851 results on '"Mao Liu"'
Search Results
102. Research on Land-Use Type of Huainan City Based on Flood Risk Perception and Spatial Multi-Criteria Analysis.
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Bo Meng, Mao Liu, Yan Hua Liufu, and Wei Wang
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- 2010
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103. Association of insulin resistance with bone mineral density in a nationwide health check-up population in China
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Ming Zhuo, Ze Chen, Mao-Lin Zhong, Fang Lei, Juan-Juan Qin, Shuhua Liu, Ye-Mao Liu, Tao Sun, Xiao-Jing Zhang, Lihua Zhu, Jingjing Cai, Jun-Ming Ye, and Erping Yang
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Histology ,Physiology ,Endocrinology, Diabetes and Metabolism - Published
- 2023
104. Temperature and rate-dependent plastic deformation mechanism of carbon nanotube fiber: Experiments and modeling
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Deya Wang, Pengfei Wang, Yangfan Wu, Lehu Bu, Jie Tian, Mao Liu, Gengzhi Sun, Lin Mei, and Songlin Xu
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Mechanics of Materials ,Mechanical Engineering ,Condensed Matter Physics - Published
- 2023
105. Exploiting Bursting Oscillations to Improve Energy Capture from Slowly Changing Excitation
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Mao Liu, Wen-An Jiang, Qinsheng Bi, Xindong Ma, Li-Qun Chen, and Yong Wang
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Physics ,Bursting ,Nonlinear system ,Mechanics ,Voltage source ,Restoring force ,Fundamental frequency ,Energy harvesting ,Resonance (particle physics) ,Excitation - Abstract
Energy harvesting has been extensively developed to scavenge energy from mechanical oscillations. Many investigations focus on the resonant issues which can activate large-amplitude responses in the region of the fundamental frequency. Hence, there are many ultra-low slowly changing excitation sources in the actual environment. To adapt to the slowly changing vibrational excitations, in this paper, we explore a novel bursting oscillations to collect energy induced by the low-frequency excitations. The slowly changing ambience excitation is proposed by a cosinoidal voltage source, and the nonlinear restoring force is realized using a nonlinear capacitor. A novel harvester of electromechanical device is developed, the electromechanical coupling equations are presented, and the bursting response is observed via numerical integration. The superiority of the presented bursting energy harvester is contrasted with the resonance and nonresonance frequencies. Based on the method of fast–slow dynamical analysis method, the dynamical mechanism of bursting oscillations is revealed via the transformed phase diagram. Furthermore, the effects of system parameters on the bursting motion are discussed.
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- 2021
106. Impact of micro-environmental factors on survival, reproduction and distribution of Oncomelania hupensis snails
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Mao-Mao Liu, Kun Yang, and Yun Feng
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Oncomelania ,China ,Survival ,030231 tropical medicine ,Snails ,Scoping Review ,Snail ,Distribution ,010502 geochemistry & geophysics ,01 natural sciences ,Schistosoma japonicum ,lcsh:Infectious and parasitic diseases ,03 medical and health sciences ,0302 clinical medicine ,biology.animal ,Animals ,Humans ,lcsh:RC109-216 ,Oncomelania hupensis ,Ecosystem ,0105 earth and related environmental sciences ,biology ,Ecology ,Micro-environment ,Reproduction ,lcsh:Public aspects of medicine ,Public Health, Environmental and Occupational Health ,Intermediate host ,Soil chemistry ,lcsh:RA1-1270 ,General Medicine ,Vegetation ,biology.organism_classification ,Infectious Diseases ,Impact ,Habitat ,Schistosomiasis japonica ,Water quality - Abstract
Background Schistosomiasis japonica is a chronic parasitic disease that seriously harms people's health. Oncomelania hupensis is the only intermediate host of Schistosoma japonicum. The micro-environmental factors surrounding the snail have a great impact on the survival, growth and reproduction of O. hupensis, but there are few relevant systematic analyses until the present. This scoping review aims to identify and summarize the micro-environmental factors that greatly affect O. hupensis, and to find gaps in research thus to provide directions for future in-depth studies. Main body This scoping review searched databases with search terms of the combinations of “Micro(-)environment”, “Oncomelania” and their expanded aspects. A total of 133 original articles were recruited. Predefined data fields were extracted including research methods, influencing factors, and their effects on O. hupensis. Most studies focused on vegetation factors (54.1%), and other factors noted were soil composition (27.8%), water environmental factors (24.1%), and predator (3.0%), respectively. The factors with positive impacts included water level, pH value, soil temperature, soil humidity, the coverage and height of vegetation at suitable levels. This could provide more detailed information for O. hupensis habitat identification and prediction. The factors with negative impacts included plant extracts, snail control and disease prevention forests, and microorganisms with molluscicidal activities. It revealed a potential application as ecological molluscicides in the future. Factors such as physico-chemical properties of water, soil chemistry showed a gap in scientific studies, thus required further extensive research. Conclusions Micro-environmental factors including water quality, soil composition as well as the technology and application of biomolluscicides (plant extracts and microorganisms) deserve more attention. Relative study findings on micro-environment have good potentials in snail control applications. Further studies should be implemented to investigate the impact of micro-environmental factors on snails and close the research gaps.
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- 2021
107. Dynamic changes and clinic significance of serum high mobility group box 1 in patients with total hip arthroplasty.
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Guangfu Zhou, Mao Liu, Xulin Wu, and Bensen Tang
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TOTAL hip replacement ,BIOMARKERS ,PROGNOSIS ,INFLAMMATION ,HEALTH surveys - Abstract
Copyright of Cirugía y Cirujanos is the property of Publicidad Permanyer SLU and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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- 2023
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108. Metabolic dysfunctionassociated fatty liver disease increased the risk of subclinical carotid atherosclerosis in China.
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Fang Lei, Xiao-Ming Wang, Changquan Wang, Xuewei Huang, Ye-Mao Liu, Juan-Juan Qin, Peng Zhang, Yan-Xiao Ji, Zhi-Gang She, Jingjing Cai, Huo-ping Li, Xiao-Jing Zhang, and Hongliang Li
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FATTY liver ,CAROTID intima-media thickness ,ATHEROSCLEROSIS ,POPULATION of China ,YOUNG adults - Abstract
Background and aims: Metabolic dysfunction-associated fatty liver disease (MAFLD) was proposed to substitute NAFLD in 2020. This new term highlights the systematic metabolic disturbances that accompany fatty liver. We evaluated the correlations between MAFLD and subclinical carotid atherosclerosis (SCA) based on a nationwide health examination population in China. Methods: We performed a nationwide cross-sectional population and a Beijing retrospective cohort from 2009 to 2017. SCA was defined as elevated carotid intima-media thickness. The multivariable logistic and Cox models were used to analyze the association between MAFLD and SCA. Results: 153,482 participants were included in the cross-sectional study. MAFLD was significantly associated with SCA in fully adjusted models, with an odds ratio of 1.66; 95% confidence interval (CI): 1.62-1.70. This association was consistent in the cohort, with a hazard ratio (HR) of 1.31. The association between baseline MAFLD and incident SCA increased with hepatic steatosis severity. Subgroup analysis showed an interaction between age and MAFLD, with a higher risk in younger groups (HR:1.67, 95% CI: 1.17-2.40). Conclusion: In this large cross-section and cohort study, MAFLD was significantly associated with the presence and development of SCA. Further, the risk was higher among MAFLD individuals with high hepatic steatosis index and young adults. [ABSTRACT FROM AUTHOR]
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- 2023
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109. Cytochrome CYP2C19 polymorphism and risk of adverse clinical events in clopidogrel-treated patients: A meta-analysis based on 23,035 subjects
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Mao, Liu, Jian, Chen, Changzhi, Liu, Dan, Huang, Suihua, Huang, Wenyi, Tang, and Wei, Wu
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- 2013
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110. The hemodynamics and blood trauma in axial blood pump under different operating models
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Yunpeng Zhang, Xiangyu Wu, Yiming Wang, Hongtao Liu, and Guang‐Mao Liu
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Biomaterials ,Heart Failure ,Biomedical Engineering ,Hemodynamics ,Hydrodynamics ,Models, Cardiovascular ,Medicine (miscellaneous) ,Animals ,Bioengineering ,Computer Simulation ,General Medicine ,Heart-Assist Devices ,Hemolysis - Abstract
Speed modulation of blood pumps has been proved to help restore vascular pulsatility and implemented clinically during treatment for cardiac failure. However, its effect on blood trauma has not been studied thoroughly.In this paper, we study the flow field of an axial pump FW-X under the modes of co-pulse, counter pulse, and constant speed to evaluate the blood trauma. Based on the coupling model of cardiovascular systems and axial blood pump, aortic pressure and the pump flow were obtained and applied as the boundary conditions at the pump outlet and inlet. The level of shear stress and hemolysis index were derived from computational fluid dynamics (CFD) simulation.Results showed that the constant speed mode had the lowest shear stress level and hemolytic index at the expense of diminished pulsatility. Compared with the constant speed mode, the hemolysis index of co-pulse and counter pulse mode was higher, but it was helpful to restore vascular pulsatility.This method can be easily incorporated in the in vitro testing phase to analyze and decrease a pump's trauma before animal experimentation, thereby reducing the cost of blood pump development.
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- 2022
111. Distributions and trends of the global burden of COPD attributable to risk factors by SDI, age, and sex from 1990 to 2019: a systematic analysis of GBD 2019 data
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Jiahua Zou, Tao Sun, Xiaohui Song, Ye-Mao Liu, Fang Lei, Ming-Ming Chen, Ze Chen, Peng Zhang, Yan-Xiao Ji, Xiao-Jing Zhang, Zhi-Gang She, Jingjing Cai, Yunman Luo, Ping Wang, and Hongliang Li
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Male ,Pulmonary Disease, Chronic Obstructive ,Ozone ,Risk Factors ,Humans ,Female ,Particulate Matter ,Quality-Adjusted Life Years ,Global Health ,Global Burden of Disease - Abstract
Background Global distributions and trends of the risk-attributable burdens of chronic obstructive pulmonary disease (COPD) have rarely been systematically explored. To guide the formulation of targeted and accurate strategies for the management of COPD, we analyzed COPD burdens attributable to known risk factors. Methods Using detailed COPD data from the Global Burden of Disease study 2019, we analyzed disability-adjusted life years (DALYs), years lived with disability (YLDs), years of life lost (YLLs), and deaths attributable to each risk factor from 1990 to 2019. Additionally, we calculated estimated annual percentage changes (EAPCs) during the study period. The population attributable fraction (PAF) and summary exposure value (SEV) of each risk factor are also presented. Results From 1990 to 2019, the age-standardized DALY and death rates of COPD attributable to smoking and household air pollution, occupational particles, secondhand smoke, and low temperature presented consistently declining trends in almost all socio-demographic index (SDI) regions. However, the decline in YLD was not as dramatic as that of the death rate. In contrast, the COPD burden attributable to ambient particulate matter, ozone, and high temperature exposure showed undesirable increasing trends in the low- and low-middle-SDI regions. In addition, the age-standardized DALY and death rates attributable to each risk factor except household air pollution and low temperature were the highest in the low-middle-SDI region. In 2019, the COPD burden attributable to smoking ambient particulate matter, ozone, occupational particles, low and high temperature was obviously greater in males than in females. Meanwhile, the most important risk factors for female varied across regions (low- and low-middle-SDI regions: household air pollution; middle-SDI region: ambient particles; high-middle- and high-SDI region: smoking). Conclusions Increasing trends of COPD burden attributable to ambient particulate matter, ozone, and high temperature exposure in the low-middle- and low-SDI regions call for an urgent need to implement specific and effective measures. Moreover, considering the gender differences in COPD burdens attributable to some risk factors such as ambient particulate matter and ozone with similar SEV, further research on biological differences between sexes in COPD and relevant policy-making of disease prevention are required.
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- 2022
112. Does vitamin D improve symptomatic and structural outcomes in knee osteoarthritis? A systematic review and meta-analysis
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Xiao Luo, Lihui Peng, Chengsong He, Yue He, Jie Chen, Mao Liu, and Zixia Zhao
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Aging ,medicine.medical_specialty ,WOMAC ,business.industry ,Subgroup analysis ,Osteoarthritis ,medicine.disease ,Confidence interval ,03 medical and health sciences ,0302 clinical medicine ,Strictly standardized mean difference ,Statistical significance ,Meta-analysis ,Internal medicine ,Vitamin D and neurology ,Medicine ,030212 general & internal medicine ,Geriatrics and Gerontology ,business ,030217 neurology & neurosurgery - Abstract
To provide evidence on the effects of vitamin D supplementation on knee osteoarthritis (KOA) and new targets for clinical prevention and treatment of KOA. The PubMed, Embase, Web of science, Wanfang, CNKI and SinoMed databases were retrieved to investigate the effects of vitamin D supplementation on patients with KOA. The search time was from databases establishment to 15 November 2020. RevMan5.3 software was used for meta-analysis. The results were expressed as standardized mean difference (SMD) with 95% confidence interval (CI) or weighted mean difference (WMD) with 95% confidence interval (CI). A total of 1599 patients with osteoarthritis of the knee were included in the study, which involved six articles. The results of the meta-analysis showed that vitamin D supplementation is statistically significant for WOMAC score (SMD = − 0.67, 95% CI − 1.23 to − 0.12) in patients with KOA, including WOMAC pain score (SMD = − 0.32, 95% CI − 0.63 to − 0.02), function score (SMD = − 0.34, 95% CI − 0.60 to − 0.08) and stiffness score (SMD = − 0.13, 95% CI − 0.26 to − 0.01). In subgroup analysis, vitamin D supplementation less than 2000 IU was statistically significant for the reduction of stiffness score (SMD = − 0.22, 95% CI − 0.40 to − 0.04). Vitamin D supplements can reduce synovial fluid volume progression in patients with KOA (SMD = − 0.20, 95% CI − 0.39 to − 0.02). There was no statistical significance in improving tibia cartilage volume (SMD = 0.12, 95% CI − 0.05 to 0.29), joint space width (SMD = − 0.10, 95% CI − 0.26 to 0.05) and bone marrow lesions (SMD = 0.03, 95% CI − 0.26 to 0.31). Vitamin D supplements can improve WOMAC pain and function in patients with KOA. But there is a lack of strong evidence that vitamin D supplementation can prevent structural progression in patients with KOA.
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- 2021
113. Trechispora daweishanensis and T. xantha spp. nov. (Hydnodontaceae, Trechisporales) found in Yunnan Province of China
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Tong-Kai Zong, Chao-Mao Liu, Jian-Rong Wu, and Chang-Lin Zhao
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Trechispora ,biology ,Hypha ,Phylogenetic tree ,Phylogenetics ,Botany ,Basidiocarp ,Key (lock) ,Hymenophore ,Taxonomy (biology) ,Plant Science ,biology.organism_classification ,Ecology, Evolution, Behavior and Systematics - Abstract
Two wood-inhabiting fungal species, Trechispora daweishanensis and T. xantha spp. nov. are proposed based on morphological features and molecular evidence. Trechispora daweishanensis is characterized by basidiomata with an annual growth habit, a tuberculate hymenophore, a monomitic hyphal system with clamped generative hyphae and ellipsoid, hyaline, thin-walled, smooth basidiospores measuring 3.8–5 × 2.7–3.5 µm. Trechispora xantha is characterized by resupinate, cracked basidiomata with a buff-coloured hymenial surface, a monomitic hyphal system and ellipsoid, hyaline, thin-walled, smooth basidiospores measuring 4.3–5.7 × 3.2–4 µm. Sequences of ITS and nLSU gene regions of the studied samples were generated. The phylogenetic analysis based on molecular data of ITS+nLSU sequences supported the novelty of these two species. Furthermore, we provide a key to the known species of Trechispora in China.
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- 2021
114. Cardiovascular fingolimod effects on rapid baroreceptor unloading are counterbalanced by baroreflex resetting
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Katharina Hoesl, Mao Liu, Francesca Canavese, Ruihao Wang, Klemens Winder, De-Hyung Lee, Carmen de Rojas Leal, Max J. Hilz, Ralf A. Linker, and Sankanika Roy
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medicine.medical_specialty ,Baroreceptor ,Cardiovascular fingolimod effects ,Valsalva Maneuver ,medicine.medical_treatment ,Diastole ,Blood Pressure ,Pressoreceptors ,Dermatology ,030204 cardiovascular system & hematology ,Baroreflex ,Multiple sclerosis ,03 medical and health sciences ,0302 clinical medicine ,Heart Rate ,Internal medicine ,Heart rate ,Valsalva maneuver ,Humans ,Medicine ,ddc:610 ,Baroreflex gain ,Fingolimod Hydrochloride ,business.industry ,General Medicine ,Fingolimod ,Psychiatry and Mental health ,Blood pressure ,Cardiology ,Original Article ,Baroreflex resetting ,Neurology (clinical) ,Analysis of variance ,business ,030217 neurology & neurosurgery ,circulatory and respiratory physiology ,medicine.drug - Abstract
Background and purpose Initial cardiovascular fingolimod effects might compromise baroreflex responses to rapid blood pressure (BP) changes during common Valsalva-like maneuvers. This study evaluated cardiovascular responses to Valsalva maneuver (VM)-induced baroreceptor unloading and loading upon fingolimod initiation. Patients and methods Twenty-one patients with relapsing-remitting multiple sclerosis performed VMs before and 0.5, 1, 2, 3, 4, 5, and 6 hours after fingolimod initiation. We recorded heart rate (HR) as RR intervals (RRI), systolic and diastolic BP (BPsys, BPdia) during VM phase 1, VM phase 2 early, VM phase 2 late, and VM phase 4. Using linear regression analysis between decreasing BPsys and RRI values during VM phase 2 early, we determined baroreflex gain (BRG) reflecting vagal withdrawal and sympathetic activation upon baroreceptor unloading. To assess cardiovagal activation upon baroreceptor loading, we calculated Valsalva ratios (VR) between maximal and minimal RRIs after strain release. Analysis of variance or Friedman tests with post hoc analysis compared corresponding parameters at the eight time points (significance: p Results RRIs at VM phase 1, VM phase 2 early, and VM phase 2 late were higher after than before fingolimod initiation, and maximal after 4 hours. Fingolimod did not affect the longest RRIs upon strain release, but after 3, 5, and 6 hours lowered the highest BPsys values during overshoot and all BPdia values, and thus reduced VRs. BRG was slightly higher after 3 and 5 hours, and significantly higher after 4 hours than before fingolimod initiation. Conclusions VR-decreases 3–6 hours after fingolimod initiation are physiologic results of fingolimod-associated attenuations of BP and HR increases at the end of strain and do not suggest impaired cardiovagal activation upon baroreceptor loading. Stable and at the time of HR nadir significantly increased BRGs indicate improved responses to baroreceptor unloading. Thus, cardiovascular fingolimod effects do not impair autonomic responses to sudden baroreceptor loading or unloading but seem to be mitigated by baroreflex resetting.
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- 2021
115. Oblique penetration mechanism of hybrid composite laminates
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Xindong Ma, Wenan Jiang, Meng Han, Qinsheng Bi, Vadim V. Silberschmidt, Mao Liu, and Chuwei Zhou
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Materials science ,Oblique case ,dissipation energy ,Penetration (firestop) ,Composite laminates ,Mechanism (engineering) ,oblique penetration ,hybrid composite ,TA401-492 ,Materials Chemistry ,Ceramics and Composites ,Composite material ,contact force ,Materials of engineering and construction. Mechanics of materials - Abstract
Hybrid fiber composites are widely used to improve the anti-penetration performance. Carbon/Kevlar hybrid composites are used in aircrafts and safety devices, thanks to the strong toughness of Kevlar fibers and high strength of carbon fibers. In the present work, the contact force of hybrid composites under oblique impact is derived. The viscoelastic constitutive model of Kevlar layer is investigated and the dissipation energies of composites for different high velocity oblique impacts are simulated. The results show that hybrid composites have good bullet-proof performance, the contact forces are fluctuant in short time and the frictional dissipation energy allows us to prevent penetration.
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- 2021
116. Supramolecular electrocatalysis of a highly efficient oxygen evolution reaction with cucurbit[6]uril
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Qing-Mei Ge, Mao Liu, Zhu Tao, Nan Jiang, Dai Xin, Jie Zhao, Xian-Yi Jin, and Hang Cong
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Tafel equation ,Chemistry ,Oxygen evolution ,General Chemistry ,Overpotential ,Polypyrrole ,Electrocatalyst ,Catalysis ,Dielectric spectroscopy ,chemistry.chemical_compound ,Chemical engineering ,Linear sweep voltammetry ,Materials Chemistry ,Water splitting - Abstract
A supramolecular strategy was developed for electrocatalytic water splitting in the presence of a macrocyclic compound. The improvement in the oxygen evolution reaction (OER) was observed on the surface of an electrode modified via the facile layer-by-layer assembly of polypyrrole (PPy), reduced graphene oxide (rGO) and cucurbit[6]uril (Q[6]) in sequence. The electrochemical performance was evaluated, and the results indicate the remarkable activity of the proposed supramolecular electrocatalyst toward the OER in alkaline media. The morphology and chemical structure of the electrocatalyst were estimated before and after the OER process. Linear sweep voltammetry measurements suggested that a current density of 10 mA cm−2 at an overpotential of 377 mV was achieved, which is very close to the value of IrO2 under the same conditions, and the calculated Tafel slope of 167 mV dec−1 and electrochemical impedance spectroscopy results imply that a fast charge transfer occurs on the electrode with the functionalization of Q[6]. The developed catalyst could be considered as a potential alternative material for high-efficiency electrocatalytic OER.
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- 2021
117. Comparative analysis of the clinical effect and safety of Laparoscopic Radical Cystectomy + Orthotopic Ileal Neobladder and Open Surgery
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Yuanhua Liu, Hai-Tao Dai, Jiang Zheng, and Chang-Mao Liu
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Laparoscopic surgery ,medicine.medical_specialty ,Ileus ,Urinary system ,medicine.medical_treatment ,media_common.quotation_subject ,030232 urology & nephrology ,Cystectomy ,Urination ,03 medical and health sciences ,0302 clinical medicine ,Bladder tumor ,Medicine ,Dysuria ,media_common ,Urinary continence ,business.industry ,General Medicine ,Perioperative ,Adverse reaction ,medicine.disease ,Surgery ,Curative effect ,030220 oncology & carcinogenesis ,Orthotopic ileal neobladder ,Original Article ,medicine.symptom ,business - Abstract
Objectives: To explore the clinical effect and safety of laparoscopic radical cystectomy + orthotopic ileal neobladder and open surgery. Methods: The study was conducted at Jingzhou First People’s Hospital from January 2017 to July 2018. In this study 87 patients undergoing radical cystectomy + orthotopic ileal neobladder were chosen and classified into an observation group (48 cases) and a control group (39 cases) according to the surgical methods. The observation group underwent laparoscopic surgery, while the control group underwent open surgery. Perioperative period and prognostic conditions were compared in both groups. Results: The intraoperative bleeding amount obviously decreased. The recovery time of gastroenteric function and postoperative hospitalization time were significantly shortened. Postoperative pain was significantly alleviated. Compared with the control group, the observation group showed significant differences (P0.05). The differences in both groups in terms of the daytime/nighttime urinary continence rate, maximum urinary flow rate, internal bladder pressure, maximum bladder pressure during urination, internal urethral pressure, bladder capacity, and residual urine volume six months after the operation were not statistically significant (P>0.05). There was no significant difference in postoperative complications, including urinary fistula, bleeding, urinary tract infection, pulmonary infection, dysuria, lymphatic leakage, ureterostenosis, or relapse (P>0.05). The ileus incidence rate in the observation group was obviously lower than that in the control group, and the difference was statistically significant (P
- Published
- 2021
118. Threat identification model for suspected Internet of Things attack groups
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Rui, Yu, primary, Fu, Chen, additional, Wen-mao, Liu, additional, and Hong-qing, Sang, additional
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- 2022
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119. Guide and control of thermal conduction with isotropic thermodynamic parameters based on a rotary-concentrating device
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Mao Liu and Quan Yan
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General Physics and Astronomy - Abstract
A rotary-concentrating device for thermal conduction is constructed to control and guide thermal energy transmitting in elastic plates. The designed device has the ability of concentrating for thermal conduction and controlling the processes of thermal diffusion in a plate. The multilayered isotropic material properties of the rotary-concentrating device are derived based on the transformation and rotary medium method and a rotation parameter to control the thermal diffusion process is introduced. The efficiency of the rotary-concentrating device for thermal conduction is verified. Stability of temperature fields in a plate with the rotary-concentrating device is analyzed to study the performance of rotary-concentrating. Numerical examples show that the constructed rotary-concentrating device for thermal conduction can effectively rotate and focus on the thermal energy into the device for a wide range of diffusion temperatures, which can enhance the thermal conduction. Therefore, this study can provide a theoretical support for potential applications in fields of energy harvesting and thermal conduction control.
- Published
- 2023
120. Efficacy of laparoscopic inguinal hernia in day surgery mode and inpatient surgery mode in China: A meta-analysis
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Yang Zhong, Miao He, Zhi Liu, Jian Yu Chen, Xiao Jiang Lv, Mao Liu, Ai Ping Wen, Long Qin, and Jian Shui Li
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General Medicine - Published
- 2023
121. Gut microbiota links with cognitive impairment in amyotrophic lateral sclerosis: A multi-omics study
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Zhenxiang Gong, Li Ba, Jiahui Tang, Yuan Yang, Zehui Li, Mao Liu, Chun Yang, Fengfei Ding, and Min Zhang
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General Medicine ,General Biochemistry, Genetics and Molecular Biology - Published
- 2023
122. Absorption of SO2 by deep eutectic solvents composed of EmimCl and dihydric alcohols: Thermodynamic and absorption mechanism studies
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Mao Liu, Tianxiang Zhao, Huinan Dong, Yun Xu, and Chun Zhu
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Materials Chemistry ,Physical and Theoretical Chemistry ,Condensed Matter Physics ,Spectroscopy ,Atomic and Molecular Physics, and Optics ,Electronic, Optical and Magnetic Materials - Published
- 2023
123. Energy-saving-lamp-driven photodegradation of pyroquilon and admire in the presence of cucurbituril-block composite of g-C3N4/Ag3PO4@Q[7]
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Zheng-Kun Bai, Qing-Mei Ge, Nan Jiang, Hang Cong, Zhu Tao, Mao Liu, and Ying Fan
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Inorganic Chemistry ,Organic Chemistry ,Electrical and Electronic Engineering ,Physical and Theoretical Chemistry ,Atomic and Molecular Physics, and Optics ,Spectroscopy ,Electronic, Optical and Magnetic Materials - Published
- 2023
124. Assessment of emergency response policy based on Markov process.
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Yafei Zhou and Mao Liu
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- 2013
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125. A two-phase flow approach for modeling blood stasis and estimating the thrombosis potential of a ventricular assist device
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Wei-Feng Dai, Peng Wu, and Guang-Mao Liu
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medicine.medical_specialty ,medicine.medical_treatment ,0206 medical engineering ,Biomedical Engineering ,Medicine (miscellaneous) ,Hemodynamics ,Bioengineering ,02 engineering and technology ,Blood stasis ,030204 cardiovascular system & hematology ,Biomaterials ,03 medical and health sciences ,0302 clinical medicine ,Internal medicine ,Humans ,Medicine ,Computer Simulation ,business.industry ,Models, Cardiovascular ,Thrombosis ,General Medicine ,medicine.disease ,020601 biomedical engineering ,Economic benefits ,Blood pump ,Key factors ,Ventricular assist device ,Cardiology ,Heart-Assist Devices ,Stress, Mechanical ,business ,Blood Flow Velocity - Abstract
Thrombosis and its related events have become a major concern during the development and optimization of ventricular assist devices (VADs, also called blood pumps), and limit their clinical use and economic benefits. Attempts have been made to model the thrombosis formation, considering hemodynamic and biochemical processes. However, the complexities and computational expenses are prohibitive. Blood stasis is one of the key factors which may lead to the formation of thrombosis and excessive thromboembolic risks for patients. This study proposed a novel approach for modeling blood stasis, based on a two-phase flow principle. The locations of blood residual can be tracked over time, so that regions of blood stasis can be identified. The blood stasis in an axial blood pump is simulated under various working conditions, the results agree well with the experimental results. In contrast, conventional hemodynamic metrics such as velocity, time-averaged wall shear stress (TAWSS), and relative residence time (RRT), were contradictory in judging risk of blood stasis and thrombosis, and inconsistent with experimental results. We also found that the pump operating at the designed rotational speed is less prone to blood stasis. The model provides an efficient and fast alternative for evaluating blood stasis and thrombosis potential in blood pumps, and will be a valuable addition to the tools to support the design and improvement of VADs.
- Published
- 2020
126. No significant association between dipeptidyl peptidase-4 inhibitors and adverse outcomes of COVID-19
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Hongliang Li, Zhi-Gang She, Haomiao Li, Jingjing Cai, Lihua Zhu, Ye-Mao Liu, Xiao-Jing Zhang, Wenxin Wang, Fang Lei, Xu Cheng, Jianghua Zhou, Bin Wu, Juan-Juan Qin, Feng Zhou, Xin Zhang, and Juan Yang
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endocrine system ,2019-20 coronavirus outbreak ,endocrine system diseases ,Glucose control ,Coronavirus disease 2019 (COVID-19) ,Adverse outcomes ,Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) ,Observational Study ,digestive system ,03 medical and health sciences ,0302 clinical medicine ,Diabetes mellitus ,Medicine ,Adverse effect ,Dipeptidyl peptidase-4 ,business.industry ,SARS-CoV-2 ,Adverse effects ,digestive, oral, and skin physiology ,Diabetes ,nutritional and metabolic diseases ,COVID-19 ,General Medicine ,medicine.disease ,030220 oncology & carcinogenesis ,Immunology ,030211 gastroenterology & hepatology ,business ,DPP4 inhibitors - Abstract
BACKGROUND Dipeptidyl peptidase-4 (DPP4) is commonly targeted to achieve glycemic control and has potent anti-inflammatory and immunoregulatory effects. Recent structural analyses indicated a potential tight interaction between DPP4 and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), raising a promising hypothesis that DPP4 inhibitor (DPP4i) drugs might be an optimal strategy for treating coronavirus disease 2019 (COVID-19) among patients with diabetes. However, there has been no direct clinical evidence illuminating the associations between DPP4i use and COVID-19 outcomes. AIM To illuminate the associations between DPP4i usage and the adverse outcomes of COVID-19. METHODS We conducted a multicenter, retrospective analysis including 2563 patients with type 2 diabetes who were hospitalized due to COVID-19 at 16 hospitals in Hubei Province, China. After excluding ineligible individuals, 142 patients who received DPP4i drugs and 1115 patients who received non-DPP4i oral anti-diabetic drugs were included in the subsequent analysis. We performed a strict propensity score matching (PSM) analysis where age, sex, comorbidities, number of oral hypoglycemic agents, heart rate, blood pressure, pulse oxygen saturation (SpO2) < 95%, CT diagnosed bilateral lung lesions, laboratory indicators, and proportion of insulin usage were matched. Finally, 111 participants treated with DPP4i drugs were successfully matched to 333 non-DPP4i users. Then, a linear logistic model and mixed-effect Cox model were applied to analyze the associations between in-hospital DPP4i use and adverse outcomes of COVID-19. RESULTS After rigorous matching and further adjustments for imbalanced variables in the linear logistic model and Cox adjusted model, we found that there was no significant association between in-hospital DPP4i use (DPP4i group) and 28-d all-cause mortality (adjusted hazard ratio = 0.44, 95%CI: 0.09-2.11, P = 0.31). Likewise, the incidences and risks of secondary outcomes, including septic shock, acute respiratory distress syndrome, or acute organ (kidney, liver, and cardiac) injuries, were also comparable between the DPP4i and non-DPP4i groups. The performance of DPP4i agents in achieving glucose control (e.g., the median level of fasting blood glucose and random blood glucose) and inflammatory regulation was approximately equivalent in the DPP4i and non-DPP4i groups. Furthermore, we did not observe substantial side effects such as uncontrolled glycemia or acidosis due to DPP4i application relative to the use of non-DPP4i agents in the study cohort. CONCLUSION Our findings demonstrated that DPP4i use is not significantly associated with poor outcomes of COVID-19 or other adverse effects of anti-diabetic treatment. The data support the continuation of DPP4i agents for diabetes management in the setting of COVID-19.
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- 2020
127. Nanostructured pyramidal black silicon with ultra-low reflectance and high passivation
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Shih-Mao Liu, Wan-Yu Wu, Yun-Shao Cho, Chia-Hsun Hsu, Wen-Zhang Zhu, Pao-Hsun Huang, Shui-Yang Lien, and Chien-Jung Huang
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Nanostructure ,Passivation ,General Chemical Engineering ,Nanowire ,02 engineering and technology ,Reflectance ,010402 general chemistry ,01 natural sciences ,law.invention ,lcsh:Chemistry ,chemistry.chemical_compound ,law ,Solar cell ,business.industry ,Chemistry ,Energy conversion efficiency ,Black silicon ,Metal assisted chemical etching ,General Chemistry ,021001 nanoscience & nanotechnology ,Isotropic etching ,0104 chemical sciences ,Silicon nitride ,lcsh:QD1-999 ,Optoelectronics ,0210 nano-technology ,business - Abstract
In this study, nanostructured pyramidal black silicon is prepared by metal assisted chemical etching method, in which the silver nitrate (AgNO3) is used as the metal catalyst. Effects of the concentration of AgNO3 on passivation and optical properties of the black silicon are investigated. The experimental results show that at the AgNO3 concentration of 0.03 M, the nanostructure length is about 300 nm, and the reflectance of the black silicon with a stack of silicon nitride (SiNx) and aluminum oxide (Al2O3) is 0.8%, which is comparable to that of the conventional black silicon with micrometer-long nanowires. In addition, an acceptably low surface recombination rate of 42 cm/s can be obtained. Plasma chemical vapor deposited SiNx is deposited well on the top of nanostructures of black silicon, but shows poor coverage at the bottom region. Spatial atomic layer deposited Al2O3 can conformally cover the nanostructures with high passivation quality. Simulation result indicates an improvement of 5.5% of conversion efficiency for the nanostructured pyramidal black silicon solar cell compared to industrial silicon solar cell. The short nanostructured pyramidal surface with low reflectance and high passivation is expected to be helpful for black silicon technology applied to photovoltaic applications.
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- 2020
128. Reactive modified curcumin for high-fastness nonaqueous SC-CO2 dyeing of cotton fabric
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Zhao Hongjuan, Mingyue Wang, Laijiu Zheng, Mao Liu, and Xiaoqing Xiong
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chemistry.chemical_classification ,Supercritical carbon dioxide ,Polymers and Plastics ,Low toxicity ,technology, industry, and agriculture ,Ether ,02 engineering and technology ,010402 general chemistry ,021001 nanoscience & nanotechnology ,01 natural sciences ,0104 chemical sciences ,chemistry.chemical_compound ,Adsorption ,chemistry ,Chemical engineering ,parasitic diseases ,Curcumin ,Dyeing ,Solubility ,0210 nano-technology ,Alkyl - Abstract
Modified curcumin, which has the advantages of low toxicity, high solubility, and little color change after modification, is very suitable for nonaqueous supercritical carbon dioxide cotton dyeing. However, the existing curcumin modification technology focuses on improving its solubility. Modified curcumin is directly adsorbed onto cotton fabrics, and the main interaction forces are van der Waals forces, which causes the poor fastness of modified curcumin to dyed cotton fabrics. In this study, reactive groups (hydroxyalkyls) were introduced into curcumin to enhance its fastness to cotton fabrics. The results showed that, similar to alkyl groups, hydroxyalkyl groups can enhance the color depth of dyed cotton fabrics by elevating the solubility of modified curcumin in supercritical carbon dioxide. The higher the solubility of modified curcumin in supercritical carbon dioxide was, the higher the K/S value of the dyed cotton fabric. Furthermore, the hydroxyl groups on the modified curcumin could form ether bonds with the hydroxyl groups on cotton fabrics. Therefore, the washing and rubbing fastness of hydroxyalkyl-curcumin-dyed cotton fabric was better than that of alkyl-curcumin-dyed cotton fabric.
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- 2020
129. A 3‐dimensional‐printed left ventricle model incorporated into a mock circulatory loop to investigate hemodynamics inside a severely failing ventricle supported by a blood pump
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Shengshou Hu, Jian-Feng Hou, Run-Jie Wei, and Guang-Mao Liu
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Models, Anatomic ,medicine.medical_specialty ,Heart Ventricles ,0206 medical engineering ,Biomedical Engineering ,Medicine (miscellaneous) ,Hemodynamics ,Aorta, Thoracic ,Bioengineering ,02 engineering and technology ,Blood stasis ,030204 cardiovascular system & hematology ,Severity of Illness Index ,Biomaterials ,03 medical and health sciences ,0302 clinical medicine ,Internal medicine ,medicine ,Humans ,Heart Failure ,business.industry ,Models, Cardiovascular ,Equipment Design ,General Medicine ,Blood flow ,medicine.disease ,020601 biomedical engineering ,Thrombosis ,Blood pump ,medicine.anatomical_structure ,Ventricle ,Heart failure ,Printing, Three-Dimensional ,Circulatory system ,Cardiology ,Heart-Assist Devices ,Tomography, X-Ray Computed ,business - Abstract
Intraventricular blood stasis is a design consideration for continuous flow blood pumps and might contribute to adverse events such as thrombosis and ventricular suction. However, the blood flow inside left ventricles (LVs) supported by blood pumps is still unclear. In vitro experiments were conducted to imitate how the hydraulic performance of an axial blood pump affects the intraventricular blood flow of a severe heart failure patient, such as velocity distribution, vorticity, and standard deviation of velocity. In this study, a silicone model of the LV was constructed from the computed tomography data of one patient with heart failure and was 3D printed. Then, intraventricular flow was visualized by particle image velocimetry equipment within a mock circulation loop. The results showed that the axial blood pump suctions most of the blood in a severely failing LV, there was an altered flow status within the LV, and blood stasis appeared in the central region of the LV. Some blood may be suctioned from the aortic valve to the blood pump because the patient's native heart was severely failing. Blood stasis at the LV center may cause thrombosis in the LV. The vortex flow near the inner wall of the LV can thoroughly wash the left ventricular cavity.
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- 2020
130. A Bidirectional Relationship Between Hyperuricemia and Metabolic Dysfunction-Associated Fatty Liver Disease
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Chengzhang Yang, Qianjin He, Ze Chen, Juan-Juan Qin, Fang Lei, Ye-Mao Liu, Weifang Liu, Ming-Ming Chen, Tao Sun, Qian Zhu, Yonglin Wu, Ming Zhuo, Jingjing Cai, Weiming Mao, and Hongliang Li
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nonalcoholic fatty liver disease ,Endocrinology, Diabetes and Metabolism ,nutritional and metabolic diseases ,Hyperuricemia ,cross-lagged path analysis ,RC648-665 ,Diseases of the endocrine glands. Clinical endocrinology ,Cross-Sectional Studies ,Non-alcoholic Fatty Liver Disease ,metabolic dysfunction-associated fatty liver disease ,Prevalence ,Humans ,Longitudinal Studies ,metabolism ,Retrospective Studies - Abstract
Background and aimsMetabolic dysfunction-associated fatty liver disease (MAFLD) is a newly emerged term that is suggested to better reflect the pathogenesis of nonalcoholic fatty liver disease (NAFLD); however, the association between hyperuricemia and MAFLD has not been explored in the Chinese population. Meantime, this study also examined the temporal relationship between the two entities in a longitudinal cohort.MethodsWe conducted a retrospective cross-sectional study including 1,587,962 individuals from 19 health check-up centers in China from 2009-2017 and a longitudinal study with 16,112 individuals. A logistic regression model was applied to determine the association between hyperuricemia and MAFLD in a cross-sectional study. The Cox regression model was used to explore the association between hyperuricemia at baseline and subsequent onset of MAFLD or the association between the presence of MAFLD at baseline and the subsequent incidence of hyperuricemia. The cross-lagged analysis was applied to exam the temporal relationship between hyperuricemia and MAFLD.ResultsIn the cross-sectional study, hyperuricemia showed a strong positive association with MAFLD after controlled potential confounders. In the longitudinal cohorts, hyperuricemia at baseline was associated with the new-onset of MAFLD, with a hazard ratio (HR) of 1.765 (95% CI: 1.512, 2.060). Interestingly, baseline MAFLD was also associated with the subsequent incidence of hyperuricemia, with an HR of 1.245 (95% CI: 1.106, 1.400). The cross-lagged path analysis revealed a bidirectional relationship between hyperuricemia and MAFLD.ConclusionsThe results suggested that hyperuricemia and MAFLD form a vicious cycle, resulting in more deterioration of metabolic status.
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- 2022
131. High Remnant Cholesterol Level Potentiates the Development of Hypertension
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Ming-Ming Chen, Xuewei Huang, Chengsheng Xu, Xiao-Hui Song, Ye-Mao Liu, Dongai Yao, Huiming Lu, Gang Wang, Gui-Lan Zhang, Ze Chen, Tao Sun, Chengzhang Yang, Fang Lei, Juan-Juan Qin, Yan-Xiao Ji, Peng Zhang, Xiao-Jing Zhang, Lihua Zhu, Jingjing Cai, Feng Wan, Zhi-Gang She, and Hongliang Li
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Adult ,Male ,systolic blood pressure ,hypertension ,Lipoproteins ,Endocrinology, Diabetes and Metabolism ,diastolic blood pressure ,Blood Pressure ,retrospective cohort ,Middle Aged ,RC648-665 ,Diseases of the endocrine glands. Clinical endocrinology ,remnant cholesterol ,Cholesterol ,Cross-Sectional Studies ,Humans ,Female ,Longitudinal Studies ,Triglycerides ,Retrospective Studies - Abstract
BackgroundEmerging evidence suggests an association between remnant cholesterol (RC) and vascular damage and hypertension. However, this association has not been explored in a large-scale population in China, and a temporal relationship between RC and hypertension also needs to be investigated.MethodsWe conducted a retrospective cross-sectional study in 2,199,366 individuals and a longitudinal study in 24,252 individuals with repeated measurements of lipid profile and blood pressure in at least a 3-year follow-up. The logistic model was used to explore the association between lipid components and hypertension in the cross-sectional analysis. The Cox model was used to analyze the association between high RC (HRC) at baseline and the subsequent incidence of hypertension or the association between hypertension at baseline and incidence of HRC. The cross-lagged panel model was applied to analyze the temporal relationship between RC and hypertension.ResultsRC level as a continuous variable had the highest correlation with hypertension among lipid profiles, including RC, low-density lipoprotein cholesterol, total cholesterol, non-high-density lipoprotein cholesterol, and triglycerides, with an odds ratio of 1.59 (95% confidence interval: 1.58–1.59). In the longitudinal cohort, HRC at baseline was associated with incident hypertension. We further explored the temporal relationship between RC and hypertension using the cross-lagged analysis, and the results showed that RC increase preceded the development of hypertension, rather than vice versa.ConclusionsRC had an unexpected high correlation with the prevalence and incidence of hypertension. Moreover, RC increase might precede the development of hypertension, suggesting the potential role of RC in the development of hypertension.
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- 2022
132. New avenues for NASH therapy by targeting ACC
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Huijie Bian, Ye-Mao Liu, and Zhi-Nan Chen
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Metabolic Diseases ,Physiology ,Non-alcoholic Fatty Liver Disease ,Humans ,Cell Biology ,Enzyme Inhibitors ,Molecular Biology ,Acetyl-CoA Carboxylase - Abstract
Acetyl-CoA carboxylase (ACC) is one of the more promising therapeutic targets for non-alcoholic steatohepatitis (NASH), but current ACC inhibitors already tested in clinical trials also exert the unwanted adverse side effect of hypertriglyceridemia. In two recent studies by Calle et al. in Nature Medicine and Zhang et al. in Science Translational Medicine, new strategies for ACC targeting were explored for NASH therapy that successfully resolved the adverse effect of hyperlipidemia while maintaining potent anti-NASH efficacy. These findings bring encouraging new momentum to the clinical application of ACC inhibition for NASH therapy.
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- 2022
133. Cucurbit[7]uril‐Catalyzed Controllable Pinacol Rearrangement with Activated Hydride Migration
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Ye Jin, Min Li, Mao Liu, Qingmei Ge, Hang Cong, and Zhu Tao
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Organic Chemistry ,Physical and Theoretical Chemistry - Published
- 2022
134. Toughening Mechanisms for the Dyna Mic Perforation Behavior of Laminar Aluminum Alloy with Lubricated Frictional Interfaces
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Pengfei Wang, Hebin Jiang, Mao Liu, Liang Zhang, and Songlin Xu
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Mechanics of Materials ,Mechanical Engineering ,General Materials Science - Published
- 2022
135. Effect of Bias Voltage on the Structure and Properties of Cunitinbcr Dual-Phase High Entropy Alloy Films
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Xiaokang Zeng, Yan Tao Li, Xue Dong Zhang, Mao Liu, Jianzhong Ye, Xiao Lai Qiu, Xin Jiang, and Yong Xiang Leng
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History ,Polymers and Plastics ,Business and International Management ,Industrial and Manufacturing Engineering - Published
- 2022
136. The Morphological Characteristics and Phylogenetic Analyses Revealed an Additional Taxon in Heteroradulum (Auriculariales)
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Jia-Jin Li, Chang-Lin Zhao, and Chao-Mao Liu
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taxonomy ,wood-inhabiting fungi ,Ecology ,QH301-705.5 ,Ecological Modeling ,corticioid fungi ,phylogeny ,Yunnan Province ,Biology (General) ,Agricultural and Biological Sciences (miscellaneous) ,Nature and Landscape Conservation - Abstract
Auriculariales is diverse, embracing a number of corticioid, poroid, and hydnoid genera. The present study covers a new wood-inhabiting fungal species of Heteroradulum niveum sp. nov that is proposed on the basis of a combination of morphological features and molecular evidence. The species is characterized by the resupinate basidiomata, a monomitic hyphal system with generative hyphae with clamp connections; tubular cystidia; two- to four-celled basidia; and allantoid, colorless, thin-walled, smooth, IKI–, CB–, basidiospores (6.5–13.5 × 2.7–5.5 µm). Sequences of ITS and nLSU rRNA gene regions of the specimens were generated, and phylogenetic analyses were carried out with methods of maximum parsimony, maximum likelihood, and Bayesian inference. These phylogenetic analyses inferred from ITS+nLSU indicated that H. niveum is nested in Heteroradulum within Auriculariales. Further study within Heteroradulum on the basis of ITS+nLSU dataset revealed that it formed a monophyletic lineage with a strong support (100% BS, 100% BP, 1.00 BPP) and then grouped with H. yunnanensis.
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- 2022
137. Discussion on Artificial Intelligence Oil Production Technology of Rod Pumped Well
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Yan-hui Zhu, Peng Gao, Liang-liang Qiu, Juan-juan Yan, Yu Han, Peng-gang Chang, and Wen-mao Liu
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- 2022
138. Tandem Sulfonylation/Cyclization of Vinyl Azides with Aryldiazonium Tetrafluoroborates and SO2.
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Chen, Fayun, Quan, Li‐Xia, Zhou, Anxi, Ji, Congbin, Li, Yanhong, Zhu, Xianhong, Mao, Liu‐Liang, and Wan, Jie‐Ping
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PHENANTHRIDINE ,TETRAFLUOROBORATES ,RING formation (Chemistry) ,AZIDES ,SULFUR dioxide - Abstract
An efficient and facile strategy for the synthesis of 6‐(sulfonylmethyl)phenanthridines and its derivatives has been developed via tandem sulfonylation cyclization of vinyl azides under mild conditions in the absence of any catalysts and additives. The reaction simply utilizes easily accessible and cheap K2S2O5 as the sulfur dioxide source, delivering functionalized phenanthridines in moderate to excellent yields with operational simplicity and gram‐scale synthesis, as well as good functional‐group tolerance. [ABSTRACT FROM AUTHOR]
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- 2023
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139. A novel method for monitoring the maxillary tooth movement during orthodontics in 3D space.
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Xin Liu, Mao Liu, Bin Wu, Wencheng Tang, Bin Yan, and Ruxin Lu
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CORRECTIVE orthodontics ,TEETH ,ORTHODONTICS ,MEASUREMENT errors ,CLINICAL medicine - Abstract
Copyright of International Journal of Computerized Dentistry is the property of Quintessence Publishing Company Inc. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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- 2023
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140. Visible-light-mediated tandem phosphorylation/cyclization for the synthesis of phosphorylated oxindoles
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Mao, Liu-Liang, primary, Zhou, An-Xi, additional, Zhu, Xian-Hong, additional, Quan, Li-Xia, additional, Chen, Fayun, additional, Wan, Jie-Ping, additional, and Lai, Yin-Long, additional
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- 2022
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141. Transition-metal-free three-component coupling approach to QUINAP derivatives
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Guo, Xin-Wei, primary, Quan, Li-Xia, additional, Zhu, Xian-Hong, additional, Chen, Fa-Yun, additional, Zhou, An-Xi, additional, Mao, Liu-Liang, additional, Wan, Jie-Ping, additional, and Yang, Shang-Dong, additional
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- 2022
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142. The risk of leukemia in patients with rheumatoid arthritis: a systematic review and meta-analysis
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Zixia Zhao, Jie Chen, Xiao Luo, Mao Liu, Yue He, Lihui Peng, Chengsong He, and Wang-Dong Xu
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030203 arthritis & rheumatology ,education.field_of_study ,medicine.medical_specialty ,Funnel plot ,Leukemia ,business.industry ,Incidence ,Population ,Subgroup analysis ,General Medicine ,Publication bias ,Cochrane Library ,Confidence interval ,Arthritis, Rheumatoid ,03 medical and health sciences ,Study heterogeneity ,0302 clinical medicine ,Rheumatology ,Meta-analysis ,Internal medicine ,medicine ,Humans ,030212 general & internal medicine ,education ,business - Abstract
The relationship between rheumatoid arthritis (RA) and the risk of leukemia was still controversial. This study aimed to assess the risk of leukemia in patients with rheumatoid arthritis by systematic review and meta-analysis.Relevant studies were identified by searching PubMed, Embase, Cochrane Library, and SinoMed up to December 2019. Random effects model analysis was used to pool standardized incidence ratios (SIRs) and 95% confidence interval.A total of 15 relevant studies that met the criteria were included. Compared with the general population, patients with RA showed an increased risk of leukemia (SIR = 1.51, 95% CI: 1.34-1.70). The statistical heterogeneity was moderate with an IOur findings suggested that the risk of leukemia in RA was increased compared with the general population. Key points • This is the first systematic review and meta-analysis to assess the risk of leukemia in RA. • Our study suggested that the risk of leukemia in RA was increased compared with the general population. • This study indicated that the risk of leukemia in RA was higher in non-Asian populations.
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- 2020
143. Clinical and immunological assessment of asymptomatic SARS-CoV-2 infections
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Qin Li, Jiang Gong, Jin Jing Li, Juan Chen, Wei Xu, Bo Wu, Hai Jun Deng, Kun Su, Xiaojun Tang, Xia Mao Liu, Ailong Huang, Yong Zhang, Fa Jin Lv, Fan Zhang, Jie Li Hu, Qiu Lin Shi, Quanxin Long, Jing Fu Qiu, and Jun Yuan
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Adult ,Male ,0301 basic medicine ,China ,medicine.medical_specialty ,Adolescent ,Pneumonia, Viral ,Asymptomatic ,Gastroenterology ,General Biochemistry, Genetics and Molecular Biology ,Serology ,Betacoronavirus ,Young Adult ,03 medical and health sciences ,0302 clinical medicine ,Interquartile range ,Internal medicine ,medicine ,Humans ,Young adult ,Viral shedding ,Child ,Neutralizing antibody ,Asymptomatic Infections ,Pandemics ,Aged ,biology ,SARS-CoV-2 ,business.industry ,COVID-19 ,General Medicine ,Middle Aged ,medicine.disease ,Immunity, Innate ,Hospitalization ,Pneumonia ,030104 developmental biology ,Immunoglobulin G ,030220 oncology & carcinogenesis ,biology.protein ,Cytokines ,Female ,medicine.symptom ,Antibody ,Coronavirus Infections ,business - Abstract
The clinical features and immune responses of asymptomatic individuals infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have not been well described. We studied 37 asymptomatic individuals in the Wanzhou District who were diagnosed with RT-PCR-confirmed SARS-CoV-2 infections but without any relevant clinical symptoms in the preceding 14 d and during hospitalization. Asymptomatic individuals were admitted to the government-designated Wanzhou People's Hospital for centralized isolation in accordance with policy1. The median duration of viral shedding in the asymptomatic group was 19 d (interquartile range (IQR), 15-26 d). The asymptomatic group had a significantly longer duration of viral shedding than the symptomatic group (log-rank P = 0.028). The virus-specific IgG levels in the asymptomatic group (median S/CO, 3.4; IQR, 1.6-10.7) were significantly lower (P = 0.005) relative to the symptomatic group (median S/CO, 20.5; IQR, 5.8-38.2) in the acute phase. Of asymptomatic individuals, 93.3% (28/30) and 81.1% (30/37) had reduction in IgG and neutralizing antibody levels, respectively, during the early convalescent phase, as compared to 96.8% (30/31) and 62.2% (23/37) of symptomatic patients. Forty percent of asymptomatic individuals became seronegative and 12.9% of the symptomatic group became negative for IgG in the early convalescent phase. In addition, asymptomatic individuals exhibited lower levels of 18 pro- and anti-inflammatory cytokines. These data suggest that asymptomatic individuals had a weaker immune response to SARS-CoV-2 infection. The reduction in IgG and neutralizing antibody levels in the early convalescent phase might have implications for immunity strategy and serological surveys.
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- 2020
144. Association of Inpatient Use of Angiotensin-Converting Enzyme Inhibitors and Angiotensin II Receptor Blockers With Mortality Among Patients With Hypertension Hospitalized With COVID-19
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Yufeng Yuan, Liming Liu, Yibin Wang, Jun Lin, Jing Chen, Xiao-Jing Zhang, Shouzhi Fu, Youqin Yan, Jiahong Xia, Fang Lei, Xinghuan Wang, Haitao Wang, Jingjing Cai, Bing Xiao, Xiaodong Huang, Jing Xie, Xiao Zhang, Rohit Loomba, Mingyu Liu, Ping Ye, Juan-Juan Qin, Lihua Zhu, Peter P. Liu, Qingbo Xu, Manhua Chen, Xuewei Huang, Ming-Ming Chen, Yan-Ci Zhao, Pengcheng Luo, Deliang Guo, Weiming Mao, Ye-Mao Liu, Meng Xia, Bing-Hong Zhang, Hongliang Li, Xu Cheng, Yan-Xiao Ji, Peng Zhang, Lijin Lin, Zhi-Gang She, Hongbin Cai, Rhian M. Touyz, Renfu Tan, and Yuanyuan Peng
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Male ,Epidemiology ,Physiology ,coronavirus ,Angiotensin-Converting Enzyme Inhibitors ,Angiotensin II Receptor Blockers ,Cardiorespiratory Medicine and Haematology ,030204 cardiovascular system & hematology ,Pharmacology ,Cardiovascular ,medicine.disease_cause ,inpatients ,0302 clinical medicine ,Viral ,Hospital Mortality ,030212 general & internal medicine ,Original Research ,Coronavirus ,Angiotensin Receptor Antagonists ,biology ,Middle Aged ,angiotensin II receptor blocker ,angiotensin-converting enzyme inhibitor ,ComputingMethodologies_DOCUMENTANDTEXTPROCESSING ,Female ,Coronavirus Infections ,Cardiology and Cardiovascular Medicine ,2019-20 coronavirus outbreak ,hypertension ,Coronavirus disease 2019 (COVID-19) ,Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) ,Pneumonia, Viral ,Clinical Sciences ,03 medical and health sciences ,Clinical Research ,medicine ,Humans ,cardiovascular diseases ,Pandemics ,Aged ,Inpatients ,SARS-CoV-2 ,business.industry ,COVID-19 ,Angiotensin-converting enzyme ,Pneumonia ,Good Health and Well Being ,Cardiovascular System & Hematology ,biology.protein ,business - Abstract
Supplemental Digital Content is available in the text., Rationale: Use of ACEIs (angiotensin-converting enzyme inhibitors) and ARBs (angiotensin II receptor blockers) is a major concern for clinicians treating coronavirus disease 2019 (COVID-19) in patients with hypertension. Objective: To determine the association between in-hospital use of ACEI/ARB and all-cause mortality in patients with hypertension and hospitalized due to COVID-19. Methods and Results: This retrospective, multi-center study included 1128 adult patients with hypertension diagnosed with COVID-19, including 188 taking ACEI/ARB (ACEI/ARB group; median age 64 [interquartile range, 55–68] years; 53.2% men) and 940 without using ACEI/ARB (non-ACEI/ARB group; median age 64 [interquartile range 57–69]; 53.5% men), who were admitted to 9 hospitals in Hubei Province, China from December 31, 2019 to February 20, 2020. In mixed-effect Cox model treating site as a random effect, after adjusting for age, gender, comorbidities, and in-hospital medications, the detected risk for all-cause mortality was lower in the ACEI/ARB group versus the non-ACEI/ARB group (adjusted hazard ratio, 0.42 [95% CI, 0.19–0.92]; P=0.03). In a propensity score-matched analysis followed by adjusting imbalanced variables in mixed-effect Cox model, the results consistently demonstrated lower risk of COVID-19 mortality in patients who received ACEI/ARB versus those who did not receive ACEI/ARB (adjusted hazard ratio, 0.37 [95% CI, 0.15–0.89]; P=0.03). Further subgroup propensity score-matched analysis indicated that, compared with use of other antihypertensive drugs, ACEI/ARB was also associated with decreased mortality (adjusted hazard ratio, 0.30 [95% CI, 0.12–0.70]; P=0.01) in patients with COVID-19 and coexisting hypertension. Conclusions: Among hospitalized patients with COVID-19 and coexisting hypertension, inpatient use of ACEI/ARB was associated with lower risk of all-cause mortality compared with ACEI/ARB nonusers. While study interpretation needs to consider the potential for residual confounders, it is unlikely that in-hospital use of ACEI/ARB was associated with an increased mortality risk.
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- 2020
145. Antibody responses to SARS-CoV-2 in patients with COVID-19
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Hua Wen Liu, Jun Yuan, Jin Jing Li, Hai Jun Deng, Shao Bo Wu, Xiao Ping Cui, Man Man Zhu, Fang Gong, Juan Chen, Jie Li Hu, Xiao He Luo, Zhi Jie Li, Xiao Feng Li, Wen Guang Tian, Li Hu, Liu Ping, Chun Hui Lang, Jing Wang, Kun Deng, Yuan Hu, Kun Wang, Li Hua Yu, Jing Fu Qiu, Deqiang Wang, Cheng Jun Xue, Yong Zhang, Bai Zhong Liu, Xiao-li Zhang, Yin Yin Xu, Yong Lin, Qing Jun Yang, Fan Zhang, Xian Xiang Zhang, Zhan Mo, Xue Fei Cai, Yao Kai Chen, Qin Li, Ailong Huang, Ji Hua Ren, Xia Mao Liu, De Chun Zhang, Ni Tang, Quanxin Long, Gui Cheng Wu, Jiang Lin Xiang, Li Wang, Pu Liao, Xiaojun Tang, Hong Xin Du, Zheng Zhou, and Chang Chun Niu
- Subjects
Adult ,Male ,0301 basic medicine ,Coronavirus disease 2019 (COVID-19) ,Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) ,Pneumonia, Viral ,Antibodies, Viral ,Antiviral Agents ,Asymptomatic ,General Biochemistry, Genetics and Molecular Biology ,Serology ,Betacoronavirus ,03 medical and health sciences ,0302 clinical medicine ,Humans ,Medicine ,Seroconversion ,Pandemics ,Aged ,biology ,SARS-CoV-2 ,business.industry ,COVID-19 ,General Medicine ,Middle Aged ,medicine.disease ,Pneumonia ,Titer ,030104 developmental biology ,Immunoglobulin M ,Immunoglobulin G ,030220 oncology & carcinogenesis ,Antibody Formation ,Immunology ,biology.protein ,Female ,Antibody ,medicine.symptom ,Coronavirus Infections ,business - Abstract
We report acute antibody responses to SARS-CoV-2 in 285 patients with COVID-19. Within 19 days after symptom onset, 100% of patients tested positive for antiviral immunoglobulin-G (IgG). Seroconversion for IgG and IgM occurred simultaneously or sequentially. Both IgG and IgM titers plateaued within 6 days after seroconversion. Serological testing may be helpful for the diagnosis of suspected patients with negative RT-PCR results and for the identification of asymptomatic infections.
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- 2020
146. Paeoniflorin Attenuates Myocardial Fibrosis in Isoprenaline-induced Chronic Heart Failure Rats via Inhibiting P38 MAPK Pathway
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Jie Feng, Mao Liu, Qian Du, Jiao Ai, and Zhan Lv
- Subjects
Male ,Cardiac function curve ,medicine.medical_specialty ,animal structures ,MAP Kinase Signaling System ,p38 mitogen-activated protein kinases ,medicine.medical_treatment ,Down-Regulation ,Biochemistry ,Transforming Growth Factor beta1 ,chemistry.chemical_compound ,Glucosides ,Internal medicine ,Isoprenaline ,Genetics ,medicine ,Animals ,business.industry ,Isoproterenol ,Immunosuppression ,medicine.disease ,Paeoniflorin ,Fibrosis ,Rats ,Disease Models, Animal ,Endocrinology ,Gene Expression Regulation ,chemistry ,Heart failure ,Heart Function Tests ,Monoterpenes ,Myocardial fibrosis ,Cardiomyopathies ,business ,medicine.drug ,Transforming growth factor - Abstract
Paeoniforin (Pae) is a monoterpenoid glycoside compound and has many biological activities, such as immunosuppression, anti-inflammation and anti-cell proliferation. However, the effects and mechanisms of Pae on chronic heart failure (CHF) remain unclear. This study was conducted to assess the effects and mechanisms of Pae on myocardial fbrosis in isoprenaline (Iso)-induced CHF rats. Pae (20 mg/kg) was intragastrically administrated to CHF rats for 6 weeks. Cardiac structure and function were assessed. The protein and mRNA levels of transforming growth factor β1 (TGF-β1) and p38 were detected. Compared to Iso group, Pae could alleviate myocardial fibrosis and improve cardiac function in CHF rats. The levels of collagen volume fraction (13.75%±3.77% vs. 30.97%±4.22%, P
- Published
- 2020
147. Steady-state periodic solutions of the nonlinear wave propagation problem of a one-dimensional lattice using a new methodology with an incremental harmonic balance method that handles time delays
- Author
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Xuefeng Wang, Weidong Zhu, and Mao Liu
- Subjects
Computer program ,Wave propagation ,Applied Mathematics ,Mechanical Engineering ,Aerospace Engineering ,Ocean Engineering ,Delay differential equation ,Nonlinear system ,symbols.namesake ,Harmonic balance ,Control and Systems Engineering ,Lattice (order) ,Jacobian matrix and determinant ,symbols ,Applied mathematics ,Electrical and Electronic Engineering ,Newton's method ,Mathematics - Abstract
A new methodology is developed in this work to solve a one-dimensional (1D) nonlinear wave propagation problem. In its response, the space variable is converted to time functions at different locations, and the resultant time functions are merged with the time variable. Since the merged variables are essentially time-delay variables, the main point of the methodology is that the governing equation of the nonlinear wave propagation problem can be converted to a corresponding nonlinear delay differential equation (DDE) with multiple delays. The new methodology is shown how to formulate the converted DDE, and a modified incremental harmonic balance method is used to solve the 1D nonlinear DDE by introducing a delay matrix operator, where a formula of the Jacobian matrix is derived and can be efficiently and automatically used in the Newton method. This new methodology is demonstrated by solving examples of 1D monatomic chains under the nonlinear Hertzian contact law and with cubic springs. Results well match those in previous works, but derivation effort of solutions and calculation time can be significantly reduced here. When the algorithm of the methodology is compiled as a computer program, there is no additional derivation required to solve wave propagation problems associated with different governing equations.
- Published
- 2020
148. Voltammetric Detection of Catechol and Dopamine Based on a Supramolecular Composite Prepared from Multifarene[3,3] and Reduced Graphene Oxide
- Author
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Mao Liu, Lin Sun, Yong-Yi Zhao, Xian-Yi Jin, Huan Luo, Zhu Tao, Jian-Mei Yang, Hang Cong, and Qing-Mei Ge
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Catechol ,Materials science ,Graphene ,Composite number ,Supramolecular chemistry ,Oxide ,Combinatorial chemistry ,Analytical Chemistry ,law.invention ,chemistry.chemical_compound ,chemistry ,Dopamine ,law ,Electrochemistry ,medicine ,medicine.drug - Published
- 2020
149. Emotional and Autonomic Processing of Olfactory Stimuli Is Compromised in Patients with a History of Mild Traumatic Brain Injury
- Author
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Max J. Hilz, Ruihao Wang, Thomas Hummel, Klemens Winder, Steven R. Flanagan, Mao Liu, Dafin F. Muresanu, and Katharina M. Hösl
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Adult ,Male ,Traumatic brain injury ,business.industry ,Emotions ,Blood Pressure ,Recognition, Psychology ,Emotional processing ,Autonomic Nervous System ,Olfactory Perception ,medicine.disease ,Smell ,Heart Rate ,Olfactory stimulation ,medicine ,Humans ,Female ,In patient ,Neurology (clinical) ,business ,Neuroscience ,Brain Concussion - Abstract
Patients with a history of mild traumatic brain injury (post-mTBI patients) may have enduring cardiovascular-autonomic dysregulation and emotional problems. Olfactory stimulation (OS) triggers emotional and cardiovascular-autonomic responses that might be compromised in post-mTBI patients. We therefore evaluated these responses to OS in post-mTBI patients. In 17 post-mTBI patients (interval since mTBI: 32.4 ± 6.8 months) and 17 age- and sex-matched controls, we recorded respiration, electrocardiographic RR intervals, and systolic and diastolic blood pressures (BPsys, BPdia) before and during pleasant vanilla stimulation and unpleasant hydrogen sulphide (H2S) stimulation. Participants rated OS-related pleasantness, arousal, intensity, and familiarity on 9-point Likert scales. Analyses of variance (ANOVAs) with post hoc analyses compared parameters within each group before and during OS. To assess associations between pleasantness, arousal, intensity, and familiarity, we correlated OS scores within groups (significance
- Published
- 2020
150. A high-sensitive sensor with HEPES-enhanced electrochemiluminescence of benzo[3]uril for Fe3+ and its application in human serum
- Author
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Xian-Yi Jin, Yao Lei, Mao Liu, Jian-Mei Yang, Zhu Tao, Hang Cong, Fei Qiu, and Qing-Mei Ge
- Subjects
Sensor system ,Detection limit ,HEPES ,Aqueous solution ,02 engineering and technology ,010402 general chemistry ,021001 nanoscience & nanotechnology ,Serum samples ,01 natural sciences ,Biochemistry ,0104 chemical sciences ,Analytical Chemistry ,chemistry.chemical_compound ,chemistry ,Electrochemistry ,Environmental Chemistry ,Electrochemiluminescence ,0210 nano-technology ,Luminescence ,Selectivity ,Spectroscopy ,Nuclear chemistry - Abstract
An electrochemiluminescence (ECL) sensor based on a benzo[3]uril-modified glassy carbon electrode with sensitized luminescence, with the coexistence of 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid (HEPES) as the coreactant, was successfully constructed. The sensitization mechanism was proposed by analyzing the results of the control experiments for establishing the relationship of the luminescence effect with the concentration of HEPES. Under the optimized conditions, the fabricated sensor system was applied for the detection of Fe3+ in an aqueous solution with good sensitivity and selectivity. A low detection limit of 0.41 nM was achieved, indicating superior sensor performance over the previous analytical methods. The ECL sensor system was employed for the detection of Fe3+ in human serum samples to produce excellent recoveries ranging from 96.17% to 101.81%.
- Published
- 2020
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