273 results on '"Malaspina M"'
Search Results
102. The Planck Low Frequency Instrument
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Mandolesi, N., Burigana, C., Butler, R. C., Cuttaia, F., Rosa, A., Finelli, F., Franceschi, E., Gruppuso, A., Malaspina, M., Gianluca Morgante, Morigi, G., Popa, L., Sandri, M., Stringhetti, L., Terenzi, L., Valenziano, L., and Villa, F.
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Astrophysics (astro-ph) ,Astrophysics::Instrumentation and Methods for Astrophysics ,FOS: Physical sciences ,Astrophysics::Cosmology and Extragalactic Astrophysics ,Astrophysics - Abstract
Planck is the third generation of mm-wave instruments designed for space observations of the cosmic microwave background (CMB) anisotropies within the new Cosmic Vision 2020 ESA Science Program. Planck will map the whole sky with unprecedented sensitivity, angular resolution, and frequency coverage, and it likely leads us to the final comprehension of the CMB anisotropies. The Low Frequency Instrument (LFI), operating in the 30-70 GHz range, is one of the two instruments onboard Planck satellite, sharing the focal region of a 1.5 meter off-axis dual reflector telescope together with the High Frequency Instrument (HFI) operating at 100-857 GHz. We present LFI and discuss the major instrumental systematic effects that could degrade the measurements and the solutions adopted in the design and data analysis phase in order to adequately reduce and control them., 5 pages, 1 figure, On behalf of LFI Consortium,to be published in proc. JENAM 2004 meeting "The many scales in the Universe", Granada, Spain, 13-17 Sept. 2004
103. PCN4 Cervical Human Papilloma Virus (HPV) DNA Primary Screening Test Results of the Experience of a Regional Laboratory in Central Italy
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Passamonti, B.U., Bulletti, S., Gustinucci, D., Martinelli, N., D'Amico, M.R., Spita, N., Malaspina, M., Carlani, A., DI Dato, E., Galeazzi, P., Tintori, B., D'angelo, V., and Calvi, C.
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104. Planck early results. III. First assessment of the Low Frequency Instrument in-flight performance ⋆
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Mennella, A., Bersanelli, M., Butler, R. C., Curto, A., Cuttaia, F., Davis, R. J., Dick, J., Frailis, M., Galeotta, S., Gregorio, A., Kurki-Suonio, H., Lawrence, C. R., Leach, S., Leahy, J. P., Lowe, S., Maino, D., Mandolesi, N., Maris, M., Martínez-González, E., Meinhold, P. R., Morgante, G., Pearson, D., Perrotta, F., Polenta, G., Poutanen, T., Sandri, M., Seiffert, M. D., Suur-Uski, A.-S., Tavagnacco, D., Terenzi, L., Tomasi, M., Valiviita, J., Villa, F., Watson, R., Wilkinson, A., Zacchei, A., Zonca, A., Aja, B., Artal, E., Baccigalupi, C., Banday, A. J., Barreiro, R. B., Bartlett, J. G., Bartolo, N., Battaglia, P., Bennett, K., Bonaldi, A., Bonavera, L., Borrill, J., Bouchet, F. R., Burigana, C., Cabella, P., Cappellini, B., Chen, X., Colombo, L., Cruz, M., Danese, L., D’Arcangelo, O., Davies, R. D., de Gasperis, G., de Rosa, A., de Zotti, G., Dickinson, C., Diego, J. M., Donzelli, S., Efstathiou, G., Enßlin, T. A., Eriksen, H. K., Falvella, M. C., Finelli, F., Foley, S., Franceschet, C., Franceschi, E., Gaier, T. C., Génova-Santos, R. T., George, D., Gómez, F., González-Nuevo, J., Górski, K. M., Gruppuso, A., Hansen, F. K., Herranz, D., Herreros, J. M., Hoyland, R. J., Hughes, N., Jewell, J., Jukkala, P., Juvela, M., Kangaslahti, P., Keihänen, E., Keskitalo, R., Kilpia, V.-H., Kisner, T. S., Knoche, J., Knox, L., Laaninen, M., Lähteenmäki, A., Lamarre, J.-M., Leonardi, R., León-Tavares, J., Leutenegger, P., Lilje, P. B., López-Caniego, M., Lubin, P. M., Malaspina, M., Marinucci, D., Massardi, M., Matarrese, S., Matthai, F., Melchiorri, A., Mendes, L., Miccolis, M., Migliaccio, M., Mitra, S., Moss, A., Natoli, P., Nesti, R., Nørgaard-Nielsen, H. U., Pagano, L., Paladini, R., Paoletti, D., Partridge, B., Pasian, F., Pettorino, V., Pietrobon, D., Pospieszalski, M., Prézeau, G., Prina, M., Procopio, P., Puget, J.-L., Quercellini, C., Rachen, J. P., Rebolo, R., Reinecke, M., Ricciardi, S., Robbers, G., Rocha, G., Roddis, N., Rubi no-Martín, J. A., Savelainen, M., Scott, D., Silvestri, R., Simonetto, A., Sjoman, P., Smoot, G. F., Sozzi, C., Stringhetti, L., Tauber, J. A., Tofani, G., Toffolatti, L., Tuovinen, J., Türler, M., Umana, G., Valenziano, L., Varis, J., Vielva, P., Vittorio, N., Wade, L. A., Watson, C., White, S. D. M., and Winder, F.
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The scientific performance of the Planck Low Frequency Instrument (LFI) after one year of in-orbit operation is presented. We describe the main optical parameters and discuss photometric calibration, white noise sensitivity, and noise properties. A preliminary evaluation of the impact of the main systematic effects is presented. For each of the performance parameters, we outline the methods used to obtain them from the flight data and provide a comparison with pre-launch ground assessments, which are essentially confirmed in flight.
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- 2011
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105. Planckpre-launch status: The Planck-LFI programme
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Mandolesi, N., Bersanelli, M., Butler, R. C., Artal, E., Baccigalupi, C., Balbi, A., Banday, A. J., Barreiro, R. B., Bartelmann, M., Bennett, K., Bhandari, P., Bonaldi, A., Borrill, J., Bremer, M., Burigana, C., Bowman, R. C., Cabella, P., Cantalupo, C., Cappellini, B., Courvoisier, T., Crone, G., Cuttaia, F., Danese, L., D'Arcangelo, O., Davies, R. D., Davis, R. J., De Angelis, L., de Gasperis, G., De Rosa, A., De Troia, G., de Zotti, G., Dick, J., Dickinson, C., Diego, J. M., Donzelli, S., Dörl, U., Dupac, X., Enßlin, T. A., Eriksen, H. K., Falvella, M. C., Finelli, F., Frailis, M., Franceschi, E., Gaier, T., Galeotta, S., Gasparo, F., Giardino, G., Gomez, F., Gonzalez-Nuevo, J., Górski, K. M., Gregorio, A., Gruppuso, A., Hansen, F., Hell, R., Herranz, D., Herreros, J. M., Hildebrandt, S., Hovest, W., Hoyland, R., Huffenberger, K., Janssen, M., Jaffe, T., Keihänen, E., Keskitalo, R., Kisner, T., Kurki-Suonio, H., Lähteenmäki, A., Lawrence, C. R., Leach, S. M., Leahy, J. P., Leonardi, R., Levin, S., Lilje, P. B., López-Caniego, M., Lowe, S. R., Lubin, P. M., Maino, D., Malaspina, M., Maris, M., Marti-Canales, J., Martinez-Gonzalez, E., Massardi, M., Matarrese, S., Matthai, F., Meinhold, P., Melchiorri, A., Mendes, L., Mennella, A., Morgante, G., Morigi, G., Morisset, N., Moss, A., Nash, A., Natoli, P., Nesti, R., Paine, C., Partridge, B., Pasian, F., Passvogel, T., Pearson, D., Pérez-Cuevas, L., Perrotta, F., Polenta, G., Popa, L. A., Poutanen, T., Prezeau, G., Prina, M., Rachen, J. P., Rebolo, R., Reinecke, M., Ricciardi, S., Riller, T., Rocha, G., Roddis, N., Rohlfs, R., Rubiño-Martin, J. A., Salerno, E., Sandri, M., Scott, D., Seiffert, M., Silk, J., Simonetto, A., Smoot, G. F., Sozzi, C., Sternberg, J., Stivoli, F., Stringhetti, L., Tauber, J., Terenzi, L., Tomasi, M., Tuovinen, J., Türler, M., Valenziano, L., Varis, J., Vielva, P., Villa, F., Vittorio, N., Wade, L., White, M., White, S., Wilkinson, A., Zacchei, A., and Zonca, A.
- Abstract
This paper provides an overview of the Low Frequency Instrument (LFI) programme within the ESA Planck mission. The LFI instrument has been developed to produce high precision maps of the microwave sky at frequencies in the range 27–77 GHz, below the peak of the cosmic microwave background (CMB) radiation spectrum. The scientific goals are described, ranging from fundamental cosmology to Galactic and extragalactic astrophysics. The instrument design and development are outlined, together with the model philosophy and testing strategy. The instrument is presented in the context of the Planck mission. The LFI approach to ground and inflight calibration is described. We also describe the LFI ground segment. We present the results of a number of tests demonstrating the capability of the LFI data processing centre (DPC) to properly reduce and analyse LFI flight data, from telemetry information to calibrated and cleaned time ordered data, sky maps at each frequency (in temperature and polarization), component emission maps (CMB and diffuse foregrounds), catalogs for various classes of sources (the Early Release Compact Source Catalogue and the Final Compact Source Catalogue). The organization of the LFI consortium is briefly presented as well as the role of the core team in data analysis and scientific exploitation. All tests carried out on the LFI flight model demonstrate the excellent performance of the instrument and its various subunits. The data analysis pipeline has been tested and its main steps verified. In the first three months after launch, the commissioning, calibration, performance, and verification phases will be completed, after which Planck will begin its operational life, in which LFI will have an integral part.
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- 2010
106. The Focal Attention Window Size Explains Letter Substitution Errors in Reading
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Marialuisa Martelli, Lisa S. Arduino, Laura Veronelli, Silvia Primativo, Massimo Corbo, Roberta Daini, Manuela Malaspina, Andrea Albonico, Daini, R, Primativo, S, Albonico, A, Veronelli, L, Malaspina, M, Corbo, M, Martelli, M, and Arduino, L
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media_common.quotation_subject ,M-PSI/02 - PSICOBIOLOGIA E PSICOLOGIA FISIOLOGICA ,Article ,Single word reading ,Task (project management) ,Neglect ,lcsh:RC321-571 ,Crowding phenomenon ,crowding phenomenon ,focal attention ,neglect dyslexia ,single word reading ,substitution errors ,Reading (process) ,Substitution error ,Neglect dyslexia ,medicine ,Association (psychology) ,lcsh:Neurosciences. Biological psychiatry. Neuropsychiatry ,media_common ,General Neuroscience ,Dyslexia ,medicine.disease ,Crowding ,Focus (linguistics) ,Psychology ,Cognitive psychology ,Type I and type II errors ,Focal attention - Abstract
Acquired Neglect Dyslexia is often associated with right-hemisphere brain damage and is mainly characterized by omissions and substitutions in reading single words. Martelli et al. proposed in 2011 that these two types of error are due to different mechanisms. Omissions should depend on neglect plus an oculomotor deficit, whilst substitutions on the difficulty with which the letters are perceptually segregated from each other (i.e., crowding phenomenon). In this study, we hypothesized that a deficit of focal attention could determine a pathological crowding effect, leading to imprecise letter identification and consequently substitution errors. In Experiment 1, three brain-damaged patients, suffering from peripheral dyslexia, mainly characterized by substitutions, underwent an assessment of error distribution in reading pseudowords and a T detection task as a function of cue size and timing, in order to measure focal attention. Each patient, when compared to a control group, showed a deficit in adjusting the attentional focus. In Experiment 2, a group of 17 right-brain-damaged patients were asked to perform the focal attention task and to read single words and pseudowords as a function of inter-letter spacing. The results allowed us to confirm a more general association between substitution-type reading errors and the performance in the focal attention task.
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- 2021
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107. Self-face and self-body advantages in congenital prosopagnosia: evidence for a common mechanism
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Manuela Malaspina, Roberta Daini, Andrea Albonico, Malaspina, M, Albonico, A, and Daini, R
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Adult ,Male ,medicine.medical_specialty ,Self recognition ,Audiology ,M-PSI/02 - PSICOBIOLOGIA E PSICOLOGIA FISIOLOGICA ,behavioral disciplines and activities ,050105 experimental psychology ,Young Adult ,03 medical and health sciences ,0302 clinical medicine ,medicine ,Humans ,0501 psychology and cognitive sciences ,prosopagnosia, face recognition, body recognition,self-recognition ,Foot ,Mechanism (biology) ,General Neuroscience ,Self ,05 social sciences ,Recognition, Psychology ,Hand ,Self Concept ,body regions ,Prosopagnosia ,Pattern Recognition, Visual ,Face ,Face (geometry) ,Female ,Psychology ,Facial Recognition ,030217 neurology & neurosurgery - Abstract
Prosopagnosia is a disorder leading to difficulties in recognizing faces. However, recent evidence suggests that individuals with congenital prosopagnosia can achieve considerable accuracy when they have to recognize their own faces (self-face advantage). Yet, whether this advantage is face-specific or not is still unclear. Here, we aimed to investigate whether individuals with congenital prosopagnosia show a self-advantage also in recognizing other self body-parts and, if so, whether the advantage for the body parts differs from the one characterizing the self-face. Eight individuals with congenital prosopagnosia and 22 controls underwent a delayed matching task in which they were required to recognize faces, hands, and feet belonging to the self or to others. Controls showed a similar self-advantage for all the stimuli tested; by contrast, individuals with congenital prosopagnosia showed a larger self-advantage with faces compared to hands and feet, mainly driven by their deficit with others’ faces. In both groups the self-advantages for the different body parts were strongly and significantly correlated. Our data suggest that the self-face advantage showed by individuals with congenital prosopagnosia is not face-specific and that the same mechanism could be responsible for both the self-face and self body-part advantages.
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- 2018
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108. Mapping self-face recognition strategies in congenital prosopagnosia
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Roberto Caldara, Andrea Albonico, Junpeng Lao, Roberta Daini, Manuela Malaspina, Malaspina, M, Albonico, A, Lao, J, Caldara, R, and Daini, R
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Adult ,Male ,Eye movement ,Matching (statistics) ,Eye Movements ,media_common.quotation_subject ,Fixation, Ocular ,Facial recognition system ,050105 experimental psychology ,Task (project management) ,Young Adult ,03 medical and health sciences ,Discrimination, Psychological ,0302 clinical medicine ,Face perception ,Perception ,Reaction Time ,Humans ,0501 psychology and cognitive sciences ,media_common ,05 social sciences ,Recognition, Psychology ,Congenital prosopagnosia ,Fixation (psychology) ,Self-face recognition ,Prosopagnosia ,Neuropsychology and Physiological Psychology ,Face ,Face (geometry) ,Female ,Face inversion ,Visual Fields ,Psychology ,Facial Recognition ,Psychomotor Performance ,030217 neurology & neurosurgery ,Cognitive psychology - Abstract
Objective Recent evidence showed that individuals with congenital face processing impairment (congenital prosopagnosia [CP]) are highly accurate when they have to recognize their own face (self-face advantage) in an implicit matching task, with a preference for the right-half of the self-face (right perceptual bias). Yet the perceptual strategies underlying this advantage are unclear. Here, we aimed to verify whether both the self-face advantage and the right perceptual bias emerge in an explicit task, and whether those effects are linked to a different scanning strategy between the self-face and unfamiliar faces. Method Eye movements were recorded from 7 CPs and 13 controls, during a self/other discrimination task of stimuli depicting the self-face and another unfamiliar face, presented upright and inverted. Results Individuals with CP and controls differed significantly in how they explored faces. In particular, compared with controls, CPs used a distinct eye movement sampling strategy for processing inverted faces, by deploying significantly more fixations toward the nose and mouth areas, which resulted in more efficient recognition. Moreover, the results confirmed the presence of a self-face advantage in both groups, but the eye movement analyses failed to reveal any differences in the exploration of the self-face compared with the unfamiliar face. Finally, no bias toward the right-half of the self-face was found. Conclusions Our data suggest that the self-face advantage emerges both in implicit and explicit recognition tasks in CPs as much as in good recognizers, and it is not linked to any specific visual exploration strategies. (PsycINFO Database Record
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- 2018
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109. What do eye movements tell us about the visual perception of individuals with congenital prosopagnosia?
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Andrea Albonico, Roberta Daini, Manuela Malaspina, Carlo Toneatto, Malaspina, M, Albonico, A, Toneatto, C, and Daini, R
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Scan pattern ,Adult ,Male ,Eye movement ,Visual perception ,Eye Movements ,genetic structures ,Population ,M-PSI/02 - PSICOBIOLOGIA E PSICOLOGIA FISIOLOGICA ,Facial recognition system ,050105 experimental psychology ,Young Adult ,03 medical and health sciences ,0302 clinical medicine ,Arts and Humanities (miscellaneous) ,Humans ,0501 psychology and cognitive sciences ,Face recognition ,education ,education.field_of_study ,Social perception ,05 social sciences ,Cognitive neuroscience of visual object recognition ,Congenital prosopagnosia ,Object recognition ,Gaze ,Prosopagnosia ,Neuropsychology and Physiological Psychology ,Pattern Recognition, Visual ,Social Perception ,Female ,M-PSI/01 - PSICOLOGIA GENERALE ,Psychology ,Facial Recognition ,030217 neurology & neurosurgery ,Cognitive psychology - Abstract
Objective The lack of inversion effect for face recognition in congenital prosopagnosia (CP) is consistent with the hypothesis of a failure in holistic processing. However, although CPs' abnormal gaze behavior for upright faces has already been demonstrated, neither their scanning strategy for inverted faces, nor the possibility that their abnormal gaze behavior with upright faces is because of reasons other than the holistic deficit have been investigated yet. Method We recorded the eye movements of a congenital prosopagnosic and a control group during the encoding of unknown faces, objects, and flowers. Two types of stimuli (faces and objects) were presented upright and inverted. Results CPs explored upright and inverted faces in the same way (i.e., similar number of fixations of the same duration and similarly distributed), whereas controls increased the number of fixations and their duration during the presentation of inverted faces. By contrast, the 2 groups showed a similar inversion effect during the encoding of objects. Finally, CPs showed anomalous exploration of within-class objects (i.e., flowers) and impairment in subordinate-level object discrimination. Conclusions Our results demonstrate that: (a) CPs use the same part-based strategy in encoding both upright and inverted faces, suggesting a possible interpretation of the lack of inversion effect in this population; (b) CPs' lack of inversion effect is face-specific and does not affect objects; (c) however, CPs' deficit seems not to be limited to faces, and to extend to individual-item recognition within a class. (PsycINFO Database Record
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- 2017
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110. Impact of screening programme using the faecal immunochemical test on stage of colorectal cancer: Results from the IMPATTO study
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Vicentini, Massimo, Zorzi, Manuel, Bovo, Emanuela, Mancuso, Pamela, Zappa, Marco, Manneschi, Gianfranco, Mangone, Lucia, Rossi, Paolo Giorgi, Grazzini, Grazia, Mantellini, Paola, Caldarella, Adele, Intrieri, Teresa, Anghinoni, Emanuela, Senore, Carlo, Tisano, Francesco, Ziino, Antonio Colanino, Malignaggi, Sabina, Passanisi, Guido, Rugge, Massimo, Turrin, Anna, Piffer, Silvano, Gentilini, Maria, Rizzello, Roberto, Pertile, Riccardo, Sensi, Flavio, Cesaraccio, Rosaria, Interieri, Teresa, Ferretti, Stefano, Collina, Natalina, Petrucci, Chiara, Fanetti, Anna Clara, Cecconami, Lorella, Fusco, Mario, Vitale, Maria Francesca, Castaing, Marine, Ippolito, Antonella, Varvara, Massimo, Pesce, Paola, Filiberti, Rosa, Borciani, Elisabetta, Seghini, Pietro, Stracci, Fabrizio, Malaspina, Morena, Serraino, Diego, Falcini, Fabio, Giuliani, Orietta, Pannozzo, Fabio, Curatella, Simonetta, Calabretta, Francesca, Bellardini, Paola, Carrozzi, Giuliano, Bisanti, Luigi, Russo, Antonio Giampiero, Silvestri, Anna Rita, Tidone, Enrica, Giacomin, Adriano, Azzoni, Alberto, Mazzucco, Walter, Cusimano, Rosanna, Campari, Cinzia, Caroli, Stefania, Michiara, Maria, Sgargi, Paolo, De Togni, Aldo, Palmonari, Caterina, Casella, Claudia, Puppo, Antonella, Vicentini M., Zorzi M., Bovo E., Mancuso P., Zappa M., Manneschi G., Mangone L., Rossi P.G., Grazzini G., Mantellini P., Caldarella A., Intrieri T., Anghinoni E., Senore C., Tisano F., Ziino A.C., Malignaggi S., Passanisi G., Rugge M., Turrin A., Piffer S., Gentilini M., Rizzello R., Pertile R., Sensi F., Cesaraccio R., Interieri T., Ferretti S., De Togni A., Palmonari C., Collina N., Petrucci C., Fanetti A.C., Cecconami L., Fusco M., Vitale M.F., Castaing M., Ippolito A., VarvarA M., Pesce P., Filiberti R., Casella C., Puppo A., Borciani E., Seghini P., Stracci F., Malaspina M., Serraino D., Falcini F., Giuliani O., Pannozzo F., Curatella S., Calabretta F., Bellardini P., Carrozzi G., Bisanti L., Russo A.G., Silvestri A.R., Tidone E., Giacomin A., Azzoni A., Mazzucco W., Cusimano R., Campari C., Caroli S., Michiara M., and Sgargi P.
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Male ,Cancer Research ,medicine.medical_specialty ,Colorectal cancer ,Prevalence ,Socio-culturale ,Colonoscopy ,Colorectal Neoplasm ,Settore MED/42 - Igiene Generale E Applicata ,colorectal cancer screening ,Screening programme ,Feces ,03 medical and health sciences ,0302 clinical medicine ,colonoscopy ,Faecal immunochemical test, colonoscopy, colorectal cancer screening, epidemiology, cancer registries ,Internal medicine ,Epidemiology ,medicine ,Humans ,Stage (cooking) ,Early Detection of Cancer ,Aged ,Neoplasm Staging ,Proportional Hazards Models ,cancer registrie ,medicine.diagnostic_test ,Faecal immunochemical test ,business.industry ,Incidence (epidemiology) ,Incidence ,Middle Aged ,medicine.disease ,Immunohistochemistry ,Oncology ,Italy ,cancer registries ,030220 oncology & carcinogenesis ,Relative risk ,Occult Blood ,epidemiology ,Fece ,Female ,Neoplasm Grading ,Colorectal Neoplasms ,business ,Human - Abstract
To evaluate the impact of faecal immunochemical test (FIT) screening on stage distribution at diagnosis, and to estimate relative incidence rates by stage in screened at first and subsequent rounds vs. unscreened. We included all incident cases occurring in 2000-2008 in 50- to 71-year-olds residing in areas with an FIT-screening programme. Multinomial logistic models were computed to estimate the relative risk ratio (RRR) of stages I and IV, compared to stage II + III, adjusting for age, sex, geographical area, and incidence year. Proportions were then used to estimate incidence rate ratios (IRR) by stage for screened subjects at the first and at subsequent rounds vs. unscreened subjects, applying the expected changes in overall incidence during screening phases. 11,663 cancers were included: 5965 in not-invited and 5,698 in invited subjects, 3,425 of whom attendees. Compared to not-invited, invited subjects had RRR 2.04 (95% CI: 1.84; 2.46) of stage I and RRR 0.77 (95% CI: 0.69; 0.87) of stage IV. Differences were stronger comparing attendees vs. nonattendees. Interval cancers were more frequently stage I compared to non-invited (RRR 1.54; 95% CI: 1.15; 2.04), but there was no difference for stage IV. IRRs in screened at first round vs. unscreened were 4.6 (95% CI: 4.2; 5.1), 1.4 (95% CI: 1.3; 1.5) and 0.7 (95% CI: 0.6; 0.9) for stages I, II + III and IV, respectively; in the following rounds the IRRs of screened vs. unscreened were 1.4 (95% CI: 1.2; 1.6), 0.8 (95% CI: 0.7; 0.9) and 0.3 (95% CI: 0.1; 0.4) for stages I, II + III and IV, respectively. FIT screening reduces the incidence of metastatic cancers by about 70% after the first round.
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- 2019
111. Right perceptual bias and self-face recognition in individuals with congenital prosopagnosia
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Roberta Daini, Manuela Malaspina, Andrea Albonico, Malaspina, M, Albonico, A, and Daini, R
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Male ,Memory Test ,Face perception ,Right-Hemisphere ,media_common.quotation_subject ,Face matching ,Neuropsychological Tests ,Facial recognition system ,Functional Laterality ,Judgment ,Young Adult ,self-face recognition ,Arts and Humanities (miscellaneous) ,Perception ,Chimeric-Face ,Humans ,left perceptual bia ,Right hemisphere ,Memory test ,self-face advantage ,General Psychology ,media_common ,Developmental Prosopagnosia ,Processing Facial Emotion ,Eye-Movement Pattern ,Recognition, Psychology ,General Medicine ,Self Concept ,Reading Habit ,Visual field ,Prosopagnosia ,Scanning Habit ,Pattern Recognition, Visual ,Face ,Split-Brain ,Female ,Visual Fields ,Asymmetrie ,Psychology ,Photic Stimulation ,congenital prosopagnosia ,Cognitive psychology - Abstract
The existence of a drift to base judgments more on the right half-part of facial stimuli, which falls in the observer's left visual field (left perceptual bias (LPB)), in normal individuals has been demonstrated. However, less is known about the existence of this phenomenon in people affected by face impairment from birth, namely congenital prosopagnosics. In the current study, we aimed to investigate the presence of the LPB under face impairment conditions using chimeric stimuli and the most familiar face of all: the self-face. For this purpose we tested 10 participants with congenital prosopagnosia and 21 healthy controls with a face matching task using facial stimuli, involving a spatial manipulation of the left and the right hemi-faces of self-photos and photos of others. Even though congenital prosopagnosics performance was significantly lower than that of controls, both groups showed a consistent self-face advantage. Moreover, congenital prosopagnosics showed optimal performance when the right side of their face was presented, that is, right perceptual bias, suggesting a differential strategy for self-recognition in those subjects. A possible explanation for this result is discussed.
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- 2015
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112. Target Type Modulates the Effect of Task Demand on Reflexive Focal Attention
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Andrea Albonico, Roberta Daini, Manuela Malaspina, Albonico, A, Malaspina, M, and Daini, R
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Cognitive Neuroscience ,Target type ,detection ,M-PSI/02 - PSICOBIOLOGIA E PSICOLOGIA FISIOLOGICA ,050105 experimental psychology ,Article ,Task (project management) ,03 medical and health sciences ,0302 clinical medicine ,focal attention ,spatial attention ,central vision ,reflexive attention ,discrimination ,Foveal ,Reflexivity ,0501 psychology and cognitive sciences ,Computer vision ,business.industry ,05 social sciences ,Cell Biology ,Sensory Systems ,Ophthalmology ,Task demand ,Central vision ,Focusing attention ,Artificial intelligence ,Psychology ,business ,M-PSI/01 - PSICOLOGIA GENERALE ,030217 neurology & neurosurgery ,Optometry ,Cognitive psychology - Abstract
Focusing attention on a limited space within the environment allows us to concentrate our resources selectively on that location while ignoring the rest of the space. In this study we investigated how the deployment of the focal attention in foveal vision can be affected by task and stimuli specificity. In particular, we measured the cue-size effect in four experiments: shape detection (Experiment 1), shape discrimination (Experiment 2), letter detection (Experiment 3), and letter discrimination (Experiment 4). Our results highlight that, although the focal component can be elicited by different tasks (i.e., detection or discrimination) and by using different types of stimuli (i.e., shapes or letters), those effects interact with each other. Specifically, the effect of focal attention is more noticeable when letter stimuli are used in the case of a detection task, while no difference between letters and geometrical shapes is observed in the discrimination task. Furthermore, the analysis of the cue-size effect across the four experiments confirmed that the deployment of focal attention in foveal vision is mainly reflexive.
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- 2017
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113. Italian normative data and validation of two neuropsychological tests of face recognition: Benton Facial Recognition Test and Cambridge Face Memory Test
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Roberta Daini, Manuela Malaspina, Andrea Albonico, Albonico, A, Malaspina, M, and Daini, R
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Adult ,Male ,Face (sociological concept) ,Cambridge Face Memory Test ,Dermatology ,Neuropsychological Tests ,Facial recognition system ,050105 experimental psychology ,Benton Facial Recognition Test ,03 medical and health sciences ,Young Adult ,0302 clinical medicine ,Reference Values ,Humans ,0501 psychology and cognitive sciences ,Face recognition ,Memory test ,05 social sciences ,Neuropsychology ,Contrast (statistics) ,Congenital prosopagnosia ,General Medicine ,Neuropsychological test ,Face discrimination ,Psychiatry and Mental health ,Prosopagnosia ,Italy ,Normative ,Female ,Neurology (clinical) ,Psychology ,Facial recognition test ,Facial Recognition ,030217 neurology & neurosurgery ,Cognitive psychology - Abstract
The Benton Facial Recognition Test (BFRT) and Cambridge Face Memory Test (CFMT) are two of the most common tests used to assess face discrimination and recognition abilities and to identify individuals with prosopagnosia. However, recent studies highlighted that participant-stimulus match ethnicity, as much as gender, has to be taken into account in interpreting results from these tests. Here, in order to obtain more appropriate normative data for an Italian sample, the CFMT and BFRT were administered to a large cohort of young adults. We found that scores from the BFRT are not affected by participants' gender and are only slightly affected by participant-stimulus ethnicity match, whereas both these factors seem to influence the scores of the CFMT. Moreover, the inclusion of a sample of individuals with suspected face recognition impairment allowed us to show that the use of more appropriate normative data can increase the BFRT efficacy in identifying individuals with face discrimination impairments; by contrast, the efficacy of the CFMT in classifying individuals with a face recognition deficit was confirmed. Finally, our data show that the lack of inversion effect (the difference between the total score of the upright and inverted versions of the CFMT) could be used as further index to assess congenital prosopagnosia. Overall, our results confirm the importance of having norms derived from controls with a similar experience of faces as the "potential" prosopagnosic individuals when assessing face recognition abilities.
- Published
- 2017
114. Investigating face-specificity through congenital prosopagnosia: studies on perceptual phenomena and eye movement patterns
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MALASPINA, MANUELA, Malaspina, M, and DAINI, ROBERTA
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Prosopagnosia, Self recognition, Eye movements ,M-PSI/01 - PSICOLOGIA GENERALE - Abstract
Congenital prosopagnosia consists of the failure to develop normal face recognition ability despite intact low-level perceptual and intellectual functioning, and in the context of normal exposure to faces throughout the individual’s life. Typically, these individuals are able to perceive facial stimuli as faces but fail to identify a face as familiar or unfamiliar and to identify it. Despite the large amount of studies that have investigated face recognition in individuals with typical development and in congenital prosopagnosics over the last twenty years, we are still far from a complete understanding of the mechanisms underlying typical and atypical face recognition, and some research questions are still open. For this reason, the present dissertation investigates some perceptual effects in individuals with a selective deficit in face recognition processing in order to reach a better understanding of what happens during a successful and unsuccessful face recognition process. In particular, by using a combination of behavioural and eye-tracking methods, I investigated whether the left perceptual bias and the self-face advantage are shown by individuals with congenital prosopagnosia and are truly face-specific or not. My results demonstrate that, whereas the left perceptual bias seems to characterize the recognition of unfamiliar faces in good recognizers, individuals with congenital prosopagnosia seem to show an opposite bias (i.e., a right perceptual bias) during the recognition of the self-face. Moreover, despite their face recognition impairment, congenital prosopagnosics consistently show high accuracy in recognizing their own face (i.e., a self-face advantage). Furthermore, some of the studies I conducted on the visual scanning strategies of this population demonstrated that the self-face advantage phenomenon is not associated with a different exploration of the face stimuli, suggesting that it could reflect a more general self-advantage and not be face-specific. Finally, the evidence presented in this dissertation also highlights that individuals with face impairment from birth show some difficulties in recognizing stimuli with high degree of similarity (such as objects belonging to the same class), and that these difficulties are associated with a different pattern of visual exploration. Overall, the evidence illustrated in the present thesis helps to shed light on the mechanisms characterizing face recognition and to expand our knowledge on the impairment affecting individuals with congenital prosopagnosia.
- Published
- 2017
115. Do people have insight into their face recognition abilities?
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Roberta Daini, Bronwyn Hall, Libby Taylor, Andrea Albonico, Manuela Malaspina, Renaud Laguesse, Davide Rivolta, Gillian Rhodes, Shahd Al-Janabi, Romina Palermo, Tolga Tez, Elinor McKone, Jessica Irons, Bruno Rossion, Palermo, R, Rossion, B, Rhodes, G, Laguesse, R, Tez, T, Hall, B, Albonico, A, Malaspina, M, Daini, R, Irons, J, Al Janabi, S, Taylor, L, Rivolta, D, and Mckone, E
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Adult ,Male ,Psychology (all) ,Adolescent ,Face perception ,Physiology ,Metacognition ,Face (sociological concept) ,Experimental and Cognitive Psychology ,Neuropsychological Tests ,Individual difference ,Facial recognition system ,050105 experimental psychology ,Developmental psychology ,Young Adult ,03 medical and health sciences ,0302 clinical medicine ,Surveys and Questionnaires ,Physiology (medical) ,Neuropsychologia ,Self-evaluation ,medicine ,Humans ,0501 psychology and cognitive sciences ,Neuropsychological assessment ,Memory test ,General Psychology ,Accuracy ,medicine.diagnostic_test ,05 social sciences ,Recognition, Psychology ,General Medicine ,Middle Aged ,Test (assessment) ,Prosopagnosia ,Neuropsychology and Physiological Psychology ,Pattern Recognition, Visual ,Face ,Female ,Self Report ,Psychology ,Photic Stimulation ,030217 neurology & neurosurgery ,Cognitive psychology - Abstract
Diagnosis of developmental or congenital prosopagnosia (CP) involves self-report of everyday face recognition difficulties, which are corroborated with poor performance on behavioural tests. This approach requires accurate self-evaluation. We examine the extent to which typical adults have insight into their face recognition abilities across four experiments involving nearly 300 participants. The experiments used five tests of face recognition ability: two that tap into the ability to learn and recognize previously unfamiliar faces [the Cambridge Face Memory Test, CFMT; Duchaine, B., & Nakayama, K. (2006). The Cambridge Face Memory Test: Results for neurologically intact individuals and an investigation of its validity using inverted face stimuli and prosopagnosic participants. Neuropsychologia, 44(4), 576–585. doi:10.1016/j.neuropsychologia.2005.07.001; and a newly devised test based on the CFMT but where the study phases involve watching short movies rather than viewing static faces—the CFMT-Films] and three that tap face matching [Benton Facial Recognition Test, BFRT; Benton, A., Sivan, A., Hamsher, K., Varney, N., & Spreen, O. (1983). Contribution to neuropsychological assessment. New York: Oxford University Press; and two recently devised sequential face matching tests]. Self-reported ability was measured with the 15-item Kennerknecht et al. questionnaire [Kennerknecht, I., Ho, N. Y., & Wong, V. C. (2008). Prevalence of hereditary prosopagnosia (HPA) in Hong Kong Chinese population. American Journal of Medical Genetics Part A, 146A(22), 2863–2870. doi:10.1002/ajmg.a.32552]; two single-item questions assessing face recognition ability; and a new 77-item meta-cognition questionnaire. Overall, we find that adults with typical face recognition abilities have only modest insight into their ability to recognize faces on behavioural tests. In a fifth experiment, we assess self-reported face recognition ability in people with CP and find that some people who expect to perform poorly on behavioural tests of face recognition do indeed perform poorly. However, it is not yet clear whether individuals within this group of poor performers have greater levels of insight (i.e., into their degree of impairment) than those with more typical levels of performance.
- Published
- 2017
116. Geospatial analysis of the influence of family doctor on colorectal cancer screening adherence
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Alessio Gili, Basilio Passamonti, Fortunato Bianconi, Giulia Naldini, Fabrizio Stracci, Morena Malaspina, Vincenza Gianfredi, Stracci, F., Gili, A., Naldini, G., Gianfredi, V., Malaspina, M., Passamonti, B., and Bianconi, F.
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Male ,European People ,Colorectal cancer ,Psychological intervention ,0302 clinical medicine ,Cancer screening ,Medicine and Health Sciences ,Ethnicities ,Mass Screening ,Public and Occupational Health ,030212 general & internal medicine ,Geographic Areas ,education.field_of_study ,Multidisciplinary ,Geography ,Physicians, Family ,Colonoscopy ,Middle Aged ,Socioeconomic Aspects of Health ,Italian People ,Oncology ,Italy ,Research Design ,030220 oncology & carcinogenesis ,Medicine ,Female ,Colorectal Neoplasms ,Cancer Screening ,Research Article ,Census ,medicine.medical_specialty ,Aged ,Humans ,Patient Compliance ,Sex Factors ,Physician-Patient Relations ,Science ,Population ,MEDLINE ,Research and Analysis Methods ,03 medical and health sciences ,Diagnostic Medicine ,Physicians ,Environmental health ,Cancer Detection and Diagnosis ,medicine ,Family ,education ,Socioeconomic status ,Mass screening ,Colorectal Cancer ,Survey Research ,Public health ,Cancers and Neoplasms ,medicine.disease ,Health Care ,Age Groups ,People and Places ,Earth Sciences ,Population Groupings - Abstract
BackgroundDespite the well-recognised relevance of screening in colorectal cancer (CRC) control, adherence to screening is often suboptimal. Improving adherence represents an important public health strategy. We investigated the influence of family doctors (FDs) as determinant of CRC screening adherence by comparing each FDs practice participation probability to that of the residents in the same geographic areas using the whole population geocoded.MethodsWe used multilevel logistic regression model to investigate factors associated with CRC screening adherence, among 333,843 people at their first screening invitation. Standardized Adherence Rates (SAR) by age, gender, and socioeconomic status were calculated comparing FDs practices to the residents in the same geographic areas using geocoded target population.ResultsScreening adherence increased from 41.0% (95% CI, 40.8-41.2) in 2006-2008 to 44.7% (95% CI, 44.5-44.9) in 2011-2012. Males, the most deprived and foreign-born people showed low adherence. FD practices and the percentage of foreign-born people in a practice were significant clustering factors. SAR for 145 (21.4%) FDs practices differed significantly from people living in the same areas. Predicted probabilities of adherence were 31.7% and 49.0% for FDs with low and high adherence, respectively.DiscussionFDs showed a direct and independent effect to the CRC screening adherence of the people living in their practice. FDs with significantly high adherence level could be the key to adherence improvement.ImpactMost deprived individuals and foreigners represent relevant targets for interventions in public health aimed to improve CRC screening adherence.
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- 2019
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117. Congenital prosopagnosia is associated with a genetic variation in the oxytocin receptor (OXTR) gene: An exploratory study
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Zaira Cattaneo, Mariarita Lillo, Federico Manai, Susanna Schiavi, Sergio Comincini, Boris Suchan, Valentina Fermi, Roberta Daini, Manuela Malaspina, Cattaneo, Z, Daini, R, Malaspina, M, Manai, F, Lillo, M, Fermi, V, Schiavi, S, Suchan, B, and Comincini, S
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Adult ,Male ,Adolescent ,Genotyping Techniques ,Population ,face blindness ,Single-nucleotide polymorphism ,Neuropsychological Tests ,Polymorphism, Single Nucleotide ,050105 experimental psychology ,Cohort Studies ,03 medical and health sciences ,Young Adult ,0302 clinical medicine ,Polymorphism (computer science) ,Germany ,Genetic variation ,Cluster Analysis ,Humans ,0501 psychology and cognitive sciences ,Genetic Predisposition to Disease ,Young adult ,education ,Genetic Association Studies ,Congenital prosopagnosia ,oxytocin receptor gene ,congenital prosopagnosia ,Genetic association ,Genetics ,education.field_of_study ,face blindne ,General Neuroscience ,05 social sciences ,Middle Aged ,Oxytocin receptor ,Prosopagnosia ,Settore M-PSI/02 - Psicobiologia e Psicologia Fisiologica ,Italy ,Receptors, Oxytocin ,Female ,Psychology ,Facial Recognition ,030217 neurology & neurosurgery ,Cohort study - Abstract
Face-recognition deficits, referred to with the term prosopagnosia (i.e., face blindness), may manifest during development in the absence of any brain injury (from here the term congenital prosopagnosia, CP). It has been estimated that approximately 2.5% of the population is affected by face-processing deficits not depending on brain lesions, and varying a lot in severity. The genetic bases of this disorder are not known. In this study we tested for genetic association between single-nucleotide polymorphisms (SNPs) in the oxytocin receptor gene (OXTR) and CP in a restricted cohort of Italian participants. We found evidence of an association between the common genetic variants rs53576 and rs2254298 OXTR SNPs and prosopagnosia. This association was also found when including an additional group of German individuals classified as prosopagnosic in the analysis. Our preliminary data provide initial support for the involvement of genetic variants of OXTR in a relevant cognitive impairment, whose genetic bases are still largely unexplored.
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- 2016
118. Temporal dissociation between the focal and orientation components of spatial attention in central and peripheral vision
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Emanuela Bricolo, Marialuisa Martelli, Manuela Malaspina, Andrea Albonico, Roberta Daini, Albonico, A, Malaspina, M, Bricolo, E, Martelli, M, and Daini, R
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vision ,Dissociation (neuropsychology) ,selective attention ,Relative weight ,Stimulus (physiology) ,050105 experimental psychology ,orientation ,ocular ,03 medical and health sciences ,arts and humanities (miscellaneous) ,0302 clinical medicine ,male ,experimental and cognitive psychology ,spatial attention ,peripheral vision ,0501 psychology and cognitive sciences ,Selective attention ,developmental and educational psychology ,humans ,Orientation, Spatial ,Vision, Ocular ,reaction time ,Communication ,photic stimulation ,business.industry ,adult ,05 social sciences ,focal attention ,cues ,General Medicine ,attention ,space perception ,spatial ,female ,Peripheral vision ,central vision ,orientation of attention ,orientation, spatial ,psychomotor performance ,vision, ocular ,young adult ,Central vision ,business ,Psychology ,030217 neurology & neurosurgery ,Cognitive psychology - Abstract
Selective attention, i.e. the ability to concentrate one's limited processing resources on one aspect of the environment, is a multifaceted concept that includes different processes like spatial attention and its subcomponents of orienting and focusing. Several studies, indeed, have shown that visual tasks performance is positively influenced not only by attracting attention to the target location (orientation component), but also by the adjustment of the size of the attentional window according to task demands (focal component). Nevertheless, the relative weight of the two components in central and peripheral vision has never been studied. We conducted two experiments to explore whether different components of spatial attention have different effects in central and peripheral vision. In order to do so, participants underwent either a detection (Experiment 1) or a discrimination (Experiment 2) task where different types of cues elicited different components of spatial attention: a red dot, a small square and a big square (an optimal stimulus for the orientation component, an optimal and a sub-optimal stimulus for the focal component respectively). Response times and cue-size effects indicated a stronger effect of the small square or of the dot in different conditions, suggesting the existence of a dissociation in terms of mechanisms between the focal and the orientation components of spatial attention. Specifically, we found that the orientation component was stronger in periphery, while the focal component was noticeable only in central vision and characterized by an exogenous nature.
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- 2016
119. Something in the way people move: the benefit of facial movements in face identification
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Manuela Malaspina, Andrea Albonico, Roberta Daini, Albonico, A, Malaspina, M, and Daini, R
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education.field_of_study ,Dissociation (neuropsychology) ,lcsh:BF1-990 ,Population ,famous face identification ,emotional expressions ,Facial recognition system ,facial dynamic features ,lcsh:Psychology ,Face perception ,typical facial expressions ,face perception ,Psychology ,Emotional expression ,Invariant (mathematics) ,ace perception, famous face identification, emotional expressions, typical facial expressions ,M-PSI/01 - PSICOLOGIA GENERALE ,education ,Social psychology ,General Psychology ,Original Research - Abstract
While the dissociation between invariant aspects of a face and emotional expressions has been studied extensively, the role of non-emotional changeable aspects in face recognition has been considered in the literature rarely. The purpose of the present study was to understand whether information on changeable aspects (with and without emotional content) can help those individuals with poor face recognition abilities (when based on invariant features) in recognizing famous faces. From a population of 80 university students we selected two groups of participants, one with poor performance (experimental group) and the other with good performance (control group). By means of a preliminary experiment, we selected videos of 16 Italian celebrities that were presented in three different conditions: motionless, with non-emotional expressions, and with emotional expressions. While the control group did not differ in the three conditions, the experimental group showed a significantly better performance in the two conditions with facial movements, which did not differ between each other. These results suggest a role of changeable aspects in the identification of famous faces, rising only in the case invariant features are not analysed properly.
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- 2015
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120. Elaborazione delle espressioni facciali, emotive e non, in soggetti affetti da sindrome di Asperger o autismo ad alto funzionamento
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MALASPINA, MANUELA, ALBONICO, ANDREA, DAINI, ROBERTA, RICCIARDELLI, PAOLA, Malaspina, M, Albonico, A, Daini, R, and Ricciardelli, P
- Subjects
Asperger syndrome, High-Functioning Autism, Face recognition, Emotional expressions, Non-emotional expressions - Abstract
The aim of the present study was to investigate the processing of the emotional and non-emotional facial expression and facial features of unfamiliar faces in individuals with Asperger's syndrome (AS) and High-Functioning Autism (HFA). To this end, we tested 14 Adults with AS and HFA and 12 typically developing individuals, matched for age and education level, in a recognition task of faces in which internal features (e.g., eyes size), emotional and non-emotional facial expressions could or could not have been manipulated. Participants were asked first to undergo the recognition task and then a change detection task of the manipulation. Results show not only a face recognition impairment (lower accuracy) in the autistic group, but also a difference in the processing of facial changeable and unchangeable features, and between emotional and non-emotional expressions.
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- 2014
121. Differential effects of the size of the attentional window in central and peripheral vision
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ALBONICO, ANDREA, MALASPINA, MANUELA, BRICOLO, EMANUELA, DAINI, ROBERTA, Martelli, M, Albonico, A, Malaspina, M, Bricolo, E, Martelli, M, and Daini, R
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Attention, Spatial Vision, Behavioural Measurements - Published
- 2014
122. L’io è diverso dall’altro? Uno studio sui movimenti oculari nella Prosopagnosia Congenita
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MALASPINA, MANUELA, ALBONICO, ANDREA, DAINI, ROBERTA, Malaspina, M, Albonico, A, and Daini, R
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Congenital Prosopagnosia, Self-Recognition, Eye-Movements - Published
- 2014
123. Dissociazione tra la componente selettiva e la componente focale dell’attenzione visuo-spaziale in visione centrale e periferica
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ALBONICO, ANDREA, MALASPINA, MANUELA, BRICOLO, EMANUELA, DAINI, ROBERTA, Martelli, M, Albonico, A, Malaspina, M, Bricolo, E, Martelli, M, and Daini, R
- Subjects
M-PSI/01 - PSICOLOGIA GENERALE ,Attenzione focale, visione centrale, visione periferica - Published
- 2014
124. Is Congenital Prosopagnosics’ eye movements pattern specific in self compared to others’ faces discrimination?
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MALASPINA, MANUELA, ALBONICO, ANDREA, DAINI, ROBERTA, Malaspina, M, Albonico, A, and Daini, R
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Congenital Prosopagnosia, Self-Recognition, Eye-Movements - Published
- 2014
125. Dissociazione nell’efficacia della stimolazione optocinetica tra errori di omissione e sostituzione nella dislessia da neglect
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MALASPINA, MANUELA, ALBONICO, ANDREA, DAINI, ROBERTA, Martelli, M, Primativo, S, Arduini, LS, Malaspina, M, Albonico, A, Martelli, M, Primativo, S, Arduini, L, and Daini, R
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Dislessia da neglect, Stimolazione optocinetica, Errori di sostituzione, Errori di omissione - Published
- 2013
126. Subjective self-assessment of face recognition ability is only weakly related to objective measures of face recognition performance
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Renaud Laguesse, Elinor McKone, Elisabeth Taylor, Andrea Albonico, Bronwyn Hall, Gillian Rhodes, Bruno Rossion, Manuela Malaspina, Jessica Irons, Alexandra Charpentier, Romina Palermo, Tolga Tez, Roberta Daini, Laguesse, R, Tez, T, Hall, B, Irons, J, Mckone, E, Daini, R, Albonico, A, Malaspina, M, Taylor, E, Rhodes, G, Charpentier, A, Rossion, B, and Palermo, R
- Subjects
Self-assessment ,Ophthalmology ,Face recognition, Subjective self-assessment, Objective measures ,Psychology ,Facial recognition system ,Sensory Systems ,Cognitive psychology - Published
- 2013
127. Attentive Pop-out: spatial asymmetries in a visual search task
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ALBONICO, ANDREA, MALASPINA, MANUELA, BRICOLO, EMANUELA, DAINI, ROBERTA, Martelli, M, Albonico, A, Malaspina, M, Bricolo, E, Martelli, M, and Daini, R
- Subjects
Visual Search, Asymmetries, Attentive Pop-Out - Published
- 2013
128. Dissociation in optokinetic stimulation sensitivity between omission and substitution reading errors in neglect dyslexia
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Lisa S. Arduino, Andrea Albonico, Roberta Daini, Marialuisa Martelli, Silvia Primativo, Manuela Malaspina, Arduino, L, Albonico, A, Malaspina, M, Martelli, M, Primativo, S, and Daini, R
- Subjects
medicine.medical_specialty ,Eye movement ,Dissociation (neuropsychology) ,media_common.quotation_subject ,Audiology ,Unilateral spatial neglect ,Dual mechanism ,lcsh:RC321-571 ,Neglect ,Behavioral Neuroscience ,Neglect dyslexia ,medicine ,lcsh:Neurosciences. Biological psychiatry. Neuropsychiatry ,Biological Psychiatry ,Original Research ,media_common ,unilateral spatial neglect, neglect dyslexia, optokinetic stimulation ,eye movements ,Dyslexia ,medicine.disease ,Neuropsychological rehabilitation ,Psychiatry and Mental health ,Neuropsychology and Physiological Psychology ,Neurology ,Perceptual integration ,neglect dyslexia ,neuropsychological rehabilitation ,optokinetic stimulation ,unilateral spatial neglect ,Psychology ,Optokinetic stimulation ,Neuroscience - Abstract
Although omission and substitution errors in neglect dyslexia (ND) patients have always been considered as different manifestations of the same acquired reading disorder, recently, we proposed a new dual mechanism model. While omissions are related to the exploratory disorder which characterizes unilateral spatial neglect, substitutions are due to a perceptual integration mechanism. A consequence of this hypothesis is that specific training for omission-type ND patients would aim at restoring the oculo-motor scanning and should not improve reading in substitution-type ND. With this aim we administered an optokinetic stimulation to two brain-damaged patients with both unilateral spatial neglect and neglect dyslexia, MA and EP, who showed ND deficits mainly characterized by omissions and substitutions, respectively. MA also showed an impairment in oculo-motor behaviour with a non-reading task, while EP did not. The two patients presented a dissociation with respect to their sensitivity to optokinetic stimulation so that, as expected, MA was positively affected, while EP was not. Our results confirm a dissociation between the two mechanisms underlying omission and substitution reading errors in ND patients. Moreover, they suggest that such a dissociation could possibly be extendeds to the effectiveness of rehabilitative procedures, and that patients who mainly omit contralesional-sided letters would benefit from optokinetic stimulation.
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- 2013
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129. A new explanatory model of neglect
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Arduino, LS, Martelli, M, Primativo, S, De Luca, M, ALBONICO, ANDREA, MALASPINA, MANUELA, DAINI, ROBERTA, Arduino, L, Martelli, M, Primativo, S, De Luca, M, Albonico, A, Malaspina, M, and Daini, R
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unilateral spatial neglect, neglect dyslexia, reading, eye movements - Published
- 2013
130. Dislessia da neglect: l’attenzione focale spiega gli errori di sostituzione?
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ALBONICO, ANDREA, MALASPINA, MANUELA, BRICOLO, EMANUELA, DAINI, ROBERTA, Albonico, A, Malaspina, M, Bricolo, E, and Daini, R
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Dislessia da neglect, Attenzione focale, Sostituzioni, Omissioni - Published
- 2013
131. Right perceptual bias and self-face advantage in Congenital Prosopagnosics
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MALASPINA, MANUELA, ALBONICO, ANDREA, DAINI, ROBERTA, Malaspina, M, Albonico, A, and Daini, R
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Congenital Prosopagnosia, Self-Face Advantage, Right-Perceptual Bias - Published
- 2012
132. Changeable and invariant aspects of face processing in Congenital Prosopagnosia
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ALBONICO, ANDREA, MALASPINA, MANUELA, DAINI, ROBERTA, Albonico, A, Malaspina, M, and Daini, R
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Congenital Prosopagnosia, Famous face recognition, Facial movements - Published
- 2012
133. Prosopagnosia congenita: che cosa può dirci sul riconoscimento di volti?
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DAINI, ROBERTA, ALBONICO, ANDREA, MALASPINA, MANUELA, Daini, R, Albonico, A, and Malaspina, M
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percezione visiva, riconoscimento di volti, prosopagnosia congenita - Published
- 2012
134. Congenital Prosopagnosia: The role of changeable and invariant aspects in famous face identification
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ALBONICO, ANDREA, MALASPINA, MANUELA, DAINI, ROBERTA, Albonico, A, Malaspina, M, and Daini, R
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Congenital Prosopagnosia, Famous face identification, Facial movements - Published
- 2012
135. Planck pre-launch status:Design and description of the Low Frequency Instrument
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M. Bersanelli, N. Mandolesi, R. C. Butler, A. Mennella, F. Villa, B. Aja, E. Artal, E. Artina, C. Baccigalupi, M. Balasini, G. Baldan, A. Banday, P. Bastia, P. Battaglia, T. Bernardino, E. Blackhurst, L. Boschini, C. Burigana, G. Cafagna, B. Cappellini, F. Cavaliere, F. Colombo, G. Crone, F. Cuttaia, O. D'Arcangelo, L. Danese, R. D. Davies, R. J. Davis, L. De Angelis, G. C. De Gasperis, L. De La Fuente, A. De Rosa, G. De Zotti, M. C. Falvella, F. Ferrari, R. Ferretti, L. Figini, S. Fogliani, C. Franceschet, E. Franceschi, T. Gaier, S. Garavaglia, F. Gomez, K. Gorski, A. Gregorio, P. Guzzi, J. M. Herreros, S. R. Hildebrandt, R. Hoyland, N. Hughes, M. Janssen, P. Jukkala, D. Kettle, V. H. Kilpiä, M. Laaninen, P. M. Lapolla, C. R. Lawrence, D. Lawson, J. P. Leahy, R. Leonardi, P. Leutenegger, S. Levin, P. B. Lilje, S. R. Lowe, P. M. Lubin, D. Maino, M. Malaspina, M. Maris, J. Marti-Canales, E. Martinez-Gonzalez, A. Mediavilla, P. Meinhold, M. Miccolis, G. Morgante, P. Natoli, R. Nesti, L. Pagan, C. Paine, B. Partridge, J. P. Pascual, F. Pasian, D. Pearson, M. Pecora, F. Perrotta, P. Platania, M. Pospieszalski, T. Poutanen, M. Prina, R. Rebolo, N. Roddis, J. A. Rubiño-Martin, M. J. Salmon, M. Sandri, M. Seiffert, R. Silvestri, A. Simonetto, P. Sjoman, G. F. Smoot, C. Sozzi, L. Stringhetti, E. Taddei, J. Tauber, L. Terenzi, M. Tomasi, J. Tuovinen, L. Valenziano, J. Varis, N. Vittorio, L. A. Wade, A. Wilkinson, F. Winder, A. Zacchei, A. Zonca, APC - Cosmologie, AstroParticule et Cosmologie (APC (UMR_7164)), Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3), PLANCK, Universidad de Cantabria, Bersanelli, M, Mandolesi, N, BUTLER R., C, Mennella, A, Villa, F, Aja, B, Artal, E, Artina, E, Baccigalupi, C, Balasini, M, Baldan, G, Banday, A, Bastia, P, Battaglia, P, Bernardino, T, Blackhurst, E, Boschini, L, Burigana, C, Cafagna, G, Cappellini, B, Cavaliere, F, Colombo, F, Crone, G, Cuttaia, F, Darcangelo, O, Danese, L, DAVIES R., D, DAVIS R., J, DE ANGELIS, L, DE GASPERIS G., C, DE LA FUENTE, L, DE ROSA, A, DE ZOTTI, G, FALVELLA M., C, Ferrari, F, Ferretti, R, Figini, L, Fogliani, S, Franceschet, C, Franceschi, E, Gaier, T, Garavaglia, S, Gomez, F, Gorski, K, Gregorio, Anna, Guzzi, P, HERREROS J., M, HILDEBRANDT S., R, Hoyland, R, Hughes, N, Janssen, M, Jukkala, P, Kettle, D, KILPIA V., H, Laaninen, M, LAPOLLA P., M, LAWRENCE C., R, Lawson, D, LEAHY J., P, Leonardi, R, Leutenegger, P, Levin, S, LILJE P., B, LOWE S., R, LUBIN P., M, Maino, D, Malaspina, M, Maris, M, MARTI CANALES, J, MARTINEZ GONZALEZ, E, Mediavilla, A, Meinhold, P, Miccolis, M, Morgante, G, Natoli, P, Nesti, R, Pagan, L, Paine, C, Partridge, B, PASCUAL J., P, Pasian, F, Pearson, D, Pecora, M, Perrotta, F, Platania, P, Pospieszalski, M, Poutanen, T, Prina, M, Rebolo, R, Roddis, N, RUBINO MARTIN J., A, SALMON M., J, Sandri, M, Seiffert, M, Silvestri, R, Simonetto, A, Sjoman, P, SMOOT G., F, Sozzi, C, Stringhetti, L, Taddei, E, Tauber, J, Terenzi, L, Tomasi, M, Tuovinen, J, Valenziano, L, Varis, J, Vittorio, N, WADE L., A, Wilkinson, A, Winder, F, Zacchei, A, Zonca, A., Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Observatoire de Paris, PSL Research University (PSL)-PSL Research University (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Observatoire de Paris, PSL Research University (PSL)-PSL Research University (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Physique Corpusculaire et Cosmologie - Collège de France (PCC), Collège de France (CdF)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Collège de France (CdF)-Centre National de la Recherche Scientifique (CNRS), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Observatoire de Paris, and Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)
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detectors – instrumentation ,Computer science ,[SDU.ASTR.CO]Sciences of the Universe [physics]/Astrophysics [astro-ph]/Cosmology and Extra-Galactic Astrophysics [astro-ph.CO] ,Cosmic microwave background ,cosmic microwave background ,cosmology: observations ,space vehicles: instruments ,01 natural sciences ,7. Clean energy ,CMB physics ,observations [Cosmology] ,010303 astronomy & astrophysics ,Planck ESA mission ,Astrophysics::Instrumentation and Methods for Astrophysics ,Polarization (waves) ,symbols ,Radiometric dating ,Astrophysics - Instrumentation and Methods for Astrophysics ,Astrophysics - Cosmology and Nongalactic Astrophysics ,Cosmology and Nongalactic Astrophysics (astro-ph.CO) ,FOS: Physical sciences ,Low frequency ,Radio spectrum ,instruments – instrumentation [cosmic microwave background – telescopes – space vehicles] ,[PHYS.ASTR.CO]Physics [physics]/Astrophysics [astro-ph]/Cosmology and Extra-Galactic Astrophysics [astro-ph.CO] ,instruments [Space vehicles] ,symbols.namesake ,Settore FIS/05 - Astronomia e Astrofisica ,0103 physical sciences ,Electronic engineering ,Calibration ,Black-body radiation ,Sensitivity (control systems) ,Planck ,Instrumentation and Methods for Astrophysics (astro-ph.IM) ,cosmic microwave background – telescopes – space vehicles: instruments – instrumentation ,Radiometer ,cosmology-observations ,010308 nuclear & particles physics ,Amplifier ,Astronomy and Astrophysics ,polarimeters – submillimeter ,Space and Planetary Science ,general ,space vehicles-instruments ,Microwave - Abstract
21 páginas, 23 figuras, 13 tablas.-- et al., In this paper we present the Low Frequency Instrument (LFI), designed and developed as part of the Planck space mission, the ESA programme dedicated to precision imaging of the cosmic microwave background (CMB). Planck-LFI will observe the full sky in intensity and polarisation in three frequency bands centred at 30, 44 and 70 GHz, while higher frequencies (100–850 GHz) will be covered by the HFI instrument. The LFI is an array of microwave radiometers based on state-of-the-art indium phosphide cryogenic HEMT amplifiers implemented in a differential system using blackbody loads as reference signals. The front end is cooled to 20 K for optimal sensitivity and the reference loads are cooled to 4 K to minimise low-frequency noise. We provide an overview of the LFI, discuss the leading scientific requirements, and describe the design solutions adopted for the various hardware subsystems. The main drivers of the radiometric, optical, and thermal design are discussed, including the stringent requirements on sensitivity, stability, and rejection of systematic effects. Further details on the key instrument units and the results of ground calibration are provided in a set of companion papers., T.P.’s work was supported in part by the Academy of Finland grants 205800, 214598, 121703, and 121962. T.P. thanks the Waldemar von Frenckells Stiftelse, Magnus Ehrnrooth Foundation, and Väisälä Foundation for financial support. We acknowledge partial support from the NASA LTSA Grant NNG04CG90G.
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- 2010
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136. Planck pre-launch status:Calibration of the Low Frequency Instrument flight model radiometers
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Angel Colin, Davide Maino, Charles R. Lawrence, O. D'Arcangelo, Andrea Zonca, Jussi Varis, F. Pasian, Andrea Zacchei, R. Silvestri, Gianluca Morgante, M. J. Salmon, E. Franceschi, E. Blackhurst, M. Laaninen, D. Lawson, A. Simonetto, M. Sandri, S. R. Lowe, L. Pagan, F. Winder, S. Galeotta, L. de la Fuente, J. Edgeley, A. Mennella, M. Frailis, Althea Wilkinson, N. Hughes, J. P. Leahy, P. Sjoman, M. Balasini, F. Cuttaia, D. Kettle, V. H. Kilpiä, Anna Gregorio, A. Galtress, M. Pecora, M. Maris, P. Battaglia, Beatriz Aja, Eduardo Artal, Fabrizio Villa, P. Leutenegger, Roger J. Hoyland, Luca Valenziano, T. Poutanen, Luca Stringhetti, M. Miccolis, Peter Meinhold, N. Mandolesi, M. Tomasi, Marco Bersanelli, Marian Pospieszalski, Francesco Cavaliere, B. Cappellini, L. Mendes, P. Jukkala, Cristian Franceschet, Michael Seiffert, Carlo Sozzi, Juan Pablo Pascual, F. Colombo, L. Boschini, J. Tuovinen, A. Mediavilla, Steven Levin, N. Roddis, P. M. Lapolla, R. J. Davis, R. C. Butler, Rodrigo Leonardi, Todd Gaier, Luca Terenzi, M. Malaspina, T. Bernardino, Villa, F., Terenzi, L., Sandri, M., Meinhold, P., Poutanen, T., Battaglia, P., Franceschet, C., Hughes, N., Laaninen, M., Lapolla, P., Bersanelli, M., Butler, R. C., Cuttaia, F., D'Arcangelo, O., Frailis, M., Franceschi, E., Galeotta, S., Gregorio, Anna, Leonardi, R., Lowe, S. R., Mandolesi, N., Maris, M., Mendes, L., Mennella, A., Morgante, G., Stringhetti, L., Tomasi, M., Valenziano, L., Zacchei, A., Zonca, A., Aja, B., Artal, E., Balasini, M., Bernardino, T., Blackhurst, E., Boschini, L., Cappellini, B., Cavaliere, F., Colin, A., Colombo, F., Davis, R. J., De La Fuente, L., Edgeley, J., Gaier, T., Galtress, A., Hoyland, R., Jukkala, P., Kettle, D., Kilpia, V. H., Lawrence, C. R., Lawson, D., Leahy, J. P., Leutenegger, P., Levin, S., Maino, D., Malaspina, M., Mediavilla, A., Miccolis, M., Pagan, L., Pascual, J. P., Pasian, F., Pecora, M., Pospieszalski, M., Roddis, N., Salmon, M. J., Seiffert, M., Silvestri, R., Simonetto, A., Sjoman, P., Sozzi, C., Tuovinen, J., Varis, J., Wilkinson, A., Winder, F., and Universidad de Cantabria
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cosmic microwave background ,media_common.quotation_subject ,miscellaneous [Techniques] ,FOS: Physical sciences ,Low frequency ,01 natural sciences ,7. Clean energy ,Cosmic microwave background ,instruments [Space vehicles] ,techniques-miscellaneous ,CMB physics ,0103 physical sciences ,cosmic microwave background – cosmology ,Black-body radiation ,Space vehicles: instruments ,Instrumentation: detectors ,010303 astronomy & astrophysics ,Instrumentation and Methods for Astrophysics (astro-ph.IM) ,detectors [Instrumentation] ,Remote sensing ,media_common ,Physics ,Noise temperature ,Radiometer ,Techniques: miscellaneous ,observations – space vehicles ,010308 nuclear & particles physics ,Planck ESA mission ,Bandwidth (signal processing) ,Detector ,Astrophysics::Instrumentation and Methods for Astrophysics ,Linearity ,Astronomy and Astrophysics ,Space and Planetary Science ,Sky ,space vehicles-instruments ,instruments ,instrumentation-detectors ,Astrophysics - Instrumentation and Methods for Astrophysics - Abstract
14 páginas, 17 figuras, 15 tablas.-- et al., The Low Frequency Instrument (LFI) on-board the ESA Planck satellite carries eleven radiometer subsystems, called radiometer chain assemblies (RCAs), each composed of a pair of pseudo-correlation receivers. We describe the on-ground calibration campaign performed to qualify the flight model RCAs and to measure their pre-launch performances. Each RCA was calibrated in a dedicated flight-like cryogenic environment with the radiometer front-end cooled to 20 K and the back-end at 300 K, and with an external input load cooled to 4 K. A matched load simulating a blackbody at different temperatures was placed in front of the sky horn to derive basic radiometer properties such as noise temperature, gain, and noise performance, e.g. 1/f noise. The spectral response of each detector was measured as was their susceptibility to thermal variation. All eleven LFI RCAs were calibrated. Instrumental parameters measured in these tests, such as noise temperature, bandwidth, radiometer isolation, and linearity, provide essential inputs to the Planck-LFI data analysis., Planck is a project of the European Space Agency with instruments funded by ESA member states, and with special contributions from Denmark and NASA (USA). The Planck-LFI project is developed by an International Consortium lead by Italy and involving Canada, Finland, Germany, Norway, Spain, Switzerland, UK, USA. The Italian contribution to Planck is supported by the Italian Space Agency (ASI). In Finland, the Planck LFI 70 GHz work was supported by the Finnish Funding Agency for Technology and Innovation (Tekes) T.P.’s work was supported in part by the Academy of Finland grants 205800, 214598, 121703, and 121962. T.P. thank Waldemar von Frenckells stiftelse, Magnus Ehrnrooth Foundation, and Väisälä Foundation for financial support. The Spanish participation is funded by Ministerio de Ciencia e Innovacion through the projects ESP2004-07067-C03-01 and AYA2007-68058- C03-02.
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- 2010
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137. Planck pre-launch status: The Planck-LFI programme
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P. B. Lilje, Amedeo Balbi, Fabio Finelli, S. Leach, Roger J. Hoyland, L. A. Wade, Krzysztof M. Gorski, F. Gasparo, E. Franceschi, Luigi Danese, Jose M. Diego, T. Riller, Christopher G. Paine, M. C. Falvella, Hannu Kurki-Suonio, A. Mennella, Francesca Perrotta, Joseph Silk, Matthias Bartelmann, U. Dörl, L. Mendes, A. Bonaldi, Jose Alberto Rubino-Martin, Carlo Burigana, Sabino Matarrese, Anne Lähteenmäki, G. de Zotti, Torsten A. Enßlin, G. Prézeau, M. Bremer, E. Keihänen, M. Prina, S. Galeotta, M. Sandri, G. De Troia, X. Dupac, L. Popa, L. Pérez-Cuevas, S. Donzelli, Althea Wilkinson, Adam Moss, M. Maris, Alessandro Melchiorri, F. Pasian, Kevin M. Huffenberger, R. Hell, J. Dick, Rafael Rebolo, R. J. Davis, Reijo Keskitalo, F. Gomez, M. López-Caniego, Michael Janssen, Ted Kisner, G. Giardino, Luca Terenzi, Davide Maino, Anna Gregorio, M. Tomasi, N. Mandolesi, F. K. Hansen, Pradeep Bhandari, Eduardo Artal, Fabrizio Villa, Enrique Martínez-González, Charles R. Lawrence, Todd Gaier, J. P. Leahy, O. D'Arcangelo, Andrea Zacchei, T. Passvogel, J. Sternberg, Alessandro Gruppuso, F. Matthai, Julian Borrill, Paolo Cabella, S. Ricciardi, Steven Levin, Jörg P. Rachen, Nicola Vittorio, Peter Meinhold, N. Morisset, Marc Türler, Jussi Varis, Marco Bersanelli, R. Rohlfs, A. Nash, Sergi R. Hildebrandt, B. Cappellini, Diego Herranz, J. Marti-Canales, J. González-Nuevo, Martin White, Douglas Scott, George F. Smoot, R. B. Barreiro, N. Roddis, Emanuele Salerno, Michael Seiffert, P. Vielva, S. N. White, Marcella Massardi, J. A. Tauber, F. Cuttaia, Renzo Nesti, T. Poutanen, A. J. Banday, R. C. Butler, R. D. Davies, Robert C. Bowman, S. R. Lowe, José Miguel Herreros, Luca Stringhetti, Paolo Natoli, J. Tuovinen, H. K. Eriksen, Rodrigo Leonardi, David Pearson, Bruce Partridge, T. Jaffe, G. Polenta, Clive Dickinson, G. de Gasperis, M. Frailis, L. De Angelis, Carlo Baccigalupi, Philip Lubin, C. Cantalupo, A. de Rosa, F. Stivoli, Gianluca Morgante, Andrea Zonca, G. Crone, Luca Valenziano, T. J. L. Courvoisier, M. Malaspina, Carlo Sozzi, Graca Rocha, M. Reinecke, A. Simonetto, G. Morigi, K. Bennett, W. Hovest, Department of Physics, Helsinki Institute of Physics, APC - Cosmologie, AstroParticule et Cosmologie (APC (UMR_7164)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), PLANCK, Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3), Mandolesi, N, Bersanelli, M, BUTLER R., C, Artal, E, Baccigalupi, C, Balbi, A, BANDAY A., J, BARREIRO R., B, Bartelmann, M, Bennett, K, Bhandari, P, Bonaldi, A, Borrill, J, Bremer, M, Burigana, C, BOWMAN R., C, Cabella, P, Cantalupo, C, Cappellini, B, Courvoisier, T, Crone, G, Cuttaia, F, Danese, L, Darcangelo, O, DAVIES R., D, DAVIS R., J, DE ANGELIS, L, DE GASPERIS, G, DE ROSA, A, DE TROIA, G, DE ZOTTI, G, Dick, J, Dickinson, C, DIEGO J., M, Donzelli, S, Dorl, U, Dupac, X, ENLIN T., A, ERIKSEN H., K, FALVELLA M., C, Finelli, F, Frailis, M, Franceschi, E, Gaier, T, Galeotta, S, Gasparo, F, Giardino, G, Gomez, F, GONZALEZ NUEVO, J, GORSKI K., M, Gregorio, Anna, Gruppuso, A, Hansen, F, Hell, R, Herranz, D, HERREROS J., M, Hildebrandt, S, Hovest, W, Hoyland, R, Huffenberger, K, Janssen, M, Jaffe, T, Keihanen, E, Keskitalo, R, Kisner, T, KURKI SUONIO, H, Lahteenmaki, A, LAWRENCE C., R, M., S, J., Leach, Leahy, P, Leonardi, R, Levin, S, LILJE P., B, LOPEZ CANIEGO, M, LOWE S., R, LUBIN P., M, Maino, D, Malaspina, M, Maris, M, MARTI CANALES, J, MARTINEZ GONZALEZ, E, Massardi, M, Matarrese, S, Matthai, F, Meinhold, P, Melchiorri, A, Mendes, L, Mennella, A, Morgante, G, Morigi, G, Morisset, N, Moss, A, Nash, A, Natoli, P, Nesti, R, Paine, C, Partridge, B, Pasian, F, Passvogel, T, Pearson, D, PEREZ CUEVAS, L, Perrotta, F, Polenta, G, POPA L., A, Poutanen, T, Prezeau, G, Prina, M, RACHEN J., P, Rebolo, R, Reinecke, M, Ricciardi, S, Riller, T, Rocha, G, Roddis, N, Rohlfs, R, RUBINO MARTIN J., A, Salerno, E, Sandri, M, Scott, D, Seiffert, M, Silk, J, Simonetto, A, SMOOT G., F, Sozzi, C, Sternberg, J, Stivoli, F, Stringhetti, L, Tauber, J, Terenzi, L, Tomasi, M, Tuovinen, J, Turler, M, Valenziano, L, Varis, J, Vielva, P, Villa, F, Vittorio, N, Wade, L, White, M, White, S, Wilkinson, A, Zacchei, A, Zonca, A., Physique Corpusculaire et Cosmologie - Collège de France (PCC), Collège de France (CdF)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Collège de France (CdF)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-AstroParticule et Cosmologie (APC (UMR_7164)), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Observatoire de Paris, PSL Research University (PSL)-PSL Research University (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Observatoire de Paris, PSL Research University (PSL)-PSL Research University (PSL)-Université Paris Diderot - Paris 7 (UPD7), and Universidad de Cantabria
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Electromagnetic spectrum ,[SDU.ASTR.CO]Sciences of the Universe [physics]/Astrophysics [astro-ph]/Cosmology and Extra-Galactic Astrophysics [astro-ph.CO] ,submillimeter: generaltelescopes ,cosmic microwave background ,space vehicles: instruments ,submillimeter: general ,instrumentation: polarimeters ,telescopes ,instrumentation: detectors ,Cosmic microwave background ,data analysis ,Astrophysics ,general [Submillimeter] ,7. Clean energy ,01 natural sciences ,LARGE-AREA TELESCOPE ,CMB physics ,cosmic microwave backgroundin ,010303 astronomy & astrophysics ,detectors [Instrumentation] ,media_common ,Physics ,Data processing ,Planck ESA mission ,Galactic and extragalactic asrophysics ,Astrophysics::Instrumentation and Methods for Astrophysics ,STRAYLIGHT CONTAMINATION ,LOW-FREQUENCY INSTRUMENT ,DMR SKY MAPS ,MICROWAVE BACKGROUND MAPS ,galactic and extragalactic astrophysics ,symbols ,Astrophysics - Instrumentation and Methods for Astrophysics ,Astrophysics - Cosmology and Nongalactic Astrophysics ,GALACTIC FOREGROUNDS ,Cosmology and Nongalactic Astrophysics (astro-ph.CO) ,[PHYS.ASTR.IM]Physics [physics]/Astrophysics [astro-ph]/Instrumentation and Methods for Astrophysic [astro-ph.IM] ,COMPONENT SEPARATION ,Cosmic microwawe background ,media_common.quotation_subject ,ANGULAR POWER SPECTRA ,education ,strumentation: detectors ,FOS: Physical sciences ,Context (language use) ,Astrophysics::Cosmology and Extragalactic Astrophysics ,114 Physical sciences ,[PHYS.ASTR.CO]Physics [physics]/Astrophysics [astro-ph]/Cosmology and Extra-Galactic Astrophysics [astro-ph.CO] ,instruments [Space vehicles] ,symbols.namesake ,Settore FIS/05 - Astronomia e Astrofisica ,0103 physical sciences ,Calibration ,Ground segment ,Planck ,Instrumentation and Methods for Astrophysics (astro-ph.IM) ,DATA-PROCESSING CENTERS ,Remote sensing ,polarimeters [Instrumentation] ,010308 nuclear & particles physics ,Astronomy and Astrophysics ,calibration ,115 Astronomy, Space science ,[SDU.ASTR.IM]Sciences of the Universe [physics]/Astrophysics [astro-ph]/Instrumentation and Methods for Astrophysic [astro-ph.IM] ,Space and Planetary Science ,Sky ,NON-GAUSSIANITY ,space vehicles ,Telescopes - Abstract
24 páginas, 16 figuras, 5 tablas.-- et al., This paper provides an overview of the Low Frequency Instrument (LFI) programme within the ESA Planck mission. The LFI instrument has been developed to produce high precision maps of the microwave sky at frequencies in the range 27–77 GHz, below the peak of the cosmic microwave background (CMB) radiation spectrum. The scientific goals are described, ranging from fundamental cosmology to Galactic and extragalactic astrophysics. The instrument design and development are outlined, together with the model philosophy and testing strategy. The instrument is presented in the context of the Planck mission. The LFI approach to ground and inflight calibration is described. We also describe the LFI ground segment. We present the results of a number of tests demonstrating the capability of the LFI data processing centre (DPC) to properly reduce and analyse LFI flight data, from telemetry information to calibrated and cleaned time ordered data, sky maps at each frequency (in temperature and polarization), component emission maps (CMB and diffuse foregrounds), catalogs for various classes of sources (the Early Release Compact Source Catalogue and the Final Compact Source Catalogue). The organization of the LFI consortium is briefly presented as well as the role of the core team in data analysis and scientific exploitation. All tests carried out on the LFI flight model demonstrate the excellent performance of the instrument and its various subunits. The data analysis pipeline has been tested and its main steps verified. In the first three months after launch, the commissioning, calibration, performance, and verification phases will be completed, after which Planck will begin its operational life, in which LFI will have an integral part., The Planck-LFI project is developed by an International Consortium led by Italy and involving Canada, Finland, Germany, Norway, Spain, Switzerland, UK and USA. The Italian contribution to Planck is supported by the Agenzia Spaziale Italiana (ASI) and INAF. We also wish to thank the many people of the Herschel/Planck Project and RSSD of ESA, ASI, THALES Alenia Space Industries and the LFI Consortium that have contributed to the realization of LFI. We are grateful to our HFI colleagues for such a fruitful collaboration during so many years of common work. The German participation at the Max-Planck-Institut für Astrophysik is funded by the Bundesministerium für Wirtschaft und Technologie through the Raumfahrt- Agentur of the Deutsches Zentrum für Luft- und Raumfahrt (DLR) [FKZ: 50 OP 0901] and by the Max-Planck-Gesellschaft (MPG). The Finnish contribution is supported by the Finnish Funding Agency for Technology and Innovation (Tekes) and the Academy of Finland. The Spanish participation is funded by Ministerio de Ciencia e Innovacion through the project ESP2004-07067-C03 and AYA2007-68058-C03. The UK contribution is supported by the Science and Technology Facilities Council (STFC). C. Baccigalupi and F. Perrotta acknowledge partial support of the NASA LTSA Grant NNG04CG90G.
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- 2010
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138. PLANCK-LFI: OPERATION OF THE SCIENTIFIC GROUND SEGMENT
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A. Zacchei, G. de Gasperis, F. Gasparo, F. Stivoli, Claudio Vuerli, S. Fogliani, Michele Maris, M. Malaspina, Anna Gregorio, Luca Stringhetti, P. Manzato, Carlo Burigana, Gianluca Morgante, Rc Butler, Nazzareno Mandolesi, X. Dupac, M. Sandri, S. Leach, A. Mennella, Fabio Pasian, Giuliano Taffoni, Davide Maino, M. Bersanelli, C. Baccigalupi, Luca Valenziano, F. Perrotta, F. Villa, Gianmarco Maggio, Pasian, F, Zacchei, A, Maris, M, Fogliani, S, Dupac, X, Taffoni, G, Vuerli, C, Manzato, P, Gasparo, F, Maggio, G, Gregorio, Anna, Maino, D, Mennella, A, Bersanelli, M, Baccigalupi, C, Perrotta, F, Leach, S, Stivoli, F, Butler, Rc, Burigana, C, Malaspina, M, Morgante, G, Sandri, M, Stringhetti, L, Valenziano, L, Villa, F, Mandolesi, N, and DE GASPERIS, G.
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Data processing ,Engineering ,Payload ,business.industry ,media_common.quotation_subject ,Emphasis (telecommunications) ,Astrophysics::Instrumentation and Methods for Astrophysics ,Radio spectrum ,symbols.namesake ,Settore FIS/05 - Astronomia e Astrofisica ,Sky ,Range (aeronautics) ,symbols ,Ground segment ,Planck ,business ,Remote sensing ,media_common - Abstract
Planck is an ESA mission due to be launched in August 2007 with a payload of two instruments aimed at mapping the microwave sky in 9 frequency bands in the 30-850 GHz range. In this paper, after an introduction describing the basics of the Planck mission and the technical characteristics of the Low Frequency Instrument (LFI), the ground segment activities are discussed, with special emphasis on the monitoring of instrument behaviour, data processing and computational challenges, with a discussion of the foreseen solutions.
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- 2006
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139. "Looking at nothing": An implicit ocular motor index of face recognition in developmental prosopagnosia.
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Rahavi A, Malaspina M, Albonico A, and Barton JJS
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Subjects often look towards to previous location of a stimulus related to a task even when that stimulus is no longer visible. In this study we asked whether this effect would be preserved or reduced in subjects with developmental prosopagnosia. Participants learned faces presented in video-clips and then saw a brief montage of four faces, which was replaced by a screen with empty boxes, at which time they indicated whether the learned face had been present in the montage. Control subjects were more likely to look at the blank location where the learned face had appeared, on both hit and miss trials, though the effect was larger on hit trials. Prosopagnosic subjects showed a reduced effect, though still better on hit than on miss trials. We conclude that explicit accuracy and our implicit looking at nothing effect are parallel effects reflecting the strength of the neural activity underlying face recognition.
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- 2023
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140. Contrasting domain-general and domain-specific accounts in cognitive neuropsychology: An outline of a new approach with developmental prosopagnosia as a case.
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Gerlach C, Barton JJS, Albonico A, Malaspina M, and Starrfelt R
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- Humans, Cognition, Prosopagnosia
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The backbone of cognitive neuropsychology is the observation of (double) dissociations in performance between patients, suggesting some degree of independence between cognitive processes (domain specificity). In comparison, observations of associations between disorders/deficits have been deemed less evidential in neuropsychological theorizing about cognitive architecture. The reason is that associations can reflect damage to independent cognitive processes that happen to be mediated by structures commonly affected by the same brain disorder rather than damage to a shared (domain-general) mechanism. Here we demonstrate that it is in principle possible to discriminate between these alternatives by means of a procedure involving large unbiased samples. We exemplify the procedure in the context of developmental prosopagnosia (DP), but the procedure is in principle applicable to all neuropsychological deficits/disorders. A simulation of the procedure on a dataset yields estimates of dissociations/associations that are well in line with existing DP-studies, and also suggests that seemingly selective disorders can reflect damage to both domain-general and domain-specific cognitive processes. However, the simulation also highlights some limitations that should be considered if the procedure is to be applied prospectively. The main advantage of the procedure is that allows for examination of both associations and dissociations in the same sample. Hence, it may help even the balance in the use of associations and dissociations as grounds for neuropsychological theorizing., (© 2022. The Psychonomic Society, Inc.)
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- 2022
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141. An ocular motor index of rapid face recognition: The 'looking-at-nothing' effect.
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Malaspina M, Albonico A, Rahavi A, and Barton JJS
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- Eye Movements, Fixation, Ocular, Humans, Learning, Facial Recognition physiology
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In the looking at nothing effect, subjects performing a task involving stimuli that are no longer visible tend to fixate the regions on an empty screen where those stimuli had been located. We performed three experiments to examine whether this effect could serve as an index of short-term face recognition. Subjects saw a short video of a person's face and then saw briefly a choice screen of four faces, followed by a screen with empty boxes, after which they responded whether the learned face was one of the four. Fixations made while the screen without faces was present were more likely to be directed towards the target face when it had been shown, and this was the case not only on hit trails, but also on miss trials. Examining fixations made during a 3-second window showed that this looking at nothing effect was present for the first fixation only, after which subjects were more likely to fixate the other empty boxes, a 'looking away from nothing' effect. Including data from all three experiments showed an age-related decline in discriminative sensitivity but not in the looking at nothing effect. However, there was a positive correlation between discriminative sensitivity and the looking at nothing effect. We conclude that the looking at nothing effect can index rapid face recognition, that it is related to explicit discriminative performance, and that its short-term dynamics bear similarities to inhibition of return., (Copyright © 2022. Published by Elsevier B.V.)
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- 2022
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142. Accuracy of different triage strategies for human papillomavirus positivity in an Italian screening population.
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Gustinucci D, Benevolo M, Cesarini E, Mancuso P, Passamonti B, Giaimo MD, Corvetti R, Nofrini V, Bulletti S, Malaspina M, Tintori B, and Giorgi Rossi P
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- Cyclin-Dependent Kinase Inhibitor p16 analysis, Female, Genotype, Human Papillomavirus DNA Tests, Human papillomavirus 16 genetics, Human papillomavirus 18 genetics, Humans, Ki-67 Antigen analysis, Human papillomavirus 16 isolation & purification, Human papillomavirus 18 isolation & purification, Triage, Uterine Cervical Neoplasms virology, Uterine Cervical Dysplasia virology
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How to manage human papillomavirus (HPV)-positive women in cervical cancer screening remains debated. Our study compared different strategies to triage HPV positivity in a large cohort of women participating in a population HPV-based screening program. Women were tested for HPV (Cobas 4800; Roche), and those positive were triaged with cytology; cytology-positives were referred to colposcopy, while negatives were referred to 1-year HPV retesting. All HPV-positive women were also evaluated with p16/ki67 dual staining (Roche). All lesions found within 24 months of follow-up were included in the analyses. Of the 70 146 women tested, 4757 (6.8%) were HPV-positive. Of these, 1090 were cytology-positive and were referred to colposcopy. Of the 2958 HPV-positive/cytology-negative women who presented at 1-year retesting, 1752 (59.9%) still tested positive. Cumulatively, 532 CIN2+ (including 294 CIN3+) were found. The sensitivity of cytology, HPV16/18 and p16/ki67 as triage test for CIN3+ was 67.9%, 56.0% and 85.0%, respectively. The positive predictive value (PPV) for immediate colposcopy referral was 21.0%, 15.8% and 22.9%, respectively. Combining cytology with typing increased sensitivity to 83.9% and lowered PPV to 14.8%, while combining p16/ki67 and typing increased sensitivity to 91.1%, lowering the PPV to 15.9%. Women negative to p16/ki67 triage presented a cumulative 1-year CIN3+ risk of about 1%. In conclusion, when triaging HPV positivity, p16/ki67 performed better than cytology with or without HPV16/18 genotyping. The strategies that included dual staining achieved sensitivity and low 1-year risk for CIN3+ sufficiently high enough to permit considering extending the surveillance interval to 2 to 3 years for HPV-positive/triage-negative women., (© 2021 UICC.)
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- 2022
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143. The persistence of remote visual semantic memory following ocular blindness.
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Dietz CD, Malaspina M, Albonico A, and Barton JJS
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- Cross-Sectional Studies, Humans, Memory, Vision, Ocular, Blindness complications, Semantics
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Subjects with complete ocular blindness in both eyes provide a unique opportunity to study the long-term durability of visual semantic memory. In this cross-sectional study we recruited eleven subjects who had acquired blindness for between 1 and 36 years. For comparison, we studied four subjects with congenital blindness and seventeen age- and sex-matched sighted control subjects. We administered ten forced-choice questionnaires that probed one auditory category and four visual categories, namely object shape and size; object hue and lightness; word and letter shape; and the shape and features of famous faces. Subjects with congenital blindness performed worse than controls on all visual categories, but nevertheless performed better than chance on object structure or colour, suggesting that the answers to some questions about visual properties can be derived from haptic or non-visual semantic information. Subjects with acquired blindness performed similarly to controls on all categories except for facial memory, particularly for facial features. We conclude that there is a substantial "permastore" of visual semantic memory but that facial memories are less durable, perhaps indicating that they are either less over-learned or more dependent on visual representations than other forms of visual object information., (Copyright © 2021 Elsevier Ltd. All rights reserved.)
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- 2022
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144. The Focal Attention Window Size Explains Letter Substitution Errors in Reading.
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Daini R, Primativo S, Albonico A, Veronelli L, Malaspina M, Corbo M, Martelli M, and Arduino LS
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Acquired Neglect Dyslexia is often associated with right-hemisphere brain damage and is mainly characterized by omissions and substitutions in reading single words. Martelli et al. proposed in 2011 that these two types of error are due to different mechanisms. Omissions should depend on neglect plus an oculomotor deficit, whilst substitutions on the difficulty with which the letters are perceptually segregated from each other (i.e., crowding phenomenon). In this study, we hypothesized that a deficit of focal attention could determine a pathological crowding effect, leading to imprecise letter identification and consequently substitution errors. In Experiment 1, three brain-damaged patients, suffering from peripheral dyslexia, mainly characterized by substitutions, underwent an assessment of error distribution in reading pseudowords and a T detection task as a function of cue size and timing, in order to measure focal attention. Each patient, when compared to a control group, showed a deficit in adjusting the attentional focus. In Experiment 2, a group of 17 right-brain-damaged patients were asked to perform the focal attention task and to read single words and pseudowords as a function of inter-letter spacing. The results allowed us to confirm a more general association between substitution-type reading errors and the performance in the focal attention task.
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- 2021
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145. Search for Face Identity or Expression: Set Size Effects in Developmental Prosopagnosia.
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Djouab S, Albonico A, Yeung SC, Malaspina M, Mogard A, Wahlberg R, Corrow SL, and Barton JJS
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- Adult, Aged, Female, Humans, Male, Middle Aged, Facial Expression, Facial Recognition physiology, Prosopagnosia physiopathology, Recognition, Psychology physiology, Social Perception
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The set size effect during visual search indexes the effects of processing load and thus the efficiency of perceptual mechanisms. Our goal was to investigate whether individuals with developmental prosopagnosia show increased set size effects when searching faces for face identity and how this compares to search for face expression. We tested 29 healthy individuals and 13 individuals with developmental prosopagnosia. Participants were shown sets of three to seven faces to judge whether the identities or expressions of the faces were the same across all stimuli or if one differed. The set size effect was the slope of the linear regression between the number of faces in the array and the response time. Accuracy was similar in both controls and prosopagnosic participants. Developmental prosopagnosic participants displayed increased set size effects in face identity search but not in expression search. Single-participant analyses reveal that 11 developmental prosopagnosic participants showed a putative classical dissociation, with impairments in identity but not expression search. Signal detection theory analysis showed that identity set size effects were highly reliable in discriminating prosopagnosic participants from controls. Finally, the set size ratios of same to different trials were consistent with the predictions of self-terminated serial search models for control participants and prosopagnosic participants engaged in expression search but deviated from those predictions for identity search by the prosopagnosic cohort. We conclude that the face set size effect reveals a highly prevalent and selective perceptual inefficiency for processing face identity in developmental prosopagnosia.
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- 2020
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146. Geospatial analysis of the influence of family doctor on colorectal cancer screening adherence.
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Stracci F, Gili A, Naldini G, Gianfredi V, Malaspina M, Passamonti B, and Bianconi F
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- Aged, Colonoscopy, Female, Geography, Humans, Italy, Male, Middle Aged, Sex Factors, Colorectal Neoplasms diagnosis, Mass Screening statistics & numerical data, Patient Compliance statistics & numerical data, Physician-Patient Relations, Physicians, Family psychology
- Abstract
Background: Despite the well-recognised relevance of screening in colorectal cancer (CRC) control, adherence to screening is often suboptimal. Improving adherence represents an important public health strategy. We investigated the influence of family doctors (FDs) as determinant of CRC screening adherence by comparing each FDs practice participation probability to that of the residents in the same geographic areas using the whole population geocoded., Methods: We used multilevel logistic regression model to investigate factors associated with CRC screening adherence, among 333,843 people at their first screening invitation. Standardized Adherence Rates (SAR) by age, gender, and socioeconomic status were calculated comparing FDs practices to the residents in the same geographic areas using geocoded target population., Results: Screening adherence increased from 41.0% (95% CI, 40.8-41.2) in 2006-2008 to 44.7% (95% CI, 44.5-44.9) in 2011-2012. Males, the most deprived and foreign-born people showed low adherence. FD practices and the percentage of foreign-born people in a practice were significant clustering factors. SAR for 145 (21.4%) FDs practices differed significantly from people living in the same areas. Predicted probabilities of adherence were 31.7% and 49.0% for FDs with low and high adherence, respectively., Discussion: FDs showed a direct and independent effect to the CRC screening adherence of the people living in their practice. FDs with significantly high adherence level could be the key to adherence improvement., Impact: Most deprived individuals and foreigners represent relevant targets for interventions in public health aimed to improve CRC screening adherence., Competing Interests: The authors declare that they have no potential competing financial and non-financial interests.
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- 2019
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147. Self-face and self-body advantages in congenital prosopagnosia: evidence for a common mechanism.
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Malaspina M, Albonico A, and Daini R
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- Adult, Facial Recognition physiology, Female, Humans, Male, Prosopagnosia physiopathology, Young Adult, Face, Foot, Hand, Pattern Recognition, Visual physiology, Prosopagnosia congenital, Recognition, Psychology physiology, Self Concept
- Abstract
Prosopagnosia is a disorder leading to difficulties in recognizing faces. However, recent evidence suggests that individuals with congenital prosopagnosia can achieve considerable accuracy when they have to recognize their own faces (self-face advantage). Yet, whether this advantage is face-specific or not is still unclear. Here, we aimed to investigate whether individuals with congenial prosopagnosia show a self-advantage also in recognizing other self body-parts and, if so, whether the advantage for the body parts differs from the one characterizing the self-face. Eight individuals with congenital prosopagnosia and 22 controls underwent a delayed matching task in which they were required to recognize faces, hands and feet belonging to the self or to others. Controls showed a similar self-advantage for all the stimuli tested; by contrast, individuals with congenital prosopagnosia showed a larger self-advantage with faces compared to hands and feet, mainly driven by their deficit with others' faces. In both groups the self-advantages for the different body parts were strongly and significantly correlated. Our data suggest that the self-face advantage showed by individuals with congenital prosopagnosia is not face-specific and that the same mechanism could be responsible for both the self-face and self body-part advantages.
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- 2019
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148. A comparative effectiveness trial of two faecal immunochemical tests for haemoglobin (FIT). Assessment of test performance and adherence in a single round of a population-based screening programme for colorectal cancer.
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Passamonti B, Malaspina M, Fraser CG, Tintori B, Carlani A, D'Angelo V, Galeazzi P, Di Dato E, Mariotti L, Bulletti S, D'Amico MR, Gustinucci D, Martinelli N, Spita N, Cesarini E, Rubeca T, Giaimo M, Segnan N, and Senore C
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- Aged, Comparative Effectiveness Research, Female, Humans, Male, Middle Aged, Predictive Value of Tests, Colorectal Neoplasms diagnosis, Early Detection of Cancer methods, Feces chemistry, Hemoglobins analysis, Patient Acceptance of Health Care statistics & numerical data
- Abstract
Aim: To compare acceptability and diagnostic accuracy of a recently available faecal immunochemical test (FIT) system (HM-JACKarc) with the FIT routinely used in an established screening programme (OC-Sensor)., Design: Randomised controlled trial (ISRCTN20086618) within a population-based colorectal cancer (CRC) screening programme. Subjects eligible for invitation in the Umbria Region (Italy) programme were randomised (ratio 1:1) to be screened using one of the FIT systems., Results: Screening uptake among the 48 888 invitees was the same for both systems among subjects invited in the first round and higher with OC-Sensor than with HM-JACKarc (relative risk (RR): 1.03; 95% CI 1.02 to 1.04) among those invited in subsequent rounds. Positivity rate (PR) was similar with OC-Sensor (6.5%) as with HM-JACKarc (6.2%) among subjects performing their first FIT screening and higher with OC-Sensor (5.6%, RR: 1.25, 95% CI 1.12 to 1.40) than with HM-JACKarc (4.4%) among those screened in previous rounds. Positive predictive value (PPV) (OC-Sensor: 25.9%, HM-JACKarc: 25.6%) and detection rate (DR) (OC-Sensor: 1.40%; HM-JACKarc: 1.42%) for advanced neoplasia (AN: CRC + advanced adenoma) were similar among subjects performing their first FIT screening. The differences in the AN PPV (OC-Sensor: 20.3%, HM-JACKarc: 22.6%) and DR (OC-Sensor: 0.96%, HM-JACKarc: 0.83%) among those screened in previous rounds were not statistically significant. The number needed to scope to detect one AN was 3.9 (95% CI 5.8 to 2.9) and 3.9 (95% CI 5.5 to 2.9) at first and 4.9 (95% CI 5.8 to 4.2) and 4.4 (95% CI 5.3 to 3.7) at subsequent screening, with OC-Sensor and HM-JACKarc, respectively., Conclusions: Our results suggest that acceptability and diagnostic performance of HM-JACKarc and of OC-Sensor systems are similar in a screening setting., Trial Registration Number: ISRCTN20086618; Results., Competing Interests: Competing interests: CGF has undertaken paid consultancy with Immunostics and Kyowa Medex, and received funding for attendance at meetings from Alpha Labs. CS (past 2 years): received support by Medical System for travel and accommodation at a scientific meeting in Italy. His Institution receives PillCam Colon devices from Covidien-Given Imaging to conduct a study and, during 2014, it has received without charge, from EndoChoice, Fuse endoscopy systems to conduct a trial., (Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.)
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- 2018
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149. Mapping self-face recognition strategies in congenital prosopagnosia.
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Malaspina M, Albonico A, Lao J, Caldara R, and Daini R
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- Adult, Discrimination, Psychological, Face, Female, Fixation, Ocular, Humans, Male, Prosopagnosia congenital, Psychomotor Performance, Reaction Time, Recognition, Psychology, Visual Fields, Young Adult, Eye Movements, Facial Recognition, Prosopagnosia psychology
- Abstract
Objective: Recent evidence showed that individuals with congenital face processing impairment (congenital prosopagnosia [CP]) are highly accurate when they have to recognize their own face (self-face advantage) in an implicit matching task, with a preference for the right-half of the self-face (right perceptual bias). Yet the perceptual strategies underlying this advantage are unclear. Here, we aimed to verify whether both the self-face advantage and the right perceptual bias emerge in an explicit task, and whether those effects are linked to a different scanning strategy between the self-face and unfamiliar faces., Method: Eye movements were recorded from 7 CPs and 13 controls, during a self/other discrimination task of stimuli depicting the self-face and another unfamiliar face, presented upright and inverted., Results: Individuals with CP and controls differed significantly in how they explored faces. In particular, compared with controls, CPs used a distinct eye movement sampling strategy for processing inverted faces, by deploying significantly more fixations toward the nose and mouth areas, which resulted in more efficient recognition. Moreover, the results confirmed the presence of a self-face advantage in both groups, but the eye movement analyses failed to reveal any differences in the exploration of the self-face compared with the unfamiliar face. Finally, no bias toward the right-half of the self-face was found., Conclusions: Our data suggest that the self-face advantage emerges both in implicit and explicit recognition tasks in CPs as much as in good recognizers, and it is not linked to any specific visual exploration strategies. (PsycINFO Database Record, ((c) 2018 APA, all rights reserved).)
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- 2018
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150. Guidance for faecal occult blood testing: quantitative immunochemical method (FIT-HB) in colorectal cancer screening programmes.
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Rubeca T, Rapi S, Deandrea S, Malaspina M, Passamonti BU, Grassi E, Cioccarelli AM, Marchetti E, Boni M, Cellai F, Pradella M, Gattafoni F, and Rotolo S
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- Accreditation standards, Certification standards, Early Detection of Cancer methods, Early Detection of Cancer standards, Guideline Adherence, Hemoglobinometry instrumentation, Hemoglobinometry methods, Hemoglobinometry standards, Humans, Immunoassay instrumentation, Immunoassay standards, Indicators and Reagents, Italy, Methods, Protein Stability, Quality Control, Reagent Kits, Diagnostic, Specimen Handling, Colorectal Neoplasms diagnosis, Immunoassay methods, Occult Blood
- Abstract
Background: in Italy, colorectal cancer screening is included as part of the Italian National Health Service - SSN (Servizio Sanitario Nazionale) Essential Levels of Care - LEA (Livelli Essenziali Assistenziali) and the European Guidelines, which specify quantitative FIT-Hb testing as the best strategy for organised screening programmes. To ensure consistent operating standards in Member States, European regulations require the implementation of certification and accreditation requirements for diagnostic and care-related processes. The requirement, based on ISO 17021 accreditation standards, includes ISO 9001 certification for systems and ISO 15189:2012 accreditation for laboratories., Methodology: various phases of the analytical process (pre-test, test, post-test) were evaluated in detail and provided operational guidelines for adjusting analytical and managerial procedures using: (a) feedback from members of GISCoR screening labs; (b) performance data obtained via a systematic review of the literature and the Osservatorio Nazionale Screening (ONS) Survey; (c) recommendations for laboratory practice issued by the World Endoscopy Organization "FIT for Screening" Working Group; (d) selected guidelines from the National Guidelines Clearinghouse database; and (e) Canadian, Australian and European screening programme websites. With respect to ISO 15189:2012 standards for accreditation of medical laboratories, GISCoR's guidance has been re-evaluated and revised by auditors from the Italian certification body (ACCREDIA) to assess its compliance and completeness with the aim of finalising operating procedures., Conclusions: the implementation and maintenance of operational standards required by complex systems (e.g. screening programmes) involving constant interaction between facilities and the supporting organisational structure are not easy to achieve. The guide aims to provide laboratories with the necessary guidance for proper process management.
- Published
- 2017
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