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101. Von Willebrand Factor Deficiency

Author

Balemans, Wendy, primary, Van Hul, Wim, additional, Valko, Marian, additional, Moncol, Jan, additional, Denson, Lee A., additional, Mela, Maria, additional, Thalheimer, Ulrich, additional, Samonakis, Dimitrios, additional, Burroughs, Andrew K., additional, Leung, Alexander K. C., additional, Sauve, Reginald S., additional, Robson, William Lane M., additional, Bornstein, Stefan R., additional, Aunapuu, Marina, additional, Arend, Andres, additional, Recher, Mike, additional, Lang, Karl S., additional, Melms, Arthur, additional, Sunderkötter, Cord, additional, Sindrilaru, Anca, additional, Divizia, Maria Teresa, additional, Lerone, Margherita, additional, Ravazzolo, Roberto, additional, Aggarwal, Vimla S., additional, Arnold, Jelena S., additional, Blonska*, Anna, additional, Morrow, Bernice E., additional, Kubitz, Ralf, additional, Yamaki, Takashi, additional, Connelly, Kim A., additional, Gilbert, Richard E., additional, Ma, Lucia K., additional, Ma, Patrick T. S., additional, Moorjani, Narain, additional, Sugden, Peter H., additional, Depre, Christophe, additional, Selvanayagam, Joseph B., additional, Burow, Annika, additional, Delacrétaz, Etienne, additional, Chen, Zhuang, additional, Shou, Weinian, additional, Stockfleth, Eggert, additional, Nindl, Ingo, additional, Brandt, Thomas, additional, Strupp, Michael, additional, Theil, Diethilde, additional, Andresen, Brage Storstein, additional, Ludwig, Amei, additional, Hengel, Hartmut, additional, Bode, Johannes G., additional, Erhardt, Andreas, additional, Oppido, Guido, additional, Napoleone, Carlo Pace, additional, Gargiulo, Gaetano, additional, Biesalski, Hans K., additional, Gdynia, Hans-Jürgen, additional, Ludolph, Albert C., additional, Bitsch, Roland, additional, Akhilender, Naidu K., additional, Zittermann, Armin, additional, Azzi, Angelo, additional, Negis, Yesim, additional, Markel, Arie, additional, Kfir, Nir, additional, Bayer, Johannes, additional, Beissert, Stefan, additional, Chou, Janice Y., additional, Mansfield, Brian C., additional, Hartmann, Arndt, additional, Dietmaier, Wolfgang, additional, and Ten Cate, Hugo, additional

Published
2009
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102. Vitamin D Excess

Author

Balemans, Wendy, primary, Van Hul, Wim, additional, Valko, Marian, additional, Moncol, Jan, additional, Denson, Lee A., additional, Mela, Maria, additional, Thalheimer, Ulrich, additional, Samonakis, Dimitrios, additional, Burroughs, Andrew K., additional, Leung, Alexander K. C., additional, Sauve, Reginald S., additional, Robson, William Lane M., additional, Bornstein, Stefan R., additional, Aunapuu, Marina, additional, Arend, Andres, additional, Recher, Mike, additional, Lang, Karl S., additional, Melms, Arthur, additional, Sunderkötter, Cord, additional, Sindrilaru, Anca, additional, Divizia, Maria Teresa, additional, Lerone, Margherita, additional, Ravazzolo, Roberto, additional, Aggarwal, Vimla S., additional, Arnold, Jelena S., additional, Blonska*, Anna, additional, Morrow, Bernice E., additional, Kubitz, Ralf, additional, Yamaki, Takashi, additional, Connelly, Kim A., additional, Gilbert, Richard E., additional, Ma, Lucia K., additional, Ma, Patrick T. S., additional, Moorjani, Narain, additional, Sugden, Peter H., additional, Depre, Christophe, additional, Selvanayagam, Joseph B., additional, Burow, Annika, additional, Delacrétaz, Etienne, additional, Chen, Zhuang, additional, Shou, Weinian, additional, Stockfleth, Eggert, additional, Nindl, Ingo, additional, Brandt, Thomas, additional, Strupp, Michael, additional, Theil, Diethilde, additional, Andresen, Brage Storstein, additional, Ludwig, Amei, additional, Hengel, Hartmut, additional, Bode, Johannes G., additional, Erhardt, Andreas, additional, Oppido, Guido, additional, Napoleone, Carlo Pace, additional, Gargiulo, Gaetano, additional, Biesalski, Hans K., additional, Gdynia, Hans-Jürgen, additional, Ludolph, Albert C., additional, Bitsch, Roland, additional, Akhilender, Naidu K., additional, Zittermann, Armin, additional, Azzi, Angelo, additional, Negis, Yesim, additional, Markel, Arie, additional, Kfir, Nir, additional, Bayer, Johannes, additional, Beissert, Stefan, additional, Chou, Janice Y., additional, Mansfield, Brian C., additional, Hartmann, Arndt, additional, Dietmaier, Wolfgang, additional, and Ten Cate, Hugo, additional

Published
2009
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103. Viral Hepatitis, Acute

Author

Balemans, Wendy, primary, Van Hul, Wim, additional, Valko, Marian, additional, Moncol, Jan, additional, Denson, Lee A., additional, Mela, Maria, additional, Thalheimer, Ulrich, additional, Samonakis, Dimitrios, additional, Burroughs, Andrew K., additional, Leung, Alexander K. C., additional, Sauve, Reginald S., additional, Robson, William Lane M., additional, Bornstein, Stefan R., additional, Aunapuu, Marina, additional, Arend, Andres, additional, Recher, Mike, additional, Lang, Karl S., additional, Melms, Arthur, additional, Sunderkötter, Cord, additional, Sindrilaru, Anca, additional, Divizia, Maria Teresa, additional, Lerone, Margherita, additional, Ravazzolo, Roberto, additional, Aggarwal, Vimla S., additional, Arnold, Jelena S., additional, Blonska*, Anna, additional, Morrow, Bernice E., additional, Kubitz, Ralf, additional, Yamaki, Takashi, additional, Connelly, Kim A., additional, Gilbert, Richard E., additional, Ma, Lucia K., additional, Ma, Patrick T. S., additional, Moorjani, Narain, additional, Sugden, Peter H., additional, Depre, Christophe, additional, Selvanayagam, Joseph B., additional, Burow, Annika, additional, Delacrétaz, Etienne, additional, Chen, Zhuang, additional, Shou, Weinian, additional, Stockfleth, Eggert, additional, Nindl, Ingo, additional, Brandt, Thomas, additional, Strupp, Michael, additional, Theil, Diethilde, additional, Andresen, Brage Storstein, additional, Ludwig, Amei, additional, Hengel, Hartmut, additional, Bode, Johannes G., additional, Erhardt, Andreas, additional, Oppido, Guido, additional, Napoleone, Carlo Pace, additional, Gargiulo, Gaetano, additional, Biesalski, Hans K., additional, Gdynia, Hans-Jürgen, additional, Ludolph, Albert C., additional, Bitsch, Roland, additional, Akhilender, Naidu K., additional, Zittermann, Armin, additional, Azzi, Angelo, additional, Negis, Yesim, additional, Markel, Arie, additional, Kfir, Nir, additional, Bayer, Johannes, additional, Beissert, Stefan, additional, Chou, Janice Y., additional, Mansfield, Brian C., additional, Hartmann, Arndt, additional, Dietmaier, Wolfgang, additional, and Ten Cate, Hugo, additional

Published
2009
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111. The gene for glycogen-storage disease type 1b maps to chromosome 11q23

Author

Annabi, Borhane, Hiraiwa, Hisayuki, Mansfield, Brian C., Lei, Ke-Jian, Ubagai, Tsuneyuki, Polymeropoulos, Mihael H., Moses, Shimon W., Parvari, Ruti, Hershkovitz, Eli, Mandel, Hanna, Fryman, Moshe, and Chou, Janice Yang

Subjects
Glycogenosis -- Genetic aspects, Consanguinity -- Health aspects, Biological sciences
Abstract

A locus marked by genetic markers that span a 3-cM region on chromosome 11q23 have been linked to glycogen-storage disease type 1 (GSD-1). GSD-1, also known as von Gierke disease, is caused by a deficiency in microsomal glucose-6-phosphatase (G6Pase) activity. Only GSD-1b patients, of patients with the four types of the autosomal recessive disorder, suffer infectious complications, the result of the heritable neutropenia and deficiencies in functions of neutrophils and monocytes. The GSD-1b patients have complications not easily blamed on deficiency of G6Pase. In all the subgroups other clinical signs and symptoms are the same and caused by abnormalities in metabolism of glucose-6-phosphate (G6P). More research will give insight into genetic links of G6P metabolism and neutrophil-monocyte dysfunction. Consanguineous families and one nonconsanguineous family of Bedouin, North African, Iranian Jewish, Israeli Arab, Pakistani and European origins were studied.

Published
1998

116. SP-100 reactor with Brayton conversion for lunar surface applications

Author

Mason, Lee S, Rodriguez, Carlos D, Mckissock, Barbara I, Hanlon, James C, and Mansfield, Brian C

Subjects
Spacecraft Propulsion And Power
Abstract

Examined here is the potential for integrating Brayton-cycle power conversion with the SP-100 reactor for lunar surface power system applications. Two designs were characterized and modeled. The first design integrates a 100-kWe SP-100 Brayton power system with a lunar lander. This system is intended to meet early lunar mission power needs while minimizing on-site installation requirements. Man-rated radiation protection is provided by an integral multilayer, cylindrical lithium hydride/tungsten (LiH/W) shield encircling the reactor vessel. Design emphasis is on ease of deployment, safety, and reliability, while utilizing relatively near-term technology. The second design combines Brayton conversion with the SP-100 reactor in a erectable 550-kWe powerplant concept intended to satisfy later-phase lunar base power requirements. This system capitalizes on experience gained from operating the initial 100-kWe module and incorporates some technology improvements. For this system, the reactor is emplaced in a lunar regolith excavation to provide man-rated shielding, and the Brayton engines and radiators are mounted on the lunar surface and extend radially from the central reactor. Design emphasis is on performance, safety, long life, and operational flexibility.

Published
1992

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