91,460 results on '"Matthew, S."'
Search Results
102. The brief mind wandering three-factor scale (BMW-3)
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Schubert, Anna-Lena, Frischkorn, Gidon T., Sadus, Kathrin, Welhaf, Matthew S., Kane, Michael J., and Rummel, Jan
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- 2024
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103. Emigration of Juvenile Tarpon Megalops atlanticus from Ephemerally Connected Coastal Ponds
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Bunting, Matthew S., Stevens, Philip W., Blewett, David A., Tuckett, Quenton M., Hill, Jeffrey E., Poulakis, Gregg R., Shea, Colin P., and Saari, Courtney R.
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- 2024
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104. Genome-wide analysis of hepatic DNA methylation reveals impact of epigenetic aging on xenobiotic metabolism and transport genes in an aged mouse model
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Abudahab, Sara, Kronfol, Mohamad M., Dozmorov, Mikhail G., Campbell, Thomas, Jahr, Fay M., Nguyen, Jasmine, AlAzzeh, Ola, Al Saeedy, Dalia Y., Victor, Ashley, Lee, Sera, Malay, Shravani, Lapato, Dana M., Halquist, Matthew S., McRae, MaryPeace, Deshpande, Laxmikant S., Slattum, Patricia W., Price, Elvin T., and McClay, Joseph L.
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- 2024
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105. A Structured Knowledge Graph for a Geometric and Behavioral Digital Twin in the Context of Modal Testing
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Shen, Xiaoxue, Devaraja, Prajwal, Wagg, David, Bonney, Matthew S., Zimmerman, Kristin B., Series Editor, Platz, Roland, editor, Flynn, Garrison, editor, Neal, Kyle, editor, and Ouellette, Scott, editor
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- 2025
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106. Tribo-Dynamics Digital Twins (TDDTs): Prediction of Friction and Frequency Response Function (FRF) in a Dry Sliding Tribological Contact
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Taghizadeh, Saeid, Bonney, Matthew S., Wagg, David, Ghadbeigi, Hassan, Zimmerman, Kristin B., Series Editor, Platz, Roland, editor, Flynn, Garrison, editor, Neal, Kyle, editor, and Ouellette, Scott, editor
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- 2025
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107. Modeling Bolted Joints in the S4 Beam at Various Preloads with Discrete Iwan Elements
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Gilbert, Suzanna, Wynn, Carson, Stoker, Cameron, Capito, Jacob, Clawson, Samuel, Allen, Matthew S., Zimmerman, Kristin B., Series Editor, D'Ambrogio, Walter, editor, Roettgen, Dan, editor, and van der Seijs, Maarten, editor
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- 2025
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108. Functional Analysis in Simulated Environments
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Paul, Claire Donehower, Walker, Jennifer, Thomas, Cathy, Taylor, Matthew S., Best, Jamie, Diaz, Morgan, Rose, Chad A., and Vasquez, Eleazar
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The need for highly effective and qualified special educators continues to be a national concern. One of the primary reasons why teachers leave the profession is a lack of effective behavior management skills. Learning how to assess challenging behavior and its causes through functional analysis is one method to enhance teacher skillset in this critical area. The purpose of this study was to investigate the use of a simulation environment to train pre-service and in-service general and special education teachers to conduct functional analysis procedures with fidelity and compare those results to traditional didactic instruction. The results of the study show that simulated rehearsal experiences can be as effective as traditional role play experiences in training teachers to implement functional analysis procedures and may have added benefits such as increased safety and access to immediate feedback and coaching.
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- 2023
109. Alternative Methods for Item Parameter Estimation: From CTT to IRT. Research Report. ETS RR-22-12
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Guo, Hongwen, Lu, Ru, Johnson, Matthew S., and McCaffrey, Dan F.
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It is desirable for an educational assessment to be constructed of items that can differentiate different performance levels of test takers, and thus it is important to estimate accurately the item discrimination parameters in either classical test theory or item response theory. It is particularly challenging to do so when the sample sizes are small. The current study reexamined the relationship between the biserial correlation coefficient and the discrimination parameter to investigate whether the biserial correlation coefficient estimator could be modified and whether biserial-based estimators could be used as alternate estimates of the item discrimination indices. Results show that the modified and alternative approaches work slightly better under certain circumstances (e.g., for small sample sizes or shorter tests), assuming normality of the latent ability distribution. Applications of these alternative estimators are presented in item scaling and weighted differential item functioning analyses. Recommendations and limitations are discussed for practical use of these proposed methods.
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- 2022
110. Economics of Electrowinning Iron from Ore for Green Steel Production
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Humbert, Matthew S., Brooks, Geoffrey A., Duffy, Alan R., Hargrave, Chad, and Rhamdhani, M. Akbar
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- 2024
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111. Individual differences in working memory capacity and temporal preparation: A secondary reanalysis
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Welhaf, Matthew S.
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- 2024
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112. Evoking natural thermal perceptions using a thin-film thermoelectric device with high cooling power density and speed
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Osborn, Luke E., Venkatasubramanian, Rama, Himmtann, Meiyong, Moran, Courtney W., Pierce, Jonathan M., Gajendiran, Priya, Wormley, Jared M., Ung, Richard J., Nguyen, Harrison H., Crego, Adam C. G., Fifer, Matthew S., and Armiger, Robert S.
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- 2024
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113. Analysis of Langevin Monte Carlo from Poincaré to Log-Sobolev
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Chewi, Sinho, Erdogdu, Murat A., Li, Mufan, Shen, Ruoqi, and Zhang, Matthew S.
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- 2024
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114. Systematic assessment of long-read RNA-seq methods for transcript identification and quantification
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Pardo-Palacios, Francisco J., Wang, Dingjie, Reese, Fairlie, Diekhans, Mark, Carbonell-Sala, Sílvia, Williams, Brian, Loveland, Jane E., De María, Maite, Adams, Matthew S., Balderrama-Gutierrez, Gabriela, Behera, Amit K., Gonzalez Martinez, Jose M., Hunt, Toby, Lagarde, Julien, Liang, Cindy E., Li, Haoran, Meade, Marcus Jerryd, Moraga Amador, David A., Prjibelski, Andrey D., Birol, Inanc, Bostan, Hamed, Brooks, Ashley M., Çelik, Muhammed Hasan, Chen, Ying, Du, Mei R. M., Felton, Colette, Göke, Jonathan, Hafezqorani, Saber, Herwig, Ralf, Kawaji, Hideya, Lee, Joseph, Li, Jian-Liang, Lienhard, Matthias, Mikheenko, Alla, Mulligan, Dennis, Nip, Ka Ming, Pertea, Mihaela, Ritchie, Matthew E., Sim, Andre D., Tang, Alison D., Wan, Yuk Kei, Wang, Changqing, Wong, Brandon Y., Yang, Chen, Barnes, If, Berry, Andrew E., Capella-Gutierrez, Salvador, Cousineau, Alyssa, Dhillon, Namrita, Fernandez-Gonzalez, Jose M., Ferrández-Peral, Luis, Garcia-Reyero, Natàlia, Götz, Stefan, Hernández-Ferrer, Carles, Kondratova, Liudmyla, Liu, Tianyuan, Martinez-Martin, Alessandra, Menor, Carlos, Mestre-Tomás, Jorge, Mudge, Jonathan M., Panayotova, Nedka G., Paniagua, Alejandro, Repchevsky, Dmitry, Ren, Xingjie, Rouchka, Eric, Saint-John, Brandon, Sapena, Enrique, Sheynkman, Leon, Smith, Melissa Laird, Suner, Marie-Marthe, Takahashi, Hazuki, Youngworth, Ingrid A., Carninci, Piero, Denslow, Nancy D., Guigó, Roderic, Hunter, Margaret E., Maehr, Rene, Shen, Yin, Tilgner, Hagen U., Wold, Barbara J., Vollmers, Christopher, Frankish, Adam, Au, Kin Fai, Sheynkman, Gloria M., Mortazavi, Ali, Conesa, Ana, and Brooks, Angela N.
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- 2024
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115. Positively framing mind wandering does not increase mind wandering in older adults
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Welhaf, Matthew S. and Bugg, Julie M.
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- 2024
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116. Bayesian analysis on missing visual information and object complexity on visual search for object orientation and object identity
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Nguyen, Rachel T. T. and Peterson, Matthew S.
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- 2024
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117. Parent and staff perceptions of racism in a single-center neonatal intensive care unit
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Karvonen, Kayla L., Smith, Olga, Chambers Butcher, Brittany D., Franck, Linda S., McKenzie-Sampson, Safyer, McLemore, Monica R., Pantell, Matthew S., and Rogers, Elizabeth E.
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- 2024
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118. Dynamic Transcriptional Programs During Single NK Cell Killing: Connecting Form to Function in Cellular Immunotherapy
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Decker, Joseph T., Hall, Matthew S., Nanua, Devak, Orbach, Sophia M., Roy, Jyotirmoy, Angadi, Amogh, Caton, Julianna, Hesse, Lauren, Jeruss, Jacqueline S., and Shea, Lonnie D.
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- 2024
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119. Synthesis of 13C-depleted organic matter from CO in a reducing early Martian atmosphere
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Ueno, Yuichiro, Schmidt, Johan A., Johnson, Matthew S., Zang, Xiaofeng, Gilbert, Alexis, Kurokawa, Hiroyuki, Usui, Tomohiro, and Aoki, Shohei
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- 2024
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120. Transkingdom Network Analysis (TkNA): a systems framework for inferring causal factors underlying host–microbiota and other multi-omic interactions
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Newman, Nolan K., Macovsky, Matthew S., Rodrigues, Richard R., Bruce, Amanda M., Pederson, Jacob W., Padiadpu, Jyothi, Shan, Jigui, Williams, Joshua, Patil, Sankalp S., Dzutsev, Amiran K., Shulzhenko, Natalia, Trinchieri, Giorgio, Brown, Kevin, and Morgun, Andrey
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- 2024
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121. Early PSA decline after starting second-generation hormone therapy in the post-docetaxel setting predicts cancer-specific survival in metastatic castrate-resistant prostate cancer
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Ahmed, Mohamed E., Lee, Matthew S., Mahmoud, Ahmed M., Joshi, Vidhu B., Gopalakrishna, Ajay, Bole, Raevti, Haloi, Rimki, Kendi, A. Tuba, Bold, Michael S., Bryce, Alan H., Karnes, Robert Jeffrey, Kwon, Eugene D., Childs, Daniel S., and Andrews, Jack R.
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- 2024
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122. Removing grass clippings reduces bermudagrass mite (Acari: Eriophyidae) infestation during turfgrass regrowth
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Brown, Matthew S. and Chong, Juang Horng
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- 2024
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123. Neuraxial clonidine is not associated with lower post-cesarean opioid consumption or pain scores in parturients on chronic buprenorphine therapy: a retrospective cohort study
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Taylor, Michael G., Bauchat, Jeanette R., Sorabella, Laura L., Wanderer, Jonathan P., Feng, Xiaoke, Shotwell, Matthew S., and Ende, Holly B.
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- 2024
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124. Radiologists predict differential resource utilization but not clinical outcome in emergency department patients imaged with ultrasound for right upper quadrant pain
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Gaur, Sonia, Troost, Jonathan P., Fung, Christopher M., Breeden, Joshua, Barkmeier, Daniel, Shankar, Prasad R., Khalatbari, Shokoufeh, and Davenport, Matthew S.
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- 2024
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125. Gold nanoshells for prostate cancer treatment: evidence for deposition in abdominal organs
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Gaur, Sonia, Stein, Erica B., Schneider, Daniel K., Masotti, Maria, Davenport, Matthew S., George, Arvin K., and Ellis, James H.
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- 2024
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126. Systematic review: emotion dysregulation and challenging behavior interventions for children and adolescents on the autism spectrum with graded key evidence-based strategy recommendations
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Nuske, Heather J., Young, Amanda V., Khan, Farzana Y., Palermo, Emma H., Ajanaku, Bukola, Pellecchia, Melanie, Vivanti, Giacomo, Mazefsky, Carla A., Brookman-Frazee, Lauren, McPartland, James C., Goodwin, Matthew S., and Mandell, David S.
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- 2024
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127. Euclid Preparation. XXXVII. Galaxy colour selections with Euclid and ground photometry for cluster weak-lensing analyses
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Euclid Collaboration, Lesci, G. F., Sereno, M., Radovich, M., Castignani, G., Bisigello, L., Marulli, F., Moscardini, L., Baumont, L., Covone, G., Farrens, S., Giocoli, C., Ingoglia, L., La Hera, S. Miranda, Vannier, M., Biviano, A., Maurogordato, S., Aghanim, N., Amara, A., Andreon, S., Auricchio, N., Baldi, M., Bardelli, S., Bender, R., Bodendorf, C., Bonino, D., Branchini, E., Brescia, M., Brinchmann, J., Camera, S., Capobianco, V., Carbone, C., Carretero, J., Casas, S., Castander, F. J., Castellano, M., Cavuoti, S., Cimatti, A., Congedo, G., Conselice, C. J., Conversi, L., Copin, Y., Corcione, L., Courbin, F., Courtois, H. M., Da Silva, A., Degaudenzi, H., Di Giorgio, A. M., Dinis, J., Dubath, F., Duncan, C. A. J., Dupac, X., Dusini, S., Farina, M., Ferriol, S., Fosalba, P., Fotopoulou, S., Frailis, M., Franceschi, E., Franzetti, P., Fumana, M., Galeotta, S., Garilli, B., Gillis, B., Grazian, A., Grupp, F., Haugan, S. V. H., Hook, I., Hormuth, F., Hornstrup, A., Hudelot, P., Jahnke, K., Kümmel, M., Kermiche, S., Kiessling, A., Kilbinger, M., Kubik, B., Kunz, M., Kurki-Suonio, H., Ligori, S., Lilje, P. B., Lindholm, V., Lloro, I., Maiorano, E., Mansutti, O., Marggraf, O., Markovic, K., Martinet, N., Massey, R., Medinaceli, E., Melchior, M., Mellier, Y., Meneghetti, M., Merlin, E., Meylan, G., Moresco, M., Munari, E., Nakajima, R., Niemi, S. -M., Padilla, C., Paltani, S., Pasian, F., Pedersen, K., Pettorino, V., Pires, S., Polenta, G., Poncet, M., Popa, L. A., Pozzetti, L., Raison, F., Rebolo, R., Renzi, A., Rhodes, J., Riccio, G., Romelli, E., Roncarelli, M., Rossetti, E., Saglia, R., Sapone, D., Sartoris, B., Schirmer, M., Schneider, P., Secroun, A., Seidel, G., Serrano, S., Sirignano, C., Sirri, G., Skottfelt, J., Stanco, L., Starck, J. -L., Tallada-Crespí, P., Taylor, A. N., Teplitz, H. I., Tereno, I., Toledo-Moreo, R., Torradeflot, F., Tutusaus, I., Valentijn, E. A., Valenziano, L., Vassallo, T., Veropalumbo, A., Wang, Y., Weller, J., Zacchei, A., Zamorani, G., Zoubian, J., Zucca, E., Bolzonella, M., Bozzo, E., Colodro-Conde, C., Di Ferdinando, D., Graciá-Carpio, J., Marcin, S., Mauri, N., Neissner, C., Nucita, A. A., Sakr, Z., Scottez, V., Tenti, M., Viel, M., Wiesmann, M., Akrami, Y., Anselmi, S., Baccigalupi, C., Ballardini, M., Borgani, S., Borlaff, A. S., Bruton, S., Burigana, C., Cabanac, R., Calabro, A., Cappi, A., Carvalho, C. S., Castro, T., Cañas-Herrera, G., Chambers, K. C., Cooray, A. R., Coupon, J., Cucciati, O., Davini, S., de la Torre, S., De Lucia, G., Desprez, G., Di Domizio, S., Dole, H., Díaz-Sánchez, A., Vigo, J. A. Escartin, Escoffier, S., Ferrero, I., Finelli, F., Gabarra, L., Ganga, K., García-Bellido, J., Giacomini, F., Gozaliasl, G., Gwyn, S., Hildebrandt, H., Huertas-Company, M., Muñoz, A. Jimenez, Kajava, J. J. E., Kansal, V., Kirkpatrick, C. C., Legrand, L., Loureiro, A., Macias-Perez, J., Magliocchetti, M., Mainetti, G., Maoli, R., Martinelli, M., Martins, C. J. A. P., Matthew, S., Maturi, M., Maurin, L., Metcalf, R. B., Migliaccio, M., Monaco, P., Morgante, G., Nadathur, S., Patrizii, L., Pezzotta, A., Porciani, C., Potter, D., Pöntinen, M., Reimberg, P., Rocci, P. -F., Sánchez, A. G., Schneider, A., Schultheis, M., Sefusatti, E., Simon, P., Mancini, A. Spurio, Stanford, S. A., Steinwagner, J., Testera, G., Teyssier, R., Toft, S., Tosi, S., Troja, A., Tucci, M., Valiviita, J., and Vergani, D.
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Astrophysics - Cosmology and Nongalactic Astrophysics ,Astrophysics - Astrophysics of Galaxies - Abstract
We derived galaxy colour selections from Euclid and ground-based photometry, aiming to accurately define background galaxy samples in cluster weak-lensing analyses. Given any set of photometric bands, we developed a method for the calibration of optimal galaxy colour selections that maximises the selection completeness, given a threshold on purity. We calibrated galaxy selections using simulated ground-based $griz$ and Euclid $Y_{\rm E}J_{\rm E}H_{\rm E}$ photometry. Both selections produce a purity higher than 97%. The $griz$ selection completeness ranges from 30% to 84% in the lens redshift range $z_{\rm l}\in[0.2,0.8]$. With the full $grizY_{\rm E}J_{\rm E}H_{\rm E}$ selection, the completeness improves by up to $25$ percentage points, and the $z_{\rm l}$ range extends up to $z_{\rm l}=1.5$. The calibrated colour selections are stable to changes in the sample limiting magnitudes and redshift, and the selection based on $griz$ bands provides excellent results on real external datasets. The $griz$ selection is also purer at high redshift and more complete at low redshift compared to colour selections found in the literature. We find excellent agreement in terms of purity and completeness between the analysis of an independent, simulated Euclid galaxy catalogue and our calibration sample, except for galaxies at high redshifts, for which we obtain up to 50 percent points higher completeness. The combination of colour and photo-$z$ selections applied to simulated Euclid data yields up to 95% completeness, while the purity decreases down to 92% at high $z_{\rm l}$. We show that the calibrated colour selections provide robust results even when observations from a single band are missing from the ground-based data. Finally, we show that colour selections do not disrupt the shear calibration for stage III surveys., Comment: 20 pages, 13 figures. Published by A&A
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- 2023
128. Resolution- and Stimulus-agnostic Super-Resolution of Ultra-High-Field Functional MRI: Application to Visual Studies
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Li, Hongwei Bran, Rosen, Matthew S., Nasr, Shahin, and Iglesias, Juan Eugenio
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Electrical Engineering and Systems Science - Image and Video Processing ,Computer Science - Computer Vision and Pattern Recognition - Abstract
High-resolution fMRI provides a window into the brain's mesoscale organization. Yet, higher spatial resolution increases scan times, to compensate for the low signal and contrast-to-noise ratio. This work introduces a deep learning-based 3D super-resolution (SR) method for fMRI. By incorporating a resolution-agnostic image augmentation framework, our method adapts to varying voxel sizes without retraining. We apply this innovative technique to localize fine-scale motion-selective sites in the early visual areas. Detection of these sites typically requires a resolution higher than 1 mm isotropic, whereas here, we visualize them based on lower resolution (2-3mm isotropic) fMRI data. Remarkably, the super-resolved fMRI is able to recover high-frequency detail of the interdigitated organization of these sites (relative to the color-selective sites), even with training data sourced from different subjects and experimental paradigms -- including non-visual resting-state fMRI, underscoring its robustness and versatility. Quantitative and qualitative results indicate that our method has the potential to enhance the spatial resolution of fMRI, leading to a drastic reduction in acquisition time., Comment: ISBI2024 final version
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- 2023
129. Euclid preparation. Modelling spectroscopic clustering on mildly nonlinear scales in beyond-$\Lambda$CDM models
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Euclid Collaboration, Bose, B., Carrilho, P., Marinucci, M., Moretti, C., Pietroni, M., Carella, E., Piga, L., Wright, B. S., Vernizzi, F., Carbone, C., Casas, S., D'Amico, G., Frusciante, N., Koyama, K., Pace, F., Pourtsidou, A., Baldi, M., de la Bella, L. F., Fiorini, B., Giocoli, C., Lombriser, L., Aghanim, N., Amara, A., Andreon, S., Auricchio, N., Bardelli, S., Bodendorf, C., Bonino, D., Branchini, E., Brescia, M., Brinchmann, J., Camera, S., Capobianco, V., Cardone, V. F., Carretero, J., Castellano, M., Cavuoti, S., Cimatti, A., Congedo, G., Conselice, C. J., Conversi, L., Copin, Y., Costille, A., Courbin, F., Courtois, H. M., Da Silva, A., Degaudenzi, H., Di Giorgio, A. M., Dubath, F., Duncan, C. A. J., Dupac, X., Dusini, S., Farina, M., Farrens, S., Ferriol, S., Fosalba, P., Frailis, M., Franceschi, E., Galeotta, S., Garilli, B., Gillis, B., Grazian, A., Grupp, F., Guzzo, L., Haugan, S. V. H., Hormuth, F., Hornstrup, A., Jahnke, K., Joachimi, B., Keihänen, E., Kermiche, S., Kiessling, A., Kilbinger, M., Kitching, T., Kunz, M., Kurki-Suonio, H., Ligori, S., Lilje, P. B., Lindholm, V., Lloro, I., Maino, D., Maiorano, E., Mansutti, O., Marggraf, O., Markovic, K., Martinet, N., Marulli, F., Massey, R., Medinaceli, E., Meneghetti, M., Meylan, G., Moresco, M., Moscardini, L., Munari, E., Niemi, S. -M., Padilla, C., Paltani, S., Pasian, F., Pedersen, K., Percival, W. J., Pettorino, V., Pires, S., Polenta, G., Poncet, M., Popa, L. A., Pozzetti, L., Raison, F., Renzi, A., Rhodes, J., Riccio, G., Romelli, E., Roncarelli, M., Saglia, R., Sapone, D., Sartoris, B., Schneider, P., Secroun, A., Seidel, G., Seiffert, M., Serrano, S., Sirignano, C., Sirri, G., Stanco, L., Starck, J. -L., Tallada-Crespí, P., Taylor, A. N., Tereno, I., Toledo-Moreo, R., Torradeflot, F., Tutusaus, I., Valentijn, E. A., Valenziano, L., Vassallo, T., Veropalumbo, A., Wang, Y., Weller, J., Zamorani, G., Zoubian, J., Zucca, E., Biviano, A., Bozzo, E., Burigana, C., Colodro-Conde, C., Di Ferdinando, D., Graciá-Carpio, J., Mauri, N., Neissner, C., Sakr, Z., Scottez, V., Tenti, M., Viel, M., Wiesmann, M., Akrami, Y., Allevato, V., Anselmi, S., Ballardini, M., Bernardeau, F., Borgani, S., Bruton, S., Cabanac, R., Cappi, A., Carvalho, C. S., Castignani, G., Castro, T., Cañas-Herrera, G., Chambers, K. C., Cooray, A. R., Coupon, J., Davini, S., de la Torre, S., De Lucia, G., Desprez, G., Di Domizio, S., Dole, H., Díaz-Sánchez, A., Vigo, J. A. Escartin, Escoffier, S., Ferreira, P. G., Ferrero, I., Finelli, F., Gabarra, L., Ganga, K., García-Bellido, J., Giacomini, F., Gozaliasl, G., Guinet, D., Hall, A., Joudaki, S., Kajava, J. J. E., Kansal, V., Karagiannis, D., Kirkpatrick, C. C., Legrand, L., Loureiro, A., Macias-Perez, J., Magliocchetti, M., Maoli, R., Martinelli, M., Martins, C. J. A. P., Matthew, S., Maturi, M., Maurin, L., Metcalf, R. B., Migliaccio, M., Monaco, P., Morgante, G., Nadathur, S., Walton, Nicholas A., Patrizii, L., Pezzotta, A., Popa, V., Porciani, C., Potter, D., Pöntinen, M., Reimberg, P., Rocci, P. -F., Sánchez, A. G., Schneider, A., Sefusatti, E., Sereno, M., Silvestri, A., Mancini, A. Spurio, Steinwagner, J., Testera, G., Teyssier, R., Toft, S., Tosi, S., Troja, A., Tucci, M., Valiviita, J., and Vergani, D.
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Astrophysics - Cosmology and Nongalactic Astrophysics - Abstract
We investigate the approximations needed to efficiently predict the large-scale clustering of matter and dark matter halos in beyond-$\Lambda$CDM scenarios. We examine the normal branch of the Dvali-Gabadadze-Porrati model, the Hu-Sawicki $f(R)$ model, a slowly evolving dark energy, an interacting dark energy model and massive neutrinos. For each, we test approximations for the perturbative kernel calculations, including the omission of screening terms and the use of perturbative kernels based on the Einstein-de Sitter universe; we explore different infrared-resummation schemes, tracer bias models and a linear treatment of massive neutrinos; we employ two models for redshift space distortions, the Taruya-Nishimishi-Saito prescription and the Effective Field Theory of Large-Scale Structure. This work further provides a preliminary validation of the codes being considered by Euclid for the spectroscopic clustering probe in beyond-$\Lambda$CDM scenarios. We calculate and compare the $\chi^2$ statistic to assess the different modelling choices. This is done by fitting the spectroscopic clustering predictions to measurements from numerical simulations and perturbation theory-based mock data. We compare the behaviour of this statistic in the beyond-$\Lambda$CDM cases, as a function of the maximum scale included in the fit, to the baseline $\Lambda$CDM case. We find that the Einstein-de Sitter approximation without screening is surprisingly accurate for all cases when comparing to the halo clustering monopole and quadrupole obtained from simulations. Our results suggest that the inclusion of multiple redshift bins, higher-order multipoles, higher-order clustering statistics (such as the bispectrum) and photometric probes such as weak lensing, will be essential to extract information on massive neutrinos, modified gravity and dark energy., Comment: 29 pages, 10 figures, 4 tables, 3 appendices. Journal accepted version
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- 2023
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130. Radio survey of the stellar population in the infrared dark cloud G14.225-0.506
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Díaz-Márquez, Elena, Grau, Roger, Busquet, Gemma, Girart, Josep Miquel, Sánchez-Monge, Álvaro, Palau, Aina, Povich, Matthew S., Añez-López, Nacho, Liu, Hauyu Baobab, Zhang, Qizhou, and Estalella, Robert
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Astrophysics - Astrophysics of Galaxies ,Astrophysics - Solar and Stellar Astrophysics - Abstract
The IRDC G14.225-0.506 is associated with a network of filaments, which result in two different dense hubs, as well as with several signposts of star formation activity. The aim of this work is to study the cm continuum emission to characterize the stellar population in G14.2. We performed deep (~1.5-3 microJy) radio continuum observations at 6 and 3.6 cm using the VLA in the A configuration (~0.3''). We have also made use of observations taken during different days to study the presence of variability at short timescales. We detected a total of 66 sources, 32 in the northern region G14.2-N and 34 in the southern region G14.2-S. Ten of the sources are found to be variable. Based on their spectral index, the emission in G14.2-N is mainly dominated by non-thermal sources while G14.2-S contains more thermal emitters. Approximately 75% of the sources present a counterpart at other wavelengths. In the inner 0.4~pc region around the center of each hub, the number of IR sources in G14.2-N is larger than in G14.2-S by a factor of 4. We also studied the relation between the radio luminosity and the bolometric luminosity, finding that the thermal emission of the studied sources is compatible with thermal radio jets. For our sources with X-ray counterparts, the non-thermal emitters follow a G\"udel-Benz relation with k = 0.03. We found similar levels of fragmentation between G14.2-N and G14.2-S, suggesting that both regions are most likely twin hubs. The non-thermal emission found in the less evolved objects suggests that G14.2-N may be composed of more massive YSOs as well as being in a more advanced evolutionary stage, consistent with the filament-halo gradient in age and mass from previous works. Our results confirm a wider evolutionary sequence starting in G14.2-S as the youngest part, followed by G14.2-N, and ending with the most evolved region M17., Comment: 28 pages, 22 figures. Accepted for publication in A&A
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- 2023
131. A Theory for Neutron Star and Black Hole Kicks and Induced Spins
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Burrows, Adam, Wang, Tianshu, Vartanyan, David, and Coleman, Matthew S. B.
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Astrophysics - High Energy Astrophysical Phenomena ,Astrophysics - Astrophysics of Galaxies ,Astrophysics - Solar and Stellar Astrophysics - Abstract
Using twenty long-term 3D core-collapse supernova simulations, we find that lower compactness progenitors that explode quasi-spherically due to the short delay to explosion experience smaller neutron star recoil kicks in the $\sim$100$-$200 km s$^{-1}$ range, while higher compactness progenitors that explode later and more aspherically leave neutron stars with kicks in the $\sim$300$-$1000 km s$^{-1}$ range. In addition, we find that these two classes are correlated with the gravitational mass of the neutron star. This correlation suggests that the survival of binary neutron star systems may in part be due to their lower kick speeds. We also find a correlation of the kick with both the mass dipole of the ejecta and the explosion energy. Furthermore, one channel of black hole birth leaves masses of $\sim$10 $M_{\odot}$, is not accompanied by a neutrino-driven explosion, and experiences small kicks. A second is through a vigorous explosion that leaves behind a black hole with a mass of $\sim$3.0 $M_{\odot}$ kicked to high speeds. We find that the induced spins of nascent neutron stars range from seconds to $\sim$10 milliseconds, {but do not yet see a significant spin/kick correlation for pulsars.} We suggest that if an initial spin biases the explosion direction, a spin/kick correlation {would be} a common byproduct of the neutrino mechanism of core-collapse supernovae. Finally, the induced spin in explosive black hole formation is likely large and in the collapsar range. This new 3D model suite provides a greatly expanded perspective and appears to explain some observed pulsar properties by default., Comment: 16 pages, 7 figures. Accepted to ApJ
- Published
- 2023
132. Euclid preparation. Spectroscopy of active galactic nuclei with NISP
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Euclid Collaboration, Lusso, E., Fotopoulou, S., Selwood, M., Allevato, V., Calderone, G., Mancini, C., Mignoli, M., Scodeggio, M., Bisigello, L., Feltre, A., Ricci, F., La Franca, F., Vergani, D., Gabarra, L., Brun, V. Le, Maiorano, E., Palazzi, E., Moresco, M., Zamorani, G., Cresci, G., Jahnke, K., Humphrey, A., Landt, H., Mannucci, F., Marconi, A., Pozzetti, L., Salucci, P., Salvato, M., Shankar, F., Spinoglio, L., Stern, D., Serjeant, S., Aghanim, N., Altieri, B., Amara, A., Andreon, S., Auphan, T., Auricchio, N., Baldi, M., Bardelli, S., Bender, R., Bonino, D., Branchini, E., Brescia, M., Brinchmann, J., Camera, S., Capobianco, V., Carbone, C., Carretero, J., Casas, S., Castellano, M., Cavuoti, S., Cimatti, A., Congedo, G., Conselice, C. J., Conversi, L., Copin, Y., Corcione, L., Courbin, F., Courtois, H. M., Dinis, J., Dubath, F., Duncan, C. A. J., Dupac, X., Dusini, S., Farina, M., Farrens, S., Ferriol, S., Fourmanoit, N., Frailis, M., Franceschi, E., Franzetti, P., Fumana, M., Galeotta, S., Garilli, B., Gillard, W., Gillis, B., Giocoli, C., Grazian, A., Grupp, F., Haugan, S. V. H., Holmes, W., Hook, I., Hormuth, F., Hornstrup, A., Kümmel, M., Keihänen, E., Kermiche, S., Kubik, B., Kunz, M., Kurki-Suonio, H., Ligori, S., Lilje, P. B., Lindholm, V., Lloro, I., Mansutti, O., Marggraf, O., Markovic, K., Martinet, N., Marulli, F., Massey, R., Medinaceli, E., Mei, S., Mellier, Y., Merlin, E., Meylan, G., Moscardini, L., Munari, E., Niemi, S. -M., Padilla, C., Paltani, S., Pasian, F., Pedersen, K., Percival, W. J., Pettorino, V., Polenta, G., Poncet, M., Popa, L. A., Raison, F., Rebolo, R., Renzi, A., Rhodes, J., Riccio, G., Romelli, E., Roncarelli, M., Rossetti, E., Saglia, R., Sapone, D., Sartoris, B., Schneider, P., Secroun, A., Seidel, G., Serrano, S., Sirignano, C., Sirri, G., Stanco, L., Surace, C., Tallada-Crespí, P., Taylor, A. N., Teplitz, H. I., Tereno, I., Toledo-Moreo, R., Torradeflot, F., Tutusaus, I., Valentijn, E. A., Valenziano, L., Vassallo, T., Veropalumbo, A., Vibert, D., Wang, Y., Weller, J., Zoubian, J., Zucca, E., Biviano, A., Bolzonella, M., Bozzo, E., Burigana, C., Colodro-Conde, C., Di Ferdinando, D., Graciá-Carpio, J., Mainetti, G., Mauri, N., Neissner, C., Sakr, Z., Scottez, V., Tenti, M., Viel, M., Wiesmann, M., Akrami, Y., Anselmi, S., Baccigalupi, C., Ballardini, M., Bethermin, M., Borgani, S., Borlaff, A. S., Bruton, S., Cabanac, R., Calabro, A., Cappi, A., Carvalho, C. S., Castignani, G., Castro, T., Cañas-Herrera, G., Chambers, K. C., Cooray, A. R., Coupon, J., Cucciati, O., Davini, S., De Lucia, G., Desprez, G., Di Domizio, S., Dole, H., Díaz-Sánchez, A., Vigo, J. A. Escartin, Escoffier, S., Ferrero, I., Ganga, K., García-Bellido, J., Giacomini, F., Gozaliasl, G., Guinet, D., Hall, A., Hildebrandt, H., Muñoz, A. Jiminez, Kajava, J. J. E., Kansal, V., Kirkpatrick, C. C., Legrand, L., Loureiro, A., Macias-Perez, J., Magliocchetti, M., Maoli, R., Martinelli, M., Martins, C. J. A. P., Matthew, S., Maturi, M., Maurin, L., Metcalf, R. B., Migliaccio, M., Monaco, P., Morgante, G., Nadathur, S., Patrizii, L., Pezzotta, A., Popa, V., Porciani, C., Potter, D., Pöntinen, M., Rocci, P. -F., Sánchez, A. G., Schneider, A., Sefusatti, E., Sereno, M., Shulevski, A., Simon, P., Mancini, A. Spurio, Stadel, J., Stanford, S. A., Steinwagner, J., Testera, G., Teyssier, R., Toft, S., Tosi, S., Troja, A., Tucci, M., Valieri, C., Valiviita, J., and Zinchenko, I. A.
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Astrophysics - Astrophysics of Galaxies - Abstract
The statistical distribution and evolution of key properties (e.g. accretion rate, mass, or spin) of active galactic nuclei (AGN), remain an open debate in astrophysics. The ESA Euclid space mission, launched on July 1st 2023, promises a breakthrough in this field. We create detailed mock catalogues of AGN spectra, from the rest-frame near-infrared down to the ultraviolet, including emission lines, to simulate what Euclid will observe for both obscured (type 2) and unobscured (type 1) AGN. We concentrate on the red grisms of the NISP instrument, which will be used for the wide-field survey, opening a new window for spectroscopic AGN studies in the near-infrared. We quantify the efficiency in the redshift determination as well as in retrieving the emission line flux of the H$\alpha$+[NII] complex as Euclid is mainly focused on this emission line as it is expected to be the brightest one in the probed redshift range. Spectroscopic redshifts are measured for 83% of the simulated AGN in the interval where the H$\alpha$+[NII] is visible (0.89
2x10^{-16}$ erg s$^{-1}$ cm$^{-2}$, encompassing the peak of AGN activity at $z\simeq 1-1.5$) within the spectral coverage of the red grism. Outside this redshift range, the measurement efficiency decreases significantly. Overall, a spectroscopic redshift is correctly determined for ~90% of type 2 AGN down to an emission line flux of $3x10^{-16}$ erg s$^{-1}$ cm$^{-2}$, and for type 1 AGN down to $8.5x10^{-16}$ erg s$^{-1}$ cm$^{-2}$. Recovered black hole mass values show a small offset with respect to the input values ~10%, but the agreement is good overall. With such a high spectroscopic coverage at z<2, we will be able to measure AGN demography, scaling relations, and clustering from the epoch of the peak of AGN activity down to the present-day Universe for hundreds of thousand AGN with homogeneous spectroscopic information., Comment: 29 pages, 23 figures. Submitted to A&A, revised version - Published
- 2023
133. Deterministic preparation of optical squeezed cat and Gottesman-Kitaev-Preskill states
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Winnel, Matthew S., Guanzon, Joshua J., Singh, Deepesh, and Ralph, Timothy C.
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Quantum Physics - Abstract
Large-amplitude squeezed cat and high-quality Gottesman-Kitaev-Preskill (GKP) states are powerful resources for quantum error correction. However, previous schemes in optics are limited to low success probabilities, small amplitudes, and low squeezing. We overcome these limitations and present scalable schemes in optics for the deterministic preparation of large-amplitude squeezed cat states using only Gaussian operations and photon-number measurements. These states can be bred to prepare high-quality approximate GKP states, showing that GKP error correction in optics is technically feasible in near-term experiments., Comment: 19 pages, 11 figures
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- 2023
134. Valley-hybridized gate-tunable 1D exciton confinement in MoSe2
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Heithoff, Maximilian, Moreno, Álvaro, Torre, Iacopo, Feuer, Matthew S. G., Purser, Carola M., Andolina, Gian Marcello, Calajo, Giuseppe, Watanabe, Kenji, Taniguchi, Takashi, Kara, Dhiren, Hays, Patrick, Tongay, Sefaattin, Falko, Vladimir, Chang, Darrick, Atatüre, Mete, Reserbat-Plantey, Antoine, and Koppens, Frank
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Condensed Matter - Mesoscale and Nanoscale Physics ,Condensed Matter - Quantum Gases - Abstract
Controlling excitons at the nanoscale in semiconductor materials represents a formidable challenge in the fields of quantum photonics and optoelectronics. Achieving this control holds great potential for unlocking strong exciton-exciton interaction regimes, enabling exciton-based logic operations, exploring exotic quantum phases of matter, facilitating deterministic positioning and tuning of quantum emitters, and designing advanced optoelectronic devices. Monolayers of transition metal dichalcogenides (TMDs) offer inherent two-dimensional confinement and possess significant binding energies, making them particularly promising candidates for achieving electric-field-based confinement of excitons without dissociation. While previous exciton engineering strategies have predominantly focused on local strain gradients, the recent emergence of electrically confined states in TMDs has paved the way for novel approaches. Exploiting the valley degree of freedom associated with these confined states further broadens the prospects for exciton engineering. Here, we show electric control of light polarization emitted from one-dimensional (1D) quantum confined states in MoSe2. By employing non-uniform in-plane electric fields, we demonstrate the in-situ tuning of the trapping potential and reveal how gate-tunable valley-hybridization gives rise to linearly polarized emission from these localized states. Remarkably, the polarization of the localized states can be entirely engineered through either the spatial geometry of the 1D confinement potential or the application of an out-of-plane magnetic field.
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- 2023
135. Euclid Preparation. TBD. Impact of magnification on spectroscopic galaxy clustering
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Euclid Collaboration, Jelic-Cizmek, G., Sorrenti, F., Lepori, F., Bonvin, C., Camera, S., Castander, F. J., Durrer, R., Fosalba, P., Kunz, M., Lombriser, L., Tutusaus, I., Viglione, C., Sakr, Z., Aghanim, N., Amara, A., Andreon, S., Baldi, M., Bardelli, S., Bodendorf, C., Bonino, D., Branchini, E., Brescia, M., Brinchmann, J., Capobianco, V., Carbone, C., Cardone, V. F., Carretero, J., Casas, S., Castellano, M., Cavuoti, S., Cimatti, A., Congedo, G., Conselice, C. J., Conversi, L., Copin, Y., Corcione, L., Courbin, F., Courtois, H. M., Cropper, M., Degaudenzi, H., Di Giorgio, A. M., Dinis, J., Dubath, F., Dupac, X., Dusini, S., Farina, M., Farrens, S., Ferriol, S., Frailis, M., Franceschi, E., Fumana, M., Galeotta, S., Garilli, B., Gillis, B., Giocoli, C., Grazian, A., Grupp, F., Haugan, S. V. H., Hoekstra, H., Holmes, W., Hormuth, F., Hornstrup, A., Jahnke, K., Keihänen, E., Kermiche, S., Kiessling, A., Kilbinger, M., Kubik, B., Kurki-Suonio, H., Lilje, P. B., Lindholm, V., Lloro, I., Mansutti, O., Marggraf, O., Markovic, K., Martinet, N., Marulli, F., Massey, R., Medinaceli, E., Mei, S., Meneghetti, M., Merlin, E., Meylan, G., Moscardini, L., Munari, E., Niemi, S. -M., Padilla, C., Paltani, S., Pasian, F., Pedersen, K., Percival, W. J., Pettorino, V., Polenta, G., Poncet, M., Popa, L. A., Raison, F., Rebolo, R., Renzi, A., Rhodes, J., Riccio, G., Romelli, E., Roncarelli, M., Rossetti, E., Saglia, R., Sapone, D., Sartoris, B., Schneider, P., Schrabback, T., Secroun, A., Seidel, G., Serrano, S., Sirignano, C., Sirri, G., Stanco, L., Starck, J. -L., Surace, C., Tallada-Crespí, P., Tavagnacco, D., Taylor, A. N., Tereno, I., Toledo-Moreo, R., Torradeflot, F., Valentijn, E. A., Valenziano, L., Vassallo, T., Veropalumbo, A., Wang, Y., Weller, J., Zamorani, G., Zoubian, J., Zucca, E., Biviano, A., Boucaud, A., Bozzo, E., Colodro-Conde, C., Di Ferdinando, D., Graciá-Carpio, J., Liebing, P., Mauri, N., Neissner, C., Scottez, V., Tenti, M., Viel, M., Wiesmann, M., Akrami, Y., Allevato, V., Anselmi, S., Baccigalupi, C., Balaguera-Antolínez, A., Ballardini, M., Bruton, S., Burigana, C., Cabanac, R., Cappi, A., Carvalho, C. S., Castignani, G., Castro, T., {n}as-Herrera, G. Ca\, Chambers, K. C., Cooray, A. R., Coupon, J., Davini, S., de la Torre, S., De Lucia, G., Desprez, G., Di Domizio, S., Dole, H., Díaz-Sánchez, A., Vigo, J. A. Escartin, Escoffier, S., Ferreira, P. G., Ferrero, I., Finelli, F., Gabarra, L., Ganga, K., García-Bellido, J., Giacomini, F., Gozaliasl, G., Guinet, D., Hildebrandt, H., Ilić, S., {n}oz, A. Jimenez Mu\, Joudaki, S., Kajava, J. J. E., Kansal, V., Kirkpatrick, C. C., Legrand, L., Loureiro, A., Magliocchetti, M., Mainetti, G., Maoli, R., Martinelli, M., Martins, C. J. A. P., Matthew, S., Maturi, M., Maurin, L., Metcalf, R. B., Migliaccio, M., Monaco, P., Morgante, G., Nadathur, S., Patrizii, L., Pezzotta, A., Popa, V., Porciani, C., Potter, D., Pöntinen, M., Reimberg, P., Rocci, P. -F., Sánchez, A. G., Schneider, A., Schultheis, M., Sefusatti, E., Sereno, M., Silvestri, A., Simon, P., Mancini, A. Spurio, Steinwagner, J., Testera, G., Tewes, M., Teyssier, R., Toft, S., Tosi, S., Troja, A., Tucci, M., Valiviita, J., Vergani, D., and Tanidis, K.
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Astrophysics - Cosmology and Nongalactic Astrophysics - Abstract
In this paper we investigate the impact of lensing magnification on the analysis of Euclid's spectroscopic survey, using the multipoles of the 2-point correlation function for galaxy clustering. We determine the impact of lensing magnification on cosmological constraints, and the expected shift in the best-fit parameters if magnification is ignored. We consider two cosmological analyses: i) a full-shape analysis based on the $\Lambda$CDM model and its extension $w_0w_a$CDM and ii) a model-independent analysis that measures the growth rate of structure in each redshift bin. We adopt two complementary approaches in our forecast: the Fisher matrix formalism and the Markov chain Monte Carlo method. The fiducial values of the local count slope (or magnification bias), which regulates the amplitude of the lensing magnification, have been estimated from the Euclid Flagship simulations. We use linear perturbation theory and model the 2-point correlation function with the public code coffe. For a $\Lambda$CDM model, we find that the estimation of cosmological parameters is biased at the level of 0.4-0.7 standard deviations, while for a $w_0w_a$CDM dynamical dark energy model, lensing magnification has a somewhat smaller impact, with shifts below 0.5 standard deviations. In a model-independent analysis aiming to measure the growth rate of structure, we find that the estimation of the growth rate is biased by up to $1.2$ standard deviations in the highest redshift bin. As a result, lensing magnification cannot be neglected in the spectroscopic survey, especially if we want to determine the growth factor, one of the most promising ways to test general relativity with Euclid. We also find that, by including lensing magnification with a simple template, this shift can be almost entirely eliminated with minimal computational overhead., Comment: 23 pages, 14 figures
- Published
- 2023
136. Euclid preparation. XXXIX. The effect of baryons on the Halo Mass Function
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Euclid Collaboration, Castro, T., Borgani, S., Costanzi, M., Dakin, J., Dolag, K., Fumagalli, A., Ragagnin, A., Saro, A., Brun, A. M. C. Le, Aghanim, N., Amara, A., Andreon, S., Auricchio, N., Baldi, M., Bardelli, S., Bodendorf, C., Bonino, D., Branchini, E., Brescia, M., Brinchmann, J., Camera, S., Capobianco, V., Carbone, C., Carretero, J., Casas, S., Castellano, M., Cavuoti, S., Cimatti, A., Congedo, G., Conselice, C. J., Conversi, L., Copin, Y., Corcione, L., Courbin, F., Courtois, H. M., Cropper, M., Da Silva, A., Degaudenzi, H., Di Giorgio, A. M., Dinis, J., Dubath, F., Duncan, C. A. J., Dupac, X., Farina, M., Farrens, S., Ferriol, S., Frailis, M., Franceschi, E., Fumana, M., Galeotta, S., Gillis, B., Giocoli, C., Grazian, A., Grupp, F., Haugan, S. V. H., Holmes, W., Hormuth, F., Hornstrup, A., Jahnke, K., Keihänen, E., Kermiche, S., Kiessling, A., Kilbinger, M., Kubik, B., Kunz, M., Kurki-Suonio, H., Ligori, S., Lilje, P. B., Lindholm, V., Lloro, I., Maiorano, E., Mansutti, O., Marggraf, O., Markovic, K., Martinet, N., Marulli, F., Massey, R., Maurogordato, S., Medinaceli, E., Meneghetti, M., Merlin, E., Meylan, G., Moresco, M., Moscardini, L., Munari, E., Niemi, S. -M., Padilla, C., Paltani, S., Pasian, F., Pettorino, V., Pires, S., Polenta, G., Poncet, M., Popa, L. A., Pozzetti, L., Raison, F., Rebolo, R., Renzi, A., Rhodes, J., Riccio, G., Romelli, E., Roncarelli, M., Saglia, R., Sapone, D., Sartoris, B., Schneider, P., Schrabback, T., Secroun, A., Seidel, G., Serrano, S., Sirignano, C., Sirri, G., Stanco, L., Starck, J. -L., Tallada-Crespí, P., Taylor, A. N., Tereno, I., Toledo-Moreo, R., Torradeflot, F., Tutusaus, I., Valentijn, E. A., Valenziano, L., Vassallo, T., Veropalumbo, A., Wang, Y., Weller, J., Zacchei, A., Zamorani, G., Zoubian, J., Zucca, E., Biviano, A., Bozzo, E., Cerna, C., Colodro-Conde, C., Di Ferdinando, D., Mauri, N., Neissner, C., Sakr, Z., Scottez, V., Tenti, M., Viel, M., Wiesmann, M., Akrami, Y., Anselmi, S., Baccigalupi, C., Ballardini, M., Borlaff, A. S., Bruton, S., Burigana, C., Cabanac, R., Cappi, A., Carvalho, C. S., Castignani, G., Cañas-Herrera, G., Chambers, K. C., Cooray, A. R., Coupon, J., Cucciati, O., Díaz-Sánchez, A., Davini, S., de la Torre, S., De Lucia, G., Desprez, G., Di Domizio, S., Dole, H., Escoffier, S., Ferrero, I., Finelli, F., Gabarra, L., Ganga, K., Garcia-Bellido, J., Giacomini, F., Gozaliasl, G., Hildebrandt, H., Ilić, S., Munñoz, A. Jimanez, Kajava, J. J. E., Kansal, V., Kirkpatrick, C. C., Legrand, L., Loureiro, A., Macias-Perez, J., Magliocchetti, M., Mainetti, G., Maoli, R., Martinelli, M., Martins, C. J. A. P., Matthew, S., Maturi, M., Maurin, L., Metcalf, R. B., Migliaccio, M., Monaco, P., Morgante, G., Nadathur, S., Patrizii, L., Pezzotta, A., Popa, V., Porciani, C., Potter, D., Pöntinen, M., Reimberg, P., Rocci, P. -F., Sánchez, A. G., Schaye, J., Schneider, A., Sefusatti, E., Sereno, M., Simon, P., Mancini, A. Spurio, Stadel, J., Stanford, S. A., Steinwagner, J., Testera, G., Tewes, M., Teyssier, R., Toft, S., Tosi, S., Troja, A., Tucci, M., Valiviita, J., and Vergani, D.
- Subjects
Astrophysics - Cosmology and Nongalactic Astrophysics - Abstract
The Euclid photometric survey of galaxy clusters stands as a powerful cosmological tool, with the capacity to significantly propel our understanding of the Universe. Despite being sub-dominant to dark matter and dark energy, the baryonic component in our Universe holds substantial influence over the structure and mass of galaxy clusters. This paper presents a novel model to precisely quantify the impact of baryons on galaxy cluster virial halo masses, using the baryon fraction within a cluster as proxy for their effect. Constructed on the premise of quasi-adiabaticity, the model includes two parameters calibrated using non-radiative cosmological hydrodynamical simulations and a single large-scale simulation from the Magneticum set, which includes the physical processes driving galaxy formation. As a main result of our analysis, we demonstrate that this model delivers a remarkable one percent relative accuracy in determining the virial dark matter-only equivalent mass of galaxy clusters, starting from the corresponding total cluster mass and baryon fraction measured in hydrodynamical simulations. Furthermore, we demonstrate that this result is robust against changes in cosmological parameters and against varying the numerical implementation of the sub-resolution physical processes included in the simulations. Our work substantiates previous claims about the impact of baryons on cluster cosmology studies. In particular, we show how neglecting these effects would lead to biased cosmological constraints for a Euclid-like cluster abundance analysis. Importantly, we demonstrate that uncertainties associated with our model, arising from baryonic corrections to cluster masses, are sub-dominant when compared to the precision with which mass-observable relations will be calibrated using Euclid, as well as our current understanding of the baryon fraction within galaxy clusters., Comment: 18 pages, 10 figures, 4 tables, 1 appendix, abstract abridged for arXiv submission; v2 matches published version
- Published
- 2023
137. Euclid preparation. TBD. Forecast impact of super-sample covariance on 3x2pt analysis with Euclid
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Euclid Collaboration, Sciotti, D., Beauchamps, S. Gouyou, Cardone, V. F., Camera, S., Tutusaus, I., Lacasa, F., Barreira, A., Gorce, A., Aubert, M., Baratta, P., Upham, R. E., Bonici, M., Carbone, C., Casas, S., Ilić, S., Martinelli, M., Sakr, Z., Schneider, A., Maoli, R., Scaramella, R., Escoffier, S., Gillard, W., Aghanim, N., Amara, A., Andreon, S., Auricchio, N., Baldi, M., Bardelli, S., Bonino, D., Branchini, E., Brescia, M., Brinchmann, J., Capobianco, V., Carretero, J., Castander, F. J., Castellano, M., Cavuoti, S., Cimatti, A., Cledassou, R., Congedo, G., Conselice, C. J., Conversi, L., Copin, Y., Corcione, L., Courbin, F., Courtois, H. M., Cropper, M., Da Silva, A., Degaudenzi, H., Dinis, J., Dubath, F., Dupac, X., Dusini, S., Farina, M., Farrens, S., Fosalba, P., Frailis, M., Franceschi, E., Fumana, M., Galeotta, S., Garilli, B., Gillis, B., Giocoli, C., Grazian, A., Grupp, F., Guzzo, L., Haugan, S. V. H., Holmes, W., Hook, I., Hormuth, F., Hornstrup, A., Hudelot, P., Jahnke, K., Joachimi, B., Keihänen, E., Kermiche, S., Kiessling, A., Kunz, M., Kurki-Suonio, H., Lilje, P. B., Lindholm, V., Lloro, I., Maino, D., Mansutti, O., Marggraf, O., Markovic, K., Martinet, N., Marulli, F., Massey, R., Maurogordato, S., Medinaceli, E., Mei, S., Mellier, Y., Meneghetti, M., Meylan, G., Moresco, M., Moscardini, L., Munari, E., Niemi, S. -M., Padilla, C., Paltani, S., Pasian, F., Pedersen, K., Pettorino, V., Pires, S., Polenta, G., Poncet, M., Popa, L. A., Raison, F., Rebolo, R., Renzi, A., Rhodes, J., Riccio, G., Romelli, E., Roncarelli, M., Saglia, R., Sapone, D., Sartoris, B., Schirmer, M., Schneider, P., Secroun, A., Seidel, G., Serrano, S., Sirignano, C., Sirri, G., Stanco, L., Starck, J. -L., Tallada-Crespí, P., Taylor, A. N., Tereno, I., Toledo-Moreo, R., Torradeflot, F., Valentijn, E. A., Valenziano, L., Vassallo, T., Veropalumbo, A., Wang, Y., Weller, J., Zacchei, A., Zamorani, G., Zoubian, J., Zucca, E., Biviano, A., Boucaud, A., Bozzo, E., Colodro-Conde, C., Di Ferdinando, D., Farinelli, R., Graciá-Carpio, J., Mauri, N., Neissner, C., Scottez, V., Tenti, M., Akrami, Y., Allevato, V., Baccigalupi, C., Ballardini, M., Bernardeau, F., Blanchard, A., Borgani, S., Borlaff, A. S., Burigana, C., Cabanac, R., Cappi, A., Carvalho, C. S., Castignani, G., Castro, T., {n}as-Herrera, G. Ca\, Chambers, K. C., Cooray, A. R., Coupon, J., Díaz-Sánchez, A., Davini, S., De Lucia, G., Desprez, G., Di Domizio, S., Vigo, J. A. Escartin, Ferrero, I., Finelli, F., Gabarra, L., Ganga, K., Garcia-Bellido, J., Gaztanaga, E., Giacomini, F., Gozaliasl, G., Hildebrandt, H., Jacobson, J., Kajava, J. J. E., Kansal, V., Kirkpatrick, C. C., Legrand, L., Loureiro, A., Macias-Perez, J., Magliocchetti, M., Mainetti, G., Martins, C. J. A. P., Matthew, S., Maurin, L., Metcalf, R. B., Migliaccio, M., Monaco, P., Morgante, G., Nadathur, S., Nucita, A. A., Pöntinen, M., Patrizii, L., Popa, V., Porciani, C., Potter, D., Pourtsidou, A., Sánchez, A. G., Sefusatti, E., Sereno, M., Simon, P., Mancini, A. Spurio, Stadel, J., Steinwagner, J., Teyssier, R., Toft, S., Tucci, M., Valieri, C., Valiviita, J., and Viel, M.
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Astrophysics - Cosmology and Nongalactic Astrophysics - Abstract
Deviations from Gaussianity in the distribution of the fields probed by large-scale structure surveys generate additional terms in the data covariance matrix, increasing the uncertainties in the measurement of the cosmological parameters. Super-sample covariance (SSC) is among the largest of these non-Gaussian contributions, with the potential to significantly degrade constraints on some of the parameters of the cosmological model under study -- especially for weak lensing cosmic shear. We compute and validate the impact of SSC on the forecast uncertainties on the cosmological parameters for the Euclid photometric survey, obtained with a Fisher matrix analysis, both considering the Gaussian covariance alone and adding the SSC term -- computed through the public code PySSC. The photometric probes are considered in isolation and combined in the `3$\times$2pt' analysis. We find the SSC impact to be non-negligible -- halving the Figure of Merit of the dark energy parameters ($w_0$, $w_a$) in the 3$\times$2pt case and substantially increasing the uncertainties on $\Omega_{{\rm m},0}, w_0$, and $\sigma_8$ for cosmic shear; photometric galaxy clustering, on the other hand, is less affected due to the lower probe response. The relative impact of SSC does not show significant changes under variations of the redshift binning scheme, while it is smaller for weak lensing when marginalising over the multiplicative shear bias nuisance parameters, which also leads to poorer constraints on the cosmological parameters. Finally, we explore how the use of prior information on the shear and galaxy bias changes the SSC impact. Improving shear bias priors does not have a significant impact, while galaxy bias must be calibrated to sub-percent level to increase the Figure of Merit by the large amount needed to achieve the value when SSC is not included., Comment: 22 pages, 13 figures
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- 2023
138. Euclid preparation. XXXI. The effect of the variations in photometric passbands on photometric-redshift accuracy
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Euclid Collaboration, Paltani, Stéphane, Coupon, J., Hartley, W. G., Alvarez-Ayllon, A., Dubath, F., Mohr, J. J., Schirmer, M., Cuillandre, J. -C., Desprez, G., Ilbert, O., Kuijken, K., Aghanim, N., Altieri, B., Amara, A., Auricchio, N., Baldi, M., Bender, R., Bodendorf, C., Bonino, D., Branchini, E., Brescia, M., Brinchmann, J., Camera, S., Capobianco, V., Carbone, C., Cardone, V. F., Carretero, J., Castander, F. J., Castellano, M., Cavuoti, S., Cledassou, R., Congedo, G., Conselice, C. J., Conversi, L., Copin, Y., Corcione, L., Courbin, F., Cropper, M., Da Silva, A., Degaudenzi, H., Dinis, J., Douspis, M., Dupac, X., Dusini, S., Farrens, S., Ferriol, S., Fosalba, P., Frailis, M., Franceschi, E., Franzetti, P., Galeotta, S., Garilli, B., Gillard, W., Gillis, B., Giocoli, C., Grazian, A., Haugan, S. V., Hoekstra, H., Hornstrup, A., Hudelot, P., Jahnke, K., Kümmel, M., Kermiche, S., Kiessling, A., Kilbinger, M., Kitching, T., Kohley, R., Kubik, B., Kunz, M., Kurki-Suonio, H., Ligori, S., Lilje, P. B., Lloro, I., Maiorano, E., Mansutti, O., Marggraf, O., Markovic, K., Marulli, F., Massey, R., Masters, D. C., Maurogordato, S., McCracken, H. J., Medinaceli, E., Mei, S., Melchior, M., Meneghetti, M., Merlin, E., Meylan, G., Moresco, M., Moscardini, L., Munari, E., Niemi, S. -M., Nightingale, J., Padilla, C., Pasian, F., Pedersen, K., Percival, W. J., Pettorino, V., Polenta, G., Poncet, M., Popa, L. A., Raison, F., Rebolo, R., Renzi, A., Rhodes, J., Riccio, G., Romelli, E., Roncarelli, M., Rossetti, E., Saglia, R., Sapone, D., Sartoris, B., Schneider, P., Secroun, A., Sirignano, C., Sirri, G., Skottfelt, J., Stanco, L., Starck, J. -L., Surace, C., Tallada-Crespí, P., Tereno, I., Toledo-Moreo, R., Torradeflot, F., Tutusaus, I., Valentijn, E. A., Valenziano, L., Vassallo, T., Wang, Y., Zamorani, G., Zoubian, J., Andreon, S., Aussel, H., Bardelli, S., Bolzonella, M., Boucaud, A., Di Ferdinando, D., Farina, M., Graciá-Carpio, J., Lindholm, V., Maino, D., Mauri, N., Neissner, C., Scottez, V., Zucca, E., Baccigalupi, C., Ballardini, M., Biviano, A., Blanchard, A., Borgani, S., Borlaff, A. S., Burigana, C., Cabanac, R., Cappi, A., Carvalho, C. S., Casas, S., Castignani, G., Chambers, K., Cooray, A. R., Courtois, H. M., Cucciati, O., Davini, S., De Lucia, G., Dole, H., Escartin, J. A., Escoffier, S., Finelli, F., Fotopoulou, S., Ganga, K., George, K., Gozaliasl, G., Hildebrandt, H., Hook, I., Muñoz, A. Jimenez, Joachimi, B., Kansal, V., Keihanen, E., Kirkpatrick, C. C., Loureiro, A., Macias-Perez, J., Maggio, G., Magliocchetti, M., Maoli, R., Marcin, S., Martinelli, M., Martinet, N., Matthew, S., Maurin, L., Metcalf, R. B., Monaco, P., Morgante, G., Nadathur, S., Nucita, A. A., Patrizii, L., Pollack, J. E., Popa, V., Porciani, C., Potter, D., Pourtsidou, A., Pozzetti, L., Pöntinen, M., Reimberg, P., Sánchez, A. G., Sakr, Z., Sefusatti, E., Sereno, M., Mancini, A. Spurio, Stadel, J., Steinwagner, J., Teyssier, R., Valieri, C., Valiviita, J., van Mierlo, S. E., Veropalumbo, A., Viel, M., and Weaver, J. R.
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Astrophysics - Cosmology and Nongalactic Astrophysics - Abstract
The technique of photometric redshifts has become essential for the exploitation of multi-band extragalactic surveys. While the requirements on photo-zs for the study of galaxy evolution mostly pertain to the precision and to the fraction of outliers, the most stringent requirement in their use in cosmology is on the accuracy, with a level of bias at the sub-percent level for the Euclid cosmology mission. A separate, and challenging, calibration process is needed to control the bias at this level of accuracy. The bias in photo-zs has several distinct origins that may not always be easily overcome. We identify here one source of bias linked to the spatial or time variability of the passbands used to determine the photometric colours of galaxies. We first quantified the effect as observed on several well-known photometric cameras, and found in particular that, due to the properties of optical filters, the redshifts of off-axis sources are usually overestimated. We show using simple simulations that the detailed and complex changes in the shape can be mostly ignored and that it is sufficient to know the mean wavelength of the passbands of each photometric observation to correct almost exactly for this bias; the key point is that this mean wavelength is independent of the spectral energy distribution of the source}. We use this property to propose a correction that can be computationally efficiently implemented in some photo-z algorithms, in particular template-fitting. We verified that our algorithm, implemented in the new photo-z code Phosphoros, can effectively reduce the bias in photo-zs on real data using the CFHTLS T007 survey, with an average measured bias Delta z over the redshift range 0.4
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- 2023
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139. Strategies to mitigate bias from time recording errors in pharmacokinetic studies
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Weeks, Hannah L and Shotwell, Matthew S
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Statistics - Applications ,Statistics - Methodology - Abstract
Opportunistic pharmacokinetic (PK) studies have sparse and imbalanced clinical measurement data, and the impact of sample time errors is an important concern when seeking accurate estimates of treatment response. We evaluated an approximate Bayesian model for individualized pharmacokinetics in the presence of time recording errors (TREs), considering both a short and long infusion dosing pattern. We found that the long infusion schedule generally had lower bias in estimates of the pharmacodynamic (PD) endpoint relative to the short infusion schedule. We investigated three different design strategies for their ability to mitigate the impact of TREs: (i) shifting blood draws taken during an active infusion to the post-infusion period, (ii) identifying the best next sample time by minimizing bias in the presence of TREs, and (iii) collecting additional information on a subset of patients based on estimate uncertainty or quadrature-estimated variance in the presence of TREs. Generally, the proposed strategies led to a decrease in bias of the PD estimate for the short infusion schedule, but had a negligible impact for the long infusion schedule. Dosing regimens with periods of high non-linearity may benefit from design modifications, while more stable concentration-time profiles are generally more robust to TREs with no design modifications.
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- 2023
140. XUE. Molecular inventory in the inner region of an extremely irradiated Protoplanetary Disk
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Ramirez-Tannus, María Claudia, Bik, Arjan, Cuijpers, Lars, Waters, Rens, Goppl, Christiane, Henning, Thomas, Kamp, Inga, Preibisch, Thomas, Getman, Konstantin V., Chaparro, Germán, Cuartas-Restrepo, Pablo, de Koter, Alex, Feigelson, Eric D., Grant, Sierra L., Haworth, Thomas J., Hernández, Sebastián, Kuhn, Michael A., Perotti, Giulia, Povich, Matthew S., Reiter, Megan, Roccatagliata, Veronica, Sabbi, Elena, Tabone, Benoît, Winter, Andrew J., McLeod, Anna F., van Boekel, Roy, and van Terwisga, Sierk E.
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Astrophysics - Solar and Stellar Astrophysics ,Astrophysics - Earth and Planetary Astrophysics ,Astrophysics - Astrophysics of Galaxies - Abstract
We present the first results of the eXtreme UV Environments (XUE) James Webb Space Telescope (JWST) program, that focuses on the characterization of planet forming disks in massive star forming regions. These regions are likely representative of the environment in which most planetary systems formed. Understanding the impact of environment on planet formation is critical in order to gain insights into the diversity of the observed exoplanet populations. XUE targets 15 disks in three areas of NGC 6357, which hosts numerous massive OB stars, among which some of the most massive stars in our Galaxy. Thanks to JWST we can, for the first time, study the effect of external irradiation on the inner ($< 10$ au), terrestrial-planet forming regions of proto-planetary disks. In this study, we report on the detection of abundant water, CO, CO$_2$, HCN and C$_2$H$_2$ in the inner few au of XUE 1, a highly irradiated disk in NGC 6357. In addition, small, partially crystalline silicate dust is present at the disk surface. The derived column densities, the oxygen-dominated gas-phase chemistry, and the presence of silicate dust are surprisingly similar to those found in inner disks located in nearby, relatively isolated low-mass star-forming regions. Our findings imply that the inner regions of highly irradiated disks can retain similar physical and chemical conditions as disks in low-mass star-forming regions, thus broadening the range of environments with similar conditions for inner disk rocky planet formation to the most extreme star-forming regions in our Galaxy., Comment: Accepted for publication in ApJ Letters. 20 pages, 7 figures
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- 2023
141. Full-scale modal testing of a Hawk T1A aircraft for benchmarking vibration-based methods
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Haywood-Alexander, Marcus, Mills, Robin S., Champneys, Max D., Jones, Matthew R., Bonney, Matthew S., Wagg, David, and Rogers, Timothy J.
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Electrical Engineering and Systems Science - Systems and Control - Abstract
Research developments for structural dynamics in the fields of design, system identification and structural health monitoring (SHM) have dramatically expanded the bounds of what can be learned from measured vibration data. However, significant challenges remain in the tasks of identification, prediction and evaluation of full-scale structures. A significant aid in the roadmap to the application of cutting-edge methods to the demands of in-service engineering structures, is the development of comprehensive benchmark datasets. With the aim of developing a useful and worthwhile benchmark dataset for structural dynamics, an extensive testing campaign is presented here. This recent campaign was performed on a decommissioned BAE system Hawk T1A aircraft at the Laboratory for Verification and Validation (LVV) in Sheffield. The aim of this paper is to present the dataset, providing details on the structure, experimental design, and data acquired. The collected data is made freely and openly available with the intention that it serve as a benchmark dataset for challenges in full-scale structural dynamics. Here, the details pertaining to two test phases (frequency and time domain) are presented. So as to ensure that the presented dataset is able to function as a benchmark, some baseline-level results are additionally presented for the tasks of identification and prediction, using standard approaches. It is envisaged that advanced methodologies will demonstrate superiority by favourable comparison with the results presented here. Finally, some dataset-specific challenges are described, with a view to form a hierarchy of tasks and frame discussion over their relative difficulty.
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- 2023
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142. Magnetic instability and spin-glass order beyond the Anderson-Mott transition in interacting power-law random banded matrix fermions
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Zhang, Xinghai and Foster, Matthew S.
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Condensed Matter - Disordered Systems and Neural Networks ,Condensed Matter - Mesoscale and Nanoscale Physics ,Condensed Matter - Statistical Mechanics - Abstract
In the presence of quenched disorder, the interplay between local magnetic-moment formation and Anderson localization for electrons at a zero-temperature, metal-insulator transition (MIT) remains a long unresolved problem. Here, we study the emergence of these phenomena in a power-law random banded matrix model of spin-1/2 fermions with repulsive Hubbard interactions. Focusing on the regime of weak interactions, we perform both analytical field theory and numerical self-consistent Hartree-Fock calculations. We show that interference-mediated effects strongly enhance the density of states and magnetic fluctuations upon approaching the MIT from the metallic side. These are consistent with results due to Finkel'stein obtained four decades ago. Our numerics further show that local moments nucleate from typical states as we cross the MIT, with a density that grows continuously into the insulating phase. We identify spin-glass order in the insulator by computing the overlap distribution between converged Hartree-Fock mean-field moment profiles. Our results indicate that itinerant interference effects can morph smoothly into moment formation and magnetic frustration within a single model, revealing a common origin for these disparate phenomena., Comment: v2: 25 pages, 21 figures; published version
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- 2023
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143. Saturn's Atmosphere in Northern Summer Revealed by JWST/MIRI
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Fletcher, Leigh N., King, Oliver R. T., Harkett, Jake, Hammel, Heidi B., Roman, Michael T., Melin, Henrik, Hedman, Matthew M., Moses, Julianne I., Guerlet, Sandrine, Milam, Stefanie N., and Tiscareno, Matthew S.
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Astrophysics - Earth and Planetary Astrophysics - Abstract
Saturn's northern summertime hemisphere was mapped by JWST/MIRI (4.9-27.9 $\mu$m) in November 2022, tracing the seasonal evolution of temperatures, aerosols, and chemical species in the five years since the end of the Cassini mission. The spectral region between reflected sunlight and thermal emission (5.1-6.8 $\mu$m) is mapped for the first time, enabling retrievals of phosphine, ammonia, and water, alongside a system of two aerosol layers (an upper tropospheric haze $p<0.3$ bars, and a deeper cloud layer at 1-2 bars). Ammonia displays substantial equatorial enrichment, suggesting similar dynamical processes to those found in Jupiter's equatorial zone. Saturn's North Polar Stratospheric Vortex has warmed since 2017, entrained by westward winds at $p<10$ mbar, and exhibits localised enhancements in several hydrocarbons. The strongest latitudinal temperature gradients are co-located with the peaks of the zonal winds, implying wind decay with altitude. Reflectivity contrasts at 5-6 $\mu$m compare favourably with albedo contrasts observed by Hubble, and several discrete vortices are observed. A warm equatorial stratospheric band in 2022 is not consistent with a 15-year repeatability for the equatorial oscillation. A stacked system of windshear zones dominates Saturn's equatorial stratosphere, and implies a westward equatorial jet near 1-5 mbar at this epoch. Lower stratospheric temperatures, and local minima in the distributions of several hydrocarbons, imply low-latitude upwelling and a reversal of Saturn's interhemispheric circulation since equinox. Latitudinal distributions of stratospheric ethylene, benzene, methyl and carbon dioxide are presented for the first time, and we report the first detection of propane bands in the 8-11 $\mu$m region., Comment: 53 pages, 25 figures, accepted for publication in JGR: Planets
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- 2023
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144. A race against the clock: Constraining the timing of cometary bombardment relative to Earth's growth
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Joiret, Sarah, Raymond, Sean N., Avice, Guillaume, Clement, Matthew S., Deienno, Rogerio, and Nesvorný, David
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Astrophysics - Earth and Planetary Astrophysics - Abstract
Comets are considered a potential source of inner solar system volatiles, but the timing of this delivery relative to that of Earth's accretion is still poorly understood. Measurements of xenon isotopes in comet 67P/Churyumov-Gerasimenko revealed that comets partly contributed to the Earth's atmosphere. However, there is no conclusive evidence of a significant cometary component in the Earth's mantle. These geochemical constraints would favour a contribution of comets mainly occurring after the last stages of Earth's formation. Here, we evaluate whether dynamical simulations satisfy these constraints in the context of an Early Instability model. We perform dynamical simulations of the solar system, calculate the probability of collision between comets and Earth analogs component embryos through time and estimate the total cometary mass accreted in Earth analogs as a function of time. While our results are in excellent agreement with geochemical constraints, we also demonstrate that the contribution of comets on Earth might have been delayed with respect to the timing of the instability, due to a stochastic component of the bombardment. More importantly, we show that it is possible that enough cometary mass has been brought to Earth after it had finished forming so that the xenon constraint is not necessarily in conflict with an Early Instability scenario. However, it appears very likely that a few comets were delivered to Earth early in its accretion history, thus contributing to the mantle's budget. Finally, we compare the delivery of cometary material on Earth to Venus and Mars. These results emphasize the stochastic nature of the cometary bombardment in the inner solar system., Comment: 26 pages, 12 figures
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- 2023
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145. Molecular Insights into O‑Linked Sialoglycans Recognition by the Siglec-Like SLBR‑N (SLBRUB10712) of Streptococcus gordonii
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Di Carluccio, Cristina, Cerofolini, Linda, Moreira, Miguel, Rosu, Frédéric, Padilla-Cortés, Luis, Gheorghita, Giulia Roxana, Xu, Zhuojia, Santra, Abhishek, Yu, Hai, Yokoyama, Shinji, Gray, Taylor E, St. Laurent, Chris D, Manabe, Yoshiyuki, Chen, Xi, Fukase, Koichi, Macauley, Matthew S, Molinaro, Antonio, Li, Tiehai, Bensing, Barbara A, Marchetti, Roberta, Gabelica, Valérie, Fragai, Marco, and Silipo, Alba
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Chemical Sciences ,Clinical Research ,Infectious Diseases ,Dental/Oral and Craniofacial Disease ,Chemical sciences - Abstract
Streptococcus gordonii is a Gram-positive bacterial species that typically colonizes the human oral cavity, but can also cause local or systemic diseases. Serine-rich repeat (SRR) glycoproteins exposed on the S. gordonii bacterial surface bind to sialylated glycans on human salivary, plasma, and platelet glycoproteins, which may contribute to oral colonization as well as endocardial infections. Despite a conserved overall domain organization of SRR adhesins, the Siglec-like binding regions (SLBRs) are highly variable, affecting the recognition of a wide range of sialoglycans. SLBR-N from the SRR glycoprotein of S. gordonii UB10712 possesses the remarkable ability to recognize complex core 2 O-glycans. We here employed a multidisciplinary approach, including flow cytometry, native mass spectrometry, isothermal titration calorimetry, NMR spectroscopy from both protein and ligand perspectives, and computational methods, to investigate the ligand specificity and binding preferences of SLBR-N when interacting with mono- and disialylated core 2 O-glycans. We determined the means by which SLBR-N preferentially binds branched α2,3-disialylated core 2 O-glycans: a selected conformation of the 3'SLn branch is accommodated into the main binding site, driving the sTa branch to further interact with the protein. At the same time, SLBR-N assumes an open conformation of the CD loop of the glycan-binding pocket, allowing one to accommodate the entire complex core 2 O-glycan. These findings establish the basis for the generation of novel tools for the detection of specific complex O-glycan structures and pave the way for the design and development of potential therapeutics against streptococcal infections.
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- 2024
146. Associations between Social Adversity and Biomarkers of Inflammation, Stress, and Aging in Children
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Pantell, Matthew S, Silveira, Patricia P, de Mendonça Filho, Euclides José, Wing, Holly, Brown, Erika M, Keeton, Victoria F, Pokhvisneva, Irina, O’Donnell, Kieran J, Neuhaus, John, Hessler, Danielle, Meaney, Michael J, Adler, Nancy E, and Gottlieb, Laura M
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Paediatrics ,Biomedical and Clinical Sciences ,Pediatric Research Initiative ,Prevention ,Behavioral and Social Science ,Brain Disorders ,Pediatric ,Aetiology ,2.3 Psychological ,social and economic factors ,Inflammatory and immune system ,Paediatrics and Reproductive Medicine ,Public Health and Health Services ,Pediatrics - Abstract
BackgroundPrior work has found relationships between childhood social adversity and biomarkers of stress, but knowledge gaps remain. To help address these gaps, we explored associations between social adversity and biomarkers of inflammation (interleukin-1β [IL-1β], IL-6, IL-8, tumor necrosis factor-alpha [TNF-α], and salivary cytokine hierarchical "clusters" based on the three interleukins), neuroendocrine function (cortisol, cortisone, dehydroepiandrosterone, testosterone, and progesterone), neuromodulation (N-arachidonoylethanolamine, stearoylethanolamine, oleoylethanolamide, and palmitoylethanolamide), and epigenetic aging (Pediatric-Buccal-Epigenetic clock).MethodsWe collected biomarker samples of children ages 0-17 recruited from an acute care pediatrics clinic and examined their associations with caregiver-endorsed education, income, social risk factors, and cumulative adversity. We calculated regression-adjusted means for each biomarker and compared associations with social factors using Wald tests. We used logistic regression to predict being in the highest cytokine cluster based on social predictors.ResultsOur final sample included 537 children but varied based on each biomarker. Cumulative social adversity was significantly associated with having higher levels of all inflammatory markers and with cortisol, displaying a U-shaped distribution. There were no significant relationships between cumulative social adversity and cortisone, neuromodulation biomarkers or epigenetic aging.ConclusionOur findings support prior work suggesting that social stress exposures contribute to increased inflammation in children.ImpactOur study is one of the largest studies examining associations between childhood social adversity and biomarkers of inflammation, neuroendocrine function, neuromodulation, and epigenetic aging. It is one of the largest studies to link childhood social adversity to biomarkers of inflammation, and the first of which we are aware to link cumulative social adversity to cytokine clusters. It is also one of the largest studies to examine associations between steroids and epigenetic aging among children, and one of the only studies of which we are aware to examine associations between social adversity and endocannabinoids among children.Clinical trial registrationNCT02746393.
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- 2024
147. Childhood Disadvantage Moderates Late Midlife Default Mode Network Cortical Microstructure and Visual Memory Association
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Tang, Rongxiang, Elman, Jeremy A, Dale, Anders M, Dorros, Stephen M, Eyler, Lisa T, Fennema-Notestine, Christine, Gustavson, Daniel E, Hagler, Donald J, Lyons, Michael J, Panizzon, Matthew S, Puckett, Olivia K, Reynolds, Chandra A, Franz, Carol E, and Kremen, William S
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Biomedical and Clinical Sciences ,Health Sciences ,Clinical Research ,Behavioral and Social Science ,Dementia ,Aging ,Neurodegenerative ,Mental Health ,Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD) ,Basic Behavioral and Social Science ,Acquired Cognitive Impairment ,Neurosciences ,Alzheimer's Disease ,Brain Disorders ,2.1 Biological and endogenous factors ,Male ,Humans ,Aged ,Child ,Default Mode Network ,Magnetic Resonance Imaging ,Brain ,Memory ,Episodic ,Episodic memory ,Mean diffusivity ,Neurodegeneration ,Socioeconomic status ,Clinical Sciences ,Gerontology ,Biomedical and clinical sciences ,Health sciences - Abstract
BackgroundChildhood disadvantage is a prominent risk factor for cognitive and brain aging. Childhood disadvantage is associated with poorer episodic memory in late midlife and functional and structural brain abnormalities in the default mode network (DMN). Although age-related changes in DMN are associated with episodic memory declines in older adults, it remains unclear if childhood disadvantage has an enduring impact on this later-life brain-cognition relationship earlier in the aging process. Here, within the DMN, we examined whether its cortical microstructural integrity-an early marker of structural vulnerability that increases the risk for future cognitive decline and neurodegeneration-is associated with episodic memory in adults at ages 56-66, and whether childhood disadvantage moderates this association.MethodsCortical mean diffusivity (MD) obtained from diffusion magnetic resonance imaging was used to measure microstructural integrity in 350 community-dwelling men. We examined both visual and verbal episodic memory in relation to DMN MD and divided participants into disadvantaged and nondisadvantaged groups based on parental education and occupation.ResultsHigher DMN MD was associated with poorer visual memory but not verbal memory (β = -0.11, p = .040 vs β = -0.04, p = .535). This association was moderated by childhood disadvantage and was significant only in the disadvantaged group (β = -0.26, p = .002 vs β = -0.00, p = .957).ConclusionsLower DMN cortical microstructural integrity may reflect visual memory vulnerability in cognitively normal adults earlier in the aging process. Individuals who experienced childhood disadvantage manifested greater vulnerability to cortical microstructure-related visual memory dysfunction than their nondisadvantaged counterparts who exhibited resilience in the face of low cortical microstructural integrity.
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- 2024
148. Associations of plasma neurofilament light chain with cognition and neuroimaging measures in community-dwelling early old age men
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Tang, Rongxiang, Buchholz, Erik, Dale, Anders M, Rissman, Robert A, Fennema-Notestine, Christine, Gillespie, Nathan A, Hagler, Donald J, Lyons, Michael J, Neale, Michael C, Panizzon, Matthew S, Puckett, Olivia K, Reynolds, Chandra A, Franz, Carol E, Kremen, William S, and Elman, Jeremy A
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Biomedical and Clinical Sciences ,Health Sciences ,Brain Disorders ,Mental Health ,Health Disparities ,Prevention ,Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD) ,Aging ,Neurodegenerative ,Dementia ,Acquired Cognitive Impairment ,Basic Behavioral and Social Science ,Clinical Research ,Neurosciences ,Alzheimer's Disease ,Behavioral and Social Science ,Mind and Body ,4.1 Discovery and preclinical testing of markers and technologies ,Neurological ,Mental health ,Humans ,Male ,Neurofilament Proteins ,Aged ,Middle Aged ,Independent Living ,Cross-Sectional Studies ,Cognitive Dysfunction ,Neuroimaging ,Cognition ,Biomarkers ,Neuropsychological Tests ,Magnetic Resonance Imaging ,Brain ,White Matter ,Neurofilament light chain ,White matter hyperintensity ,Processing speed ,Neurodegeneration ,Blood-based biomarkers ,Medical and Health Sciences ,Biomedical and clinical sciences ,Health sciences - Abstract
BackgroundPlasma neurofilament light chain (NfL) is a promising biomarker of neurodegeneration with potential clinical utility in monitoring the progression of neurodegenerative diseases. However, the cross-sectional associations of plasma NfL with measures of cognition and brain have been inconsistent in community-dwelling populations.MethodsWe examined these associations in a large community-dwelling sample of early old age men (N = 969, mean age = 67.57 years, range = 61-73 years), who are either cognitively unimpaired (CU) or with mild cognitive impairment (MCI). Specifically, we investigated five cognitive domains (executive function, episodic memory, verbal fluency, processing speed, visual-spatial ability), as well as neuroimaging measures of gray and white matter.ResultsAfter adjusting for age, health status, and young adult general cognitive ability, plasma NfL level was only significantly associated with processing speed and white matter hyperintensity (WMH) volume, but not with other cognitive or neuroimaging measures. The association with processing speed was driven by individuals with MCI, as it was not detected in CU individuals.ConclusionsThese results suggest that in early old age men without dementia, plasma NfL does not appear to be sensitive to cross-sectional individual differences in most domains of cognition or neuroimaging measures of gray and white matter. The revealed plasma NfL associations were limited to WMH for all participants and processing speed only within the MCI cohort. Importantly, considering cognitive status in community-based samples will better inform the interpretation of the relationships of plasma NfL with cognition and brain and may help resolve mixed findings in the literature.
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- 2024
149. Agent orange exposure and prostate cancer risk in the million veteran program
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Pagadala, Meghana S, Lui, Asona J, Zhong, Allison Y, Lynch, Julie A, Karunamuni, Roshan, Lee, Kyung Min, Plym, Anna, Rose, Brent S, Carter, Hannah K, Kibel, Adam S, DuVall, Scott L, Gaziano, J Michael, Panizzon, Matthew S, Hauger, Richard L, and Seibert, Tyler M
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Biomedical and Clinical Sciences ,Clinical Sciences ,Oncology and Carcinogenesis ,Prostate Cancer ,Cancer ,Urologic Diseases ,Humans ,Male ,Agent Orange ,Prostatic Neoplasms ,Veterans ,Middle Aged ,Aged ,Vietnam Conflict ,United States ,Defoliants ,Chemical ,Risk Factors ,2 ,4 ,5-Trichlorophenoxyacetic Acid ,2 ,4-Dichlorophenoxyacetic Acid ,Polychlorinated Dibenzodioxins ,prostate cancer ,MVP ,race/ ethnicity ,health disparities ,Oncology & Carcinogenesis ,Oncology and carcinogenesis - Abstract
BackgroundThe US government considers veterans to have been exposed to Agent Orange if they served in Vietnam while the carcinogen was in use, and these veterans are often deemed at high risk of prostate cancer (PCa). Here, we assess whether presumed Agent Orange exposure is independently associated with increased risk of any metastatic or fatal PCa in a diverse Veteran cohort still alive in the modern era (at least 2011), when accounting for race/ethnicity, family history, and genetic risk.Patients and methodsParticipants in the Million Veteran Program (MVP; enrollment began in 2011) who were on active duty during the Vietnam War era (August 1964-April 1975) were included (n = 301,470). Agent Orange exposure was determined using the US government definition. Genetic risk was assessed via a validated polygenic hazard score. Associations with age at diagnosis of any PCa, metastatic PCa, and death from PCa were assessed via Cox proportional hazards models.Results and interpretationOn univariable analysis, exposure to Agent Orange was not associated with increased PCa (hazard ratio [HR]: 1.02, 95% confidence interval [CI]: 1.00-1.04, p = 0.06), metastatic PCa (HR: 0.98, 95% CI: 0.91-1.05, p = 0.55), or fatal PCa (HR: 0.94, 95% CI: 0.79-1.09, p = 0.41). When accounting for race/ethnicity and family history, Agent Orange exposure was independently associated with slightly increased risk of PCa (HR: 1.06, 95% CI: 1.04-1.09,
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- 2024
150. Predictors of All-Cause 30-Day Readmissions in Patients with Heart Failure at an Urban Safety Net Hospital: The Importance of Social Determinants of Health and Mental Health
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Steverson, Alexandra B, Marano, Paul J, Chen, Caren, Ma, Yifei, Stern, Rachel J, Feng, Jean, Gennatas, Efstathios D, Marks, James D, Durstenfeld, Matthew S, Davis, Jonathan D, Hsue, Priscilla Y, and Zier, Lucas S
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Health Services and Systems ,Biomedical and Clinical Sciences ,Health Sciences ,Behavioral and Social Science ,Cardiovascular ,Social Determinants of Health ,Patient Safety ,Minority Health ,Health Disparities ,Heart Disease ,Generic health relevance ,Good Health and Well Being ,Heart failure ,Readmission ,Safety net hospital ,Social determinants of health ,safety net hospital ,heart failure ,readmission ,social determinants of health - Abstract
IntroductionHeart failure (HF) is a frequent cause of readmissions. Despite caring for underresourced patients and dependence on government funding, safety net hospitals frequently incur penalties for failing to meet pay-for-performance readmission metrics. Limited research exists on the causes of HF readmissions in safety net hospitals. Therefore, we sought to investigate predictors of 30-day all-cause readmission in HF patients in the safety net setting.MethodsWe performed a retrospective chart review of patients admitted for HF from October 2018 to April 2019. We extracted data on demographics and medical comorbidities and performed patient-specific review of social determinants and mental health in 4 domains: race/ethnicity, housing status, substance use, and mental illness. Multivariable Poisson regression modeling was employed to evaluate associations with 30-day all-cause readmission.ResultsThe study population included 290 patients, among whom the mean age was 59 years and 71% (n = 207) were male; 42% (120) were Black/African American (AA), 22% (64) were Hispanic/Latino, and 96% (278) had public insurance; 28% (79) were not housed, 19% (56) had a diagnosis of mental illness, and active substance use was common. The 30-day readmission rate was 25.5% (n = 88). Factors that were associated with increased risk of readmission included self-identifying as Black/AA (relative risk 2.28, 95% confidence interval 1.00-5.20) or Hispanic/Latino (2.53, 1.07-6.00), experiencing homelessness (2.07, 1.21-3.56), living in a shelter (3.20, 1.27-8.02), or intravenous drug use (IVDU) (2.00, 1.08-3.70).ConclusionRace/ethnicity, housing status, and substance use were associated with increased risk of 30-day all-cause readmission in HF patients in a safety net hospital. In contrast to prior studies, medical comorbidities were not associated with increased risk of readmission.
- Published
- 2023
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