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1,144 results on '"Mimura, K."'

116. Development of a Two-Phase Cold Plate

Author

MIYAZAKI, Y., FURUKAWA, M., ISHII, Y., SHIGEHARA, M., KOMORI, M., MIMURA, K., and OSHIMA, S.

Subjects
Physics::Fluid Dynamics
Abstract

A two-phase cold plate using evaporators of grooved double-pipe type has been tested in order to examine its heat transfer and hydrodynamic characteristics under practical operating conditions. Under uniform heat load, excellent temperature uniformity of the cold plate was obtained. Under uneven heat load, however, the temperature distributions were not uniform, high at an active area and low at an inactive area. It seems to be due to ineffective liquid flow through inactive pipes, which causes liquid shortage at active tubes and over-cooling by sub-cooled liquid at inactive tubes. Parallel operations with two cold plates were performed successfully demonstrating that the both temperatures were kept at the same level even under different heat loads. In a certain operating condition, individual flow rate of the two cold plates was observed to oscillate symmetrically to each other, while total flow rate was kept constant and no anomalous behavior on heat transfer was induced. Through the tests, a design approach for the cold plate from the viewpoint of a loop control technology was obtained., 資料番号: SA0033466000

Published
1990

121. P21.05: Immune tolerance induction using chorionic villus sampling (CVS) technique in rodent models

Author

Endo, M., primary, Takahashi, K., additional, Miyoshi, T., additional, Tsuritani, M., additional, Shimazu, Y., additional, Fujita, S., additional, Kakigano, A., additional, Taniguchi, Y., additional, Mimura, K., additional, Kanagawa, T., additional, Hosoda, H., additional, Kimura, T., additional, Tamai, K., additional, and Yoshimatsu, J., additional

Published
2014
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124. Anion-exchange separation of Zr from Hf using a multi-column method.

Author

Uchikoshi M., T.T. Chen honorary symposium on hydrometallurgy, electrometallurgy and materials characterisation Orlando, Florida 11-Mar-1215-Mar-12, Isshiki M., Mimura K., Uchikoshi M., T.T. Chen honorary symposium on hydrometallurgy, electrometallurgy and materials characterisation Orlando, Florida 11-Mar-1215-Mar-12, Isshiki M., and Mimura K.

Abstract

HfO2 is a potential replacement for SiO2 as a gate dielectric in ultra- large-scale integration (ULSI). Commercial Hf contains more than 2 wt% Zr and the Zr must be removed to obtain material of sufficient purity to be used in ULSI. A process was investigated for removing Zr using a strongly basic polystyrene-divinyl-benzene quaternary amine anion exchange resin. A solution was prepared containing HfCl4 and ZrCl4 in HCl with Hf(IV) and Zr(IV) concentrations of 10 000 and 100 mg/dm3. The effect of the flow rate of the solution on the Hf(IV) and Zr(IV) chromatograms and on the adsorption rates was studied using flow rates of 2 500, 1 500, 500 and 167 mm/h. A decrease in the flow rate resulted in a broadening of the elution curves for Hf(IV) and Zr(IV), in contrast to the behaviour of Co(II), Cu(II) and Fe(III) due to the difference in adsorption rates on the resin. For a single column a higher Zr elimination ratio was obtained at 20 degrees C in 9.5 M HCl as determined by the separation factor. A higher elimination ratio was achieved using multiple columns connected in series and the Zr(IV) content was reduced to 1/100 relative to that of the raw material., HfO2 is a potential replacement for SiO2 as a gate dielectric in ultra- large-scale integration (ULSI). Commercial Hf contains more than 2 wt% Zr and the Zr must be removed to obtain material of sufficient purity to be used in ULSI. A process was investigated for removing Zr using a strongly basic polystyrene-divinyl-benzene quaternary amine anion exchange resin. A solution was prepared containing HfCl4 and ZrCl4 in HCl with Hf(IV) and Zr(IV) concentrations of 10 000 and 100 mg/dm3. The effect of the flow rate of the solution on the Hf(IV) and Zr(IV) chromatograms and on the adsorption rates was studied using flow rates of 2 500, 1 500, 500 and 167 mm/h. A decrease in the flow rate resulted in a broadening of the elution curves for Hf(IV) and Zr(IV), in contrast to the behaviour of Co(II), Cu(II) and Fe(III) due to the difference in adsorption rates on the resin. For a single column a higher Zr elimination ratio was obtained at 20 degrees C in 9.5 M HCl as determined by the separation factor. A higher elimination ratio was achieved using multiple columns connected in series and the Zr(IV) content was reduced to 1/100 relative to that of the raw material.

Published
2012

126. Identification of novel clostridium perfringens type E strains that carry an iota toxin plasmid with a functional enterotoxin gene

Author

Miyamoto, K, Yumine, N, Mimura, K, Nagahama, M, Li, J, McClane, BA, Akimoto, S, Miyamoto, K, Yumine, N, Mimura, K, Nagahama, M, Li, J, McClane, BA, and Akimoto, S

Abstract

Clostridium perfringens enterotoxin (CPE) is a major virulence factor for human gastrointestinal diseases, such as food poisoning and antibiotic associated diarrhea. The CPE-encoding gene (cpe) can be chromosomal or plasmid-borne. Recent development of conventional PCR cpe-genotyping assays makes it possible to identify cpe location (chromosomal or plasmid) in type A isolates. Initial studies for developing cpe genotyping assays indicated that all cpe-positive strains isolated from sickened patients were typable by cpe-genotypes, but surveys of C. perfringens environmental strains or strains from feces of healthy people suggested that this assay might not be useful for some cpe-carrying type A isolates. In the current study, a pulsed-field gel electrophoresis Southern blot assay showed that four cpe-genotype untypable isolates carried their cpe gene on a plasmid of ~65 kb. Complete sequence analysis of the ~65 kb variant cpe-carrying plasmid revealed no intact IS elements and a disrupted cytosine methyltransferase (dcm) gene. More importantly, this plasmid contains a conjugative transfer region, a variant cpe gene and variant iota toxin genes. The toxin genes encoded by this plasmid are expressed based upon the results of RT-PCR assays. The ~65 kb plasmid is closely related to the pCPF4969 cpe plasmid of type A isolates. MLST analyses indicated these isolates belong to a unique cluster of C. perfringens. Overall, these isolates carrying a variant functional cpe gene and iota toxin genes represent unique type E strains. © 2011 Miyamoto et al.

Published
2011

131. Blood Glucose Dependence on Emotional Behaviors and Body Surface Temperatures in Common Marmoset's Socio-Psychological Learning with Peers - for 'Development of Human-Environment Interface by Sensing and Multivariate Analysis of Bio-Ecosystem' -

Author

Koshiba, M., primary, Seno, A., additional, Karino, G., additional, Shirakawa, Y., additional, Mimura, K., additional, Sagawa, T., additional, Tsugawa, W., additional, Sode, K., additional, and Nakamura, S., additional

Published
2013
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132. Interstitial muscle insulin and glucose levels in normal and insulin-resistant Zucker rats

Author

Per Björntorp, Agneta Holmäng, Mimura K, and Peter Lönnroth

Subjects
Blood Glucose, Male, Microdialysis, medicine.medical_specialty, medicine.medical_treatment, Endocrinology, Diabetes and Metabolism, Injections, Subcutaneous, Carbohydrate metabolism, In vivo, Internal medicine, medicine, Hyperinsulinemia, Internal Medicine, Animals, Insulin, Obesity, Infusions, Intravenous, Muscle, Skeletal, Pancreatic hormone, Chemistry, Skeletal muscle, Glucose clamp technique, medicine.disease, Rats, Rats, Zucker, Kinetics, Endocrinology, medicine.anatomical_structure, Glucose, Regional Blood Flow, Glucose Clamp Technique, Insulin Resistance, Extracellular Space, Muscle Contraction
Abstract

To study interstitial insulin and glucose concentrations, microdialysis was performed in the medial femoral muscles in normal SD rats as well as in insulin-resistant obese Zucker rats during a euglycemic insulin clamp. [14C]inulin was given (0.1 mCi/rat) as a constant subcutaneous infusion 24 h before the insulin clamp. Insulin infusion rates were 5-8 mU x kg(-1) x min(-1) (low rate) for 140 min and 10-20 mU x kg(-1) x min(-1) (high rate) for another 100 min. The relationship between insulin and [14C]inulin dialysate recoveries was evaluated in vivo and in vitro in plasma to calculate interstitial insulin concentration. Relative microdialysis recovery of interstitial insulin in vivo was 3.0 +/- 0.3% (mean +/- SE, n = 68). In normal SD rats, plasma and interstitial insulin concentrations were identical when plasma insulin wasor =250 mU/ml, whereas interstitial insulin was lower when plasma insulin wasor =350 mU/ml. Half-maximal glucose infusion rate was achieved in the presence of plasma and interstitial insulin concentrations of approximately 140 mU/ml, whereas maximal glucose disposal was seen at interstitial insulin concentrations of approximately 325 mU/ml, corresponding to approximately 500 mU/ml in plasma. In electrically stimulated and contracting (1 Hz) normal muscle with markedly increased blood flow, the dialysate insulin concentration was significantly higher at high rates, but not at low rates, of insulin infusion. In insulin-resistant obese Zucker rats, the interstitial insulin concentration was similar to that in plasma, even at pharmacological concentrations. The glucose infusion rate was significantly lower in the obese Zucker rats at both insulin infusion rates than in the lean animals. The glucose content in dialysates from skeletal muscle was equal in both obese and lean rats during the low insulin infusion rate. During the high insulin infusion rate, dialysate glucose concentrations decreased significantly in both groups but were significantly higher in the obese Zucker rats. The data suggest that transport of insulin and glucose diffusion across the capillary wall are rate limiting for insulin as well as for glucose metabolism in muscle in normal rats. This does not appear to be the case in the insulin-resistant obese Zucker rats, where the reduced insulin responsiveness in muscle is due to muscular cellular defects rather than an inhibited transcapillary delivery of insulin.

Published
1997

136. X-dependent electronic structure of YbXCu4 (X=Cd, In, Sn) investigated by hard X-ray photoemission spectroscopy

Author

Utsumi, Y., primary, Sato, H., additional, Tobimatsu, K., additional, Maso, H., additional, Hiraoka, K., additional, Kojima, K., additional, Mimura, K., additional, Ueda, S., additional, Yamashita, Y., additional, Yoshikawa, H., additional, Kobayashi, K., additional, Shimada, K., additional, Namatame, H., additional, and Taniguchi, M., additional

Published
2011
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144. Visualization of a common structure of social behavior development in domestic chick and common marmoset

Author

Koshiba, M., primary, Suzuki, M., additional, Yamazaki, K., additional, Seno, A., additional, Okuya, M., additional, Mochizuki, D., additional, Sugiura, Y., additional, Shimizu, K., additional, Shirakawa, Y., additional, Mimura, K., additional, Aoki, I., additional, Kanno, I., additional, Honda, Y., additional, Tanaka, I., additional, Kodama, T., additional, Tokuno, H., additional, Usui, S., additional, and Nakamura, S., additional

Published
2010
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