101. Cryobiopsy - the utility in diagnostic bronchoscopy for ground-glass nodules
- Author
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Yuji Matsumoto, Yuichiro Ohe, Toshiyuki Nakai, Takaaki Tsuchida, Midori Tanaka, and Tomoki Nishida
- Subjects
medicine.medical_specialty ,medicine.diagnostic_test ,business.industry ,Forceps ,Interstitial lung disease ,Diagnostic Bronchoscopy ,medicine.disease ,Bronchoscopy ,medicine ,Fluoroscopy ,Sampling (medicine) ,Radiology ,business ,Forceps biopsy - Abstract
Diagnostic yield of bronchoscopy for peripheral pulmonary lesions has improved since the application of R-EBUS. R-EBUS enables us to confirm not only solid nodules but also ground-glass nodules (GGNs). However, diagnostic bronchoscopy for GGNs still has been challenging because of their subtle pathologic changes. Recently, cryobiopsy has made a great impact for the diagnosis of interstitial lung disease. We tried to apply cryobiopsy for GGNs, and researched the utility. Fifteen outpatients who underwent diagnostic bronchoscopy for GGNs at our hospital from June to September 2017 were enrolled. All procedures were performed using R-EBUS, virtual bronchoscopy, and X-ray fluoroscopy guidance under local anesthesia. After usual sampling (forceps, brush, or aspiration needle), cryobiopsy was added. The diagnostic value and the safety of cryobiopsy were reviewed. The median (range) size of total and solid part were 23.7 (14.4-35.3) and 12.5 (0-24.4) mm. Six nodules located in upper lobe, 11 nodules located at peripheral 1/3, and 6 nodules showed negative bronchus sign. We performed 67 times forceps biopsy and 17 times cryobiopsy. The median (range) area of specimens were significantly larger in cryobiopsy (12.6 [1.26-27.0] vs. 1.77 [0.116-5.88] mm2, p Cryobiopsy enabled us to obtain specimens with better quantity and quality. We could diagnose GGNs more precisely using cryobiopsy under controllable complications.
- Published
- 2018