published
- 2016
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125. Damage Characteristics of the Logical Chip Module Due to Plasma Created by Hypervelocity Impacts
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Enling Tang, Jin Wu, Meng Wang, Lijiao Zhang, Shenghai Xiang, Jin Xia, Shuhua Liu, Liping He, Yafei Han, Mingyang Xu, Shuang Zhang, and Jianfei Yuan
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Physics ,020301 aerospace & aeronautics ,Spacecraft ,business.industry ,Acoustics ,System of measurement ,02 engineering and technology ,Condensed Matter Physics ,Chip ,01 natural sciences ,010305 fluids & plasmas ,law.invention ,Azimuth ,symbols.namesake ,0203 mechanical engineering ,law ,0103 physical sciences ,Light-gas gun ,Hypervelocity ,symbols ,Langmuir probe ,Plasma diagnostics ,business - Abstract
To researching the damage characteristics of typical logical chip modules in spacecraft due to plasma generated by hypervelocity impacts, we have established a triple Langmuir probe diagnostic system and a logical chips measurement system, which were used to diagnose plasma characteristic parameters and the logical chip module's logical state changes due to the plasma created by a 7075 aluminum projectile hypervelocity impact on the 2A12 aluminum target. Three sets of experiments were performed with the collision speeds of 2.85 km/s, 3.1 km/s and 2.20 km/s, at the same incident angles of 30 degrees and logical chip module's positions by using a two-stage light gas gun loading system, a plasma characteristic parameters diagnostic system and a logical chip module's logical state measurement system, respectively. Electron temperature and density were measured at given position and azimuth, and damage estimation was performed for the logical chip module by using the data acquisition system. Experimental results showed that temporary damage could be induced on logical chip modules in spacecraft by plasma generated by hypervelocity impacts under the given experimental conditions and the sensors' position and azimuth.
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- 2016
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126. A novel esterase LanE from Edaphocola flava HME-24 and the enantioselective degradation mechanism of herbicide lactofen
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Qi-feng Chen, Yun Xiang, Na Shang, Mingyang Xu, Xing Huang, and Ting Hu
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Stereochemistry ,Health, Toxicology and Mutagenesis ,0211 other engineering and technologies ,02 engineering and technology ,010501 environmental sciences ,Acifluorfen ,01 natural sciences ,Esterase ,chemistry.chemical_compound ,Hydrolysis ,Halogenated Diphenyl Ethers ,Pesticides ,Ecosystem ,0105 earth and related environmental sciences ,chemistry.chemical_classification ,021110 strategic, defence & security studies ,Strain (chemistry) ,biology ,Bacteroidetes ,Herbicides ,Esterases ,Public Health, Environmental and Occupational Health ,Stereoisomerism ,General Medicine ,biology.organism_classification ,Pollution ,Amino acid ,Molecular Docking Simulation ,Biodegradation, Environmental ,chemistry ,Nitrobenzoates ,Thermotoga maritima ,Enantiomer ,Lactofen - Abstract
Lactofen is a chiral herbicide and widely used against broadleaf weeds in agriculture. As a pesticide, it is directly released to the environment, and easily caused contamination in soil and aquatic ecosystem. The enantioselective degradation of lactofen in the environment has been reported, but the molecular biological mechanism of this phenomenon is still unclear. In this study, strain Edaphocola flava HME-24 could degrade 96.7% of 50 mg L−1 lactofen within 72 h. Lactofen was initially hydrolyzed to desethyl lactofen and subsequently acifluorfen by strain HME-24. A novel gene lanE, involved in lactofen transformation, was obtained from Edaphocola flava HME-24. Gene lanE encoded a protein of 471 amino acids that contained the conserved GXSXG esterase motif and clustered into esterase subfamily V. LanE shared the highest identity with esterase EstD (Q9WYH1) from Thermotoga maritima MSB8 (29.14%). This esterase was also able to transform p-nitrophenyl esters (C4–C8), and the activity decreased when the carbon chain length increased. LanE showed enantioselectivity during the degradation of lactofen, diclofop-methyl, and quizalofop-ethyl, with a higher degradation efficiency of (S)-enantiomers than (R)-enantiomers. The three-dimensional structure of LanE was simulated, and molecular docking revealed that when the (S)-enantiomers of lactofen occupied the active sites, the distance between the ligand molecule and the coordination atom was shorter than that when the (R)-enantiomers occupied the active sites, which facilitated the formation of the transition state complex. The results in this study enhanced our understanding of the preferential catabolism of the (S)-enantiomers of lactofen on the molecular level and could illustrate the reported enantioselective degradation of lactofen in the environment.
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- 2020
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127. Microjet formation from the grooved surface of aluminum under shock waves with different pulse durations
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Weidong Song, Jian-Li Shao, Cheng Wang, and Mingyang Xu
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Shock wave ,Surface (mathematics) ,Materials science ,chemistry.chemical_element ,Condensed Matter Physics ,Computer Science Applications ,Pulse (physics) ,Smoothed-particle hydrodynamics ,chemistry ,Mechanics of Materials ,Aluminium ,Modeling and Simulation ,General Materials Science ,Composite material ,Groove (engineering) - Published
- 2020
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128. Using depression deposits to reconstruct human impact on sediment yields from a small karst catchment over the past 600 years
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Zengli Pei, Peng Cheng, Xinbao Zhang, Xue Lu, Yi Long, Mingyang Xu, Yunqi Zhang, Haiquan Yang, and Zhehong Wu
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geography ,education.field_of_study ,geography.geographical_feature_category ,Environmental change ,Population ,Drainage basin ,Soil Science ,Sediment ,Context (language use) ,04 agricultural and veterinary sciences ,010501 environmental sciences ,Sedimentation ,Karst ,01 natural sciences ,Deforestation ,040103 agronomy & agriculture ,0401 agriculture, forestry, and fisheries ,Environmental science ,Physical geography ,education ,0105 earth and related environmental sciences - Abstract
Assessment of long-term human impact on sediment yields from karst settings can improve our understanding of the pattern of soil erosion causing rocky desertification in the historical context of environmental change influenced by human activity. Few previous investigations have estimated this impact over time-scales longer than 50 years. This study used dated depression deposits to reconstruct human impact on sediment yields from a small karst catchment in the Three Gorges Reservoir Region, China, over the past 600 years. 137Cs, 210Pbex, and 14C techniques were used to determine short-term (~50 yr), medium-term (~100 yr), and long-term (~600 yr) sedimentation in the karst depression, respectively. Sedimentation rates and specific sediment yields in the catchment during six distinct stages (1351–1462, 1463–1701, 1702–1809, 1810–1916, 1917–1962, and 1963–2017) were determined from core samples. The results indicate that soil loss during the period 1351–1962 was more intensive than that since 1963, which reveals changing sediment yields impacted by human activity over the past 600 years. The high values during the three stages before 1810 can be attributed to the impacts of large-scale migration of people from Huguang to Sichuan during the Ming and Qing dynasties; the higher values during 1810–1916 might reflect increasing disturbance related to rapid population expansion; the highest values (1917–1962) were caused by large-scale deforestation in 1958 and a consistently increasing population; and low values since 1963 reflect constraints on the supply of sediment source materials. These results suggest that rocky desertification might be a long-term land-surface process induced by human activity over timescales of >100 years rather than a short-term modern process occurring over a number of decades. This is the first attempt to examine the long-term history of human impact on sediment yields from a karst catchment using depression deposits. This work improves our understanding of the influence of human activities on soil loss at a depression-catchment scale, and of the evolution and dynamics of rocky desertification in karst areas.
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- 2020
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129. An Intelligent and Hybrid Weighted Fuzzy Time Series Model Based on Empirical Mode Decomposition for Financial Markets Forecasting
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Paul Jones, Haoqi Ni, Junyi He, Mingyang Xu, Nagiza F. Samatova, and Ruixin Yang
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0209 industrial biotechnology ,Computer science ,Financial market ,02 engineering and technology ,computer.software_genre ,Stock market index ,Fuzzy logic ,Hilbert–Huang transform ,Nonlinear system ,020901 industrial engineering & automation ,0202 electrical engineering, electronic engineering, information engineering ,020201 artificial intelligence & image processing ,Data mining ,Volatility (finance) ,Time series ,computer ,Human learning - Abstract
Given the potentially high impact of accurate financial market forecasting, there has been considerable research on time series analysis for financial markets. We present a new Intelligent Hybrid Weighted Fuzzy (IHWF) time series model to improve forecasting accuracy in financial markets, which are complex nonlinear time-sensitive systems, influenced by many factors. The IHWF model uniquely combines Empirical Mode Decomposition (EMD) with a novel weighted fuzzy time series method. The model is enhanced by an Adaptive Sine-Cosine Human Learning Optimization (ASCHLO) algorithm to help find optimal parameters that further improve forecasting performance. EMD is a time series processing technique to extract the possible modes of various kinds of institutional and individual investors and traders, embedded in a given time series. Subsequently, the proposed weighted fuzzy time series method with chronological order based frequency and Neighborhood Volatility Direction (NVD) is analyzed and integrated with ASCHLO to determine the effective universe discourse, intervals and weights. In order to evaluate the performance of proposed model, we evaluate actual trading data of Taiwan Capitalization Weighted Stock Index (TAIEX) from 1990 to 2004 and the findings are compared with other well-known forecasting models. The results show that the proposed method outperforms the listing models in terms of accuracy.
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- 2018
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130. Mining Aspect-Specific Opinions from Online Reviews Using a Latent Embedding Structured Topic Model
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Mingyang Xu, Paul Jones, Ruixin Yang, and Nagiza F. Samatova
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Topic model ,Computer science ,business.industry ,Sentiment analysis ,02 engineering and technology ,Coherence (statistics) ,computer.software_genre ,020204 information systems ,0202 electrical engineering, electronic engineering, information engineering ,Embedding ,020201 artificial intelligence & image processing ,Artificial intelligence ,business ,computer ,Word (computer architecture) ,Natural language processing - Abstract
Online reviews often contain user’s specific opinions on aspects (features) of items. These opinions are very useful to merchants and customers, but manually extracting them is time-consuming. Several topic models have been proposed to simultaneously extract item aspects and user’s opinions on the aspects, as well as to detect sentiment associated with the opinions. However, existing models tend to find poor aspect-opinion associations when limited examples of the required word co-occurrences are available in corpus. These models often also assign incorrect sentiment to words. In this paper, we propose a Latent embedding structured Opinion mining Topic model, called the LOT, which can simultaneously discover relevant aspect-level specific opinions from small or large numbers of reviews and to assign accurate sentiment to words. Experimental results for topic coherence, document sentiment classification, and a human evaluation all show that our proposed model achieves significant improvements over several state-of-the-art baselines.
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- 2018
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131. Optimization of temperature field of tobacco heat shrink machine
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Hai Yang, Dong Sun, Xudong Yang, and Mingyang Xu
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Materials science ,Field (physics) ,Mechanics - Published
- 2018
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132. Simulation Analysis of Cracked Steel Plate Bonded with Composite Patches
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Mo, Hu, primary, Hao, Feng, additional, Chenbo, Yin, additional, and Mingyang, Xu, additional
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- 2019
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133. Facile synthesis of graphene-like Co3S4 nanosheet/Ag2S nanocomposite with enhanced performance in visible-light photocatalysis
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Chengfeng Zhu, Jiming Song, Mingyang Xu, Jinjing Huang, Changle Chen, Shengyi Zhang, Chang-Jie Mao, and Helin Niu
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Nanocomposite ,Materials science ,Graphene ,General Physics and Astronomy ,Nanoparticle ,Nanotechnology ,Surfaces and Interfaces ,General Chemistry ,Condensed Matter Physics ,Surfaces, Coatings and Films ,Nanomaterials ,law.invention ,chemistry.chemical_compound ,Chemical engineering ,chemistry ,law ,Photocatalysis ,Methyl orange ,Visible spectrum ,Nanosheet - Abstract
Visible light photocatalysts have stimulated great research efforts. In this contribution, graphene-like Co 3 S 4 nanosheet/Ag 2 S nanocomposite was prepared using a simple method, and characterized by transmission electron microscopy, X-ray diffraction, and UV–Vis DRS, etc. The photocatalytic properties of the nanocomposite was evaluated by the photocatalytic degradation of Methylene blue (MB) and Methyl orange (MO) under visible light irradiation. The nanocomposite photocatalyst displays excellent stability and photocatalytic activity compared with pure Co 3 S 4 nanosheet or Ag 2 S nanoparticles. The superior photocatalytic properties were attributed to its unique structures, which could promote efficiently electron/hole separation and transportation.
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- 2015
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134. Spectral Analysis of the Light Flash Produced by a Natural Dolomite Plate Under Strong Shock
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Shuang Zhang, Yafei Han, Mingyang Xu, Jianfei Yuan, Di Wang, Jin Wu, Jin Xia, Meng Wang, Xiaohan Shi, Qingming Zhang, Lijiao Zhang, Shenghai Xiang, and Enling Tang
- Subjects
Projectile ,business.industry ,chemistry.chemical_element ,Condensed Matter Physics ,Electromagnetic radiation ,Computational physics ,law.invention ,Shock (mechanics) ,Optics ,chemistry ,Aluminium ,Shot (pellet) ,law ,Light-gas gun ,Arc flash ,business ,Radiant intensity - Abstract
In order to obtain the elemental compositions of the projectile and target materials during 2A12 aluminum projectile shot on a natural dolomite plate, three kinds of experiments have been conducted using a spectral acquirement system established on a two-stage light gas gun for impact velocities ranging from 2.20 km/s to 4.20 km/s, at the same projectile incidence angle of 30°. Experimental results show that the elemental compositions of the projectile and target materials in the strong shock experiments have a good agreement with the original elemental compositions of the projectile and target. In addition, the relations between spectral radiant intensity and elemental compositions of the projectile and target materials have been obtained for different impact velocities, in which the spectral radiant intensity of the main elements in the material increases with increasing impact velocity, and more elements appear with increasing impact velocity since more energy would result from a higher velocity impact.
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- 2015
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135. The mechanism for brassinosteroids suppressing climacteric fruit ripening.
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Yinglin Ji, Yi Qu, Zhongyu Jiang, Jijun Yan, Jinfang Chu, Mingyang Xu, Xin Su, Hui Yuan, and Aide Wang
- Published
- 2021
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136. Isolation, Characterization, and Pathogenicity of an Aeromonas veronii Strain Causing Disease in Rhinogobio ventralis
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Xingbing Wu, Baolin Cheng, Mingyang Xue, Nan Jiang, Xuemei Li, Xiaona Hu, Xiaoli Li, Tingbing Zhu, Yongjiu Zhu, and Yong Zhou
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Rhinogobio ventralis ,Aeromonas veronii ,16S rRNA sequence analysis ,intestinal microbiota ,antibiotic sensitivity testing ,Biology (General) ,QH301-705.5 ,Genetics ,QH426-470 - Abstract
Rhinogobio ventralis is a rare fish found in the Yangtze River in China and has significant ecological and economic value. In this study, a bacterial strain (RV-JZ01) was isolated from the livers of diseased R. ventralis. This isolate was identified as Aeromonas veronii based on its morphology, biochemical features and 16S rDNA phylogenetic analysis. The artificial infection of healthy R. ventralis (16 ± 2 cm) with RV-JZ01 resulted in the manifestation of clinical symptoms, in accordance with those of naturally infected fish. The 50% lethal dose (LD50) of RV-JZ01 for R. ventralis was 6.3 × 106 CFU/mL. Histopathological examination revealed various pathological changes in the diseased fish, including intestinal villus swelling and rupture, hepatocyte vacuolization, renal tubular cell nuclear enlargement and pyknosis, and myocardial fiber fracture and atrophy. RV-JZ01 infection significantly reduced the gut flora diversity of R. ventralis, with the relative abundances of Firmicutes and Fusobacteria increasing, and those of the Proteobacteria and Bacteroidetes decreasing. The abundance of Lactobacillus and Streptococcus dramatically increased, and the abundance of Clostridium and Escherichia reduced in the intestinal microbiota of R. ventralis infected with RV-JZ01. Antibiotic sensitivity testing revealed that RV-JZ01 was highly susceptible to 12 antimicrobials, including erythromycin, cefalexin, norfloxacin, furazolidone, sulfonamides, enrofloxacin, doxycycline, piperacillin, florfenicol, gentamicin, and lincomycin. These results contribute to the understanding of pathological alterations in R. ventralis following A. veronii infection, offering valuable data to support the implementation of disease treatment.
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- 2024
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137. β-Sitosterol Reduces the Content of Triglyceride and Cholesterol in a High-Fat Diet-Induced Non-Alcoholic Fatty Liver Disease Zebrafish (Danio rerio) Model
- Author
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Peng Zhang, Naicheng Liu, Mingyang Xue, Mengjie Zhang, Zidong Xiao, Chen Xu, Yuding Fan, Junqiang Qiu, Qinghua Zhang, and Yong Zhou
- Subjects
β-sitosterol ,non-alcoholic fatty liver disease model ,zebrafish ,high-fat diet ,blood fat untargeted lipidomics ,lipid metabolism ,Veterinary medicine ,SF600-1100 ,Zoology ,QL1-991 - Abstract
Objective: Non-alcoholic fatty liver disease (NAFLD) is strongly associated with hyperlipidemia, which is closely related to high levels of sugar and fat. β-sitosterol is a natural product with significant hypolipidemic and cholesterol-lowering effects. However, the underlying mechanism of its action on aquatic products is not completely understood. Methods: A high-fat diet (HFD)-induced NAFLD zebrafish model was successfully established, and the anti-hyperlipidemic effect and potential mechanism of β-sitosterol were studied using oil red O staining, filipin staining, and lipid metabolomics. Results: β-sitosterol significantly reduced the accumulation of triglyceride, glucose, and cholesterol in the zebrafish model. Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis showed that differential lipid molecules in β-sitosterol mainly regulated the lipid metabolism and signal transduction function of the zebrafish model. β-sitosterol mainly affected steroid biosynthesis and steroid hormone biosynthesis in the zebrafish model. Compared with the HFD group, the addition of 500 mg/100 g of β-sitosterol significantly inhibited the expression of Ppar-γ and Rxr-α in the zebrafish model by at least 50% and 25%, respectively. Conclusions: β-sitosterol can reduce lipid accumulation in the zebrafish model of NAFLD by regulating lipid metabolism and signal transduction and inhibiting adipogenesis and lipid storage.
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- 2024
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138. Chinese giant salamander Bcl-w: An inhibitory role in iridovirus-induced mitochondrial apoptosis and virus replication
- Author
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Yiqun Li, Mingyang Xue, Yanlin Dai, Yixing Xie, Ying Wei, Cheng Wang, Mingzhu Tian, Yuding Fan, Nan Jiang, Chen Xu, Wenzhi Liu, Yan Meng, and Yong Zhou
- Subjects
Bcl-w ,Chinese giant salamander ,Apoptosis ,Bak ,p53 ,Virus replication ,Microbiology ,QR1-502 ,Infectious and parasitic diseases ,RC109-216 - Abstract
B-cell lymphoma-2 (BCL-2) superfamily molecules play crucial roles in mitochondrial apoptosis induced by Chinese giant salamander iridovirus (GSIV). As an anti-apoptotic molecule in the BCL-2 family, the molecular mechanism of Bcl-w during GSIV infection remains unknown. In this study, we characterized for the first time an amphibian Bcl-w from Chinese giant salamander Andrias davidianus (AdBcl-w), and its function and regulatory mechanism during GSIV infection were investigated. AdBcl-w possesses the conserved structural features of Bcl-w and shares 35–54% sequence identities with other Bcl-w. mRNA expression of AdBcl-w was most abundant in liver and muscle. The AdBcl-w mRNA expression was regulated during GSIV infection. Western blotting assays revealed that the level of Bcl-w protein was downregulated markedly as the infection progresses. Confocal microscopy showed that overexpressed AdBcl-w was translocated to the mitochondria after infection with GSIV. Flow cytometry analysis demonstrated that compared with control, the apoptotic progress in cells transfected with AdBcl-w was reduced while that in cells transfected with AdBcl-w siRNA was enhanced. The number of virus major capsid protein gene copies was lower and protein synthesis was reduced in AdBcl-w overexpressing cells. In addition, AdBcl-w could bind directly to the pro-apoptotic molecule AdBak, while this interaction was weakened with GSIV infection. Moreover, p53 level was reduced and the mRNA expression levels of crucial regulatory molecules in the p53 pathway were regulated in AdBcl-w overexpressing cells during GSIV infection. These results suggested that AdBcl-w inhibit GSIV replication by regulating the virus induced mitochondrial apoptosis.
- Published
- 2023
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139. Leveraging External Knowledge for Phrase-Based Topic Modeling
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Ruixin Yang, Mingyang Xu, Shijie Li, Stephen Ranshous, and Nagiza F. Samatova
- Subjects
Topic model ,Phrase ,business.industry ,Computer science ,InformationSystems_INFORMATIONSTORAGEANDRETRIEVAL ,Sentiment analysis ,02 engineering and technology ,Limiting ,computer.software_genre ,Set (abstract data type) ,020204 information systems ,0202 electrical engineering, electronic engineering, information engineering ,020201 artificial intelligence & image processing ,Artificial intelligence ,business ,Baseline (configuration management) ,computer ,Natural language processing - Abstract
Topic modeling has been widely used for extracting the major topics from a corpus. Each discovered topic contains a set of related individual words that describe the topic itself. The discovered topics summarize the major themes of the corpus. Recently, a few phrase-based topic models have been proposed, which simultaneously model phrases and topics. The topics discovered by these models consist of phrases besides individual words, as phrases are typically more meaningful. However, these models typically require large amounts of data to provide reliable statistics for phrase-based topic modeling, thus limiting their performance in scenarios with limited data. To address this limitation, we propose a knowledge-based topic model that incorporates two types of pre-identified external knowledge for topical phrase discovery: Phrase knowledge, and phrase correlation knowledge. Phrase knowledge guides the discovery of meaningful phrases by leveraging a set of pre-identified exemplary phrases; Phrase correlation knowledge guides the discovery of meaningful topics by exploiting a set of pre-identified pairs of related phrases. Experimental results show that our method outperforms the state-of-the-art baseline on both small and large datasets, extracting more meaningful phrases and coherent topics.
- Published
- 2017
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140. A Lifelong Learning Topic Model Structured Using Latent Embeddings
- Author
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Steve Harenberg, Ruixin Yang, Mingyang Xu, and Nagiza F. Samatova
- Subjects
Topic model ,Structure (mathematical logic) ,Exploit ,Computer science ,business.industry ,Lifelong learning ,02 engineering and technology ,Machine learning ,computer.software_genre ,020204 information systems ,0202 electrical engineering, electronic engineering, information engineering ,020201 artificial intelligence & image processing ,Artificial intelligence ,business ,computer ,Word (computer architecture) ,Natural language processing - Abstract
We propose a latent-embedding-structured lifelong learning topic model, called the LLT model, to discover coherent topics from a corpus. Specifically, we exploit latent word embeddings to structure our model and mine word correlation knowledge to assist in topic modeling. During each learning iteration, our model learns new word embeddings based on the topics generated in the previous learning iteration. Experimental results demonstrate that our LLT model is able to generate more coherent topics than state-of-the-art methods.
- Published
- 2017
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141. An Intelligent Weighted Fuzzy Time Series Model Based on a Sine-Cosine Adaptive Human Learning Optimization Algorithm and Its Application to Financial Markets Forecasting
- Author
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Nagiza F. Samatova, Ruixin Yang, Junyi He, Mingyang Xu, and Stephen Ranshous
- Subjects
0209 industrial biotechnology ,Mathematical optimization ,business.industry ,Financial market ,02 engineering and technology ,Machine learning ,computer.software_genre ,Stock market index ,Fuzzy logic ,Weighting ,Nonlinear system ,020901 industrial engineering & automation ,0202 electrical engineering, electronic engineering, information engineering ,Economics ,Trigonometric functions ,020201 artificial intelligence & image processing ,Artificial intelligence ,Time series ,business ,computer ,Stock (geology) - Abstract
Financial forecasting is an extremely challenging task given the complex, nonlinear nature of financial market systems. To overcome this challenge, we present an intelligent weighted fuzzy time series model for financial forecasting, which uses a sine-cosine adaptive human learning optimization (SCHLO) algorithm to search for the optimal parameters for forecasting. New weighted operators that consider frequency based chronological order and stock volume are analyzed, and SCHLO is integrated to determine the effective intervals and weighting factors. Furthermore, a novel short-term trend repair operation is developed to complement the final forecasting process. Finally, the proposed model is applied to four world major trading markets: the Dow Jones Index (DJI), the German Stock Index (DAX), the Japanese Stock Index (NIKKEI), and Taiwan Stock Index (TAIEX). Experimental results show that our model is consistently more accurate than the state-of-the-art baseline methods. The easy implementation and effective forecasting performance suggest our proposed model could be a favorable market application prospect.
- Published
- 2017
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142. Research on Client-side Defense Techniques of Cross-Site Scripting Attack
- Author
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Xuyang Wang and Mingyang Xu
- Subjects
World Wide Web ,Computer science ,Cross-site scripting ,Client-side ,Computer security ,computer.software_genre ,computer ,Javascript engine ,Browser security - Published
- 2017
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143. Scutellarin suppresses cartilage destruction in osteoarthritis mouse model by inhibiting the NF-κB and PI3K/AKT signaling pathways
- Author
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Yunpeng Zhao, Weiwei Li, Jiangfan Peng, Cheng Qiu, Jiayi Li, Yangtao Shangguan, Cuijuan Zhang, Yuanming Li, Tingguo Zhang, Feng Li, Ruize Qu, Mingyang Xu, and Wenhan Wang
- Subjects
Male ,0301 basic medicine ,Knee Joint ,Interleukin-1beta ,Immunology ,Anti-Inflammatory Agents ,Glucuronates ,Osteoarthritis ,Pharmacology ,Phosphatidylinositol 3-Kinases ,03 medical and health sciences ,chemistry.chemical_compound ,0302 clinical medicine ,Oral administration ,medicine ,Animals ,Immunology and Allergy ,Apigenin ,Protein kinase B ,PI3K/AKT/mTOR pathway ,Scutellarin ,Interleukin-6 ,NF-kappa B ,NF-κB ,medicine.disease ,Mice, Inbred C57BL ,Cartilage ,030104 developmental biology ,chemistry ,030220 oncology & carcinogenesis ,Tumor necrosis factor alpha ,Signal transduction ,Proto-Oncogene Proteins c-akt ,Signal Transduction - Abstract
Osteoarthritis (OA), a common and severe disease, is predominantly characterized by cartilage destruction, which results in the degeneration of joint surfaces. Nowadays, it is accepted that TNFα plays a critical role in OA. Scutellarin, the main bioactive flavonoid glycoside extracted form Erigeron breviscapus, has been reported to exert positive effects on anti-inflammatory reactions. However, the effect of scutellarin in OA is still unknown. In this study, we isolated and cultured primary murine chondrocytes, stimulating TNF-α, in the presence or absence of scutellarin treatment. We found that the inflammatory response stimulated by TNF-α was significantly inhibited by the addition of scutellarin. Moreover, we established OA mouse models induced by surgery. In this mouse model, both inflammatory reaction and cartilage degeneration were markedly inhibited by oral administration of scutellarin. Furthermore, the cellular mechanism underlying the protective effect of scutellarin in OA was clearly associated with the NF-κB and PI3K/AKT signaling pathways. Collectively, this study proposes scutellarin as a potential therapeutic to treat joint degenerative diseases, including OA.
- Published
- 2019
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144. Generation of electromagnetic effect and flash in hypervelocity impact of aluminum projectile on aluminum target
- Author
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Mingyang Xu and Weidong Song
- Subjects
Physics ,Flash (photography) ,Projectile ,Hypervelocity ,Black-body radiation ,Plasma ,Condensed Matter Physics ,Radiant intensity ,Intensity (heat transfer) ,Magnetic field ,Computational physics - Abstract
A 3D Smoothed Particle Hydrodynamics (SPH) code was developed to investigate the generation of electromagnetic effect and flash during hypervelocity impact of an aluminum projectile on an aluminum target. The Arrhenius equation and the Biot-Savart law were incorporated into the SPH code for calculating the plasma charge and the magnetic field intensity from the plasma. Planck's law for the blackbody spectral radiance was introduced into the SPH code to determine the flash radiation intensities of different characteristic wavelengths. By using the SPH code, the effect of impact velocities and angles on the magnetic field intensity and flash intensity was explored. The numerical results show that the magnetic field intensity and flash intensity increase significantly with the impact velocity. By decreasing the incident angle from 90° to 45°, the magnetic field intensity and flash intensity decrease. Finally, based on the numerical simulations, two semiempirical formulae were proposed to accurately describe the variation of magnetic field intensity and the evolution of the flash radiation intensity with the impact velocity and the impact angle.
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- 2019
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145. Wear resistance of a Ni-PTFE composite coating strengthened with nano-SiC particles
- Author
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Zongjun Tian, Mingyang Xu, Lida Shen, Kai Wang, Wei Jiang, and Zhanwen Wang
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Materials science ,Polymers and Plastics ,Scanning electron microscope ,Metals and Alloys ,Nanoparticle ,engineering.material ,Surfaces, Coatings and Films ,Electronic, Optical and Magnetic Materials ,Carbide ,Biomaterials ,Surface coating ,Coating ,Plating ,Nano ,engineering ,Composite material ,Electroplating - Published
- 2019
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- View/download PDF
146. Study on the properties of superhydrophobic nickel coating prepared by jet electrodeposition in a parallel magnetic field
- Author
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Mingyang Xu, Zongjun Tian, Mingbo Qiu, Lida Shen, and Wei Jiang
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Jet (fluid) ,Materials science ,Polymers and Plastics ,Metals and Alloys ,chemistry.chemical_element ,Surface energy ,Surfaces, Coatings and Films ,Electronic, Optical and Magnetic Materials ,Magnetic field ,Biomaterials ,Magnetization ,Surface coating ,Nickel ,Transition metal ,X-ray photoelectron spectroscopy ,chemistry ,Composite material - Published
- 2019
- Full Text
- View/download PDF
147. Infrared camouflage detection method for special vehicles based on improved SSD
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Mingyang Xu, Zhili Zhang, Xiaofeng Zhao, Jiaxing Yang, and Danpiao Wang
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Space and Planetary Science ,business.industry ,Infrared ,Computer science ,Camouflage ,Aerospace Engineering ,Computer vision ,Artificial intelligence ,Electrical and Electronic Engineering ,business ,Atomic and Molecular Physics, and Optics - Published
- 2019
- Full Text
- View/download PDF
148. Nonstructural protein NS17 of grass carp reovirus Honghu strain promotes virus infection by mediating cell-cell fusion and apoptosis
- Author
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Yanlin Dai, Yiqun Li, Xi Hu, Nan Jiang, Wenzhi Liu, Yan Meng, Yong Zhou, Chen Xu, Mingyang Xue, and Yuding Fan
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Grass carp reovirus Honghu strain ,GCRV-HH196 ,Aquareovirus ,NS17 ,Cell-cell fusion ,Apoptosis ,Microbiology ,QR1-502 ,Infectious and parasitic diseases ,RC109-216 - Abstract
Fusion-associated small transmembrane (FAST) proteins can promote cell fusion, alter membrane permeability and trigger apoptosis to promote virus proliferation in orthoreoviruses. However, it is unknown whether FAST proteins perform these functions in aquareoviruses (AqRVs). Non-structural protein 17 (NS17) carried by grass carp reovirus Honghu strain (GCRV-HH196) belongs to the FAST protein family, and we preliminarily explored its relevance to virus infection. NS17 has similar domains to FAST protein NS16 of GCRV-873, comprising a transmembrane domain, a polybasic cluster, a hydrophobic patch and a polyproline motif. It was observed in the cytoplasm and the cell membrane. Overexpression of NS17 enhanced the efficiency of cell-cell fusion induced by GCRV-HH196 and promoted virus replication. Overexpression of NS17 also led to DNA fragmentation and reactive oxygen species (ROS) accumulation, and it triggered apoptosis. The findings illuminate the functions of NS17 in GCRV infection, and provide a reference for the development of novel antiviral strategies.
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- 2023
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149. Pathological characteristics of Chinese soft-shelled turtle (Pelodiscus sinensis) with white abdominal disease
- Author
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Peng Zhang, Naicheng Liu, Mingyang Xue, Zidong Xiao, Mengjie Zhang, Yan Meng, Yuding Fan, Xiaowei Hu, Junqiang Qiu, Qinghua Zhang, and Yong Zhou
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Chinese soft-shelled turtle ,White abdominal disease ,Clinical symptoms ,Pathological characteristics ,Aquaculture. Fisheries. Angling ,SH1-691 - Abstract
White abdominal disease is one of the major diseases in Chinese soft-shelled turtle (Pelodiscus sinensis, SST) aquaculture. To clarify the pathological characteristics of white abdominal disease, 24 SSTs with typical white abdominal symptoms were collected from a farm in Hubei Province, China. First, the pathogens of the SSTs were detected, including viruses and bacteria. No virus was detected. A variety of bacteria have been isolated. The pathological characteristics of the diseased SSTs were then studied using hematological analysis, histopathological observation, intestinal microbial analysis, and immunity-related gene expression. Compared with the healthy SST, the number of red blood cells reduced from 1.2 ± 0.5 × 1013 /L to 1.5 ± 0.2 × 1012 /L in the diseased SSTs. Meanwhile, the number of white blood cells increased by nearly four-fold (from 1.8 ± 0.5 × 1010 /L to 7.1 ± 3.5 × 1010 /L). In the diseased SSTs, the liver displayed several abnormalities, such as hepatocyte vacuolation and changes in nonparenchymal tissue. Some glomeruli of the kidney showed necrosis and disintegration. Cavities and loose muscles were observed in the gastric muscle layer. The blurred boundary between the red pulp and white pulp of the spleen was accompanied by massive invasion of inflammatory cells. Significant differences were detected in the relative abundances of Proteobacteria (from 29% to 7%) and Fusobacteria (from 12% to 28%) between the diseased and healthy SSTs. Compared with those in the healthy SSTs, the gene expression levels of toll-like receptor 2(TLR), TLR3, and myeloid differentiation primary response 88 (MyD88) were increased, by more than 4-fold, 7-fold, and 5-fold, respectively (P
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- 2023
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150. Microhardness, wear, and corrosion resistance of Ni–SiC composite coating with magnetic-field-assisted jet electrodeposition
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Wei Jiang, Zongjun Tian, Mingbo Qiu, Lida Shen, and Mingyang Xu
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Materials science ,Polymers and Plastics ,Abrasive ,Metals and Alloys ,02 engineering and technology ,engineering.material ,010402 general chemistry ,021001 nanoscience & nanotechnology ,Microstructure ,01 natural sciences ,Indentation hardness ,Grain size ,0104 chemical sciences ,Surfaces, Coatings and Films ,Electronic, Optical and Magnetic Materials ,Corrosion ,Biomaterials ,Surface coating ,Coating ,Surface roughness ,engineering ,Composite material ,0210 nano-technology - Abstract
To improve the composite coating surface quality and performance, a magnetic-field-assisted method was used to manufacture Ni–SiC composite coating based on jet electrodeposition. The effect of different concentrations of SiC and the magnetic field on the surface morphology, microhardness, wear resistance, and corrosion resistance of the coating were investigated by (1) changing the content of nano-SiC particles in the bath, and (2) whether magnetic-field-assisted device was used. Results showed that adding nano-SiC can refine the coating grain size and reduce the surface roughness. The microhardness of the coating increased significantly from 442.65 HV to 514.03 HV for pure nickel coating, an increase of 16.12%; the microhardness increased to 542.76 HV with the introduction of a magnetic field. Magnetic field assistance can reduce cellular protrusions and improve flatness. The Ni–SiC coating wear resistance was strengthened with Magnetic-field-assisted, the wear mechanism changed from the fatigue wear to abrasive wear and adhesive wear. The corrosion resistance of Ni–SiC composite coating was also improved compared with pure Ni coating.
- Published
- 2018
- Full Text
- View/download PDF
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